| Year |
Citation |
Score |
| 2023 |
Wu C, Weis SM, Cheresh DA. Tumor-initiating cells establish a niche to overcome isolation stress. Trends in Cell Biology. PMID 37640611 DOI: 10.1016/j.tcb.2023.08.001 |
0.305 |
|
| 2019 |
Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, ... ... Cheresh DA, et al. Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αβ Axis. Cell Stem Cell. PMID 31956038 DOI: 10.1016/J.Stem.2019.11.016 |
0.35 |
|
| 2019 |
Wettersten HI, Weis SM, Pathria P, von Schalscha T, Minami T, Varner JA, Cheresh DA. Arming tumor-associated macrophages to reverse epithelial cancer progression. Cancer Research. PMID 31416839 DOI: 10.1158/0008-5472.Can-19-1246 |
0.437 |
|
| 2019 |
Carlson P, Dasgupta A, Grzelak CA, Kim J, Barrett A, Coleman IM, Shor RE, Goddard ET, Dai J, Schweitzer EM, Lim AR, Crist SB, Cheresh DA, Nelson PS, Hansen KC, et al. Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy. Nature Cell Biology. PMID 30664790 DOI: 10.1038/S41556-018-0267-0 |
0.374 |
|
| 2019 |
Pathria P, Takahashi H, Kaneda M, Pu M, Messer K, Shepard RM, Louis TL, Shih A, Bertagnolli M, Wrasidlo W, Cheresh DA, Varner JA. Abstract 113: c-Kit-dependent tissue resident macrophage progenitors drive cancer progression Cancer Research. 78: 5006-5006. DOI: 10.1158/1538-7445.Am2018-5006 |
0.404 |
|
| 2018 |
Schmid MC, Khan SQ, Kaneda MM, Pathria P, Shepard R, Louis TL, Anand S, Woo G, Leem C, Faridi MH, Geraghty T, Rajagopalan A, Gupta S, Ahmed M, Vazquez-Padron RI, ... Cheresh DA, et al. Integrin CD11b activation drives anti-tumor innate immunity. Nature Communications. 9: 5379. PMID 30568188 DOI: 10.1038/S41467-018-07387-4 |
0.446 |
|
| 2018 |
Wang H, Lapek J, Fujimura K, Strnadel J, Liu B, Gonzalez DJ, Zhang W, Watson F, Yu V, Liu C, Melo CM, Miller YI, Elliott KC, Cheresh DA, Klemke RL. Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription. Cell Discovery. 4: 26. PMID 29872538 DOI: 10.1038/S41421-018-0024-3 |
0.695 |
|
| 2018 |
Sun Q, Lesperance J, Wettersten H, Luterstein E, DeRose YS, Welm A, Cheresh DA, Desgrosellier JS. Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis. The Journal of Clinical Investigation. 128: 531-544. PMID 29227280 DOI: 10.1172/Jci93707 |
0.449 |
|
| 2018 |
Rakhshandehroo T, Tan J, Grosshart B, Cheresh D. Abstract LB-049: Cancer stem cell-produced lysophosphatidic acid reprograms surrounding tumor cells to a stem-like state Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-049 |
0.371 |
|
| 2017 |
Cosset É, Ilmjärv S, Dutoit V, Elliott K, von Schalscha T, Camargo MF, Reiss A, Moroishi T, Seguin L, Gomez G, Moo JS, Preynat-Seauve O, Krause KH, Chneiweiss H, Sarkaria JN, ... ... Cheresh DA, et al. Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma. Cancer Cell. 32: 856-868.e5. PMID 29198914 DOI: 10.1016/J.Ccell.2017.10.016 |
0.398 |
|
| 2017 |
Seguin L, Camargo MF, Wettersten HI, Kato S, Desgrosellier JS, von Schalscha T, Elliott KC, Cosset E, Lesperance J, Weis SM, Cheresh DA. Galectin-3, a druggable vulnerability for KRAS-addicted cancers. Cancer Discovery. PMID 28893801 DOI: 10.1158/2159-8290.Cd-17-0539 |
0.407 |
|
| 2017 |
Hazell AS, Afadlal S, Cheresh D, Azar A. TREATMENT OF RATS WITH THE JAK-2 INHIBITOR FEDRATINIB DOES NOT LEAD TO EXPERIMENTAL WERNICKE's ENCEPHALOPATHY. Neuroscience Letters. PMID 28109775 DOI: 10.1016/J.Neulet.2017.01.041 |
0.302 |
|
| 2017 |
Wettersten HI, Minami T, Kaneda MM, Seguin L, Varner JA, Weis SM, Cheresh DA. Abstract 3966: Targeting integrin αvβ3-expressing cancer stem cells to manipulate tumor-associated macrophages Cancer Research. 77: 3966-3966. DOI: 10.1158/1538-7445.Am2017-3966 |
0.396 |
|
| 2017 |
Seguin L, Camargo MF, Wettersten HI, Kato S, Schalscha Tv, Elliott KC, Weis SM, Cheresh DA. Abstract 3067: Galectin-3, a target for KRAS-addicted lung cancer Cancer Research. 77: 3067-3067. DOI: 10.1158/1538-7445.Am2017-3067 |
0.36 |
|
| 2016 |
Wilson R, Espinosa-Diez C, Kanner N, Chatterjee N, Ruhl R, Hipfinger C, Advani SJ, Li J, Khan OF, Franovic A, Weis SM, Kumar S, Coussens LM, Anderson DG, Chen CC, ... Cheresh DA, et al. MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment. Nature Communications. 7: 13597. PMID 27886180 DOI: 10.1038/Ncomms13597 |
0.352 |
|
| 2015 |
Advani SJ, Camargo MF, Seguin L, Mielgo A, Anand S, Hicks AM, Aguilera J, Franovic A, Weis SM, Cheresh DA. Kinase-independent role for CRAF-driving tumour radioresistance via CHK2. Nature Communications. 6: 8154. PMID 26333361 DOI: 10.1038/Ncomms9154 |
0.343 |
|
| 2015 |
Franovic A, Elliott KC, Seguin L, Camargo MF, Weis SM, Cheresh DA. Glioblastomas Require Integrin αvβ3/PAK4 Signaling to Escape Senescence. Cancer Research. 75: 4466-73. PMID 26297735 DOI: 10.1158/0008-5472.Can-15-0988 |
0.46 |
|
| 2015 |
Acevedo LM, Lindquist JN, Walsh BM, Sia P, Cimadamore F, Chen C, Denzel M, Pernia CD, Ranscht B, Terskikh A, Snyder EY, Cheresh DA. hESC Differentiation toward an Autonomic Neuronal Cell Fate Depends on Distinct Cues from the Co-Patterning Vasculature. Stem Cell Reports. 4: 1075-88. PMID 26004631 DOI: 10.1016/J.Stemcr.2015.04.013 |
0.335 |
|
| 2015 |
Seguin L, Desgrosellier JS, Weis SM, Cheresh DA. Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance. Trends in Cell Biology. 25: 234-40. PMID 25572304 DOI: 10.1016/J.Tcb.2014.12.006 |
0.448 |
|
| 2015 |
Jean C, Chen XL, Tancioni I, Uryu S, Lawson C, Miller N, Turowski P, Dejana E, Weis S, Cheresh D, Schlaepfer DD. Abstract A04: Endothelial FAK activity controls vascular permeability and tumor metastasis Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-A04 |
0.499 |
|
| 2014 |
Desgrosellier JS, Lesperance J, Seguin L, Gozo M, Kato S, Franovic A, Yebra M, Shattil SJ, Cheresh DA. Integrin αvβ3 drives slug activation and stemness in the pregnant and neoplastic mammary gland. Developmental Cell. 30: 295-308. PMID 25117682 DOI: 10.1016/J.Devcel.2014.06.005 |
0.372 |
|
| 2014 |
Seguin L, Gozo M, Weis SM, Cheresh DA. Targeting the Achilles' heel of drug-resistant cancer stem cells. Cell Cycle (Georgetown, Tex.). 13: 2017-8. PMID 24906000 DOI: 10.4161/Cc.29460 |
0.444 |
|
| 2014 |
Seguin L, Weis SM, Cheresh DA. Variety in the tumor microenvironment: integrin splicing regulates stemness. Cell Stem Cell. 14: 557-8. PMID 24792112 DOI: 10.1016/J.Stem.2014.04.011 |
0.418 |
|
| 2014 |
Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, ... ... Cheresh DA, et al. An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. Nature Cell Biology. 16: 457-68. PMID 24747441 DOI: 10.1038/Ncb2953 |
