Gino Cortopassi - Publications

Affiliations: 
University of California, Davis, Davis, CA 
Area:
Molecular Biology, Ophthalmology

86 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Amorim R, Magalhães CC, Benfeito S, Cagide F, Tavares LC, Santos K, Sardão VA, Datta S, Cortopassi GA, Baldeiras I, Jones JG, Borges F, Oliveira PJ, Teixeira J. Mitochondria dysfunction induced by decyl-TPP mitochondriotropic antioxidant based on caffeic acid AntiOxCIN sensitizes cisplatin lung anticancer therapy due to a remodeling of energy metabolism. Biochemical Pharmacology. 115953. PMID 38036191 DOI: 10.1016/j.bcp.2023.115953  0.386
2023 Jin LW, Di Lucente J, Ruiz Mendiola U, Suthprasertporn N, Tomilov A, Cortopassi G, Kim K, Ramsey JJ, Maezawa I. The ketone body β-hydroxybutyrate shifts microglial metabolism and suppresses amyloid-β oligomer-induced inflammation in human microglia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 37: e23261. PMID 37878335 DOI: 10.1096/fj.202301254R  0.33
2022 Abeti R, Jasoliya M, Al-Mahdawi S, Pook M, Gonzalez-Robles C, Hui CK, Cortopassi G, Giunti P. A Drug Combination Rescues Frataxin-Dependent Neural and Cardiac Pathophysiology in FA Models. Frontiers in Molecular Biosciences. 9: 830650. PMID 35664670 DOI: 10.3389/fmolb.2022.830650  0.307
2021 De Mario A, Tosatto A, Hill JM, Kriston-Vizi J, Ketteler R, Vecellio Reane D, Cortopassi G, Szabadkai G, Rizzuto R, Mammucari C. Identification and functional validation of FDA-approved positive and negative modulators of the mitochondrial calcium uniporter. Cell Reports. 35: 109275. PMID 34161774 DOI: 10.1016/j.celrep.2021.109275  0.323
2021 Zhou Z, Hagopian K, López-Domínguez JA, Kim K, Jasoliya M, Roberts MN, Cortopassi GA, Showalter MR, Roberts BS, González-Reyes JA, Baar K, Rutkowsky J, Ramsey JJ. A ketogenic diet impacts markers of mitochondrial mass in a tissue specific manner in aged mice. Aging. 13. PMID 33735837 DOI: 10.18632/aging.202834  0.351
2021 Hui CK, Dedkova EN, Montgomery C, Cortopassi G. Dimethyl fumarate dose-dependently increases mitochondrial gene expression and function in muscle and brain of Friedreich's ataxia model mice. Human Molecular Genetics. PMID 33432356 DOI: 10.1093/hmg/ddaa282  0.353
2021 Datta S, Sears T, Cortopassi G, Woolard K, Angelastro JM. Repurposing FDA approved drugs inhibiting mitochondrial function for targeting glioma-stem like cells. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 133: 111058. PMID 33378970 DOI: 10.1016/j.biopha.2020.111058  0.38
2019 Crakes KR, Santos Rocha C, Grishina I, Hirao LA, Napoli E, Gaulke CA, Fenton A, Datta S, Arredondo J, Marco ML, Sankaran-Walters S, Cortopassi G, Giulivi C, Dandekar S. PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 31740620 DOI: 10.1096/Fasebj.2020.34.S1.02382  0.336
2019 McMackin MZ, Durbin-Johnson B, Napierala M, Napierala JS, Ruiz L, Napoli E, Perlman S, Giulivi C, Cortopassi GA. Potential biomarker identification for Friedreich's ataxia using overlapping gene expression patterns in patient cells and mouse dorsal root ganglion. Plos One. 14: e0223209. PMID 31665133 DOI: 10.1371/journal.pone.0223209  0.332
2019 Jasoliya M, Sacca F, Sahdeo S, Chedin F, Pane C, Brescia Morra V, Filla A, Pook M, Cortopassi G. Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich's Ataxia. Plos One. 14: e0217776. PMID 31158268 DOI: 10.1371/Journal.Pone.0217776  0.333
2019 Sears TK, Datta S, Cortopassi G, Angelastro J, Woolard K. Abstract 3846: Targeting epigenetic dysregulation in isocitrate dehydrogenase mutant glioblastoma Cancer Research. 79: 3846-3846. DOI: 10.1158/1538-7445.Am2019-3846  0.318
