| Year |
Citation |
Score |
| 2022 |
Finlay DB, Nguyen T, Gamage TF, Chen S, Barrus DG, Patel PR, Thomas BF, Wiley JL, Zhang Y, Glass M. Exploring determinants of agonist efficacy at the CB1 cannabinoid receptor: Analogues of the synthetic cannabinoid receptor agonist EG-018. Pharmacology Research & Perspectives. 10: e00901. PMID 35041297 DOI: 10.1002/prp2.901 |
0.799 |
|
| 2021 |
Howlett AC, Thomas BF, Huffman JW. The Spicy Story of Cannabimimetic Indoles. Molecules (Basel, Switzerland). 26. PMID 34684770 DOI: 10.3390/molecules26206190 |
0.409 |
|
| 2020 |
Gamage TF, Barrus DG, Kevin RC, Finlay DB, Lefever TW, Patel PR, Grabenauer MA, Glass M, McGregor IS, Wiley JL, Thomas BF. In vitro and in vivo pharmacological evaluation of the synthetic cannabinoid receptor agonist EG-018. Pharmacology, Biochemistry, and Behavior. 172918. PMID 32247816 DOI: 10.1016/J.Pbb.2020.172918 |
0.813 |
|
| 2019 |
Nguyen T, Gamage T, Decker AM, Barrus D, Langston TL, Li JX, Thomas BF, Zhang Y. Synthesis and Pharmacological Evaluation of 1-Phenyl-3-Thiophenylurea Derivatives as Cannabinoid Type-1 Receptor Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31596583 DOI: 10.1021/Acs.Jmedchem.9B01161 |
0.765 |
|
| 2019 |
Lefever TW, Thomas BF, Kovach AL, Snyder RW, Wiley JL. Route of administration effects on nicotine discrimination in female and male mice. Drug and Alcohol Dependence. 204: 107504. PMID 31476643 DOI: 10.1016/J.Drugalcdep.2019.06.007 |
0.552 |
|
| 2019 |
Nguyen T, Thomas BF, Zhang Y. Overcoming the psychiatric side effects of the cannabinoid CB1 receptor antagonists: Current approaches for therapeutics development. Current Topics in Medicinal Chemistry. PMID 31284863 DOI: 10.2174/1568026619666190708164841 |
0.436 |
|
| 2019 |
Marusich JA, Wiley JL, Silinski MAR, Thomas BF, Meredith SE, Gahl RF, Jackson KJ. Comparison of Cigarette, Little Cigar, and Waterpipe Tobacco Smoke Condensate and E-Cigarette Aerosol Condensate in a Self-administration Model. Behavioural Brain Research. 112061. PMID 31254537 DOI: 10.1016/J.Bbr.2019.112061 |
0.538 |
|
| 2019 |
Wiley JL, Lefever TW, Michelle Glass MA, Thomas BF. Do You Feel It Now? Route of Administration and Δ-Tetrahydrocannabinol-Like Discriminative Stimulus Effects of Synthetic Cannabinoids in Mice. Neurotoxicology. PMID 30953678 DOI: 10.1016/J.Neuro.2019.04.002 |
0.625 |
|
| 2019 |
Kevin RC, Kovach AL, Lefever TW, Gamage TF, Wiley JL, McGregor IS, Thomas BF. Toxic by design? Formation of thermal degradants and cyanide from carboxamide-type synthetic cannabinoids CUMYL-PICA, 5F-CUMYL-PICA, AMB-FUBINACA, MDMB-FUBINACA, NNEI, and MN-18 during exposure to high temperatures. Forensic Toxicology. 37: 17-26. PMID 30705707 DOI: 10.1007/S11419-018-0430-0 |
0.745 |
|
| 2018 |
Gamage TF, Farquhar CE, McKinnie RJ, Kevin RC, McGregor IS, Trudell M, Wiley JL, Thomas BF. Synthetic cannabinoid hydroxypentyl metabolites retain efficacy at human cannabinoid receptors. The Journal of Pharmacology and Experimental Therapeutics. PMID 30552295 DOI: 10.1124/Jpet.118.254425 |
0.806 |
|
