Year |
Citation |
Score |
2023 |
Winz C, Zong WX, Suh N. Endocrine-disrupting compounds and metabolomic reprogramming in breast cancer. Journal of Biochemical and Molecular Toxicology. e23506. PMID 37598318 DOI: 10.1002/jbt.23506 |
0.344 |
|
2023 |
Xie T, Zahid H, Ali AR, Joyce R, Yang G, Winz C, Le Y, Zhou R, Furmanski P, Hu L, Suh N. Inhibitors of Keap1-Nrf2 protein-protein interaction reduce estrogen responsive gene expression and oxidative stress in estrogen receptor-positive breast cancer. Toxicology and Applied Pharmacology. 116375. PMID 36634873 DOI: 10.1016/j.taap.2023.116375 |
0.335 |
|
2021 |
Winz C, Suh N. Understanding the Mechanistic Link between Bisphenol A and Cancer Stem Cells: A Cancer Prevention Perspective. Journal of Cancer Prevention. 26: 18-24. PMID 33842402 DOI: 10.15430/JCP.2021.26.1.18 |
0.311 |
|
2021 |
Shan NL, Shin Y, Yang G, Furmanski P, Suh N. Breast cancer stem cells: A review of their characteristics and the agents that affect them. Molecular Carcinogenesis. PMID 33428807 DOI: 10.1002/mc.23277 |
0.35 |
|
2020 |
Shan NL, Minden A, Furmanski P, Bak MJ, Cai L, Wernyj R, Sargsyan D, Cheng D, Wu R, Kuo HD, Li SN, Fang M, Maehr H, Kong AN, Suh N. Analysis of the Transcriptome: Regulation of Cancer Stemness in Breast Ductal Carcinoma In Situ by Vitamin D Compounds. Cancer Prevention Research (Philadelphia, Pa.). PMID 32467291 DOI: 10.1158/1940-6207.Capr-19-0566 |
0.483 |
|
2020 |
Yang CS, Luo P, Zeng Z, Wang H, Malafa M, Suh N. Vitamin E and cancer prevention: Studies with different forms of tocopherols and tocotrienols. Molecular Carcinogenesis. PMID 32017273 DOI: 10.1002/Mc.23160 |
0.394 |
|
2019 |
Liu F, Zhou J, Kundu-Roy T, Wahler J, So JY, Lin Y, Lou Y, Barnard NJ, Matsuura I, Suh N. Abstract 1073: Role of CD44 in the transition of ductal carcinomain situto invasive breast carcinoma Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-1073 |
0.713 |
|
2019 |
Shan NL, Bak MJ, Cai L, Wernyj R, Sargsyan D, Cheng D, Minden A, Kong AT, Suh N. Abstract 5067: Identification of key drivers of cancer stemness and progression regulated by vitamin D compounds in ductal carcinomain situbreast cancer Cancer Research. 79: 5067-5067. DOI: 10.1158/1538-7445.Am2019-5067 |
0.49 |
|
2018 |
Bak MJ, Furmanski P, Shan NL, Lee HJ, Bao C, Lin Y, Shih WJ, Yang CS, Suh N. Tocopherols inhibit estrogen-induced cancer stemness and OCT4 signaling in breast cancer. Carcinogenesis. PMID 29846560 DOI: 10.1093/Carcin/Bgy071 |
0.506 |
|
2018 |
Shan NL, Yang J, Bak MJ, Wahler J, Suh N. Abstract 276: Targeting cancer stem cells with chemopreventive agents for breast cancer prevention Cancer Research. 78: 276-276. DOI: 10.1158/1538-7445.Am2018-276 |
0.507 |
|
2018 |
Bao C, Kramata P, Lee HJ, Suh N. Back Cover: Regulation of Hedgehog Signaling in Cancer by Natural and Dietary Compounds Molecular Nutrition & Food Research. 62: 1870015. DOI: 10.1002/Mnfr.201870015 |
0.36 |
|
2017 |
