| Year |
Citation |
Score |
| 2021 |
Rogers RS, Parker A, Vainer PD, Elliott E, Sudbeck D, Parimi K, Peddada VP, Howe PG, D'Ambrosio N, Ruddy G, Stackable K, Carney M, Martin L, Osterholt T, Staudinger JL. The Interface between Cell Signaling Pathways and Pregnane X Receptor. Cells. 10. PMID 34831484 DOI: 10.3390/cells10113262 |
0.556 |
|
| 2020 |
Creamer BA, Sloan SNB, Dennis JF, Rogers R, Spencer S, McCuen A, Persaud P, Staudinger JL. Associations between Pregnane X Receptor and Breast Cancer Growth and Progression. Cells. 9. PMID 33076284 DOI: 10.3390/cells9102295 |
0.433 |
|
| 2020 |
Cui W, Shen X, Agbas E, Tompkins B, Cameron-Carter H, Staudinger J. Phosphorylation Modulates the Co-regulatory Protein Exchange of the Nuclear Receptor Pregnane X Receptor. The Journal of Pharmacology and Experimental Therapeutics. PMID 32205367 DOI: 10.1124/jpet.119.264762 |
0.571 |
|
| 2019 |
Staudinger JL. Clinical applications of small molecule inhibitors of Pregnane X receptor. Molecular and Cellular Endocrinology. PMID 30726709 DOI: 10.1016/j.mce.2019.02.002 |
0.478 |
|
| 2017 |
Staudinger JL. The Molecular Interface Between the SUMO and Ubiquitin Systems. Advances in Experimental Medicine and Biology. 963: 99-110. PMID 28197908 DOI: 10.1007/978-3-319-50044-7_6 |
0.412 |
|
| 2016 |
Cui W, Sun M, Zhang S, Shen X, Galeva N, Williams TD, Staudinger JL. A SUMO-acetyl switch in PXR Biology. Biochimica Et Biophysica Acta. PMID 26883953 DOI: 10.1016/J.Bbagrm.2016.02.008 |
0.818 |
|
| 2015 |
Cui W, Sun M, Galeva N, Williams TD, Azuma Y, Staudinger JL. SUMOylation and Ubiquitylation Circuitry Controls Pregnane X Receptor Biology in Hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1316-25. PMID 26063058 DOI: 10.1124/Dmd.115.065201 |
0.81 |
|
| 2015 |
Sun M, Cui W, Woody SK, Staudinger JL. Pregnane X receptor modulates the inflammatory response in primary cultures of hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 335-43. PMID 25527709 DOI: 10.1124/Dmd.114.062307 |
0.74 |
|
| 2014 |
Woody S, Staudinger J. Sumo-modification of pxr alters protein cofactor interactions (1062.11) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1062.11 |
0.636 |
|
| 2013 |
Staudinger JL, Woody S, Sun M, Cui W. Nuclear-receptor-mediated regulation of drug- and bile-acid-transporter proteins in gut and liver. Drug Metabolism Reviews. 45: 48-59. PMID 23330541 DOI: 10.3109/03602532.2012.748793 |
0.797 |
|
| 2011 |
Staudinger JL, Xu C, Biswas A, Mani S. Post-translational modification of pregnane x receptor. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 64: 4-10. PMID 21397695 DOI: 10.1016/J.Phrs.2011.02.011 |
0.804 |
|
| 2010 |
Hu G, Xu C, Staudinger JL. Pregnane X receptor is SUMOylated to repress the inflammatory response Journal of Pharmacology and Experimental Therapeutics. 335: 342-350. PMID 20719936 DOI: 10.1124/Jpet.110.171744 |
0.76 |
|
| 2010 |
Staudinger JL, Xu C, Cui YJ, Klaassen CD. Nuclear receptor-mediated regulation of carboxylesterase expression and activity. Expert Opinion On Drug Metabolism & Toxicology. 6: 261-71. PMID 20163318 DOI: 10.1517/17425250903483215 |
0.784 |
|
| 2009 |
Lichti-Kaiser K, Brobst D, Xu C, Staudinger JL. A systematic analysis of predicted phosphorylation sites within the human pregnane X receptor protein. The Journal of Pharmacology and Experimental Therapeutics. 331: 65-76. PMID 19617467 DOI: 10.1124/Jpet.109.157180 |
0.771 |
|
| 2009 |
Xu C, Wang X, Staudinger JL. Regulation of tissue-specific carboxylesterase expression by pregnane x receptor and constitutive androstane receptor. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1539-47. PMID 19359405 DOI: 10.1124/Dmd.109.026989 |
0.809 |
|
| 2009 |
Lichti-Kaiser K, Xu C, Staudinger JL. Cyclic AMP-dependent protein kinase signaling modulates pregnane x receptor activity in a species-specific manner. The Journal of Biological Chemistry. 284: 6639-49. PMID 19141612 DOI: 10.1074/Jbc.M807426200 |
0.79 |
|
| 2009 |
Singh RK, Dai Y, Staudinger JL, Muma NA. Activation of the JAK-STAT pathway is necessary for desensitization of 5-HT2A receptor-stimulated phospholipase C signalling by olanzapine, clozapine and MDL 100907. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 651-65. PMID 18976543 DOI: 10.1017/S1461145708009590 |
0.49 |
|
| 2008 |
Lichti-Kaiser K, Staudinger JL. The traditional Chinese herbal remedy tian xian activates pregnane X receptor and induces CYP3A gene expression in hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1538-45. PMID 18474680 DOI: 10.1124/Dmd.108.021774 |
