| Year |
Citation |
Score |
| 2023 |
Shakya A, Liu P, Godek J, McKee NW, Dodson M, Anandhan A, Ooi A, Garcia JGN, Costa M, Chapman E, Zhang DD. The NRF2-p97-NRF2 negative feedback loop. Redox Biology. 65: 102839. PMID 37573837 DOI: 10.1016/j.redox.2023.102839 |
0.328 |
|
| 2023 |
Modi R, McKee N, Zhang N, Alwali A, Nelson S, Lohar A, Ostafe R, Zhang DD, Parkinson EI. Stapled Peptides as Direct Inhibitors of Nrf2-sMAF Transcription Factors. Journal of Medicinal Chemistry. PMID 37097833 DOI: 10.1021/acs.jmedchem.2c02037 |
0.357 |
|
| 2023 |
Shakya A, McKee NW, Dodson M, Chapman E, Zhang DD. Anti-Ferroptotic Effects of Nrf2: Beyond the Antioxidant Response. Molecules and Cells. 46: 165-175. PMID 36994475 DOI: 10.14348/molcells.2023.0005 |
0.399 |
|
| 2022 |
Dodson M, Chen J, Shakya A, Anandhan A, Zhang DD. The dark side of NRF2 in arsenic carcinogenesis. Advances in Pharmacology (San Diego, Calif.). 96: 47-69. PMID 36858779 DOI: 10.1016/bs.apha.2022.08.002 |
0.332 |
|
| 2022 |
Dodson M, Dai W, Anandhan A, Schmidlin CJ, Liu P, Wilson NC, Wei Y, Kitamura N, Galligan JJ, Ooi A, Chapman E, Zhang DD. CHML is an NRF2 target gene that regulates mTOR function. Molecular Oncology. PMID 35184380 DOI: 10.1002/1878-0261.13194 |
0.335 |
|
| 2021 |
Sivinski J, Zhang DD, Chapman E. Targeting NRF2 to Treat Cancer. Seminars in Cancer Biology. PMID 34102289 DOI: 10.1016/j.semcancer.2021.06.003 |
0.445 |
|
| 2021 |
Schmidlin CJ, Shakya A, Dodson M, Chapman E, Zhang DD. The Intricacies of NRF2 Regulation in Cancer. Seminars in Cancer Biology. PMID 34020028 DOI: 10.1016/j.semcancer.2021.05.016 |
0.415 |
|
| 2020 |
Liu P, Luo G, Dodson M, Schmidlin CJ, Wei Y, Kerimoglu B, Ooi A, Chapman E, Garcia JG, Zhang DD. The NRF2-LOC344887 signaling axis suppresses pulmonary fibrosis. Redox Biology. 38: 101766. PMID 33126057 DOI: 10.1016/j.redox.2020.101766 |
0.31 |
|
| 2020 |
Ferrari M, Zevini A, Palermo E, Muscolini M, Alexandridi M, Etna MP, Coccia EM, Fernandez-Sesma A, Coyne C, Zhang D, Marques ETA, Olagnier D, Hiscott J. Dengue virus targets Nrf2 for NS2B3-mediated degradation leading to enhanced oxidative stress and viral replication. Journal of Virology. PMID 32999020 DOI: 10.1128/JVI.01551-20 |
0.301 |
|
| 2020 |
Schmidlin CJ, Rojo de la Vega M, Perer J, Zhang DD, Wondrak GT. Activation of NRF2 by topical apocarotenoid treatment mitigates radiation-induced dermatitis. Redox Biology. 37: 101714. PMID 32927319 DOI: 10.1016/J.Redox.2020.101714 |
0.419 |
|
| 2020 |
Schmidlin CJ, Zeng T, Liu P, Wei Y, Dodson M, Chapman E, Zhang DD. Chronic arsenic exposure enhances metastatic potential via NRF2-mediated upregulation of SOX9. Toxicology and Applied Pharmacology. 115138. PMID 32682831 DOI: 10.1016/J.Taap.2020.115138 |
0.454 |
|
| 2020 |
Zhang DD, Chapman E. The role of natural products in revealing NRF2 function. Natural Product Reports. PMID 32400766 DOI: 10.1039/C9Np00061E |
0.444 |
|
| 2020 |
Anandhan A, Dodson M, Schmidlin CJ, Liu P, Zhang DD. Breakdown of an Ironclad Defense System: The Critical Role of NRF2 in Mediating Ferroptosis. Cell Chemical Biology. 27: 436-447. PMID 32275864 DOI: 10.1016/J.Chembiol.2020.03.011 |
0.448 |
|
| 2020 |
Liu P, Dodson M, Fang D, Chapman E, Zhang DD. NRF2 negatively regulates primary ciliogenesis and hedgehog signaling. Plos Biology. 18: e3000620. PMID 32053600 DOI: 10.1371/Journal.Pbio.3000620 |
0.474 |
|
| 2019 |
Rodrigues SD, Santos SS, Meireles T, Romero N, Glorieux G, Pecoits-Filho R, Zhang DD, Nakao LS. Uremic toxins promote accumulation of oxidized protein and increased sensitivity to hydrogen peroxide in endothelial cells by impairing the autophagic flux. Biochemical and Biophysical Research Communications. PMID 31837804 DOI: 10.1016/J.Bbrc.2019.12.022 |
0.401 |
|
| 2019 |
Liu P, Kerins MJ, Tian W, Neupane D, Zhang DD, Ooi A. Differential and overlapping targets of the transcriptional regulators NRF1, NRF2, and NRF3 in human cells. The Journal of Biological Chemistry. PMID 31628195 DOI: 10.1074/Jbc.Ra119.009591 |
0.446 |
|
| 2019 |
Liu P, Tian W, Tao S, Tillotson J, Wijeratne EMK, Gunatilaka AAL, Zhang DD, Chapman E. Non-covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation. Cell Chemical Biology. PMID 31402317 DOI: 10.1016/J.Chembiol.2019.07.011 |
0.485 |
|
| 2019 |
Schmidlin CJ, Dodson MB, Zhang DD. Filtering through the role of NRF2 in kidney disease. Archives of Pharmacal Research. PMID 31372933 DOI: 10.1007/S12272-019-01177-2 |
0.395 |
|
| 2019 |
Ambrose AJ, Zerio CJ, Sivinski J, Schmidlin CJ, Shi T, Ross AB, Widrick KJ, Johnson SM, Zhang DD, Chapman E. A high throughput substrate binding assay reveals hexachlorophene as an inhibitor of the ER-resident HSP70 chaperone GRP78. Bioorganic & Medicinal Chemistry Letters. PMID 31129054 DOI: 10.1016/J.Bmcl.2019.05.041 |
