| Year |
Citation |
Score |
| 2024 |
Joshi D, Coon BG, Chakraborty R, Deng H, Fernandez-Tussy P, Meredith E, Traylor JG, Orr AW, Fernandez-Hernando C, Schwartz MA. Gamma protocadherins in vascular endothelial cells inhibit Klf2/4 to promote atherosclerosis. Biorxiv : the Preprint Server For Biology. PMID 38293157 DOI: 10.1101/2024.01.16.575958 |
0.52 |
|
| 2021 |
Driscoll TP, Bidone TC, Ahn SJ, Yu A, Groisman A, Voth GA, Schwartz MA. Integrin-Based Mechanosensing through Conformational Deformation. Biophysical Journal. PMID 34509509 DOI: 10.1016/j.bpj.2021.09.010 |
0.586 |
|
| 2021 |
Deng H, Min E, Baeyens N, Coon BG, Hu R, Zhuang ZW, Chen M, Huang B, Afolabi T, Zarkada G, Acheampong A, McEntee K, Eichmann A, Liu F, Su B, ... ... Schwartz MA, et al. Activation of Smad2/3 signaling by low fluid shear stress mediates artery inward remodeling. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34504019 DOI: 10.1073/pnas.2105339118 |
0.322 |
|
| 2021 |
Abou Ziki MD, Bhat N, Neogi A, Driscoll TP, Ugwu N, Liu Y, Smith E, Abboud JM, Chouairi S, Schwartz MA, Akar JG, Mani A. Epistatic interaction of PDE4DIP and DES mutations in familial atrial fibrillation with slow conduction. Human Mutation. PMID 34289528 DOI: 10.1002/humu.24265 |
0.517 |
|
| 2021 |
Park H, Furtado J, Poulet M, Chung M, Yun S, Lee S, Sessa WC, Franco CA, Schwartz MA, Eichmann A. Defective Flow-Migration Coupling Causes Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. Circulation. PMID 34182767 DOI: 10.1161/CIRCULATIONAHA.120.053047 |
0.328 |
|
| 2020 |
Driscoll TP, Ahn SJ, Huang B, Kumar A, Schwartz MA. Actin flow-dependent and -independent force transmission through integrins. Proceedings of the National Academy of Sciences of the United States of America. PMID 33262280 DOI: 10.1073/pnas.2010292117 |
0.607 |
|
| 2020 |
Shin EY, Park JH, You ST, Lee CS, Won SY, Park JJ, Kim HB, Shim J, Soung NK, Lee OJ, Schwartz MA, Kim EG. Integrin-mediated adhesions in regulation of cellular senescence. Science Advances. 6: eaay3909. PMID 32494696 DOI: 10.1126/Sciadv.Aay3909 |
0.413 |
|
| 2020 |
Chen PY, Schwartz MA, Simons M. Endothelial-to-Mesenchymal Transition, Vascular Inflammation, and Atherosclerosis. Frontiers in Cardiovascular Medicine. 7: 53. PMID 32478094 DOI: 10.3389/Fcvm.2020.00053 |
0.323 |
|
| 2020 |
Schwartz M. Mechanotransduction through Integrin‐mediated Adhesions The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00148 |
0.331 |
|
| 2019 |
Yun S, Hu R, Schwaemmle ME, Scherer AN, Zhuang Z, Koleske AJ, Pallas DC, Schwartz MA. Integrin α5β1 regulates PP2A complex assembly through PDE4D in atherosclerosis. The Journal of Clinical Investigation. 130. PMID 31408443 DOI: 10.1172/Jci127692 |
0.418 |
|
| 2019 |
Kumar A, Shutova MS, Tanaka K, Iwamoto DV, Calderwood DA, Svitkina TM, Schwartz MA. Filamin A mediates isotropic distribution of applied force across the actin network. The Journal of Cell Biology. PMID 31315944 DOI: 10.1083/Jcb.201901086 |
0.323 |
|
| 2019 |
RamÍrez CM, Zhang X, Bandyopadhyay C, Rotllan N, Sugiyama MG, Aryal B, Liu X, He S, Kraehling JR, Ulrich V, Lin CS, Velazquez H, Lasunción MA, Li G, Suárez Y, ... Schwartz MA, et al. Caveolin-1 Regulates Atherogenesis by Attenuating LDL Transcytosis and Vascular Inflammation Independent of Endothelial Nitric Oxide Synthase Activation. Circulation. PMID 31154825 DOI: 10.1161/Circulationaha.118.038571 |
0.318 |
|
| 2019 |
Hu X, Liu ZZ, Chen X, Schulz VP, Kumar A, Hartman AA, Weinstein J, Johnston JF, Rodriguez EC, Eastman AE, Cheng J, Min L, Zhong M, Carroll C, Gallagher PG, ... Schwartz M, et al. MKL1-actin pathway restricts chromatin accessibility and prevents mature pluripotency activation. Nature Communications. 10: 1695. PMID 30979898 DOI: 10.1038/S41467-019-09636-6 |
0.381 |
|
| 2019 |
Bidone TC, Polley A, Jin J, Driscoll T, Iwamoto DV, Calderwood DA, Schwartz MA, Voth GA. Coarse-Grained Simulation of Full-Length Integrin Activation. Biophysical Journal. PMID 30851876 DOI: 10.1016/J.Bpj.2019.02.011 |
0.583 |
|
| 2019 |
Moro A, Driscoll TP, Boraas LC, Armero W, Kasper DM, Baeyens N, Jouy C, Mallikarjun V, Swift J, Ahn SJ, Lee D, Zhang J, Gu M, Gerstein M, Schwartz M, et al. MicroRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis. Nature Cell Biology. PMID 30742093 DOI: 10.1038/S41556-019-0272-Y |
0.613 |
|
| 2019 |
Min E, Schwartz MA. Translocating transcription factors in fluid shear stress-mediated vascular remodeling and disease. Experimental Cell Research. PMID 30633880 DOI: 10.1016/J.Yexcr.2019.01.005 |
0.421 |
|
| 2019 |
Lay AJ, Coleman PR, Formaz-Preston A, Ting KK, Roediger B, Weninger W, Schwartz MA, Vadas MA, Gamble JR. ARHGAP18: A Flow-Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis. Journal of the American Heart Association. 8: e010057. PMID 30630384 DOI: 10.1161/Jaha.118.010057 |
0.394 |
|
| 2019 |
Driscoll TP, Huang B, Ahn SJ, Kumar A, Schwartz M. Actin Flow Dependent and Independent Force Transmission in Integrin-Mediated Adhesions Biophysical Journal. 116: 123a. DOI: 10.1016/J.Bpj.2018.11.684 |
0.641 |
|
| 2018 |
Rosowski KA, Boltyanskiy R, Xiang Y, Van den Dries K, Schwartz MA, Dufresne ER. Vinculin and the mechanical response of adherent fibroblasts to matrix deformation. Scientific Reports. 8: 17967. PMID 30568231 DOI: 10.1038/S41598-018-36272-9 |
0.353 |
|
| 2018 |
Kumar A, Anderson KL, Swift MF, Hanein D, Volkmann N, Schwartz MA. Local Tension on Talin in Focal Adhesions Correlates with F-Actin Alignment at the Nanometer Scale. Biophysical Journal. PMID 30274833 DOI: 10.1016/J.Bpj.2018.08.045 |
0.347 |
|
| 2018 |
Goult BT, Yan J, Schwartz MA. Talin as a mechanosensitive signaling hub. The Journal of Cell Biology. PMID 30254032 DOI: 10.1083/Jcb.201808061 |
0.354 |
|
| 2018 |
Di Modugno F, Spada S, Palermo B, Visca P, Iapicca P, Di Carlo A, Antoniani B, Sperduti I, Di Benedetto A, Terrenato I, Mottolese M, Gandolfi F, Facciolo F, Chen EI, Schwartz MA, et al. hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis. Oncogene. PMID 29907768 DOI: 10.1038/S41388-018-0364-3 |
0.341 |
|
| 2018 |
Fang JS, Coon BG, Gillis N, Chen Z, Qiu J, Chittenden TW, Burt JM, Schwartz MA, Hirschi KK. Addendum: Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Nature Communications. 9: 720. PMID 29445140 DOI: 10.1038/S41467-018-03076-4 |
0.331 |
|
| 2018 |
Budatha M, Zhang J, Zhuang ZW, Yun S, Dahlman JE, Anderson DG, Schwartz MA. Inhibiting Integrin α5 Cytoplasmic Domain Signaling Reduces Atherosclerosis and Promotes Arteriogenesis. Journal of the American Heart Association. 7. PMID 29382667 DOI: 10.1161/Jaha.117.007501 |
