Alexander Sorkin - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Cell Biology

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Pinilla-Macua I, Sorkin A. Cbl and Cbl-b independently regulate EGFR through distinct receptor interaction modes. Molecular Biology of the Cell. mbcE23020058. PMID 37903221 DOI: 10.1091/mbc.E23-02-0058  0.403
2022 Surve S, Sorkin A. CRISPR/Cas9 Gene Editing of HeLa Cells to Tag Proteins with mNeonGreen. Bio-Protocol. 12: e4415. PMID 35813028 DOI: 10.21769/BioProtoc.4415  0.372
2022 Perez Verdaguer M, Zhang T, Surve S, Paulo JA, Wallace C, Watkins SC, Gygi SP, Sorkin A. Time-resolved proximity labeling of protein networks associated with ligand-activated EGFR. Cell Reports. 39: 110950. PMID 35705039 DOI: 10.1016/j.celrep.2022.110950  0.546
2021 Surve S, Watkins SC, Sorkin A. EGFR-RAS-MAPK signaling is confined to the plasma membrane and associated endorecycling protrusions. The Journal of Cell Biology. 220. PMID 34515735 DOI: 10.1083/jcb.202107103  0.36
2021 Perez Verdaguer M, Zhang T, Paulo JA, Gygi S, Watkins SC, Sakurai H, Sorkin A. Mechanism of p38 MAPK-induced EGFR endocytosis and its crosstalk with ligand-induced pathways. The Journal of Cell Biology. 220. PMID 34032851 DOI: 10.1083/jcb.202102005  0.459
2021 von Zastrow M, Sorkin A. Mechanisms for Regulating and Organizing Receptor Signaling by Endocytosis. Annual Review of Biochemistry. PMID 33606955 DOI: 10.1146/annurev-biochem-081820-092427  0.495
2020 Li H, Pinilla-Macua I, Ouyang Y, Sadovsky E, Kajiwara K, Sorkin A, Sadovsky Y. Internalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies. Journal of Extracellular Vesicles. 9: 1812261. PMID 32944196 DOI: 10.1080/20013078.2020.1812261  0.335
2020 Ouyang Y, Mouillet JF, Sorkin A, Sadovsky Y. Trophoblastic extracellular vesicles and viruses: Friends or foes? American Journal of Reproductive Immunology (New York, N.Y. : 1989). e13345. PMID 32939907 DOI: 10.1111/Aji.13345  0.316
2020 Estadella I, Pedrós-Gámez O, Colomer-Molera M, Bosch M, Sorkin A, Felipe A. Endocytosis: A Turnover Mechanism Controlling Ion Channel Function. Cells. 9. PMID 32759790 DOI: 10.3390/Cells9081833  0.431
2019 Verdaguer MP, Larsen MB, Bruchez MP, Watkins SC, Sorkin A. Analysis of EGF Receptor Endocytosis Using Fluorogen Activating Protein Tagged Receptor. Bio-Protocol. 9: e3463. PMID 33654955 DOI: 10.21769/BioProtoc.3463  0.505
2019 Cheng MH, Ponzoni L, Sorkina T, Lee JY, Zhang S, Sorkin A, Bahar I. Trimerization of dopamine transporter triggered by AIM-100 binding: Molecular mechanism and effect of mutations. Neuropharmacology. 107676. PMID 31228486 DOI: 10.1016/J.Neuropharm.2019.107676  0.305
2019 Larsen MB, Perez Verdaguer M, Schmidt BF, Bruchez MP, Watkins SC, Sorkin A. Generation of endogenous pH-sensitive EGF receptor and its application in high-throughput screening for proteins involved in clathrin-mediated endocytosis. Elife. 8. PMID 31066673 DOI: 10.7554/Elife.46135  0.536
2019 Perez Verdaguer M, Larsen M, Bruchez M, Watkins S, Sorkin A. Analysis of EGF Receptor Endocytosis Using Fluorogen Activating Protein Tagged Receptor Bio-Protocol. 9. DOI: 10.21769/bioprotoc.3463  0.441
2018 Surve SV, Myers PJ, Clayton SA, Watkins SC, Lazzara MJ, Sorkin A. Localization dynamics of endogenous fluorescently-labeled RAF1 in EGF-stimulated cells. Molecular Biology of the Cell. mbcE18080512. PMID 30586319 DOI: 10.1091/Mbc.E18-08-0512  0.407
