Ryan M. Drenan - Publications

Affiliations: 
Purdue University, West Lafayette, IN, United States 
Area:
nicotinic receptors, dopamine, neuroscience

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Arvin MC, Jin XT, Yan Y, Wang Y, Ramsey MD, Kim VJ, Beckley NA, Henry BA, Drenan RM. Chronic nicotine exposure alters the neurophysiology of habenulo-interpeduncular circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30867261 DOI: 10.1523/JNEUROSCI.2816-18.2019  1
2019 Arvin MC, Wokosin DL, Banala S, Lavis LD, Drenan RM. Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine. Journal of Visualized Experiments : Jove. PMID 30735191 DOI: 10.3791/58873  1
2018 Yan Y, Peng C, Arvin MC, Jin XT, Kim VJ, Ramsey MD, Wang Y, Banala S, Wokosin DL, McIntosh JM, Lavis LD, Drenan RM. Nicotinic Cholinergic Receptors in VTA Glutamate Neurons Modulate Excitatory Transmission. Cell Reports. 23: 2236-2244. PMID 29791835 DOI: 10.1016/j.celrep.2018.04.062  1
2018 Peng C, Yan Y, Kim VJ, Engle SE, Berry JN, McIntosh JM, Neve RL, Drenan RM. Gene Editing Vectors for Studying Nicotinic Acetylcholine Receptors in Cholinergic Transmission. The European Journal of Neuroscience. PMID 29779223 DOI: 10.1111/ejn.13957  1
2018 Banala S, Arvin MC, Bannon NM, Jin XT, Macklin JJ, Wang Y, Peng C, Zhao G, Marshall JJ, Gee KR, Wokosin DL, Kim VJ, McIntosh JM, Contractor A, Lester HA, ... ... Drenan RM, et al. Photoactivatable drugs for nicotinic optopharmacology. Nature Methods. PMID 29578537 DOI: 10.1038/nmeth.4637  1
2017 Parker RL, O'Neill HC, Henley BM, Wageman CR, Drenan RM, Marks MJ, Miwa JM, Grady SR, Lester HA. Deletion of lynx1 reduces the function of α6* nicotinic receptors. Plos One. 12: e0188715. PMID 29206881 DOI: 10.1371/journal.pone.0188715  1
2017 Arias HR, Jin X, Feuerbach D, Drenan RM. Selectivity of coronaridine congeners at nicotinic acetylcholine receptors and inhibitory activity on mouse medial habenula. The International Journal of Biochemistry & Cell Biology. PMID 29042244 DOI: 10.1016/j.biocel.2017.10.006  0.36
2017 Peng C, Engle SE, Yan Y, Weera MM, Berry JN, Arvin MC, Zhao G, McIntosh JM, Chester JA, Drenan RM. Altered nicotine reward-associated behavior following α4 nAChR subunit deletion in ventral midbrain. Plos One. 12: e0182142. PMID 28759616 DOI: 10.1371/journal.pone.0182142  1
2017 Hurtado-Zavala JI, Ramachandran B, Ahmed S, Halder R, Bolleyer C, Awasthi A, Stahlberg MA, Wagener RJ, Anderson K, Drenan RM, Lester HA, Miwa JM, Staiger JF, Fischer A, Dean C. TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus. Nature Communications. 8: 15878. PMID 28722015 DOI: 10.1038/ncomms15878  1
2015 Shih PY, McIntosh JM, Drenan RM. Nicotine Dependence Reveals Distinct Responses from Neurons and Their Resident Nicotinic Receptors in Medial Habenula. Molecular Pharmacology. 88: 1035-44. PMID 26429939 DOI: 10.1124/mol.115.101444  1
2015 Berry JN, Engle SE, Michael McIntosh J, Drenan RM. α6-Containing Nicotinic Acetylcholine Receptors in Midbrain Dopamine Neurons are Poised to Govern Dopamine-Mediated Behaviors and Synaptic Plasticity. Neuroscience. PMID 26210579 DOI: 10.1016/j.neuroscience.2015.07.052  1
2015 Wieskopf JS, Mathur J, Limapichat W, Post MR, Al-Qazzaz M, Sorge RE, Martin LJ, Zaykin DV, Smith SB, Freitas K, Austin JS, Dai F, Zhang J, Marcovitz J, Tuttle AH, ... ... Drenan RM, et al. The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. Science Translational Medicine. 7: 287ra72. PMID 25972004 DOI: 10.1126/scitranslmed.3009986  1