0.361 |
|
| 2018 |
Modugno FD, Spada S, Palermo B, Visca P, Iapicca P, Carlo AD, Antoniani B, Sperduti I, Benedetto AD, Terrenato I, Mottolese M, Gandolfi F, Facciolo F, Chen E, Schwartz MA, et al. Abstract 5224: hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis Cancer Research. 78: 5224-5224. DOI: 10.1158/1538-7445.Am2018-5224 |
0.351 |
|
| 2018 |
Bidone TC, Driscoll T, Schwartz MA, Voth GA. Integrin-Based Mechanosensing is Mediated by Conformational Activation Biophysical Journal. 114: 21a. DOI: 10.1016/J.Bpj.2017.11.160 |
0.609 |
|
| 2017 |
Fang JS, Coon BG, Gillis N, Chen Z, Qiu J, Chittenden TW, Burt JM, Schwartz MA, Hirschi KK. Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Nature Communications. 8: 2149. PMID 29247167 DOI: 10.1038/S41467-017-01742-7 |
0.373 |
|
| 2017 |
Lagendijk AK, Gomez GA, Baek S, Hesselson D, Hughes WE, Paterson S, Conway DE, Belting HG, Affolter M, Smith KA, Schwartz MA, Yap AS, Hogan BM. Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish. Nature Communications. 8: 1402. PMID 29123087 DOI: 10.1038/S41467-017-01325-6 |
0.353 |
|
| 2017 |
Conway DE, Coon BG, Budatha M, Arsenovic PT, Orsenigo F, Wessel F, Zhang J, Zhuang Z, Dejana E, Vestweber D, Schwartz MA. VE-Cadherin Phosphorylation Regulates Endothelial Fluid Shear Stress Responses through the Polarity Protein LGN. Current Biology : Cb. 27: 2727. PMID 28898639 DOI: 10.1016/J.Cub.2017.08.064 |
0.339 |
|
| 2017 |
Conway DE, Coon BG, Budatha M, Arsenovic PT, Orsenigo F, Wessel F, Zhang J, Zhuang Z, Dejana E, Vestweber D, Schwartz MA. VE-Cadherin Phosphorylation Regulates Endothelial Fluid Shear Stress Responses through the Polarity Protein LGN. Current Biology : Cb. PMID 28712573 DOI: 10.1016/J.Cub.2017.06.020 |
0.467 |
|
| 2017 |
Bosco DB, Roycik MD, Jin Y, Schwartz MA, Lively TJ, Zorio DA, Sang QA. A new synthetic matrix metalloproteinase inhibitor reduces human mesenchymal stem cell adipogenesis. Plos One. 12: e0172925. PMID 28234995 DOI: 10.1371/Journal.Pone.0172925 |
0.324 |
|
| 2016 |
Wang Y, Baeyens N, Corti F, Tanaka K, Fang JS, Zhang J, Jin Y, Coon B, Hirschi KK, Schwartz MA, Simons M. Syndecan-4 controls lymphatic vasculature remodeling during embryonic development. Development (Cambridge, England). PMID 27789626 DOI: 10.1242/Dev.140129 |
0.399 |
|
| 2016 |
Baeyens N, Larrivée B, Ola R, Hayward-Piatkowskyi B, Dubrac A, Huang B, Ross TD, Coon BG, Min E, Tsarfati M, Tong H, Eichmann A, Schwartz MA. Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia. The Journal of Cell Biology. PMID 27646277 DOI: 10.1083/Jcb.201603106 |
0.438 |
|
| 2016 |
Yun S, Budatha M, Dahlman JE, Coon BG, Cameron RT, Langer R, Anderson DG, Baillie G, Schwartz MA. Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling. Nature Cell Biology. PMID 27595237 DOI: 10.1038/Ncb3405 |
0.408 |
|
| 2016 |
Gerhold KA, Schwartz MA. Ion Channels in Endothelial Responses to Fluid Shear Stress. Physiology (Bethesda, Md.). 31: 359-69. PMID 27511462 DOI: 10.1152/Physiol.00007.2016 |
0.332 |
|
| 2016 |
Chen Y, Lee H, Tong H, Schwartz M, Zhu C. Force regulated conformational change of integrin αVβ3. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27423389 DOI: 10.1016/J.Matbio.2016.07.002 |
0.351 |
|
| 2016 |
Balestrini JL, Gard AL, Gerhold KA, Wilcox EC, Liu A, Schwan J, Le AV, Baevova P, Dimitrievska S, Zhao L, Sundaram S, Sun H, Rittié L, Dyal R, Broekelmann TJ, ... ... Schwartz MA, et al. Comparative biology of decellularized lung matrix: Implications of species mismatch in regenerative medicine. Biomaterials. 102: 220-230. PMID 27344365 DOI: 10.1016/J.Biomaterials.2016.06.025 |
0.301 |
|
| 2016 |
Pawar A, Meier JA, Dasgupta A, Diwanji N, Deshpande N, Saxena K, Buwa N, Inchanalkar S, Schwartz MA, Balasubramanian N. Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling. Cellular Signalling. PMID 27269287 DOI: 10.1016/J.Cellsig.2016.05.023 |
0.416 |
|
| 2016 |
Kumar A, Ouyang M, Van den Dries K, McGhee EJ, Tanaka K, Anderson MD, Groisman A, Goult BT, Anderson KI, Schwartz MA. Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity. The Journal of Cell Biology. 213: 371-83. PMID 27161398 DOI: 10.1083/Jcb.201510012 |
0.347 |
|
| 2016 |
Baeyens N, Bandyopadhyay C, Coon BG, Yun S, Schwartz MA. Endothelial fluid shear stress sensing in vascular health and disease. The Journal of Clinical Investigation. 126: 821-8. PMID 26928035 DOI: 10.1172/Jci83083 |
0.402 |
|
| 2016 |
Baeyens N, Schwartz MA. Biomechanics of vascular mechanosensation and remodeling. Molecular Biology of the Cell. 27: 7-11. PMID 26715421 DOI: 10.1091/Mbc.E14-11-1522 |
0.373 |
|
| 2015 |
Dubrac A, Genet G, Ola R, Zhang F, Pibouin-Fragner L, Han J, Zhang J, Thomas JL, Chedotal A, Schwartz MA, Eichmann A. Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neo-Vascularization. Circulation. PMID 26659946 DOI: 10.1161/Circulationaha.115.017537 |
0.339 |
|
| 2015 |
Cuttano R, Rudini N, Bravi L, Corada M, Giampietro C, Papa E, Morini MF, Maddaluno L, Baeyens N, Adams RH, Jain MK, Owens GK, Schwartz M, Lampugnani MG, Dejana E. KLF4 is a key determinant in the development and progression of cerebral cavernous malformations. Embo Molecular Medicine. PMID 26612856 DOI: 10.15252/Emmm.201505433 |
0.361 |
|
| 2015 |
Chen PY, Qin L, Baeyens N, Li G, Afolabi T, Budatha M, Tellides G, Schwartz MA, Simons M. Endothelial-to-mesenchymal transition drives atherosclerosis progression. The Journal of Clinical Investigation. 2015. PMID 26517696 DOI: 10.1172/Jci82719 |
0.354 |
|
| 2015 |
Humphrey JD, Schwartz MA, Tellides G, Milewicz DM. Role of mechanotransduction in vascular biology: focus on thoracic aortic aneurysms and dissections. Circulation Research. 116: 1448-61. PMID 25858068 DOI: 10.1161/Circresaha.114.304936 |
0.318 |
|
| 2015 |
Coon BG, Baeyens N, Han J, Budatha M, Ross TD, Fang JS, Yun S, Thomas JL, Schwartz MA. Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. The Journal of Cell Biology. 208: 975-86. PMID 25800053 DOI: 10.1083/jcb.201408103 |
0.382 |
|
| 2015 |
Tornavaca O, Chia M, Dufton N, Almagro LO, Conway DE, Randi AM, Schwartz MA, Matter K, Balda MS. ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation. The Journal of Cell Biology. 208: 821-38. PMID 25753039 DOI: 10.1083/Jcb.201404140 |
0.398 |
|
| 2015 |
Baeyens N, Nicoli S, Coon BG, Ross TD, Van den Dries K, Han J, Lauridsen HM, Mejean CO, Eichmann A, Thomas JL, Humphrey JD, Schwartz MA. Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point. Elife. 4. PMID 25643397 DOI: 10.7554/Elife.04645 |
0.354 |
|
