John Carling Roder, Ph.D. - Related publications

Samuel Lunenfeld Research Institute Icahn School of Medicine at Mount Sinai, New York, NY, United States 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Li Y, Li J, Yuan Q, Bian X, Long F, Duan R, Gao F, Gao S, Wei S, Wang A, Liu A, Li X, Sun W, Liu Q. Deficiency in WDFY4 reduces the number of CD8 T cells via reactive oxygen species-induced apoptosis. Molecular Immunology. 139: 131-138. PMID 34482201 DOI: 10.1016/j.molimm.2021.08.022   
2021 Martínez-Blanco Á, Domínguez-Pantoja M, Botía-Sánchez M, Pérez-Cabrera S, Bello-Iglesias N, Carrillo-Rodríguez P, Martin-Morales N, Lario-Simón A, Pérez-Sánchez-Cañete MM, Montosa-Hidalgo L, Guerrero-Fernández S, Longobardo-Polanco VM, Redondo-Sánchez S, Cornet-Gomez A, Torres-Sáez M, et al. CD38 Deficiency Ameliorates Chronic Graft--Host Disease Murine Lupus a B-Cell-Dependent Mechanism. Frontiers in Immunology. 12: 713697. PMID 34504495 DOI: 10.3389/fimmu.2021.713697   
2021 Corselli M, Saksena S, Nakamoto M, Lomas WE, Taylor I, Chattopadhyay PK. Single cell multiomic analysis of T cell exhaustion in vitro. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 34390166 DOI: 10.1002/cyto.a.24496   
2021 Xu H, Yu J, Cui J, Chen Z, Zhang X, Zou Y, Du Y, Li Y, Le S, Jiang L, Xia J, Wu J. Ablation of Survivin in T Cells Attenuates Acute Allograft Rejection after Murine Heterotopic Heart Transplantation by Inducing Apoptosis. Frontiers in Immunology. 12: 710904. PMID 34421916 DOI: 10.3389/fimmu.2021.710904   
2021 Mo LH, Han HY, Jin QR, Song YN, Wu GH, Zhang Y, Yang LT, Liu T, Liu ZG, Feng Y, Yang PC. T cell activator-carrying extracellular vesicles induce antigen specific regulatory T cells. Clinical and Experimental Immunology. PMID 34418066 DOI: 10.1111/cei.13655   
2021 Yang L, Chen W, Li L, Xiao Y, Fan S, Zhang Q, Xia T, Li M, Hong Y, Zhao T, Li Q, Liu WH, Xiao N. Ddb1 Is Essential for the Expansion of CD4 Helper T Cells by Regulating Cell Cycle Progression and Cell Death. Frontiers in Immunology. 12: 722273. PMID 34526995 DOI: 10.3389/fimmu.2021.722273   
2021 Dubois S, Waldmann TA, Müller JR. Effective Cytotoxicity of Dendritic Cells against Established T Cell Lymphomas in Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 34330751 DOI: 10.4049/jimmunol.2001123   
2021 Hu W, Wang ZM, Feng Y, Schizas M, Hoyos BE, van der Veeken J, Verter JG, Bou-Puerto R, Rudensky AY. Regulatory T cells function in established systemic inflammation and reverse fatal autoimmunity. Nature Immunology. PMID 34426690 DOI: 10.1038/s41590-021-01001-4   
2021 Mo F, Yu Z, Li P, Oh J, Spolski R, Zhao L, Glassman CR, Yamamoto TN, Chen Y, Golebiowski FM, Hermans D, Majri-Morrison S, Picton LK, Liao W, Ren M, et al. An engineered IL-2 partial agonist promotes CD8 T cell stemness. Nature. PMID 34526724 DOI: 10.1038/s41586-021-03861-0   
2021 Luo M, Lai W, He Z, Wu L. Development of an Optimized Culture System for Generating Mouse Alveolar Macrophage-like Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 34400525 DOI: 10.4049/jimmunol.2100185   
2021 Camaya I, Mok TY, Lund M, To J, Braidy N, Robinson MW, Santos J, O'Brien B, Donnelly S. The parasite-derived peptide FhHDM-1 activates the PI3K/Akt pathway to prevent cytokine-induced apoptosis of β-cells. Journal of Molecular Medicine (Berlin, Germany). PMID 34374810 DOI: 10.1007/s00109-021-02122-x   
2021 Wright JA, Bazile C, Clark ES, Carlesso G, Boucher J, Kleiman E, Mahmoud T, Cheng LI, López-Rodríguez DM, Satterthwaite AB, Altman NH, Greidinger EL, Khan WN. Impaired B Cell Apoptosis Results in Autoimmunity That Is Alleviated by Ablation of Btk. Frontiers in Immunology. 12: 705307. PMID 34512628 DOI: 10.3389/fimmu.2021.705307   