| 2018 |
Farquhar CE, Breivogel CS, Gamage TF, Gay EA, Thomas BF, Craft RM, Wiley JL. Sex, THC, and hormones: Effects on density and sensitivity of CB cannabinoid receptors in rats. Drug and Alcohol Dependence. 194: 20-27. PMID 30391834 DOI: 10.1016/J.Drugalcdep.2018.09.018 |
0.763 |
|
| 2018 |
Nguyen T, Gamage TF, Decker AM, German N, Langston TL, Farquhar CE, Kenakin TP, Wiley JL, Thomas BF, Zhang Y. Diarylureas Containing 5-Membered Heterocycles as CB1 Receptor Allosteric Modulators: Design, Synthesis, and Pharmacological Evaluation. Acs Chemical Neuroscience. PMID 30188693 DOI: 10.1021/Acschemneuro.8B00396 |
0.798 |
|
| 2018 |
Gamage TF, Farquhar CE, Lefever TW, Marusich JA, Kevin RC, McGregor IS, Wiley JL, Thomas BF. Molecular and behavioral pharmacological characterization of abused synthetic cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-fluoro-CUMYL-PICA. The Journal of Pharmacology and Experimental Therapeutics. PMID 29549157 DOI: 10.1124/Jpet.117.246983 |
0.812 |
|
| 2017 |
Marusich JA, Wiley JL, Lefever TW, Patel PR, Thomas BF. Finding order in chemical chaos - Continuing characterization of synthetic cannabinoid receptor agonists. Neuropharmacology. PMID 29113898 DOI: 10.1016/J.Neuropharm.2017.10.041 |
0.687 |
|
| 2017 |
Kevin RC, Lefever TW, Snyder RW, Patel PR, Gamage TF, Fennell TR, Wiley JL, McGregor IS, Thomas BF. Kinetic and metabolic profiles of synthetic cannabinoids NNEI and MN-18. Drug Testing and Analysis. PMID 28834241 DOI: 10.1002/Dta.2262 |
0.754 |
|
| 2017 |
Kevin RC, Lefever TW, Snyder RW, Patel PR, Fennell TR, Wiley JL, McGregor IS, Thomas BF. In vitro and in vivo pharmacokinetics and metabolism of synthetic cannabinoids CUMYL-PICA and 5F-CUMYL-PICA. Forensic Toxicology. 35: 333-347. PMID 28824730 DOI: 10.1007/S11419-017-0361-1 |
0.58 |
|
| 2017 |
Gamage TF, Farquhar CE, Lefever TW, Thomas BF, Nguyen T, Zhang Y, Wiley JL. The great divide: Separation between in vitro and in vivo effects of PSNCBAM-based CB1 receptor allosteric modulators. Neuropharmacology. PMID 28803965 DOI: 10.1016/J.Neuropharm.2017.08.008 |
0.804 |
|
| 2017 |
Nguyen T, German N, Decker AM, Langston TL, Gamage TF, Farquhar CE, Li JX, Wiley JL, Thomas BF, Zhang Y. Novel Diarylurea Based Allosteric Modulators of the Cannabinoid CB1 Receptor: Evaluation of Importance of 6-Pyrrolidinylpyridinyl Substitution. Journal of Medicinal Chemistry. PMID 28792219 DOI: 10.1021/Acs.Jmedchem.7B00707 |
0.806 |
|
| 2017 |
Thomas BF. Interactions of Cannabinoids With Biochemical Substrates. Substance Abuse : Research and Treatment. 11: 1178221817711418. PMID 28607542 DOI: 10.1177/1178221817711418 |
0.444 |
|
| 2017 |
Lefever TW, Marusich JA, Thomas BF, Barrus DG, Peiper NC, Kevin RC, Wiley JL. Vaping Synthetic Cannabinoids: A Novel Preclinical Model of E-Cigarette Use in Mice. Substance Abuse : Research and Treatment. 11: 1178221817701739. PMID 28469427 DOI: 10.1177/1178221817701739 |
0.592 |
|
| 2017 |