| 2015 |
Daneshjou N, Sieracki N, van Nieuw Amerongen GP, Schwartz MA, Komarova YA, Malik AB, Conway DE. Rac1 functions as a reversible tension modulator to stabilize VE-cadherin trans-interaction. The Journal of Cell Biology. 208: 23-32. PMID 25559184 DOI: 10.1083/Jcb.201409108 |
0.388 |
|
| 2015 |
Bancroft T, Bouaouina M, Roberts S, Lee M, Calderwood DA, Schwartz M, Simons M, Sessa WC, Kyriakides TR. Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function. The Journal of Biological Chemistry. 290: 409-22. PMID 25389299 DOI: 10.1074/Jbc.M114.618421 |
0.346 |
|
| 2015 |
Mohamied Y, Rowland EM, Bailey EL, Sherwin SJ, Schwartz MA, Weinberg PD. Change of direction in the biomechanics of atherosclerosis. Annals of Biomedical Engineering. 43: 16-25. PMID 25138165 DOI: 10.1007/S10439-014-1095-4 |
0.312 |
|
| 2014 |
Moissoglu K, Schwartz MA. Spatial and temporal control of Rho GTPase functions. Cellular Logistics. 4: e943618. PMID 25610718 DOI: 10.4161/21592780.2014.943618 |
0.327 |
|
| 2014 |
Conway DE, Schwartz MA. Mechanotransduction of shear stress occurs through changes in VE-cadherin and PECAM-1 tension: Implications for cell migration. Cell Adhesion & Migration. 1-5. PMID 25482618 DOI: 10.4161/19336918.2014.968498 |
0.432 |
|
| 2014 |
Baeyens N, Mulligan-Kehoe MJ, Corti F, Simon DD, Ross TD, Rhodes JM, Wang TZ, Mejean CO, Simons M, Humphrey J, Schwartz MA. Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling. Proceedings of the National Academy of Sciences of the United States of America. 111: 17308-13. PMID 25404299 DOI: 10.1073/Pnas.1413725111 |
0.421 |
|
| 2014 |
Humphrey JD, Dufresne ER, Schwartz MA. Mechanotransduction and extracellular matrix homeostasis. Nature Reviews. Molecular Cell Biology. 15: 802-12. PMID 25355505 DOI: 10.1038/Nrm3896 |
0.334 |
|
| 2014 |
Morrison AR, Yarovinsky TO, Young BD, Moraes F, Ross TD, Ceneri N, Zhang J, Zhuang ZW, Sinusas AJ, Pardi R, Schwartz MA, Simons M, Bender JR. Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis. The Journal of Experimental Medicine. 211: 1957-68. PMID 25180062 DOI: 10.1084/Jem.20132130 |
0.384 |
|
| 2014 |
Leerberg JM, Gomez GA, Verma S, Moussa EJ, Wu SK, Priya R, Hoffman BD, Grashoff C, Schwartz MA, Yap AS. Tension-sensitive actin assembly supports contractility at the epithelial zonula adherens. Current Biology : Cb. 24: 1689-99. PMID 25065757 DOI: 10.1016/J.Cub.2014.06.028 |
0.314 |
|
| 2014 |
Humphrey JD, Milewicz DM, Tellides G, Schwartz MA. Cell biology. Dysfunctional mechanosensing in aneurysms. Science (New York, N.Y.). 344: 477-9. PMID 24786066 DOI: 10.1126/Science.1253026 |
0.408 |
|
| 2014 |
Moissoglu K, Kiessling V, Wan C, Hoffman BD, Norambuena A, Tamm LK, Schwartz MA. Regulation of Rac1 translocation and activation by membrane domains and their boundaries. Journal of Cell Science. 127: 2565-76. PMID 24695858 DOI: 10.1242/Jcs.149088 |
0.551 |
|
| 2013 |
Conway DE, Schwartz MA. Flow-dependent cellular mechanotransduction in atherosclerosis. Journal of Cell Science. 126: 5101-9. PMID 24190880 DOI: 10.1242/Jcs.138313 |
0.321 |
|
| 2013 |
Wang C, Baker BM, Chen CS, Schwartz MA. Endothelial cell sensing of flow direction. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2130-6. PMID 23814115 DOI: 10.1161/Atvbaha.113.301826 |
0.426 |
|
| 2013 |
Ross TD, Coon BG, Yun S, Baeyens N, Tanaka K, Ouyang M, Schwartz MA. Integrins in mechanotransduction. Current Opinion in Cell Biology. 25: 613-8. PMID 23797029 DOI: 10.1016/J.Ceb.2013.05.006 |
0.372 |
|
| 2013 |
Conway DE, Breckenridge MT, Hinde E, Gratton E, Chen CS, Schwartz MA. Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Current Biology : Cb. 23: 1024-30. PMID 23684974 DOI: 10.1016/J.Cub.2013.04.049 |
0.45 |
|
| 2013 |
Ouyang M, Lu S, Kim T, Chen CE, Seong J, Leckband DE, Wang F, Reynolds AB, Schwartz MA, Wang Y. N-cadherin regulates spatially polarized signals through distinct p120ctn and β-catenin-dependent signalling pathways. Nature Communications. 4: 1589. PMID 23481397 DOI: 10.1038/Ncomms2560 |
0.362 |
|
| 2012 |
Tirziu D, Jaba IM, Yu P, Larrivée B, Coon BG, Cristofaro B, Zhuang ZW, Lanahan AA, Schwartz MA, Eichmann A, Simons M. Endothelial nuclear factor-κB-dependent regulation of arteriogenesis and branching. Circulation. 126: 2589-600. PMID 23091063 DOI: 10.1161/Circulationaha.112.119321 |
0.337 |
|
| 2012 |
Simons M, Schwartz MA. Profilin phosphorylation as a VEGFR effector in angiogenesis. Nature Cell Biology. 14: 985-7. PMID 23033049 DOI: 10.1038/Ncb2596 |
0.336 |
|
| 2012 |
Jhaveri KA, Debnath P, Chernoff J, Sanders J, Schwartz MA. The role of p21-activated kinase in the initiation of atherosclerosis. Bmc Cardiovascular Disorders. 12: 55. PMID 22824149 DOI: 10.1186/1471-2261-12-55 |
0.393 |
|
| 2012 |
Wang C, Lu H, Schwartz MA. A novel in vitro flow system for changing flow direction on endothelial cells. Journal of Biomechanics. 45: 1212-8. PMID 22386042 DOI: 10.1016/J.Jbiomech.2012.01.045 |
0.387 |
|
| 2012 |
Schwartz MA, Simons M. Lymphatics thrive on stress: mechanical force in lymphatic development. The Embo Journal. 31: 781-2. PMID 22334045 DOI: 10.1038/Emboj.2011.484 |
0.316 |
|
| 2012 |
Batra N, Burra S, Siller-Jackson AJ, Gu S, Xia X, Weber GF, DeSimone D, Bonewald LF, Lafer EM, Sprague E, Schwartz MA, Jiang JX. Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels. Proceedings of the National Academy of Sciences of the United States of America. 109: 3359-64. PMID 22331870 DOI: 10.1073/Pnas.1115967109 |
0.664 |
|
| 2012 |
Conway D, Schwartz MA. Lessons from the endothelial junctional mechanosensory complex. F1000 Biology Reports. 4: 1. PMID 22238515 DOI: 10.3410/B4-1 |
0.386 |
|
| 2011 |
Hahn C, Wang C, Orr AW, Coon BG, Schwartz MA. JNK2 promotes endothelial cell alignment under flow. Plos One. 6: e24338. PMID 21909388 DOI: 10.1371/Journal.Pone.0024338 |
0.818 |
|
| 2011 |
Norambuena A, Schwartz MA. Effects of integrin-mediated cell adhesion on plasma membrane lipid raft components and signaling. Molecular Biology of the Cell. 22: 3456-64. PMID 21795400 DOI: 10.1091/Mbc.E11-04-0361 |
0.37 |
|
| 2011 |
Hoffman BD, Grashoff C, Schwartz MA. Dynamic molecular processes mediate cellular mechanotransduction. Nature. 475: 316-23. PMID 21776077 DOI: 10.1038/Nature10316 |
0.342 |
|
| 2011 |
Goguen BN, Hoffman BD, Sellers JR, Schwartz MA, Imperiali B. Light-triggered myosin activation for probing dynamic cellular processes. Angewandte Chemie (International Ed. in English). 50: 5667-70. PMID 21542072 DOI: 10.1002/Anie.201100674 |
0.402 |
|
| 2011 |
