Robert Terkeltaub - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Molecular Biology, Pathology

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sanchez-Lopez E, Zhong Z, Stubelius A, Sweeney SR, Booshehri LM, Antonucci L, Liu-Bryan R, Lodi A, Terkeltaub R, Lacal JC, Murphy AN, Hoffman HM, Tiziani S, Guma M, Karin M. Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production. Cell Metabolism. PMID 30982734 DOI: 10.1016/J.Cmet.2019.03.011  0.308
2019 Serrano RL, Yu W, Graham RM, Bryan RL, Terkeltaub R. A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia. Plos One. 14: e0212235. PMID 30943188 DOI: 10.1371/Journal.Pone.0212235  0.318
2018 McWherter C, Choi YJ, Serrano RL, Mahata SK, Terkeltaub R, Liu-Bryan R. Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling. Arthritis Research & Therapy. 20: 204. PMID 30189890 DOI: 10.1186/S13075-018-1699-4  0.315
2018 Jin Y, Cong Q, Gvozdenovic-Jeremic J, Hu J, Zhang Y, Terkeltaub R, Yang Y. inhibits ectopic joint calcification and maintains articular chondrocytes by repressing Hedgehog signaling. Development (Cambridge, England). PMID 30111653 DOI: 10.1242/Dev.164830  0.332
2018 Serrano RL, Chen LY, Lotz MK, Liu-Bryan R, Terkeltaub R. Proteasomal function is impaired in human osteoarthritic chondrocytes and this can contribute to decreased SOX9 and aggrecan. Arthritis & Rheumatology (Hoboken, N.J.). PMID 29457374 DOI: 10.1002/Art.40456  0.302
2017 Terkeltaub R. What makes gouty inflammation so variable? Bmc Medicine. 15: 158. PMID 28818081 DOI: 10.1186/S12916-017-0922-5  0.303
2016 Merriman T, Terkeltaub R. PPARGC1B: insight into the expression of the gouty inflammation phenotype: PPARGC1B and gouty inflammation. Rheumatology (Oxford, England). PMID 28003496 DOI: 10.1093/Rheumatology/Kew453  0.301
2016 Wang Y, Viollet B, Terkeltaub R, Liu-Bryan R. AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages. Annals of the Rheumatic Diseases. 75: 286-94. PMID 25362043 DOI: 10.1136/Annrheumdis-2014-206074  0.33
2016 Terkeltaub R. SP0123 gout: A Variable Inflammatory Disease Annals of the Rheumatic Diseases. 75: 30-30. DOI: 10.1136/Annrheumdis-2016-Eular.3326  0.351
2015 Liu-Bryan R, Terkeltaub R. Emerging regulators of the inflammatory process in osteoarthritis. Nature Reviews. Rheumatology. 11: 35-44. PMID 25266449 DOI: 10.1038/Nrrheum.2014.162  0.338
2013 Petursson F, Husa M, June R, Lotz M, Terkeltaub R, Liu-Bryan R. Linked decreases in liver kinase B1 and AMP-activated protein kinase activity modulate matrix catabolic responses to biomechanical injury in chondrocytes. Arthritis Research & Therapy. 15: R77. PMID 23883619 DOI: 10.1186/Ar4254  0.328
2013 Zhao X, Terkeltaub R, Lotz M, Liu-Bryan R. AMPK-SIRT1-PGC-1α signaling regulates mitochondrial function in human articular chondrocytes Osteoarthritis and Cartilage. 21: S128. DOI: 10.1016/J.Joca.2013.02.269  0.332
2012 Dammanahalli KJ, Stevens S, Terkeltaub R. Vanin-1 pantetheinase drives smooth muscle cell activation in post-arterial injury neointimal hyperplasia. Plos One. 7: e39106. PMID 22720042 DOI: 10.1371/Journal.Pone.0039106  0.322
2012 Liu-Bryan R, Terkeltaub R. The growing array of innate inflammatory ignition switches in osteoarthritis. Arthritis and Rheumatism. 64: 2055-8. PMID 22488656 DOI: 10.1002/Art.34492  0.359
2011 Terkeltaub R, Yang B, Lotz M, Liu-Bryan R. Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α. Arthritis and Rheumatism. 63: 1928-37. PMID 21400477 DOI: 10.1002/Art.30333  0.308
2011 Cecil DL, Terkeltaub RA. Arterial calcification is driven by RAGE in Enpp1-/- mice. Journal of Vascular Research. 48: 227-35. PMID 21099228 DOI: 10.1159/000318805  0.699
2010 Polewski MD, Johnson KA, Foster M, Millán JL, Terkeltaub R. Inorganic pyrophosphatase induces type I collagen in osteoblasts. Bone. 46: 81-90. PMID 19733704 DOI: 10.1016/J.Bone.2009.08.055  0.32
