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Sean G. Forrester, Ph.D. - Publications

Affiliations: 
2003 McGill University, Montreal, QC, Canada 
Area:
Molecular Biology
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24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Habibi S, Nazareth K, Nichols J, Varley S, Forrester SG. The Haemonchus contortus LGC-39 subunit is a novel subtype of an acetylcholine-gated chloride channel. International Journal For Parasitology. Drugs and Drug Resistance. 22: 20-26. PMID 37054482 DOI: 10.1016/j.ijpddr.2023.04.001  0.534
2022 Cochrane E, Foster J, Khatami MH, de Haan HW, Forrester SG. Characterization of adjacent charged residues near the agonist binding site of the nematode UNC-49 GABA receptor. Molecular and Biochemical Parasitology. 111521. PMID 36100173 DOI: 10.1016/j.molbiopara.2022.111521  0.4
2020 Habibi SA, Blazie SM, Jin Y, Forrester SG. Isolation and characterization of a novel member of the ACC ligand-gated chloride channel family, Hco-LCG-46, from the parasitic nematode Haemonchus contortus. Molecular and Biochemical Parasitology. 111276. PMID 32268182 DOI: 10.1016/J.Molbiopara.2020.111276  0.59
2018 Callanan MK, Habibi SA, Law WJ, Nazareth K, Komuniecki RL, Forrester SG. Investigating the function and possible biological role of an acetylcholine-gated chloride channel subunit (ACC-1) from the parasitic nematode Haemonchus contortus. International Journal For Parasitology. Drugs and Drug Resistance. PMID 30401619 DOI: 10.1016/J.Ijpddr.2018.10.010  0.602
2018 Foster J, Cochrane E, Khatami MH, Habibi SA, de Haan H, Forrester SG. A mutational and molecular dynamics study of the cys-loop GABA receptor Hco-UNC-49 from Haemonchus contortus: Agonist recognition in the nematode GABA receptor family. International Journal For Parasitology. Drugs and Drug Resistance. PMID 30361167 DOI: 10.1016/J.Ijpddr.2018.10.001  0.502
2018 Habibi SA, Callanan M, Forrester SG. Molecular and pharmacological characterization of an acetylcholine-gated chloride channel (ACC-2) from the parasitic nematode Haemonchus contortus. International Journal For Parasitology. Drugs and Drug Resistance. PMID 30266440 DOI: 10.1016/J.Ijpddr.2018.09.004  0.586
2018 Kwaka A, Khatami MH, Foster J, Cochrane E, Habibi SA, de Haan HW, Forrester SG. Molecular characterization of binding loop E in the nematode cys-loop GABA receptor. Molecular Pharmacology. PMID 30194106 DOI: 10.1124/Mol.118.112821  0.524
2017 Abdelmassih SA, Cochrane E, Forrester SG. Evaluating the longevity of surgically extracted Xenopus laevis oocytes for the study of nematode ligand-gated ion channels. Invertebrate Neuroscience : In. 18: 1. PMID 29185074 DOI: 10.1007/S10158-017-0205-Z  0.466
2017 Forrester SG, Foster J, Robert S, Salim L, Desaulniers JP. Efficient synthesis of the GABAA receptor agonist trans-4-aminocrotonic acid (TACA). Bioorganic & Medicinal Chemistry Letters. PMID 28838689 DOI: 10.1016/J.Bmcl.2017.07.050  0.347
2016 Duguet TB, Charvet CL, Forrester SG, Wever CM, Dent JA, Neveu C, Beech RN. Recent Duplication and Functional Divergence in Parasitic Nematode Levamisole-Sensitive Acetylcholine Receptors. Plos Neglected Tropical Diseases. 10: e0004826. PMID 27415016 DOI: 10.1371/Journal.Pntd.0004826  0.671
2015 Kaji MD, Kwaka A, Callanan MK, Nusrat H, Desaulniers JP, Forrester SG. A molecular characterization of the agonist binding site of a nematode cys-loop GABA receptor. British Journal of Pharmacology. 172: 3737-47. PMID 25850584 DOI: 10.1111/Bph.13158  0.48