0.353 |
|
| 2014 |
Jean C, Chen XL, Nam JO, Tancioni I, Uryu S, Lawson C, Ward KK, Walsh CT, Miller NL, Ghassemian M, Turowski P, Dejana E, Weis S, Cheresh DA, Schlaepfer DD. Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function. The Journal of Cell Biology. 204: 247-63. PMID 24446483 DOI: 10.1083/Jcb.201307067 |
0.491 |
|
| 2014 |
Cheresh DA, Stupack DG. Tumor angiogenesis: putting a value on plastic GEMMs. Circulation Research. 114: 9-11. PMID 24385501 DOI: 10.1161/Circresaha.113.302812 |
0.444 |
|
| 2014 |
Kato S, Seguin L, Franovic A, Kato H, Camargo M, Desgrosellier J, Anand S, Weis S, Shattil S, Cheresh DA. Abstract 4240: Targeting Galectin-3 to reverse tumor stemness and drug resistance Cancer Research. 74: 4240-4240. DOI: 10.1158/1538-7445.Am2014-4240 |
0.394 |
|
| 2014 |
Desgrosellier JS, Lesperance J, Seguin L, Shattil SJ, Cheresh DA. Abstract 3034: Integrin αvβ3 drives Slug activation and stemness in the pregnant and neoplastic mammary gland Cancer Research. 74: 3034-3034. DOI: 10.1158/1538-7445.Am2014-3034 |
0.347 |
|
| 2014 |
Seguin LJ, Kato S, Franovic A, Camargo MF, Elliott K, Yebra M, Lesperance J, Mielgo A, Desgrosellier J, Anand S, Weis S, Cheresh D. Abstract 1916: β3 integrin/KRAS/RalB complex drives tumor stemness and resistance to EGFR inhibition Cancer Research. 74: 1916-1916. DOI: 10.1158/1538-7445.Am2014-1916 |
0.428 |
|
| 2014 |
Anand S, Advani SJ, Cheresh DA. Abstract 18: MicroRNA-103 induces DNA damage and radiosensitizes the tumor vasculature Cancer Research. 74: 18-18. DOI: 10.1158/1538-7445.Am2014-18 |
0.348 |
|
| 2013 |
Han J, Zhang G, Welch EJ, Liang Y, Fu J, Vogel SM, Lowell CA, Du X, Cheresh DA, Malik AB, Li Z. A critical role for Lyn kinase in strengthening endothelial integrity and barrier function. Blood. 122: 4140-9. PMID 24108461 DOI: 10.1182/Blood-2013-03-491423 |
0.372 |
|
| 2013 |
Westenskow PD, Kurihara T, Aguilar E, Scheppke EL, Moreno SK, Wittgrove C, Marchetti V, Michael IP, Anand S, Nagy A, Cheresh D, Friedlander M. Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting. The Journal of Clinical Investigation. 123: 4900-8. PMID 24084735 DOI: 10.1172/Jci70230 |
0.358 |
|
| 2013 |
Weis SM, Cheresh DA. A wake-up call for hibernating tumour cells. Nature Cell Biology. 15: 721-3. PMID 23817234 DOI: 10.1038/Ncb2794 |
0.357 |
|
| 2013 |
Garmy-Susini B, Avraamides CJ, Desgrosellier JS, Schmid MC, Foubert P, Ellies LG, Lowy AM, Blair SL, Vandenberg SR, Datnow B, Wang HY, Cheresh DA, Varner J. PI3Kα activates integrin α4β1 to establish a metastatic niche in lymph nodes. Proceedings of the National Academy of Sciences of the United States of America. 110: 9042-7. PMID 23671068 DOI: 10.1073/Pnas.1219603110 |
0.336 |
|
| 2013 |
Desgrosellier J, Lesperance J, Seguin L, Shattil S, Cheresh D. Abstract A036: Integrin αvβ3 drives the mammary stem cell state during pregnancy Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-A036 |
0.348 |
|
| 2013 |
Desgrosellier J, Lesperance J, Seguin L, Cheresh D. Abstract C78: Integrin αvβ3 drives stemness in the pregnant and neoplastic mammary gland Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-C78 |
0.369 |
|
| 2013 |
Jean C, Nam J, Chen X, Uryu S, Tancioni I, Lawson C, Ward KK, Walsh CT, Ghassemian M, Turowski P, Dejana E, Weis SM, Cheresh DA, Schlaepfer DD. Abstract B39: Inhibiting endothelial FAK activity blocks tumor cell extravasation Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-B39 |
0.534 |
|
| 2012 |
Sicklick JK, Leonard SY, Mose E, French RP, Criscuoli M, Jaquish DV, Maruyama K, Schwab RB, Cheresh D, Lowy AM. A novel xenograft model of gastrointestinal stromal tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 202. PMID 27983169 DOI: 10.1200/Jco.2012.30.4_Suppl.202 |
0.346 |
|
| 2012 |
Lu KV, Chang JP, Parachoniak CA, Pandika MM, Aghi MK, Meyronet D, Isachenko N, Fouse SD, Phillips JJ, Cheresh DA, Park M, Bergers G. VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex. Cancer Cell. 22: 21-35. PMID 22789536 DOI: 10.1016/J.Ccr.2012.05.037 |
0.478 |
|
| 2012 |
Lim ST, Miller NL, Chen XL, Tancioni I, Walsh CT, Lawson C, Uryu S, Weis SM, Cheresh DA, Schlaepfer DD. Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression. The Journal of Cell Biology. 197: 907-19. PMID 22734001 DOI: 10.1083/Jcb.201109067 |
0.416 |
|
| 2012 |
Lau SK, Shields DJ, Murphy EA, Desgrosellier JS, Anand S, Huang M, Kato S, Lim ST, Weis SM, Stupack DG, Schlaepfer DD, Cheresh DA. EGFR-mediated carcinoma cell metastasis mediated by integrin αvβ5 depends on activation of c-Src and cleavage of MUC1. Plos One. 7: e36753. PMID 22586492 DOI: 10.1371/Journal.Pone.0036753 |
0.806 |
|
| 2012 |
Yu PT, Babicky M, Jaquish D, French R, Marayuma K, Mose E, Niessen S, Hoover H, Shields D, Cheresh D, Cravatt BF, Lowy AM. The RON-receptor regulates pancreatic cancer cell migration through phosphorylation-dependent breakdown of the hemidesmosome. International Journal of Cancer. Journal International Du Cancer. 131: 1744-54. PMID 22275185 DOI: 10.1002/Ijc.27447 |
0.433 |
|
| 2012 |
Chen XL, Nam JO, Jean C, Lawson C, Walsh CT, Goka E, Lim ST, Tomar A, Tancioni I, Uryu S, Guan JL, Acevedo LM, Weis SM, Cheresh DA, Schlaepfer DD. VEGF-induced vascular permeability is mediated by FAK. Developmental Cell. 22: 146-57. PMID 22264731 DOI: 10.1016/J.Devcel.2011.11.002 |
0.441 |
|
| 2012 |
Scheppke L, Murphy EA, Zarpellon A, Hofmann JJ, Merkulova A, Shields DJ, Weis SM, Byzova TV, Ruggeri ZM, Iruela-Arispe ML, Cheresh DA. Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane. Blood. 119: 2149-58. PMID 22134168 DOI: 10.1182/Blood-2011-04-348706 |
0.384 |
|
| 2012 |
Huang M, Anand S, Murphy EA, Desgrosellier JS, Stupack DG, Shattil SJ, Schlaepfer DD, Cheresh DA. EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation. Oncogene. 31: 2783-93. PMID 21963850 DOI: 10.1038/Onc.2011.450 |
0.783 |
|
| 2012 |
Franovic A, Cheresh DA. Abstract LB-493: Blocking the integrin αvβ3-CRAF axis with Cilengitide arrests glioblastoma cells in pro-metaphase Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-493 |
0.506 |
|
| 2012 |
Seguin LJ, Mielgo A, Huang M, Camargo FC, Lesperance J, Weis SM, Desgrosellier JS, Cheresh DA. Abstract LB-344: Emergence of carcinoma resistance to EGFR blockade via an integrin avb3/RalB/NFkB signaling axis Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-344 |
0.435 |
|
| 2011 |
Reardon DA, Cheresh D. Cilengitide: a prototypic integrin inhibitor for the treatment of glioblastoma and other malignancies. Genes & Cancer. 2: 1159-1165. PMID 22866207 DOI: 10.1177/1947601912450586 |
