| Year |
Citation |
Score |
| 2015 |
Spink BC, Bloom MS, Wu S, Sell S, Schneider E, Ding X, Spink DC. Analysis of the AHR gene proximal promoter GGGGC-repeat polymorphism in lung, breast, and colon cancer. Toxicology and Applied Pharmacology. 282: 30-41. PMID 25447411 DOI: 10.1016/J.Taap.2014.10.017 |
0.423 |
|
| 2013 |
Spink BC, Bennett JA, Lostritto N, Cole JR, Spink DC. Expression of the aryl hydrocarbon receptor is not required for the proliferation, migration, invasion, or estrogen-dependent tumorigenesis of MCF-7 breast cancer cells. Molecular Carcinogenesis. 52: 544-54. PMID 22388733 DOI: 10.1002/Mc.21889 |
0.586 |
|
| 2012 |
Englert NA, Turesky RJ, Han W, Bessette EE, Spivack SD, Caggana M, Spink DC, Spink BC. Genetic and epigenetic regulation of AHR gene expression in MCF-7 breast cancer cells: role of the proximal promoter GC-rich region. Biochemical Pharmacology. 84: 722-35. PMID 22728919 DOI: 10.1016/J.Bcp.2012.06.013 |
0.711 |
|
| 2011 |
Englert NA, Spink BC, Spink DC. Persistent and non-persistent changes in gene expression result from long-term estrogen exposure of MCF-7 breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 123: 140-50. PMID 21185374 DOI: 10.1016/J.Jsbmb.2010.12.010 |
0.727 |
|
| 2009 |
Spink BC, Bennett JA, Pentecost BT, Lostritto N, Englert NA, Benn GK, Goodenough AK, Turesky RJ, Spink DC. Long-term estrogen exposure promotes carcinogen bioactivation, induces persistent changes in gene expression, and enhances the tumorigenicity of MCF-7 human breast cancer cells. Toxicology and Applied Pharmacology. 240: 355-66. PMID 19619570 DOI: 10.1016/J.Taap.2009.07.013 |
0.749 |
|
| 2008 |
Spink DC, Wu SJ, Spink BC, Hussain MM, Vakharia DD, Pentecost BT, Kaminsky LS. Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites. Toxicology and Applied Pharmacology. 226: 213-24. PMID 17919675 DOI: 10.1016/j.taap.2007.08.024 |
0.366 |
|
| 2006 |
Spink BC, Cole RW, Katz BH, Gierthy JF, Bradley LM, Spink DC. Inhibition of MCF-7 breast cancer cell proliferation by MCF-10A breast epithelial cells in coculture. Cell Biology International. 30: 227-38. PMID 16427788 DOI: 10.1016/J.Cellbi.2005.11.006 |
0.402 |
|
| 2004 |
Oenga GN, Spink DC, Carpenter DO. TCDD and PCBs inhibit breast cancer cell proliferation in vitro. Toxicology in Vitro : An International Journal Published in Association With Bibra. 18: 811-9. PMID 15465647 DOI: 10.1016/J.Tiv.2004.04.004 |
0.598 |
|
| 2003 |
Spink BC, Hussain MM, Katz BH, Eisele L, Spink DC. Transient induction of cytochromes P450 1A1 and 1B1 in MCF-7 human breast cancer cells by indirubin. Biochemical Pharmacology. 66: 2313-21. PMID 14637189 DOI: 10.1016/j.bcp.2003.08.019 |
0.43 |
|
| 2003 |
Spink DC, Katz BH, Hussain MM, Pentecost BT, Cao Z, Spink BC. Estrogen regulates Ah responsiveness in MCF-7 breast cancer cells. Carcinogenesis. 24: 1941-50. PMID 12970067 DOI: 10.1093/carcin/bgg162 |
0.514 |
|
| 2002 |
