Peter Veng-Pedersen - Publications

Affiliations: 
Pharmacy University of Iowa, Iowa City, IA 
Area:
Pharmacy, Cell Biology

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 D'Cunha R, Schmidt R, Widness JA, Mock DM, Yan X, Cress GA, Kuruvilla D, Veng-Pedersen P, An G. Target-mediated disposition population pharmacokinetics model of erythropoietin in premature neonates following multiple intravenous and subcutaneous dosing regimens. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105013. PMID 31340188 DOI: 10.1016/J.Ejps.2019.105013  0.36
2018 Mock DM, Nalbant D, Kyosseva SV, Schmidt RL, An G, Matthews NI, Vlaar APJ, van Bruggen R, de Korte D, Strauss RG, Cancelas JA, Franco RS, Veng-Pedersen P, Widness JA. Development, validation, and potential applications of biotinylated red blood cells for posttransfusion kinetics and other physiological studies: evidenced-based analysis and recommendations. Transfusion. PMID 29770455 DOI: 10.1111/Trf.14647  0.328
2017 An G, Ohls RK, Christensen RD, Widness JA, Mock DM, Veng-Pedersen P. Population Pharmacokinetics of Darbepoetin in Infants Following Single Intravenous and Subcutaneous Dosing. Journal of Pharmaceutical Sciences. PMID 28189627 DOI: 10.1016/J.Xphs.2017.02.001  0.345
2016 An G, Widness JA, Mock DM, Veng-Pedersen P. A Novel Physiology-Based Mathematical Model to Estimate Red Blood Cell Lifespan in Different Human Age Groups. The Aaps Journal. PMID 27215601 DOI: 10.1208/S12248-016-9923-0  0.327
2016 Shrestha RP, Horowitz J, Hollot CV, Germain MJ, Widness JA, Mock DM, Veng-Pedersen P, Chait Y. Models for the red blood cell lifespan. Journal of Pharmacokinetics and Pharmacodynamics. PMID 27039311 DOI: 10.1007/S10928-016-9470-4  0.324
2015 Kuruvilla DJ, Widness JA, Nalbant D, Schmidt RL, Mock DM, Veng-Pedersen P. A Mass Balance-Based Semiparametric Approach to Evaluate Neonatal Erythropoiesis. The Aaps Journal. PMID 26502725 DOI: 10.1208/S12248-015-9831-8  0.336
2015 Kuruvilla DJ, Widness JA, Nalbant D, Schmidt RL, Mock DM, Veng-Pedersen P. A Method to Evaluate Fetal Erythropoiesis from Postnatal Survival of Fetal RBCs. The Aaps Journal. PMID 26017162 DOI: 10.1208/S12248-015-9784-Y  0.335
2015 Kulshrestha M, Sola-Visner M, Widness JA, Veng-Pedersen P, Mager DE. Mathematical model of platelet turnover in thrombocytopenic and nonthrombocytopenic preterm neonates. American Journal of Physiology. Heart and Circulatory Physiology. 308: H68-73. PMID 25362135 DOI: 10.1152/Ajpheart.00528.2013  0.352
2014 Rosebraugh MR, Widness JA, Nalbant D, Cress G, Veng-Pedersen P. Pharmacodynamically optimized erythropoietin treatment combined with phlebotomy reduction predicted to eliminate blood transfusions in selected preterm infants. Pediatric Research. 75: 336-42. PMID 24216541 DOI: 10.1038/Pr.2013.213  0.761
2013 Saleh MI, Nalbant D, Widness JA, Veng-Pedersen P. Population pharmacodynamic analysis of erythropoiesis in preterm infants for determining the anemia treatment potential of erythropoietin. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 304: R772-81. PMID 23485870 DOI: 10.1152/Ajpregu.00173.2012  0.367
2013 Rosebraugh MR, Widness JA, Nalbant D, Veng-Pedersen P. A mathematical modeling approach to quantify the role of phlebotomy losses and need for transfusions in neonatal anemia. Transfusion. 53: 1353-60. PMID 23033916 DOI: 10.1111/J.1537-2995.2012.03908.X  0.763
2012 Kania-Korwel I, Barnhart CD, Stamou M, Truong KM, El-Komy MH, Lein PJ, Veng-Pedersen P, Lehmler HJ. 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) and its hydroxylated metabolites are enantiomerically enriched in female mice. Environmental Science & Technology. 46: 11393-401. PMID 22974126 DOI: 10.1021/Es302810T  0.755