0.321 |
|
| 2011 |
Weis SM, Cheresh DA. αV integrins in angiogenesis and cancer. Cold Spring Harbor Perspectives in Medicine. 1: a006478. PMID 22229119 DOI: 10.1101/Cshperspect.A006478 |
0.503 |
|
| 2011 |
Mielgo A, Seguin L, Huang M, Camargo MF, Anand S, Franovic A, Weis SM, Advani SJ, Murphy EA, Cheresh DA. A MEK-independent role for CRAF in mitosis and tumor progression. Nature Medicine. 17: 1641-5. PMID 22081024 DOI: 10.1038/Nm.2464 |
0.78 |
|
| 2011 |
Weis SM, Cheresh DA. Tumor angiogenesis: molecular pathways and therapeutic targets. Nature Medicine. 17: 1359-70. PMID 22064426 DOI: 10.1038/Nm.2537 |
0.407 |
|
| 2011 |
Aspinall RJ, Weis SM, Barnes L, Lutu-Fuga K, Bylund DJ, Pockros PJ, Cheresh DA. A Src family kinase inhibitor improves survival in experimental acute liver failure associated with elevated cerebral and circulating vascular endothelial growth factor levels. Liver International : Official Journal of the International Association For the Study of the Liver. 31: 1222-30. PMID 21745297 DOI: 10.1111/J.1478-3231.2011.02554.X |
0.365 |
|
| 2011 |
Russell RC, Sufan RI, Zhou B, Heir P, Bunda S, Sybingco SS, Greer SN, Roche O, Heathcote SA, Chow VW, Boba LM, Richmond TD, Hickey MM, Barber DL, Cheresh DA, et al. Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia. Nature Medicine. 17: 845-53. PMID 21685897 DOI: 10.1038/Nm.2370 |
0.329 |
|
| 2011 |
Schmid MC, Avraamides CJ, Dippold HC, Franco I, Foubert P, Ellies LG, Acevedo LM, Manglicmot JR, Song X, Wrasidlo W, Blair SL, Ginsberg MH, Cheresh DA, Hirsch E, Field SJ, et al. Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression. Cancer Cell. 19: 715-27. PMID 21665146 DOI: 10.1016/J.Ccr.2011.04.016 |
0.461 |
|
| 2011 |
Anand S, Cheresh DA. MicroRNA-mediated regulation of the angiogenic switch. Current Opinion in Hematology. 18: 171-6. PMID 21423013 DOI: 10.1097/Moh.0B013E328345A180 |
0.375 |
|
| 2011 |
Shields DJ, Murphy EA, Desgrosellier JS, Mielgo A, Lau SK, Barnes LA, Lesperance J, Huang M, Schmedt C, Tarin D, Lowy AM, Cheresh DA. Oncogenic Ras/Src cooperativity in pancreatic neoplasia. Oncogene. 30: 2123-34. PMID 21242978 DOI: 10.1038/Onc.2010.589 |
0.782 |
|
| 2011 |
Cheresh DA, Anand S. Abstract SY16-02: microRNA regulation of the tumor angiogenic switch Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy16-02 |
0.349 |
|
| 2011 |
Mielgo A, Murphy E, Huang M, Seguin L, Weis S, Cheresh D. Abstract 2919: Unexpected role of CRAF in tumor cell mitosis revealed by an allosteric inhibitor Cancer Research. 71: 2919-2919. DOI: 10.1158/1538-7445.Am2011-2919 |
0.486 |
|
| 2011 |
Acevedo LM, Desgrosellier J, Cheresh DA. Abstract 1474: Semaphorin 3A potentiates metastatic disease by binding to endothelial Neuropilin-1 and disrupting vascular barrier function Cancer Research. 71: 1474-1474. DOI: 10.1158/1538-7445.Am2011-1474 |
0.489 |
|
| 2010 |
Anand S, Majeti BK, Acevedo LM, Murphy EA, Mukthavaram R, Scheppke L, Huang M, Shields DJ, Lindquist JN, Lapinski PE, King PD, Weis SM, Cheresh DA. MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis. Nature Medicine. 16: 909-14. PMID 20676106 DOI: 10.1038/Nm.2186 |
0.717 |
|
| 2010 |
Garmy-Susini B, Avraamides CJ, Schmid MC, Foubert P, Ellies LG, Barnes L, Feral C, Papayannopoulou T, Lowy A, Blair SL, Cheresh D, Ginsberg M, Varner JA. Integrin alpha4beta1 signaling is required for lymphangiogenesis and tumor metastasis. Cancer Research. 70: 3042-51. PMID 20388801 DOI: 10.1158/0008-5472.Can-09-3761 |
0.473 |
|
| 2010 |
Lindquist JN, Cheresh DA, Snyder EY. Derivation of vasculature from embryonic stem cells. Current Protocols in Stem Cell Biology. Unit 1F.9. PMID 20200855 DOI: 10.1002/9780470151808.Sc01F09S12 |
0.348 |
|
| 2010 |
Murphy EA, Shields DJ, Stoletov K, Dneprovskaia E, McElroy M, Greenberg JI, Lindquist J, Acevedo LM, Anand S, Majeti BK, Tsigelny I, Saldanha A, Walsh B, Hoffman RM, Bouvet M, ... ... Cheresh DA, et al. Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF. Proceedings of the National Academy of Sciences of the United States of America. 107: 4299-304. PMID 20154271 DOI: 10.1073/Pnas.0909299107 |
0.683 |
|
| 2010 |
Shields DJ, Niessen S, Murphy EA, Mielgo A, Desgrosellier JS, Lau SK, Barnes LA, Lesperance J, Bouvet M, Tarin D, Cravatt BF, Cheresh DA. RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. Proceedings of the National Academy of Sciences of the United States of America. 107: 2189-94. PMID 20080647 DOI: 10.1073/Pnas.0911646107 |
0.768 |
|
| 2010 |
Desgrosellier JS, Cheresh DA. Integrins in cancer: biological implications and therapeutic opportunities. Nature Reviews. Cancer. 10: 9-22. PMID 20029421 DOI: 10.1038/Nrc2748 |
0.371 |
|
| 2010 |
Lau SKM, Shields DJ, Murphy EA, Cheresh DA. Abstract 5202: MUC1 oncogene is required for EGF/Src-driven carcinoma cell metastasis Cancer Research. 70: 5202-5202. DOI: 10.1158/1538-7445.Am10-5202 |
0.493 |
|
| 2010 |
Nam J, Acevedo LM, Goka E, Chen XL, Walsh C, Tanjoni I, Guan J, Weis SM, Cheresh DA, Schlaepfer DD. Abstract 389: Mice with kinase-dead FAK mutation in endothelial cells are protected from VEGF-induced permeability and are resistant to tumor cell metastasis Cancer Research. 70: 389-389. DOI: 10.1158/1538-7445.Am10-389 |
0.441 |
|
| 2010 |
Desgrosellier JS, Seguin L, Barnes LA, Shields DJ, Huang M, Lau SK, Prevost N, Tarin D, Shattil SJ, Cheresh DA. Abstract 3841: An integrin αvβ3/c-Src oncogenic unit promotes anchorage independence and tumor progression Cancer Research. 70: 3841-3841. DOI: 10.1158/1538-7445.Am10-3841 |
0.77 |
|
| 2010 |
Garmy-Susini B, Avraamides CJ, Schmid MC, Foubert P, Ellies LG, Barnes L, Feral C, Papayannopoulou T, Lowy A, Blair SL, Cheresh D, Ginsberg M, Varner JA. Integrin α4β1 signaling is required for lymphangiogenesis and tumor metastasis (Cancer Research (2010) 70, (3042-51) DOI:10.1158/0008-5472. CAN-09-3761) Cancer Research. 70: 4785. DOI: 10.1158/0008-5472.Can-10-1347 |
0.38 |
|
| 2010 |
Desgrosellier JS, Cheresh DA. Erratum: Integrins in cancer: biological implications and therapeutic opportunities Nature Reviews Cancer. 10: 890-890. DOI: 10.1038/Nrc2965 |
0.337 |
|
| 2009 |
Greenberg JI, Cheresh DA. VEGF as an inhibitor of tumor vessel maturation: implications for cancer therapy. Expert Opinion On Biological Therapy. 9: 1347-56. PMID 19761418 DOI: 10.1517/14712590903208883 |
0.443 |
|
| 2009 |