Bao C, Kramata P, Lee HJ, Suh N. Regulation of Hedgehog Signaling in Cancer by Natural and Dietary Compounds. Molecular Nutrition & Food Research. PMID 29164817 DOI: 10.1002/Mnfr.201700621 |
0.385 |
|
2017 |
Das Gupta S, Patel M, Wahler J, Bak MJ, Wall BA, Lee MJ, Lin Y, Shih WJ, Cai L, Yang CS, Suh N. Differential gene regulation and tumor inhibitory activities of alpha-, delta- and gamma-tocopherols in estrogen-mediated mammary carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). PMID 28972008 DOI: 10.1158/1940-6207.Capr-17-0190 |
0.409 |
|
2017 |
Bak MJ, Das Gupta S, Wahler J, Lee HJ, Li X, Lee MJ, Yang CS, Suh N. Inhibitory effects of γ- and δ-tocopherols on estrogen-stimulated breast cancer in vitro and in vivo. Cancer Prevention Research (Philadelphia, Pa.). PMID 28096236 DOI: 10.1158/1940-6207.Capr-16-0223 |
0.523 |
|
2017 |
Yang CS, Chen J, Liu AB, Lee M, Wang H, Li G, Zhang L, Reuhl K, Suh N. Abstract 1255: PhIP/DSS-induced colon carcinogenesis in CYP1A-humanized mice and its prevention by tocopherols Cancer Research. 77: 1255-1255. DOI: 10.1158/1538-7445.Am2017-1255 |
0.306 |
|
2016 |
Shan NL, Wahler J, Lee HJ, Bak MJ, Gupta SD, Maehr H, Suh N. Vitamin D compounds inhibit cancer stem-like cells and induce differentiation in triple negative breast cancer. The Journal of Steroid Biochemistry and Molecular Biology. PMID 27923595 DOI: 10.1016/J.Jsbmb.2016.12.001 |
0.524 |
|
2016 |
Belorusova AY, Suh N, Lee HJ, So JY, Maehr H, Rochel N. Structural analysis and biological activities of BXL0124, a gemini analog of vitamin D. The Journal of Steroid Biochemistry and Molecular Biology. PMID 27650654 DOI: 10.1016/J.Jsbmb.2016.09.015 |
0.761 |
|
2016 |
Liu Z, Kundu-Roy T, Matsuura I, Wang G, Lin Y, Lou YR, Barnard NJ, Wang XF, Huang MT, Suh N, Liu F. Carcinogen 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis is accelerated in Smad3 heterozygous mice compared to Smad3 wild type mice. Oncotarget. PMID 27588495 DOI: 10.18632/Oncotarget.11713 |
0.442 |
|
2016 |
Chen JX, Liu A, Lee MJ, Wang H, Yu S, Chi E, Reuhl K, Suh N, Yang CS. δ- and γ-tocopherols inhibit phIP/DSS-induced colon carcinogenesis by protection against early cellular and DNA damages. Molecular Carcinogenesis. PMID 27175800 DOI: 10.1002/Mc.22481 |
0.411 |
|
2016 |
Bak MJ, Gupta SD, Wahler J, Suh N. Role of dietary bioactive natural products in estrogen receptor-positive breast cancer. Seminars in Cancer Biology. PMID 27016037 DOI: 10.1016/J.Semcancer.2016.03.001 |
0.446 |
|
2016 |
Heo TH, Wahler J, Suh N. Potential therapeutic implications of IL-6/IL-6R/gp130-targeting agents in breast cancer. Oncotarget. 7: 15460-73. PMID 26840088 DOI: 10.18632/Oncotarget.7102 |
0.344 |
|
2016 |
Gupta SD, Suh N. Tocopherols in cancer: An update. Molecular Nutrition & Food Research. PMID 26751721 DOI: 10.1002/Mnfr.201500847 |
0.392 |
|
2016 |