2018 Bulkeley EA, Datta S, Cortopassi GA, Serafini R, Teague S, Varner DD, Meyers SA. Age-related Preferential Effects of Mitochondrial Oxidative Function on Progressive Motility and Decline of Mitochondrial Respiratory Capacity in Stallion Spermatozoa Journal of Equine Veterinary Science. 66: 35. DOI: 10.1016/J.Jevs.2018.05.014  0.362
2018 Cortopassi G. Mitochondria, Nrf2 and mTOR Free Radical Biology and Medicine. 128. DOI: 10.1016/J.Freeradbiomed.2018.10.382  0.537
2017 Teixeira J, Amorim R, Santos K, Soares P, Datta S, Cortopassi GA, Serafim TL, Sardão VA, Garrido J, Borges F, Oliveira PJ. Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative. Toxicology. PMID 29141199 DOI: 10.1016/j.tox.2017.11.014  0.4
2017 Yu AK, Datta S, McMackin MZ, Cortopassi GA. Rescue of cell death and inflammation of a mouse model of complex 1-mediated vision loss by repurposed drug molecules. Human Molecular Genetics. PMID 29040550 DOI: 10.1093/hmg/ddx373  0.375
2017 Hayashi G, Jasoliya M, Saccà F, Pane C, Filla A, Marsili A, Puorro G, Lanzillo R, Brescia Morra V, Cortopassi G. Dimethyl Fumarate Mediates Nrf2-dependent Mitochondrial Biogenesis in Mice and Humans. Human Molecular Genetics. PMID 28460056 DOI: 10.1093/hmg/ddx167  0.421
2017 Jasoliya MJ, McMackin MZ, Henderson CK, Perlman SL, Cortopassi GA. Frataxin Deficiency Impairs Mitochondrial Biogenesis in Cells, Mice and Humans. Human Molecular Genetics. PMID 28444186 DOI: 10.1093/hmg/ddx141  0.426
2016 Song L, McMackin M, Nguyen A, Cortopassi G. Parkin deficiency accelerates consequences of mitochondrial DNA deletions and Parkinsonism. Neurobiology of Disease. PMID 28042097 DOI: 10.1016/j.nbd.2016.12.024  0.346
2016 Song L, Yu A, Murray K, Cortopassi G. Bipolar cell reduction precedes retinal ganglion neuron loss in a complex 1 knockout mouse model. Brain Research. PMID 28027875 DOI: 10.1016/j.brainres.2016.12.019  0.374
2016 Datta S, Sahdeo S, Gray JA, Morriseau C, Hammock BD, Cortopassi G. A high-throughput screen for mitochondrial function reveals known and novel mitochondrial toxicants in a library of environmental agents. Mitochondrion. PMID 27717841 DOI: 10.1016/J.Mito.2016.10.001  0.358
2016 Datta S, Tomilov A, Cortopassi G. Identification of small molecules that improve ATP synthesis defects conferred by Leber's hereditary optic neuropathy mutations. Mitochondrion. PMID 27497748 DOI: 10.1016/j.mito.2016.08.002  0.403
2016 Darr CR, Varner DD, Teague S, Cortopassi GA, Datta S, Meyers SA. Lactate and Pyruvate Are Major Sources of Energy for Stallion Sperm with Dose Effects on Mitochondrial Function, Motility, and ROS Production. Biology of Reproduction. PMID 27335066 DOI: 10.1095/Biolreprod.116.140707  0.333
2016 Hayashi G, Cortopassi G. Lymphoblast Oxidative Stress Genes as Potential Biomarkers of Disease Severity and Drug Effect in Friedreich's Ataxia. Plos One. 11: e0153574. PMID 27078885 DOI: 10.1371/Journal.Pone.0153574  0.333
2016 Tomilov A, Tomilova N, Shan Y, Hagopian K, Bettaieb A, Kim K, Pelicci PG, Haj F, Ramsey J, Cortopassi G. The mitochondrial isoform of Shc protein inhibits thiolase and lipid oxidation. The Journal of Biological Chemistry. PMID 27059956 DOI: 10.1074/Jbc.M115.695577  0.362
2015 Shan Y, Cortopassi G. Mitochondrial Hspa9/Mortalin regulates erythroid differentiation via iron-sulfur cluster assembly. Mitochondrion. PMID 26702583 DOI: 10.1016/j.mito.2015.12.005  0.422
