Therese Wiedmer - Publications

Affiliations: 
University of Rochester, Rochester, NY 
Area:
Cell Biology, Immunology, Pathology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Kassas A, Moura IC, Yamashita Y, Scheffel J, Guérin-Marchand C, Blank U, Sims PJ, Wiedmer T, Monteiro RC, Rivera J, Charles N, Benhamou M. Regulation of the tyrosine phosphorylation of Phospholipid Scramblase 1 in mast cells that are stimulated through the high-affinity IgE receptor. Plos One. 9: e109800. PMID 25289695 DOI: 10.1371/Journal.Pone.0109800  0.327
2011 Chen CW, Sowden M, Zhao Q, Wiedmer T, Sims PJ. Nuclear phospholipid scramblase 1 prolongs the mitotic expansion of granulocyte precursors during G-CSF-induced granulopoiesis. Journal of Leukocyte Biology. 90: 221-33. PMID 21447647 DOI: 10.1189/Jlb.0111006  0.352
2009 Bateman A, Finn RD, Sims PJ, Wiedmer T, Biegert A, Söding J. Phospholipid scramblases and Tubby-like proteins belong to a new superfamily of membrane tethered transcription factors. Bioinformatics (Oxford, England). 25: 159-62. PMID 19010806 DOI: 10.1093/Bioinformatics/Btn595  0.464
2005 Zhou Q, Ben-Efraim I, Bigcas JL, Junqueira D, Wiedmer T, Sims PJ. Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. The Journal of Biological Chemistry. 280: 35062-8. PMID 16091359 DOI: 10.1074/Jbc.M504821200  0.483
2004 Wiedmer T, Zhao J, Li L, Zhou Q, Hevener A, Olefsky JM, Curtiss LK, Sims PJ. Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3). Proceedings of the National Academy of Sciences of the United States of America. 101: 13296-301. PMID 15328404 DOI: 10.1073/Pnas.0405354101  0.368
2004 Dong B, Zhou Q, Zhao J, Zhou A, Harty RN, Bose S, Banerjee A, Slee R, Guenther J, Williams BR, Wiedmer T, Sims PJ, Silverman RH. Phospholipid scramblase 1 potentiates the antiviral activity of interferon. Journal of Virology. 78: 8983-93. PMID 15308695 DOI: 10.1128/Jvi.78.17.8983-8993.2004  0.406
2004 Zhao KW, Li X, Zhao Q, Huang Y, Li D, Peng ZG, Shen WZ, Zhao J, Zhou Q, Chen Z, Sims PJ, Wiedmer T, Chen GQ. Protein kinase Cdelta mediates retinoic acid and phorbol myristate acetate-induced phospholipid scramblase 1 gene expression: its role in leukemic cell differentiation. Blood. 104: 3731-8. PMID 15308560 DOI: 10.1182/Blood-2004-04-1630  0.394
2004 Ben-Efraim I, Zhou Q, Wiedmer T, Gerace L, Sims PJ. Phospholipid scramblase 1 is imported into the nucleus by a receptor-mediated pathway and interacts with DNA. Biochemistry. 43: 3518-26. PMID 15035622 DOI: 10.1021/Bi0356911  0.414
2003 Nanjundan M, Sun J, Zhao J, Zhou Q, Sims PJ, Wiedmer T. Plasma membrane phospholipid scramblase 1 promotes EGF-dependent activation of c-Src through the epidermal growth factor receptor. The Journal of Biological Chemistry. 278: 37413-8. PMID 12871937 DOI: 10.1074/Jbc.M306182200  0.486
2003 Vries KJd, Wiedmer T, Sims PJ, Gadella BM. Caspase-Independent Exposure of Aminophospholipids and Tyrosine Phosphorylation in Bicarbonate Responsive Human Sperm Cells Biology of Reproduction. 68: 2122-2134. PMID 12606386 DOI: 10.1095/Biolreprod.102.012500  0.451
2003 Wiedmer T, Zhao J, Nanjundan M, Sims PJ. Palmitoylation of phospholipid scramblase 1 controls its distribution between nucleus and plasma membrane. Biochemistry. 42: 1227-33. PMID 12564925 DOI: 10.1021/Bi026679W  0.529