Grim TW, Morales AJ, Thomas BF, Wiley JL, Endres GW, Negus SS, Lichtman AH. Apparent CB1 receptor rimonabant affinity estimates: combination with THC and synthetic cannabinoids in the mouse in vivo triad model. The Journal of Pharmacology and Experimental Therapeutics. PMID 28442584 DOI: 10.1124/Jpet.117.240192 |
0.739 |
|
| 2017 |
Lefever TW, Lee YO, Kovach AL, Silinski MA, Marusich JA, Thomas BF, Wiley JL. Delivery of nicotine aerosol to mice via a modified electronic cigarette device. Drug and Alcohol Dependence. 172: 80-87. PMID 28157590 DOI: 10.1016/J.Drugalcdep.2016.12.004 |
0.541 |
|
| 2017 |
Thomas BF, Lefever TW, Cortes RA, Kovach AL, Cox AO, Patel PR, Pollard GT, Marusich JA, Kevin RA, Gamage TF, Wiley JL. Thermolytic degradation of synthetic cannabinoids: chemical exposures and pharmacological consequences. The Journal of Pharmacology and Experimental Therapeutics. PMID 28087785 DOI: 10.1124/Jpet.116.238717 |
0.801 |
|
| 2017 |
Marusich JA, Lefever T, Blough B, Thomas B, Wiley J. Pharmacological effects of injected or vaporized methamphetamine and alpha-PVP in mice Drug and Alcohol Dependence. 171: e130. DOI: 10.1016/J.Drugalcdep.2016.08.361 |
0.508 |
|
| 2016 |
Nguyen T, Li JX, Thomas BF, Wiley JL, Kenakin TP, Zhang Y. Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor. Medicinal Research Reviews. PMID 27879006 DOI: 10.1002/Med.21418 |
0.666 |
|
| 2016 |
Wiley JL, Marusich JA, Thomas BF. Combination Chemistry: Structure-Activity Relationships of Novel Psychoactive Cannabinoids. Current Topics in Behavioral Neurosciences. PMID 27753007 DOI: 10.1007/7854_2016_17 |
0.674 |
|
| 2016 |
Grim TW, Morales AJ, Gonek MM, Wiley JL, Thomas BF, Endres GW, Sim-Selley LJ, Selley DE, Negus SS, Lichtman AH. Stratification of cannabinoid 1 receptor (CB1R) agonist efficacy: Manipulation of CB1R density through use of transgenic mice reveals congruence between in vivo and in vitro assays. The Journal of Pharmacology and Experimental Therapeutics. PMID 27535976 DOI: 10.1124/Jpet.116.233163 |
0.706 |
|
| 2016 |
Seltzman HH, Shiner C, Hirt EE, Gilliam AF, Thomas BF, Maitra R, Snyder R, Black SL, Patel PR, Mulpuri Y, Spigelman I. Peripherally selective cannabinoid 1 receptor (CB1R) agonists for the treatment of neuropathic pain. Journal of Medicinal Chemistry. PMID 27482723 DOI: 10.1021/Acs.Jmedchem.6B00516 |
0.375 |
|
| 2016 |
Wiley JL, Lefever TW, Marusich JA, Grabenauer M, Moore KN, Huffman JW, Thomas BF. Evaluation of first generation synthetic cannabinoids on binding at non-cannabinoid receptors and in a battery of in vivo assays in mice. Neuropharmacology. PMID 27449567 DOI: 10.1016/J.Neuropharm.2016.07.016 |
0.705 |
|
| 2016 |
Marusich JA, Lefever TW, Blough BE, Thomas BF, Wiley JL. Pharmacological Effects of Methamphetamine and Alpha-PVP Vapor and Injection. Neurotoxicology. PMID 27237056 DOI: 10.1016/J.Neuro.2016.05.015 |
0.585 |
|
| 2015 |
Perrey DA, Decker AM, Li JX, Gilmour BP, Thomas BF, Harris DL, Runyon SP, Zhang Y. The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor. Bioorganic & Medicinal Chemistry. PMID 26216017 DOI: 10.1016/J.Bmc.2015.07.013 |
0.505 |
|
| 2015 |