2015 Hayashi G, Cortopassi G. Oxidative stress in inherited mitochondrial diseases. Free Radical Biology & Medicine. 88: 10-7. PMID 26073122 DOI: 10.1016/j.freeradbiomed.2015.05.039  0.318
2015 Jin LW, Horiuchi M, Wulff H, Liu XB, Cortopassi GA, Erickson JD, Maezawa I. Dysregulation of glutamine transporter SNAT1 in Rett syndrome microglia: a mechanism for mitochondrial dysfunction and neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2516-29. PMID 25673846 DOI: 10.1523/Jneurosci.2778-14.2015  0.354
2014 Sahdeo S, Scott BD, McMackin MZ, Jasoliya M, Brown B, Wulff H, Perlman SL, Pook MA, Cortopassi GA. Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia. Human Molecular Genetics. 23: 6848-62. PMID 25113747 DOI: 10.1093/Hmg/Ddu408  0.322
2014 Hayashi G, Shen Y, Pedersen TL, Newman JW, Pook M, Cortopassi G. Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia. Human Molecular Genetics. 23: 6838-47. PMID 25104852 DOI: 10.1093/Hmg/Ddu407  0.407
2014 Sahdeo S, Tomilov A, Komachi K, Iwahashi C, Datta S, Hughes O, Hagerman P, Cortopassi G. High-throughput screening of FDA-approved drugs using oxygen biosensor plates reveals secondary mitofunctional effects. Mitochondrion. 17: 116-25. PMID 25034306 DOI: 10.1016/J.Mito.2014.07.002  0.367
2013 Fash DM, Khdour OM, Sahdeo SJ, Goldschmidt R, Jaruvangsanti J, Dey S, Arce PM, Collin VC, Cortopassi GA, Hecht SM. Effects of alkyl side chain modification of coenzyme Q10 on mitochondrial respiratory chain function and cytoprotection. Bioorganic & Medicinal Chemistry. 21: 2346-54. PMID 23473946 DOI: 10.1016/J.Bmc.2013.01.075  0.332
2013 Sahdeo S, Cortopassi G. Discovery of modulators of oxygen consumption for use in mitochondrial disease Mitochondrion. 13: 918. DOI: 10.1016/J.Mito.2013.07.053  0.431
2012 Chen L, Liu T, Tran A, Lu X, Tomilov AA, Davies V, Cortopassi G, Chiamvimonvat N, Bers DM, Votruba M, Knowlton AA. OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability. Journal of the American Heart Association. 1: e003012. PMID 23316298 DOI: 10.1161/Jaha.112.003012  0.518
2012 Song L, Shan Y, Lloyd KC, Cortopassi GA. Mutant Twinkle increases dopaminergic neurodegeneration, mtDNA deletions and modulates Parkin expression. Human Molecular Genetics. 21: 5147-58. PMID 22949510 DOI: 10.1093/hmg/dds365  0.311
2012 Shan Y, Cortopassi G. HSC20 interacts with frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis. Human Molecular Genetics. 21: 1457-69. PMID 22171070 DOI: 10.1093/hmg/ddr582  0.332
2012 Sahdeo S, Pook M, Napierala M, Sarsero J, Cortopassi G. Re-purposing small-molecule drugs to treat the mitochondrial disease Friedreich's ataxia Mitochondrion. 12: 571-572. DOI: 10.1016/J.Mito.2012.07.056  0.417
2011 Sahdeo S, Schoenfeld R, Cortopassi G. A high throughput screen for effectors of mitochondrial function Mitochondrion. 11: 641. DOI: 10.1016/J.Mito.2011.03.021  0.401
2010 Schoenfeld R, Wong A, Silva J, Li M, Itoh A, Horiuchi M, Itoh T, Pleasure D, Cortopassi G. Oligodendroglial differentiation induces mitochondrial genes and inhibition of mitochondrial function represses oligodendroglial differentiation. Mitochondrion. 10: 143-50. PMID 20005986 DOI: 10.1016/J.Mito.2009.12.141  0.522
2010 Chowanadisai W, Bauerly KA, Tchaparian E, Wong A, Cortopassi GA, Rucker RB. Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression. The Journal of Biological Chemistry. 285: 142-52. PMID 19861415 DOI: 10.1074/Jbc.M109.030130  0.375
2010 Schoenfeld R, Bach A, Cortopassi G. 143 Development of a cell based screening assay for drugs that alter mitochondrial function Mitochondrion. 10: 240. DOI: 10.1016/J.Mito.2009.12.134  0.418
