| Year |
Citation |
Score |
| 2021 |
Isermann T, Şener ÖÇ, Stender A, Klemke L, Winkler N, Neesse A, Li J, Wegwitz F, Moll UM, Schulz-Heddergott R. Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity. Nature Communications. 12: 4019. PMID 34188043 DOI: 10.1038/s41467-021-24064-1 |
0.419 |
|
| 2021 |
Klemke L, Fehlau CF, Winkler N, Toboll F, Singh SK, Moll UM, Schulz-Heddergott R. The Gain-of-Function p53 R248W Mutant Promotes Migration by STAT3 Deregulation in Human Pancreatic Cancer Cells. Frontiers in Oncology. 11: 642603. PMID 34178628 DOI: 10.3389/fonc.2021.642603 |
0.331 |
|
| 2020 |
Fagnan A, Bagger FO, Piqué-Borràs MR, Ignacimouttou C, Caulier A, Lopez C, Robert E, Uzan B, Gelsi-Boyer V, Aid Z, Thirant C, Moll U, Tauchmann S, Kurtovic-Kozaric A, Maciejewski JP, et al. Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers. Blood. PMID 32350520 DOI: 10.1182/Blood.2019003062 |
0.334 |
|
| 2020 |
Tutuska K, Parrilla-Monge L, Di Cesare E, Nemajerova A, Moll UM. Statin as anti-cancer therapy in autochthonous T-lymphomas expressing stabilized gain-of-function mutant p53 proteins. Cell Death & Disease. 11: 274. PMID 32332697 DOI: 10.1038/s41419-020-2466-4 |
0.411 |
|
| 2019 |
Nemajerova A, Moll UM. Tissue-specific roles of p73 in development and homeostasis. Journal of Cell Science. 132. PMID 31582429 DOI: 10.1242/jcs.233338 |
0.441 |
|
| 2019 |
Meyer G, González-Arnay E, Moll U, Nemajerova A, Tissir F, González-Gómez M. Cajal-Retzius neurons are required for the development of the human hippocampal fissure. Journal of Anatomy. PMID 30861578 DOI: 10.1111/Joa.12947 |
0.438 |
|
| 2018 |
Nemajerova A, Amelio I, Gebel J, Dötsch V, Melino G, Moll UM. Non-oncogenic roles of TAp73: from multiciliogenesis to metabolism. Cell Death and Differentiation. 25: 144-153. PMID 31745310 DOI: 10.1038/cdd.2017.178 |
0.506 |
|
| 2018 |
Schulz-Heddergott R, Stark N, Edmunds SJ, Li J, Conradi LC, Bohnenberger H, Ceteci F, Greten FR, Dobbelstein M, Moll UM. Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion. Cancer Cell. 34: 298-314.e7. PMID 30107178 DOI: 10.1016/J.Ccell.2018.07.004 |
0.321 |
|
| 2018 |
Schulz-Heddergott R, Moll UM. Gain-of-Function (GOF) Mutant p53 as Actionable Therapeutic Target. Cancers. 10. PMID 29875343 DOI: 10.3390/cancers10060188 |
0.347 |
|
| 2017 |
Nemajerova A, Amelio I, Gebel J, Dötsch V, Melino G, Moll UM. Non-oncogenic roles of TAp73: from multiciliogenesis to metabolism. Cell Death and Differentiation. PMID 29077094 DOI: 10.1038/Cdd.2017.178 |
0.511 |
|
| 2017 |
Alexandrova EM, Xu S, Moll UM. Ganetespib synergizes with cyclophosphamide to improve survival of mice with autochthonous tumors in a mutant p53-dependent manner. Cell Death & Disease. 8: e2683. PMID 28300840 DOI: 10.1038/Cddis.2017.108 |
0.302 |
|
| 2017 |
Alexandrova EM, Mirza SA, Xu S, Schulz-Heddergott R, Marchenko ND, Moll UM. p53 loss-of-heterozygosity is a necessary prerequisite for mutant p53 stabilization and gain-of-function in vivo. Cell Death & Disease. 8: e2661. PMID 28277540 DOI: 10.1038/Cddis.2017.80 |
0.494 |
|
| 2016 |
Wienken M, Moll UM, Dobbelstein M. Mdm2 as a chromatin modifier. Journal of Molecular Cell Biology. PMID 27927750 DOI: 10.1093/jmcb/mjw046 |
0.385 |
|
| 2016 |
Lebedev I, Nemajerova A, Kornaj M, Tong M, Moll UM, Seeliger MA. A novel in vitro CypD-mediated p53 aggregation assay suggests a model for mitochondrial permeability transition by chaperone systems. Journal of Molecular Biology. PMID 27515399 DOI: 10.1016/J.Jmb.2016.08.001 |
0.444 |
|
| 2016 |