2018 Sorkina T, Ma S, Larsen MB, Watkins SC, Sorkin A. Small molecule induced oligomerization, clustering and clathrin-independent endocytosis of the dopamine transporter. Elife. 7. PMID 29630493 DOI: 10.7554/Elife.32293  0.323
2018 Martínez-Mármol R, Styrczewska K, Pérez-Verdaguer M, Vallejo-Gracia A, Comes N, Sorkin A, Felipe A. PKC Activation Induces Ubiquitination-Dependent KV1.3 Endocytosis Mediated by Nedd4-2 Ubiquitin Ligase Biophysical Journal. 114: 301a. DOI: 10.1016/J.Bpj.2017.11.1713  0.375
2017 Pinilla-Macua I, Grassart A, Duvvuri U, Watkins SC, Sorkin A. EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo. Elife. 6. PMID 29268862 DOI: 10.7554/Elife.31993  0.554
2017 Martínez-Mármol R, Styrczewska K, Pérez-Verdaguer M, Vallejo-Gracia A, Comes N, Sorkin A, Felipe A. Ubiquitination mediates Kv1.3 endocytosis as a mechanism for protein kinase C-dependent modulation. Scientific Reports. 7: 42395. PMID 28186199 DOI: 10.1038/Srep42395  0.378
2017 Pinilla-Macua I, Grassart A, Duvvuri U, Watkins SC, Sorkin A. Author response: EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo Elife. DOI: 10.7554/Elife.31993.020  0.467
2017 Styrczewska K, Martínez-Mármol R, Comes N, Estadella I, Pérez-Verdaguer M, Pujadas L, Soriano E, Sorkin A, Felipe A. ERK1/2 Mediates EGF-Dependent Kv1.3 Endocytosis Biophysical Journal. 112: 251a-252a. DOI: 10.1016/J.Bpj.2016.11.1374  0.481
2016 Pinilla-Macua I, Watkins SC, Sorkin A. Endocytosis separates EGF receptors from endogenous fluorescently labeled HRas and diminishes receptor signaling to MAP kinases in endosomes. Proceedings of the National Academy of Sciences of the United States of America. 113: 2122-7. PMID 26858456 DOI: 10.1073/Pnas.1520301113  0.566
2016 Sorkin A, Pinilla-Macua I. Endocytosis Separates EGF Receptors From Endogenous Fluorescently Labeled HRas and Prevents Receptor Signaling to MAP Kinases in Endosomes The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.256.1  0.623
2016 Pinilla-Macua I, Watkins SC, Sorkin A. Endocytosis separates EGF receptors from endogenous fluorescently labeled HRas and diminishes receptor signaling to MAP kinases in endosomes Proceedings of the National Academy of Sciences of the United States of America. 113: 2122-2127. DOI: 10.1073/pnas.1520301113  0.484
2015 Martínez-Mármol R, Comes N, Styrczewska K, Pérez-Verdaguer M, Vicente R, Pujadas L, Soriano E, Sorkin A, Felipe A. Unconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosis. Cellular and Molecular Life Sciences : Cmls. PMID 26542799 DOI: 10.1007/S00018-015-2082-0  0.549
2015 Block ER, Nuttle J, Balcita-Pedicino JJ, Caltagarone J, Watkins SC, Sesack SR, Sorkin A. Brain Region-Specific Trafficking of the Dopamine Transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12845-58. PMID 26377471 DOI: 10.1523/Jneurosci.1391-15.2015  0.305
2015 Pinilla-Macua I, Sorkin A. Methods to study endocytic trafficking of the EGF receptor. Methods in Cell Biology. 130: 347-67. PMID 26360045 DOI: 10.1016/Bs.Mcb.2015.05.008  0.605
2015 Fortian A, Dionne LK, Hong SH, Kim W, Gygi SP, Watkins S, Sorkin A. Endocytosis of ubiquitylation-deficient EGF receptor mutants via clathrin coated pits is mediated by ubiquitylation. Traffic (Copenhagen, Denmark). PMID 26251007 DOI: 10.1111/Tra.12314  0.594
2015 Tomas A, Vaughan SO, Burgoyne T, Sorkin A, Hartley JA, Hochhauser D, Futter CE. WASH and Tsg101/ALIX-dependent diversion of stress-internalized EGFR from the canonical endocytic pathway. Nature Communications. 6: 7324. PMID 26066081 DOI: 10.1038/Ncomms8324  0.581