2002 Zhou Q, Zhao J, Wiedmer T, Sims PJ. Normal hemostasis but defective hematopoietic response to growth factors in mice deficient in phospholipid scramblase 1. Blood. 99: 4030-8. PMID 12010804 DOI: 10.1182/Blood-2001-12-0271  0.419
2002 Sun J, Nanjundan M, Pike LJ, Wiedmer T, Sims PJ. Plasma membrane phospholipid scramblase 1 is enriched in lipid rafts and interacts with the epidermal growth factor receptor. Biochemistry. 41: 6338-45. PMID 12009895 DOI: 10.1021/Bi025610L  0.421
2002 Silverman RH, Halloum A, Zhou A, Dong B, Al-Zoghaibi F, Kushner D, Zhou Q, Zhao J, Wiedmer T, Sims PJ. Suppression of ovarian carcinoma cell growth in vivo by the interferon-inducible plasma membrane protein, phospholipid scramblase 1. Cancer Research. 62: 397-402. PMID 11809687  0.35
2001 Sun J, Zhao J, Schwartz MA, Wang JY, Wiedmer T, Sims PJ. c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1. The Journal of Biological Chemistry. 276: 28984-90. PMID 11390389 DOI: 10.1074/Jbc.M102505200  0.407
2001 Sims PJ, Wiedmer T. Unraveling the mysteries of phospholipid scrambling. Thrombosis and Haemostasis. 86: 266-275. DOI: 10.1055/S-0037-1616224  0.531
2000 Wiedmer T, Zhou Q, Kwoh DY, Sims PJ. Identification of three new members of the phospholipid scramblase gene family. Biochimica Et Biophysica Acta. 1467: 244-253. PMID 10930526 DOI: 10.1016/S0005-2736(00)00236-4  0.401
2000 Tepper AD, Ruurs P, Wiedmer T, Sims PJ, Borst J, van Blitterswijk WJ. Sphingomyelin hydrolysis to ceramide during the execution phase of apoptosis results from phospholipid scrambling and alters cell-surface morphology. The Journal of Cell Biology. 150: 155-64. PMID 10893264 DOI: 10.1083/Jcb.150.1.155  0.468
2000 Zhou Q, Zhao J, Al-Zoghaibi F, Zhou A, Wiedmer T, Silverman RH, Sims PJ. Transcriptional control of the human plasma membranephospholipid scramblase 1 gene is mediated by interferon-α Blood. 95: 2593-2599. DOI: 10.1182/Blood.V95.8.2593.008K32_2593_2599  0.415
1999 Fadeel B, Gleiss B, Högstrand K, Chandra J, Wiedmer T, Sims PJ, Henter JI, Orrenius S, Samali A. Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression. Biochemical and Biophysical Research Communications. 266: 504-511. PMID 10600532 DOI: 10.1006/Bbrc.1999.1820  0.403
1998 Stout JG, Zhou Q, Wiedmer T, Sims PJ. Change in conformation of plasma membrane phospholipid scramblase induced by occupancy of its Ca2+ binding site. Biochemistry. 37: 14860-6. PMID 9778361 DOI: 10.1021/Bi9812930  0.41
1998 Zhao J, Zhou Q, Wiedmer T, Sims PJ. Palmitoylation of phospholipid scramblase is required for normal function in promoting Ca2+-activated transbilayer movement of membrane phospholipids. Biochemistry. 37: 6361-6366. PMID 9572851 DOI: 10.1021/Bi980218M  0.476
1998 Zhao J, Zhou Q, Wiedmer T, Sims PJ. Level of Expression of Phospholipid Scramblase Regulates Induced Movement of Phosphatidylserine to the Cell Surface Journal of Biological Chemistry. 273: 6603-6606. PMID 9506954 DOI: 10.1074/Jbc.273.12.6603  0.51
1998 Zhou Q, Sims PJ, Wiedmer T. Identity Of A Conserved Motif In Phospholipid Scramblase That Is Required For Ca2+-Accelerated Transbilayer Movement Of Membrane Phospholipids Biochemistry. 37: 2356-2360. PMID 9485382 DOI: 10.1021/Bi972625O  0.47
1998 Zhou Q, Sims PJ, Wiedmer T. Expression of Proteins Controlling Transbilayer Movement of Plasma Membrane Phospholipids in the B Lymphocytes From a Patient With Scott Syndrome Blood. 92: 1707-1712. DOI: 10.1182/Blood.V92.5.1707.417K15_1707_1712  0.523