2012 Rosebraugh MR, Widness JA, Veng-Pedersen P. Multidose optimization simulation of erythropoietin treatment in preterm infants. Pediatric Research. 71: 332-7. PMID 22391632 DOI: 10.1038/Pr.2011.75  0.76
2012 Mock DM, Matthews NI, Zhu S, Strauss RG, Schmidt RL, Zimmerman MB, Nalbant D, Freise KJ, Saleh M, Veng-Pedersen P, Widness JA. Comparison of red blood cell survival in sheep determined using red blood cells labeled with either biotin at multiple densities or [14C]cyanate: validation of a model to study human physiology and disease. Transfusion. 52: 963-73. PMID 22229348 DOI: 10.1111/J.1537-2995.2011.03512.X  0.661
2011 Lin CW, Warram JH, Veng-Pedersen P. A Bayesian population analysis of the development of type 2 diabetes in the offspring of diabetic parents. Journal of Pharmacokinetics and Pharmacodynamics. 38: 563-79. PMID 21833670 DOI: 10.1007/S10928-011-9208-2  0.618
2011 El-Komy MH, Schmidt RL, Widness JA, Veng-Pedersen P. Differential pharmacokinetic analysis of in vivo erythropoietin receptor interaction with erythropoietin and continuous erythropoietin receptor activator in sheep. Biopharmaceutics & Drug Disposition. 32: 276-88. PMID 21678432 DOI: 10.1002/Bdd.757  0.772
2011 Rosebraugh M, Widness JA, Veng-Pedersen P. Receptor-based dosing optimization of erythropoietin in juvenile sheep after phlebotomy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1214-20. PMID 21460232 DOI: 10.1124/Dmd.110.036855  0.771
2011 Saleh MI, Widness JA, Veng-Pedersen P. Pharmacodynamic analysis of stress erythropoiesis: change in erythropoietin receptor pool size following double phlebotomies in sheep. Biopharmaceutics & Drug Disposition. 32: 131-9. PMID 21456051 DOI: 10.1002/Bdd.743  0.355
2011 El-Komy MH, Widness JA, Veng-Pedersen P. Pharmacokinetic analysis of continuous erythropoietin receptor activator disposition in adult sheep using a target-mediated, physiologic recirculation model and a tracer interaction methodology. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 603-9. PMID 21209249 DOI: 10.1124/Dmd.110.036236  0.779
2010 Osei-Bimpong A, Saleh M, Sola-Visner M, Widness J, Veng-Pedersen P. Correction for effect of cold storage on immature platelet fraction. Journal of Clinical Laboratory Analysis. 24: 431-3. PMID 21089177 DOI: 10.1002/Jcla.20426  0.303
2010 Xie L, Hoffman RP, Veng-Pedersen P. Population analysis of ethnicity and first-phase insulin release. Diabetes Research and Clinical Practice. 89: 243-9. PMID 20570007 DOI: 10.1016/J.Diabres.2010.04.025  0.741
2010 Mock DM, Matthews NI, Zhu S, Burmeister LF, Zimmerman MB, Strauss RG, Schmidt RL, Nalbant D, Freise KJ, Veng-Pedersen P, Widness JA. Red blood cell (RBC) volume can be independently determined in vivo in the sheep using ovine RBCs labeled at different densities of biotin. Transfusion. 50: 2553-64. PMID 20561297 DOI: 10.1111/J.1537-2995.2010.02744.X  0.661
2010 Kania-Korwel I, El-Komy MH, Veng-Pedersen P, Lehmler HJ. Clearance of polychlorinated biphenyl atropisomers is enantioselective in female C57Bl/6 mice. Environmental Science & Technology. 44: 2828-35. PMID 20384376 DOI: 10.1021/Es901781P  0.762
2010 Nalbant D, Saleh M, Goldman FD, Widness JA, Veng-Pedersen P. Evidence of receptor-mediated elimination of erythropoietin by analysis of erythropoietin receptor mRNA expression in bone marrow and erythropoietin clearance during anemia. The Journal of Pharmacology and Experimental Therapeutics. 333: 528-32. PMID 20103588 DOI: 10.1124/Jpet.109.163568  0.321