Bak MJ, Gupta SD, Wahler J, Lee M, Lin Y, Shih WJ, Yang CS, Suh N. Abstract 5237: Protection of tocopherols against estrogen-induced breast cancer via mechanisms targeting cancer stem cells Cancer Research. 76: 5237-5237. DOI: 10.1158/1538-7445.Am2016-5237 |
0.538 |
|
2016 |
Gupta SD, Wahler J, Bak MJ, Lee M, Lin Y, Shih WJ, Yang CS, Suh N. Abstract 5235: Dietary administration of δ- and γ-tocopherol inhibits estrogen-mediated mammary tumorigenesis in ACI rats Cancer Research. 76: 5235-5235. DOI: 10.1158/1538-7445.Am2016-5235 |
0.386 |
|
2016 |
Liu Z, Kundu TR, Matsuura I, Wang G, Lin Y, Lou Y, Barnard NJ, Wang X, Huang M, Suh N, Liu F. Abstract 4070: Carcinogen 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis is accelerated in Smad3 heterozygous mice compared to Smad3 wild type mice Cancer Research. 76: 4070-4070. DOI: 10.1158/1538-7445.Am2016-4070 |
0.449 |
|
2015 |
Chen JX, Li G, Wang H, Liu A, Lee MJ, Reuhl K, Suh N, Bosland MC, Yang CS. Dietary tocopherols inhibit PhIP-induced prostate carcinogenesis in CYP1A-humanized mice. Cancer Letters. PMID 26582657 DOI: 10.1016/J.Canlet.2015.11.010 |
0.358 |
|
2015 |
Wahler J, Suh N. Targeting HER2 Positive Breast Cancer with Chemopreventive Agents. Current Pharmacology Reports. 1: 324-335. PMID 26442201 DOI: 10.1007/S40495-015-0040-Z |
0.438 |
|
2015 |
Das Gupta S, Sae-Tan S, Wahler J, So JY, Bak MJ, Cheng LC, Lee MJ, Lin Y, Shih WJ, Shull JD, Safe S, Yang CS, Suh N. Dietary γ-Tocopherol Rich Mixture Inhibits Estrogen-Induced Mammary Tumorigenesis by Modulating Estrogen Metabolism, Antioxidant Response and PPARγ. Cancer Prevention Research (Philadelphia, Pa.). PMID 26130252 DOI: 10.1158/1940-6207.Capr-15-0154 |
0.784 |
|
2015 |
So JY, Wahler J, Das Gupta S, Salerno DM, Maehr H, Uskokovic M, Suh N. HES1-mediated inhibition of Notch1 signaling by a Gemini vitamin D analog leads to decreased CD44(+)/CD24(-/low) tumor-initiating subpopulation in basal-like breast cancer. The Journal of Steroid Biochemistry and Molecular Biology. 148: 111-21. PMID 25541438 DOI: 10.1016/J.Jsbmb.2014.12.013 |
0.789 |
|
2015 |
So JY, Suh N. Targeting cancer stem cells in solid tumors by vitamin D. The Journal of Steroid Biochemistry and Molecular Biology. 148: 79-85. PMID 25460302 DOI: 10.1016/J.Jsbmb.2014.10.007 |
0.776 |
|
2015 |
Wahler J, So JY, Cheng LC, Maehr H, Uskokovic M, Suh N. Vitamin D compounds reduce mammosphere formation and decrease expression of putative stem cell markers in breast cancer. The Journal of Steroid Biochemistry and Molecular Biology. 148: 148-55. PMID 25445919 DOI: 10.1016/J.Jsbmb.2014.10.016 |
0.794 |
|
2015 |
Yang CS, Chen JX, Liu AB, Wang H, Lee M, Yu S, Zhao C, Kuo Y, Chi E, Suh N. Abstract 2814: Inhibition of PhIP/DSS-induced colon carcinogenesis by different forms of tocopherols in CYP1A-humanized mice Cancer Research. 75: 2814-2814. DOI: 10.1158/1538-7445.Am2015-2814 |
0.324 |
|
2015 |