2015 Caltagarone J, Ma S, Sorkin A. Dopamine transporter is enriched in filopodia and induces filopodia formation. Molecular and Cellular Neurosciences. 68: 120-130. PMID 25936602 DOI: 10.1016/J.Mcn.2015.04.005  0.307
2015 Nagashima T, Inoue N, Yumoto N, Saeki Y, Magi S, Volinsky N, Sorkin A, Kholodenko BN, Okada-Hatakeyama M. Feedforward regulation of mRNA stability by prolonged extracellular signal-regulated kinase activity. The Febs Journal. 282: 613-29. PMID 25491268 DOI: 10.1111/Febs.13172  0.392
2015 Tomas A, Vaughan SO, Burgoyne T, Sorkin A, Hartley JA, Hochhauser D, Futter CE. WASH and Tsg101/ALIX-dependent diversion of stress-internalized EGFR from the canonical endocytic pathway Nature Communications. 6. DOI: 10.1038/ncomms8324  0.501
2014 Fortian A, Sorkin A. Live-cell fluorescence imaging reveals high stoichiometry of Grb2 binding to the EGF receptor sustained during endocytosis. Journal of Cell Science. 127: 432-44. PMID 24259669 DOI: 10.1242/Jcs.137786  0.624
2013 Huang F, Zeng X, Kim W, Balasubramani M, Fortian A, Gygi SP, Yates NA, Sorkin A. Lysine 63-linked polyubiquitination is required for EGF receptor degradation. Proceedings of the National Academy of Sciences of the United States of America. 110: 15722-7. PMID 24019463 DOI: 10.1073/Pnas.1308014110  0.603
2013 Goh LK, Sorkin A. Endocytosis of receptor tyrosine kinases. Cold Spring Harbor Perspectives in Biology. 5: a017459. PMID 23637288 DOI: 10.1101/Cshperspect.A017459  0.787
2013 Sorkina T, Caltagarone J, Sorkin A. Flotillins regulate membrane mobility of the dopamine transporter but are not required for its protein kinase C dependent endocytosis. Traffic (Copenhagen, Denmark). 14: 709-24. PMID 23418867 DOI: 10.1111/Tra.12059  0.44
2012 Galperin E, Abdelmoti L, Sorkin A. Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells. Plos One. 7: e36469. PMID 22606262 DOI: 10.1371/Journal.Pone.0036469  0.538
2012 Eden ER, Burgoyne T, Edgar JR, Sorkin A, Futter CE. The relationship between ER-multivesicular body membrane contacts and the ESCRT machinery. Biochemical Society Transactions. 40: 464-8. PMID 22435831 DOI: 10.1042/Bst20110774  0.598
2012 Rao A, Richards TL, Simmons D, Zahniser NR, Sorkin A. Epitope-tagged dopamine transporter knock-in mice reveal rapid endocytic trafficking and filopodia targeting of the transporter in dopaminergic axons. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1921-33. PMID 22267337 DOI: 10.1096/Fj.11-196113  0.313
2012 Eden ER, Huang F, Sorkin A, Futter CE. The role of EGF receptor ubiquitination in regulating its intracellular traffic. Traffic (Copenhagen, Denmark). 13: 329-37. PMID 22017370 DOI: 10.1111/J.1600-0854.2011.01305.X  0.635
2011 Duex JE, Comeau L, Sorkin A, Purow B, Kefas B. Usp18 regulates epidermal growth factor (EGF) receptor expression and cancer cell survival via microRNA-7. The Journal of Biological Chemistry. 286: 25377-86. PMID 21592959 DOI: 10.1074/Jbc.M111.222760  0.375
2011 Vina-Vilaseca A, Bender-Sigel J, Sorkina T, Closs EI, Sorkin A. Protein kinase C-dependent ubiquitination and clathrin-mediated endocytosis of the cationic amino acid transporter CAT-1. The Journal of Biological Chemistry. 286: 8697-706. PMID 21212261 DOI: 10.1074/Jbc.M110.186858  0.428
2011 Rao A, Simmons D, Sorkin A. Differential subcellular distribution of endosomal compartments and the dopamine transporter in dopaminergic neurons. Molecular and Cellular Neurosciences. 46: 148-58. PMID 20816972 DOI: 10.1016/J.Mcn.2010.08.016  0.303