2010 Freise KJ, Widness JA, Veng-Pedersen P. Erythropoietic response to endogenous erythropoietin in premature very low birth weight infants. The Journal of Pharmacology and Experimental Therapeutics. 332: 229-37. PMID 19808699 DOI: 10.1124/Jpet.109.159905  0.685
2009 Lin CW, Veng-Pedersen P. Analysis of PK/PD risk factors for development of type 2 diabetes in high risk population using Bayesian analysis of glucose-insulin kinetics. Journal of Pharmacokinetics and Pharmacodynamics. 36: 421-41. PMID 19756980 DOI: 10.1007/S10928-009-9130-Z  0.605
2009 Neelakantan S, Widness JA, Schmidt RL, Veng-Pedersen P. Erythropoietin pharmacokinetic/pharmacodynamic analysis suggests higher doses in treating neonatal anemia. Pediatrics International : Official Journal of the Japan Pediatric Society. 51: 25-32. PMID 19371274 DOI: 10.1111/J.1442-200X.2008.02648.X  0.731
2009 Xie L, Hoffman RP, Veng-Pedersen P. Noncompartmental pharmacokinetics analysis of glucose-stimulated insulin response in African-American and Caucasian youths. Biopharmaceutics & Drug Disposition. 30: 117-25. PMID 19288584 DOI: 10.1002/Bdd.652  0.741
2009 Freise KJ, Schmidt RL, Gingerich EL, Veng-Pedersen P, Widness JA. The effect of anticoagulant, storage temperature and dilution on cord blood hematology parameters over time. International Journal of Laboratory Hematology. 31: 496-504. PMID 18422712 DOI: 10.1111/J.1751-553X.2008.01066.X  0.649
2008 Freise KJ, Schmidt RL, Widness JA, Veng-Pedersen P. Pharmacodynamic modeling of the effect of changes in the environment on cellular lifespan and cellular response. Journal of Pharmacokinetics and Pharmacodynamics. 35: 527-52. PMID 18937059 DOI: 10.1007/S10928-008-9100-X  0.675
2008 Veng-Pedersen P, Freise KJ, Schmidt RL, Widness JA. Pharmacokinetic differentiation of drug candidates using system analysis and physiological-based modelling. Comparison of C.E.R.A. and erythropoietin. The Journal of Pharmacy and Pharmacology. 60: 1321-34. PMID 18812025 DOI: 10.1211/Jpp/60.10.0008  0.662
2008 Freise KJ, Widness JA, Schmidt RL, Veng-Pedersen P. Modeling time variant distributions of cellular lifespans: increases in circulating reticulocyte lifespans following double phlebotomies in sheep. Journal of Pharmacokinetics and Pharmacodynamics. 35: 285-323. PMID 18553126 DOI: 10.1007/S10928-008-9089-1  0.669
2007 Freise KJ, Widness JA, Schmidt RL, Veng-Pedersen P. Pharmacodynamic analysis of time-variant cellular disposition: reticulocyte disposition changes in phlebotomized sheep. Journal of Pharmacokinetics and Pharmacodynamics. 34: 519-47. PMID 17516153 DOI: 10.1007/S10928-007-9056-2  0.676
2007 Freise KJ, Widness JA, Segar JL, Schmidt RL, Veng-Pedersen P. Increased erythropoietin elimination in fetal sheep following chronic phlebotomy. Pharmaceutical Research. 24: 1653-9. PMID 17457660 DOI: 10.1007/S11095-007-9295-3  0.651
2007 Widness JA, Schmidt RL, Hohl RJ, Goldman FD, Al-Huniti NH, Freise KJ, Veng-Pedersen P. Change in erythropoietin pharmacokinetics following hematopoietic transplantation Clinical Pharmacology and Therapeutics. 81: 873-879. PMID 17429351 DOI: 10.1038/Sj.Clpt.6100165  0.734
2007 Gupta N, Al-Huniti NH, Veng-Pedersen P. Individualized pharmacokinetic risk assessment for development of diabetes in high risk population. Diabetes Research and Clinical Practice. 78: 93-101. PMID 17368857 DOI: 10.1016/J.Diabres.2007.02.013  0.614
2006 Warwood TL, Ohls RK, Lambert DK, Leve EA, Veng-Pedersen P, Christensen RD. Urinary excretion of darbepoetin after intravenous vs subcutaneous administration to preterm neonates. Journal of Perinatology. 26: 636-639. PMID 16929342 DOI: 10.1038/Sj.Jp.7211596  0.302
2006 Neelakantan S, Widness JA, Schmidt RL, Veng-Pedersen P. A 'bottom-up' approach for endo-PK/PD analysis. Biopharmaceutics & Drug Disposition. 27: 313-27. PMID 16892181 DOI: 10.1002/Bdd.508  0.733