1997 Zhou Q, Zhao J, Stout JG, Luhm RA, Wiedmer T, Sims PJ. Molecular cloning of human plasma membrane phospholipid scramblase. A protein mediating transbilayer movement of plasma membrane phospholipids. The Journal of Biological Chemistry. 272: 18240-4. PMID 9218461 DOI: 10.1074/Jbc.272.29.18240  0.555
1997 Zhao J, Sims PJ, Wiedmer T. Production and characterization of a mutant cell line defective in aminophospholipid translocase. Biochimica Et Biophysica Acta. 1357: 57-64. PMID 9202175 DOI: 10.1016/S0167-4889(97)00014-1  0.426
1997 Stout JG, Bassé F, Luhm RA, Weiss HJ, Wiedmer T, Sims PJ. Scott syndrome erythrocytes contain a membrane protein capable of mediating Ca2+-dependent transbilayer migration of membrane phospholipids. The Journal of Clinical Investigation. 99: 2232-8. PMID 9151796 DOI: 10.1172/Jci119397  0.499
1996 Bassé F, Stout JG, Sims PJ, Wiedmer T. Isolation of an erythrocyte membrane protein that mediates Ca2+-dependent transbilayer movement of phospholipid. The Journal of Biological Chemistry. 271: 17205-10. PMID 8663431 DOI: 10.1074/Jbc.271.29.17205  0.524
1995 Sims PJ, Wiedmer T. Induction of cellular procoagulant activity by the membrane attack complex of complement Seminars in Cell Biology. 6: 275-282. PMID 8562920 DOI: 10.1006/Scel.1995.0037  0.448
1995 Bevers EM, Wiedmer T, Comfurius P, Zhao J, Smeets EF, Schlegel RA, Schroit AJ, Weiss HJ, Williamson P, Zwaal RFA, Sims PJ. The complex of phosphatidylinositol 4,5-bisphosphate and calcium ions is not responsible for Ca2+-induced loss of phospholipid asymmetry in the human erythrocyte: a study in Scott syndrome, a disorder of calcium-induced phospholipid scrambling. Blood. 86: 1983-1991. DOI: 10.1182/Blood.V86.5.1983.Bloodjournal8651983  0.425
1994 Kojima H, Newton-Nash D, Weiss HJ, Zhao J, Sims PJ, Wiedmer T. Production and characterization of transformed B-lymphocytes expressing the membrane defect of Scott syndrome. Journal of Clinical Investigation. 94: 2237-2244. PMID 7989579 DOI: 10.1172/Jci117586  0.49
1993 Wiedmer T, Hall S, Ortel T, Kane W, Rosse W, Sims P. Complement-induced vesiculation and exposure of membrane prothrombinase sites in platelets of paroxysmal nocturnal hemoglobinuria. Blood. 82: 1192-1196. DOI: 10.1182/Blood.V82.4.1192.Bloodjournal8241192  0.486
1992 Braga LL, Ninomiya H, McCoy JJ, Eacker S, Wiedmer T, Pham C, Wood S, Sims PJ, Petri WA. Inhibition of the complement membrane attack complex by the galactose-specific adhesion of Entamoeba histolytica. The Journal of Clinical Investigation. 90: 1131-7. PMID 1381719 DOI: 10.1172/Jci115931  0.419
1992 Bevers EM, Wiedmer T, Comfurius P, Shattil SJ, Weiss HJ, Zwaal RFA, Sims PJ. Defective Ca(2+)-induced microvesiculation and deficient expression of procoagulant activity in erythrocytes from a patient with a bleeding disorder: a study of the red blood cells of Scott syndrome Blood. 79: 380-388. DOI: 10.1182/Blood.V79.2.380.Bloodjournal792380  0.459
1991 Sims PJ, Wiedmer T. The response of human platelets to activated components of the complement system. Immunology Today. 12: 338-342. PMID 1755945 DOI: 10.1016/0167-5699(91)90012-I  0.33