Schwartz MA. Super-resolution microscopy: a new dimension in focal adhesions. Current Biology : Cb. 21: R115-6. PMID 21300274 DOI: 10.1016/J.Cub.2010.12.025 |
0.312 |
|
| 2011 |
Thomas S, Overdevest JB, Nitz MD, Williams PD, Owens CR, Sanchez-Carbayo M, Frierson HF, Schwartz MA, Theodorescu D. Src and caveolin-1 reciprocally regulate metastasis via a common downstream signaling pathway in bladder cancer. Cancer Research. 71: 832-41. PMID 21148751 DOI: 10.1158/0008-5472.Can-10-0730 |
0.373 |
|
| 2010 |
Schwartz MA. Integrins and extracellular matrix in mechanotransduction. Cold Spring Harbor Perspectives in Biology. 2: a005066. PMID 21084386 DOI: 10.1101/Cshperspect.A005066 |
0.389 |
|
| 2010 |
Parsons JT, Horwitz AR, Schwartz MA. Cell adhesion: integrating cytoskeletal dynamics and cellular tension. Nature Reviews. Molecular Cell Biology. 11: 633-43. PMID 20729930 DOI: 10.1038/Nrm2957 |
0.669 |
|
| 2010 |
Lee CS, Choi CK, Shin EY, Schwartz MA, Kim EG. Myosin II directly binds and inhibits Dbl family guanine nucleotide exchange factors: a possible link to Rho family GTPases. The Journal of Cell Biology. 190: 663-74. PMID 20713598 DOI: 10.1083/Jcb.201003057 |
0.416 |
|
| 2010 |
Shin ME, He Y, Li D, Na S, Chowdhury F, Poh YC, Collin O, Su P, de Lanerolle P, Schwartz MA, Wang N, Wang F. Spatiotemporal organization, regulation, and functions of tractions during neutrophil chemotaxis. Blood. 116: 3297-310. PMID 20616216 DOI: 10.1182/Blood-2009-12-260851 |
0.396 |
|
| 2010 |
Grashoff C, Hoffman BD, Brenner MD, Zhou R, Parsons M, Yang MT, McLean MA, Sligar SG, Chen CS, Ha T, Schwartz MA. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature. 466: 263-6. PMID 20613844 DOI: 10.1038/Nature09198 |
0.325 |
|
| 2010 |
Feaver RE, Gelfand BD, Wang C, Schwartz MA, Blackman BR. Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation. Circulation Research. 106: 1703-11. PMID 20378855 DOI: 10.1161/Circresaha.109.216283 |
0.451 |
|
| 2010 |
Funk SD, Yurdagul A, Green JM, Jhaveri KA, Schwartz MA, Orr AW. Matrix-specific protein kinase A signaling regulates p21-activated kinase activation by flow in endothelial cells. Circulation Research. 106: 1394-403. PMID 20224042 DOI: 10.1161/Circresaha.109.210286 |
0.82 |
|
| 2010 |
Schwartz MA. Remembrance of dead cells past: discovering that the extracellular matrix is a cell survival factor. Molecular Biology of the Cell. 21: 499-500. PMID 20150528 DOI: 10.1091/Mbc.E09-07-0602 |
0.343 |
|
| 2010 |
Balasubramanian N, Meier JA, Scott DW, Norambuena A, White MA, Schwartz MA. RalA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Current Biology : Cb. 20: 75-9. PMID 20005108 DOI: 10.1016/J.Cub.2009.11.016 |
0.365 |
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| 2010 |
Thomas S, Overdevest JB, Nitz M, Williams P, Schwartz MA, Theodorescu D. Abstract 5130: Src and Caveolin-1 reciprocally regulate metastasis via Rho Kinase Cancer Research. 70: 5130-5130. DOI: 10.1158/1538-7445.Am10-5130 |
0.355 |
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| 2009 |
Petzold T, Orr AW, Hahn C, Jhaveri KA, Parsons JT, Schwartz MA. Focal adhesion kinase modulates activation of NF-kappaB by flow in endothelial cells. American Journal of Physiology. Cell Physiology. 297: C814-22. PMID 19587216 DOI: 10.1152/Ajpcell.00226.2009 |
0.798 |
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| 2009 |
Elfenbein A, Rhodes JM, Meller J, Schwartz MA, Matsuda M, Simons M. Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway. The Journal of Cell Biology. 186: 75-83. PMID 19581409 DOI: 10.1083/Jcb.200810179 |
0.381 |
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| 2009 |
Wu Y, Moissoglu K, Wang H, Wang X, Frierson HF, Schwartz MA, Theodorescu D. Src phosphorylation of RhoGDI2 regulates its metastasis suppressor function. Proceedings of the National Academy of Sciences of the United States of America. 106: 5807-12. PMID 19321744 DOI: 10.1073/Pnas.0810094106 |
0.333 |
|
| 2009 |
Dzamba BJ, Jakab KR, Marsden M, Schwartz MA, DeSimone DW. Cadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization. Developmental Cell. 16: 421-32. PMID 19289087 DOI: 10.1016/J.Devcel.2009.01.008 |
0.676 |
|
| 2009 |
Hahn C, Orr AW, Sanders JM, Jhaveri KA, Schwartz MA. The subendothelial extracellular matrix modulates JNK activation by flow. Circulation Research. 104: 995-1003. PMID 19286608 DOI: 10.1161/Circresaha.108.186486 |
0.811 |
|
| 2009 |
Moissoglu K, McRoberts KS, Meier JA, Theodorescu D, Schwartz MA. Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. Cancer Research. 69: 2838-44. PMID 19276387 DOI: 10.1158/0008-5472.Can-08-1397 |
0.345 |
|
| 2009 |
Hahn C, Schwartz MA. Mechanotransduction in vascular physiology and atherogenesis. Nature Reviews. Molecular Cell Biology. 10: 53-62. PMID 19197332 DOI: 10.1038/Nrm2596 |
0.782 |
|
| 2009 |
Schwartz MA. Cell biology. The force is with us. Science (New York, N.Y.). 323: 588-9. PMID 19179515 DOI: 10.1126/Science.1169414 |
0.336 |
|
| 2009 |
Sebbagh M, Santoni MJ, Hall B, Borg JP, Schwartz MA. Regulation of LKB1/STRAD localization and function by E-cadherin. Current Biology : Cb. 19: 37-42. PMID 19110428 DOI: 10.1016/J.Cub.2008.11.033 |
0.353 |
|
| 2008 |
Schwartz MA, McRoberts K, Coyner M, Andarawewa KL, Frierson HF, Sanders JM, Swenson S, Markland F, Conaway MR, Theodorescu D. Integrin agonists as adjuvants in chemotherapy for melanoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 6193-7. PMID 18829498 DOI: 10.1158/1078-0432.Ccr-08-1285 |
0.32 |
|
| 2008 |
Hahn C, Schwartz MA. The role of cellular adaptation to mechanical forces in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2101-7. PMID 18787190 DOI: 10.1161/Atvbaha.108.165951 |
0.784 |
|
| 2008 |
Harry BL, Sanders JM, Feaver RE, Lansey M, Deem TL, Zarbock A, Bruce AC, Pryor AW, Gelfand BD, Blackman BR, Schwartz MA, Ley K. Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2003-8. PMID 18688018 DOI: 10.1161/Atvbaha.108.164707 |
0.369 |
|
| 2008 |
Orr AW, Hahn C, Blackman BR, Schwartz MA. p21-activated kinase signaling regulates oxidant-dependent NF-kappa B activation by flow. Circulation Research. 103: 671-9. PMID 18669917 DOI: 10.1161/Circresaha.108.182097 |
0.804 |
|
| 2008 |
Schwartz MA, DeSimone DW. Cell adhesion receptors in mechanotransduction. Current Opinion in Cell Biology. 20: 551-6. PMID 18583124 DOI: 10.1016/J.Ceb.2008.05.005 |
0.681 |
|
| 2008 |
Meller J, Vidali L, Schwartz MA. Endogenous RhoG is dispensable for integrin-mediated cell spreading but contributes to Rac-independent migration. Journal of Cell Science. 121: 1981-9. PMID 18505794 DOI: 10.1242/Jcs.025130 |