Moll U. Abstract SY04-03: Improving survival by exploiting tumor dependence on stabilized mutant p53 in mouse models Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Sy04-03 |
0.549 |
|
| 2015 |
Wienken M, Dickmanns A, Nemajerova A, Kramer D, Najafova Z, Weiss M, Karpiuk O, Kassem M, Zhang Y, Lozano G, Johnsen SA, Moll UM, Zhang X, Dobbelstein M. MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53. Molecular Cell. PMID 26748827 DOI: 10.1016/J.Molcel.2015.12.008 |
0.448 |
|
| 2015 |
Yallowitz AR, Hanel W, Moll UM. Expansion of the hematopoietic stem cell compartment is necessary but not sufficient for gain-of-function mutant p53 R248Q to accelerate lymphomagenesis. Cell Death and Differentiation. 22: 1397. PMID 26045050 DOI: 10.1038/Cdd.2015.63 |
0.38 |
|
| 2015 |
Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, ... ... Moll U, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/Cdd.2014.137 |
0.343 |
|
| 2014 |
Marchenko ND, Moll UM. Mitochondrial death functions of p53. Molecular & Cellular Oncology. 1: e955995. PMID 27308326 DOI: 10.1080/23723548.2014.955995 |
0.524 |
|
| 2014 |
Senturk S, Yao Z, Camiolo M, Stiles B, Rathod T, Walsh AM, Nemajerova A, Lazzara MJ, Altorki NK, Krainer A, Moll UM, Lowe SW, Cartegni L, Sordella R. p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state. Proceedings of the National Academy of Sciences of the United States of America. 111: E3287-96. PMID 25074920 DOI: 10.1073/Pnas.1321640111 |
0.539 |
|
| 2014 |
Holembowski L, Kramer D, Riedel D, Sordella R, Nemajerova A, Dobbelstein M, Moll UM. TAp73 is essential for germ cell adhesion and maturation in testis. The Journal of Cell Biology. 204: 1173-90. PMID 24662569 DOI: 10.1083/Jcb.201306066 |
0.372 |
|
| 2014 |
Dobbelstein M, Moll U. Targeting tumour-supportive cellular machineries in anticancer drug development. Nature Reviews. Drug Discovery. 13: 179-96. PMID 24577400 DOI: 10.1038/Nrd4201 |
0.305 |
|
| 2014 |
Medina-BolÃvar C, González-Arnay E, Talos F, González-Gómez M, Moll UM, Meyer G. Cortical hypoplasia and ventriculomegaly of p73-deficient mice: Developmental and adult analysis. The Journal of Comparative Neurology. 522: 2663-79. PMID 24500610 DOI: 10.1002/Cne.23556 |
0.787 |
|
| 2014 |
Seeliger MA, Moll UM. p73 - constitutively open for business. Cell Death and Differentiation. 20: 972-3. PMID 23832148 DOI: 10.1038/Cdd.2013.56 |
0.562 |
|
| 2013 |
Zirngibl K, Moll UM. p53 further extends its reach. Oncoimmunology. 2: e24959. PMID 24255806 DOI: 10.4161/onci.24959 |
0.506 |
|
| 2013 |
Alexandrova EM, Petrenko O, Nemajerova A, Romano RA, Sinha S, Moll UM. ΔNp63 regulates select routes of reprogramming via multiple mechanisms. Cell Death and Differentiation. 20: 1698-708. PMID 24013722 DOI: 10.1038/cdd.2013.122 |
0.498 |
|
| 2013 |
Bergeaud M, Mathieu L, Guillaume A, Moll UM, Mignotte B, Le Floch N, Vayssière JL, Rincheval V. Mitochondrial p53 mediates a transcription-independent regulation of cell respiration and interacts with the mitochondrial Fâ‚F0-ATP synthase. Cell Cycle (Georgetown, Tex.). 12: 2781-93. PMID 23966169 DOI: 10.4161/cc.25870 |
0.302 |
|
| 2013 |
Hanel W, Marchenko N, Xu S, Yu SX, Weng W, Moll U. Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis. Cell Death and Differentiation. 20: 898-909. PMID 23538418 DOI: 10.1038/Cdd.2013.17 |
0.446 |
|
| 2013 |
Alexandrova EM, Moll UM. Generation of p53-deficient induced pluripotent stem cells from mouse embryo fibroblasts. Methods in Molecular Biology (Clifton, N.J.). 962: 157-64. PMID 23150445 DOI: 10.1007/978-1-62703-236-0_13 |
0.399 |
|
| 2013 |