Desgrosellier JS, Barnes LA, Shields DJ, Huang M, Lau SK, Prévost N, Tarin D, Shattil SJ, Cheresh DA. An integrin alpha(v)beta(3)-c-Src oncogenic unit promotes anchorage-independence and tumor progression. Nature Medicine. 15: 1163-9. PMID 19734908 DOI: 10.1038/Nm.2009 |
0.805 |
|
| 2009 |
Koh W, Sachidanandam K, Stratman AN, Sacharidou A, Mayo AM, Murphy EA, Cheresh DA, Davis GE. Formation of endothelial lumens requires a coordinated PKCepsilon-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation. Journal of Cell Science. 122: 1812-22. PMID 19435802 DOI: 10.1242/Jcs.045799 |
0.415 |
|
| 2009 |
Weis SM, Stupack DG, Cheresh DA. Agonizing integrin antagonists? Cancer Cell. 15: 359-61. PMID 19411065 DOI: 10.1016/J.Ccr.2009.04.005 |
0.35 |
|
| 2009 |
Ricono JM, Huang M, Barnes LA, Lau SK, Weis SM, Schlaepfer DD, Hanks SK, Cheresh DA. Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasis. Cancer Research. 69: 1383-91. PMID 19208836 DOI: 10.1158/0008-5472.Can-08-3612 |
0.813 |
|
| 2009 |
Yu PT, Jaquish D, French R, Mose E, Shields D, Cheresh D, Lowy AM. 71. Plectin Binds the RON Receptor Kinase and is Required for Ligand-Dependent Migration in Pancreatic Cancer Cells Journal of Surgical Research. 151: 203. DOI: 10.1016/J.Jss.2008.11.084 |
0.383 |
|
| 2008 |
Acevedo LM, Cheresh DA. Suppressing NFAT increases VEGF signaling in hemangiomas. Cancer Cell. 14: 429-30. PMID 19061833 DOI: 10.1016/J.Ccr.2008.11.009 |
0.415 |
|
| 2008 |
Stockmann C, Doedens A, Weidemann A, Zhang N, Takeda N, Greenberg JI, Cheresh DA, Johnson RS. Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis. Nature. 456: 814-8. PMID 18997773 DOI: 10.1038/Nature07445 |
0.387 |
|
| 2008 |
Greenberg JI, Shields DJ, Barillas SG, Acevedo LM, Murphy E, Huang J, Scheppke L, Stockmann C, Johnson RS, Angle N, Cheresh DA. A role for VEGF as a negative regulator of pericyte function and vessel maturation. Nature. 456: 809-13. PMID 18997771 DOI: 10.1038/Nature07424 |
0.376 |
|
| 2008 |
Cheresh DA, Stupack DG. Regulation of angiogenesis: apoptotic cues from the ECM. Oncogene. 27: 6285-6298. PMID 18931694 DOI: 10.1038/Onc.2008.304 |
0.441 |
|
| 2008 |
Rupp PA, Visconti RP, Czirók A, Cheresh DA, Little CD. Matrix metalloproteinase 2-integrin alpha(v)beta3 binding is required for mesenchymal cell invasive activity but not epithelial locomotion: a computational time-lapse study. Molecular Biology of the Cell. 19: 5529-40. PMID 18923152 DOI: 10.1091/Mbc.E07-05-0480 |
0.399 |
|
| 2008 |
Murphy EA, Majeti BK, Barnes LA, Makale M, Weis SM, Lutu-Fuga K, Wrasidlo W, Cheresh DA. Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 9343-8. PMID 18607000 DOI: 10.1073/Pnas.0803728105 |
0.35 |
|
| 2008 |
Scheppke L, Aguilar E, Gariano RF, Jacobson R, Hood J, Doukas J, Cao J, Noronha G, Yee S, Weis S, Martin MB, Soll R, Cheresh DA, Friedlander M. Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits. The Journal of Clinical Investigation. 118: 2337-46. PMID 18483622 DOI: 10.1172/Jci33361 |
0.36 |
|
| 2008 |
Serban D, Leng J, Cheresh D. H-Ras Regulates Angiogenesis and Vascular Permeability by Activation of Distinct Downstream Effectors Circulation Research. 102: 1350-1358. PMID 18467631 DOI: 10.1161/Circresaha.107.169664 |
0.379 |
|
| 2008 |
Acevedo LM, Weis SM, Cheresh DA. Robo4 counteracts VEGF signaling. Nature Medicine. 14: 372-3. PMID 18391935 DOI: 10.1038/Nm0408-372 |
0.336 |
|
| 2008 |
Weis SM, Lim ST, Lutu-Fuga KM, Barnes LA, Chen XL, Göthert JR, Shen TL, Guan JL, Schlaepfer DD, Cheresh DA. Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK. The Journal of Cell Biology. 181: 43-50. PMID 18391070 DOI: 10.1083/Jcb.200710038 |
0.409 |
|
| 2008 |
Acevedo LM, Barillas S, Weis SM, Göthert JR, Cheresh DA. Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor. Blood. 111: 2674-80. PMID 18180379 DOI: 10.1182/Blood-2007-08-110205 |
0.377 |
|
| 2007 |
Luo JL, Tan W, Ricono JM, Korchynskyi O, Zhang M, Gonias SL, Cheresh DA, Karin M. Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin. Nature. 446: 690-4. PMID 17377533 DOI: 10.1038/Nature05656 |
0.36 |
|
| 2007 |
Alavi AS, Acevedo L, Min W, Cheresh DA. Chemoresistance of endothelial cells induced by basic fibroblast growth factor depends on Raf-1-mediated inhibition of the proapoptotic kinase, ASK1. Cancer Research. 67: 2766-72. PMID 17363598 DOI: 10.1158/0008-5472.Can-06-3648 |
0.464 |
|
| 2007 |
Weis SM, Lindquist JN, Barnes LA, Lutu-Fuga KM, Cui J, Wood MR, Cheresh DA. Cooperation between VEGF and beta3 integrin during cardiac vascular development. Blood. 109: 1962-70. PMID 17062734 DOI: 10.1182/Blood-2005-10-038893 |
0.345 |
|
| 2006 |
Doukas J, Wrasidlo W, Noronha G, Dneprovskaia E, Fine R, Weis S, Hood J, Demaria A, Soll R, Cheresh D. Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury. Proceedings of the National Academy of Sciences of the United States of America. 103: 19866-71. PMID 17172449 DOI: 10.1073/Pnas.0606956103 |
0.316 |
|
| 2006 |
Mitra SK, Mikolon D, Molina JE, Hsia DA, Hanson DA, Chi A, Lim ST, Bernard-Trifilo JA, Ilic D, Stupack DG, Cheresh DA, Schlaepfer DD. Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors. Oncogene. 25: 5969-84. PMID 16682956 DOI: 10.1038/sj.onc.1209588 |
0.409 |
|
| 2006 |
Stupack DG, Teitz T, Potter MD, Mikolon D, Houghton PJ, Kidd VJ, Lahti JM, Cheresh DA. Potentiation of neuroblastoma metastasis by loss of caspase-8. Nature. 439: 95-9. PMID 16397500 DOI: 10.1038/Nature04323 |
0.356 |
|
| 2005 |
Weis SM, Cheresh DA. Pathophysiological consequences of VEGF-induced vascular permeability. Nature. 437: 497-504. PMID 16177780 DOI: 10.1038/Nature03987 |
0.357 |
|
| 2005 |
Potter MD, Barbero S, Cheresh DA. Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and beta-catenin and maintains the cellular mesenchymal state. The Journal of Biological Chemistry. 280: 31906-12. PMID 16027153 DOI: 10.1074/Jbc.M505568200 |
0.467 |
|
| 2004 |
Stupack DG, Cheresh DA. Integrins and angiogenesis. Current Topics in Developmental Biology. 64: 207-238. PMID 15563949 DOI: 10.1016/S0070-2153(04)64009-9 |
0.452 |
|
| 2004 |
Weis S, Cui J, Barnes L, Cheresh D. Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis. The Journal of Cell Biology. 167: 223-9. PMID 15504909 DOI: 10.1083/Jcb.200408130 |
0.428 |
|
| 2004 |
Weis S, Shintani S, Weber A, Kirchmair R, Wood M, Cravens A, McSharry H, Iwakura A, Yoon YS, Himes N, Burstein D, Doukas J, Soll R, Losordo D, Cheresh D. Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction. The Journal of Clinical Investigation. 113: 885-94. PMID 15067321 DOI: 10.1172/Jci20702 |
0.354 |
|
| 2004 |