0.388 |
|
| 2019 |
Kerins MJ, Liu P, Tian W, Mannheim W, Zhang D, Ooi A. Genome wide CRISPR screen reveals autophagy disruption as the convergence mechanism that regulates the NRF2 transcription factor. Molecular and Cellular Biology. PMID 31010806 DOI: 10.1128/Mcb.00037-19 |
0.459 |
|
| 2019 |
Liu P, de la Vega MR, Dodson M, Yue F, Shi B, Fang D, Chapman E, Liu L, Zhang DD. Spermidine confers liver protection by enhancing NRF2 signaling through a MAP1S-mediated non-canonical mechanism. Hepatology (Baltimore, Md.). PMID 30873635 DOI: 10.1002/Hep.30616 |
0.413 |
|
| 2019 |
Xiao Y, Riahi R, Torab P, Zhang DD, Wong PK. Collective Cell Migration in 3D Epithelial Wound Healing. Acs Nano. PMID 30758172 DOI: 10.1021/Acsnano.8B06305 |
0.33 |
|
| 2019 |
Dodson M, Castro-Portuguez R, Zhang DD. NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis. Redox Biology. 101107. PMID 30692038 DOI: 10.1016/J.Redox.2019.101107 |
0.456 |
|
| 2019 |
Schmidlin CJ, Dodson MB, Madhavan L, Zhang DD. Redox Regulation by NRF2 in Aging and Disease. Free Radical Biology & Medicine. PMID 30654017 DOI: 10.1016/J.Freeradbiomed.2019.01.016 |
0.381 |
|
| 2018 |
Liu P, Rojo de la Vega M, Sammani S, Mascarenhas JB, Kerins M, Dodson M, Sun X, Wang T, Ooi A, Garcia JGN, Zhang DD. RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE-dependent repression. Proceedings of the National Academy of Sciences of the United States of America. PMID 30309964 DOI: 10.1073/Pnas.1812125115 |
0.459 |
|
| 2018 |
Dodson M, de la Vega MR, Cholanians AB, Schmidlin CJ, Chapman E, Zhang DD. Modulating NRF2 in Disease: Timing Is Everything. Annual Review of Pharmacology and Toxicology. PMID 30256716 DOI: 10.1146/Annurev-Pharmtox-010818-021856 |
0.445 |
|
| 2018 |
Wei J, Yuan Y, Chen L, Xu Y, Zhang Y, Wang Y, Yang Y, Peek CB, Diebold L, Yang Y, Gao B, Jin C, Melo-Cardenas J, Chandel NS, Zhang DD, et al. ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes. Nature Communications. 9: 3659. PMID 30201971 DOI: 10.1038/S41467-018-06091-7 |
0.328 |
|
| 2018 |
Yang Y, Kong S, Zhang Y, Melo-Cardenas J, Gao B, Zhang Y, Zhang DD, Zhang B, Song J, Thorp E, Zhang K, Zhang J, Fang D. The endoplasmic reticulum--resident E3 ubiquitin ligase Hrd1 controls a critical checkpoint in B- cell development in mice. The Journal of Biological Chemistry. PMID 29907570 DOI: 10.1074/Jbc.Ra117.001267 |
0.332 |
|
| 2018 |
Ray S, Corenblum MJ, Anandhan A, Reed A, Ortiz FO, Zhang DD, Barnes CA, Madhavan L. A Role for Nrf2 Expression in Defining the Aging of Hippocampal Neural Stem Cells. Cell Transplantation. 963689718774030. PMID 29871525 DOI: 10.1177/0963689718774030 |
0.341 |
|
| 2018 |
Rojo de la Vega M, Chapman E, Zhang DD. NRF2 and the Hallmarks of Cancer. Cancer Cell. PMID 29731393 DOI: 10.1016/J.Ccell.2018.03.022 |
0.469 |
|
| 2018 |
Rojo de la Vega M, Zhang DD, Wondrak GT. Topical Bixin Confers NRF2-Dependent Protection Against Photodamage and Hair Graying in Mouse Skin. Frontiers in Pharmacology. 9: 287. PMID 29636694 DOI: 10.3389/Fphar.2018.00287 |
0.42 |
|
| 2018 |
Dodson M, Liu P, Jiang T, Ambrose AJ, Luo G, Rojo de la Vega M, Cholanians AB, Wong PK, Chapman E, Zhang DD. Increased O-GlcNAcylation of SNAP29 drives arsenic-induced autophagic dysfunction. Molecular and Cellular Biology. PMID 29507186 DOI: 10.1128/Mcb.00595-17 |
0.376 |
|
| 2018 |
Dodson M, de la Vega MR, Harder B, Castro-Portuguez R, Rodrigues SD, Wong PK, Chapman E, Zhang DD. Low-level arsenic causes proteotoxic stress and not oxidative stress. Toxicology and Applied Pharmacology. 341: 106-113. PMID 29408041 DOI: 10.1016/J.Taap.2018.01.014 |
0.38 |
|
| 2018 |
Wang S, Xiao Y, Zhang DD, Wong PK. A gapmer aptamer nanobiosensor for real-time monitoring of transcription and translation in single cells. Biomaterials. 156: 56-64. PMID 29190498 DOI: 10.1016/J.Biomaterials.2017.11.026 |
0.354 |
|
| 2017 |
Rojo de la Vega M, Krajisnik A, Zhang DD, Wondrak GT. Targeting NRF2 for Improved Skin Barrier Function and Photoprotection: Focus on the Achiote-Derived Apocarotenoid Bixin. Nutrients. 9. PMID 29258247 DOI: 10.3390/Nu9121371 |
0.432 |
|
| 2017 |
Tian W, Rojo de la Vega M, Schmidlin CJ, Ooi A, Zhang DD. Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2). The Journal of Biological Chemistry. PMID 29255090 DOI: 10.1074/Jbc.Ra117.000428 |
0.464 |
|
| 2017 |
Dodson M, Zhang DD. Non-canonical activation of NRF2: New insights and its relevance to disease. Current Pathobiology Reports. 5: 171-176. PMID 29082113 DOI: 10.1007/S40139-017-0131-0 |
0.411 |
|
| 2017 |
Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, ... ... Zhang DD, et al. Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Cell. 171: 273-285. PMID 28985560 DOI: 10.1016/J.Cell.2017.09.021 |