Vaseva AV, Moll UM. Identification of p53 in mitochondria. Methods in Molecular Biology (Clifton, N.J.). 962: 75-84. PMID 23150438 DOI: 10.1007/978-1-62703-236-0_6 |
0.778 |
|
| 2013 |
Alexandrova EM, Talos F, Moll UM. p73 is dispensable for commitment to neural stem cell fate, but is essential for neural stem cell maintenance and for blocking premature differentiation. Cell Death and Differentiation. 20: 368. PMID 23099852 DOI: 10.1038/Cdd.2012.134 |
0.728 |
|
| 2012 |
Sorrentino G, Mioni M, Giorgi C, Ruggeri N, Pinton P, Moll U, Mantovani F, Del Sal G. The prolyl-isomerase Pin1 activates the mitochondrial death program of p53. Cell Death and Differentiation. 20: 198-208. PMID 22935610 DOI: 10.1038/Cdd.2012.112 |
0.585 |
|
| 2012 |
Vaseva AV, Marchenko ND, Ji K, Tsirka SE, Holzmann S, Moll UM. P53 opens the mitochondrial permeability transition pore to trigger necrosis Cell. 149: 1536-1548. PMID 22726440 DOI: 10.1016/J.Cell.2012.05.014 |
0.755 |
|
| 2012 |
Alexandrova EM, Moll UM. Role of p53 family members p73 and p63 in human hematological malignancies. Leukemia & Lymphoma. 53: 2116-29. PMID 22497596 DOI: 10.3109/10428194.2012.684348 |
0.563 |
|
| 2012 |
Hofstetter G, Berger A, Berger R, Zorić A, Braicu EI, Reimer D, Fiegl H, Marth C, Zeimet AG, Ulmer H, Moll U, Zeillinger R, Concin N. The N-terminally truncated p53 isoform Δ40p53 influences prognosis in mucinous ovarian cancer. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 22: 372-9. PMID 22246403 DOI: 10.1097/Igc.0B013E31823Ca031 |
0.504 |
|
| 2012 |
Hanel W, Moll UM. Links between mutant p53 and genomic instability. Journal of Cellular Biochemistry. 113: 433-9. PMID 22006292 DOI: 10.1002/Jcb.23400 |
0.413 |
|
| 2011 |
Zaika E, Wei J, Yin D, Andl C, Moll U, El-Rifai W, Zaika AI. p73 protein regulates DNA damage repair. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 4406-14. PMID 21891782 DOI: 10.1096/Fj.11-192815 |
0.524 |
|
| 2011 |
Li D, Marchenko ND, Moll UM. SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis. Cell Death and Differentiation. 18: 1904-13. PMID 21637290 DOI: 10.1038/cdd.2011.71 |
0.362 |
|
| 2011 |
Vaseva AV, Yallowitz AR, Marchenko ND, Xu S, Moll UM. Blockade of Hsp90 by 17AAG antagonizes MDMX and synergizes with Nutlin to induce p53-mediated apoptosis in solid tumors. Cell Death & Disease. 2: e156. PMID 21562588 DOI: 10.1038/Cddis.2011.39 |
0.793 |
|
| 2011 |
Li D, Marchenko ND, Schulz R, Fischer V, Velasco-Hernandez T, Talos F, Moll UM. Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells. Molecular Cancer Research : McR. 9: 577-88. PMID 21478269 DOI: 10.1158/1541-7786.Mcr-10-0534 |
0.806 |
|
| 2011 |
Beyer U, Moll-Rocek J, Moll UM, Dobbelstein M. Endogenous retrovirus drives hitherto unknown proapoptotic p63 isoforms in the male germ line of humans and great apes. Proceedings of the National Academy of Sciences of the United States of America. 108: 3624-9. PMID 21300884 DOI: 10.1073/pnas.1016201108 |
0.425 |
|
| 2011 |
Holembowski L, Schulz R, Talos F, Scheel A, Wolff S, Dobbelstein M, Moll U. While p73 is essential, p63 is completely dispensable for the development of the central nervous system. Cell Cycle (Georgetown, Tex.). 10: 680-9. PMID 21293190 DOI: 10.4161/Cc.10.4.14859 |
0.822 |
|
| 2010 |
Talos F, Abraham A, Vaseva AV, Holembowski L, Tsirka SE, Scheel A, Bode D, Dobbelstein M, Brück W, Moll UM. P73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis Cell Death and Differentiation. 17: 1816-1829. PMID 21076477 DOI: 10.1038/Cdd.2010.131 |
0.787 |
|
| 2010 |