2009 Cecil DL, Appleton CT, Polewski MD, Mort JS, Schmidt AM, Bendele A, Beier F, Terkeltaub R. The pattern recognition receptor CD36 is a chondrocyte hypertrophy marker associated with suppression of catabolic responses and promotion of repair responses to inflammatory stimuli. Journal of Immunology (Baltimore, Md. : 1950). 182: 5024-31. PMID 19342682 DOI: 10.4049/Jimmunol.0803603  0.738
2009 Bryan R, Husa M, Terkeltaub R. 228 CHONDROCYTE AMP-ACTIVATED PROTEIN KINASE (AMPK) ACTIVITY IS CHONDROPROTECTIVE BUT IS DECREASED BY INFLAMMATION AND IN OA CHONDROCYTES Osteoarthritis and Cartilage. 17: S128-S129. DOI: 10.1016/S1063-4584(09)60250-8  0.308
2008 Terkeltaub R. Macrophage glucocorticoid receptors join the intercellular dialogue in atherosclerotic lesion calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2096-8. PMID 19020314 DOI: 10.1161/Atvbaha.108.176461  0.306
2008 Cecil DL, Terkeltaub R. Transamidation by transglutaminase 2 transforms S100A11 calgranulin into a procatabolic cytokine for chondrocytes. Journal of Immunology (Baltimore, Md. : 1950). 180: 8378-85. PMID 18523305 DOI: 10.4049/Jimmunol.180.12.8378  0.739
2007 Cecil D, Appleton C, Beier F, Terkeltaub R. 39 EXPRESSION OF THE PATTERNING RECEPTOR CD36 IS CHONDROPROTECTIVE BY DISENGAGING INFLAMMATION FROM DYSREGULATED CHONDROCYTE DIFFERENTIATION AND FUNCTION Osteoarthritis and Cartilage. 15: C36-C37. DOI: 10.1016/S1063-4584(07)61675-6  0.708
2006 Terkeltaub R. Physiologic and pathologic functions of the NPP nucleotide pyrophosphatase/phosphodiesterase family focusing on NPP1 in calcification. Purinergic Signalling. 2: 371-7. PMID 18404477 DOI: 10.1007/S11302-005-5304-3  0.334
2006 Scott P, Ma H, Viriyakosol S, Terkeltaub R, Liu-Bryan R. Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals. Journal of Immunology (Baltimore, Md. : 1950). 177: 6370-8. PMID 17056568 DOI: 10.4049/Jimmunol.177.9.6370  0.326
2006 Rose DM, Sydlaske AD, Agha-Babakhani A, Johnson K, Terkeltaub R. Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils. Arthritis and Rheumatism. 54: 3363-71. PMID 17009310 DOI: 10.1002/Art.22137  0.316
2006 Cronstein BN, Terkeltaub R. The inflammatory process of gout and its treatment. Arthritis Research & Therapy. 8: S3. PMID 16820042 DOI: 10.1186/Ar1908  0.313
2005 Cecil DL, Johnson K, Rediske J, Lotz M, Schmidt AM, Terkeltaub R. Inflammation-induced chondrocyte hypertrophy is driven by receptor for advanced glycation end products. Journal of Immunology (Baltimore, Md. : 1950). 175: 8296-302. PMID 16339570 DOI: 10.4049/Jimmunol.175.12.8296  0.745
2005 Liu-Bryan R, Scott P, Sydlaske A, Rose DM, Terkeltaub R. Innate immunity conferred by Toll-like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal-induced inflammation. Arthritis and Rheumatism. 52: 2936-46. PMID 16142712 DOI: 10.1002/Art.21238  0.305
2005 Burton DW, Foster M, Johnson KA, Hiramoto M, Deftos LJ, Terkeltaub R. Chondrocyte calcium-sensing receptor expression is up-regulated in early guinea pig knee osteoarthritis and modulates PTHrP, MMP-13, and TIMP-3 expression. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 13: 395-404. PMID 15882563 DOI: 10.1016/J.Joca.2005.01.002  0.367
2005 Liu-Bryan R, Pritzker K, Firestein GS, Terkeltaub R. TLR2 signaling in chondrocytes drives calcium pyrophosphate dihydrate and monosodium urate crystal-induced nitric oxide generation. Journal of Immunology (Baltimore, Md. : 1950). 174: 5016-23. PMID 15814732 DOI: 10.4049/Jimmunol.174.8.5016  0.36
2005 Rutsch F, Terkeltaub R. Deficiencies of physiologic calcification inhibitors and low-grade inflammation in arterial calcification: lessons for cartilage calcification. Joint, Bone, Spine : Revue Du Rhumatisme. 72: 110-8. PMID 15797489 DOI: 10.1016/J.Jbspin.2004.05.014  0.313