2021 Osman A, Yan B, Li Y, Pavelko KD, Quandt J, Saadalla A, Singh MP, Kazemian M, Gounari F, Khazaie K. TCF-1 controls T cell functions that regulate inflammation, CD8 T cell cytotoxicity and severity of colon cancer. Nature Immunology. PMID 34385712 DOI: 10.1038/s41590-021-00987-1   
2021 Miller IC, Zamat A, Sun LK, Phuengkham H, Harris AM, Gamboa L, Yang J, Murad JP, Priceman SJ, Kwong GA. Enhanced intratumoural activity of CAR T cells engineered to produce immunomodulators under photothermal control. Nature Biomedical Engineering. PMID 34385695 DOI: 10.1038/s41551-021-00781-2   
2021 Shaw AM, Qasem A, Naser SA. Modulation of Function by Spermidine in CRISPR-Cas9-Edited T-Cells Associated with Crohn's Disease and Rheumatoid Arthritis. International Journal of Molecular Sciences. 22. PMID 34445589 DOI: 10.3390/ijms22168883   
2021 Wang F, Zhang Y, Yu X, Teng XL, Ding R, Hu Z, Wang A, Wang Z, Ye Y, Zou Q. ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells. The Journal of Clinical Investigation. PMID 34403361 DOI: 10.1172/JCI144318   
2021 Wang Z, Xie L, Ding G, Song S, Chen L, Li G, Xia M, Han D, Zheng Y, Liu J, Xiao T, Zhang H, Huang Y, Li Y, Huang M. Single-cell RNA sequencing of peripheral blood mononuclear cells from acute Kawasaki disease patients. Nature Communications. 12: 5444. PMID 34521850 DOI: 10.1038/s41467-021-25771-5   
2021 Dahotre SN, Romanov AM, Su FY, Kwong GA. Synthetic Antigen-Presenting Cells for Adoptive T Cell Therapy. Advanced Therapeutics. 4. PMID 34541300 DOI: 10.1002/adtp.202100034   
2021 Chaffey JR, Young J, Leslie KA, Partridge K, Akhbari P, Dhayal S, Hill JL, Wedgwood KCA, Burnett E, Russell MA, Richardson SJ, Morgan NG. Investigation of the utility of the 1.1B4 cell as a model human beta cell line for study of persistent enteroviral infection. Scientific Reports. 11: 15624. PMID 34341375 DOI: 10.1038/s41598-021-94878-y   
2021 Wang J, Cao Z, Wang P, Zhang X, Tang J, He Y, Huang Z, Mao X, Shi S, Kou X. Apoptotic Extracellular Vesicles Ameliorate Multiple Myeloma by Restoring Fas-Mediated Apoptosis. Acs Nano. PMID 34506129 DOI: 10.1021/acsnano.1c03517   
2021 Bhagyaraj E, Wang H, Yang X, Hoffman C, Akgul A, Goodwin ZI, Pascual DW. Mucosal Vaccination Primes NK Cell-Dependent Development of CD8 T Cells Against Pulmonary Infection. Frontiers in Immunology. 12: 697953. PMID 34305935 DOI: 10.3389/fimmu.2021.697953   
2021 Watts D, Janßen M, Jaykar M, Palmucci F, Weigelt M, Petzold C, Hommel A, Sparwasser T, Bonifacio E, Kretschmer K. Transient Depletion of Foxp3 Regulatory T Cells Selectively Promotes Aggressive β Cell Autoimmunity in Genetically Susceptible DEREG Mice. Frontiers in Immunology. 12: 720133. PMID 34447385 DOI: 10.3389/fimmu.2021.720133   
2021 Bonte S, de Munter S, Billiet L, Goetgeluk G, Ingels J, Jansen H, Pille M, de Cock L, Weening K, Taghon T, Leclercq G, Vandekerckhove B, Kerre T. OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality. Oncoimmunology. 10: 1954800. PMID 34367734 DOI: 10.1080/2162402X.2021.1954800   
2021 Yu M, Su Z, Huang X, Zhou Y, Zhang X, Wang B, Wang Z, Liu Y, Xing N, Xia M, Wang X. Histone methyltransferase Ezh2 negatively regulates NK cell terminal maturation and function. Journal of Leukocyte Biology. PMID 34425630 DOI: 10.1002/JLB.1MA0321-155RR   
2021 Li H, Gao Y, Xie L, Wang R, Duan R, Li Z, Chen B, Zhu L, Wang X, Su W. Prednisone Reprograms the Transcriptional Immune Cell Landscape in CNS Autoimmune Disease. Frontiers in Immunology. 12: 739605. PMID 34484247 DOI: 10.3389/fimmu.2021.739605   
