Year |
Citation |
Score |
2019 |
D'Cunha R, Schmidt R, Widness JA, Mock DM, Yan X, Cress GA, Kuruvilla D, Veng-Pedersen P, An G. Target-mediated disposition population pharmacokinetics model of erythropoietin in premature neonates following multiple intravenous and subcutaneous dosing regimens. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105013. PMID 31340188 DOI: 10.1016/J.Ejps.2019.105013 |
0.36 |
|
2018 |
Mock DM, Nalbant D, Kyosseva SV, Schmidt RL, An G, Matthews NI, Vlaar APJ, van Bruggen R, de Korte D, Strauss RG, Cancelas JA, Franco RS, Veng-Pedersen P, Widness JA. Development, validation, and potential applications of biotinylated red blood cells for posttransfusion kinetics and other physiological studies: evidenced-based analysis and recommendations. Transfusion. PMID 29770455 DOI: 10.1111/Trf.14647 |
0.328 |
|
2017 |
An G, Ohls RK, Christensen RD, Widness JA, Mock DM, Veng-Pedersen P. Population Pharmacokinetics of Darbepoetin in Infants Following Single Intravenous and Subcutaneous Dosing. Journal of Pharmaceutical Sciences. PMID 28189627 DOI: 10.1016/J.Xphs.2017.02.001 |
0.345 |
|
2016 |
An G, Widness JA, Mock DM, Veng-Pedersen P. A Novel Physiology-Based Mathematical Model to Estimate Red Blood Cell Lifespan in Different Human Age Groups. The Aaps Journal. PMID 27215601 DOI: 10.1208/S12248-016-9923-0 |
0.327 |
|
2016 |
Shrestha RP, Horowitz J, Hollot CV, Germain MJ, Widness JA, Mock DM, Veng-Pedersen P, Chait Y. Models for the red blood cell lifespan. Journal of Pharmacokinetics and Pharmacodynamics. PMID 27039311 DOI: 10.1007/S10928-016-9470-4 |
0.324 |
|
2015 |
Kuruvilla DJ, Widness JA, Nalbant D, Schmidt RL, Mock DM, Veng-Pedersen P. A Mass Balance-Based Semiparametric Approach to Evaluate Neonatal Erythropoiesis. The Aaps Journal. PMID 26502725 DOI: 10.1208/S12248-015-9831-8 |
0.336 |
|
2015 |
Kuruvilla DJ, Widness JA, Nalbant D, Schmidt RL, Mock DM, Veng-Pedersen P. A Method to Evaluate Fetal Erythropoiesis from Postnatal Survival of Fetal RBCs. The Aaps Journal. PMID 26017162 DOI: 10.1208/S12248-015-9784-Y |
0.335 |
|
2015 |
Kulshrestha M, Sola-Visner M, Widness JA, Veng-Pedersen P, Mager DE. Mathematical model of platelet turnover in thrombocytopenic and nonthrombocytopenic preterm neonates. American Journal of Physiology. Heart and Circulatory Physiology. 308: H68-73. PMID 25362135 DOI: 10.1152/Ajpheart.00528.2013 |
0.352 |
|
2014 |
Rosebraugh MR, Widness JA, Nalbant D, Cress G, Veng-Pedersen P. Pharmacodynamically optimized erythropoietin treatment combined with phlebotomy reduction predicted to eliminate blood transfusions in selected preterm infants. Pediatric Research. 75: 336-42. PMID 24216541 DOI: 10.1038/Pr.2013.213 |
0.761 |
|
2013 |
Saleh MI, Nalbant D, Widness JA, Veng-Pedersen P. Population pharmacodynamic analysis of erythropoiesis in preterm infants for determining the anemia treatment potential of erythropoietin. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 304: R772-81. PMID 23485870 DOI: 10.1152/Ajpregu.00173.2012 |
0.367 |
|
2013 |