0.461 |
|
| 2008 |
Hall B, McLean MA, Davis K, Casanova JE, Sligar SG, Schwartz MA. A fluorescence resonance energy transfer activation sensor for Arf6. Analytical Biochemistry. 374: 243-9. PMID 18162163 DOI: 10.1016/J.Ab.2007.11.032 |
0.331 |
|
| 2008 |
Hall B, McLean MA, Davis K, Casanova JE, Sligar SG, Schwartz MA. A FRET Activation Sensor for Arf6 Analytical Biochemistry. 374: 243. DOI: 10.1016/J.Ab.2007.11.03 |
0.353 |
|
| 2007 |
Balasubramanian N, Scott DW, Castle JD, Casanova JE, Schwartz MA. Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts. Nature Cell Biology. 9: 1381-91. PMID 18026091 DOI: 10.1038/Ncb1657 |
0.348 |
|
| 2007 |
Stockton R, Reutershan J, Scott D, Sanders J, Ley K, Schwartz MA. Induction of vascular permeability: beta PIX and GIT1 scaffold the activation of extracellular signal-regulated kinase by PAK. Molecular Biology of the Cell. 18: 2346-55. PMID 17429073 DOI: 10.1091/Mbc.E06-07-0584 |
0.412 |
|
| 2007 |
Del Pozo MA, Schwartz MA. Rac, membrane heterogeneity, caveolin and regulation of growth by integrins. Trends in Cell Biology. 17: 246-50. PMID 17363257 DOI: 10.1016/J.Tcb.2007.03.001 |
0.396 |
|
| 2007 |
Reutershan J, Stockton R, Zarbock A, Sullivan GW, Chang D, Scott D, Schwartz MA, Ley K. Blocking p21-activated kinase reduces lipopolysaccharide-induced acute lung injury by preventing polymorphonuclear leukocyte infiltration. American Journal of Respiratory and Critical Care Medicine. 175: 1027-35. PMID 17322107 DOI: 10.1164/Rccm.200612-1822Oc |
0.34 |
|
| 2007 |
Orr AW, Stockton R, Simmers MB, Sanders JM, Sarembock IJ, Blackman BR, Schwartz MA. Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis. The Journal of Cell Biology. 176: 719-27. PMID 17312022 DOI: 10.1083/Jcb.200609008 |
0.631 |
|
| 2007 |
Hahn C, Orr AW, Sanders JM, Sarembock IJ, Schwartz MA. Matrix‐Specific JNK Activation by Flow The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A269-A |
0.781 |
|
| 2007 |
Orr AW, Stockton R, Simmers M, Sanders JM, Blackman BR, Schwartz MA. Matrix‐specific PAK activation regulates vascular permeability in atherosclerosis The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A268-D |
0.556 |
|
| 2006 |
Gaus K, Le Lay S, Balasubramanian N, Schwartz MA. Integrin-mediated adhesion regulates membrane order. The Journal of Cell Biology. 174: 725-34. PMID 16943184 DOI: 10.1083/Jcb.200603034 |
0.347 |
|
| 2006 |
Orr AW, Ginsberg MH, Shattil SJ, Deckmyn H, Schwartz MA. Matrix-specific suppression of integrin activation in shear stress signaling. Molecular Biology of the Cell. 17: 4686-97. PMID 16928957 DOI: 10.1091/Mbc.E06-04-0289 |
0.651 |
|
| 2006 |
Moissoglu K, Schwartz MA. Integrin signalling in directed cell migration Biology of the Cell. 98: 547-555. PMID 16907663 DOI: 10.1042/Bc20060025 |
0.387 |
|
| 2006 |
Schwartz MA, Horwitz AR. Integrating adhesion, protrusion, and contraction during cell migration. Cell. 125: 1223-5. PMID 16814706 DOI: 10.1016/J.Cell.2006.06.015 |
0.641 |
|
| 2006 |
Sang QX, Jin Y, Newcomer RG, Monroe SC, Fang X, Hurst DR, Lee S, Cao Q, Schwartz MA. Matrix metalloproteinase inhibitors as prospective agents for the prevention and treatment of cardiovascular and neoplastic diseases. Current Topics in Medicinal Chemistry. 6: 289-316. PMID 16611144 DOI: 10.2174/156802606776287045 |
0.302 |
|
| 2006 |
Orr AW, Helmke BP, Blackman BR, Schwartz MA. Mechanisms of mechanotransduction. Developmental Cell. 10: 11-20. PMID 16399074 DOI: 10.1016/J.Devcel.2005.12.006 |
0.511 |
|
| 2006 |
Schwartz MA, Yap AS. Cell-to-cell contact and extracellular matrix Current Opinion in Cell Biology. 18: 461-462. DOI: 10.1016/J.Ceb.2006.08.013 |
0.334 |
|
| 2005 |
de Rooij J, Kerstens A, Danuser G, Schwartz MA, Waterman-Storer CM. Integrin-dependent actomyosin contraction regulates epithelial cell scattering. The Journal of Cell Biology. 171: 153-64. PMID 16216928 DOI: 10.1083/Jcb.200506152 |
0.378 |
|
| 2005 |
Bolick DT, Orr AW, Whetzel A, Srinivasan S, Hatley ME, Schwartz MA, Hedrick CC. 12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 2301-7. PMID 16166569 DOI: 10.1161/01.Atv.0000186181.19909.A6 |
0.594 |
|
| 2005 |
Tzima E, Irani-Tehrani M, Kiosses WB, Dejana E, Schultz DA, Engelhardt B, Cao G, DeLisser H, Schwartz MA. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature. 437: 426-31. PMID 16163360 DOI: 10.1038/Nature03952 |
0.469 |
|
| 2005 |
del Pozo MA, Balasubramanian N, Alderson NB, Kiosses WB, Grande-García A, Anderson RG, Schwartz MA. Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization. Nature Cell Biology. 7: 901-8. PMID 16113676 DOI: 10.1038/Ncb1293 |
0.388 |
|
| 2005 |
Hurst DR, Schwartz MA, Jin Y, Ghaffari MA, Kozarekar P, Cao J, Sang QX. Inhibition of enzyme activity of and cell-mediated substrate cleavage by membrane type 1 matrix metalloproteinase by newly developed mercaptosulphide inhibitors. The Biochemical Journal. 392: 527-36. PMID 16026329 DOI: 10.1042/Bj20050545 |
0.319 |
|
| 2005 |
Titus B, Schwartz MA, Theodorescu D. Rho proteins in cell migration and metastasis. Critical Reviews in Eukaryotic Gene Expression. 15: 103-14. PMID 16022631 DOI: 10.1615/Critreveukaryotgeneexpr.V15.I2.20 |
0.336 |
|
| 2005 |
Orr AW, Sanders JM, Bevard M, Coleman E, Sarembock IJ, Schwartz MA. The subendothelial extracellular matrix modulates NF-kappaB activation by flow: a potential role in atherosclerosis. The Journal of Cell Biology. 169: 191-202. PMID 15809308 DOI: 10.1083/Jcb.200410073 |
0.63 |
|
| 2005 |
Katsumi A, Naoe T, Matsushita T, Kaibuchi K, Schwartz MA. Integrin activation and matrix binding mediate cellular responses to mechanical stretch. The Journal of Biological Chemistry. 280: 16546-9. PMID 15760908 DOI: 10.1074/Jbc.C400455200 |
0.43 |
|
| 2005 |
Civelekoglu-Scholey G, Orr AW, Novak I, Meister JJ, Schwartz MA, Mogilner A. Model of coupled transient changes of Rac, Rho, adhesions and stress fibers alignment in endothelial cells responding to shear stress. Journal of Theoretical Biology. 232: 569-85. PMID 15588637 DOI: 10.1016/J.Jtbi.2004.09.004 |
0.57 |
|
| 2005 |
Tzima E, Reader JS, Irani-Tehrani M, Ewalt KL, Schwartz MA, Schimmel P. VE-cadherin links tRNA synthetase cytokine to anti-angiogenic function. The Journal of Biological Chemistry. 280: 2405-8. PMID 15579907 DOI: 10.1074/Jbc.C400431200 |
0.358 |
|
| 2005 |
Katsumi A, Matsushita T, Naoe T, Schwartz MA. αvβ3 Integrin Activation and Matrix Binding Mediate Cellular Responses to Mechanical Stretch. Blood. 106: 3689-3689. DOI: 10.1182/Blood.V106.11.3689.3689 |
0.423 |
|
| 2004 |