2009 Silva JM, Wong A, Carelli V, Cortopassi GA. Inhibition of mitochondrial function induces an integrated stress response in oligodendroglia. Neurobiology of Disease. 34: 357-65. PMID 19233273 DOI: 10.1016/j.nbd.2009.02.005  0.425
2009 Rolo AP, Palmeira CM, Cortopassi GA. Biosensor plates detect mitochondrial physiological regulators and mutations in vivo. Analytical Biochemistry. 385: 176-8. PMID 18950600 DOI: 10.1016/j.ab.2008.10.002  0.433
2008 Silva JM, Wong A, Cortopassi GA. Mitochondrial inhibition induces PERK‐dependent activation of the unfolded protein response stress pathway in human oligodendroglial cells The Faseb Journal. 22: 303-303. DOI: 10.1096/FASEBJ.22.2_SUPPLEMENT.303  0.358
2008 Shan Y, Cortopassi G. S12.42 The frataxin-interacting protein grp75 chaperone plays an essential role in mitochondrial Fe/S cluster biogenesis Biochimica Et Biophysica Acta. 1777. DOI: 10.1016/J.Bbabio.2008.05.336  0.37
2008 Silva J, Cortopassi G. S9.6 lhon mutations and rotenone induce the unfolded protein response in human neural cells Biochimica Et Biophysica Acta. 1777. DOI: 10.1016/J.Bbabio.2008.05.221  0.393
2007 Prigione A, Cortopassi G. Mitochondrial DNA deletions induce the adenosine monophosphate-activated protein kinase energy stress pathway and result in decreased secretion of some proteins. Aging Cell. 6: 619-30. PMID 17651460 DOI: 10.1111/j.1474-9726.2007.00323.x  0.394
2007 Prigione A, Cortopassi G. Mitochondrial DNA deletions and chloramphenicol treatment stimulate the autophagic transcript ATG12. Autophagy. 3: 377-80. PMID 17457038  0.483
2007 Shan Y, Napoli E, Cortopassi G. Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones. Human Molecular Genetics. 16: 929-41. PMID 17331979 DOI: 10.1093/hmg/ddm038  0.388
2007 Alemi M, Prigione A, Wong A, Schoenfeld R, DiMauro S, Hirano M, Taroni F, Cortopassi G. Mitochondrial DNA deletions inhibit proteasomal activity and stimulate an autophagic transcript. Free Radical Biology & Medicine. 42: 32-43. PMID 17157191 DOI: 10.1016/j.freeradbiomed.2006.09.014  0.398
2007 Lu C, Cortopassi G. Frataxin knockdown causes loss of cytoplasmic iron-sulfur cluster functions, redox alterations and induction of heme transcripts. Archives of Biochemistry and Biophysics. 457: 111-22. PMID 17098208 DOI: 10.1016/j.abb.2006.09.010  0.353
2006 Cortopassi G, Danielson S, Alemi M, Zhan SS, Tong W, Carelli V, Martinuzzi A, Marzuki S, Majamaa K, Wong A. Mitochondrial disease activates transcripts of the unfolded protein response and cell cycle and inhibits vesicular secretion and oligodendrocyte-specific transcripts. Mitochondrion. 6: 161-75. PMID 16815102 DOI: 10.1016/J.Mito.2006.05.002  0.71
2006 Napoli E, Taroni F, Cortopassi GA. Frataxin, iron-sulfur clusters, heme, ROS, and aging. Antioxidants & Redox Signaling. 8: 506-16. PMID 16677095 DOI: 10.1089/ars.2006.8.506  0.414
2006 von Wurmb-Schwark N, Cavelier L, Cortopassi GA. A low dose of ethidium bromide leads to an increase of total mitochondrial DNA while higher concentrations induce the mtDNA 4997 deletion in a human neuronal cell line. Mutation Research. 596: 57-63. PMID 16488450 DOI: 10.1016/J.MRFMMM.2005.12.003  0.386
2005 Schoenfeld RA, Napoli E, Wong A, Zhan S, Reutenauer L, Morin D, Buckpitt AR, Taroni F, Lonnerdal B, Ristow M, Puccio H, Cortopassi GA. Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells. Human Molecular Genetics. 14: 3787-99. PMID 16239244 DOI: 10.1093/Hmg/Ddi393  0.454