2005 Cecil DL, Rose DM, Terkeltaub R, Liu-Bryan R. Role of interleukin-8 in PiT-1 expression and CXCR1-mediated inorganic phosphate uptake in chondrocytes. Arthritis and Rheumatism. 52: 144-54. PMID 15641067 DOI: 10.1002/Art.20748  0.737
2005 Johnson K, Polewski M, van Etten D, Terkeltaub R. Chondrogenesis mediated by PPi depletion promotes spontaneous aortic calcification in NPP1-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 686-91. PMID 15625282 DOI: 10.1161/01.Atv.0000154774.71187.F0  0.323
2005 Johnson K, Terkeltaub R. Inorganic pyrophosphate (PPI) in pathologic calcification of articular cartilage. Frontiers in Bioscience : a Journal and Virtual Library. 10: 988-97. PMID 15569637 DOI: 10.2741/1593  0.37
2004 Johnson K, Terkeltaub R. Upregulated ank expression in osteoarthritis can promote both chondrocyte MMP-13 expression and calcification via chondrocyte extracellular PPi excess. Osteoarthritis and Cartilage. 12: 321-35. PMID 15023384 DOI: 10.1016/J.Joca.2003.12.004  0.333
2004 Liu R, Lioté F, Rose DM, Merz D, Terkeltaub R. Proline-rich tyrosine kinase 2 and Src kinase signaling transduce monosodium urate crystal-induced nitric oxide production and matrix metalloproteinase 3 expression in chondrocytes. Arthritis and Rheumatism. 50: 247-58. PMID 14730623 DOI: 10.1002/Art.11486  0.308
2003 Merz D, Liu R, Johnson K, Terkeltaub R. IL-8/CXCL8 and growth-related oncogene alpha/CXCL1 induce chondrocyte hypertrophic differentiation. Journal of Immunology (Baltimore, Md. : 1950). 171: 4406-15. PMID 14530367 DOI: 10.4049/Jimmunol.171.8.4406  0.391
2003 Johnson K, Goding J, Van Etten D, Sali A, Hu SI, Farley D, Krug H, Hessle L, Millán JL, Terkeltaub R. Linked deficiencies in extracellular PP(i) and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 994-1004. PMID 12817751 DOI: 10.1359/Jbmr.2003.18.6.994  0.344
2003 Johnson K, Farley D, Hu SI, Terkeltaub R. One of two chondrocyte-expressed isoforms of cartilage intermediate-layer protein functions as an insulin-like growth factor 1 antagonist. Arthritis and Rheumatism. 48: 1302-14. PMID 12746903 DOI: 10.1002/Art.10927  0.323
2003 Pay S, Terkeltaub R. Calcium pyrophosphate dihydrate and hydroxyapatite crystal deposition in the joint: new developments relevant to the clinician. Current Rheumatology Reports. 5: 235-43. PMID 12744817 DOI: 10.1007/S11926-003-0073-X  0.314
2003 Rutsch F, Terkeltaub R. Parallels between arterial and cartilage calcification: what understanding artery calcification can teach us about chondrocalcinosis. Current Opinion in Rheumatology. 15: 302-10. PMID 12707585 DOI: 10.1097/00002281-200305000-00019  0.324
2002 Terkeltaub R, Johnson K, Murphy A, Ghosh S. Invited review: the mitochondrion in osteoarthritis. Mitochondrion. 1: 301-19. PMID 16120285 DOI: 10.1016/S1567-7249(01)00037-X  0.311
2001 Johnson K, Hashimoto S, Lotz M, Pritzker K, Terkeltaub R. Interleukin-1 induces pro-mineralizing activity of cartilage tissue transglutaminase and factor XIIIa. The American Journal of Pathology. 159: 149-63. PMID 11438463 DOI: 10.1016/S0002-9440(10)61682-3  0.364
2001 Johnson K, Hashimoto S, Lotz M, Pritzker K, Goding J, Terkeltaub R. Up-regulated expression of the phosphodiesterase nucleotide pyrophosphatase family member PC-1 is a marker and pathogenic factor for knee meniscal cartilage matrix calcification. Arthritis and Rheumatism. 44: 1071-81. PMID 11352238 DOI: 10.1002/1529-0131(200105)44:5<1071::Aid-Anr187>3.0.Co;2-3  0.339
2001 Liu R, Aupperle K, Terkeltaub R. Src family protein tyrosine kinase signaling mediates monosodium urate crystal-induced IL-8 expression by monocytic THP-1 cells. Journal of Leukocyte Biology. 70: 961-968. DOI: 10.1189/Jlb.70.6.961  0.318