2006 Warwood TL, Ohls RK, Lambert DK, Jones C, Scoffield SH, Gupta N, Veng-Pedersen P, Christensen RD. Intravenous administration of darbepoetin to NICU patients. Journal of Perinatology. 26: 296-300. PMID 16554846 DOI: 10.1038/Sj.Jp.7211498  0.325
2006 Durairaj L, Neelakantan S, Launspach J, Watt JL, Allaman MM, Kearney WR, Veng-Pedersen P, Zabner J. Bronchoscopic assessment of airway retention time of aerosolized xylitol. Respiratory Research. 7: 27. PMID 16483382 DOI: 10.1186/1465-9921-7-27  0.708
2005 Al-Huniti NH, Widness JA, Schmidt RL, Veng-Pedersen P. Pharmacodynamic analysis of changes in reticulocyte subtype distribution in phlebotomy-induced stress erythropoiesis. Journal of Pharmacokinetics and Pharmacodynamics. 32: 359-76. PMID 16284920 DOI: 10.1007/S10928-005-0009-3  0.637
2005 Neelakantan S, Veng-Pedersen P. Determination of drug absorption rate in time-variant disposition by direct deconvolution using beta clearance correction and end-constrained non-parametric regression. Biopharmaceutics & Drug Disposition. 26: 353-70. PMID 16088968 DOI: 10.1002/Bdd.468  0.712
2004 Al-Huniti NH, Widness JA, Schmidt RL, Veng-Pedersen P. Erythropoietin production rate in phlebotomy-induced acute anemia. Biopharmaceutics & Drug Disposition. 25: 389-97. PMID 15529399 DOI: 10.1002/Bdd.424  0.624
2004 Bechensteen AG, Chapel S, Veng-Pedersen P, Widness JA. Posttransfusion recovery of stored red blood cells in very low birth weight infants using a hemoglobin balance model. Transfusion. 44: 1019-24. PMID 15225242 DOI: 10.1111/J.1537-2995.2004.03376.X  0.666
2004 Veng-Pedersen P, Chapel S, Al-Huniti NH, Schimdt RL, Sedars EM, Hohl RJ, Widness JA. Pharmacokinetic tracer kinetics analysis of changes in erythropoietin receptor population in phylebotomy-induced anemia and bone marrow ablation Biopharmaceutics and Drug Disposition. 25: 149-156. PMID 15108217 DOI: 10.1002/bdd.395  0.761
2004 Al-Huniti NH, Widness JA, Schmidt RL, Veng-Pedersen P. Pharmacokinetic/pharmacodynamic analysis of paradoxal regulation of erythropoietin production in acute anemia. The Journal of Pharmacology and Experimental Therapeutics. 310: 202-8. PMID 14988424 DOI: 10.1124/Jpet.104.066027  0.678
2003 Veng-Pedersen P, Chapel S, Al-Huniti NH, Schmidt RL, Sedars EM, Hohl RJ, Widness JA. A differential pharmacokinetic analysis of the erythropoietin receptor population in newborn and adult sheep Journal of Pharmacology and Experimental Therapeutics. 306: 532-537. PMID 12750427 DOI: 10.1124/Jpet.103.052431  0.758
2001 Chapel S, Veng-Pedersen P, Hohl RJ, Schmidt RL, Mcguire EM, Widness JA. Changes in erythropoietin pharmacokinetics following busulfan-induced bone marrow ablation in sheep: Evidence for bone marrow as a major erythropoietin elimination pathway Journal of Pharmacology and Experimental Therapeutics. 298: 820-824. PMID 11454947  0.663
2001 Veng-Pedersen P. Noncompartmentally-based pharmacokinetic modeling Advanced Drug Delivery Reviews. 48: 265-300. PMID 11369086 DOI: 10.1016/S0169-409X(01)00119-3  0.313
2001 Chapel SH, Veng-Pedersen P, Schmidt RL, Widness JA. Receptor-based model accounts for phlebotomy-induced changes in erythropoietin pharmacokinetics. Experimental Hematology. 29: 425-31. PMID 11301182 DOI: 10.1016/S0301-472X(01)00614-2  0.718
2000 Veng-Pedersen P, Gobburu JV, Meyer MC, Straughn AB. Carbamazepine level-A in vivo-in vitro correlation (IVIVC): a scaled convolution based predictive approach. Biopharmaceutics & Drug Disposition. 21: 1-6. PMID 11038432 DOI: 10.1002/1099-081X(200001)21:1<1::Aid-Bdd207>3.0.Co;2-D  0.322