Rosebraugh MR, Widness JA, Nalbant D, Veng-Pedersen P. A mathematical modeling approach to quantify the role of phlebotomy losses and need for transfusions in neonatal anemia. Transfusion. 53: 1353-60. PMID 23033916 DOI: 10.1111/J.1537-2995.2012.03908.X |
0.763 |
|
2012 |
Kania-Korwel I, Barnhart CD, Stamou M, Truong KM, El-Komy MH, Lein PJ, Veng-Pedersen P, Lehmler HJ. 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) and its hydroxylated metabolites are enantiomerically enriched in female mice. Environmental Science & Technology. 46: 11393-401. PMID 22974126 DOI: 10.1021/Es302810T |
0.755 |
|
2012 |
Rosebraugh MR, Widness JA, Veng-Pedersen P. Multidose optimization simulation of erythropoietin treatment in preterm infants. Pediatric Research. 71: 332-7. PMID 22391632 DOI: 10.1038/Pr.2011.75 |
0.76 |
|
2012 |
Mock DM, Matthews NI, Zhu S, Strauss RG, Schmidt RL, Zimmerman MB, Nalbant D, Freise KJ, Saleh M, Veng-Pedersen P, Widness JA. Comparison of red blood cell survival in sheep determined using red blood cells labeled with either biotin at multiple densities or [14C]cyanate: validation of a model to study human physiology and disease. Transfusion. 52: 963-73. PMID 22229348 DOI: 10.1111/J.1537-2995.2011.03512.X |
0.661 |
|
2011 |
Lin CW, Warram JH, Veng-Pedersen P. A Bayesian population analysis of the development of type 2 diabetes in the offspring of diabetic parents. Journal of Pharmacokinetics and Pharmacodynamics. 38: 563-79. PMID 21833670 DOI: 10.1007/S10928-011-9208-2 |
0.618 |
|
2011 |
El-Komy MH, Schmidt RL, Widness JA, Veng-Pedersen P. Differential pharmacokinetic analysis of in vivo erythropoietin receptor interaction with erythropoietin and continuous erythropoietin receptor activator in sheep. Biopharmaceutics & Drug Disposition. 32: 276-88. PMID 21678432 DOI: 10.1002/Bdd.757 |
0.772 |
|
2011 |
Rosebraugh M, Widness JA, Veng-Pedersen P. Receptor-based dosing optimization of erythropoietin in juvenile sheep after phlebotomy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1214-20. PMID 21460232 DOI: 10.1124/Dmd.110.036855 |
0.771 |
|
2011 |
Saleh MI, Widness JA, Veng-Pedersen P. Pharmacodynamic analysis of stress erythropoiesis: change in erythropoietin receptor pool size following double phlebotomies in sheep. Biopharmaceutics & Drug Disposition. 32: 131-9. PMID 21456051 DOI: 10.1002/Bdd.743 |
0.355 |
|
2011 |
El-Komy MH, Widness JA, Veng-Pedersen P. Pharmacokinetic analysis of continuous erythropoietin receptor activator disposition in adult sheep using a target-mediated, physiologic recirculation model and a tracer interaction methodology. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 603-9. PMID 21209249 DOI: 10.1124/Dmd.110.036236 |
0.779 |
|
2010 |
Osei-Bimpong A, Saleh M, Sola-Visner M, Widness J, Veng-Pedersen P. Correction for effect of cold storage on immature platelet fraction. Journal of Clinical Laboratory Analysis. 24: 431-3. PMID 21089177 DOI: 10.1002/Jcla.20426 |
0.303 |
|
2010 |
Xie L, Hoffman RP, Veng-Pedersen P. Population analysis of ethnicity and first-phase insulin release. Diabetes Research and Clinical Practice. 89: 243-9. PMID 20570007 DOI: 10.1016/J.Diabres.2010.04.025 |
