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Nathan G. Skene - Publications

Affiliations: 
Wellcome Trust Sanger Institute, England, United Kingdom 
Area:
Transcriptomics
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 Khouri-Farah N, Winchester EW, Schilder BM, Robinson K, Curtis SW, Skene NG, Leslie-Clarkson EJ, Cotney J. Gene expression patterns of the developing human face at single cell resolution reveal cell type contributions to normal facial variation and disease risk. Biorxiv : the Preprint Server For Biology. PMID 39868299 DOI: 10.1101/2025.01.18.633396  0.366
2022 Wahedi A, Soondram C, Murphy AE, Skene N, Rahman S. Transcriptomic analyses reveal neuronal specificity of Leigh syndrome associated genes. Journal of Inherited Metabolic Disease. PMID 36502462 DOI: 10.1002/jimd.12578  0.335
2020 Byrne EM, Zhu Z, Qi T, Skene NG, Bryois J, Pardinas AF, Stahl E, Smoller JW, Rietschel M, Owen MJ, Walters JTR, O'Donovan MC, McGrath JG, et al. Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders. Molecular Psychiatry. PMID 32398722 DOI: 10.1038/S41380-020-0705-9  0.648
2020 Bryois J, Skene NG, Hansen TF, Kogelman LJA, Watson HJ, Liu Z, Brueggeman L, Breen G, Bulik CM, Arenas E, Hjerling-Leffler J, Sullivan PF. Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease. Nature Genetics. PMID 32341526 DOI: 10.1038/S41588-020-0610-9  0.723
2020 Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, ... ... Skene NG, et al. Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk. Nature Genetics. PMID 32029921 DOI: 10.1038/S41588-019-0573-X  0.655
2019 Hill WD, Davies NM, Ritchie SJ, Skene NG, Bryois J, Bell S, Di Angelantonio E, Roberts DJ, Xueyi S, Davies G, Liewald DCM, Porteous DJ, Hayward C, Butterworth AS, McIntosh AM, et al. Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income. Nature Communications. 10: 5741. PMID 31844048 DOI: 10.1038/S41467-019-13585-5  0.424
2019 Qian X, Harris KD, Hauling T, Nicoloutsopoulos D, Muñoz-Manchado AB, Skene N, Hjerling-Leffler J, Nilsson M. Probabilistic cell typing enables fine mapping of closely related cell types in situ. Nature Methods. PMID 31740815 DOI: 10.1038/S41592-019-0631-4  0.792
2019 Jansen PR, Watanabe K, Stringer S, Skene N, Bryois J, Hammerschlag AR, de Leeuw CA, Benjamins JS, Muñoz-Manchado AB, Nagel M, Savage JE, Tiemeier H, White T, Tung JY, et al. Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways. Nature Genetics. PMID 30804565 DOI: 10.1038/S41588-018-0333-3  0.804
2019 Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, ... ... Skene NG, et al. Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk. Nature Genetics. PMID 30617256 DOI: 10.1038/S41588-018-0311-9  0.672
2019 Jansen P, Watanabe K, Stringer S, Skene N, Bryois J, Muñoz-Manchado A, Tung J, Hinds D, Vacic V, Sullivan P, Polderman T, Smit A, Hjerling-Leffler J, van Someren E, Posthuma D. 65GENOME-WIDE ANALYSIS OF INSOMNIA AND SLEEP-RELATED TRAITS IN OVER 1 MILLION INDIVIDUALS IDENTIFIES NOVEL GENES AND PATHWAYS European Neuropsychopharmacology. 29: S1104-S1105. DOI: 10.1016/J.Euroneuro.2018.08.072  0.761
2019 Coleman J, Bryois J, Gaspar H, Jansen P, Savage J, Skene N, Plomin R, Hjerling-Leffler J, Sullivan P, Posthuma D, Breen G. Functional Consequences Of Genetic Loci Associated With Iq In A Meta-Analysis Of 87,740 Individuals European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.051  0.745
2018 Muñoz-Manchado AB, Bengtsson Gonzales C, Zeisel A, Munguba H, Bekkouche B, Skene NG, Lönnerberg P, Ryge J, Harris KD, Linnarsson S, Hjerling-Leffler J. Diversity of Interneurons in the Dorsal Striatum Revealed by Single-Cell RNA Sequencing and PatchSeq. Cell Reports. 24: 2179-2190.e7. PMID 30134177 DOI: 10.1016/J.Celrep.2018.07.053  0.695