0.369 |
|
| 2017 |
Tao S, de la Vega MR, Chapman E, Ooi A, Zhang DD. The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer. Molecular Carcinogenesis. PMID 28976703 DOI: 10.1002/Mc.22745 |
0.441 |
|
| 2017 |
Long M, Li X, Li L, Dodson M, Zhang DD, Zheng H. Multifunctional p62 Effects Underlie Diverse Metabolic Diseases. Trends in Endocrinology and Metabolism: Tem. PMID 28966079 DOI: 10.1016/J.Tem.2017.09.001 |
0.342 |
|
| 2017 |
Tillotson J, Kedzior M, Guimarães L, Ross AB, Peters TL, Ambrose AJ, Schmidlin CJ, Zhang DD, Costa-Lotufo LV, Rodríguez AD, Schatz JH, Chapman E. ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A. Bioorganic & Medicinal Chemistry Letters. PMID 28757063 DOI: 10.1016/J.Bmcl.2017.07.045 |
0.386 |
|
| 2017 |
Tillotson J, Zerio CJ, Harder B, Ambrose A, Jung KS, Kang M, Zhang DD, Chapman E. Arsenic compromises both p97 and proteasome functions. Chemical Research in Toxicology. PMID 28636814 DOI: 10.1021/Acs.Chemrestox.7B00158 |
0.363 |
|
| 2017 |
Gao B, Kong Q, Zhang Y, Yun C, Dent SYR, Song J, Zhang DD, Wang Y, Li X, Fang D. The Histone Acetyltransferase Gcn5 Positively Regulates T Cell Activation. Journal of Immunology (Baltimore, Md. : 1950). PMID 28424240 DOI: 10.4049/Jimmunol.1600312 |
0.349 |
|
| 2017 |
Tao S, Liu P, Luo G, Rojo de la Vega M, Chen H, Wu T, Tillotson J, Chapman E, Zhang DD. p97 Negatively Regulates NRF2 by Extracting Ubiquitylated NRF2 from the KEAP1-CUL3 E3 Complex. Molecular and Cellular Biology. PMID 28115426 DOI: 10.1128/Mcb.00660-16 |
0.461 |
|
| 2017 |
Bao L, Wu J, Dodson M, Rojo de la Vega EM, Ning Y, Zhang Z, Yao M, Zhang DD, Xu C, Yi X. ABCF2, an Nrf2 target gene, contributes to cisplatin resistance in ovarian cancer cells. Molecular Carcinogenesis. PMID 28112439 DOI: 10.1002/Mc.22615 |
0.436 |
|
| 2017 |
de la Vega MR, Wondrak G, Zhang D. The Apocarotenoid Bixin Protects Mouse Skin against UV-induced Damage in an NRF2-dependent Manner Free Radical Biology and Medicine. 112: 194. DOI: 10.1016/J.Freeradbiomed.2017.10.306 |
0.392 |
|
| 2017 |
Dodson M, Zhang DD. Arsenic-induced Metabolic Reprogramming: A Role for Autophagy, NRF2, and OGlcNAcylation Free Radical Biology and Medicine. 112: 186. DOI: 10.1016/J.Freeradbiomed.2017.10.290 |
0.454 |
|
| 2016 |
de la Vega MR, Dodson M, Chapman E, Zhang DD. NRF2-targeted therapeutics: New targets and modes of NRF2 regulation. Current Opinion in Toxicology. 1: 62-70. PMID 29082352 DOI: 10.1016/J.Cotox.2016.10.005 |
0.479 |
|
| 2016 |
Harder B, Tian W, La Clair JJ, Tan AC, Ooi A, Chapman E, Zhang DD. Brusatol overcomes chemoresistance through inhibition of protein translation. Molecular Carcinogenesis. PMID 28019675 DOI: 10.1002/Mc.22609 |
0.522 |
|
| 2016 |
Kong S, Yang Y, Xu Y, Wang Y, Zhang Y, Melo-Cardenas J, Xu X, Gao B, Thorp EB, Zhang DD, Zhang B, Song J, Zhang K, Zhang J, Zhang J, et al. Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas. Proceedings of the National Academy of Sciences of the United States of America. PMID 27573825 DOI: 10.1073/Pnas.1606742113 |
0.369 |
|
| 2016 |
Wang S, Sun J, Zhang DD, Wong PK. A nanobiosensor for dynamic single cell analysis during microvascular self-organization. Nanoscale. PMID 27547924 DOI: 10.1039/C6Nr03907C |
0.313 |
|
| 2016 |
Wang H, Rojo de la Vega M, Zhang DD, Yu S, Zheng H. Response to comment on "NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis". Science Translational Medicine. 8: 349lr1. PMID 27464746 DOI: 10.1126/Scitranslmed.Aag1805 |
0.34 |
|
| 2016 |
Xu Y, Zhao F, Qiu Q, Chen K, Wei J, Kong Q, Gao B, Melo-Cardenas J, Zhang B, Zhang J, Song J, Zhang DD, Zhang J, Fan Y, Li H, et al. The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity. Nature Communications. 7: 12073. PMID 27417417 DOI: 10.1038/Ncomms12073 |
0.334 |
|
| 2016 |
de la Vega MR, Dodson M, Gross C, Manzour H, Lantz RC, Chapman E, Wang T, Black SM, Garcia JG, Zhang DD. Role of Nrf2 and Autophagy in Acute Lung Injury. Current Pharmacology Reports. 2: 91-101. PMID 27313980 DOI: 10.1007/S40495-016-0053-2 |
0.404 |
|
| 2016 |
Sun J, Hoying JB, Deymier PA, Zhang DD, Wong PK. Cellular Architecture Regulates Collective Calcium Signaling and Cell Contractility. Plos Computational Biology. 12: e1004955. PMID 27196735 DOI: 10.1371/Journal.Pcbi.1004955 |
0.303 |
|
| 2016 |
Corenblum MJ, Ray S, Remley QW, Long M, Harder B, Zhang DD, Barnes CA, Madhavan L. Reduced Nrf2 expression mediates the decline in neural stem cell function during a critical middle-age period. Aging Cell. PMID 27095375 DOI: 10.1111/Acel.12482 |
0.33 |
|
| 2016 |