McDonald DM, Teicher BA, Stetler-Stevenson W, Ng SS, Figg WD, Folkman J, Hanahan D, Auerbach R, O'Reilly M, Herbst R, Cheresh D, Gordon M, Eggermont A, Libutti SK. Report from the society for biological therapy and vascular biology faculty of the NCI workshop on angiogenesis monitoring. Journal of Immunotherapy (Hagerstown, Md. : 1997). 27: 161-75. PMID 14770088 DOI: 10.1097/00002371-200403000-00010 |
0.36 |
|
| 2003 |
Stupack DG, Cheresh DA. Apoptotic cues from the extracellular matrix: regulators of angiogenesis. Oncogene. 22: 9022-9. PMID 14663480 DOI: 10.1038/Sj.Onc.1207110 |
0.395 |
|
| 2003 |
Hood JD, Frausto R, Kiosses WB, Schwartz MA, Cheresh DA. Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis. The Journal of Cell Biology. 162: 933-43. PMID 12952943 DOI: 10.1083/Jcb.200304105 |
0.374 |
|
| 2003 |
Hood JD, Cheresh DA. Building a better Trap. Proceedings of the National Academy of Sciences of the United States of America. 100: 8624-5. PMID 12861079 DOI: 10.1073/Pnas.1633646100 |
0.4 |
|
| 2003 |
Alavi A, Hood JD, Frausto R, Stupack DG, Cheresh DA. Role of Raf in vascular protection from distinct apoptotic stimuli. Science (New York, N.Y.). 301: 94-6. PMID 12843393 DOI: 10.1126/Science.1082015 |
0.439 |
|
| 2003 |
Hsia DA, Mitra SK, Hauck CR, Streblow DN, Nelson JA, Ilic D, Huang S, Li E, Nemerow GR, Leng J, Spencer KS, Cheresh DA, Schlaepfer DD. Differential regulation of cell motility and invasion by FAK. The Journal of Cell Biology. 160: 753-67. PMID 12615911 DOI: 10.1083/Jcb.200212114 |
0.495 |
|
| 2002 |
Hood JD, Cheresh DA. Targeted delivery of mutant Raf kinase to neovessels causes tumor regression. Cold Spring Harbor Symposia On Quantitative Biology. 67: 285-292. PMID 12858551 DOI: 10.1101/Sqb.2002.67.285 |
0.368 |
|
| 2002 |
Hood JD, Cheresh DA. Role of integrins in cell invasion and migration. Nature Reviews. Cancer. 2: 91-100. PMID 12635172 DOI: 10.1038/Nrc727 |
0.414 |
|
| 2002 |
Hauck CR, Hsia DA, Puente XS, Cheresh DA, Schlaepfer DD. FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth. The Embo Journal. 21: 6289-302. PMID 12456636 DOI: 10.1093/Emboj/Cdf631 |
0.484 |
|
| 2002 |
Stupack DG, Cheresh DA. Get a ligand, get a life: integrins, signaling and cell survival. Journal of Cell Science. 115: 3729-38. PMID 12235283 DOI: 10.1242/Jcs.00071 |
0.396 |
|
| 2002 |
Hood JD, Bednarski M, Frausto R, Guccione S, Reisfeld RA, Xiang R, Cheresh DA. Tumor regression by targeted gene delivery to the neovasculature Science. 296: 2404-2407. PMID 12089446 DOI: 10.1126/Science.1070200 |
0.389 |
|
| 2002 |
Wakasugi K, Slike BM, Hood J, Ewalt KL, Cheresh DA, Schimmel P. Induction of angiogenesis by a fragment of human tyrosyl-tRNA synthetase. The Journal of Biological Chemistry. 277: 20124-6. PMID 11956181 DOI: 10.1074/Jbc.C200126200 |
0.35 |
|
| 2002 |
Nemerow GR, Cheresh DA. Herpesvirus hijacks an integrin. Nature Cell Biology. 4: E69-71. PMID 11944033 DOI: 10.1038/Ncb0402-E69 |
0.344 |
|
| 2002 |
Kiosses WB, Hood J, Yang S, Gerritsen ME, Cheresh DA, Alderson N, Schwartz MA. A dominant-negative p65 PAK peptide inhibits angiogenesis. Circulation Research. 90: 697-702. PMID 11934838 DOI: 10.1161/01.Res.0000014227.76102.5D |
0.314 |
|
| 2002 |
Eliceiri BP, Puente XS, Hood JD, Stupack DG, Schlaepfer DD, Huang XZ, Sheppard D, Cheresh DA. Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling. The Journal of Cell Biology. 157: 149-60. PMID 11927607 DOI: 10.1083/Jcb.200109079 |
0.43 |
|
| 2002 |
Stupack DG, Cheresh DA. ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands. Science's Stke : Signal Transduction Knowledge Environment. 2002: pe7. PMID 11842241 DOI: 10.1126/Stke.2002.119.Pe7 |
0.371 |
|
| 2002 |
Wakasugi K, Slike BM, Hood J, Otani A, Ewalt KL, Friedlander M, Cheresh DA, Schimmel P. A human aminoacyl-tRNA synthetase as a regulator of angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 173-7. PMID 11773626 DOI: 10.1073/Pnas.012602099 |
0.315 |
|
| 2002 |
Otani A, Slike BM, Dorrell MI, Hood J, Kinder K, Ewalt KL, Cheresh D, Schimmel P, Friedlander M. A fragment of human TrpRS as a potent antagonist of ocular angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 178-83. PMID 11773625 DOI: 10.1073/Pnas.012601899 |
0.343 |
|
| 2002 |
Spencer KSR, Cheresh DA. VEGF-Induced Cytoskeletal Alterations Relating to Vascular Permeability in Endothelial Cells Microscopy and Microanalysis. 8: 1046-1047. DOI: 10.1017/S1431927602102911 |
0.335 |
|
| 2001 |
Stupack DG, Puente XS, Boutsaboualoy S, Storgard CM, Cheresh DA. Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins Journal of Cell Biology. 155: 459-470. PMID 11684710 DOI: 10.1083/Jcb.200106070 |
0.364 |
|
| 2001 |
Eliceiri BP, Cheresh DA. Adhesion events in angiogenesis. Current Opinion in Cell Biology. 13: 563-568. PMID 11544024 DOI: 10.1016/S0955-0674(00)00252-0 |
0.416 |
|
| 2001 |
Bello L, Francolini M, Marthyn P, Zhang J, Carroll RS, Nikas DC, Strasser JF, Villani R, Cheresh DA, Black PM. αvβ3 and αvβ5 Integrin Expression in Glioma Periphery Neurosurgery. 49: 380-390. PMID 11504114 DOI: 10.1097/00006123-200108000-00022 |
0.43 |
|
| 2001 |
Boger DL, Goldberg J, Silletti S, Kessler T, Cheresh DA. Identification of a novel class of small-molecule antiangiogenic agents through the screening of combinatorial libraries which function by inhibiting the binding and localization of proteinase MMP2 to integrin alpha(V)beta(3). Journal of the American Chemical Society. 123: 1280-8. PMID 11456699 DOI: 10.1021/Ja003579+ |
0.388 |
|
| 2001 |
Li E, Brown SL, Stupack DG, Puente XS, Cheresh DA, Nemerow GR. Integrin alpha(v)beta1 is an adenovirus coreceptor. Journal of Virology. 75: 5405-9. PMID 11333925 DOI: 10.1128/Jvi.75.11.5405-5409.2001 |
0.336 |
|
| 2001 |
Paul R, Zhang ZG, Eliceiri BP, Jiang Q, Boccia AD, Zhang RL, Chopp M, Cheresh DA. Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke. Nature Medicine. 7: 222-227. PMID 11175854 DOI: 10.1038/84675 |
0.311 |
|
| 2001 |
MacDonald TJ, Taga T, Shimada H, Tabrizi P, Zlokovic BV, Cheresh DA, Laug WE. Preferential susceptibility of brain tumors to the antiangiogenic effects of an αv integrin antagonist Neurosurgery. 48: 151-157. PMID 11152340 DOI: 10.1097/00006123-200101000-00026 |
0.357 |
|
| 2001 |
Silletti S, Kessler T, Goldberg J, Boger DL, Cheresh DA. Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo. Proceedings of the National Academy of Sciences of the United States of America. 98: 119-24. PMID 11134507 DOI: 10.1073/pnas.011343298 |
0.311 |
|
| 2001 |