2005 Danielson SR, Carelli V, Tan G, Martinuzzi A, Schapira AH, Savontaus ML, Cortopassi GA. Isolation of transcriptomal changes attributable to LHON mutations and the cybridization process. Brain : a Journal of Neurology. 128: 1026-37. PMID 15728653 DOI: 10.1093/Brain/Awh447  0.707
2003 Tan G, Napoli E, Taroni F, Cortopassi G. Decreased expression of genes involved in sulfur amino acid metabolism in frataxin-deficient cells. Human Molecular Genetics. 12: 1699-711. PMID 12837693  0.358
2002 Wong A, Cortopassi GA. High-throughput measurement of mitochondrial membrane potential in a neural cell line using a fluorescence plate reader. Biochemical and Biophysical Research Communications. 298: 750-4. PMID 12419317  0.394
2002 Cortopassi GA. A neutral theory predicts multigenic aging and increased concentrations of deleterious mutations on the mitochondrial and Y chromosomes. Free Radical Biology & Medicine. 33: 605-10. PMID 12208346  0.391
2002 Wong A, Cortopassi G. Reproducible quantitative PCR of mitochondrial and nuclear DNA copy number using the LightCycler. Methods in Molecular Biology (Clifton, N.J.). 197: 129-37. PMID 12013791 DOI: 10.1385/1-59259-284-8:129  0.425
2002 Wong A, Cavelier L, Collins-Schramm HE, Seldin MF, McGrogan M, Savontaus ML, Cortopassi GA. Differentiation-specific effects of LHON mutations introduced into neuronal NT2 cells. Human Molecular Genetics. 11: 431-8. PMID 11854175 DOI: 10.1093/Hmg/11.4.431  0.394
2002 Danielson SR, Wong A, Carelli V, Martinuzzi A, Schapira AH, Cortopassi GA. Cells bearing mutations causing Leber's hereditary optic neuropathy are sensitized to Fas-Induced apoptosis. The Journal of Biological Chemistry. 277: 5810-5. PMID 11741983 DOI: 10.1074/Jbc.M110119200  0.69
2001 Tan G, Chen LS, Lonnerdal B, Gellera C, Taroni FA, Cortopassi GA. Frataxin expression rescues mitochondrial dysfunctions in FRDA cells. Human Molecular Genetics. 10: 2099-107. PMID 11590127 DOI: 10.1093/Hmg/10.19.2099  0.338
2001 Sisemore MF, Zheng J, Yang JC, Thompson DA, Plopper CG, Cortopassi GA, Hammock BD. Cellular characterization of leukotoxin diol-induced mitochondrial dysfunction Archives of Biochemistry and Biophysics. 392: 32-37. PMID 11469791 DOI: 10.1006/Abbi.2001.2434  0.44
2001 Hutchin TP, Cortopassi GA. Mitochondrial defects and hearing loss. Cellular and Molecular Life Sciences : Cmls. 57: 1927-37. PMID 11215518 DOI: 10.1007/PL00000673  0.334
2000 Wong A, Yang J, Danielson S, Gellera C, Taroni F, Cortopassi G. Sensitivity of FRDA lymphoblasts to salts of transition metal ions. Antioxidants & Redox Signaling. 2: 461-5. PMID 11229359 DOI: 10.1089/15230860050192233  0.678
2000 Yang JC, Kahn A, Cortopassi G. Bcl-2 does not inhibit the permeability transition pore in mouse liver mitochondria. Toxicology. 151: 65-72. PMID 11074301 DOI: 10.1016/S0300-483X(00)00298-5  0.364
1999 Cortopassi GA, Wong A. Mitochondria in organismal aging and degeneration. Biochimica Et Biophysica Acta. 1410: 183-93. PMID 10076026 DOI: 10.1016/S0005-2728(98)00166-2  0.414
1999 Wong A, Yang J, Cavadini P, Gellera C, Lonnerdal B, Taroni F, Cortopassi G. The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis. Human Molecular Genetics. 8: 425-30. PMID 9949201 DOI: 10.1093/Hmg/8.3.425  0.375
1998 Goodell S, Cortopassi G. Analysis of oxygen consumption and mitochondrial permeability with age in mice. Mechanisms of Ageing and Development. 101: 245-56. PMID 9622228 DOI: 10.1016/S0047-6374(97)00182-6  0.347
1998 Yang JC, Cortopassi GA. Induction of the mitochondrial permeability transition causes release of the apoptogenic factor cytochrome c. Free Radical Biology & Medicine. 24: 624-31. PMID 9559874 DOI: 10.1016/S0891-5849(97)00367-5  0.371