0.741 |
|
2010 |
Mock DM, Matthews NI, Zhu S, Burmeister LF, Zimmerman MB, Strauss RG, Schmidt RL, Nalbant D, Freise KJ, Veng-Pedersen P, Widness JA. Red blood cell (RBC) volume can be independently determined in vivo in the sheep using ovine RBCs labeled at different densities of biotin. Transfusion. 50: 2553-64. PMID 20561297 DOI: 10.1111/J.1537-2995.2010.02744.X |
0.661 |
|
2010 |
Kania-Korwel I, El-Komy MH, Veng-Pedersen P, Lehmler HJ. Clearance of polychlorinated biphenyl atropisomers is enantioselective in female C57Bl/6 mice. Environmental Science & Technology. 44: 2828-35. PMID 20384376 DOI: 10.1021/Es901781P |
0.762 |
|
2010 |
Nalbant D, Saleh M, Goldman FD, Widness JA, Veng-Pedersen P. Evidence of receptor-mediated elimination of erythropoietin by analysis of erythropoietin receptor mRNA expression in bone marrow and erythropoietin clearance during anemia. The Journal of Pharmacology and Experimental Therapeutics. 333: 528-32. PMID 20103588 DOI: 10.1124/Jpet.109.163568 |
0.321 |
|
2010 |
Freise KJ, Widness JA, Veng-Pedersen P. Erythropoietic response to endogenous erythropoietin in premature very low birth weight infants. The Journal of Pharmacology and Experimental Therapeutics. 332: 229-37. PMID 19808699 DOI: 10.1124/Jpet.109.159905 |
0.685 |
|
2009 |
Lin CW, Veng-Pedersen P. Analysis of PK/PD risk factors for development of type 2 diabetes in high risk population using Bayesian analysis of glucose-insulin kinetics. Journal of Pharmacokinetics and Pharmacodynamics. 36: 421-41. PMID 19756980 DOI: 10.1007/S10928-009-9130-Z |
0.605 |
|
2009 |
Neelakantan S, Widness JA, Schmidt RL, Veng-Pedersen P. Erythropoietin pharmacokinetic/pharmacodynamic analysis suggests higher doses in treating neonatal anemia. Pediatrics International : Official Journal of the Japan Pediatric Society. 51: 25-32. PMID 19371274 DOI: 10.1111/J.1442-200X.2008.02648.X |
0.731 |
|
2009 |
Xie L, Hoffman RP, Veng-Pedersen P. Noncompartmental pharmacokinetics analysis of glucose-stimulated insulin response in African-American and Caucasian youths. Biopharmaceutics & Drug Disposition. 30: 117-25. PMID 19288584 DOI: 10.1002/Bdd.652 |
0.741 |
|
2009 |
Freise KJ, Schmidt RL, Gingerich EL, Veng-Pedersen P, Widness JA. The effect of anticoagulant, storage temperature and dilution on cord blood hematology parameters over time. International Journal of Laboratory Hematology. 31: 496-504. PMID 18422712 DOI: 10.1111/J.1751-553X.2008.01066.X |
0.649 |
|
2008 |
Freise KJ, Schmidt RL, Widness JA, Veng-Pedersen P. Pharmacodynamic modeling of the effect of changes in the environment on cellular lifespan and cellular response. Journal of Pharmacokinetics and Pharmacodynamics. 35: 527-52. PMID 18937059 DOI: 10.1007/S10928-008-9100-X |
0.675 |
|
2008 |
Veng-Pedersen P, Freise KJ, Schmidt RL, Widness JA. Pharmacokinetic differentiation of drug candidates using system analysis and physiological-based modelling. Comparison of C.E.R.A. and erythropoietin. The Journal of Pharmacy and Pharmacology. 60: 1321-34. PMID 18812025 DOI: 10.1211/Jpp/60.10.0008 |
0.662 |
|
2008 |