Gupta SD, Sae-tan S, Wahler J, So JY, Cheng LC, Bak MJ, Lee M, Lin Y, Shih WJ, Yang CS, Suh N. Abstract 2797: Dietary administration of a γ-tocopherol rich mixture of tocopherols inhibits estrogen-mediated mammary tumorigenesis Cancer Research. 75: 2797-2797. DOI: 10.1158/1538-7445.Am2015-2797 |
0.739 |
|
2015 |
Wahler J, Cheng LC, Maehr H, Uskokovic M, Suh N. Abstract 1912: Reduction of microRNA-21 by vitamin D compounds during ductal carcinoma in situ transition to invasive ductal carcinoma Cancer Research. 75: 1912-1912. DOI: 10.1158/1538-7445.Am2015-1912 |
0.353 |
|
2014 |
So JY, Lin JJ, Wahler J, Liby KT, Sporn MB, Suh N. A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer. Plos One. 9: e107616. PMID 25229616 DOI: 10.1371/Journal.Pone.0107616 |
0.78 |
|
2014 |
Das Gupta S, So JY, Wall B, Wahler J, Smolarek AK, Sae-Tan S, Soewono KY, Yu H, Lee MJ, Thomas PE, Yang CS, Suh N. Tocopherols inhibit oxidative and nitrosative stress in estrogen-induced early mammary hyperplasia in ACI rats. Molecular Carcinogenesis. PMID 24782330 DOI: 10.1002/Mc.22164 |
0.803 |
|
2014 |
Wahler J, So JY, Kim YC, Liu F, Maehr H, Uskokovic M, Suh N. Inhibition of the transition of ductal carcinoma in situ to invasive ductal carcinoma by a Gemini vitamin D analog. Cancer Prevention Research (Philadelphia, Pa.). 7: 617-26. PMID 24691501 DOI: 10.1158/1940-6207.Capr-13-0362 |
0.783 |
|
2014 |
Gupta SD, So JY, Wahler J, Lee M, Yang CS, Suh N. Abstract 243: Tocopherols inhibit oxidative and nitrosative stress in estrogen-induced early mammary hyperplasia in ACI rats Cancer Research. 74: 243-243. DOI: 10.1158/1538-7445.Am2014-243 |
0.752 |
|
2014 |
So JY, Salerno DM, Maehr H, Uskokovic M, Suh N. Abstract 1248: The Gemini vitamin D analogue BXL0124 inhibits Notch signaling via HES1, resulting in the reduction of CD44+/CD24-/low subpopulation and proliferation of MCF10DCIS cells Cancer Research. 74: 1248-1248. DOI: 10.1158/1538-7445.Am2014-1248 |
0.774 |
|
2014 |
Wahler J, Maehr H, Uskokovic M, Suh N. Abstract 1236: A gemini vitamin D analogue, BXL0124, represses mammosphere formation and decreases expression of stem cell markers in MCF10DCIS breast cancer cells Cancer Research. 74: 1236-1236. DOI: 10.1158/1538-7445.Am2014-1236 |
0.535 |
|
2013 |
So JY, Wahler JE, Yoon T, Smolarek AK, Lin Y, Shih WJ, Maehr H, Uskokovic M, Liby KT, Sporn MB, Suh N. Oral administration of a gemini vitamin D analog, a synthetic triterpenoid and the combination prevents mammary tumorigenesis driven by ErbB2 overexpression. Cancer Prevention Research (Philadelphia, Pa.). 6: 959-70. PMID 23856074 DOI: 10.1158/1940-6207.Capr-13-0087 |
0.83 |
|
2013 |
Maehr H, Rochel N, Lee HJ, Suh N, Uskokovic MR. Diastereotopic and deuterium effects in gemini. Journal of Medicinal Chemistry. 56: 3878-88. PMID 23566225 DOI: 10.1021/Jm400032T |
0.364 |
|
2013 |
Su ZY, Khor TO, Shu L, Lee JH, Saw CL, Wu TY, Huang Y, Suh N, Yang CS, Conney AH, Wu Q, Kong AN. Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 cells by natural phytochemicals Z-ligustilide and Radix angelica sinensis via promoter CpG demethylation. Chemical Research in Toxicology. 26: 477-85. PMID 23441843 DOI: 10.1021/Tx300524P |