2018 Zeisel A, Hochgerner H, Lönnerberg P, Johnsson A, Memic F, van der Zwan J, Häring M, Braun E, Borm LE, La Manno G, Codeluppi S, Furlan A, Lee K, Skene N, Harris KD, et al. Molecular Architecture of the Mouse Nervous System. Cell. 174: 999-1014.e22. PMID 30096314 DOI: 10.1016/J.Cell.2018.06.021  0.776
2018 Zhu F, Cizeron M, Qiu Z, Benavides-Piccione R, Kopanitsa MV, Skene NG, Koniaris B, DeFelipe J, Fransén E, Komiyama NH, Grant SGN. Architecture of the Mouse Brain Synaptome. Neuron. PMID 30078578 DOI: 10.1016/J.Neuron.2018.07.007  0.74
2018 Savage JE, Jansen PR, Stringer S, Watanabe K, Bryois J, de Leeuw CA, Nagel M, Awasthi S, Barr PB, Coleman JRI, Grasby KL, Hammerschlag AR, Kaminski JA, Karlsson R, Krapohl E, ... ... Skene NG, et al. Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature Genetics. PMID 29942086 DOI: 10.1038/S41588-018-0152-6  0.802
2018 Nagel M, Jansen PR, Stringer S, Watanabe K, de Leeuw CA, Bryois J, Savage JE, Hammerschlag AR, Skene NG, Muñoz-Manchado AB, White T, Tiemeier H, Linnarsson S, Hjerling-Leffler J, et al. Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. Nature Genetics. PMID 29942085 DOI: 10.1038/S41588-018-0151-7  0.789
2018 Harris KD, Hochgerner H, Skene NG, Magno L, Katona L, Bengtsson Gonzales C, Somogyi P, Kessaris N, Linnarsson S, Hjerling-Leffler J. Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics. Plos Biology. 16: e2006387. PMID 29912866 DOI: 10.1371/Journal.Pbio.2006387  0.758
2018 Skene NG, Bryois J, Bakken TE, Breen G, Crowley JJ, Gaspar HA, Giusti-Rodriguez P, Hodge RD, Miller JA, Muñoz-Manchado AB, O'Donovan MC, Owen MJ, Pardiñas AF, Ryge J, Walters JTR, et al. Genetic identification of brain cell types underlying schizophrenia. Nature Genetics. PMID 29785013 DOI: 10.1038/s41588-018-0129-5  0.798
2018 Coleman JRI, Bryois J, Gaspar HA, Jansen PR, Savage JE, Skene N, Plomin R, Muñoz-Manchado AB, Linnarsson S, Crawford G, Hjerling-Leffler J, Sullivan PF, Posthuma D, Breen G. Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals. Molecular Psychiatry. PMID 29520040 DOI: 10.1038/S41380-018-0040-6  0.806
2018 Savage JE, Jansen PR, Stringer S, Watanabe K, Bryois J, Leeuw CAd, Nagel M, Awasthi S, Barr PB, Coleman JRI, Grasby KL, Hammerschlag AR, Kaminski J, Karlsson R, Krapohl E, ... ... Skene N, et al. GWAS meta-analysis (N=279,930) identifies new genes and functional links to general cognitive ability Human Genomics. 12. DOI: 10.1186/S40246-018-0138-6  0.755
2017 Roy M, Sorokina O, Skene N, Simonnet C, Mazzo F, Zwart R, Sher E, Smith C, Armstrong JD, Grant SGN. Proteomic analysis of postsynaptic proteins in regions of the human neocortex. Nature Neuroscience. PMID 29203896 DOI: 10.1038/S41593-017-0025-9  0.742
2017 Skene NG, Roy M, Grant SG. A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia. Elife. 6. PMID 28893375 DOI: 10.7554/Elife.17915  0.603
2016 Skene NG, Grant SG. Identification of Vulnerable Cell Types in Major Brain Disorders Using Single Cell Transcriptomes and Expression Weighted Cell Type Enrichment. Frontiers in Neuroscience. 10: 16. PMID 26858593 DOI: 10.3389/Fnins.2016.00016  0.66
2013 Skrzypiec AE, Shah RS, Schiavon E, Baker E, Skene N, Pawlak R, Mucha M. Stress-induced lipocalin-2 controls dendritic spine formation and neuronal activity in the amygdala. Plos One. 8: e61046. PMID 23593384 DOI: 10.1371/Journal.Pone.0061046  0.343
2012 Coba MP, Komiyama NH, Nithianantharajah J, Kopanitsa MV, Indersmitten T, Skene NG, Tuck EJ, Fricker DG, Elsegood KA, Stanford LE, Afinowi NO, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG. TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 13987-99. PMID 23035106 DOI: 10.1523/Jneurosci.2433-12.2012  0.725
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