2011 Duex JE, Kefas B, Purow B, Sorkin A. Abstract 4691: Inhibition of ubiquitin specific protease Usp18 reduces cancer cell proliferation by down regulating multiple proto-oncogenes including EGFR Cancer Research. 71: 4691-4691. DOI: 10.1158/1538-7445.Am2011-4691  0.487
2010 Goh LK, Huang F, Kim W, Gygi S, Sorkin A. Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor. The Journal of Cell Biology. 189: 871-83. PMID 20513767 DOI: 10.1083/Jcb.201001008  0.801
2010 Duex JE, Mullins MR, Sorkin A. Recruitment of Uev1B to Hrs-containing endosomes and its effect on endosomal trafficking. Experimental Cell Research. 316: 2136-51. PMID 20420830 DOI: 10.1016/J.Yexcr.2010.04.017  0.59
2010 Sorkin A, Duex JE. Quantitative analysis of endocytosis and turnover of epidermal growth factor (EGF) and EGF receptor. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 15.14. PMID 20235100 DOI: 10.1002/0471143030.Cb1514S46  0.595
2010 Vina-Vilaseca A, Sorkin A. Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes. The Journal of Biological Chemistry. 285: 7645-56. PMID 20051513 DOI: 10.1074/Jbc.M109.058990  0.387
2009 Sorkin A, von Zastrow M. Endocytosis and signalling: intertwining molecular networks. Nature Reviews. Molecular Cell Biology. 10: 609-22. PMID 19696798 DOI: 10.1038/Nrm2748  0.493
2009 Price DA, Sorkin A, Zahniser NR. Cyclin-dependent kinase 5 inhibitors: inhibition of dopamine transporter activity. Molecular Pharmacology. 76: 812-23. PMID 19628755 DOI: 10.1124/Mol.109.056978  0.347
2009 Zahniser NR, Sorkin A. Trafficking of dopamine transporters in psychostimulant actions. Seminars in Cell & Developmental Biology. 20: 411-7. PMID 19560046 DOI: 10.1016/J.Semcdb.2009.01.004  0.305
2009 Sorkin A, Goh LK. Endocytosis and intracellular trafficking of ErbBs. Experimental Cell Research. 315: 683-96. PMID 19278030 DOI: 10.1016/J.Yexcr.2008.07.029  0.805
2009 Sorkina T, Richards TL, Rao A, Zahniser NR, Sorkin A. Negative regulation of dopamine transporter endocytosis by membrane-proximal N-terminal residues. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1361-74. PMID 19193883 DOI: 10.1523/Jneurosci.3250-08.2009  0.382
2009 Duex JE, Sorkin A. RNA interference screen identifies Usp18 as a regulator of epidermal growth factor receptor synthesis. Molecular Biology of the Cell. 20: 1833-44. PMID 19158387 DOI: 10.1091/Mbc.E08-08-0880  0.566
2008 Sorkin A, Goh LK. Endocytosis and intracellular trafficking of ErbBs. Experimental Cell Research. 314: 3093-106. PMID 18793634 DOI: 10.1016/j.yexcr.2008.08.013  0.809
2008 Galperin E, Sorkin A. Endosomal targeting of MEK2 requires RAF, MEK kinase activity and clathrin-dependent endocytosis. Traffic (Copenhagen, Denmark). 9: 1776-90. PMID 18657070 DOI: 10.1111/J.1600-0854.2008.00788.X  0.555
2007 Huang F, Goh LK, Sorkin A. EGF receptor ubiquitination is not necessary for its internalization. Proceedings of the National Academy of Sciences of the United States of America. 104: 16904-9. PMID 17940017 DOI: 10.1073/Pnas.0707416104  0.798
2007 von Zastrow M, Sorkin A. Signaling on the endocytic pathway. Current Opinion in Cell Biology. 19: 436-45. PMID 17662591 DOI: 10.1016/J.Ceb.2007.04.021  0.383
2007 Miranda M, Sorkin A. Regulation of receptors and transporters by ubiquitination: new insights into surprisingly similar mechanisms. Molecular Interventions. 7: 157-67. PMID 17609522 DOI: 10.1124/Mi.7.3.7  0.512
2007 Miranda M, Dionne KR, Sorkina T, Sorkin A. Three ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporter. Molecular Biology of the Cell. 18: 313-23. PMID 17079728 DOI: 10.1091/Mbc.E06-08-0704  0.43