Talos F, Moll UM. Role of the p53 family in stabilizing the genome and preventing polyploidization. Advances in Experimental Medicine and Biology. 676: 73-91. PMID 20687470 DOI: 10.1007/978-1-4419-6199-0_5 |
0.811 |
|
| 2010 |
Nemajerova A, Petrenko O, Trümper L, Palacios G, Moll UM. Loss of p73 promotes dissemination of Myc-induced B cell lymphomas in mice. The Journal of Clinical Investigation. 120: 2070-80. PMID 20484818 DOI: 10.1172/JCI40331 |
0.488 |
|
| 2010 |
Talos F, Schulz R, Moll UM. p63 and canonical Wnt signaling. Cell Cycle (Georgetown, Tex.). 9: 648-9. PMID 20190579 |
0.757 |
|
| 2010 |
Talos F, Wolff S, Beyer U, Dobbelstein M, Moll UM. Brdm2 - an aberrant hypomorphic p63 allele. Cell Death and Differentiation. 17: 184-186. PMID 20161489 DOI: 10.1038/Cdd.2009.158 |
0.769 |
|
| 2010 |
Hagn F, Klein C, Demmer O, Marchenko N, Vaseva A, Moll UM, Kessler H. BclxL changes conformation upon binding to wild-type but not mutant p53 DNA binding domain. The Journal of Biological Chemistry. 285: 3439-50. PMID 19955567 DOI: 10.1074/Jbc.M109.065391 |
0.745 |
|
| 2009 |
Marchenko ND, Hanel W, Li D, Becker K, Reich N, Moll UM. Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-alpha3 binding. Cell Death and Differentiation. 17: 255-67. PMID 19927155 DOI: 10.1038/cdd.2009.173 |
0.448 |
|
| 2009 |
Vaseva AV, Marchenko ND, Moll UM. The transcription-independent mitochondrial p53 program is a major contributor to nutlin-induced apoptosis in tumor cells. Cell Cycle (Georgetown, Tex.). 8: 1711-9. PMID 19411846 DOI: 10.4161/Cc.8.11.8596 |
0.808 |
|
| 2009 |
Blandino G, Moll UM. p63 regulation by microRNAs. Cell Cycle (Georgetown, Tex.). 8: 1466-7. PMID 19411828 DOI: 10.4161/cc.8.10.8784 |
0.454 |
|
| 2009 |
Wolff S, Talos F, Palacios G, Beyer U, Dobbelstein M, Moll UM. The alpha/beta carboxy-terminal domains of p63 are required for skin and limb development. New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 gamma-like proteins. Cell Death and Differentiation. 16: 1108-17. PMID 19300453 DOI: 10.1038/Cdd.2009.25 |
0.774 |
|
| 2009 |
Vaseva AV, Moll UM. The mitochondrial p53 pathway. Biochimica Et Biophysica Acta. 1787: 414-20. PMID 19007744 DOI: 10.1016/J.Bbabio.2008.10.005 |
0.804 |
|
| 2008 |
Zong WX, Moll U. p53 in autophagy control. Cell Cycle (Georgetown, Tex.). 7: 2947. PMID 18818523 DOI: 10.4161/Cc.7.19.7008 |
0.588 |
|
| 2008 |
Palacios G, Crawford HC, Vaseva A, Moll UM. Mitochondrially targeted wild-type p53 induces apoptosis in a solid human tumor xenograft model. Cell Cycle (Georgetown, Tex.). 7: 2584-90. PMID 18719383 DOI: 10.4161/Cc.7.16.6070 |
0.772 |
|
| 2008 |
Palacios G, Talos F, Nemajerova A, Moll UM, Petrenko O. E2F1 plays a direct role in Rb stabilization and p53-independent tumor suppression. Cell Cycle (Georgetown, Tex.). 7: 1776-81. PMID 18583939 DOI: 10.4161/Cc.7.12.6030 |
0.789 |
|
| 2008 |
Wolff S, Erster S, Palacios G, Moll UM. p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity. Cell Research. 18: 733-44. PMID 18504456 DOI: 10.1038/cr.2008.62 |
0.434 |
|
| 2008 |
Tasdemir E, Maiuri MC, Galluzzi L, Vitale I, Djavaheri-Mergny M, D'Amelio M, Criollo A, Morselli E, Zhu C, Harper F, Nannmark U, Samara C, Pinton P, Vicencio JM, Carnuccio R, ... Moll UM, et al. Regulation of autophagy by cytoplasmic p53. Nature Cell Biology. 10: 676-87. PMID 18454141 DOI: 10.1038/Ncb1730 |
0.536 |
|
| 2008 |
Nemajerova A, Talos F, Moll UM, Petrenko O. Rb function is required for E1A-induced S-phase checkpoint activation. Cell Death and Differentiation. 15: 1440-9. PMID 18451867 DOI: 10.1038/Cdd.2008.66 |
0.738 |
|
| 2008 |