Schwartz M. Rho signalling at a glance Journal of Cell Science. 117: 5457-5458. PMID 15509861 DOI: 10.1242/Jcs.01582 |
0.384 |
|
| 2004 |
Stockton RA, Schaefer E, Schwartz MA. p21-activated kinase regulates endothelial permeability through modulation of contractility. The Journal of Biological Chemistry. 279: 46621-30. PMID 15333633 DOI: 10.1074/Jbc.M408877200 |
0.439 |
|
| 2004 |
Meller N, Irani-Tehrani M, Ratnikov BI, Paschal BM, Schwartz MA. The novel Cdc42 guanine nucleotide exchange factor, zizimin1, dimerizes via the Cdc42-binding CZH2 domain. The Journal of Biological Chemistry. 279: 37470-6. PMID 15247287 DOI: 10.1074/Jbc.M404535200 |
0.327 |
|
| 2004 |
Shiu YT, Li S, Marganski WA, Usami S, Schwartz MA, Wang YL, Dembo M, Chien S. Rho mediates the shear-enhancement of endothelial cell migration and traction force generation. Biophysical Journal. 86: 2558-65. PMID 15041692 DOI: 10.1016/S0006-3495(04)74311-8 |
0.415 |
|
| 2004 |
Katsumi A, Orr AW, Tzima E, Schwartz MA. Integrins in mechanotransduction. The Journal of Biological Chemistry. 279: 12001-4. PMID 14960578 DOI: 10.1074/Jbc.R300038200 |
0.56 |
|
| 2004 |
del Pozo MA, Alderson NB, Kiosses WB, Chiang HH, Anderson RG, Schwartz MA. Integrins regulate Rac targeting by internalization of membrane domains. Science (New York, N.Y.). 303: 839-42. PMID 14764880 DOI: 10.1126/Science.1092571 |
0.342 |
|
| 2004 |
Schlunck G, Damke H, Kiosses WB, Rusk N, Symons MH, Waterman-Storer CM, Schmid SL, Schwartz MA. Modulation of Rac localization and function by dynamin. Molecular Biology of the Cell. 15: 256-67. PMID 14617821 DOI: 10.1091/Mbc.E03-01-0019 |
0.429 |
|
| 2004 |
Tzima E, Irani-Tehrani M, Dejana E, Schwartz M. ROLE OF CELL-CELL JUNCTIONS IN MEDIATING ENDOTHELIAL CELL RESPONSES TO FLUID SHEAR STRESS Cardiovascular Pathology. 13: 41. DOI: 10.1016/J.Carpath.2004.03.115 |
0.361 |
|
| 2003 |
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. Cell migration: integrating signals from front to back. Science (New York, N.Y.). 302: 1704-9. PMID 14657486 DOI: 10.1126/Science.1092053 |
0.636 |
|
| 2003 |
Tzima E, Reader JS, Irani-Tehrani M, Ewalt KL, Schwartz MA, Schimmel P. Biologically active fragment of a human tRNA synthetase inhibits fluid shear stress-activated responses of endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 14903-7. PMID 14630953 DOI: 10.1073/Pnas.2436330100 |
0.427 |
|
| 2003 |
Hood JD, Frausto R, Kiosses WB, Schwartz MA, Cheresh DA. Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis. The Journal of Cell Biology. 162: 933-43. PMID 12952943 DOI: 10.1083/Jcb.200304105 |
0.346 |
|
| 2003 |
Truong T, Sun G, Doorly M, Wang JY, Schwartz MA. Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl. Proceedings of the National Academy of Sciences of the United States of America. 100: 10281-6. PMID 12928501 DOI: 10.1073/Pnas.1635435100 |
0.342 |
|
| 2003 |
Lin T, Zeng L, Liu Y, DeFea K, Schwartz MA, Chien S, Shyy JY. Rho-ROCK-LIMK-cofilin pathway regulates shear stress activation of sterol regulatory element binding proteins. Circulation Research. 92: 1296-304. PMID 12775580 DOI: 10.1161/01.Res.0000078780.65824.8B |
0.428 |
|
| 2003 |
Tzima E, Kiosses WB, del Pozo MA, Schwartz MA. Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress. The Journal of Biological Chemistry. 278: 31020-3. PMID 12754216 DOI: 10.1074/Jbc.M301179200 |
0.464 |
|
| 2003 |
del Pozo MA, Schwartz MA, Hu J, Kiosses WB, Altman A, Villalba M. Guanine exchange-dependent and -independent effects of Vav1 on integrin-induced T cell spreading. Journal of Immunology (Baltimore, Md. : 1950). 170: 41-7. PMID 12496381 DOI: 10.4049/Jimmunol.170.1.41 |
0.378 |
|
| 2002 |
Tzima E, Del Pozo MA, Kiosses WB, Mohamed SA, Li S, Chien S, Schwartz MA. Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression. The Embo Journal. 21: 6791-800. PMID 12486000 DOI: 10.1093/Emboj/Cdf688 |
0.449 |
|
| 2002 |
Meller N, Irani-Tehrani M, Kiosses WB, Del Pozo MA, Schwartz MA. Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins. Nature Cell Biology. 4: 639-47. PMID 12172552 DOI: 10.1038/Ncb835 |
0.352 |
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| 2002 |
Katsumi A, Milanini J, Kiosses WB, del Pozo MA, Kaunas R, Chien S, Hahn KM, Schwartz MA. Effects of cell tension on the small GTPase Rac. The Journal of Cell Biology. 158: 153-64. PMID 12105187 DOI: 10.1083/Jcb.200201105 |
0.421 |
|
| 2002 |
Schwartz MA, Ginsberg MH. Networks and crosstalk: integrin signalling spreads. Nature Cell Biology. 4: E65-8. PMID 11944032 DOI: 10.1038/Ncb0402-E65 |
0.302 |
|
| 2002 |
Kiosses WB, Hood J, Yang S, Gerritsen ME, Cheresh DA, Alderson N, Schwartz MA. A dominant-negative p65 PAK peptide inhibits angiogenesis. Circulation Research. 90: 697-702. PMID 11934838 DOI: 10.1161/01.Res.0000014227.76102.5D |
0.302 |
|
| 2002 |
Lewis JM, Truong TN, Schwartz MA. Integrins regulate the apoptotic response to DNA damage through modulation of p53. Proceedings of the National Academy of Sciences of the United States of America. 99: 3627-32. PMID 11904424 DOI: 10.1073/Pnas.062698499 |
0.304 |
|
| 2002 |
Del Pozo MA, Kiosses WB, Alderson NB, Meller N, Hahn KM, Schwartz MA. Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI. Nature Cell Biology. 4: 232-9. PMID 11862216 DOI: 10.1038/Ncb759 |
0.367 |
|
| 2002 |
Blaber SI, Scarisbrick IA, Bernett MJ, Dhanarajan P, Seavy MA, Jin Y, Schwartz MA, Rodriguez M, Blaber M. Enzymatic properties of rat myelencephalon-specific protease. Biochemistry. 41: 1165-73. PMID 11802715 DOI: 10.1021/Bi015781A |
0.324 |
|
| 2001 |
Calderwood DA, Huttenlocher A, Kiosses WB, Rose DM, Woodside DG, Schwartz MA, Ginsberg MH. Increased filamin binding to β-integrin cytoplasmic domains inhibits cell migration Nature Cell Biology. 3: 1060-1068. PMID 11781567 DOI: 10.1038/Ncb1201-1060 |
0.365 |
|
| 2001 |
Schwartz MA. Integrin signaling revisited Trends in Cell Biology. 11: 466-470. PMID 11719050 DOI: 10.1016/S0962-8924(01)02152-3 |
0.357 |
|
| 2001 |
Nguyen BP, Ren X, Schwartz MA, Carter WG. Ligation of Integrin α3β1 by Laminin 5 at the Wound Edge Activates Rho-dependent Adhesion of Leading Keratinocytes on Collagen Journal of Biological Chemistry. 276: 43860-43870. PMID 11571278 DOI: 10.1074/Jbc.M103404200 |
0.396 |
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| 2001 |
Tzima E, Del Pozo MA, Shattil SJ, Chien S, Schwartz MA. Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment Embo Journal. 20: 4639-4647. PMID 11532928 DOI: 10.1093/Emboj/20.17.4639 |
0.462 |
|
| 2001 |