Wang H, Liu X, Long M, Huang Y, Zhang L, Zhang R, Zheng Y, Liao X, Wang Y, Liao Q, Li W, Tang Z, Tong Q, Wang X, Fang F, ... ... Zhang DD, et al. NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis. Science Translational Medicine. 8: 334ra51. PMID 27075625 DOI: 10.1126/Scitranslmed.Aad6095 |
0.407 |
|
| 2016 |
Melo-Cardenas J, Zhang Y, Zhang DD, Fang D. Ubiquitin-specific peptidase 22 functions and its involvement in disease. Oncotarget. PMID 27057639 DOI: 10.18632/Oncotarget.8602 |
0.409 |
|
| 2016 |
Chen W, Li S, Li J, Zhou W, Wu S, Xu S, Cui K, Zhang DD, Liu B. Artemisitene activates the Nrf2-dependent antioxidant response and protects against bleomycin-induced lung injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27006451 DOI: 10.1096/Fj.201500109R |
0.494 |
|
| 2016 |
Wang Y, Wang Y, Zhang Z, Park JY, Guo D, Liao H, Yi X, Zheng Y, Zhang D, Chambers SK, Zheng W. Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-AKR1C1 pathway. Oncotarget. PMID 26824415 DOI: 10.18632/Oncotarget.7004 |
0.4 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... Zhang DD, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.364 |
|
| 2016 |
Tao S, Rojo de la Vega M, Quijada H, Wondrak GT, Wang T, Garcia JG, Zhang DD. Bixin protects mice against ventilation-induced lung injury in an NRF2-dependent manner. Scientific Reports. 6: 18760. PMID 26729554 DOI: 10.1038/Srep18760 |
0.353 |
|
| 2016 |
Johnson J, Puga A, Wallace KB, Zhang DD. Editorial overview: Nrf2 in Toxicology: An update Current Opinion in Toxicology. 1: iv-vi. DOI: 10.1016/S2468-2020(16)30057-2 |
0.338 |
|
| 2016 |
Rojo de la Vega M, Tao S, Park S, Zhang D, Wondrak G. The achiote-derived apocarotenoid bixin protects skin against environmental insults through NRF2-dependent activation of the epidermal antioxidant response Toxicology Letters. 259: S196-S197. DOI: 10.1016/J.Toxlet.2016.07.468 |
0.356 |
|
| 2016 |
Dodson M, Zhang D. Chronic Arsenic-Induced Metabolic Syndrome: A Role for Prolonged Nrf2 Activation and Mitochondrial Metabolism Free Radical Biology and Medicine. 100: S183. DOI: 10.1016/J.Freeradbiomed.2016.10.482 |
0.403 |
|
| 2015 |
Long M, Rojo de la Vega M, Wen Q, Bharara M, Jiang T, Zhang R, Zhou S, Wong PK, Wondrak GT, Zheng H, Zhang DD. An essential role of NRF2 in diabetic wound healing. Diabetes. PMID 26718502 DOI: 10.2337/Db15-0564 |
0.336 |
|
| 2015 |
Yin YW, Jin HJ, Zhao W, Gao B, Fang J, Wei J, Zhang DD, Zhang J, Fang D. The Histone Acetyltransferase GCN5 Expression Is Elevated and Regulated by c-Myc and E2F1 Transcription Factors in Human Colon Cancer. Gene Expression. 16: 187-96. PMID 26637399 DOI: 10.3727/105221615X14399878166230 |
0.447 |
|
| 2015 |
Qian Z, Zhou T, Gurguis CI, Xu X, Wen Q, Lv J, Fang F, Hecker L, Cress AE, Natarajan V, Jacobson JR, Zhang DD, Garcia JG, Wang T. Nuclear factor, erythroid 2-like 2-associated molecular signature predicts lung cancer survival. Scientific Reports. 5: 16889. PMID 26596768 DOI: 10.1038/Srep16889 |
0.387 |
|
| 2015 |
Harder B, Jiang T, Wu T, Tao S, de la Vega MR, Tian W, Chapman E, Zhang DD. Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention. Biochemical Society Transactions. 43: 680-6. PMID 26551712 DOI: 10.1042/Bst20150020 |
0.532 |
|
| 2015 |
Tao S, Park SL, de la Vega MR, Zhang DD, Wondrak GT. Systemic administration of the apocarotenoid bixin protects skin against solar UV-induced damage through activation of NRF2. Free Radical Biology & Medicine. PMID 26456052 DOI: 10.1016/J.Freeradbiomed.2015.08.028 |
0.407 |
|
| 2015 |
Jiang T, Harder B, Vega MR, Wong PK, Chapman E, Zhang DD. p62 links autophagy and Nrf2 signaling. Free Radical Biology & Medicine. PMID 26117325 DOI: 10.1016/J.Freeradbiomed.2015.06.014 |
0.551 |
|
| 2015 |
Tao S, Tillotson J, Wijeratne EM, Xu YM, Kang M, Wu T, Lau EC, Mesa C, Mason DJ, Brown RV, La Clair JJ, Gunatilaka AA, Zhang DD, Chapman E. Withaferin A Analogs That Target the AAA+ Chaperone p97. Acs Chemical Biology. PMID 26006219 DOI: 10.1021/Acschembio.5B00367 |
0.376 |
|
| 2015 |
Shen T, Jiang T, Long M, Chen J, Ren D, Wong PK, Chapman E, Zhou B, Zhang DD. A curcumin derivative that inhibits vinyl carbamate-induced lung carcinogenesis via activation of the Nrf2 protective response. Antioxidants & Redox Signaling. PMID 25891177 DOI: 10.1089/Ars.2014.6074 |
0.38 |
|
| 2015 |
Riahi R, Sun J, Wang S, Long M, Zhang DD, Wong PK. Notch1-Dll4 signalling and mechanical force regulate leader cell formation during collective cell migration. Nature Communications. 6: 6556. PMID 25766473 DOI: 10.1038/Ncomms7556 |
0.399 |
|
| 2015 |
Long M, Tao S, Rojo de la Vega M, Jiang T, Wen Q, Park SL, Zhang DD, Wondrak GT. Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde. Cancer Prevention Research (Philadelphia, Pa.). 8: 444-54. PMID 25712056 DOI: 10.1158/1940-6207.Capr-14-0359 |
0.421 |
|
