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Brian R. Rosborough, Ph.D. - Publications

Affiliations: 
2013 Immunology University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Immunology
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Yazdani HO, Chen HW, Tohme S, Tai S, van der Windt DJ, Loughran P, Rosborough BR, Sud V, Beer-Stolz D, Turnquist HR, Tsung A, Huang H. IL-33 exacerbates liver sterile inflammation by amplifying neutrophil extracellular trap formation. Journal of Hepatology. PMID 28943296 DOI: 10.1016/J.Jhep.2017.09.010  0.388
2016 Chen LC, Nicholson YT, Rosborough BR, Thomson AW, Raimondi G. A Novel mTORC1-Dependent, Akt-Independent Pathway Differentiates the Gut Tropism of Regulatory and Conventional CD4 T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 27402696 DOI: 10.4049/Jimmunol.1600696  0.576
2015 Raïch-Regué D, Rosborough BR, Watson AR, McGeachy MJ, Turnquist HR, Thomson AW. mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo. Journal of Immunology (Baltimore, Md. : 1950). 194: 4767-76. PMID 25840913 DOI: 10.4049/Jimmunol.1402551  0.671
2014 Rosborough BR, Raïch-Regué D, Liu Q, Venkataramanan R, Turnquist HR, Thomson AW. Adenosine triphosphate-competitive mTOR inhibitors: a new class of immunosuppressive agents that inhibit allograft rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 2173-80. PMID 25307040 DOI: 10.1111/Ajt.12799  0.531
2014 Matta BM, Lott JM, Mathews LR, Liu Q, Rosborough BR, Blazar BR, Turnquist HR. IL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 193: 4010-20. PMID 25217167 DOI: 10.4049/Jimmunol.1400481  0.548
2014 Rosborough BR, Hackstein H, Turnquist HR. A window into immunosuppressant immunoregulation: recipient conversion to rapamycin increases potentially tolerogenic immune cells. Kidney International. 85: 743-5. PMID 24682122 DOI: 10.1038/Ki.2013.420  0.46
2014 Rosborough BR, Mathews LR, Matta BM, Liu Q, Raïch-Regué D, Thomson AW, Turnquist HR. Cutting edge: Flt3 ligand mediates STAT3-independent expansion but STAT3-dependent activation of myeloid-derived suppressor cells. Journal of Immunology (Baltimore, Md. : 1950). 192: 3470-3. PMID 24639346 DOI: 10.4049/Jimmunol.1300058  0.597
2014 Huang H, Nace GW, McDonald KA, Tai S, Klune JR, Rosborough BR, Ding Q, Loughran P, Zhu X, Beer-Stolz D, Chang EB, Billiar T, Tsung A. Hepatocyte-specific high-mobility group box 1 deletion worsens the injury in liver ischemia/reperfusion: a role for intracellular high-mobility group box 1 in cellular protection. Hepatology (Baltimore, Md.). 59: 1984-97. PMID 24375466 DOI: 10.1002/Hep.26976  0.301
2014 Stenger EO, Rosborough BR, Mathews LR, Ma H, Mapara MY, Thomson AW, Turnquist HR. IL-12hi rapamycin-conditioned dendritic cells mediate IFN-γ-dependent apoptosis of alloreactive CD4+ T cells in vitro and reduce lethal graft-versus-host disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 20: 192-201. PMID 24239650 DOI: 10.1016/J.Bbmt.2013.11.007  0.68
2014 Rosborough BR, Raïch-Regué D, Turnquist HR, Thomson AW. Regulatory myeloid cells in transplantation. Transplantation. 97: 367-79. PMID 24092382 DOI: 10.1097/Tp.0B013E3182A860De  0.543
2014 Matta B, Rosborough B, Mathews L, Liu Q, Raich-Regue D, Thomson A, Turnquist H. Myeloid-Specific STAT3 Deletion Augments Flt3 Ligand-Driven Myeloid-Derived Suppressor Cell Expansion But Limits Their Suppressor Function. Transplantation. 98: 293. DOI: 10.1097/00007890-201407151-00917  0.519
2014 Matta B, Lott J, Mathews L, Rosborough B, Blazar B, Turnquist H. IL-33 Promotes Selective Expansion of ST2+Foxp3+ Regulatory T Cells Dependent On Dendritic Cell Secretion of IL-2. Transplantation. 98: 291. DOI: 10.1097/00007890-201407151-00909  0.547
2014 Raich-Regue D, Rosborough B, Turnquist H, Thomson A. Myeloid Dendritic Cell-Specific mTORC2 Deficiency Enhances Alloreactive Th1 and Th17 Cell Responses and Skin Graft Rejection. Transplantation. 98: 18-19. DOI: 10.1097/00007890-201407151-00052  0.538
2014 Stenger E, Rosborough B, Mathews L, Ma HH, Mapara MY, Thomson AW, Turnquist H. IL-12hi Rapamycin-Conditioned Dendritic Cells Mediate IFN-γ-Dependent and Fas-Supported Apoptosis of Alloreactive CD4+ T Cells and Inhibit Graft-Versus-Host Disease Biology of Blood and Marrow Transplantation. 20: S281-S283. DOI: 10.1016/J.Bbmt.2013.12.474  0.647