2015 Bordia T, McGregor M, McIntosh JM, Drenan RM, Quik M. Evidence for a role for α6(∗) nAChRs in l-dopa-induced dyskinesias using Parkinsonian α6(∗) nAChR gain-of-function mice. Neuroscience. 295: 187-97. PMID 25813704 DOI: 10.1016/j.neuroscience.2015.03.040  1
2015 Engle SE, McIntosh JM, Drenan RM. Nicotine and ethanol cooperate to enhance ventral tegmental area AMPA receptor function via α6-containing nicotinic receptors. Neuropharmacology. 91: 13-22. PMID 25484253 DOI: 10.1016/j.neuropharm.2014.11.014  1
2014 Shih PY, Engle SE, Oh G, Deshpande P, Puskar NL, Lester HA, Drenan RM. Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9789-802. PMID 25031416 DOI: 10.1523/JNEUROSCI.0476-14.2014  1
2014 Henderson BJ, Srinivasan R, Nichols WA, Dilworth CN, Gutierrez DF, Mackey ED, McKinney S, Drenan RM, Richards CI, Lester HA. Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors. The Journal of General Physiology. 143: 51-66. PMID 24378908 DOI: 10.1085/jgp.201311102  1
2014 Wang Y, Lee JW, Oh G, Grady SR, McIntosh JM, Brunzell DH, Cannon JR, Drenan RM. Enhanced synthesis and release of dopamine in transgenic mice with gain-of-function α6* nAChRs. Journal of Neurochemistry. 129: 315-27. PMID 24266758 DOI: 10.1111/jnc.12616  1
2013 Engle SE, Shih PY, McIntosh JM, Drenan RM. α4α6β2* nicotinic acetylcholine receptor activation on ventral tegmental area dopamine neurons is sufficient to stimulate a depolarizing conductance and enhance surface AMPA receptor function. Molecular Pharmacology. 84: 393-406. PMID 23788655 DOI: 10.1124/mol.113.087346  1
2013 Powers MS, Broderick HJ, Drenan RM, Chester JA. Nicotinic acetylcholine receptors containing α6 subunits contribute to alcohol reward-related behaviours. Genes, Brain, and Behavior. 12: 543-53. PMID 23594044 DOI: 10.1111/gbb.12042  1
2012 Engle SE, Broderick HJ, Drenan RM. Local application of drugs to study nicotinic acetylcholine receptor function in mouse brain slices. Journal of Visualized Experiments : Jove. e50034. PMID 23128482 DOI: 10.3791/50034  1
2012 Drenan RM, Lester HA. Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutations. Pharmacological Reviews. 64: 869-79. PMID 22885704 DOI: 10.1124/pr.111.004671  1
2012 Mackey ED, Engle SE, Kim MR, O'Neill HC, Wageman CR, Patzlaff NE, Wang Y, Grady SR, McIntosh JM, Marks MJ, Lester HA, Drenan RM. α6* nicotinic acetylcholine receptor expression and function in a visual salience circuit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10226-37. PMID 22836257 DOI: 10.1523/JNEUROSCI.0007-12.2012  1
2012 Cohen BN, Mackey ED, Grady SR, McKinney S, Patzlaff NE, Wageman CR, McIntosh JM, Marks MJ, Lester HA, Drenan RM. Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior. Neuroscience. 200: 31-41. PMID 22079576 DOI: 10.1016/j.neuroscience.2011.10.047  1
2011 Xiao C, Srinivasan R, Drenan RM, Mackey ED, McIntosh JM, Lester HA. Characterizing functional α6β2 nicotinic acetylcholine receptors in vitro: mutant β2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells. Biochemical Pharmacology. 82: 852-61. PMID 21609715 DOI: 10.1016/j.bcp.2011.05.005  1
2010 Gunapala KM, Chang D, Hsu CT, Manaye K, Drenan RM, Switzer RC, Steele AD. Striatal pathology underlies prion infection-mediated hyperactivity in mice. Prion. 4: 302-15. PMID 20948312 DOI: 10.4161/pri.4.4.13721  1