Wiley JL, Marusich JA, Lefever TW, Antonazzo KR, Wallgren MT, Cortes RA, Patel PR, Grabenauer M, Moore KN, Thomas BF. AB-CHMINACA, AB-PINACA, and FUBIMINA: Affinity and Potency of Novel Synthetic Cannabinoids in Producing Δ9-Tetrahydrocannabinol-Like Effects in Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 26105953 DOI: 10.1124/Jpet.115.225326 |
0.698 |
|
| 2015 |
Nguyen T, German N, Decker AM, Li JX, Wiley JL, Thomas BF, Kenakin TP, Zhang Y. Structure-activity relationships of substituted 1H-indole-2-carboxamides as CB1 receptor allosteric modulators. Bioorganic & Medicinal Chemistry. 23: 2195-203. PMID 25797163 DOI: 10.1016/J.Bmc.2015.02.058 |
0.651 |
|
| 2015 |
Perrey DA, German NA, Decker AM, Thorn D, Li JX, Gilmour BP, Thomas BF, Harris DL, Runyon SP, Zhang Y. Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptor. Acs Chemical Neuroscience. 6: 599-614. PMID 25643283 DOI: 10.1016/J.Drugalcdep.2015.07.659 |
0.503 |
|
| 2015 |
Schaich CL, Shaltout HA, Grabenauer M, Thomas BF, Gallagher PE, Howlett AC, Diz DI. Alterations in the Medullary Endocannabinoid System Contribute to Age-related Impairment of Baroreflex Sensitivity. Journal of Cardiovascular Pharmacology. 65: 473-9. PMID 25636077 DOI: 10.1097/Fjc.0000000000000216 |
0.321 |
|
| 2015 |
Wiley JL, Marusich JA, Thomas BF, Jackson KJ. Determination of behaviorally effective tobacco constituent doses in rats. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 17: 368-71. PMID 25271188 DOI: 10.1093/Ntr/Ntu194 |
0.566 |
|
| 2015 |
Zhang Y, Perrey DA, Harris DL, German NA, Decker AM, Gilmour BP, Thomas BF. Structure-activity relationship studies on the tetrahydroisoquinoline-based orexin 1 receptor antagonists: The 1-benzyl position Drug and Alcohol Dependence. 146. DOI: 10.1016/J.Drugalcdep.2014.09.765 |
0.435 |
|
| 2014 |
German N, Decker AM, Gilmour BP, Gay EA, Wiley JL, Thomas BF, Zhang Y. Diarylureas as allosteric modulators of the cannabinoid CB1 receptor: structure-activity relationship studies on 1-(4-chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1). Journal of Medicinal Chemistry. 57: 7758-69. PMID 25162172 DOI: 10.1021/Jm501042U |
0.683 |
|
| 2014 |
Perrey DA, Gilmour BP, Thomas BF, Zhang Y. Toward the Development of Bivalent Ligand Probes of Cannabinoid CB1 and Orexin OX1 Receptor Heterodimers. Acs Medicinal Chemistry Letters. 5: 634-8. PMID 24944734 DOI: 10.1021/Ml4004759 |
0.484 |
|
| 2014 |
Watterson LR, Kufahl PR, Nemirovsky NE, Sewalia K, Grabenauer M, Thomas BF, Marusich JA, Wegner S, Olive MF. Potent rewarding and reinforcing effects of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV). Addiction Biology. 19: 165-74. PMID 22784198 DOI: 10.1111/J.1369-1600.2012.00474.X |
0.3 |
|
| 2014 |
Zhang Y, Perrey D, German N, Gilmour B, Li J, Thomas B. Development of selective orexin-1 receptor antagonists Drug and Alcohol Dependence. 140: e249-e250. DOI: 10.1016/J.Drugalcdep.2014.02.690 |
0.419 |
|
| 2014 |
Daw R, Grabenauer M, Pande PG, Cox A, Kovach A, Davis K, Wiley J, Stout P, Thomas B. Pyrolysis studies of synthetic cannabinoids in herbal products Drug and Alcohol Dependence. 140: e44. DOI: 10.1016/J.Drugalcdep.2014.02.142 |