0.821 |
|
| 2008 |
Staudinger JL. Liver-enriched nuclear receptors: therapeutic opportunities. Molecular Pharmaceutics. 5: 1-2. PMID 18247475 DOI: 10.1021/Mp700146B |
0.491 |
|
| 2008 |
Staudinger JL, Lichti K. Cell signaling and nuclear receptors: new opportunities for molecular pharmaceuticals in liver disease. Molecular Pharmaceutics. 5: 17-34. PMID 18159925 DOI: 10.1021/Mp700098C |
0.512 |
|
| 2006 |
Staudinger JL, Ding X, Lichti K. Pregnane X receptor and natural products: beyond drug-drug interactions. Expert Opinion On Drug Metabolism & Toxicology. 2: 847-57. PMID 17125405 DOI: 10.1517/17425255.2.6.847 |
0.782 |
|
| 2006 |
Ding X, Lichti K, Kim I, Gonzalez FJ, Staudinger JL. Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha. The Journal of Biological Chemistry. 281: 26540-51. PMID 16825189 DOI: 10.1074/Jbc.M600931200 |
0.791 |
|
| 2006 |
Ding X, Lichti K, Staudinger JL. The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 91: 448-55. PMID 16547076 DOI: 10.1093/Toxsci/Kfj163 |
0.837 |
|
| 2005 |
Ding X, Staudinger JL. The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter. The Journal of Pharmacology and Experimental Therapeutics. 314: 120-7. PMID 15833898 DOI: 10.1124/Jpet.105.085225 |
0.809 |
|
| 2005 |
Ding X, Staudinger JL. Repression of PXR-mediated induction of hepatic CYP3A gene expression by protein kinase C. Biochemical Pharmacology. 69: 867-73. PMID 15710363 DOI: 10.1016/J.Bcp.2004.11.025 |
0.817 |
|
| 2005 |
Ding X, Staudinger JL. Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway. The Journal of Pharmacology and Experimental Therapeutics. 312: 849-56. PMID 15459237 DOI: 10.1124/Jpet.104.076331 |
0.816 |
|
| 2004 |
Brobst DE, Ding X, Creech KL, Goodwin B, Kelley B, Staudinger JL. Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor. The Journal of Pharmacology and Experimental Therapeutics. 310: 528-35. PMID 15075359 DOI: 10.1124/Jpet.103.064329 |
0.821 |
|
| 2003 |
Chen C, Staudinger JL, Klaassen CD. Nuclear receptor, pregname X receptor, is required for induction of UDP-glucuronosyltranferases in mouse liver by pregnenolone-16 alpha-carbonitrile. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 908-15. PMID 12814968 DOI: 10.1124/Dmd.31.7.908 |
0.438 |
|
| 2003 |
Staudinger JL, Madan A, Carol KM, Parkinson A. Regulation of drug transporter gene expression by nuclear receptors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 523-7. PMID 12695338 DOI: 10.1124/Dmd.31.5.523 |
0.467 |
|
| 2002 |
McInvale AC, Staudinger J, Harlan RE, Garcia MM. Immunolocalization of PICK1 in the ascending auditory pathways of the adult rat. The Journal of Comparative Neurology. 450: 382-94. PMID 12209850 DOI: 10.1002/Cne.10328 |
0.365 |
|
| 2002 |
Guo GL, Staudinger J, Ogura K, Klaassen CD. Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16alpha-carbonitrile is via interaction with pregnane X receptor. Molecular Pharmacology. 61: 832-9. PMID 11901222 DOI: 10.1124/Mol.61.4.832 |
0.434 |
|
| 2001 |
Torres GE, Yao WD, Mohn AR, Quan H, Kim KM, Levey AI, Staudinger J, Caron MG. Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron. 30: 121-34. PMID 11343649 DOI: 10.1016/S0896-6273(01)00267-7 |
0.334 |
|
| 1998 |
Torres R, Firestein BL, Dong H, Staudinger J, Olson EN, Huganir RL, Bredt DS, Gale NW, Yancopoulos GD. PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands. Neuron. 21: 1453-63. PMID 9883737 DOI: 10.1016/S0896-6273(00)80663-7 |
0.491 |
|
| 1998 |
Yan ZH, Karam WG, Staudinger JL, Medvedev A, Ghanayem BI, Jetten AM. Regulation of peroxisome proliferator-activated receptor alpha-induced transactivation by the nuclear orphan receptor TAK1/TR4. The Journal of Biological Chemistry. 273: 10948-57. PMID 9556573 DOI: 10.1074/JBC.273.18.10948 |
0.488 |
|
| 1998 |
Kliewer SA, Moore JT, Wade L, Staudinger JL, Watson MA, Jones SA, McKee DD, Oliver BB, Willson TM, Zetterström RH, Perlmann T, Lehmann JM. An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway. Cell. 92: 73-82. PMID 9489701 DOI: 10.1016/S0092-8674(00)80900-9 |
0.498 |
|
| 1998 |
Wu SL, Staudinger J, Olson EN, Rubin CS. Structure, expression, and properties of an atypical protein kinase C (PKC3) from Caenorhabditis elegans. PKC3 is required for the normal progression of embryogenesis and viability of the organism. The Journal of Biological Chemistry. 273: 1130-43. PMID 9422779 DOI: 10.1074/Jbc.273.2.1130 |
0.377 |
|
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