2010 Drenan RM, Grady SR, Steele AD, McKinney S, Patzlaff NE, McIntosh JM, Marks MJ, Miwa JM, Lester HA. Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9877-89. PMID 20660270 DOI: 10.1523/JNEUROSCI.2056-10.2010  1
2010 Grady SR, Drenan RM, Breining SR, Yohannes D, Wageman CR, Fedorov NB, McKinney S, Whiteaker P, Bencherif M, Lester HA, Marks MJ. Structural differences determine the relative selectivity of nicotinic compounds for native alpha 4 beta 2*-, alpha 6 beta 2*-, alpha 3 beta 4*- and alpha 7-nicotine acetylcholine receptors. Neuropharmacology. 58: 1054-66. PMID 20114055 DOI: 10.1016/j.neuropharm.2010.01.013  1
2008 Drenan RM, Grady SR, Whiteaker P, McClure-Begley T, McKinney S, Miwa JM, Bupp S, Heintz N, McIntosh JM, Bencherif M, Marks MJ, Lester HA. In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors. Neuron. 60: 123-36. PMID 18940593 DOI: 10.1016/j.neuron.2008.09.009  1
2008 Drenan RM, Nashmi R, Imoukhuede P, Just H, McKinney S, Lester HA. Subcellular trafficking, pentameric assembly, and subunit stoichiometry of neuronal nicotinic acetylcholine receptors containing fluorescently labeled alpha6 and beta3 subunits. Molecular Pharmacology. 73: 27-41. PMID 17932221 DOI: 10.1124/mol.107.039180  1
2007 Osei-Owusu P, Sun X, Drenan RM, Steinberg TH, Blumer KJ. Regulation of RGS2 and second messenger signaling in vascular smooth muscle cells by cGMP-dependent protein kinase. The Journal of Biological Chemistry. 282: 31656-65. PMID 17681944 DOI: 10.1074/jbc.M706360200  1
2006 Drenan RM, Doupnik CA, Jayaraman M, Buchwalter AL, Kaltenbronn KM, Huettner JE, Linder ME, Blumer KJ. R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism. The Journal of Biological Chemistry. 281: 28222-31. PMID 16867977 DOI: 10.1074/jbc.M604428200  1
2005 Drenan RM, Doupnik CA, Boyle MP, Muglia LJ, Huettner JE, Linder ME, Blumer KJ. Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family. The Journal of Cell Biology. 169: 623-33. PMID 15897264 DOI: 10.1083/jcb.200502007  1
2004 Drenan RM, Liu X, Bertram PG, Zheng XF. FKBP12-rapamycin-associated protein or mammalian target of rapamycin (FRAP/mTOR) localization in the endoplasmic reticulum and the Golgi apparatus. The Journal of Biological Chemistry. 279: 772-8. PMID 14578359 DOI: 10.1074/jbc.M305912200  1
2003 Tsang CK, Bertram PG, Ai W, Drenan R, Zheng XF. Chromatin-mediated regulation of nucleolar structure and RNA Pol I localization by TOR. The Embo Journal. 22: 6045-56. PMID 14609951 DOI: 10.1093/emboj/cdg578  1
2002 Choi JH, Bertram PG, Drenan R, Carvalho J, Zhou HH, Zheng XF. The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinase. Embo Reports. 3: 988-94. PMID 12231510 DOI: 10.1093/embo-reports/kvf197  1
2001 Ostrom RS, Gregorian C, Drenan RM, Xiang Y, Regan JW, Insel PA. Receptor number and caveolar co-localization determine receptor coupling efficiency to adenylyl cyclase. The Journal of Biological Chemistry. 276: 42063-9. PMID 11533056 DOI: 10.1074/jbc.M105348200  1
2001 Ostrom RS, Gregorian C, Drenan RM, Gabot K, Rana BK, Insel PA. Key role for constitutive cyclooxygenase-2 of MDCK cells in basal signaling and response to released ATP. American Journal of Physiology. Cell Physiology. 281: C524-31. PMID 11443051  1
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