0.513 |
|
| 2013 |
German NA, Decker AM, Gilmour BP, Thomas BF, Zhang Y. Truncated Orexin Peptides: Structure-Activity Relationship Studies. Acs Medicinal Chemistry Letters. 4: 1224-1227. PMID 24707347 DOI: 10.1021/Ml400333A |
0.336 |
|
| 2013 |
Perrey DA, German NA, Gilmour BP, Li JX, Harris DL, Thomas BF, Zhang Y. Substituted tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor. Journal of Medicinal Chemistry. 56: 6901-16. PMID 23941044 DOI: 10.1021/Jm400720H |
0.473 |
|
| 2013 |
Wiley JL, Marusich JA, Lefever TW, Grabenauer M, Moore KN, Thomas BF. Cannabinoids in disguise: Δ9-tetrahydrocannabinol-like effects of tetramethylcyclopropyl ketone indoles. Neuropharmacology. 75: 145-54. PMID 23916483 DOI: 10.1016/J.Neuropharm.2013.07.022 |
0.686 |
|
| 2013 |
Kotsikorou E, Navas F, Roche MJ, Gilliam AF, Thomas BF, Seltzman HH, Kumar P, Song ZH, Hurst DP, Lynch DL, Reggio PH. The importance of hydrogen bonding and aromatic stacking to the affinity and efficacy of cannabinoid receptor CB2 antagonist, 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide (SR144528). Journal of Medicinal Chemistry. 56: 6593-612. PMID 23855811 DOI: 10.1021/Jm400070U |
0.426 |
|
| 2013 |
Hatsukami DK, Heishman SJ, Vogel RI, Denlinger RL, Roper-Batker AN, Mackowick KM, Jensen J, Murphy SE, Thomas BF, Donny E. Dose-response effects of spectrum research cigarettes. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 15: 1113-21. PMID 23178320 DOI: 10.1093/Ntr/Nts247 |
0.316 |
|
| 2013 |
Thomas BF, Pollard GT, Grabenauer M. Analytical surveillance of emerging drugs of abuse and drug formulations. Life Sciences. 92: 512-9. PMID 23154240 DOI: 10.1016/J.Lfs.2012.10.031 |
0.322 |
|
| 2012 |
Wiley JL, Marusich JA, Zhang Y, Fulp A, Maitra R, Thomas BF, Mahadevan A. Structural analogs of pyrazole and sulfonamide cannabinoids: effects on acute food intake in mice. European Journal of Pharmacology. 695: 62-70. PMID 22975289 DOI: 10.1016/J.Ejphar.2012.08.019 |
0.649 |
|
| 2012 |
Grabenauer M, Krol WL, Wiley JL, Thomas BF. Analysis of synthetic cannabinoids using high-resolution mass spectrometry and mass defect filtering: implications for nontargeted screening of designer drugs. Analytical Chemistry. 84: 5574-81. PMID 22724537 DOI: 10.1021/Ac300509H |
0.511 |
|
| 2012 |
Cox AO, Daw RC, Mason MD, Grabenauer M, Pande PG, Davis KH, Wiley JL, Stout PR, Thomas BF, Huffman JW. Use of SPME-HS-GC-MS for the analysis of herbal products containing synthetic cannabinoids. Journal of Analytical Toxicology. 36: 293-302. PMID 22582264 DOI: 10.1093/Jat/Bks025 |
0.597 |
|
| 2011 |
Wiley JL, Marusich JA, Huffman JW, Balster RL, Thomas BF. Hijacking of Basic Research: The Case of Synthetic Cannabinoids. Methods Report (Rti Press). 2011. PMID 23397508 DOI: 10.3768/rtipress.2011.op.0007.1111 |
0.488 |
|
| 2011 |
Perrey DA, Gilmour BP, Runyon SP, Thomas BF, Zhang Y. Diaryl urea analogues of SB-334867 as orexin-1 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 21: 2980-5. PMID 21478014 DOI: 10.1016/J.Bmcl.2011.03.048 |