0.32 |
|
2013 |
So JY, Smolarek AK, Salerno DM, Maehr H, Uskokovic M, Liu F, Suh N. Targeting CD44-STAT3 Signaling by Gemini Vitamin D Analog Leads to Inhibition of Invasion in Basal-Like Breast Cancer Plos One. 8. PMID 23326564 DOI: 10.1371/Journal.Pone.0054020 |
0.821 |
|
2013 |
Yang CS, Suh N. Cancer prevention by different forms of tocopherols Topics in Current Chemistry. 329: 21-34. PMID 22836899 DOI: 10.1007/128_2012_345 |
0.336 |
|
2013 |
Smolarek AK, So JY, Thomas PE, Lee HJ, Paul S, Dombrowski A, Wang CX, Saw CL, Khor TO, Kong AN, Reuhl K, Lee MJ, Yang CS, Suh N. Dietary tocopherols inhibit cell proliferation, regulate expression of ERα, PPARγ, and Nrf2, and decrease serum inflammatory markers during the development of mammary hyperplasia. Molecular Carcinogenesis. 52: 514-25. PMID 22389237 DOI: 10.1002/Mc.21886 |
0.811 |
|
2013 |
Mazumdar A, Uray I, Litzenburger B, Zhang Y, Hill J, Suh N, Brown P. Abstract ED05-01: Targeting nuclear hormone receptors for breast cancer prevention Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-Ed05-01 |
0.44 |
|
2013 |
Yang CS, Suh N, Stoner G, Dong Z, Surh Y. Allan H. Conney: In Memoriam (1930-2013) Cancer Prevention Research. 6: 1376-1377. DOI: 10.1158/1940-6207.Capr-13-0368 |
0.308 |
|
2013 |
Liu F, Roy T, So JY, Smolarek A, Lu Y, Suh N. Abstract 780: Knockdown of p53 increases tumorigenicity of human breast cancer cells. Cancer Research. 73: 780-780. DOI: 10.1158/1538-7445.Am2013-780 |
0.818 |
|
2013 |
Wahler J, So JY, Smolarek A, Maehr H, Uskokovic M, Suh N. Abstract 184: A gemini vVitamin D analog, BXL0124, inhibits mammary tumorigenesis by delaying the transition of ductal carcinoma in situ to iInvasive breast carcinoma. Cancer Research. 73: 184-184. DOI: 10.1158/1538-7445.Am2013-184 |
0.827 |
|
2013 |
So JY, Smolarek AK, Maehr H, Uskokovic M, Liby K, Sporn MB, Suh N. Abstract 180: Inhibition of tumorigenesis by a novel Gemini vitamin D analog BXL0124 and a synthetic triterpenoid CDDO-Im in MMTV-HER2/neu transgenic mice. Cancer Research. 73: 180-180. DOI: 10.1158/1538-7445.Am2013-180 |
0.837 |
|
2012 |
So JY, Lee HJ, Kramata P, Minden A, Suh N. Differential Expression of Key Signaling Proteins in MCF10 Cell Lines, a Human Breast Cancer Progression Model. Molecular and Cellular Pharmacology. 4: 31-40. PMID 24558516 DOI: 11.4255/mcpharmacol.12.03 |
0.759 |
|
2012 |
Smolarek AK, So JY, Burgess B, Kong AN, Reuhl K, Lin Y, Shih WJ, Li G, Lee MJ, Chen YK, Yang CS, Suh N. Dietary administration of δ- and γ-tocopherol inhibits tumorigenesis in the animal model of estrogen receptor-positive, but not HER-2 breast cancer. Cancer Prevention Research (Philadelphia, Pa.). 5: 1310-20. PMID 22964476 DOI: 10.1158/1940-6207.Capr-12-0263 |
0.827 |
|
2012 |