| 2015 |
Canet MJ, Merrell MD, Harder BG, Maher JM, Wu T, Lickteig AJ, Jackson JP, Zhang DD, Yamamoto M, Cherrington NJ. Identification of a functional antioxidant response element within the eighth intron of the human ABCC3 gene. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 93-9. PMID 25349122 DOI: 10.1124/Dmd.114.060103 |
0.409 |
|
| 2015 |
Bao L, Jaramillo MC, Zhang Z, Zheng Y, Yao M, Zhang DD, Yi X. Induction of autophagy contributes to cisplatin resistance in human ovarian cancer cells. Molecular Medicine Reports. 11: 91-8. PMID 25322694 DOI: 10.3892/Mmr.2014.2671 |
0.42 |
|
| 2014 |
Nam KH, Jamilpour N, Mfoumou E, Wang FY, Zhang DD, Wong PK. Probing mechanoregulation of neuronal differentiation by plasma lithography patterned elastomeric substrates. Scientific Reports. 4: 6965. PMID 25376886 DOI: 10.1038/Srep06965 |
0.324 |
|
| 2014 |
Tao S, Wang S, Moghaddam SJ, Ooi A, Chapman E, Wong PK, Zhang DD. Oncogenic KRAS confers chemoresistance by upregulating NRF2. Cancer Research. 74: 7430-41. PMID 25339352 DOI: 10.1158/0008-5472.Can-14-1439 |
0.435 |
|
| 2014 |
Wu T, Harder BG, Wong PK, Lang JE, Zhang DD. Oxidative stress, mammospheres and Nrf2-new implication for breast cancer therapy? Molecular Carcinogenesis. PMID 25154499 DOI: 10.1002/Mc.22202 |
0.526 |
|
| 2014 |
Kang MJ, Wu T, Wijeratne EM, Lau EC, Mason DJ, Mesa C, Tillotson J, Zhang DD, Gunatilaka AA, La Clair JJ, Chapman E. Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action. Chembiochem : a European Journal of Chemical Biology. 15: 2125-31. PMID 25125376 DOI: 10.1002/Cbic.201402258 |
0.332 |
|
| 2014 |
Riahi R, Wang S, Long M, Li N, Chiou PY, Zhang DD, Wong PK. Mapping photothermally induced gene expression in living cells and tissues by nanorod-locked nucleic acid complexes. Acs Nano. 8: 3597-605. PMID 24645754 DOI: 10.1021/Nn500107G |
0.334 |
|
| 2014 |
Wu T, Zhao F, Gao B, Tan C, Yagishita N, Nakajima T, Wong PK, Chapman E, Fang D, Zhang DD. Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis. Genes & Development. 28: 708-22. PMID 24636985 DOI: 10.1101/Gad.238246.114 |
0.405 |
|
| 2014 |
Shen T, Chen XM, Harder B, Long M, Wang XN, Lou HX, Wondrak GT, Ren DM, Zhang DD. Plant extracts of the family Lauraceae: a potential resource for chemopreventive agents that activate the nuclear factor-erythroid 2-related factor 2/antioxidant response element pathway. Planta Medica. 80: 426-34. PMID 24585092 DOI: 10.1055/S-0034-1368197 |
0.489 |
|
| 2014 |
Riahi R, Long M, Yang Y, Dean Z, Zhang DD, Slepian MJ, Wong PK. Single cell gene expression analysis in injury-induced collective cell migration. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 192-202. PMID 24336811 DOI: 10.1039/C3Ib40095F |
0.356 |
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| 2014 |
Wu T, Wang XJ, Tian W, Jaramillo MC, Lau A, Zhang DD. Poly(ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription. Free Radical Biology & Medicine. 67: 69-80. PMID 24140708 DOI: 10.1016/J.Freeradbiomed.2013.10.806 |
0.787 |
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| 2014 |
Jiang T, Tian F, Zheng H, Whitman SA, Lin Y, Zhang Z, Zhang N, Zhang DD. Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-κB-mediated inflammatory response. Kidney International. 85: 333-43. PMID 24025640 DOI: 10.1038/Ki.2013.343 |
0.423 |
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| 2014 |
Wu T, Elisa BH, De La Vega Guinea R, Tao S, Tian W, Jiang T, Ooi A, Chapman E, Zhang DD. Nrf2 REGULATION AND ITS DUAL ROLE IN CANCER Free Radical Biology and Medicine. 76: S6. DOI: 10.1016/J.Freeradbiomed.2014.10.018 |
0.399 |
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| 2013 |
Tao S, Justiniano R, Zhang DD, Wondrak GT. The Nrf2-inducers tanshinone I and dihydrotanshinone protect human skin cells and reconstructed human skin against solar simulated UV. Redox Biology. 1: 532-41. PMID 24273736 DOI: 10.1016/J.Redox.2013.10.004 |
0.381 |
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| 2013 |
Jaramillo MC, Zhang DD. The emerging role of the Nrf2-Keap1 signaling pathway in cancer. Genes & Development. 27: 2179-91. PMID 24142871 DOI: 10.1101/Gad.225680.113 |
0.518 |
|
| 2013 |
Qiao S, Tao S, Rojo de la Vega M, Park SL, Vonderfecht AA, Jacobs SL, Zhang DD, Wondrak GT. The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death. Autophagy. 9: 2087-102. PMID 24113242 DOI: 10.4161/Auto.26506 |
0.436 |
|
| 2013 |
Chen W, Wang H, Tao S, Zheng Y, Wu W, Lian F, Jaramillo M, Fang D, Zhang DD. Tumor protein translationally controlled 1 is a p53 target gene that promotes cell survival. Cell Cycle (Georgetown, Tex.). 12: 2321-8. PMID 24067374 DOI: 10.4161/Cc.25404 |
0.424 |
|
| 2013 |