2000 Chapel SH, Veng-Pedersen P, Schmidt RL, Widness JA. A pharmacodynamic analysis of erythropoietin-stimulated reticulocyte response in phlebotomized sheep. The Journal of Pharmacology and Experimental Therapeutics. 295: 346-51. PMID 10992000  0.684
1999 Veng-Pedersen P, Widness JA, Pereira LM, Schmidt RL, Lowe LS. A comparison of nonlinear pharmacokinetics of erythropoietin in sheep and humans. Biopharmaceutics & Drug Disposition. 20: 217-23. PMID 10440797 DOI: 10.1002/(Sici)1099-081X(199905)20:4<217::Aid-Bdd177>3.0.Co;2-6  0.336
1998 Veng-Pedersen P, Widness JA, Wang J, Schmidt RL. A tracer interaction method for nonlinear pharmacokinetics analysis: application to evaluation of nonlinear elimination. Journal of Pharmacokinetics and Biopharmaceutics. 25: 569-93. PMID 9679223 DOI: 10.1023/A:1025765330455  0.3
1994 Veng-Pedersen P, Modi NB. Application of a Variable Direction Hysteresis minimization Approach in Describing the Central Nervous System Pharmacodynamic Effects of Alfentanil in Rabbits Journal of Pharmaceutical Sciences. 83: 351-356. PMID 8207680 DOI: 10.1002/Jps.2600830317  0.331
1993 Veng-Pedersen P, Modi NB. A System Approach to Pharmacodynamics. Input-Effect Control System Analysis of Central Nervous System Effect of Alfentanil Journal of Pharmaceutical Sciences. 82: 266-272. PMID 8450420 DOI: 10.1002/Jps.2600820310  0.337
1993 Veng-Pedersen P, Modi NB, Widness JA, Pereira LM, Schmidt RL, Georgieff MK. A system approach to pharmacodynamics. Plasma iron mobilization by endogenous erythropoietin in the sheep fetus; Evidence of threshold response in spontaneous hypoxemia Journal of Pharmaceutical Sciences. 82: 804-807. PMID 8377118 DOI: 10.1002/Jps.2600820810  0.362
1992 Kling PJ, Widness JA, Guillery EN, Veng-Pedersen P, Peters C, deAlarcon PA. Pharmacokinetics and pharmacodynamics of erythropoietin during therapy in an infant with renal failure The Journal of Pediatrics. 121: 822-825. PMID 1432439 DOI: 10.1016/S0022-3476(05)81923-7  0.304
1991 Veng-Pedersen P. Stochastic Interpretation of Linear Pharmacokinetics: A Linear System Analysis Approach Journal of Pharmaceutical Sciences. 80: 621-631. PMID 1941557 DOI: 10.1002/Jps.2600800703  0.3
1991 Mandema JW, Veng-Pedersen P, Danhof M. Estimation of amobarbital plasma-effect site equilibration kinetics. Relevance of polyexponential conductance functions. Journal of Pharmacokinetics and Biopharmaceutics. 19: 617-634. PMID 1815044 DOI: 10.1007/Bf01080870  0.314
1990 Furst DE, Herman RA, Koehnke R, Ericksen N, Hash L, Riggs CE, Porras A, Veng-Pedersen P. Effect of aspirin and sulindac on methotrexate clearance. Journal of Pharmaceutical Sciences. 79: 782-6. PMID 2273459 DOI: 10.1002/Jps.2600790907  0.306
1989 Brashear RE, Veng-Pedersen P, Karol MD. Pharmacokinetics of theophylline before and after nephrectomy in dogs Biopharmaceutics & Drug Disposition. 10: 87-99. PMID 2923964 DOI: 10.1002/Bdd.2510100110  0.342
1987 Veng-Pedersen P, Gillespie WR. Theorems and implications of a model-independent elimination/distribution function decomposition of linear and some nonlinear drug dispositions. III. Peripheral bioavailability and distribution time concepts applied to the evaluation of distribution kinetics. Journal of Pharmacokinetics and Biopharmaceutics. 15: 281-304. PMID 3668805 DOI: 10.1007/Bf01066323  0.31
1984 Veng-Pedersen P. Theorems and implications of a model independent elimination/distribution function decomposition of linear and some nonlinear drug dispositions. I. Derivations and theoretical analysis Journal of Pharmacokinetics and Biopharmaceutics. 12: 627-648. PMID 6533297 DOI: 10.1007/Bf01059557  0.308
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