Silletti S, Kessler T, Goldberg J, Boger DL, Cheresh DA. Disruption of matrix metalloproteinase 2 binding to integrin v 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo Proceedings of the National Academy of Sciences. 98: 119-124. DOI: 10.1073/Pnas.98.1.119 |
0.404 |
|
| 2000 |
Bello L, Zhang J, Nikas DC, Strasser JF, Villani RM, Cheresh DA, Carroll RS, Black PM. αvβ3 and αvβ5 Integrin expression in meningiomas Neurosurgery. 47: 1185-1195. PMID 11063113 DOI: 10.1097/00006123-200011000-00035 |
0.394 |
|
| 2000 |
Pfeifer A, Kessler T, Silletti S, Cheresh DA, Verma IM. Suppression of angiogenesis by lentiviral delivery of PEX, a noncatalytic fragment of matrix metalloproteinase 2 Proceedings of the National Academy of Sciences of the United States of America. 97: 12227-12232. PMID 11035804 DOI: 10.1073/Pnas.220399597 |
0.432 |
|
| 2000 |
Huang S, Stupack D, Liu A, Cheresh D, Nemerow GR. Cell growth and matrix invasion of EBV-immortalized human B lymphocytes is regulated by expression of α(v) integrins Oncogene. 19: 1915-1923. PMID 10773881 DOI: 10.1038/Sj.Onc.1203509 |
0.376 |
|
| 2000 |
Wang K, Guan T, Cheresh DA, Nemerow GR. Regulation of adenovirus membrane penetration by the cytoplasmic tail of integrin β5 Journal of Virology. 74: 2731-2739. PMID 10684289 DOI: 10.1128/Jvi.74.6.2731-2739.2000 |
0.31 |
|
| 1999 |
Eliceiri BP, Paul R, Schwartzberg PL, Hood JD, Leng J, Cheresh DA. Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability Molecular Cell. 4: 915-924. PMID 10635317 DOI: 10.1016/S1097-2765(00)80221-X |
0.413 |
|
| 1999 |
Collins LR, Ricketts WA, Yeh L, Cheresh D. Bifurcation of cell migratory and proliferative signaling by the adaptor protein Shc. The Journal of Cell Biology. 147: 1561-8. PMID 10613912 DOI: 10.1083/Jcb.147.7.1561 |
0.41 |
|
| 1999 |
Leng J, Klemke RL, Reddy AC, Cheresh DA. Potentiation of cell migration by adhesion-dependent cooperative signals from the GTPase Rac and Raf kinase. The Journal of Biological Chemistry. 274: 37855-61. PMID 10608850 DOI: 10.1074/Jbc.274.53.37855 |
0.702 |
|
| 1999 |
Cheresh DA, Leng J, Klemke RL. Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells. The Journal of Cell Biology. 146: 1107-16. PMID 10477763 DOI: 10.1083/Jcb.146.5.1107 |
0.669 |
|
| 1999 |
Stupack DG, Storgard CM, Cheresh DA. A role for angiogenesis in rheumatoid arthritis Brazilian Journal of Medical and Biological Research. 32: 573-581. PMID 10412569 DOI: 10.1590/S0100-879X1999000500011 |
0.33 |
|
| 1999 |
Eliceiri BP, Cheresh DA. The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development Journal of Clinical Investigation. 103: 1227-1230. PMID 10225964 DOI: 10.1172/Jci6869 |
0.475 |
|
| 1999 |
Stupack DG, Li E, Silletti SA, Kehler JA, Geahlen RL, Hahn K, Nemerow GR, Cheresh DA. Matrix valency regulates integrin-mediated lymphoid adhesion via Syk kinase Journal of Cell Biology. 144: 777-787. PMID 10037798 DOI: 10.1083/Jcb.144.4.777 |
0.443 |
|
| 1999 |
Lode HN, Moehler T, Xiang R, Jonczyk A, Gillies SD, Cheresh DA, Reisfeld RA. Synergy between an antiangiogenic integrin alphav antagonist and an antibody-cytokine fusion protein eradicates spontaneous tumor metastases. Proceedings of the National Academy of Sciences of the United States of America. 96: 1591-6. PMID 9990069 DOI: 10.1073/Pnas.96.4.1591 |
0.394 |
|
| 1999 |
Storgard CM, Stupack DG, Jonczyk A, Goodman SL, Fox RI, Cheresh DA. Decreased angiogenesis and arthritic disease in rabbits treated with an αvβ3 antagonist Journal of Clinical Investigation. 103: 47-54. PMID 9884333 DOI: 10.1172/Jci3756 |
0.32 |
|
| 1998 |
Zee RVD, Murohara T, Passeri J, Kearney M, Cheresh DA, Isner JM. Reduced Intimal Thickening Following αvβ 3 Blockade is Associated with Smooth Muscle Cell Apoptosis Cell Adhesion and Communication. 6: 371-379. PMID 10223353 DOI: 10.3109/15419069809109146 |
0.321 |
|
| 1998 |
Sipkins DA, Cheresh DA, Kazemi MR, Nevin LM, Bednarski MD, Li KC. Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging. Nature Medicine. 4: 623-6. PMID 9585240 DOI: 10.1038/Nm0598-623 |
0.41 |
|
| 1998 |
Cheresh DA. Death to a blood vessel, death to a tumor. Nature Medicine. 4: 395-396. PMID 9546782 DOI: 10.1038/Nm0498-395 |
0.39 |
|
| 1998 |
Li E, Stupack D, Klemke R, Cheresh DA, Nemerow GR. Adenovirus endocytosis via α(v) integrins requires phosphoinositide-3- OH kinase Journal of Virology. 72: 2055-2061. PMID 9499060 DOI: 10.1128/Jvi.72.3.2055-2061.1998 |
0.695 |
|
| 1998 |
Eliceiri BP, Klemke R, Strömblad S, Cheresh DA. Integrin αvβ3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis Journal of Cell Biology. 140: 1255-1263. PMID 9490736 DOI: 10.1097/00006982-199805000-00036 |
0.703 |
|
| 1998 |
Brooks PC, Silletti S, von Schalscha TL, Friedlander M, Cheresh DA. Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. Cell. 92: 391-400. PMID 9476898 DOI: 10.1097/00006982-199805000-00037 |
0.424 |
|
| 1998 |
Klemke RL, Leng J, Molander R, Brooks PC, Vuori K, Cheresh DA. CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. The Journal of Cell Biology. 140: 961-72. PMID 9472046 DOI: 10.1083/Jcb.140.4.961 |
0.661 |
|
| 1998 |
Eliceiri BP, Cheresh DA. The Role of αv Integrins during Angiogenesis Molecular Medicine. 4: 741-750. DOI: 10.1007/Bf03401768 |
0.352 |
|
| 1997 |
Felding-Habermann B, Silletti S, Mei F, Siu CH, Yip PM, Brooks PC, Cheresh DA, O'Toole TE, Ginsberg MH, Montgomery AM. A single immunoglobulin-like domain of the human neural cell adhesion molecule L1 supports adhesion by multiple vascular and platelet integrins. The Journal of Cell Biology. 139: 1567-81. PMID 9396761 DOI: 10.1083/Jcb.139.6.1567 |
0.319 |
|
| 1997 |
Boudreau N, Andrews C, Srebrow A, Ravanpay A, Cheresh DA. Induction of the angiogenic phenotype by Hox D3 Journal of Cell Biology. 139: 257-264. PMID 9314544 DOI: 10.1083/Jcb.139.1.257 |
0.353 |
|
| 1997 |
Klemke RL, Cai S, Giannini AL, Gallagher PJ, de Lanerolle P, Cheresh DA. Regulation of cell motility by mitogen-activated protein kinase. The Journal of Cell Biology. 137: 481-92. PMID 9128257 DOI: 10.1083/Jcb.137.2.481 |
0.666 |
|
| 1997 |
Brooks PC, Klemke RL, Schon S, Lewis JM, Schwartz MA, Cheresh DA. Insulin-like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo. The Journal of Clinical Investigation. 99: 1390-8. PMID 9077549 DOI: 10.1172/Jci119298 |
0.708 |
|
| 1997 |
Mousa SA, Cheresh DA. Recent advances in cell adhesion molecules and extracellular matrix proteins: potential clinical implications Drug Discovery Today. 2: 187-199. DOI: 10.1016/S1359-6446(97)01027-1 |