2006 Sorkina T, Miranda M, Dionne KR, Hoover BR, Zahniser NR, Sorkin A. RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8195-205. PMID 16885233 DOI: 10.1523/Jneurosci.1301-06.2006  0.414
2006 Huang F, Kirkpatrick D, Jiang X, Gygi S, Sorkin A. Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain. Molecular Cell. 21: 737-48. PMID 16543144 DOI: 10.1016/J.Molcel.2006.02.018  0.635
2005 Galperin E, Sorkin A. Visualization of Rab5 activity in living cells using FRET microscopy. Methods in Enzymology. 403: 119-34. PMID 16473582 DOI: 10.1016/S0076-6879(05)03011-9  0.311
2005 Miranda M, Wu CC, Sorkina T, Korstjens DR, Sorkin A. Enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase C. The Journal of Biological Chemistry. 280: 35617-24. PMID 16109712 DOI: 10.1074/Jbc.M506618200  0.425
2005 Sorkin A. TRKing signals through the Golgi. Science's Stke : Signal Transduction Knowledge Environment. 2005: pe1. PMID 15657262 DOI: 10.1126/Stke.2672005Pe1  0.564
2005 Huang F, Sorkin A. Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis. Molecular Biology of the Cell. 16: 1268-81. PMID 15635092 DOI: 10.1091/Mbc.E04-09-0832  0.593
2005 Sorkina T, Hoover BR, Zahniser NR, Sorkin A. Constitutive and protein kinase C-induced internalization of the dopamine transporter is mediated by a clathrin-dependent mechanism. Traffic (Copenhagen, Denmark). 6: 157-70. PMID 15634215 DOI: 10.1111/J.1600-0854.2005.00259.X  0.463
2004 Galperin E, Verkhusha VV, Sorkin A. Three-chromophore FRET microscopy to analyze multiprotein interactions in living cells. Nature Methods. 1: 209-17. PMID 15782196 DOI: 10.1038/Nmeth720  0.322
2004 Grøvdal LM, Stang E, Sorkin A, Madshus IH. Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation. Experimental Cell Research. 300: 388-95. PMID 15475003 DOI: 10.1016/J.Yexcr.2004.07.003  0.58
2004 Lladó A, Tebar F, Calvo M, Moretó J, Sorkin A, Enrich C. Protein kinaseCdelta-calmodulin crosstalk regulates epidermal growth factor receptor exit from early endosomes. Molecular Biology of the Cell. 15: 4877-91. PMID 15342779 DOI: 10.1091/Mbc.E04-02-0127  0.61
2004 Sorkin A. Cargo recognition during clathrin-mediated endocytosis: a team effort. Current Opinion in Cell Biology. 16: 392-9. PMID 15261671 DOI: 10.1016/J.Ceb.2004.06.001  0.437
2004 Miranda M, Sorkina T, Grammatopoulos TN, Zawada WM, Sorkin A. Multiple molecular determinants in the carboxyl terminus regulate dopamine transporter export from endoplasmic reticulum. The Journal of Biological Chemistry. 279: 30760-70. PMID 15128747 DOI: 10.1074/Jbc.M312774200  0.34
2004 Huang F, Khvorova A, Marshall W, Sorkin A. Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference. The Journal of Biological Chemistry. 279: 16657-61. PMID 14985334 DOI: 10.1074/Jbc.C400046200  0.56
2003 Galperin E, Sorkin A. Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma-membrane-targeted Rab5 on clathrin-dependent endocytosis. Journal of Cell Science. 116: 4799-810. PMID 14600265 DOI: 10.1242/Jcs.00801  0.417
2003 Huang F, Jiang X, Sorkin A. Tyrosine phosphorylation of the beta2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the epidermal growth factor receptor trafficking. The Journal of Biological Chemistry. 278: 43411-7. PMID 12900408 DOI: 10.1074/Jbc.M306072200  0.543
2003 Jiang X, Sorkin A. Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation. Traffic (Copenhagen, Denmark). 4: 529-43. PMID 12839496 DOI: 10.1034/J.1600-0854.2003.T01-1-00109.X  0.565