Spink BC, Pang S, Pentecost BT, Spink DC. Induction of cytochrome P450 1B1 in MDA-MB-231 human breast cancer cells by non-ortho-substituted polychlorinated biphenyls. Toxicology in Vitro : An International Journal Published in Association With Bibra. 16: 695-704. PMID 12423652 DOI: 10.1016/S0887-2333(02)00091-7 |
0.45 |
|
| 2002 |
Spink DC, Katz BH, Hussain MM, Spink BC, Wu SJ, Liu N, Pause R, Kaminsky LS. Induction of CYP1A1 and CYP1B1 in T-47D human breast cancer cells by benzo[a]pyrene is diminished by arsenite. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 262-9. PMID 11854143 DOI: 10.1124/dmd.30.3.262 |
0.374 |
|
| 2001 |
Spink DC, Zhang F, Hussain MM, Katz BH, Liu X, Hilker DR, Bolton JL. Metabolism of equilenin in MCF-7 and MDA-MB-231 human breast cancer cells. Chemical Research in Toxicology. 14: 572-81. PMID 11368557 DOI: 10.1021/Tx000219R |
0.333 |
|
| 2000 |
Spink DC, Spink BC, Zhuo X, Hussain MM, Gierthy JF, Ding X. NADPH- and hydroperoxide-supported 17beta-estradiol hydroxylation catalyzed by a variant form (432L, 453S) of human cytochrome P450 1B1. The Journal of Steroid Biochemistry and Molecular Biology. 74: 11-8. PMID 11074351 DOI: 10.1016/S0960-0760(00)00083-2 |
0.433 |
|
| 2000 |
Spink BC, Katz BH, Hussain MM, Pang S, Connor SP, Aldous KM, Gierthy JF, Spink DC. SULT1A1 catalyzes 2-methoxyestradiol sulfonation in MCF-7 breast cancer cells. Carcinogenesis. 21: 1947-57. PMID 11062153 DOI: 10.1093/Carcin/21.11.1947 |
0.548 |
|
| 1999 |
Gu J, Dudley C, Su T, Spink DC, Zhang QY, Moss RL, Ding X. Cytochrome P450 and steroid hydroxylase activity in mouse olfactory and vomeronasal mucosa. Biochemical and Biophysical Research Communications. 266: 262-7. PMID 10581200 DOI: 10.1006/Bbrc.1999.1807 |
0.302 |
|
| 1999 |
Pang S, Cao JQ, Katz BH, Hayes CL, Sutter TR, Spink DC. Inductive and inhibitory effects of non-ortho-substituted polychlorinated biphenyls on estrogen metabolism and human cytochromes P450 1A1 and 1B1. Biochemical Pharmacology. 58: 29-38. PMID 10403516 DOI: 10.1016/S0006-2952(99)00070-2 |
0.522 |
|
| 1999 |
Arcaro KF, Yi L, Seegal RF, Vakharia DD, Yang Y, Spink DC, Brosch K, Gierthy JF. 2,2′,6,6′-Tetrachlorobiphenyl is estrogenic in vitro and in vivo Journal of Cellular Biochemistry. 72: 94-102. PMID 10025670 DOI: 10.1002/(Sici)1097-4644(19990101)72:1<94::Aid-Jcb10>3.0.Co;2-Y |
0.434 |
|
| 1998 |
Spink BC, Fasco MJ, Gierthy JF, Spink DC. 12-O-tetradecanoylphorbol-13-acetate upregulates the Ah receptor and differentially alters CYP1B1 and CYP1A1 expression in MCF-7 breast cancer cells. Journal of Cellular Biochemistry. 70: 289-96. PMID 9706865 DOI: 10.1002/(Sici)1097-4644(19980901)70:3<289::Aid-Jcb1>3.0.Co;2-J |
0.475 |
|
| 1998 |
Spink DC, Spink BC, Cao JQ, DePasquale JA, Pentecost BT, Fasco MJ, Li Y, Sutter TR. Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells. Carcinogenesis. 19: 291-8. PMID 9498279 DOI: 10.1093/Carcin/19.2.291 |
0.494 |
|
| 1997 |
Spink DC, Spink BC, Cao JQ, Gierthy JF, Hayes CL, Li Y, Sutter TR. Induction of cytochrome P450 1B1 and catechol estrogen metabolism in ACHN human renal adenocarcinoma cells. The Journal of Steroid Biochemistry and Molecular Biology. 62: 223-32. PMID 9393958 DOI: 10.1016/S0960-0760(97)00024-1 |