0.353 |
|
| 1996 |
Strömblad S, Cheresh DA. Cell adhesion and angiogenesis Trends in Cell Biology. 6: 462-468. PMID 15157503 DOI: 10.1016/0962-8924(96)84942-7 |
0.42 |
|
| 1996 |
Strömblad S, Cheresh DA. Integrins, angiogenesis and vascular cell survival. Chemistry & Biology. 3: 881-885. PMID 8939711 DOI: 10.1016/S1074-5521(96)90176-3 |
0.392 |
|
| 1996 |
Varner JA, Cheresh DA. Integrins and cancer Current Opinion in Cell Biology. 8: 724-730. PMID 8939661 DOI: 10.1016/S0955-0674(96)80115-3 |
0.462 |
|
| 1996 |
Yebra M, Parry GCN, Strömblad S, Mackman N, Rosenberg S, Mueller BM, Cheresh DA. Requirement of receptor-bound urokinase-type plasminogen activator for integrin αvβ5-directed cell migration Journal of Biological Chemistry. 271: 29393-29399. PMID 8910604 DOI: 10.1074/Jbc.271.46.29393 |
0.482 |
|
| 1996 |
Lewis JM, Cheresh DA, Schwartz MA. Protein kinase C regulates alpha v beta 5-dependent cytoskeletal associations and focal adhesion kinase phosphorylation. Journal of Cell Biology. 134: 1323-1332. PMID 8794871 DOI: 10.1083/Jcb.134.5.1323 |
0.401 |
|
| 1996 |
Strömblad S, Becker JC, Yebra M, Brooks PC, Cheresh DA. Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis. Journal of Clinical Investigation. 98: 426-433. PMID 8755653 DOI: 10.1172/Jci118808 |
0.451 |
|
| 1996 |
Brooks PC, Strömblad S, Sanders LC, von Schalscha TL, Aimes RT, Stetler-Stevenson WG, Quigley JP, Cheresh DA. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell. 85: 683-93. PMID 8646777 DOI: 10.1016/S0092-8674(00)81235-0 |
0.401 |
|
| 1996 |
Chellaiah M, Fitzgerald C, Filardo EJ, Cheresh DA, Hruska KA. Osteopontin activation of c-src in human melanoma cells requires the cytoplasmic domain of the integrin alpha v-subunit. Endocrinology. 137: 2432-40. PMID 8641196 DOI: 10.1210/Endo.137.6.8641196 |
0.378 |
|
| 1996 |
Montgomery AM, Becker JC, Siu CH, Lemmon VP, Cheresh DA, Pancook JD, Zhao X, Reisfeld RA. Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3. The Journal of Cell Biology. 132: 475-85. PMID 8636223 DOI: 10.1083/Jcb.132.3.475 |
0.367 |
|
| 1996 |
Sakamoto H, Broekelmann T, Cheresh DA, Ramirez F, Rosenbloom J, Mecham RP. Cell-type specific recognition of RGD- and non-RGD-containing cell binding domains in fibrillin-1 Journal of Biological Chemistry. 271: 4916-4922. PMID 8617764 DOI: 10.1074/Jbc.271.9.4916 |
0.371 |
|
| 1995 |
Varner JA, Brooks PC, Cheresh DA. REVIEW: the integrin alpha V beta 3: angiogenesis and apoptosis. Cell Adhesion and Communication. 3: 367-74. PMID 8821037 DOI: 10.3109/15419069509081020 |
0.319 |
|
| 1995 |
Yebra M, Filardo EJ, Bayna EM, Kawahara E, Becker JC, Cheresh DA. Induction of carcinoma cell migration on vitronectin by NF-kappa B-dependent gene expression. Molecular Biology of the Cell. 6: 841-850. PMID 7579698 DOI: 10.1091/Mbc.6.7.841 |
0.404 |
|
| 1995 |
Brooks PC, Stromblad S, Klemke R, Visscher D, Sarkar FH, Cheresh DA. Antiintegrin αvβ3 blocks human breast cancer growth and angiogenesis in human skin Journal of Clinical Investigation. 96: 1815-1822. PMID 7560073 DOI: 10.1172/Jci118227 |
0.673 |
|
| 1995 |
Filardo EJ, Brooks PC, Deming SL, Damsky C, Cheresh DA. Requirement of the NPXY motif in the integrin beta 3 subunit cytoplasmic tail for melanoma cell migration in vitro and in vivo. Journal of Cell Biology. 130: 441-450. PMID 7542248 DOI: 10.1083/Jcb.130.2.441 |
0.396 |
|
| 1995 |
Hruska KA, Rolnick F, Huskey M, Alvarez U, Cheresh D. Engagement of the osteoclast integrin alpha v beta 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity Endocrinology. 136: 2984-2992. PMID 7540546 DOI: 10.1210/Endo.136.7.7540546 |
0.401 |
|
| 1995 |
Hruska KA, Rolnick F, Huskey M, Alvarez U, Cheresh D. Engagement of the Osteoclast Integrin αvβ3 by Osteopontin Stimulates Phosphatidylinositol 3‐Hydroxyl Kinase Activityab Annals of the New York Academy of Sciences. 760: 151-165. PMID 7540372 DOI: 10.1111/J.1749-6632.1995.Tb44627.X |
0.333 |
|
| 1995 |
Liaw L, Skinner MP, Raines EW, Ross R, Cheresh DA, Schwartz SM, Giachelli CM. The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins: Role of αvβ3 in smooth muscle cell migration to osteopontin in vitro Journal of Clinical Investigation. 95: 713-724. PMID 7532190 DOI: 10.1172/Jci117718 |
0.379 |
|
| 1995 |
Friedlander M, Brooks PC, Shaffer RW, Kincaid CM, Varner JA, Cheresh DA. Definition of two angiogenic pathways by distinct alpha v integrins. Science (New York, N.Y.). 270: 1500-2. PMID 7491498 DOI: 10.1126/Science.270.5241.1500 |
0.43 |
|
| 1994 |
Brooks PC, Montgomery AM, Rosenfeld M, Reisfeld RA, Hu T, Klier G, Cheresh DA. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell. 79: 1157-64. PMID 7528107 DOI: 10.1016/0092-8674(94)90007-8 |
0.449 |
|
| 1994 |
Klemke RL, Yebra M, Bayna EM, Cheresh DA. Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin. The Journal of Cell Biology. 127: 859-66. PMID 7525598 DOI: 10.1083/Jcb.127.3.859 |
0.706 |
|
| 1994 |
Wickham TJ, Filardo EJ, Cheresh DA, Nemerow GR. Integrin αvβ5 selectively promotes adenovirus mediated cell membrane permeabilization Journal of Cell Biology. 127: 257-264. PMID 7523420 DOI: 10.1083/Jcb.127.1.257 |
0.353 |
|
| 1994 |
Montgomery AM, Reisfeld RA, Cheresh DA. Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proceedings of the National Academy of Sciences of the United States of America. 91: 8856-60. PMID 7522323 DOI: 10.1073/Pnas.91.19.8856 |
0.395 |
|
| 1994 |
Brooks PC, Clark RAF, Cheresh DA. Requirement of vascular integrin alpha v beta 3 for angiogenesis Science. 264: 569-571. PMID 7512751 DOI: 10.1126/Science.7512751 |
0.408 |
|
| 1994 |
Nemerow GR, Cheresh DA, Wickham TJ. Adenovirus entry into host cells: a role for αv integrins Trends in Cell Biology. 4: 52-55. DOI: 10.1016/0962-8924(94)90010-8 |
0.348 |
|
| 1993 |
Wickham TJ, Mathias P, Cheresh DA, Nemerow GR. Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment Cell. 73: 309-319. PMID 8477447 DOI: 10.1016/0092-8674(93)90231-E |
0.329 |
|
| 1993 |
Felding-Habermann B, Cheresh DA. Vitronectin and its receptors. Current Opinion in Cell Biology. 5: 864-868. PMID 7694604 DOI: 10.1016/0955-0674(93)90036-P |
0.432 |
|
| 1993 |
Leavesley DI, Schwartz MA, Rosenfeld M, Cheresh DA. Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms. Journal of Cell Biology. 121: 163-170. PMID 7681432 DOI: 10.1083/Jcb.121.1.163 |
0.385 |
|
| 1993 |
Gladson CL, Wilcox JN, Gillespie GY, Cheresh DA. DISTINCT GLIOBLASTOMA CELL LOCALIZATION OF INTEGRINS αvβ3 AND αvβ5 Journal of Neuropathology and Experimental Neurology. 52: 266. DOI: 10.1097/00005072-199305000-00026 |
