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Vasilena Gocheva, Ph.D. - Publications

Affiliations: 
2011 Weill Cornell Medical College, New York, NY, United States 
Area:
Genetics, Cell Biology, Molecular Biology, Oncology
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Damo M, Fitzgerald B, Lu Y, Nader M, William I, Cheung JF, Connolly KA, Foster GG, Akama-Garren E, Lee DY, Chang GP, Gocheva V, Schmidt LM, Boileve A, Wilson JH, et al. Inducible de novo expression of neoantigens in tumor cells and mice. Nature Biotechnology. PMID 32719479 DOI: 10.1038/S41587-020-0613-1  0.399
2020 Lau AN, Li Z, Danai LV, Westermark AM, Darnell AM, Ferreira R, Gocheva V, Sivanand S, Lien EC, Sapp KM, Mayers JR, Biffi G, Chin CR, Davidson SM, Tuveson DA, et al. Dissecting cell type-specific metabolism in pancreatic ductal adenocarcinoma. Elife. 9. PMID 32648540 DOI: 10.7554/Elife.56782  0.51
2020 Lau AN, Li Z, Danai LV, Westermark AM, Darnell AM, Ferreira R, Gocheva V, Sivanand S, Lien EC, Sapp KM, Mayers JR, Biffi G, Chin CR, Davidson SM, Tuveson DA, et al. Author response: Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma Elife. DOI: 10.7554/Elife.56782.Sa2  0.301
2018 Dayton TL, Gocheva V, Miller KM, Bhutkar A, Lewis CA, Bronson RT, Vander Heiden MG, Jacks T. Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma. Cancer & Metabolism. 6: 6. PMID 29854399 DOI: 10.1186/S40170-018-0179-2  0.407
2017 Gocheva V, Naba A, Bhutkar A, Guardia T, Miller KM, Li CM, Dayton TL, Sanchez-Rivera FJ, Kim-Kiselak C, Jailkhani N, Winslow MM, Del Rosario A, Hynes RO, Jacks T. Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival. Proceedings of the National Academy of Sciences of the United States of America. PMID 28652369 DOI: 10.1073/Pnas.1707054114  0.457
2016 Muzumdar MD, Dorans KJ, Chung KM, Robbins R, Tammela T, Gocheva V, Li CM, Jacks T. Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers. Nature Communications. 7: 12685. PMID 27585860 DOI: 10.1038/Ncomms12685  0.362
2016 Edgington-Mitchell LE, Wartmann T, Fleming AK, Gocheva V, van der Linden WA, Withana NP, Verdoes M, Aurelio L, Edgington-Mitchell D, Lieu T, Parker BS, Graham B, Reinheckel T, Furness JB, Joyce JA, et al. Legumain is Activated in Macrophages during Pancreatitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00047.2016. PMID 27514475 DOI: 10.1152/Ajpgi.00047.2016  0.651
2016 Prudova A, Gocheva V, Auf dem Keller U, Eckhard U, Olson OC, Akkari L, Butler GS, Fortelny N, Lange PF, Mark JC, Joyce JA, Overall CM. TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors. Cell Reports. PMID 27477282 DOI: 10.1016/J.Celrep.2016.06.086  0.662
2016 Dayton TL, Gocheva V, Miller KM, Israelsen WJ, Bhutkar A, Clish CB, Davidson SM, Luengo A, Bronson RT, Jacks T, Vander Heiden MG. Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma. Genes & Development. PMID 27125672 DOI: 10.1101/Gad.278549.116  0.323
2016 Akkari L, Gocheva V, Quick ML, Kester JC, Spencer AK, Garfall AL, Bowman RL, Joyce JA. Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer. Genes & Development. 30: 220-32. PMID 26773004 DOI: 10.1101/Gad.270439.115  0.749
2016 Dayton TL, Gocheva V, Miller KM, Israelsen WJ, Clish CB, Bhutkar A, Davidson SM, Luengo A, Heiden MGV, Jacks TE. Abstract PR04: Germline loss of PK-M2 promotes metabolic syndrome and hepatocellular carcinoma Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-Pr04  0.329
2015 Dimitrova N, Gocheva V, Bhutkar A, Resnick R, Jong RM, Miller KM, Bendor J, Jacks T. Stromal expression of miR-143/145 promotes neoangiogenesis in lung cancer development. Cancer Discovery. PMID 26586766 DOI: 10.1158/2159-8290.Cd-15-0854  0.361
