Jorge Mansilla-Soto, Ph.D. - Publications

Affiliations: 
2006 Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Molecular Biology

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Amor C, Feucht J, Leibold J, Ho YJ, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, Peerschke E, Friedman SL, Ponomarev V, et al. Senolytic CAR T cells reverse senescence-associated pathologies. Nature. PMID 32555459 DOI: 10.1038/S41586-020-2403-9  0.354
2019 Hamieh M, Dobrin A, Cabriolu A, van der Stegen SJC, Giavridis T, Mansilla-Soto J, Eyquem J, Zhao Z, Whitlock BM, Miele MM, Li Z, Cunanan KM, Huse M, Hendrickson RC, Wang X, et al. CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape. Nature. PMID 30918399 DOI: 10.1038/S41586-019-1054-1  0.36
2018 Clarke R, Van Der Stegen S, Chang C, Husain M, Lai Y, Peralta E, Stokely L, Abujarour R, Dinella J, Lee T, Pribadi M, Chu H, Truong C, Sabouri-Ghomi M, Meza M, ... ... Mansilla-Soto J, et al. Pluripotent Cell-Derived Off-the-Shelf TCR-Less CAR-Targeted Cytotoxic T Cell Therapeutic for the Allogeneic Treatment of B Cell Malignancies Blood. 132: 4546-4546. DOI: 10.1182/Blood-2018-99-116843  0.374
2018 Clarke RL, Stegen Svd, Lee T, Mansilla-Soto J, Chang C, Sasaki J, Husain M, Peralta E, Hardy I, Ortiz E, Riviere I, Sadelain M, Valamehr B. Abstract LB-108: Generation of off-the-shelf TCR-less CAR-targeted cytotoxic T cells from renewable pluripotent cells for cancer immunotherapy Immunology. 78. DOI: 10.1158/1538-7445.Am2018-Lb-108  0.377
2017 Perna F, Berman SH, Soni RK, Mansilla-Soto J, Eyquem J, Hamieh M, Hendrickson RC, Brennan CW, Sadelain M. Integrating Proteomics and Transcriptomics for Systematic Combinatorial Chimeric Antigen Receptor Therapy of AML. Cancer Cell. 32: 506-519.e5. PMID 29017060 DOI: 10.1016/J.Ccell.2017.09.004  0.323
2017 Eyquem J, Mansilla-Soto J, Giavridis T, van der Stegen SJ, Hamieh M, Cunanan KM, Odak A, Gönen M, Sadelain M. Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection. Nature. PMID 28225754 DOI: 10.1038/Nature21405  0.386
2017 Seyffert M, Glauser DL, Schraner EM, de Oliveira AP, Mansilla-Soto J, Vogt B, Büning H, Linden RM, Ackermann M, Fraefel C. Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication. Plos One. 12: e0170908. PMID 28125695 DOI: 10.1371/Journal.Pone.0170908  0.423
2016 Mansilla-Soto J, Riviere I, Boulad F, Sadelain M. Cell and gene therapy for the beta-thalassemias: advances and prospects. Human Gene Therapy. PMID 27021486 DOI: 10.1089/Hum.2016.037  0.315
2016 Perna F, Berman S, Mansilla-Soto J, Hamieh M, Juthani R, Soni R, Eyquem J, Hendrickson R, Brennan C, Sadelain M. Probing the AML Surfaceome for Chimeric Antigen Receptor (CAR) Targets Blood. 128: 526-526. DOI: 10.1182/Blood.V128.22.526.526  0.371
2016 Stegen SJCvd, Themeli M, Eyquem J, Mansilla-Soto J, Sadelain M. Abstract 2309: T-cell development from T cell-derived induced pluripotent stem cell Cancer Research. 76: 2309-2309. DOI: 10.1158/1538-7445.Am2016-2309  0.363
2016 Eyquem J, Mansilla-Soto J, Odak A, Sadelain M. 274. One-Step Generation of Universal CAR T Cells Molecular Therapy. 24: S109. DOI: 10.1016/S1525-0016(16)33083-0  0.385
2015 Perna F, Vu LP, Themeli M, Kriks S, Hoya-Arias R, Khanin R, Hricik T, Mansilla-Soto J, Papapetrou EP, Levine RL, Studer L, Sadelain M, Nimer SD. The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells. Stem Cell Reports. 4: 658-69. PMID 25754204 DOI: 10.1016/J.Stemcr.2015.02.003  0.344
2015 Mansilla-Soto J, Leifman Y, Sadelain M. 343. Repair of the Sickle-Cell Disease Mutation in Human Stem Cells Using CRISPR/Cas9 and Single-Stranded Oligodeoxynucleotides Molecular Therapy. 23: S137. DOI: 10.1016/S1525-0016(16)33952-1  0.392
2013 Zarate-Perez F, Mansilla-Soto J, Bardelli M, Burgner JW, Villamil-Jarauta M, Kekilli D, Samso M, Linden RM, Escalante CR. Oligomeric properties of adeno-associated virus Rep68 reflect its multifunctionality. Journal of Virology. 87: 1232-41. PMID 23152528 DOI: 10.1128/Jvi.02441-12  0.382
2012 Zarate-Perez F, Bardelli M, Burgner JW, Villamil-Jarauta M, Das K, Kekilli D, Mansilla-Soto J, Linden RM, Escalante CR. The interdomain linker of AAV-2 Rep68 is an integral part of its oligomerization domain: role of a conserved SF3 helicase residue in oligomerization. Plos Pathogens. 8: e1002764. PMID 22719256 DOI: 10.1371/Journal.Ppat.1002764  0.338
2011 Mansilla-Soto J, Rivière I, Sadelain M. Genetic strategies for the treatment of sickle cell anaemia. British Journal of Haematology. 154: 715-27. PMID 21707580 DOI: 10.1111/J.1365-2141.2011.08773.X  0.327
2009 Mansilla-Soto J, Yoon-Robarts M, Rice WJ, Arya S, Escalante CR, Linden RM. DNA structure modulates the oligomerization properties of the AAV initiator protein Rep68. Plos Pathogens. 5: e1000513. PMID 19593381 DOI: 10.1371/Journal.Ppat.1000513  0.478
2004 Sawchuk DJ, Mansilla-Soto J, Alarcon C, Singha NC, Langen H, Bianchi ME, Lees-Miller SP, Nussenzweig MC, Cortes P. Ku70/Ku80 and DNA-dependent protein kinase catalytic subunit modulate RAG-mediated cleavage: implications for the enforcement of the 12/23 rule. The Journal of Biological Chemistry. 279: 29821-31. PMID 15123719 DOI: 10.1074/Jbc.M403706200  0.596
2003 Mansilla-Soto J, Cortes P. VDJ recombination: Artemis and its in vivo role in hairpin opening. The Journal of Experimental Medicine. 197: 543-7. PMID 12615895 DOI: 10.1084/Jem.20022210  0.625
1998 Besmer E, Mansilla-Soto J, Cassard S, Sawchuk DJ, Brown G, Sadofsky M, Lewis SM, Nussenzweig MC, Cortes P. Hairpin coding end opening is mediated by RAG1 and RAG2 proteins. Molecular Cell. 2: 817-28. PMID 9885569 DOI: 10.1016/S1097-2765(00)80296-8  0.612
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