1997 Wong A, Cortopassi G. mtDNA mutations confer cellular sensitivity to oxidant stress that is partially rescued by calcium depletion and cyclosporin A. Biochemical and Biophysical Research Communications. 239: 139-45. PMID 9345284 DOI: 10.1006/BBRC.1997.7443  0.379
1997 Wallace KB, Eells JT, Madeira VMC, Cortopassi G, Jones DP. Mitochondria-mediated cell injury Fundamental and Applied Toxicology. 38: 23-37. PMID 9268603 DOI: 10.1006/Faat.1997.2320  0.405
1997 Wang E, Wong A, Cortopassi G. The rate of mitochondrial mutagenesis is faster in mice than humans. Mutation Research. 377: 157-66. PMID 9247611 DOI: 10.1016/S0027-5107(97)00091-2  0.34
1997 Wallace KB, Eells JT, Madeira VMC, Cortopassi G, Jones DP. Mitochondria-Mediated Cell Injury Toxicological Sciences. 38: 23-37. DOI: 10.1093/Toxsci/38.1.23  0.405
1996 Murphy AN, Bredesen DE, Cortopassi G, Wang E, Fiskum G. Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria Proceedings of the National Academy of Sciences of the United States of America. 93: 9893-9898. PMID 8790427 DOI: 10.1073/Pnas.93.18.9893  0.333
1996 Cortopassi G, Liu Y, Hutchin T. Degeneration of human oncogenes and mitochondrial genes occurs in cells that exhibit age-related pathology. Experimental Gerontology. 31: 253-65. PMID 8706795 DOI: 10.1016/0531-5565(95)00021-6  0.387
1996 Hutchin TP, Wang E, Bredesen D, Cortopassi GA. A DICHOTOMY OF PROTECTION BY BCL-2 FROM MITOCHONDRIAL POISONS Biochemical Society Transactions. 24: 601S-601S. DOI: 10.1042/BST024601SC  0.402
1995 Hutchin T, Cortopassi G. Mitochondrial DNA haplotype predicts deafness risk American Journal of Medical Genetics. 60: 592-592. PMID 8825904 DOI: 10.1002/Ajmg.1320600623  0.428
1995 Hutchin T, Cortopassi G. A mitochondrial DNA clone is associated with increased risk for Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 92: 6892-5. PMID 7624338 DOI: 10.1073/PNAS.92.15.6892  0.339
1995 Cortopassi G, Wang E. Modelling the effects of age-related mtDNA mutation accumulation; complex I deficiency, superoxide and cell death. Biochimica Et Biophysica Acta. 1271: 171-6. PMID 7599205 DOI: 10.1016/0925-4439(95)00025-Y  0.43
1995 Cortopassi G, Liu Y. Genotypic selection of mitochondrial and oncogenic mutations in human tissue suggests mechanisms of age-related pathophysiology. Mutation Research. 338: 151-9. PMID 7565870 DOI: 10.1016/0921-8734(95)00020-7  0.389
1994 Cortopassi G, Hutchin T. A molecular and cellular hypothesis for aminoglycoside-induced deafness. Hearing Research. 78: 27-30. PMID 7961174 DOI: 10.1016/0378-5955(94)90040-X  0.322
1993 Prezant TR, Agapian JV, Bohlman MC, Bu X, Oztas S, Qiu WQ, Arnos KS, Cortopassi GA, Jaber L, Rotter JI. Mitochondrial ribosomal RNA mutation associated with both antibiotic-induced and non-syndromic deafness. Nature Genetics. 4: 289-94. PMID 7689389 DOI: 10.1038/NG0793-289  0.415
1992 Arnheim N, Cortopassi G. Deleterious mitochondrial DNA mutations accumulate in aging human tissues Mutation Research Dnaging. 275: 157-167. PMID 1383758 DOI: 10.1016/0921-8734(92)90020-P  0.477
1992 Soong NW, Hinton DR, Cortopassi G, Arnheim N. Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain. Nature Genetics. 2: 318-23. PMID 1303287 DOI: 10.1038/Ng1292-318  0.357
1990 Cortopassi GA, Arnheim N. Detection of a specific mitochondrial DNA deletion in tissues of older humans Nucleic Acids Research. 18: 6927-6933. PMID 2263455 DOI: 10.1093/Nar/18.23.6927  0.33
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