0.446 |
|
| 1996 |
Hayes CL, Spink DC, Spink BC, Cao JQ, Walker NJ, Sutter TR. 17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1. Proceedings of the National Academy of Sciences of the United States of America. 93: 9776-81. PMID 8790407 DOI: 10.1073/Pnas.93.18.9776 |
0.452 |
|
| 1996 |
Gierthy JF, Spink BC, Figge HL, Pentecost BT, Spink DC. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin, 12-O-tetradecanoylphorbol-13-acetate and 17 beta-estradiol on estrogen receptor regulation in MCF-7 human breast cancer cells. Journal of Cellular Biochemistry. 60: 173-84. PMID 8655628 DOI: 10.1002/(Sici)1097-4644(19960201)60:2<173::Aid-Jcb2>3.0.Co;2-U |
0.448 |
|
| 1995 |
Zhu M, Spink DC, Yan B, Bank S, DeCaprio AP. Inhibition of 2,5-hexanedione-induced protein cross-linking by biological thiols: chemical mechanisms and toxicological implications. Chemical Research in Toxicology. 8: 764-71. PMID 7548760 DOI: 10.1021/Tx00047A017 |
0.301 |
|
| 1994 |
Christou M, Savas U, Spink DC, Gierthy JF, Jefcoate CR. Co-expression of human CYP1A1 and a human analog of cytochrome P450-EF in response to 2,3,7,8-tetrachloro-dibenzo-p-dioxin in the human mammary carcinoma-derived MCF-7 cells Carcinogenesis. 15: 725-732. PMID 8149487 DOI: 10.1093/Carcin/15.4.725 |
0.356 |
|
| 1994 |
Spink DC, Johnson JA, Connor SP, Aldous KM, Gierthy JF. Stimulation of 17 beta-estradiol metabolism in MCF-7 cells by bromochloro- and chloromethyl-substituted dibenzo-p-dioxins and dibenzofurans: correlations with antiestrogenic activity. Journal of Toxicology and Environmental Health. 41: 451-66. PMID 8145285 DOI: 10.1080/15287399409531856 |
0.377 |
|
| 1994 |
Spink DC, Hayes CL, Young NR, Christou M, Sutter TR, Jefcoate CR, Gierthy JF. The effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: Evidence for induction of a novel 17β-estradiol 4-hydroxylase Journal of Steroid Biochemistry and Molecular Biology. 51: 251-258. PMID 7826886 DOI: 10.1016/0960-0760(94)90037-X |
0.535 |
|
| 1992 |
Spink DC, Eugster HP, Lincoln DW, Schuetz JD, Schuetz EG, Johnson JA, Kaminsky LS, Gierthy JF. 17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1A1: a comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA. Archives of Biochemistry and Biophysics. 293: 342-8. PMID 1536570 DOI: 10.1016/0003-9861(92)90404-K |
0.361 |
|
| 1992 |
Spink DC, Lincoln DW, Johnson JA, Dickerman HW, Gierthy JF. Stimulation of 17ß-estradiol metabolism in MCF-7 breast cancer cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin Chemosphere. 25: 87-90. DOI: 10.1016/0045-6535(92)90486-B |
0.496 |
|
| 1990 |
Spink DC, Lincoln DW, Dickerman HW, Gierthy JF. 2,3,7,8-Tetrachlorodibenzo-p-dioxin causes an extensive alteration of 17 beta-estradiol metabolism in MCF-7 breast tumor cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 6917-21. PMID 2395886 DOI: 10.1073/Pnas.87.17.6917 |
0.385 |
|
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