Sun J, Zhao J, Schwartz MA, Wang JY, Wiedmer T, Sims PJ. c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1. The Journal of Biological Chemistry. 276: 28984-90. PMID 11390389 DOI: 10.1074/Jbc.M102505200 |
0.338 |
|
| 2001 |
Kiosses WB, Shattil SJ, Pampori N, Schwartz MA. Rac recruits high-affinity integrin αvβ3 to lamellipodia in endothelial cell migration Nature Cell Biology. 3: 316-320. PMID 11231584 DOI: 10.1038/35060120 |
0.366 |
|
| 2001 |
Assoian RK, Schwartz MA. Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression Current Opinion in Genetics and Development. 11: 48-53. PMID 11163150 DOI: 10.1016/S0959-437X(00)00155-6 |
0.355 |
|
| 2001 |
Baron V, Schwartz M. Cell adhesion regulates ubiquitin-mediated degradation of the platelet-derived growth factor receptor beta. The Journal of Biological Chemistry. 275: 39318-23. PMID 11007771 DOI: 10.1074/Jbc.M003618200 |
0.372 |
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| 2001 |
Jalali S, del Pozo MA, Chen K, Miao H, Li Y, Schwartz MA, Shyy JYJ, Chien S. Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands Proceedings of the National Academy of Sciences. 98: 1042-1046. DOI: 10.1073/Pnas.98.3.1042 |
0.391 |
|
| 2000 |
Plopper GE, Huff JL, Rust WL, Schwartz MA, Quaranta V. Antibody-induced activation of β1 integrin receptors stimulates cAMP-dependent migration of breast cells on laminin-5 Molecular Cell Biology Research Communications. 4: 129-135. PMID 11170844 DOI: 10.1006/Mcbr.2001.0267 |
0.361 |
|
| 2000 |
Ren XD, Schwartz MA. Determination of GTP loading on Rho Methods in Enzymology. 325: 264-272. PMID 11036609 DOI: 10.1016/S0076-6879(00)25448-7 |
0.326 |
|
| 2000 |
Kraynov VS, Chamberlain C, Bokoch GM, Schwartz MA, Slabaugh S, Hahn KM. Localized Rac activation dynamics visualized in living cells. Science (New York, N.Y.). 290: 333-7. PMID 11030651 DOI: 10.1126/Science.290.5490.333 |
0.377 |
|
| 2000 |
Ramos JW, Hughes PE, Renshaw MW, Schwartz MA, Formstecher E, Chneiweiss H, Ginsberg MH. Death effector domain protein PEA-15 potentiates Ras activation of extracellular signal receptor-activated kinase by an adhesion-independent mechanism. Molecular Biology of the Cell. 11: 2863-72. PMID 10982386 DOI: 10.1091/Mbc.11.9.2863 |
0.377 |
|
| 2000 |
Adams JC, Schwartz MA. Stimulation of fascin spikes by thrombospondin-1 is mediated by the GTPases Rac and Cdc42 Journal of Cell Biology. 150: 807-822. PMID 10953005 DOI: 10.1083/Jcb.150.4.807 |
0.428 |
|
| 2000 |
Jia MC, Schwartz MA, Sang QA. Suppression of human microvascular endothelial cell invasion and morphogenesis with synthetic matrixin inhibitors: Targeting angiogenesis with MMP inhibitors Advances in Experimental Medicine and Biology. 476: 181-194. PMID 10949665 DOI: 10.1007/978-1-4615-4221-6_15 |
0.327 |
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| 2000 |
Sang QA, Jia M, Schwartz MA, Jaye MC, Kleinman HK, Ghaffari MA, Luo Y. New thiol and sulfodiimine metalloproteinase inhibitors and their effect on human microvascular endothelial cell growth. Biochemical and Biophysical Research Communications. 274: 780-786. PMID 10924354 DOI: 10.1006/Bbrc.2000.3212 |
0.331 |
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| 2000 |
Renshaw MW, Lewis JM, Schwartz MA. The c-Abl tyrosine kinase contributes to the transient activation of MAP kinase in cells plated on fibronectin. Oncogene. 19: 3216-3219. PMID 10918577 DOI: 10.1038/Sj.Onc.1203667 |
0.357 |
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| 2000 |
Schwartz MA, Shattil SJ. Signaling networks linking integrins and rho family GTPases. Trends in Biochemical Sciences. 25: 388-391. PMID 10916159 DOI: 10.1016/S0968-0004(00)01605-4 |
0.364 |
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| 2000 |
Pozo MAd, Price LS, Alderson NB, Ren X, Schwartz MA. Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK. The Embo Journal. 19: 2008-2014. PMID 10790367 DOI: 10.1093/Emboj/19.9.2008 |
0.424 |
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| 1999 |
Kiosses WB, Daniels RH, Otey C, Bokoch GM, Schwartz MA. A role for p21-activated kinase in endothelial cell migration Journal of Cell Biology. 147: 831-843. PMID 10562284 DOI: 10.1083/Jcb.147.4.831 |
0.431 |
|
| 1999 |
Renshaw MW, Price LS, Schwartz MA. Focal Adhesion Kinase Mediates the Integrin Signaling Requirement for Growth Factor Activation of Map Kinase Journal of Cell Biology. 147: 611-618. PMID 10545504 DOI: 10.1083/Jcb.147.3.611 |
0.377 |
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| 1999 |
Yron I, Deckert M, Reff ME, Munshi A, Schwartz MA, Altman A. Integrin-dependent tyrosine phosphorylation and growth regulation by Vav. Cell Adhesion and Communication. 7: 1-11. PMID 10228731 DOI: 10.3109/15419069909034388 |
0.41 |
|
| 1999 |
Schwartz MA, Baron V. Interactions between mitogenic stimuli, or, a thousand and one connections Current Opinion in Cell Biology. 11: 197-202. PMID 10209147 DOI: 10.1016/S0955-0674(99)80026-X |
0.338 |
|
| 1999 |
Meredith JE, Kiosses WB, Takada Y, Schwartz MA. Mutational analysis of cell cycle inhibition by integrin beta1C. The Journal of Biological Chemistry. 274: 8111-6. PMID 10075712 DOI: 10.1074/Jbc.274.12.8111 |
0.324 |
|
| 1999 |
Ren X, Kiosses WB, Schwartz MA. Regulation of the small GTP‐binding protein Rho by cell adhesion and the cytoskeleton The Embo Journal. 18: 578-585. PMID 9927417 DOI: 10.1093/Emboj/18.3.578 |
0.446 |
|
| 1998 |
Schwartz MA, Meredith JE, Kiosses WB. An activated Rac mutant functions as a dominant negative for membrane ruffling. Oncogene. 17: 625-9. PMID 9704928 DOI: 10.1038/Sj.Onc.1201977 |
0.341 |
|
| 1998 |
Price LS, Leng J, Schwartz MA, Bokoch GM. Activation of Rac and Cdc42 by Integrins Mediates Cell Spreading Molecular Biology of the Cell. 9: 1863-1871. PMID 9658176 DOI: 10.1091/Mbc.9.7.1863 |
0.459 |
|
| 1998 |
Lewis JM, Schwartz MA. Integrins regulate the association and phosphorylation of paxillin by c- Abl Journal of Biological Chemistry. 273: 14225-14230. PMID 9603926 DOI: 10.1074/Jbc.273.23.14225 |
0.385 |
|
| 1998 |
Ren XD, Schwartz MA. Regulation of inositol lipid kinases by Rho and Rac Current Opinion in Genetics and Development. 8: 63-67. PMID 9529607 DOI: 10.1016/S0959-437X(98)80063-4 |
0.322 |
|
| 1997 |
Meredith JE, Schwartz MA. Integrins, adhesion and apoptosis. Trends in Cell Biology. 7: 146-50. PMID 17708932 DOI: 10.1016/S0962-8924(97)01002-7 |
0.38 |
|
| 1997 |
Schwartz MA. Integrins, oncogenes, and anchorage independence Journal of Cell Biology. 139: 575-578. PMID 9348275 DOI: 10.1083/Jcb.139.3.575 |
0.372 |
|
| 1997 |
