Yu Fukuda, Ph.D. - Publications

Affiliations: 
2008 Pharmaceutical Sciences University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Cell Biology, Physiology Biology

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Gose T, Rasouli A, Dehghani-Ghahnaviyeh S, Wen PC, Wang Y, Lynch J, Fukuda Y, Shafi T, Ford RC, Tajkhorshid E, Schuetz JD. Tumor-acquired somatic mutation affects conformation to abolish ABCG2-mediated drug resistance. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 73: 101066. PMID 38387283 DOI: 10.1016/j.drup.2024.101066  0.601
2024 Su Y, Carter JL, Li X, Fukuda Y, Gray A, Lynch J, Edwards H, Ma J, Schreiner P, Polin L, Kushner J, Dzinic SH, Buck SA, Pruett-Miller SM, Hurrish KH, et al. The imipridone ONC213 targets α-ketoglutarate dehydrogenase to induce mitochondrial stress and suppress oxidative phosphorylation in acute myeloid leukemia. Cancer Research. PMID 38266099 DOI: 10.1158/0008-5472.CAN-23-2659  0.534
2023 Gose T, Aitken HM, Wang Y, Lynch J, Rampersaud E, Fukuda Y, Wills M, Baril SA, Ford RC, Shelat A, Mara MLO, Schuetz JD. The net electrostatic potential and hydration of ABCG2 affect substrate transport. Nature Communications. 14: 5035. PMID 37596258 DOI: 10.1038/s41467-023-40610-5  0.627
2023 Lynch J, Wang Y, Li Y, Kavdia K, Fukuda Y, Ranjit S, Robinson CG, Grace CR, Xia Y, Peng J, Schuetz JD. A PPIX-binding probe facilitates discovery of PPIX-induced cell death modulation by peroxiredoxin. Communications Biology. 6: 673. PMID 37355765 DOI: 10.1038/s42003-023-05024-5  0.537
2021 Ganguly S, Finkelstein D, Shaw TI, Michalek RD, Zorn KM, Ekins S, Yasuda K, Fukuda Y, Schuetz JD, Mukherjee K, Schuetz EG. Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters. Plos One. 16: e0253852. PMID 34255797 DOI: 10.1371/journal.pone.0253852  0.562
2020 Gose T, Shafi T, Fukuda Y, Das S, Wang Y, Allcock A, Gavan McHarg A, Lynch J, Chen T, Tamai I, Shelat A, Ford RC, Schuetz JD. ABCG2 requires a single aromatic amino acid to "clamp" substrates and inhibitors into the binding pocket. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32067270 DOI: 10.1096/Fj.201902338Rr  0.619
2020 Gose T, Shafi T, Fukuda Y, Das S, Wang Y, Lynch J, McHarg AG, Shelat A, Ford RC, Schuetz JD. A Single Amino Acid in ABCG2 is Essential for Clamping Substrates and Inhibitors into the Binding Pocket The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04943  0.548
2019 O'Reilly C, Cho JH, Qi Q, Peters JL, Fukuda Y, Frase S, Peng J, Schuetz JD, Cheng Y, Yoon SO, Han MJ. Corrigendum to "Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles" [379 (2019) 55-64]. Experimental Cell Research. PMID 31079852 DOI: 10.1016/J.Yexcr.2019.05.002  0.524
2019 O'Reilly C, Cho JH, Qi Q, Peters JL, Fukuda Y, Frase S, Peng J, Schuetz JD, Cheng Y, Yoon SO, Han MJ. Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles. Experimental Cell Research. PMID 30922922 DOI: 10.1016/J.Yexcr.2019.03.028  0.566
2019 Gose T, Fukuda Y, Das S, Wang Y, Lynch J, Shelat A, Schuetz JD. Determining the Molecular Characteristics of How Ligands Interact with an ABC Transporter The Faseb Journal. 33. DOI: 10.1096/Fasebj.2019.33.1_Supplement.507.4  0.59
2018 Su Y, Li X, Edwards H, Polin L, Kushner J, Dzinic SH, Hege K, Fukuda Y, Schuetz JD, Allen JE, Stogniew M, Prabhu VV, Taub JW, Lin H, Ge Y. Venetoclax Synergistically Enhances the Antileukemic Activity of Imipridone ONC213, a Novel Imipridone ONC201 Analog, in Acute Myeloid Leukemia Blood. 132: 3936-3936. DOI: 10.1182/Blood-2018-99-116997  0.574
2017 Boswell-Casteel RC, Fukuda Y, Schuetz JD. ABCB6, an ABC Transporter Impacting Drug Response and Disease. The Aaps Journal. 20: 8. PMID 29192381 DOI: 10.1208/S12248-017-0165-6  0.704
2017 Wijaya J, Fukuda Y, Schuetz JD. Obstacles to Brain Tumor Therapy: Key ABC Transporters. International Journal of Molecular Sciences. 18. PMID 29186899 DOI: 10.3390/Ijms18122544  0.588