Becker K, Marchenko ND, Palacios G, Moll UM. A role of HAUSP in tumor suppression in a human colon carcinoma xenograft model. Cell Cycle (Georgetown, Tex.). 7: 1205-13. PMID 18418047 DOI: 10.4161/cc.7.9.5756 |
0.489 |
|
| 2008 |
Marabese M, Marchini S, Marrazzo E, Mariani P, Cattaneo D, Fossati R, Compagnoni A, Signorelli M, Moll UM, Codegoni AM, Broggini M. Expression levels of p53 and p73 isoforms in stage I and stage III ovarian cancer. European Journal of Cancer (Oxford, England : 1990). 44: 131-41. PMID 18039564 DOI: 10.1016/j.ejca.2007.10.011 |
0.371 |
|
| 2007 |
Talos F, Nemajerova A, Flores ER, Petrenko O, Moll UM. p73 suppresses polyploidy and aneuploidy in the absence of functional p53. Molecular Cell. 27: 647-59. PMID 17707235 DOI: 10.1016/J.Molcel.2007.06.036 |
0.809 |
|
| 2007 |
Marchenko ND, Moll UM. The role of ubiquitination in the direct mitochondrial death program of p53. Cell Cycle (Georgetown, Tex.). 6: 1718-23. PMID 17630506 DOI: 10.4161/cc.6.14.4503 |
0.445 |
|
| 2007 |
Grollman AP, Shibutani S, Moriya M, Miller F, Wu L, Moll U, Suzuki N, Fernandes A, Rosenquist T, Medverec Z, Jakovina K, Brdar B, Slade N, Turesky RJ, Goodenough AK, et al. Aristolochic acid and the etiology of endemic (Balkan) nephropathy. Proceedings of the National Academy of Sciences of the United States of America. 104: 12129-34. PMID 17620607 DOI: 10.1073/Pnas.0701248104 |
0.355 |
|
| 2007 |
Fuster JJ, Sanz-González SM, Moll UM, Andrés V. Classic and novel roles of p53: prospects for anticancer therapy. Trends in Molecular Medicine. 13: 192-9. PMID 17383232 DOI: 10.1016/j.molmed.2007.03.002 |
0.533 |
|
| 2007 |
Becker K, Marchenko ND, Maurice M, Moll UM. Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma. Cell Death and Differentiation. 14: 1350-60. PMID 17380154 DOI: 10.1038/sj.cdd.4402126 |
0.565 |
|
| 2007 |
Nemajerova A, Mena P, Fingerle-Rowson G, Moll UM, Petrenko O. Impaired DNA damage checkpoint response in MIF-deficient mice. The Embo Journal. 26: 987-97. PMID 17290223 DOI: 10.1038/sj.emboj.7601564 |
0.49 |
|
| 2007 |
Marchenko ND, Wolff S, Erster S, Becker K, Moll UM. Monoubiquitylation promotes mitochondrial p53 translocation. The Embo Journal. 26: 923-34. PMID 17268548 DOI: 10.1038/sj.emboj.7601560 |
0.524 |
|
| 2006 |
Becker K, Pancoska P, Concin N, Vanden Heuvel K, Slade N, Fischer M, Chalas E, Moll UM. Patterns of p73 N-terminal isoform expression and p53 status have prognostic value in gynecological cancers. International Journal of Oncology. 29: 889-902. PMID 16964385 |
0.41 |
|
| 2006 |
Moll UM, Marchenko N, Zhang XK. p53 and Nur77/TR3 - transcription factors that directly target mitochondria for cell death induction. Oncogene. 25: 4725-43. PMID 16892086 DOI: 10.1038/sj.onc.1209601 |
0.469 |
|
| 2006 |
Palacios G, Moll UM. Mitochondrially targeted wild-type p53 suppresses growth of mutant p53 lymphomas in vivo. Oncogene. 25: 6133-9. PMID 16682948 DOI: 10.1038/sj.onc.1209641 |
0.562 |
|
| 2006 |
Yang X, Fraser M, Moll UM, Basak A, Tsang BK. Akt-mediated cisplatin resistance in ovarian cancer: modulation of p53 action on caspase-dependent mitochondrial death pathway. Cancer Research. 66: 3126-36. PMID 16540663 DOI: 10.1158/0008-5472.Can-05-0425 |
0.392 |
|
| 2006 |
Tomita Y, Marchenko N, Erster S, Nemajerova A, Dehner A, Klein C, Pan H, Kessler H, Pancoska P, Moll UM. WT p53, but not tumor-derived mutants, bind to Bcl2 via the DNA binding domain and induce mitochondrial permeabilization. The Journal of Biological Chemistry. 281: 8600-6. PMID 16443602 DOI: 10.1074/Jbc.M507611200 |
0.523 |
|
| 2005 |