2021 Lynall ME, Kigar SL, Lehmann ML, DePuyt AE, Tuong ZK, Listwak SJ, Elkahloun AG, Bullmore ET, Herkenham M, Clatworthy MR. B-cells are abnormal in psychosocial stress and regulate meningeal myeloid cell activation. Brain, Behavior, and Immunity. PMID 34371135 DOI: 10.1016/j.bbi.2021.08.002   
2021 Tani H, Li B, Kusu T, Okumura R, Nishimura J, Okuzaki D, Motooka D, Arakawa S, Mori A, Yoshihara T, Ogino T, Tsai SH, Furuta Y, Muneta M, Nakamura S, et al. The ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis through modulation of P2X4 receptor-dependent metabolism in myeloid cells. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34548395 DOI: 10.1073/pnas.2100594118   
2021 Elmentaite R, Kumasaka N, Roberts K, Fleming A, Dann E, King HW, Kleshchevnikov V, Dabrowska M, Pritchard S, Bolt L, Vieira SF, Mamanova L, Huang N, Perrone F, Goh Kai'En I, et al. Cells of the human intestinal tract mapped across space and time. Nature. 597: 250-255. PMID 34497389 DOI: 10.1038/s41586-021-03852-1   
2021 Finney J, Kelsoe G. Continuous Culture of Mouse Primary B Lymphocytes by Forced Expression of . Journal of Immunology (Baltimore, Md. : 1950). 207: 1478-1492. PMID 34389622 DOI: 10.4049/jimmunol.2100172   
2021 Gaddis DE, Padgett LE, Wu R, Nguyen A, McSkimming C, Dinh HQ, Araujo DJ, Taylor AM, McNamara CA, Hedrick CC. Atherosclerosis Impairs Naive CD4 T-Cell Responses via Disruption of Glycolysis. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314189. PMID 34320835 DOI: 10.1161/ATVBAHA.120.314189   
2021 Janelle V, Neault M, Lebel MÈ, De Sousa DM, Boulet S, Durrieu L, Carli C, Muzac C, Lemieux S, Labrecque N, Melichar HJ, Mallette FA, Delisle JS. p16 Regulates Cellular Senescence in PD-1-Expressing Human T Cells. Frontiers in Immunology. 12: 698565. PMID 34434190 DOI: 10.3389/fimmu.2021.698565   
2021 Kong W, Dimitri A, Wang W, Jung IY, Ott CJ, Fasolino M, Wang Y, Kulikovskaya I, Gupta M, Yoder T, DeNizio JE, Everett JK, Williams EF, Xu J, Scholler J, et al. BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia. The Journal of Clinical Investigation. 131. PMID 34396987 DOI: 10.1172/JCI145459   
2021 Gao S, Wang Y, Li Y, Xiao D, Lin Y, Chen Y, Cai X. Tetrahedral Framework Nucleic Acids Reestablish Immune Tolerance and Restore Saliva Secretion in a Sjögren's Syndrome Mouse Model. Acs Applied Materials & Interfaces. PMID 34477358 DOI: 10.1021/acsami.1c14861   
2021 Jing Y, Cao M, Zhang B, Long X, Wang X. cDC1 Dependent Accumulation of Memory T Cells Is Required for Chronic Autoimmune Inflammation in Murine Testis. Frontiers in Immunology. 12: 651860. PMID 34381443 DOI: 10.3389/fimmu.2021.651860   
2021 Kan H, Zhang K, Mao A, Geng L, Gao M, Feng L, You Q, Ma X. Single-cell transcriptome analysis reveals cellular heterogeneity in the ascending aortas of normal and high-fat diet-fed mice. Experimental & Molecular Medicine. PMID 34548614 DOI: 10.1038/s12276-021-00671-2   
2021 Petersen B, Kammerer R, Frenzel A, Hassel P, Dau TH, Becker R, Breithaupt A, Ulrich RG, Lucas-Hahn A, Meyers G. Generation and first characterization of TRDC-knockout pigs lacking γδ T cells. Scientific Reports. 11: 14965. PMID 34294758 DOI: 10.1038/s41598-021-94017-7   
2021 Li G, Kolan SS, Guo S, Marciniak K, Kolan P, Malachin G, Grimolizzi F, Haraldsen G, Skålhegg BS. Activated, Pro-Inflammatory Th1, Th17, and Memory CD4+ T Cells and B Cells Are Involved in Delayed-Type Hypersensitivity Arthritis (DTHA) Inflammation and Paw Swelling in Mice. Frontiers in Immunology. 12: 689057. PMID 34408746 DOI: 10.3389/fimmu.2021.689057   