Freise KJ, Widness JA, Schmidt RL, Veng-Pedersen P. Modeling time variant distributions of cellular lifespans: increases in circulating reticulocyte lifespans following double phlebotomies in sheep. Journal of Pharmacokinetics and Pharmacodynamics. 35: 285-323. PMID 18553126 DOI: 10.1007/S10928-008-9089-1 |
0.669 |
|
2007 |
Freise KJ, Widness JA, Schmidt RL, Veng-Pedersen P. Pharmacodynamic analysis of time-variant cellular disposition: reticulocyte disposition changes in phlebotomized sheep. Journal of Pharmacokinetics and Pharmacodynamics. 34: 519-47. PMID 17516153 DOI: 10.1007/S10928-007-9056-2 |
0.676 |
|
2007 |
Freise KJ, Widness JA, Segar JL, Schmidt RL, Veng-Pedersen P. Increased erythropoietin elimination in fetal sheep following chronic phlebotomy. Pharmaceutical Research. 24: 1653-9. PMID 17457660 DOI: 10.1007/S11095-007-9295-3 |
0.651 |
|
2007 |
Widness JA, Schmidt RL, Hohl RJ, Goldman FD, Al-Huniti NH, Freise KJ, Veng-Pedersen P. Change in erythropoietin pharmacokinetics following hematopoietic transplantation Clinical Pharmacology and Therapeutics. 81: 873-879. PMID 17429351 DOI: 10.1038/Sj.Clpt.6100165 |
0.734 |
|
2007 |
Gupta N, Al-Huniti NH, Veng-Pedersen P. Individualized pharmacokinetic risk assessment for development of diabetes in high risk population. Diabetes Research and Clinical Practice. 78: 93-101. PMID 17368857 DOI: 10.1016/J.Diabres.2007.02.013 |
0.614 |
|
2006 |
Warwood TL, Ohls RK, Lambert DK, Leve EA, Veng-Pedersen P, Christensen RD. Urinary excretion of darbepoetin after intravenous vs subcutaneous administration to preterm neonates. Journal of Perinatology. 26: 636-639. PMID 16929342 DOI: 10.1038/Sj.Jp.7211596 |
0.302 |
|
2006 |
Neelakantan S, Widness JA, Schmidt RL, Veng-Pedersen P. A 'bottom-up' approach for endo-PK/PD analysis. Biopharmaceutics & Drug Disposition. 27: 313-27. PMID 16892181 DOI: 10.1002/Bdd.508 |
0.733 |
|
2006 |
Warwood TL, Ohls RK, Lambert DK, Jones C, Scoffield SH, Gupta N, Veng-Pedersen P, Christensen RD. Intravenous administration of darbepoetin to NICU patients. Journal of Perinatology. 26: 296-300. PMID 16554846 DOI: 10.1038/Sj.Jp.7211498 |
0.325 |
|
2006 |
Durairaj L, Neelakantan S, Launspach J, Watt JL, Allaman MM, Kearney WR, Veng-Pedersen P, Zabner J. Bronchoscopic assessment of airway retention time of aerosolized xylitol. Respiratory Research. 7: 27. PMID 16483382 DOI: 10.1186/1465-9921-7-27 |
0.708 |
|
2005 |
Al-Huniti NH, Widness JA, Schmidt RL, Veng-Pedersen P. Pharmacodynamic analysis of changes in reticulocyte subtype distribution in phlebotomy-induced stress erythropoiesis. Journal of Pharmacokinetics and Pharmacodynamics. 32: 359-76. PMID 16284920 DOI: 10.1007/S10928-005-0009-3 |
0.637 |
|
2005 |
Neelakantan S, Veng-Pedersen P. Determination of drug absorption rate in time-variant disposition by direct deconvolution using beta clearance correction and end-constrained non-parametric regression. Biopharmaceutics & Drug Disposition. 26: 353-70. PMID 16088968 DOI: 10.1002/Bdd.468 |
0.712 |
|
2004 |