Concin N, Hofstetter G, Berger A, Gehmacher A, Reimer D, Watrowski R, Tong D, Schuster E, Hefler L, Heim K, Mueller-Holzner E, Marth C, Moll UM, Zeimet AG, Zeillinger R. Clinical relevance of dominant-negative p73 isoforms for responsiveness to chemotherapy and survival in ovarian cancer: evidence for a crucial p53-p73 cross-talk in vivo. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 8372-83. PMID 16322298 DOI: 10.1158/1078-0432.CCR-05-0899 |
0.438 |
|
| 2005 |
Talos F, Petrenko O, Mena P, Moll UM. Mitochondrially targeted p53 has tumor suppressor activities in vivo. Cancer Research. 65: 9971-81. PMID 16267022 DOI: 10.1158/0008-5472.Can-05-1084 |
0.802 |
|
| 2005 |
Moll UM, Wolff S, Speidel D, Deppert W. Transcription-independent pro-apoptotic functions of p53. Current Opinion in Cell Biology. 17: 631-6. PMID 16226451 DOI: 10.1016/j.ceb.2005.09.007 |
0.415 |
|
| 2005 |
Nemajerova A, Wolff S, Petrenko O, Moll UM. Viral and cellular oncogenes induce rapid mitochondrial translocation of p53 in primary epithelial and endothelial cells early in apoptosis. Febs Letters. 579: 6079-83. PMID 16226255 DOI: 10.1016/j.febslet.2005.09.074 |
0.484 |
|
| 2005 |
Talos F, Mena P, Fingerle-Rowson G, Moll U, Petrenko O. MIF loss impairs Myc-induced lymphomagenesis. Cell Death & Differentiation. 12: 1319-1328. PMID 15947793 DOI: 10.1038/Sj.Cdd.4401653 |
0.769 |
|
| 2005 |
Erster S, Moll UM. Stress-induced p53 runs a transcription-independent death program. Biochemical and Biophysical Research Communications. 331: 843-50. PMID 15865940 DOI: 10.1016/j.bbrc.2005.03.187 |
0.453 |
|
| 2004 |
Erster S, Moll UM. Stress-induced p53 runs a direct mitochondrial death program: its role in physiologic and pathophysiologic stress responses in vivo. Cell Cycle (Georgetown, Tex.). 3: 1492-5. PMID 15611631 DOI: 10.4161/cc.3.12.1318 |
0.406 |
|
| 2004 |
Moll UM, Slade N. p63 and p73: roles in development and tumor formation. Molecular Cancer Research : McR. 2: 371-86. PMID 15280445 |
0.582 |
|
| 2004 |
Erster S, Mihara M, Kim RH, Petrenko O, Moll UM. In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Molecular and Cellular Biology. 24: 6728-41. PMID 15254240 DOI: 10.1128/MCB.24.15.6728-6741.2004 |
0.465 |
|
| 2004 |
Concin N, Becker K, Slade N, Erster S, Mueller-Holzner E, Ulmer H, Daxenbichler G, Zeimet A, Zeillinger R, Marth C, Moll UM. Transdominant DeltaTAp73 isoforms are frequently up-regulated in ovarian cancer. Evidence for their role as epigenetic p53 inhibitors in vivo. Cancer Research. 64: 2449-60. PMID 15059898 |
0.494 |
|
| 2003 |
Moll UM, Petrenko O. The MDM2-p53 interaction. Molecular Cancer Research : McR. 1: 1001-8. PMID 14707283 |
0.556 |
|
| 2003 |
Moll UM. The Role of p63 and p73 in tumor formation and progression: coming of age toward clinical usefulness. Commentary re: F. Koga et al., Impaired p63 expression associates with poor prognosis and uroplakin III expression in invasive urothelial carcinoma of the bladder. Clin. Cancer Res., 9: 5501-5507, 2003, and P. Puig et al., p73 Expression in human normal and tumor tissues: loss of p73alpha expression is associated with tumor progression in bladder Cancer. Clin. Cancer Res., 9: 5642-5651, 2003. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 5437-41. PMID 14654522 |
0.352 |
|
| 2003 |
Joseph TW, Zaika A, Moll UM. Nuclear and cytoplasmic degradation of endogenous p53 and HDM2 occurs during down-regulation of the p53 response after multiple types of DNA damage. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1622-30. PMID 12958168 DOI: 10.1096/fj.02-0931com |