2021 Maradiaga ODH, Mok PL, Sivapragasam G, Samrot AV, Ali Khan MS, Farhana A, Alzahrani B, Tong J, Karuppiah T, Joseph NMS, Subbiah SK. Lipofection of Single Guide RNA Targeting Decreases Proliferation and Migration in Lung Adenocarcinoma Cells. Medicina (Kaunas, Lithuania). 57. PMID 34356991 DOI: 10.3390/medicina57070710   
2021 Zhang X, Ge R, Chen H, Ahiafor M, Liu B, Chen J, Fan X. Follicular Helper CD4 T Cells, Follicular Regulatory CD4 T Cells, and Inducible Costimulator and Their Roles in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis. Mediators of Inflammation. 2021: 2058964. PMID 34552387 DOI: 10.1155/2021/2058964   
2021 Vella JL, Molodtsov A, Angeles CV, Branchini BR, Turk MJ, Huang YH. Dendritic cells maintain anti-tumor immunity by positioning CD8 skin-resident memory T cells. Life Science Alliance. 4. PMID 34362825 DOI: 10.26508/lsa.202101056   
2021 Siddiqi T, Wang X, Blanchard MS, Wagner J, Popplewell L, Budde LE, Stiller T, Clark MC, Lim L, Vyas V, Brown C, Forman SJ. CD19 directed CAR T cell therapy for treatment of primary CNS lymphoma. Blood Advances. PMID 34492703 DOI: 10.1182/bloodadvances.2020004106   
2021 Kim B, Kim HY, Lee WW. Zap70 Regulates TCR-Mediated Zip6 Activation at the Immunological Synapse. Frontiers in Immunology. 12: 687367. PMID 34394081 DOI: 10.3389/fimmu.2021.687367   
2021 Kang E, Kadoch C, Rubenstein JL, Lanier LL, Wells JA. A functional mammalian display screen identifies rare antibodies that stimulate NK cell-mediated cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34330834 DOI: 10.1073/pnas.2104099118   
2021 Banerjee H, Nieves-Rosado H, Kulkarni A, Murter B, McGrath KV, Chandran UR, Chang A, Szymczak-Workman AL, Vujanovic L, Delgoffe GM, Ferris RL, Kane LP. Expression of Tim-3 drives phenotypic and functional changes in Treg cells in secondary lymphoid organs and the tumor microenvironment. Cell Reports. 36: 109699. PMID 34525351 DOI: 10.1016/j.celrep.2021.109699   
2021 Wang B, Wang Y, Sun X, Deng G, Huang W, Wu X, Gu Y, Tian Z, Fan Z, Xu Q, Chen H, Sun Y. CXCR6 is required for antitumor efficacy of intratumoral CD8 T cell. Journal For Immunotherapy of Cancer. 9. PMID 34462326 DOI: 10.1136/jitc-2021-003100   
2021 Majumder S, Jugovic I, Saul D, Bell L, Hundhausen N, Seal R, Beilhack A, Rosenwald A, Mougiakakos D, Berberich-Siebelt F. Rapid and Efficient Gene Editing for Direct Transplantation of Naive Murine Cas9 T Cells. Frontiers in Immunology. 12: 683631. PMID 34367143 DOI: 10.3389/fimmu.2021.683631   
2021 Bigley AB, Spade S, Agha NH, Biswas S, Tang S, Malik MH, Dai L, Masoumi S, Patiño-Escobar B, Hale M, DiPierro G, Martell R, Hann B, Shah N, Wiita AP, et al. FcεRIγ-negative NK cells persist in vivo and enhance efficacy of therapeutic monoclonal antibodies in multiple myeloma. Blood Advances. 5: 3021-3031. PMID 34357379 DOI: 10.1182/bloodadvances.2020002440   
2021 Nagesh R, Kiran Kumar KM, Naveen Kumar M, Patil RH, Sharma SC. Regulation of Jun and Fos AP-1 transcription factors by JNK MAPKs signaling cascade in areca nut extract treated KB cells. Biochemistry and Biophysics Reports. 27: 101090. PMID 34401529 DOI: 10.1016/j.bbrep.2021.101090   
2021 Ng YY, Du Z, Zhang X, Chng WJ, Wang S. CXCR4 and anti-BCMA CAR co-modified natural killer cells suppress multiple myeloma progression in a xenograft mouse model. Cancer Gene Therapy. PMID 34471234 DOI: 10.1038/s41417-021-00365-x   
2021 Leivas A, Valeri A, Córdoba L, García-Ortiz A, Ortiz A, Sánchez-Vega L, Graña-Castro O, Fernández L, Carreño-Tarragona G, Pérez M, Megías D, Paciello ML, Sánchez-Pina J, Pérez-Martínez A, Lee DA, et al. NKG2D-CAR-transduced natural killer cells efficiently target multiple myeloma. Blood Cancer Journal. 11: 146. PMID 34392311 DOI: 10.1038/s41408-021-00537-w