Renshaw MW, Ren X, Schwartz MA. Growth factor activation of MAP kinase requires cell adhesion. The Embo Journal. 16: 5592-5599. PMID 9312018 DOI: 10.1093/Emboj/16.18.5592 |
0.386 |
|
| 1997 |
Kreisberg JI, Ghosh-Choudhury N, Radnik RA, Schwartz MA. Role of Rho and myosin phosphorylation in actin stress fiber assembly in mesangial cells. American Journal of Physiology-Renal Physiology. 273. PMID 9277589 DOI: 10.1152/Ajprenal.1997.273.2.F283 |
0.345 |
|
| 1997 |
Hughes PE, Renshaw MW, Pfaff M, Forsyth J, Keivens VM, Schwartz MA, Ginsberg MH. Suppression of integrin activation: a novel function of a Ras/Raf-initiated MAP kinase pathway. Cell. 88: 521-30. PMID 9038343 DOI: 10.1016/S0092-8674(00)81892-9 |
0.369 |
|
| 1996 |
Lewis JM, Baskaran R, Taagepera S, Schwartz MA, Wang JY. Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport. Proceedings of the National Academy of Sciences of the United States of America. 93: 15174-9. PMID 8986783 DOI: 10.1073/Pnas.93.26.15174 |
0.375 |
|
| 1996 |
Ren XD, Bokoch GM, Traynor-Kaplan A, Jenkins GH, Anderson RA, Schwartz MA. Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol 4-phosphate 5-kinase in Swiss 3T3 cells. Molecular Biology of the Cell. 7: 435-442. PMID 8868471 DOI: 10.1091/Mbc.7.3.435 |
0.349 |
|
| 1996 |
Meredith JE, Winitz S, Lewis JM, Hess S, Ren XD, Renshaw MW, Schwartz MA. The regulation of growth and intracellular signaling by integrins. Endocrine Reviews. 17: 207-20. PMID 8771356 DOI: 10.1210/Edrv-17-3-207 |
0.342 |
|
| 1996 |
Renshaw MW, Toksoz D, Schwartz MA. Involvement of the Small GTPase Rho in Integrin-mediated Activation of Mitogen-activated Protein Kinase Journal of Biological Chemistry. 271: 21691-21694. PMID 8702960 DOI: 10.1074/Jbc.271.36.21691 |
0.39 |
|
| 1996 |
Schwartz MA, Toksoz D, Khosravi-Far R. Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway. The Embo Journal. 15: 6525-6530. DOI: 10.1002/J.1460-2075.1996.Tb01043.X |
0.365 |
|
| 1995 |
Schwartz MA, Schaller MD, Ginsberg MH. Integrins: Emerging paradigms of signal transduction Annual Review of Cell and Developmental Biology. 11: 549-599. PMID 8689569 DOI: 10.1146/Annurev.Cb.11.110195.003001 |
0.348 |
|
| 1994 |
Schwartz MA, Ingber DE. Integrating with integrins. Molecular Biology of the Cell. 5: 389-93. PMID 8054683 DOI: 10.1091/Mbc.5.4.389 |
0.328 |
|
| 1994 |
Chong LD, Traynor-Kaplan A, Bokoch GM, Schwartz MA. The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell. 79: 507-513. PMID 7954816 DOI: 10.1016/0092-8674(94)90259-3 |
0.388 |
|
| 1994 |
Schwartz MA, Denninghoff K. Alpha v integrins mediate the rise in intracellular calcium in endothelial cells on fibronectin even though they play a minor role in adhesion. Journal of Biological Chemistry. 269: 11133-11137. DOI: 10.1074/Jbc.270.50.30235 |
0.312 |
|
| 1993 |
McNamee HP, Ingber DE, Schwartz MA. Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown. The Journal of Cell Biology. 121: 673-8. PMID 8387531 DOI: 10.1083/Jcb.121.3.673 |
0.399 |
|
| 1993 |
Meredith JE, Fazeli B, Schwartz MA. The extracellular matrix as a cell survival factor. Molecular Biology of the Cell. 4: 953-61. PMID 8257797 DOI: 10.1091/Mbc.4.9.953 |
0.381 |
|
| 1993 |
Leavesley DI, Schwartz MA, Rosenfeld M, Cheresh DA. Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms. Journal of Cell Biology. 121: 163-170. PMID 7681432 DOI: 10.1083/Jcb.121.1.163 |
0.318 |
|
| 1992 |
Schwartz MA, Van Wart HE. Synthetic inhibitors of bacterial and mammalian interstitial collagenases. Progress in Medicinal Chemistry. 29: 271-334. PMID 1475372 DOI: 10.1016/S0079-6468(08)70011-0 |
0.309 |
|
| 1992 |
Schwartz MA, Lechene C. Adhesion is required for protein kinase C-dependent activation of the Na+/H+ antiporter by platelet-derived growth factor Proceedings of the National Academy of Sciences of the United States of America. 89: 6138-6141. PMID 1378621 DOI: 10.1073/Pnas.89.13.6138 |
0.4 |
|
| 1992 |
Schwartz MA. Transmembrane signalling by integrins Trends in Cell Biology. 2: 304-308. DOI: 10.1016/0962-8924(92)90120-C |
0.355 |
|
| 1991 |
Schwartz MA, Ingber DE, Lawrence M, Springer TA, Lechene C. Multiple integrins share the ability to induce elevation of intracellular pH. Experimental Cell Research. 195: 533-5. PMID 1712734 DOI: 10.1016/0014-4827(91)90407-L |
0.363 |
|
| 1991 |
Schwartz MA, Lechene C, Ingber DE. Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape. Proceedings of the National Academy of Sciences of the United States of America. 88: 7849-53. PMID 1652767 DOI: 10.1073/Pnas.88.17.7849 |
0.369 |
|
| 1990 |
Ingber DE, Prusty D, Frangioni JV, Cragoe EJ, Lechene C, Schwartz MA. Control of intracellular pH and growth by fibronectin in capillary endothelial cells. The Journal of Cell Biology. 110: 1803-11. PMID 2159481 DOI: 10.1083/Jcb.110.5.1803 |
0.331 |
|
| 1989 |
Schwartz MA, Both G, Lechene C. Effect of cell spreading on cytoplasmic pH in normal and transformed fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 86: 4525-4529. PMID 2734302 DOI: 10.1073/Pnas.86.12.4525 |
0.316 |
|
| 1985 |
Sitkovsky MV, Schwartz MA, Eisen HN. Cell-cell contact proteins in antigen-specific and antigen-nonspecific cellular cytotoxicity. Advances in Experimental Medicine and Biology. 184: 429-49. PMID 3875975 DOI: 10.1007/978-1-4684-8326-0_29 |
0.308 |
|
| 1982 |
Lahav J, Schwartz MA, Hynes RO. Analysis of platelet adhesion with a radioactive chemical crosslinking reagent: interaction of thrombospondin with fibronectin and collagen. Cell. 31: 253-62. PMID 7159924 DOI: 10.1016/0092-8674(82)90425-1 |
0.482 |
|
| 1982 |
Schwartz MA, Das OP, Hynes RO. A new radioactive cross-linking reagent for studying the interactions of proteins. The Journal of Biological Chemistry. 257: 2343-9. PMID 7061425 |
0.4 |
|
| 1980 |
Schwartz M, Parce J, McConnell H. Additions and Corrections - Hydrogen Atom Exchange between Nitroxides and Hydroxylamines. Journal of the American Chemical Society. 102: 890-891. DOI: 10.1021/Ja00522A603 |
0.405 |
|
| 1979 |
Schwartz MA, Parce JW, McConnell HM. Hydrogen atom exchange between nitroxides and hydroxylamines Journal of the American Chemical Society. 101: 3592-3595. DOI: 10.1021/Ja00507A026 |
0.403 |
|
| 1979 |
Parce JW, Schwartz MA, Owicki JC, McConnell HM. Kinetics of antibody association with spin-label haptens on membrane surfaces The Journal of Physical Chemistry. 83: 3414-3417. DOI: 10.1021/J100489A019 |
0.423 |
|
| 1978 |
Schwartz MA, McConnell HM. Surface areas of lipid membranes. Biochemistry. 17: 837-40. PMID 629935 DOI: 10.1021/Bi00598A014 |
0.432 |
|
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