Al-Huniti NH, Widness JA, Schmidt RL, Veng-Pedersen P. Erythropoietin production rate in phlebotomy-induced acute anemia. Biopharmaceutics & Drug Disposition. 25: 389-97. PMID 15529399 DOI: 10.1002/Bdd.424 |
0.624 |
|
2004 |
Bechensteen AG, Chapel S, Veng-Pedersen P, Widness JA. Posttransfusion recovery of stored red blood cells in very low birth weight infants using a hemoglobin balance model. Transfusion. 44: 1019-24. PMID 15225242 DOI: 10.1111/J.1537-2995.2004.03376.X |
0.666 |
|
2004 |
Veng-Pedersen P, Chapel S, Al-Huniti NH, Schimdt RL, Sedars EM, Hohl RJ, Widness JA. Pharmacokinetic tracer kinetics analysis of changes in erythropoietin receptor population in phylebotomy-induced anemia and bone marrow ablation Biopharmaceutics and Drug Disposition. 25: 149-156. PMID 15108217 DOI: 10.1002/bdd.395 |
0.761 |
|
2004 |
Al-Huniti NH, Widness JA, Schmidt RL, Veng-Pedersen P. Pharmacokinetic/pharmacodynamic analysis of paradoxal regulation of erythropoietin production in acute anemia. The Journal of Pharmacology and Experimental Therapeutics. 310: 202-8. PMID 14988424 DOI: 10.1124/Jpet.104.066027 |
0.678 |
|
2003 |
Veng-Pedersen P, Chapel S, Al-Huniti NH, Schmidt RL, Sedars EM, Hohl RJ, Widness JA. A differential pharmacokinetic analysis of the erythropoietin receptor population in newborn and adult sheep Journal of Pharmacology and Experimental Therapeutics. 306: 532-537. PMID 12750427 DOI: 10.1124/Jpet.103.052431 |
0.758 |
|
2001 |
Chapel S, Veng-Pedersen P, Hohl RJ, Schmidt RL, Mcguire EM, Widness JA. Changes in erythropoietin pharmacokinetics following busulfan-induced bone marrow ablation in sheep: Evidence for bone marrow as a major erythropoietin elimination pathway Journal of Pharmacology and Experimental Therapeutics. 298: 820-824. PMID 11454947 |
0.663 |
|
2001 |
Veng-Pedersen P. Noncompartmentally-based pharmacokinetic modeling Advanced Drug Delivery Reviews. 48: 265-300. PMID 11369086 DOI: 10.1016/S0169-409X(01)00119-3 |
0.313 |
|
2001 |
Chapel SH, Veng-Pedersen P, Schmidt RL, Widness JA. Receptor-based model accounts for phlebotomy-induced changes in erythropoietin pharmacokinetics. Experimental Hematology. 29: 425-31. PMID 11301182 DOI: 10.1016/S0301-472X(01)00614-2 |
0.718 |
|
2000 |
Veng-Pedersen P, Gobburu JV, Meyer MC, Straughn AB. Carbamazepine level-A in vivo-in vitro correlation (IVIVC): a scaled convolution based predictive approach. Biopharmaceutics & Drug Disposition. 21: 1-6. PMID 11038432 DOI: 10.1002/1099-081X(200001)21:1<1::Aid-Bdd207>3.0.Co;2-D |
0.322 |
|
2000 |
Chapel SH, Veng-Pedersen P, Schmidt RL, Widness JA. A pharmacodynamic analysis of erythropoietin-stimulated reticulocyte response in phlebotomized sheep. The Journal of Pharmacology and Experimental Therapeutics. 295: 346-51. PMID 10992000 |
0.684 |
|
1999 |
Veng-Pedersen P, Widness JA, Pereira LM, Schmidt RL, Lowe LS. A comparison of nonlinear pharmacokinetics of erythropoietin in sheep and humans. Biopharmaceutics & Drug Disposition. 20: 217-23. PMID 10440797 DOI: 10.1002/(Sici)1099-081X(199905)20:4<217::Aid-Bdd177>3.0.Co;2-6 |
0.336 |
|
1998 |