0.541 |
|
| 2003 |
Petrenko O, Zaika A, Moll UM. deltaNp73 facilitates cell immortalization and cooperates with oncogenic Ras in cellular transformation in vivo. Molecular and Cellular Biology. 23: 5540-55. PMID 12897129 |
0.444 |
|
| 2003 |
Fingerle-Rowson G, Petrenko O, Metz CN, Forsthuber TG, Mitchell R, Huss R, Moll U, Müller W, Bucala R. The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting. Proceedings of the National Academy of Sciences of the United States of America. 100: 9354-9. PMID 12878730 DOI: 10.1073/Pnas.1533295100 |
0.537 |
|
| 2003 |
Slade N, Moll UM. Mutational analysis of p53 in human tumors: immunocytochemistry. Methods in Molecular Biology (Clifton, N.J.). 234: 231-43. PMID 12824536 DOI: 10.1385/1-59259-408-5:231 |
0.447 |
|
| 2003 |
Joseph TW, Moll UM. Analysis of nuclear and cytoplasmic degradation of p53 in cells after stress. Methods in Molecular Biology (Clifton, N.J.). 234: 211-7. PMID 12824534 DOI: 10.1385/1-59259-408-5:211 |
0.431 |
|
| 2003 |
Mihara M, Moll UM. Detection of mitochondrial localization of p53. Methods in Molecular Biology (Clifton, N.J.). 234: 203-9. PMID 12824533 DOI: 10.1385/1-59259-408-5:203 |
0.485 |
|
| 2003 |
Mihara M, Erster S, Zaika A, Petrenko O, Chittenden T, Pancoska P, Moll UM. p53 has a direct apoptogenic role at the mitochondria. Molecular Cell. 11: 577-90. PMID 12667443 DOI: 10.1016/S1097-2765(03)00050-9 |
0.542 |
|
| 2002 |
Zaika AI, Slade N, Erster SH, Sansome C, Joseph TW, Pearl M, Chalas E, Moll UM. DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors. The Journal of Experimental Medicine. 196: 765-80. PMID 12235210 |
0.528 |
|
| 2002 |
Douc-Rasy S, Barrois M, Echeynne M, Kaghad M, Blanc E, Raguenez G, Goldschneider D, Terrier-Lacombe MJ, Hartmann O, Moll U, Caput D, Bénard J. DeltaN-p73alpha accumulates in human neuroblastic tumors. The American Journal of Pathology. 160: 631-9. PMID 11839584 DOI: 10.1016/S0002-9440(10)64883-3 |
0.553 |
|
| 2002 |
Moll UM, Erster S, Zaika A. p53, p63 and p73--solos, alliances and feuds among family members. Biochimica Et Biophysica Acta. 1552: 47-59. PMID 11825686 DOI: 10.1016/S0304-419X(01)00036-1 |
0.432 |
|
| 2002 |
Shirangi TR, Zaika A, Moll UM. Nuclear degradation of p53 occurs during down-regulation of the p53 response after DNA damage. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 420-2. PMID 11790725 DOI: 10.1096/fj.01-0617fje |
0.434 |
|
| 2001 |
Moll UM, Zaika A. Nuclear and mitochondrial apoptotic pathways of p53. Febs Letters. 493: 65-9. PMID 11286997 DOI: 10.1016/S0014-5793(01)02284-0 |
0.55 |
|
| 2001 |
Sansome C, Zaika A, Marchenko ND, Moll UM. Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells. Febs Letters. 488: 110-5. PMID 11163756 DOI: 10.1016/S0014-5793(00)02368-1 |
0.544 |
|
| 2001 |
Sansome C, Zaika A, Marchenko ND, Moll UM. Corrigendum to: Hypoxia death stimulus induces translocation of p53 protein to mitochondria Febs Letters. 501: 97-98. DOI: 10.1016/S0014-5793(01)02531-5 |
0.36 |
|
| 2000 |
Moll UM, Zaika A. Disrupting the p53-mdm2 interaction as a potential therapeutic modality. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 3: 217-221. PMID 11498389 DOI: 10.1054/drup.2000.0160 |
0.557 |
|
| 2000 |
Zaika A, Irwin M, Sansome C, Moll UM. Oncogenes induce and activate endogenous p73 protein. The Journal of Biological Chemistry. 276: 11310-6. PMID 11115495 DOI: 10.1074/JBC.M005737200 |
0.568 |
|
| 2000 |
Marchenko ND, Zaika A, Moll UM. Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. The Journal of Biological Chemistry. 275: 16202-12. PMID 10821866 DOI: 10.1074/JBC.275.21.16202 |