Yang CS, Suh N, Kong AN. Does vitamin E prevent or promote cancer? Cancer Prevention Research (Philadelphia, Pa.). 5: 701-5. PMID 22490437 DOI: 10.1158/1940-6207.Capr-12-0045 |
0.446 |
|
2012 |
Huang Y, Khor TO, Shu L, Saw CL, Wu TY, Suh N, Yang CS, Kong AN. A γ-tocopherol-rich mixture of tocopherols maintains Nrf2 expression in prostate tumors of TRAMP mice via epigenetic inhibition of CpG methylation. The Journal of Nutrition. 142: 818-23. PMID 22457388 DOI: 10.3945/Jn.111.153114 |
0.355 |
|
2012 |
Suh N, Paul S, Lee HJ, Yoon T, Shah N, Son AI, Reddi AH, Medici D, Sporn MB. Synthetic triterpenoids, CDDO-Imidazolide and CDDO-Ethyl amide, induce chondrogenesis. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 20: 446-50. PMID 22343171 DOI: 10.1016/J.Joca.2012.01.018 |
0.736 |
|
2012 |
Suh N, Pezzuto JM. Strawberry fields forever? Cancer Prevention Research (Philadelphia, Pa.). 5: 30-3. PMID 22219164 DOI: 10.1158/1940-6207.Capr-11-0534 |
0.352 |
|
2012 |
Suh N. Abstract CN08-04: Novel Gemini vitamin D compounds for prevention of breast cancer by targeting stem cells Cancer Prevention Research. 5: CN08-04-CN08-04. DOI: 10.1158/1940-6207.Prev-12-Cn08-04 |
0.563 |
|
2012 |
Mazumdar A, Zhang Y, Hill J, Suh N, Brown P. Abstract A62: Combination of BXL-0124, a vitamin D analog and LG100268 for the prevention of ER-negative breast cancer Cancer Prevention Research. 5: A62-A62. DOI: 10.1158/1940-6207.PREV-12-A62 |
0.337 |
|
2012 |
Li G, Chen Y, Wang H, Liu AB, Chen CX, Guo X, Zheng X, Suh N, Yang CS. Abstract A40: Inhibition of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced prostate and colon carcinogenesis in hCYP1A mice by tocopherols Cancer Prevention Research. 5: A40-A40. DOI: 10.1158/1940-6207.Prev-12-A40 |
0.351 |
|
2012 |
So JY, Smolarek AK, Shah N, Maehr H, Uskokovic M, Liu F, Suh N. Abstract 929: Repression of CD44 is a key molecular action of a novel Gemini vitamin D BXL0124 to inhibit breast cancer cell invasion induced by HGF/Met signaling Cancer Research. 72: 929-929. DOI: 10.1158/1538-7445.Am2012-929 |
0.83 |
|
2011 |
Smolarek AK, Suh N. Chemopreventive activity of vitamin e in breast cancer: A focus on γ- and δ-tocopherol Nutrients. 3: 962-986. PMID 22254089 DOI: 10.3390/Nu3110962 |
0.801 |
|
2011 |
Huet T, Maehr H, Lee HJ, Uskokovic MR, Suh N, Moras D, Rochel N. Structure-function study of gemini derivatives with two different side chains at C-20, Gemini-0072 and Gemini-0097. Medchemcomm. 2: 424-429. PMID 22180837 DOI: 10.1039/C1Md00059D |
0.323 |
|
2011 |
Suh N, Reddy BS, DeCastro A, Paul S, Lee HJ, Smolarek AK, So JY, Simi B, Wang CX, Janakiram NB, Steele V, Rao CV. Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/β-catenin/cyclin D1 signaling pathway in rats. Cancer Prevention Research (Philadelphia, Pa.). 4: 1895-902. PMID 21764859 DOI: 10.1158/1940-6207.Capr-11-0222 |
0.803 |
|
2011 |