0.492 |
|
| 2010 |
Zhang Y, Gilliam A, Maitra R, Damaj MI, Tajuba JM, Seltzman HH, Thomas BF. Synthesis and biological evaluation of bivalent ligands for the cannabinoid 1 receptor. Journal of Medicinal Chemistry. 53: 7048-60. PMID 20845959 DOI: 10.1021/Jm1006676 |
0.488 |
|
| 2010 |
Walentiny DM, Vann RE, Warner JA, King LS, Seltzman HH, Navarro HA, Twine CE, Thomas BF, Gilliam AF, Gilmour BP, Carroll FI, Wiley JL. Kappa opioid mediation of cannabinoid effects of the potent hallucinogen, salvinorin A, in rodents. Psychopharmacology. 210: 275-84. PMID 20354680 DOI: 10.1007/S00213-010-1827-6 |
0.668 |
|
| 2010 |
Thomas BF, Beardsley PM, Seltzman HH. Current considerations for development of cannabinoid receptor 1 antagonists (Drug Development Research (2009) 70, 8 (525-526) DOI: 10.1002/ddr.20332) Drug Development Research. 71: 159. DOI: 10.1002/Ddr.20361 |
0.4 |
|
| 2009 |
Beardsley PM, Thomas BF, McMahon LR. Cannabinoid CB1 receptor antagonists as potential pharmacotherapies for drug abuse disorders. International Review of Psychiatry (Abingdon, England). 21: 134-42. PMID 19367507 DOI: 10.1080/09540260902782786 |
0.311 |
|
| 2009 |
Thomas BF. Neuroanatomical basis for therapeutic applications of cannabinoid receptor 1 antagonists Drug Development Research. 70: 527-554. DOI: 10.1002/Ddr.20333 |
0.438 |
|
| 2009 |
Thomas BF. Cannabinoid CB1 receptor antagonists Drug Development Research. 70: 525-526. DOI: 10.1002/Ddr.20332 |
0.46 |
|
| 2008 |
Zhang Y, Burgess JP, Brackeen M, Gilliam A, Mascarella SW, Page K, Seltzman HH, Thomas BF. Conformationally constrained analogues of N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4- dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716): design, synthesis, computational analysis, and biological evaluations. Journal of Medicinal Chemistry. 51: 3526-39. PMID 18512901 DOI: 10.1021/Jm8000778 |
0.451 |
|
| 2007 |
Bourne C, Roy S, Wiley JL, Martin BR, Thomas BF, Mahadevan A, Razdan RK. Novel, potent THC/anandamide (hybrid) analogs. Bioorganic & Medicinal Chemistry. 15: 7850-64. PMID 17827022 DOI: 10.1016/J.Bmc.2007.08.039 |
0.605 |
|
| 2006 |
Thomas BF, Zhang Y, Brackeen M, Page KM, Mascarella SW, Seltzman HH. Conformational characteristics of the interaction of SR141716A with the CB1 cannabinoid receptor as determined through the use of conformationally constrained analogs. The Aaps Journal. 8: E665-71. PMID 17233530 DOI: 10.1208/Aapsj080476 |
0.496 |
|
| 2006 |
Paine MF, Widmer WW, Hart HL, Pusek SN, Beavers KL, Criss AB, Brown SS, Thomas BF, Watkins PB. A furanocoumarin-free grapefruit juice establishes furanocoumarins as the mediators of the grapefruit juice-felodipine interaction. The American Journal of Clinical Nutrition. 83: 1097-105. PMID 16685052 DOI: 10.1093/Ajcn/83.5.1097 |
0.306 |
|
| 2005 |
Beardsley PM, Thomas BF. Current evidence supporting a role of cannabinoid CB1 receptor (CB1R) antagonists as potential pharmacotherapies for drug abuse disorders. Behavioural Pharmacology. 16: 275-96. PMID 16148435 DOI: 10.1097/00008877-200509000-00003 |