2015 Li CM, Gocheva V, Oudin MJ, Bhutkar A, Wang SY, Date SR, Ng SR, Whittaker CA, Bronson RT, Snyder EL, Gertler FB, Jacks T. Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis. Genes & Development. 29: 1850-62. PMID 26341558 DOI: 10.1101/Gad.267393.115  0.463
2015 Sobotič B, Vizovišek M, Vidmar R, Van Damme P, Gocheva V, Joyce JA, Gevaert K, Turk V, Turk B, Fonović M. Proteomic Identification of Cysteine Cathepsin Substrates Shed from the Surface of Cancer Cells. Molecular & Cellular Proteomics : McP. 14: 2213-28. PMID 26081835 DOI: 10.1074/Mcp.M114.044628  0.656
2014 Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA. Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix. Genes & Development. 28: 2134-50. PMID 25274726 DOI: 10.1101/Gad.249599.114  0.803
2013 Jacobson LS, Lima H, Goldberg MF, Gocheva V, Tsiperson V, Sutterwala FS, Joyce JA, Gapp BV, Blomen VA, Chandran K, Brummelkamp TR, Diaz-Griffero F, Brojatsch J. Cathepsin-mediated necrosis controls the adaptive immune response by Th2 (T helper type 2)-associated adjuvants. The Journal of Biological Chemistry. 288: 7481-91. PMID 23297415 DOI: 10.1074/Jbc.M112.400655  0.597
2012 Pyonteck SM, Gadea BB, Wang HW, Gocheva V, Hunter KE, Tang LH, Joyce JA. Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development. Oncogene. 31: 1459-67. PMID 21822305 DOI: 10.1038/onc.2011.337  0.714
2011 Wang H, Gocheva V, Joyce JA. Abstract 459: Activation of macrophages by IL-4 and other cytokines: priming for protumoral functions Cancer Research. 71: 459-459. DOI: 10.1158/1538-7445.Am2011-459  0.592
2010 Gocheva V, Chen X, Peters C, Reinheckel T, Joyce JA. Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer. Biological Chemistry. 391: 937-45. PMID 20731543 DOI: 10.1515/Bc.2010.080  0.746
2010 Elie BT, Gocheva V, Shree T, Dalrymple SA, Holsinger LJ, Joyce JA. Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model. Biochimie. 92: 1618-24. PMID 20447439 DOI: 10.1016/J.Biochi.2010.04.023  0.791
2010 Gocheva V, Wang HW, Gadea BB, Shree T, Hunter KE, Garfall AL, Berman T, Joyce JA. IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion. Genes & Development. 24: 241-55. PMID 20080943 DOI: 10.1101/Gad.1874010  0.775
2009 Kohrt DM, Crary JI, Gocheva V, Hinds PW, Grossel MJ. Distinct subcellular distribution of cyclin dependent kinase 6. Cell Cycle (Georgetown, Tex.). 8: 2837-43. PMID 19667758 DOI: 10.4161/Cc.8.17.9521  0.306
2009 Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF. VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Research. 69: 4537-44. PMID 19435903 DOI: 10.1158/0008-5472.Can-08-4539  0.632
2008 Reinheckel T, Gocheva V, Peters C, Joyce JA. Roles of cysteine proteases in tumor progression: Analysis of cysteine cathepsin knockout mice in cancer models The Cancer Degradome: Proteases and Cancer Biology. 281-304. DOI: 10.1007/978-0-387-69057-5_15  0.703
2007 Sadaghiani AM, Verhelst SH, Gocheva V, Hill K, Majerova E, Stinson S, Joyce JA, Bogyo M. Design, synthesis, and evaluation of in vivo potency and selectivity of epoxysuccinyl-based inhibitors of papain-family cysteine proteases. Chemistry & Biology. 14: 499-511. PMID 17524981 DOI: 10.1016/J.Chembiol.2007.03.010  0.586
2007 Gocheva V, Joyce JA. Cysteine cathepsins and the cutting edge of cancer invasion. Cell Cycle (Georgetown, Tex.). 6: 60-4. PMID 17245112 DOI: 10.4161/Cc.6.1.3669  0.743
2006 Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, Hanahan D, Joyce JA. Distinct roles for cysteine cathepsin genes in multistage tumorigenesis. Genes & Development. 20: 543-56. PMID 16481467 DOI: 10.1101/Gad.1407406  0.745
2006 Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, Hanahan D, Joyce J. ID: 356 Distinct roles for cysteine cathepsins in multistage tumorigenesis Journal of Thrombosis and Haemostasis. 4: 41-41. DOI: 10.1111/j.1538-7836.2006.00356.x  0.569
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