So JY, Lee HJ, Smolarek AK, Paul S, Wang CX, Maehr H, Uskokovic M, Zheng X, Conney AH, Cai L, Liu F, Suh N. A novel Gemini vitamin D analog represses the expression of a stem cell marker CD44 in breast cancer. Molecular Pharmacology. 79: 360-7. PMID 21115634 DOI: 10.1124/Mol.110.068403 |
0.823 |
|
2011 |
So JY, Smolarek AK, Maehr H, Uskokovic M, Cai L, Liu F, Suh N. Abstract 839: A novel Gemini vitamin D analog represses a stem cell marker CD44 and its variant CD44v6 and inhibits CD44-Met signaling in breast cancer Cancer Research. 71: 839-839. DOI: 10.1158/1538-7445.Am2011-839 |
0.834 |
|
2011 |
Suh N, Reddy BS, Paul S, DeCastro A, Lee HJ, Smolarek AK, So JY, Simi B, Wang CX, Janakiram NB, Steele VE, Rao CV. Abstract 833: Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/beta-catenin/cyclin D1 signaling pathway in rats Cancer Research. 71: 833-833. DOI: 10.1158/1538-7445.Am2011-833 |
0.804 |
|
2011 |
Smolarek AK, So JY, Thomas PE, Lee HJ, Paul S, Dombrowski A, Wang C, Kong AT, Reuhl K, Lee M, Yang CS, Suh N. Abstract 1851: Dietary mixed tocopherols inhibit cell proliferation in mammary hyperplasia, suppress the expression of inflammatory markers, and upregulate PPARγ Cancer Research. 71: 1851-1851. DOI: 10.1158/1538-7445.Am2011-1851 |
0.789 |
|
2010 |
Mizuno CS, Paul S, Suh N, Rimando AM. Synthesis and biological evaluation of retinoid-chalcones as inhibitors of colon cancer cell growth. Bioorganic & Medicinal Chemistry Letters. 20: 7385-7. PMID 21041085 DOI: 10.1016/J.Bmcl.2010.10.038 |
0.758 |
|
2010 |
Paul S, Mizuno CS, Lee HJ, Zheng X, Chajkowisk S, Rimoldi JM, Conney A, Suh N, Rimando AM. In vitro and in vivo studies on stilbene analogs as potential treatment agents for colon cancer. European Journal of Medicinal Chemistry. 45: 3702-8. PMID 20627379 DOI: 10.1016/J.Ejmech.2010.05.019 |
0.797 |
|
2010 |
Lee HJ, So JY, DeCastro A, Smolarek A, Paul S, Maehr H, Uskokovic M, Suh N. Gemini vitamin D analog suppresses ErbB2-positive mammary tumor growth via inhibition of ErbB2/AKT/ERK signaling. The Journal of Steroid Biochemistry and Molecular Biology. 121: 408-12. PMID 20304052 DOI: 10.1016/J.Jsbmb.2010.03.053 |
0.812 |
|
2010 |
Paul S, DeCastro AJ, Lee HJ, Smolarek AK, So JY, Simi B, Wang CX, Zhou R, Rimando AM, Suh N. Dietary intake of pterostilbene, a constituent of blueberries, inhibits the beta-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats. Carcinogenesis. 31: 1272-8. PMID 20061362 DOI: 10.1093/Carcin/Bgq004 |
0.805 |
|
2010 |
Ju J, Picinich SC, Yang Z, Zhao Y, Suh N, Kong AN, Yang CS. Cancer-preventive activities of tocopherols and tocotrienols. Carcinogenesis. 31: 533-42. PMID 19748925 DOI: 10.1093/Carcin/Bgp205 |
0.463 |
|
2010 |
So JY, Lee HJ, Smolarek AK, Paul S, Maehr H, Uskokovic M, Cai L, Liu F, Suh N. Abstract 644: A novel Gemini vitamin D analogue represses the expression of a stem cell marker CD44 in breast cancer Cancer Research. 70: 644-644. DOI: 10.1158/1538-7445.Am10-644 |
0.827 |
|
2009 |