2003 Sorkina T, Doolen S, Galperin E, Zahniser NR, Sorkin A. Oligomerization of dopamine transporters visualized in living cells by fluorescence resonance energy transfer microscopy. The Journal of Biological Chemistry. 278: 28274-83. PMID 12746456 DOI: 10.1074/Jbc.M210652200  0.368
2003 Jiang X, Huang F, Marusyk A, Sorkin A. Grb2 regulates internalization of EGF receptors through clathrin-coated pits. Molecular Biology of the Cell. 14: 858-70. PMID 12631709 DOI: 10.1091/Mbc.E02-08-0532  0.644
2002 Sorkin A, Von Zastrow M. Signal transduction and endocytosis: close encounters of many kinds. Nature Reviews. Molecular Cell Biology. 3: 600-14. PMID 12154371 DOI: 10.1038/Nrm883  0.517
2002 Tebar F, Villalonga P, Sorkina T, Agell N, Sorkin A, Enrich C. Calmodulin regulates intracellular trafficking of epidermal growth factor receptor and the MAPK signaling pathway. Molecular Biology of the Cell. 13: 2057-68. PMID 12058069 DOI: 10.1091/Mbc.01-12-0571  0.647
2002 Sorkina T, Huang F, Beguinot L, Sorkin A. Effect of tyrosine kinase inhibitors on clathrin-coated pit recruitment and internalization of epidermal growth factor receptor. The Journal of Biological Chemistry. 277: 27433-41. PMID 12021271 DOI: 10.1074/Jbc.M201595200  0.611
2002 Jiang X, Sorkin A. Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells. Molecular Biology of the Cell. 13: 1522-35. PMID 12006650 DOI: 10.1091/Mbc.01-11-0552  0.369
2001 Sorkin A. Internalization of the epidermal growth factor receptor: role in signalling Biochemical Society Transactions. 29: 480-484. PMID 11498013 DOI: 10.1042/Bst0290480  0.635
2001 Huang F, Nesterov A, Carter RE, Sorkin A. Trafficking of yellow-fluorescent-protein-tagged mu1 subunit of clathrin adaptor AP-1 complex in living cells. Traffic. 2: 345-357. PMID 11350630 DOI: 10.1034/J.1600-0854.2001.25020506.X  0.388
2001 Gu C, Sorkin A, Cooper DMF. Persistent interactions between the two transmembrane clusters dictate the targeting and functional assembly of adenylyl cyclase Current Biology. 11: 185-190. PMID 11231154 DOI: 10.1016/S0960-9822(01)00044-6  0.35
2001 Sorkin A, McClure M, Huang F, Carter R. Interaction of EGF receptor and grb2 in living cells visualized by fluorescence resonance energy transfer (FRET) microscopy. Current Biology : Cb. 10: 1395-8. PMID 11084343 DOI: 10.1016/S0960-9822(00)00785-5  0.599
1999 Tebar F, Bohlander SK, Sorkin A. Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic. Molecular Biology of the Cell. 10: 2687-702. PMID 10436022 DOI: 10.1091/Mbc.10.8.2687  0.443
1999 Nesterov A, Carter RE, Sorkina T, Gill GN, Sorkin A. Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant μ2 subunit and its effects on endocytosis The Embo Journal. 18: 2489-2499. PMID 10228163 DOI: 10.1093/Emboj/18.9.2489  0.539
1998 Carter RE, Sorkin A. Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera Journal of Biological Chemistry. 273: 35000-35007. PMID 9857032 DOI: 10.1074/Jbc.273.52.35000  0.646
1998 de Beer T, Carter RE, Lobel-Rice KE, Sorkin A, Overduin M. Structure and Asn-Pro-Phe binding pocket of the Eps15 homology domain. Science (New York, N.Y.). 281: 1357-60. PMID 9721102 DOI: 10.1126/Science.281.5381.1357  0.32
1998 Coda L, Salcini AE, Confalonieri S, Pelicci G, Sorkina T, Sorkin A, Pelicci PG, Di Fiore PP. Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization. The Journal of Biological Chemistry. 273: 3003-12. PMID 9446614 DOI: 10.1074/Jbc.273.5.3003  0.528