0.314 |
|
| 2005 |
Thomas BF, Francisco ME, Seltzman HH, Thomas JB, Fix SE, Schulz AK, Gilliam AF, Pertwee RG, Stevenson LA. Synthesis of long-chain amide analogs of the cannabinoid CB1 receptor antagonist N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716) with unique binding selectivities and pharmacological activities. Bioorganic & Medicinal Chemistry. 13: 5463-74. PMID 15994087 DOI: 10.1016/J.Bmc.2005.06.005 |
0.455 |
|
| 2005 |
Varvel SA, Bridgen DT, Tao Q, Thomas BF, Martin BR, Lichtman AH. Delta9-tetrahydrocannbinol accounts for the antinociceptive, hypothermic, and cataleptic effects of marijuana in mice. The Journal of Pharmacology and Experimental Therapeutics. 314: 329-37. PMID 15831444 DOI: 10.1124/Jpet.104.080739 |
0.59 |
|
| 2003 |
Hunt PA, Koehler KE, Susiarjo M, Hodges CA, Ilagan A, Voigt RC, Thomas S, Thomas BF, Hassold TJ. Bisphenol a exposure causes meiotic aneuploidy in the female mouse. Current Biology : Cb. 13: 546-53. PMID 12676084 DOI: 10.1016/S0960-9822(03)00189-1 |
0.311 |
|
| 2003 |
Huffman JW, Miller JR, Liddle J, Yu S, Thomas BF, Wiley JL, Martin BR. Structure-activity relationships for 1',1'-dimethylalkyl-Delta8-tetrahydrocannabinols. Bioorganic & Medicinal Chemistry. 11: 1397-410. PMID 12628666 DOI: 10.1016/S0968-0896(02)00649-1 |
0.642 |
|
| 2003 |
Francisco MEY, Burgess JP, George C, Bailey GS, Gilliam AF, Seltzman HH, Thomas BF. Structure elucidation of a novel ring-constrained biaryl pyrazole CB 1 cannabinoid receptor antagonist Magnetic Resonance in Chemistry. 41: 265-268. DOI: 10.1002/Mrc.1174 |
0.403 |
|
| 2002 |
Francisco ME, Seltzman HH, Gilliam AF, Mitchell RA, Rider SL, Pertwee RG, Stevenson LA, Thomas BF. Synthesis and structure-activity relationships of amide and hydrazide analogues of the cannabinoid CB(1) receptor antagonist N-(piperidinyl)- 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716). Journal of Medicinal Chemistry. 45: 2708-19. PMID 12061874 DOI: 10.1021/Jm010498V |
0.468 |
|
| 2002 |
Martin BR, Jefferson RG, Winckler R, Wiley JL, Thomas BF, Crocker PJ, Williams W, Razdan RK. Assessment of structural commonality between tetrahydrocannabinol and anandamide. European Journal of Pharmacology. 435: 35-42. PMID 11790376 DOI: 10.1016/S0014-2999(01)01527-8 |
0.61 |
|
| 2001 |
Thomas BF, Zeisel SH, Busby MG, Hill JM, Mitchell RA, Scheffler NM, Brown SS, Bloeden LT, Dix KJ, Jeffcoat AR. Quantitative analysis of the principle soy isoflavones genistein, daidzein and glycitein, and their primary conjugated metabolites in human plasma and urine using reversed-phase high-performance liquid chromatography with ultraviolet detection. Journal of Chromatography. B, Biomedical Sciences and Applications. 760: 191-205. PMID 11530977 DOI: 10.1016/S0378-4347(01)00269-9 |
0.313 |
|
| 2001 |
Dix KJ, Coleman DP, Fossett JE, Gaudette NF, Stanley AP, Thomas BF, Jeffcoat AR. Disposition of propargyl alcohol in rat and mouse after intravenous, oral, dermal and inhalation exposure. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 31: 357-75. PMID 11513248 DOI: 10.1080/00498250110053228 |