Qiu Q, Zheng Z, Chang L, Zhao YS, Tan C, Dandekar A, Zhang Z, Lin Z, Gui M, Li X, Zhang T, Kong Q, Li H, Chen S, Chen A, ... ... Zhang D, et al. Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis. The Embo Journal. 32: 2477-90. PMID 23942232 DOI: 10.1038/Emboj.2013.183 |
0.325 |
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| 2013 |
Whitman SA, Long M, Wondrak GT, Zheng H, Zhang DD. Nrf2 modulates contractile and metabolic properties of skeletal muscle in streptozotocin-induced diabetic atrophy. Experimental Cell Research. 319: 2673-83. PMID 23896025 DOI: 10.1016/J.Yexcr.2013.07.015 |
0.3 |
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| 2013 |
Riahi R, Dean Z, Wu TH, Teitell MA, Chiou PY, Zhang DD, Wong PK. Detection of mRNA in living cells by double-stranded locked nucleic acid probes. The Analyst. 138: 4777-85. PMID 23772441 DOI: 10.1039/C3An00722G |
0.312 |
|
| 2013 |
Villeneuve NF, Tian W, Wu T, Sun Z, Lau A, Chapman E, Fang D, Zhang DD. USP15 negatively regulates Nrf2 through deubiquitination of Keap1. Molecular Cell. 51: 68-79. PMID 23727018 DOI: 10.1016/J.Molcel.2013.04.022 |
0.815 |
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| 2013 |
Ji L, Li H, Gao P, Shang G, Zhang DD, Zhang N, Jiang T. Nrf2 pathway regulates multidrug-resistance-associated protein 1 in small cell lung cancer. Plos One. 8: e63404. PMID 23667609 DOI: 10.1371/Journal.Pone.0063404 |
0.477 |
|
| 2013 |
Lau A, Zheng Y, Tao S, Wang H, Whitman SA, White E, Zhang DD. Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner. Molecular and Cellular Biology. 33: 2436-46. PMID 23589329 DOI: 10.1128/Mcb.01748-12 |
0.79 |
|
| 2013 |
Tao S, Zheng Y, Lau A, Jaramillo MC, Chau BT, Lantz RC, Wong PK, Wondrak GT, Zhang DD. Tanshinone I activates the Nrf2-dependent antioxidant response and protects against As(III)-induced lung inflammation in vitro and in vivo. Antioxidants & Redox Signaling. 19: 1647-61. PMID 23394605 DOI: 10.1089/Ars.2012.5117 |
0.774 |
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| 2013 |
Lau A, Whitman SA, Jaramillo MC, Zhang DD. Arsenic-mediated activation of the Nrf2-Keap1 antioxidant pathway. Journal of Biochemical and Molecular Toxicology. 27: 99-105. PMID 23188707 DOI: 10.1002/Jbt.21463 |
0.79 |
|
| 2013 |
Lau A, Tian W, Whitman SA, Zhang DD. The predicted molecular weight of Nrf2: it is what it is not. Antioxidants & Redox Signaling. 18: 91-3. PMID 22703241 DOI: 10.1089/Ars.2012.4754 |
0.767 |
|
| 2012 |
Zheng Y, Tao S, Lian F, Chau BT, Chen J, Sun G, Fang D, Lantz RC, Zhang DD. Sulforaphane prevents pulmonary damage in response to inhaled arsenic by activating the Nrf2-defense response. Toxicology and Applied Pharmacology. 265: 292-9. PMID 22975029 DOI: 10.1016/J.Taap.2012.08.028 |
0.408 |
|
| 2012 |
Wang F, Tian F, Whitman SA, Zhang DD, Nishinaka T, Zhang N, Jiang T. Regulation of transforming growth factor β1-dependent aldose reductase expression by the Nrf2 signal pathway in human mesangial cells. European Journal of Cell Biology. 91: 774-81. PMID 22951256 DOI: 10.1016/J.Ejcb.2012.07.004 |
0.452 |
|
| 2012 |
Bray K, Mathew R, Lau A, Kamphorst JJ, Fan J, Chen J, Chen HY, Ghavami A, Stein M, DiPaola RS, Zhang D, Rabinowitz JD, White E. Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition. Plos One. 7: e41831. PMID 22848625 DOI: 10.1371/Journal.Pone.0041831 |
0.75 |
|
| 2012 |
Chen W, Jiang T, Wang H, Tao S, Lau A, Fang D, Zhang DD. Does Nrf2 contribute to p53-mediated control of cell survival and death? Antioxidants & Redox Signaling. 17: 1670-5. PMID 22559194 DOI: 10.1089/Ars.2012.4674 |
0.77 |
|
| 2012 |
Lin Z, Yang H, Kong Q, Li J, Lee SM, Gao B, Dong H, Wei J, Song J, Zhang DD, Fang D. USP22 antagonizes p53 transcriptional activation by deubiquitinating Sirt1 to suppress cell apoptosis and is required for mouse embryonic development. Molecular Cell. 46: 484-94. PMID 22542455 DOI: 10.1016/J.Molcel.2012.03.024 |
0.471 |
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| 2012 |
Hu Q, Zhang DD, Wang L, Lou H, Ren D. Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 50: 1927-32. PMID 22465804 DOI: 10.1016/J.Fct.2012.03.059 |
0.458 |
|
| 2012 |
Riahi R, Yang Y, Zhang DD, Wong PK. Advances in wound-healing assays for probing collective cell migration. Journal of Laboratory Automation. 17: 59-65. PMID 22357609 DOI: 10.1177/2211068211426550 |
0.316 |
|
| 2012 |
Ma J, Cai H, Wu T, Sobhian B, Huo Y, Alcivar A, Mehta M, Cheung KL, Ganesan S, Kong AN, Zhang DD, Xia B. PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function. Molecular and Cellular Biology. 32: 1506-17. PMID 22331464 DOI: 10.1128/Mcb.06271-11 |
0.429 |
|
| 2012 |