1997 Fiore PPD, Pelicci PG, Sorkin A. EH: a novel protein-protein interaction domain potentially involved in intracellular sorting Trends in Biochemical Sciences. 22: 411-413. PMID 9397678 DOI: 10.1016/S0968-0004(97)01127-4  0.315
1997 Tebar F, Confalonieri S, Carter RE, Di Fiore PP, Sorkin A. Eps15 is constitutively oligomerized due to homophilic interaction of its coiled-coil region. The Journal of Biological Chemistry. 272: 15413-8. PMID 9182572 DOI: 10.1074/Jbc.272.24.15413  0.361
1997 Kornilova E, Sorkina T, Beguinot L, Sorkin A. Lysosomal targeting of epidermal growth factor receptors via a kinase-dependent pathway is mediated by the receptor carboxyl-terminal residues 1022-1123. The Journal of Biological Chemistry. 271: 30340-6. PMID 8939994 DOI: 10.1074/Jbc.271.48.30340  0.607
1996 Tebar F, Sorkina T, Sorkin A, Ericsson M, Kirchhausen T. Eps15 is a component of clathrin-coated pits and vesicles and is located at the rim of coated pits Journal of Biological Chemistry. 271: 28727-28730. PMID 8910509 DOI: 10.1074/Jbc.271.46.28727  0.422
1996 Sorkin A, Mazzotti M, Sorkina T, Scotto L, Beguinot L. Epidermal growth factor receptor interaction with clathrin adaptors is mediated by the Tyr974-containing internalization motif. The Journal of Biological Chemistry. 271: 13377-84. PMID 8662849 DOI: 10.1074/Jbc.271.23.13377  0.556
1995 Sorkin A, McKinsey T, Shih W, Kirchhausen T, Carpenter G. Stoichiometric interaction of the epidermal growth factor receptor with the clathrin-associated protein complex AP-2 Journal of Biological Chemistry. 270: 619-625. PMID 7822287 DOI: 10.1074/Jbc.270.2.619  0.526
1995 Carpenter G, Soler C, Baulida J, Beguinot L, Sorkin A. Interaction of signaling and trafficking proteins with the carboxyterminus of the epidermal growth factor receptor. Annals of the New York Academy of Sciences. 766: 44-51. PMID 7486689 DOI: 10.1111/J.1749-6632.1995.Tb26647.X  0.51
1993 Sorkin A, Waters CM. Endocytosis of growth factor receptors. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 15: 375-82. PMID 8395172 DOI: 10.1002/Bies.950150603  0.556
1993 Sorkin A, Carpenter G. Interaction of activated EGF receptors with coated pit adaptins. Science (New York, N.Y.). 261: 612-5. PMID 8342026 DOI: 10.1126/Science.8342026  0.529
1993 Sorkin A, Eriksson A, Heldin CH, Westermark B, Claesson-Welsh L. Pool of ligand-bound platelet-derived growth factor beta-receptors remain activated and tyrosine phosphorylated after internalization. Journal of Cellular Physiology. 156: 373-82. PMID 7688373 DOI: 10.1002/Jcp.1041560221  0.528
1992 Waters CM, Overholser KA, Sorkin A, Carpenter G. Analysis of the influences of the E5 transforming protein on kinetic parameters of epidermal growth factor binding and metabolism Journal of Cellular Physiology. 152: 253-263. PMID 1639860 DOI: 10.1002/Jcp.1041520206  0.45
1991 Sorkin A, Krolenko S, Kudrjavtceva N, Lazebnik J, Teslenko L, Soderquist AM, Nikolsky N. Recycling of epidermal growth factor-receptor complexes in A431 cells: identification of dual pathways Journal of Cell Biology. 112: 55-63. PMID 1986007 DOI: 10.1083/Jcb.112.1.55  0.408
1991 Sorkin A, Westermark B, Heldin CH, Claesson-Welsh L. Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor. Journal of Cell Biology. 112: 469-478. PMID 1846866 DOI: 10.1083/Jcb.112.3.469  0.52
1989 Sorkin A, Kornilova E, Teslenko L, Sorokin A, Nikolsky N. Recycling of epidermal growth factor-receptor complexes in A431 cells. Biochimica Et Biophysica Acta. 1011: 88-96. PMID 2784329 DOI: 10.1016/0167-4889(89)90083-9  0.518
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