Veng-Pedersen P, Widness JA, Wang J, Schmidt RL. A tracer interaction method for nonlinear pharmacokinetics analysis: application to evaluation of nonlinear elimination. Journal of Pharmacokinetics and Biopharmaceutics. 25: 569-93. PMID 9679223 DOI: 10.1023/A:1025765330455 |
0.3 |
|
1994 |
Veng-Pedersen P, Modi NB. Application of a Variable Direction Hysteresis minimization Approach in Describing the Central Nervous System Pharmacodynamic Effects of Alfentanil in Rabbits Journal of Pharmaceutical Sciences. 83: 351-356. PMID 8207680 DOI: 10.1002/Jps.2600830317 |
0.331 |
|
1993 |
Veng-Pedersen P, Modi NB. A System Approach to Pharmacodynamics. Input-Effect Control System Analysis of Central Nervous System Effect of Alfentanil Journal of Pharmaceutical Sciences. 82: 266-272. PMID 8450420 DOI: 10.1002/Jps.2600820310 |
0.337 |
|
1993 |
Veng-Pedersen P, Modi NB, Widness JA, Pereira LM, Schmidt RL, Georgieff MK. A system approach to pharmacodynamics. Plasma iron mobilization by endogenous erythropoietin in the sheep fetus; Evidence of threshold response in spontaneous hypoxemia Journal of Pharmaceutical Sciences. 82: 804-807. PMID 8377118 DOI: 10.1002/Jps.2600820810 |
0.362 |
|
1992 |
Kling PJ, Widness JA, Guillery EN, Veng-Pedersen P, Peters C, deAlarcon PA. Pharmacokinetics and pharmacodynamics of erythropoietin during therapy in an infant with renal failure The Journal of Pediatrics. 121: 822-825. PMID 1432439 DOI: 10.1016/S0022-3476(05)81923-7 |
0.304 |
|
1991 |
Veng-Pedersen P. Stochastic Interpretation of Linear Pharmacokinetics: A Linear System Analysis Approach Journal of Pharmaceutical Sciences. 80: 621-631. PMID 1941557 DOI: 10.1002/Jps.2600800703 |
0.3 |
|
1991 |
Mandema JW, Veng-Pedersen P, Danhof M. Estimation of amobarbital plasma-effect site equilibration kinetics. Relevance of polyexponential conductance functions. Journal of Pharmacokinetics and Biopharmaceutics. 19: 617-634. PMID 1815044 DOI: 10.1007/Bf01080870 |
0.314 |
|
1990 |
Furst DE, Herman RA, Koehnke R, Ericksen N, Hash L, Riggs CE, Porras A, Veng-Pedersen P. Effect of aspirin and sulindac on methotrexate clearance. Journal of Pharmaceutical Sciences. 79: 782-6. PMID 2273459 DOI: 10.1002/Jps.2600790907 |
0.306 |
|
1989 |
Brashear RE, Veng-Pedersen P, Karol MD. Pharmacokinetics of theophylline before and after nephrectomy in dogs Biopharmaceutics & Drug Disposition. 10: 87-99. PMID 2923964 DOI: 10.1002/Bdd.2510100110 |
0.342 |
|
1987 |
Veng-Pedersen P, Gillespie WR. Theorems and implications of a model-independent elimination/distribution function decomposition of linear and some nonlinear drug dispositions. III. Peripheral bioavailability and distribution time concepts applied to the evaluation of distribution kinetics. Journal of Pharmacokinetics and Biopharmaceutics. 15: 281-304. PMID 3668805 DOI: 10.1007/Bf01066323 |
0.31 |
|
1984 |
Veng-Pedersen P. Theorems and implications of a model independent elimination/distribution function decomposition of linear and some nonlinear drug dispositions. I. Derivations and theoretical analysis Journal of Pharmacokinetics and Biopharmaceutics. 12: 627-648. PMID 6533297 DOI: 10.1007/Bf01059557 |
0.308 |
|
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