2013 Huang H, Chen HW, Evankovich J, Yan W, Rosborough BR, Nace GW, Ding Q, Loughran P, Beer-Stolz D, Billiar TR, Esmon CT, Tsung A. Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury. Journal of Immunology (Baltimore, Md. : 1950). 191: 2665-79. PMID 23904166 DOI: 10.4049/Jimmunol.1202733  0.327
2013 Nace GW, Huang H, Klune JR, Eid RE, Rosborough BR, Korff S, Li S, Shapiro RA, Stolz DB, Sodhi CP, Hackam DJ, Geller DA, Billiar TR, Tsung A. Cellular-specific role of toll-like receptor 4 in hepatic ischemia-reperfusion injury in mice. Hepatology (Baltimore, Md.). 58: 374-87. PMID 23460269 DOI: 10.1002/Hep.26346  0.365
2013 Rosborough BR, Raïch-Regué D, Matta BM, Lee K, Gan B, DePinho RA, Hackstein H, Boothby M, Turnquist HR, Thomson AW. Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction. Blood. 121: 3619-30. PMID 23444404 DOI: 10.1182/Blood-2012-08-448290  0.653
2013 Corbitt N, Kimura S, Isse K, Specht S, Chedwick L, Rosborough BR, Lunz JG, Murase N, Yokota S, Demetris AJ. Gut bacteria drive Kupffer cell expansion via MAMP-mediated ICAM-1 induction on sinusoidal endothelium and influence preservation-reperfusion injury after orthotopic liver transplantation. The American Journal of Pathology. 182: 180-91. PMID 23159949 DOI: 10.1016/J.Ajpath.2012.09.010  0.344
2012 Matta BM, Raimondi G, Rosborough BR, Sumpter TL, Thomson AW. IL-27 production and STAT3-dependent upregulation of B7-H1 mediate immune regulatory functions of liver plasmacytoid dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 5227-37. PMID 22508931 DOI: 10.4049/Jimmunol.1103382  0.626
2012 Zhang L, Cardinal JS, Pan P, Rosborough BR, Chang Y, Yan W, Huang H, Billiar TR, Rosengart MR, Tsung A. Splenocyte apoptosis and autophagy is mediated by interferon regulatory factor 1 during murine endotoxemia. Shock (Augusta, Ga.). 37: 511-7. PMID 22266972 DOI: 10.1097/Shk.0B013E318249Cfa2  0.419
2012 Rosborough BR, Castellaneta A, Natarajan S, Thomson AW, Turnquist HR. Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo. Journal of Leukocyte Biology. 91: 701-9. PMID 22028329 DOI: 10.1189/Jlb.0311119  0.614
2012 Stenger EO, Rosborough BR, Mathews L, Ma H, Mapara M, Thomson AW, Turnquist HR. IL-12hi Rapamycin-Conditioned Dendritic Cells Mediate IFN-γ-Dependent Apoptosis of Alloreactive CD4+ T Cells and Limit Graft-Versus-Host Diseas Blood. 120: 4110-4110. DOI: 10.1182/Blood.V120.21.4110.4110  0.628
2012 Matta BM, Raimondi G, Rosborough BR, Thomson A. IL-27 and B7-H1 Mediate Liver Plasmacytoid DC Ability to Regulate Alloreactive T Cell Responses and Suppress Delayed-Type Hypersensitivity Transplantation Journal. 94: 308. DOI: 10.1097/00007890-201211271-00571  0.618
2012 Rosborough BR, Matta BM, Turnquist HR, Thomson A. Concomitant Inhibition of mTORC1 and mTORC2 in Dendritic Cells Reduces SOCS3 Expression Resulting in Enhanced Immunoregulatory PD-L1 Expression and IL-10 Secretion Transplantation Journal. 94: 13. DOI: 10.1097/00007890-201211271-00023  0.542
2012 Stenger E, Rosborough B, Mathews L, Ma H, Mapara M, Thomson A, Turnquist H. IL-12hi Rapamycin-Conditioned Dendritic Cells Induce Apoptosis of Alloreactive CD4+ T Cells in an Ifn-γ-Dependent Manner and Inhibit Graft-Versus-Host Disease Biology of Blood and Marrow Transplantation. 18: S361. DOI: 10.1016/J.Bbmt.2011.12.418  0.647
2011 Turnquist HR, Zhao Z, Rosborough BR, Liu Q, Castellaneta A, Isse K, Wang Z, Lang M, Stolz DB, Zheng XX, Demetris AJ, Liew FY, Wood KJ, Thomson AW. IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival. Journal of Immunology (Baltimore, Md. : 1950). 187: 4598-610. PMID 21949025 DOI: 10.4049/Jimmunol.1100519  0.653
2010 Turnquist HR, Cardinal J, Macedo C, Rosborough BR, Sumpter TL, Geller DA, Metes D, Thomson AW. mTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS. Blood. 115: 4758-69. PMID 20335217 DOI: 10.1182/Blood-2009-10-251488  0.641
2010 Castillo-Rama M, Macedo C, Rosborough BR, Turnquist HR, Metes D, Thomson AW. RAPAMYCIN-CONDITIONED HUMAN DENDRITIC CELLS EXHIBIT INCREASED IL-12P70 PRODUCTION UPON EXPOSURE TO PRO-INFLAMMATORY CYTOKINES Transplantation Journal. 90: 519. DOI: 10.1097/00007890-201007272-00967  0.569
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