Bray K, Mathew R, Lau A, Kamphorst JJ, Fan J, Chen J, Chen H, Ghavami A, Stein M, DiPaola RS, Zhang D, Rabinowitz JD, White E. Cell death induced by autophagy and mTOR inhibition is RIPK-dependent necroptosis. Plos One. DOI: 10.1371/Journal.Pone.0041831.G003 |
0.74 |
|
| 2011 |
Zheng H, Whitman SA, Wu W, Wondrak GT, Wong PK, Fang D, Zhang DD. Therapeutic potential of Nrf2 activators in streptozotocin-induced diabetic nephropathy. Diabetes. 60: 3055-66. PMID 22025779 DOI: 10.2337/Db11-0807 |
0.306 |
|
| 2011 |
Kong S, Kim SJ, Sandal B, Lee SM, Gao B, Zhang DD, Fang D. The type III histone deacetylase Sirt1 protein suppresses p300-mediated histone H3 lysine 56 acetylation at Bclaf1 promoter to inhibit T cell activation. The Journal of Biological Chemistry. 286: 16967-75. PMID 21454709 DOI: 10.1074/Jbc.M111.218206 |
0.383 |
|
| 2011 |
Sun Z, Wu T, Zhao F, Lau A, Birch CM, Zhang DD. KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response. Molecular and Cellular Biology. 31: 1800-11. PMID 21383067 DOI: 10.1128/Mcb.05036-11 |
0.785 |
|
| 2011 |
Ren D, Villeneuve NF, Jiang T, Wu T, Lau A, Toppin HA, Zhang DD. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Proceedings of the National Academy of Sciences of the United States of America. 108: 1433-8. PMID 21205897 DOI: 10.1073/Pnas.1014275108 |
0.801 |
|
| 2010 |
Wondrak GT, Villeneuve NF, Lamore SD, Bause AS, Jiang T, Zhang DD. The cinnamon-derived dietary factor cinnamic aldehyde activates the Nrf2-dependent antioxidant response in human epithelial colon cells. Molecules (Basel, Switzerland). 15: 3338-55. PMID 20657484 DOI: 10.3390/Molecules15053338 |
0.716 |
|
| 2010 |
Hur W, Sun Z, Jiang T, Mason DE, Peters EC, Zhang DD, Luesch H, Schultz PG, Gray NS. A small-molecule inducer of the antioxidant response element. Chemistry & Biology. 17: 537-47. PMID 20534351 DOI: 10.1016/J.Chembiol.2010.03.013 |
0.499 |
|
| 2010 |
Jiang T, Chen N, Zhao F, Wang XJ, Kong B, Zheng W, Zhang DD. High levels of Nrf2 determine chemoresistance in type II endometrial cancer. Cancer Research. 70: 5486-96. PMID 20530669 DOI: 10.1158/0008-5472.Can-10-0713 |
0.472 |
|
| 2010 |
Villeneuve NF, Lau A, Zhang DD. Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases. Antioxidants & Redox Signaling. 13: 1699-712. PMID 20486766 DOI: 10.1089/Ars.2010.3211 |
0.813 |
|
| 2010 |
Zhang DD. The Nrf2-Keap1-ARE signaling pathway: The regulation and dual function of Nrf2 in cancer. Antioxidants & Redox Signaling. 13: 1623-6. PMID 20486759 DOI: 10.1089/Ars.2010.3301 |
0.5 |
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| 2010 |
Lau A, Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD. A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62. Molecular and Cellular Biology. 30: 3275-85. PMID 20421418 DOI: 10.1128/Mcb.00248-10 |
0.81 |
|
| 2010 |
Jiang T, Huang Z, Lin Y, Zhang Z, Fang D, Zhang DD. The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy. Diabetes. 59: 850-60. PMID 20103708 DOI: 10.2337/Db09-1342 |
0.323 |
|
| 2009 |
Villeneuve NF, Sun Z, Chen W, Zhang DD. Nrf2 and p21 regulate the fine balance between life and death by controlling ROS levels. Cell Cycle (Georgetown, Tex.). 8: 3255-6. PMID 19806015 DOI: 10.4161/Cc.8.20.9565 |
0.76 |
|
| 2009 |
Sun Z, Huang Z, Zhang DD. Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response. Plos One. 4: e6588. PMID 19668370 DOI: 10.1371/Journal.Pone.0006588 |
0.481 |
|
| 2009 |
Chen A, Gao B, Zhang J, McEwen T, Ye SQ, Zhang D, Fang D. The HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T-cell death by catalyzing EGR2 ubiquitination. Molecular and Cellular Biology. 29: 5348-56. PMID 19651900 DOI: 10.1128/Mcb.00407-09 |
0.431 |
|
| 2009 |
Zhao F, Wu T, Lau A, Jiang T, Huang Z, Wang XJ, Chen W, Wong PK, Zhang DD. Nrf2 promotes neuronal cell differentiation. Free Radical Biology & Medicine. 47: 867-79. PMID 19573594 DOI: 10.1016/J.Freeradbiomed.2009.06.029 |
0.739 |
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| 2009 |
Chen W, Sun Z, Wang XJ, Jiang T, Huang Z, Fang D, Zhang DD. Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response. Molecular Cell. 34: 663-73. PMID 19560419 DOI: 10.1016/J.Molcel.2009.04.029 |
0.459 |
|
| 2009 |
Jiang T, Huang Z, Chan JY, Zhang DD. Nrf2 protects against As(III)-induced damage in mouse liver and bladder. Toxicology and Applied Pharmacology. 240: 8-14. PMID 19538980 DOI: 10.1016/J.Taap.2009.06.010 |
0.462 |
|
| 2009 |
Wang XJ, Zhang DD. Ectodermal-neural cortex 1 down-regulates Nrf2 at the translational level. Plos One. 4: e5492. PMID 19424503 DOI: 10.1371/Journal.Pone.0005492 |
0.506 |
|
| 2009 |
Sun Z, Chin YE, Zhang DD. Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response. Molecular and Cellular Biology. 29: 2658-72. PMID 19273602 DOI: 10.1128/Mcb.01639-08 |
0.46 |
|
| 2008 |