2017 Pitre A, Ge Y, Lin W, Wang Y, Fukuda Y, Temirov J, Phillips AH, Peters JL, Fan Y, Ma J, Nourse A, Sinha C, Lin H, Kriwacki R, Downing JR, et al. An unexpected protein interaction promotes drug resistance in leukemia. Nature Communications. 8: 1547. PMID 29146910 DOI: 10.1038/S41467-017-01678-Y  0.603
2017 Fukuda Y, Wang Y, Lian S, Lynch J, Nagai S, Fanshawe B, Kandilci A, Janke LJ, Neale G, Fan Y, Sorrentino BP, Roussel MF, Grosveld G, Schuetz JD. Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis. Jci Insight. 2. PMID 28768907 DOI: 10.1172/Jci.Insight.92409  0.604
2016 Fukuda Y, Cheong PL, Lynch J, Brighton C, Frase S, Kargas V, Rampersaud E, Wang Y, Sankaran VG, Yu B, Ney PA, Weiss MJ, Vogel P, Bond PJ, Ford RC, et al. The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6. Nature Communications. 7: 12353. PMID 27507172 DOI: 10.1038/Ncomms12353  0.61
2015 Cheepala SB, Pitre A, Fukuda Y, Takenaka K, Zhang Y, Wang Y, Frase S, Pestina T, Gartner TK, Jackson C, Schuetz JD. ABCC4, a plasma membrane transporter modulating platelet aggregation. Blood. PMID 26405223 DOI: 10.1182/Blood-2014-08-595942  0.573
2015 Morfouace M, Cheepala S, Jackson S, Fukuda Y, Patel YT, Fatima S, Kawauchi D, Shelat AA, Stewart CF, Sorrentino BP, Schuetz JD, Roussel MF. ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy. Cancer Research. PMID 26199091 DOI: 10.1158/0008-5472.Can-15-0030  0.643
2015 Fukuda Y, Lian S, Schuetz JD. Leukemia and ABC Transporters Advances in Cancer Research. 125: 171-196. PMID 25640270 DOI: 10.1016/Bs.Acr.2014.10.006  0.67
2015 Fukuda Y, Wang Y, Nagai S, Fanshawe B, Kandilci A, Zindy F, Janke L, Neale G, Fan Y, Sorrentino B, Roussel M, Grosveld G, Schuetz J. The heme biosynthetic pathway plays a crucial role in N-MYC myeloid leukemias Experimental Hematology. 43: S63. DOI: 10.1016/J.Exphem.2015.06.124  0.532
2013 Fukuda Y, Takenaka K, Sparreboom A, Cheepala SB, Wu CP, Ekins S, Ambudkar SV, Schuetz JD. Human immunodeficiency virus protease inhibitors interact with ATP binding cassette transporter 4/multidrug resistance protein 4: a basis for unanticipated enhanced cytotoxicity. Molecular Pharmacology. 84: 361-71. PMID 23775562 DOI: 10.1124/Mol.113.086967  0.611
2013 Treanor LM, Zhou S, Fukuda Y, Satish N, Finkelstein D, Schuetz JD, Mullighan CG, Sorrentino BP. N-Myc Is Overexpressed In Both Murine and Human Early T-Cell Precursor Leukemia and Is Sufficient To Initiate this Leukemia In Multipotent Primitive Arf-/- thymocytes Blood. 122: 348-348. DOI: 10.1182/Blood.V122.21.348.348  0.564
2012 Ulrich DL, Lynch J, Wang Y, Fukuda Y, Nachagari D, Du G, Sun D, Fan Y, Tsurkan L, Potter PM, Rehg JE, Schuetz JD. ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity. The Journal of Biological Chemistry. 287: 12679-90. PMID 22294697 DOI: 10.1074/Jbc.M111.336180  0.639
2012 Fukuda Y, Schuetz JD. ABC transporters and their role in nucleoside and nucleotide drug resistance Biochemical Pharmacology. 83: 1073-1083. PMID 22285911 DOI: 10.1016/J.Bcp.2011.12.042  0.622
2011 Fukuda Y, Aguilar-Bryan L, Vaxillaire M, Dechaume A, Wang Y, Dean M, Moitra K, Bryan J, Schuetz JD. Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8. The Journal of Biological Chemistry. 286: 8481-92. PMID 21199866 DOI: 10.1074/Jbc.M110.174516  0.637
2009 Lynch J, Fukuda Y, Krishnamurthy P, Du G, Schuetz JD. Cell survival under stress is enhanced by a mitochondrial ATP-binding cassette transporter that regulates hemoproteins. Cancer Research. 69: 5560-7. PMID 19549895 DOI: 10.1158/0008-5472.Can-09-0078  0.647
2006 Krishnamurthy PC, Du G, Fukuda Y, Sun D, Sampath J, Mercer KE, Wang J, Sosa-Pineda B, Murti KG, Schuetz JD. Identification of a mammalian mitochondrial porphyrin transporter. Nature. 443: 586-9. PMID 17006453 DOI: 10.1038/Nature05125  0.645
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