0.359 |
|
| 1992 |
Nip J, Shibata H, Loskutoff DJ, Cheresh DA, Brodt P. Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin. Journal of Clinical Investigation. 90: 1406-1413. PMID 1383272 DOI: 10.1172/Jci116007 |
0.379 |
|
| 1992 |
Felding-Habermann B, Mueller BM, Romerdahl CA, Cheresh DA. Involvement of integrin αV gene expression in human melanoma tumorigenicity Journal of Clinical Investigation. 89: 2018-2022. PMID 1376331 DOI: 10.1172/Jci115811 |
0.412 |
|
| 1992 |
Leavesley D, Ferguson G, Wayner E, Cheresh D. Requirement of the integrin beta 3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogen Journal of Cell Biology. 117: 1101-1107. PMID 1374415 DOI: 10.1083/Jcb.117.5.1101 |
0.387 |
|
| 1992 |
Sanders LC, Felding-Habermann B, Mueller BM, Cheresh DA. Role of α(v) integrins and vitronectin in human melanoma cell growth Cold Spring Harbor Symposia On Quantitative Biology. 57: 233-240. PMID 1285050 DOI: 10.1101/Sqb.1992.057.01.028 |
0.359 |
|
| 1992 |
Cheresh DA. Structural and biologic properties of integrin-mediated cell adhesion. Clinics in Laboratory Medicine. 12: 217-236. DOI: 10.1016/S0272-2712(18)30514-6 |
0.43 |
|
| 1991 |
Gladson CL, Cheresh DA. Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells. The Journal of Clinical Investigation. 88: 1924-32. PMID 1721625 DOI: 10.1172/Jci115516 |
0.452 |
|
| 1991 |
Cheresh DA. Structure, function and biological properties of integrin α v β 3 on human melanoma cells Cancer and Metastasis Reviews. 10: 3-10. PMID 1717171 DOI: 10.1007/Bf00046839 |
0.402 |
|
| 1991 |
Wayner EA, Orlando RA, Cheresh DA. Integrins αvβ3 and αvβ5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface Journal of Cell Biology. 113: 919-929. PMID 1709170 DOI: 10.1083/Jcb.113.4.919 |
0.383 |
|
| 1991 |
Kieffer N, Fitzgerald LA, Wolf D, Cheresh DA, Phillips DR. Adhesive properties of the beta 3 integrins: comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cells. Journal of Cell Biology. 113: 451-461. PMID 1707057 DOI: 10.1083/Jcb.113.2.451 |
0.4 |
|
| 1990 |
Krissansen GW, Lucas CM, Stomski FC, Elliott MJ, Berndt MC, Boyd AW, Horton MA, Cheresh DA, Vadas MA, Burns GF. Blood leukocytes bind platelet glycoprotein (lIb–Ilia)' but do not express the vitronectin receptor International Immunology. 2: 267-277. PMID 1708278 DOI: 10.1093/Intimm/2.3.267 |
0.353 |
|
| 1990 |
Charo IF, Nannizzi L, Smith JW, Cheresh DA. The vitronectin receptor alpha v beta 3 binds fibronectin and acts in concert with alpha 5 beta 1 in promoting cellular attachment and spreading on fibronectin. Journal of Cell Biology. 111: 2795-2800. PMID 1703545 DOI: 10.1083/Jcb.111.6.2795 |
0.369 |
|
| 1990 |
Ylanne J, Cheresh D, Virtanen I. Localization of beta 1, beta 3, alpha 5, alpha v, and alpha IIb subunits of the integrin family in spreading human erythroleukemia cells. Blood. 76: 570-577. DOI: 10.1182/Blood.V76.3.570.Bloodjournal763570 |
0.383 |
|
| 1990 |
Rudolph R, Cheresh D. Cell adhesion mechanisms and their potential impact on wound healing and tumor control. Clinics in Plastic Surgery. 17: 457-462. DOI: 10.1016/S0094-1298(20)30620-9 |
0.422 |
|
| 1989 |
Hersey P, Schibeci S, Cheresh D. Augmentation of lymphocyte responses by monoclonal antibodies to the gangliosides GD3 and GD2: the role of protein kinase C, cyclic nucleotides, and intracellular calcium. Cellular Immunology. 119: 263-278. PMID 2784717 DOI: 10.1016/0008-8749(89)90243-8 |
0.354 |
|
| 1989 |
Schindler M, Meiners S, Cheresh DA. RGD-dependent linkage between plant cell wall and plasma membrane: consequences for growth. The Journal of Cell Biology. 108: 1955-65. PMID 2715184 DOI: 10.1083/Jcb.108.5.1955 |
0.369 |
|
| 1989 |
Cheresh DA, Berliner SA, Vicente V, Ruggeri ZM. Recognition of distinct adhesive sites on fibrinogen by related integrins on platelets and endothelial cells. Cell. 58: 945-953. PMID 2673537 DOI: 10.1016/0092-8674(89)90946-X |
0.34 |
|
| 1989 |
Cheresh DA, Smith JW, Cooper HM, Quaranta V. A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells Cell. 57: 59-69. PMID 2467745 DOI: 10.1016/0092-8674(89)90172-4 |
0.404 |
|
| 1988 |
Rosenberg JM, Sander DJ, Derango RE, Cheresh DA. Enzymatic basis for increased expression of GD3 on human melanoma cells derived from metastatic lesions Journal of Clinical Laboratory Analysis. 2: 91-100. DOI: 10.1002/Jcla.1860020205 |
0.348 |
|
| 1987 |
Reisfeld RA, Cheresh DA. Human tumor antigens. Advances in Immunology. 40: 323-77. PMID 3591561 DOI: 10.1016/S0065-2776(08)60242-4 |
0.331 |
|
| 1987 |
Cheresh DA, Pytela R, Pierschbacher MD, Klier FG, Ruoslahti E, Reisfeld RA. An Arg-Gly-Asp-directed receptor on the surface of human melanoma cells exists in an divalent cation-dependent functional complex with the disialoganglioside GD2. The Journal of Cell Biology. 105: 1163-73. PMID 2443507 DOI: 10.1083/Jcb.105.3.1163 |
0.356 |
|
| 1987 |
Cheresh DA. Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor Proceedings of the National Academy of Sciences of the United States of America. 84: 6471-6475. PMID 2442758 DOI: 10.1073/Pnas.84.18.6471 |
0.429 |
|
| 1986 |
Cheresh DA, Klier FG. Disialoganglioside GD2 distributes preferentially into substrate-associated microprocesses on human melanoma cells during their attachment to fibronectin. Journal of Cell Biology. 102: 1887-1897. PMID 3084502 DOI: 10.1083/Jcb.102.5.1887 |
0.339 |
|
| 1986 |
Cheresh DA, Pierschbacher MD, Herzig MA, Mujoo K. Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins. Journal of Cell Biology. 102: 688-696. PMID 3005335 DOI: 10.1083/Jcb.102.3.688 |
0.395 |
|
| 1985 |
Cheresh DA, Honsik CJ, Staffileno LK, Jung G, Reisfeld RA. Disialoganglioside GD3 on human melanoma serves as a relevant target antigen for monoclonal antibody-mediated tumor cytolysis. Proceedings of the National Academy of Sciences of the United States of America. 82: 5155-9. PMID 3860849 DOI: 10.1073/Pnas.82.15.5155 |
0.415 |
|
| 1985 |
Cheresh DA. Structural and Functional Properties of Ganglioside Antigens on Human Tumors of Neuroectodermal Origin Pathology and Immunopathology Research. 4: 97-109. PMID 2996108 DOI: 10.1159/000156968 |
0.301 |
|
| 1984 |
Cheresh DA, Harper JR, Schulz G, Reisfeld RA. Localization of the gangliosides GD2 and GD3 in adhesion plaques and on the surface of human melanoma cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 5767-71. PMID 6385004 DOI: 10.1073/Pnas.81.18.5767 |
0.361 |
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