Lau A, Villeneuve NF, Sun Z, Wong PK, Zhang DD. Dual roles of Nrf2 in cancer Pharmacological Research. 58: 262-270. PMID 18838122 DOI: 10.1016/J.Phrs.2008.09.003 |
0.816 |
|
| 2008 |
Du Y, Villeneuve NF, Wang XJ, Sun Z, Chen W, Li J, Lou H, Wong PK, Zhang DD. Oridonin confers protection against arsenic-induced toxicity through activation of the Nrf2-mediated defensive response. Environmental Health Perspectives. 116: 1154-61. PMID 18795156 DOI: 10.1289/Ehp.11464 |
0.747 |
|
| 2008 |
Wondrak GT, Cabello CM, Villeneuve NF, Zhang S, Ley S, Li Y, Sun Z, Zhang DD. Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress. Free Radical Biology & Medicine. 45: 385-95. PMID 18482591 DOI: 10.1016/J.Freeradbiomed.2008.04.023 |
0.727 |
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| 2008 |
Wang XJ, Sun Z, Chen W, Li Y, Villeneuve NF, Zhang DD. Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction. Toxicology and Applied Pharmacology. 230: 383-9. PMID 18417180 DOI: 10.1016/J.Taap.2008.03.003 |
0.745 |
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| 2008 |
Wang XJ, Sun Z, Villeneuve NF, Zhang S, Zhao F, Li Y, Chen W, Yi X, Zheng W, Wondrak GT, Wong PK, Zhang DD. Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2. Carcinogenesis. 29: 1235-43. PMID 18413364 DOI: 10.1093/Carcin/Bgn095 |
0.747 |
|
| 2008 |
Gao B, Lee SM, Chen A, Zhang J, Zhang DD, Kannan K, Ortmann RA, Fang D. Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis. Embo Reports. 9: 480-5. PMID 18369366 DOI: 10.1038/Embor.2008.37 |
0.452 |
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| 2008 |
WANG Z, GIDWANI V, SUN Z, ZHANG D, WONG P. Development of a Molecular Assay for Rapid Screening of Chemopreventive Compounds Targeting Nrf2 Journal of the Association For Laboratory Automation. 13: 243-248. DOI: 10.1016/J.Jala.2008.03.007 |
0.349 |
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| 2007 |
Wang XJ, Sun Z, Chen W, Eblin KE, Gandolfi JA, Zhang DD. Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity. Toxicology and Applied Pharmacology. 225: 206-13. PMID 17765279 DOI: 10.1016/J.Taap.2007.07.016 |
0.5 |
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| 2007 |
Sun Z, Zhang S, Chan JY, Zhang DD. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2. Molecular and Cellular Biology. 27: 6334-49. PMID 17636022 DOI: 10.1128/Mcb.00630-07 |
0.504 |
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| 2006 |
Zhang DD. Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metabolism Reviews. 38: 769-89. PMID 17145701 DOI: 10.1080/03602530600971974 |
0.529 |
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| 2005 |
Ansell PJ, Lo SC, Newton LG, Espinosa-Nicholas C, Zhang DD, Liu JH, Hannink M, Lubahn DB. Repression of cancer protective genes by 17beta-estradiol: ligand-dependent interaction between human Nrf2 and estrogen receptor alpha. Molecular and Cellular Endocrinology. 243: 27-34. PMID 16198475 DOI: 10.1016/J.Mce.2005.08.002 |
0.44 |
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| 2005 |
Zhang DD, Lo SC, Sun Z, Habib GM, Lieberman MW, Hannink M. Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway. The Journal of Biological Chemistry. 280: 30091-9. PMID 15983046 DOI: 10.1074/Jbc.M501279200 |
0.457 |
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| 2004 |
Li X, Zhang D, Hannink M, Beamer LJ. Crystallization and initial crystallographic analysis of the Kelch domain from human Keap1. Acta Crystallographica. Section D, Biological Crystallography. 60: 2346-8. PMID 15583386 DOI: 10.1107/S0907444904024825 |
0.352 |
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| 2004 |
Zhang DD, Lo SC, Cross JV, Templeton DJ, Hannink M. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Molecular and Cellular Biology. 24: 10941-53. PMID 15572695 DOI: 10.1128/Mcb.24.24.10941-10953.2004 |
0.486 |
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| 2003 |
Zhang DD, Hannink M. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Molecular and Cellular Biology. 23: 8137-51. PMID 14585973 DOI: 10.1128/Mcb.23.22.8137-8151.2003 |
0.503 |
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| 2003 |
Cullinan SB, Zhang D, Hannink M, Arvisais E, Kaufman RJ, Diehl JA. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Molecular and Cellular Biology. 23: 7198-209. PMID 14517290 DOI: 10.1128/Mcb.23.20.7198-7209.2003 |
0.494 |
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| 2000 |
Sachdev S, Bagchi S, Zhang DD, Mings AC, Hannink M. Nuclear import of IkappaBalpha is accomplished by a ran-independent transport pathway. Molecular and Cellular Biology. 20: 1571-82. PMID 10669735 DOI: 10.1128/Mcb.20.5.1571-1582.2000 |
0.354 |
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