0.523 |
|
| 1999 |
Zaika A, Marchenko N, Moll UM. Cytoplasmically "sequestered" wild type p53 protein is resistant to Mdm2-mediated degradation. The Journal of Biological Chemistry. 274: 27474-80. PMID 10488081 DOI: 10.1074/JBC.274.39.27474 |
0.526 |
|
| 1999 |
Stommel JM, Marchenko ND, Jimenez GS, Moll UM, Hope TJ, Wahl GM. A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. The Embo Journal. 18: 1660-72. PMID 10075936 DOI: 10.1093/Emboj/18.6.1660 |
0.516 |
|
| 1998 |
Kovalev S, Marchenko ND, Gugliotta BG, Chalas E, Chumas J, Moll UM. Loss of p53 function in uterine papillary serous carcinoma. Human Pathology. 29: 613-9. PMID 9635683 DOI: 10.1016/S0046-8177(98)80012-9 |
0.511 |
|
| 1998 |
Moll UM, Schramm LM. p53--an acrobat in tumorigenesis. Critical Reviews in Oral Biology and Medicine : An Official Publication of the American Association of Oral Biologists. 9: 23-37. PMID 9488246 DOI: 10.1177/10454411980090010101 |
0.538 |
|
| 1997 |
Marchenko ND, Moll UM. Nuclear overexpression of p53 protein does not correlate with gene mutation in primary peritoneal carcinoma. Human Pathology. 28: 1002-6. PMID 9308722 DOI: 10.1016/S0046-8177(97)90051-4 |
0.427 |
|
| 1997 |
Moll UM, Valea F, Chumas J. Role of p53 alteration in primary peritoneal carcinoma. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. 16: 156-62. PMID 9100070 DOI: 10.1097/00004347-199704000-00012 |
0.356 |
|
| 1997 |
Ostermeyer AG, Runko E, Winkfield B, Ahn B, Moll UM. Cytoplasmically sequestered wild-type p53 protein in neuroblastoma is relocated to the nucleus by a C-terminal peptide. Proceedings of the National Academy of Sciences of the United States of America. 93: 15190-4. PMID 8986786 DOI: 10.1073/pnas.93.26.15190 |
0.501 |
|
| 1996 |
Lang C, Herrmann M, ElMaghrabi M, Abumrad N, Lane M, Baunoch D, Moll U. No mutations within conserved domain I of the p53 gene in medullary thyroid cancer. Oncology Reports. 3: 269-271. PMID 21594357 DOI: 10.3892/Or.3.2.269 |
0.397 |
|
| 1996 |
Moll UM, Chalas E, Auguste M, Meaney D, Chumas J. Uterine papillary serous carcinoma evolves via a p53-driven pathway. Human Pathology. 27: 1295-300. PMID 8958301 DOI: 10.1016/S0046-8177(96)90340-8 |
0.451 |
|
| 1996 |
Moll UM, Ostermeyer AG, Haladay R, Winkfield B, Frazier M, Zambetti G. Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage. Molecular and Cellular Biology. 16: 1126-37. PMID 8622657 DOI: 10.1128/MCB.16.3.1126 |
0.524 |
|
| 1996 |
Moll UM, Ostermeyer AG, Ahomadegbe JC, Mathieu MC, Riou G. p53 mediated tumor cell response to chemotherapeutic DNA damage: a preliminary study in matched pairs of breast cancer biopsies. Human Pathology. 26: 1293-301. PMID 8522300 DOI: 10.1016/0046-8177(95)90292-9 |
0.477 |
|
| 1995 |
Moll UM, LaQuaglia M, Bénard J, Riou G. Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proceedings of the National Academy of Sciences of the United States of America. 92: 4407-11. PMID 7753819 DOI: 10.1073/Pnas.92.10.4407 |
0.49 |
|
| 1993 |
Riou G, Lê MG, Travagli JP, Levine AJ, Moll UM. Poor prognosis of p53 gene mutation and nuclear overexpression of p53 protein in inflammatory breast carcinoma. Journal of the National Cancer Institute. 85: 1765-7. PMID 8411261 DOI: 10.1093/jnci/85.21.1765 |
0.336 |
|
| 1992 |
Moll UM, Riou G, Levine AJ. Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proceedings of the National Academy of Sciences of the United States of America. 89: 7262-6. PMID 1353891 DOI: 10.1073/pnas.89.15.7262 |
0.409 |
|
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