2000 Johnson KA, Hessle L, Vaingankar S, Wennberg C, Mauro S, Narisawa S, Goding JW, Sano K, Millan JL, Terkeltaub R. Osteoblast tissue-nonspecific alkaline phosphatase antagonizes and regulates PC-1. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 279: R1365-77. PMID 11004006 DOI: 10.1152/Ajpregu.2000.279.4.R1365  0.303
2000 Liu R, O'Connell M, Johnson K, Pritzker K, Mackman N, Terkeltaub R. Extracellular signal-regulated kinase 1/extracellular signal-regulated kinase 2 mitogen-activated protein kinase signaling and activation of activator protein 1 and nuclear factor κB transcription factors play central roles in interleukin-8 expression stimulated by monosodium urate monohydrate and calcium pyrophosphate crystals in monocytic cells Arthritis & Rheumatism. 43: 1145-1155. PMID 10817569 DOI: 10.1002/1529-0131(200005)43:5<1145::Aid-Anr25>3.0.Co;2-T  0.336
1999 Terkeltaub R, Lotz M, Johnson K, Deng D, Hashimoto S, Goldring MB, Burton D, Deftos LJ. Parathyroid hormone-related proteins is abundant in osteoarthritic cartilage, and the parathyroid hormone-related protein 1-173 isoform is selectively induced by transforming growth factor beta in articular chondrocytes and suppresses generation of extracellular inorganic pyrophosphate. Arthritis and Rheumatism. 41: 2152-64. PMID 9870872 DOI: 10.1002/1529-0131(199812)41:12<2152::Aid-Art10>3.0.Co;2-X  0.335
1998 Terkeltaub R, Boisvert WA, Curtiss LK. Chemokines and atherosclerosis. Current Opinion in Lipidology. 9: 397-405. PMID 9812193 DOI: 10.1097/00041433-199810000-00003  0.314
1998 Terkeltaub R, Baird S, Sears P, Santiago R, Boisvert W. The murine homolog of the interleukin-8 receptor CXCR-2 is essential for the occurrence of neutrophilic inflammation in the air pouch model of acute urate crystal-induced gouty synovitis. Arthritis and Rheumatism. 41: 900-9. PMID 9588743 DOI: 10.1002/1529-0131(199805)41:5<900::Aid-Art18>3.0.Co;2-K  0.302
1998 Hashimoto S, Ochs RL, Rosen F, Quach J, McCabe G, Solan J, Seegmiller JE, Terkeltaub R, Lotz M. Chondrocyte-derived apoptotic bodies and calcification of articular cartilage. Proceedings of the National Academy of Sciences of the United States of America. 95: 3094-9. PMID 9501221 DOI: 10.1073/Pnas.95.6.3094  0.305
1994 Terkeltaub R, Solan J, Barry M, Santoro D, Bokoch GM. Role of the mevalonate pathway of isoprenoid synthesis in IL-8 generation by activated monocytic cells Journal of Leukocyte Biology. 55: 749-755. PMID 8195701 DOI: 10.1002/Jlb.55.6.749  0.314
1994 Huang R, Rosenbach M, Vaughn R, Provvedini D, Rebbe N, Hickman S, Goding J, Terkeltaub R. Expression of the murine plasma cell nucleotide pyrophosphohydrolase PC-1 is shared by human liver, bone, and cartilage cells. Regulation of PC-1 expression in osteosarcoma cells by transforming growth factor-beta. The Journal of Clinical Investigation. 94: 560-7. PMID 8040311 DOI: 10.1172/Jci117370  0.306
1992 Villiger PM, Terkeltaub R, Lotz M. Monocyte chemoattractant protein-1 (MCP-1) expression in human articular cartilage. Induction by peptide regulatory factors and differential effects of dexamethasone and retinoic acid. The Journal of Clinical Investigation. 90: 488-96. PMID 1365641 DOI: 10.1172/Jci115885  0.374
1991 Terkeltaub R, Zachariae C, Santoro D, Martin J, Peveri P, Matsushima K. Monocyte-derived neutrophil chemotactic factor/interleukin-8 is a potential mediator of crystal-induced inflammation. Arthritis and Rheumatism. 34: 894-903. PMID 2059236 DOI: 10.1002/Art.1780340716  0.315
1989 Guerne PA, Terkeltaub R, Zuraw B, Lotz M. Inflammatory microcrystals stimulate interleukin-6 production and secretion by human monocytes and synoviocytes. Arthritis and Rheumatism. 32: 1443-52. PMID 2554932 DOI: 10.1002/Anr.1780321114  0.308
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