1991 Wiedmer T, Sims P. Participation of protein kinases in complement C5b-9-induced shedding of platelet plasma membrane vesicles. Blood. 78: 2880-2886. DOI: 10.1182/Blood.V78.11.2880.2880  0.511
1991 Gerrard J, Lint D, Sims P, Wiedmer T, Fugate R, McMillan E, Robertson C, Israels S. Identification of a platelet dense granule membrane protein that is deficient in a patient with the Hermansky-Pudlak syndrome. Blood. 77: 101-112. DOI: 10.1182/Blood.V77.1.101.Bloodjournal771101  0.466
1990 Wiedmer T, Shattil SJ, Cunningham M, Sims PJ. Role of calcium and calpain in complement-induced vesiculation of the platelet plasma membrane and in the exposure of the platelet factor Va receptor. Biochemistry. 29: 623-632. PMID 2159784 DOI: 10.1021/Bi00455A005  0.476
1989 Ando B, Wiedmer T, Sims P. The secretory release reaction initiated by complement proteins C5b-9 occurs without platelet aggregation through glycoprotein IIb-IIIa. Blood. 73: 462-467. DOI: 10.1182/Blood.V73.2.462.Bloodjournal732462  0.388
1986 Benz R, Schmid A, Wiedmer T, Sims PJ. Single-channel analysis of the conductance fluctuations induced in lipid bilayer membranes by complement proteins C5b-9. The Journal of Membrane Biology. 94: 37-45. PMID 2433454 DOI: 10.1007/Bf01901011  0.384
1986 Wiedmer T, Esmon C, Sims P. Complement proteins C5b-9 stimulate procoagulant activity through platelet prothrombinase. Blood. 68: 875-880. DOI: 10.1182/Blood.V68.4.875.875  0.389
1986 Sims P, Wiedmer T. Repolarization of the membrane potential of blood platelets after complement damage: evidence for a Ca++ -dependent exocytotic elimination of C5b-9 pores Blood. 68: 556-561. DOI: 10.1182/Blood.V68.2.556.Bloodjournal682556  0.517
1985 Wiedmer T, Sims PJ. Cyanine dye fluorescence used to measure membrane potential changes due to the assembly of complement proteins C5b-9. The Journal of Membrane Biology. 84: 249-258. PMID 4032456 DOI: 10.1007/Bf01871388  0.465
1985 Parker CJ, Wiedmer T, Sims PJ, Rosse WF. Characterization of the complement sensitivity of paroxysmal nocturnal hemoglobinuria erythrocytes. Journal of Clinical Investigation. 75: 2074-2084. PMID 4008653 DOI: 10.1172/Jci111927  0.382
1984 Sims PJ, Wiedmer T. The influence of electrochemical gradients of Na+ and K+ upon the membrane binding and pore forming activity of the terminal complement proteins. The Journal of Membrane Biology. 78: 169-176. PMID 6716452 DOI: 10.1007/Bf01869204  0.418
1984 Sims PJ, Wiedmer T. Kinetics of polymerization of a fluoresceinated derivative of complement protein C9 by the membrane-bound complex of complement proteins C5b-8. Biochemistry. 23: 3260-3267. PMID 6432040 DOI: 10.1021/Bi00309A021  0.444
1984 Pink DA, Chapman D, Laidlaw DJ, Wiedmer T. Electron spin resonance and steady-state fluorescence polarization studies of lipid bilayers containing integral proteins Biochemistry. 23: 4051-4058. PMID 6091736 DOI: 10.1021/Bi00313A007  0.36
1979 Wiedmer T, Francesco CD, Brodbeck U. Effects of Amphiphiles on Structure and Activity of Human Erythrocyte Membrane Acetylcholinesterase Febs Journal. 102: 59-64. PMID 520324 DOI: 10.1111/J.1432-1033.1979.Tb06262.X  0.419
1978 Wiedmer T, Brodbeck U, Zahler P, Fulpius BW. Interactions of acetylcholine receptor and acetylcholinesterase with lipid monolayers Biochimica Et Biophysica Acta. 506: 161-172. PMID 620025 DOI: 10.1016/0005-2736(78)90387-5  0.324
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