2013 Beech RN, Callanan MK, Rao VT, Dawe GB, Forrester SG. Characterization of cys-loop receptor genes involved in inhibitory amine neurotransmission in parasitic and free living nematodes. Parasitology International. 62: 599-605. PMID 23602737 DOI: 10.1016/J.Parint.2013.03.010  0.716
2012 Siddiqui SZ, Brown DD, Accardi MV, Forrester SG. Hco-LGC-38 is novel nematode cys-loop GABA receptor subunit. Molecular and Biochemical Parasitology. 185: 137-44. PMID 22940478 DOI: 10.1016/J.Molbiopara.2012.08.004  0.525
2012 Accardi MV, Beech RN, Forrester SG. Nematode cys-loop GABA receptors: biological function, pharmacology and sites of action for anthelmintics. Invertebrate Neuroscience : In. 12: 3-12. PMID 22430311 DOI: 10.1007/S10158-012-0129-6  0.695
2012 Brown DD, Siddiqui SZ, Kaji MD, Forrester SG. Pharmacological characterization of the Haemonchus contortus GABA-gated chloride channel, Hco-UNC-49: modulation by macrocyclic lactone anthelmintics and a receptor for piperazine. Veterinary Parasitology. 185: 201-9. PMID 22075040 DOI: 10.1016/J.Vetpar.2011.10.006  0.58
2011 Accardi MV, Forrester SG. The Haemonchus contortus UNC-49B subunit possesses the residues required for GABA sensitivity in homomeric and heteromeric channels. Molecular and Biochemical Parasitology. 178: 15-22. PMID 21524670 DOI: 10.1016/J.Molbiopara.2011.04.002  0.5
2010 Rao VT, Accardi MV, Siddiqui SZ, Beech RN, Prichard RK, Forrester SG. Characterization of a novel tyramine-gated chloride channel from Haemonchus contortus. Molecular and Biochemical Parasitology. 173: 64-8. PMID 20471431 DOI: 10.1016/J.Molbiopara.2010.05.005  0.721
2010 Beech R, Levitt N, Cambos M, Zhou S, Forrester SG. Association of ion-channel genotype and macrocyclic lactone sensitivity traits in Haemonchus contortus. Molecular and Biochemical Parasitology. 171: 74-80. PMID 20211658 DOI: 10.1016/J.Molbiopara.2010.02.004  0.644
2010 Siddiqui SZ, Brown DD, Rao VT, Forrester SG. An UNC-49 GABA receptor subunit from the parasitic nematode Haemonchus contortus is associated with enhanced GABA sensitivity in nematode heteromeric channels. Journal of Neurochemistry. 113: 1113-22. PMID 20180830 DOI: 10.1111/J.1471-4159.2010.06651.X  0.529
2009 Rao VT, Siddiqui SZ, Prichard RK, Forrester SG. A dopamine-gated ion channel (HcGGR3*) from Haemonchus contortus is expressed in the cervical papillae and is associated with macrocyclic lactone resistance. Molecular and Biochemical Parasitology. 166: 54-61. PMID 19428673 DOI: 10.1016/J.Molbiopara.2009.02.011  0.531
2004 Forrester SG, Beech RN, Prichard RK. Agonist enhacement of macrocyclic lactone activity at a glutamate-gated chloride channel subunit from Haemonchus contortus. Biochemical Pharmacology. 67: 1019-24. PMID 15006538 DOI: 10.1016/J.Bcp.2003.08.047  0.703
2003 Forrester SG, Prichard RK, Dent JA, Beech RN. Haemonchus contortus: HcGluCla expressed in Xenopus oocytes forms a glutamate-gated ion channel that is activated by ibotenate and the antiparasitic drug ivermectin. Molecular and Biochemical Parasitology. 129: 115-21. PMID 12798512 DOI: 10.1016/S0166-6851(03)00102-6  0.691
2002 Forrester SG, Prichard RK, Beech RN. A glutamate-gated chloride channel subunit from Haemonchus contortus: expression in a mammalian cell line, ligand binding, and modulation of anthelmintic binding by glutamate. Biochemical Pharmacology. 63: 1061-8. PMID 11931838 DOI: 10.1016/S0006-2952(02)00852-3  0.686
1999 Forrester SG, Hamdan FF, Prichard RK, Beech RN. Cloning, sequencing, and developmental expression levels of a novel glutamate-gated chloride channel homologue in the parasitic nematode Haemonchus contortus. Biochemical and Biophysical Research Communications. 254: 529-34. PMID 9920773 DOI: 10.1006/Bbrc.1998.0106  0.695
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