0.305 |
|
| 1998 |
Reggio PH, Basu-Dutt S, Barnett-Norris J, Castro MT, Hurst DP, Seltzman HH, Roche MJ, Gilliam AF, Thomas BF, Stevenson LA, Pertwee RG, Abood ME. The bioactive conformation of aminoalkylindoles at the cannabinoid CB1 and CB2 receptors: insights gained from (E)- and (Z)-naphthylidene indenes. Journal of Medicinal Chemistry. 41: 5177-87. PMID 9857088 DOI: 10.1021/Jm9801197 |
0.609 |
|
| 1998 |
Thomas BF, Gilliam AF, Burch DF, Roche MJ, Seltzman HH. Comparative receptor binding analyses of cannabinoid agonists and antagonists. The Journal of Pharmacology and Experimental Therapeutics. 285: 285-92. PMID 9536023 |
0.367 |
|
| 1997 |
Seltzman HH, Fleming DN, Thomas BF, Gilliam AF, McCallion DS, Pertwee RG, Compton DR, Martin BR. Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide. Journal of Medicinal Chemistry. 40: 3626-34. PMID 9357529 DOI: 10.1021/Jm9702950 |
0.432 |
|
| 1997 |
Dutta AK, Ryan W, Thomas BF, Singer M, Compton DR, Martin BR, Razdan RK. Synthesis, pharmacology, and molecular modeling of novel 4-alkyloxy indole derivatives related to cannabimimetic aminoalkyl indoles (AAIs). Bioorganic & Medicinal Chemistry. 5: 1591-600. PMID 9313864 DOI: 10.1016/S0968-0896(97)00111-9 |
0.467 |
|
| 1996 |
Lever JR, Scheffel U, Stathis M, Seltzman HH, Wyrick CD, Abraham P, Parham K, Thomas BF, Boja JW, Kuhar MJ, Carroll FI. Synthesis and in vivo studies of a selective ligand for the dopamine transporter: 3 beta-(4-[125I]iodophenyl) tropan-2 beta-carboxylic acid isopropyl ester ([125I]RTI-121). Nuclear Medicine and Biology. 23: 277-84. PMID 8782237 DOI: 10.1016/0969-8051(95)02074-8 |
0.3 |
|
| 1995 |
Adams IB, Ryan W, Singer M, Thomas BF, Compton DR, Razdan RK, Martin BR. Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs. The Journal of Pharmacology and Experimental Therapeutics. 273: 1172-81. PMID 7791088 |
0.436 |
|
| 1993 |
Thomas BF, Martin BR. Further characterization of the cannabinoid receptor with 3H-11-OH-Δ9- THC-DMH binding in rat brain slices: Autoradiography, displacement studies and correlation to in vivo pharmacological potencies Nida Research Monograph Series. 375. |
0.312 |
|
| 1991 |
Thomas BF, Compton DR, Martin BR, Semus SF. Modeling the cannabinoid receptor: a three-dimensional quantitative structure-activity analysis. Molecular Pharmacology. 40: 656-65. PMID 1944237 |
0.334 |
|
| 1991 |
Martin BR, Compton DR, Thomas BF, Prescott WR, Little PJ, Razdan RK, Johnson MR, Melvin LS, Mechoulam R, Ward SJ. Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs. Pharmacology, Biochemistry, and Behavior. 40: 471-8. PMID 1666911 DOI: 10.1016/0091-3057(91)90349-7 |
0.399 |
|
| 1986 |
Lue LP, Scimeca JA, Thomas BF, Martin BR. Identification and quantification of phencyclidine pyrolysis products formed during smoking. Journal of Analytical Toxicology. 10: 81-6. PMID 3724075 DOI: 10.1093/Jat/10.3.81 |
0.307 |
|
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