Maehr H, Lee HJ, Perry B, Suh N, Uskokovic MR. Calcitriol derivatives with two different side chains at C-20. V. Potent inhibitors of mammary carcinogenesis and inducers of leukemia differentiation. Journal of Medicinal Chemistry. 52: 5505-19. PMID 19685888 DOI: 10.1021/Jm900780Q |
0.366 |
|
2009 |
Paul S, Rimando AM, Lee HJ, Ji Y, Reddy BS, Suh N. Anti-inflammatory action of pterostilbene is mediated through the p38 mitogen-activated protein kinase pathway in colon cancer cells. Cancer Prevention Research (Philadelphia, Pa.). 2: 650-7. PMID 19549798 DOI: 10.1158/1940-6207.Capr-08-0224 |
0.789 |
|
2009 |
Lee HJ, Ju J, Paul S, So JY, DeCastro A, Smolarek A, Lee MJ, Yang CS, Newmark HL, Suh N. Mixed tocopherols prevent mammary tumorigenesis by inhibiting estrogen action and activating PPAR-gamma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4242-9. PMID 19509159 DOI: 10.1158/1078-0432.Ccr-08-3028 |
0.776 |
|
2009 |
Barve A, Khor TO, Nair S, Reuhl K, Suh N, Reddy B, Newmark H, Kong AN. Gamma-tocopherol-enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice. International Journal of Cancer. 124: 1693-9. PMID 19115203 DOI: 10.1002/Ijc.24106 |
0.365 |
|
2008 |
Lee HJ, Paul S, Atalla N, Thomas PE, Lin X, Yang I, Buckley B, Lu G, Zheng X, Lou YR, Conney AH, Maehr H, Adorini L, Uskokovic M, Suh N. Gemini vitamin D analogues inhibit estrogen receptor-positive and estrogen receptor-negative mammary tumorigenesis without hypercalcemic toxicity. Cancer Prevention Research (Philadelphia, Pa.). 1: 476-84. PMID 19138995 DOI: 10.1158/1940-6207.Capr-08-0084 |
0.809 |
|
2008 |
Rimando AM, Suh N. Biological/chemopreventive activity of stilbenes and their effect on colon cancer Planta Medica. 74: 1635-1643. PMID 18843589 DOI: 10.1055/S-0028-1088301 |
0.415 |
|
2008 |
Liu Y, Xiao H, Tian Y, Nekrasova T, Hao X, Lee HJ, Suh N, Yang CS, Minden A. The pak4 protein kinase plays a key role in cell survival and tumorigenesis in athymic mice. Molecular Cancer Research : McR. 6: 1215-24. PMID 18644984 DOI: 10.1158/1541-7786.Mcr-08-0087 |
0.437 |
|
2008 |
Rimando AM, Suh N. Natural products and dietary prevention of cancer. Molecular Nutrition & Food Research. 52: S5. PMID 18567050 DOI: 10.1002/Mnfr.200890027 |
0.36 |
|
2008 |
Lee HJ, Paul S, Ji Y, Atalla N, Thomas PE, Maehr H, Uskokovic M, Suh N. Abstract 2097: Gemini vitamin D analogs inhibit estrogen receptor positive and estrogen receptor negative mammary tumorigenesis without hypercalcemic toxicity Prevention and Research. DOI: 10.1158/1538-7445.Am2008-2097 |
0.758 |
|
2007 |
Lee HJ, Ji Y, Paul S, Maehr H, Uskokovic M, Suh N. Activation of bone morphogenetic protein signaling by a Gemini vitamin D3 analogue is mediated by Ras/protein kinase C alpha. Cancer Research. 67: 11840-7. PMID 18089814 DOI: 10.1158/0008-5472.Can-07-1549 |
0.765 |
|
2007 |
Suh N, Paul S, Lee HJ, Ji Y, Lee MJ, Yang CS, Reddy BS, Newmark HL. Mixed tocopherols inhibit N-methyl-N-nitrosourea-induced mammary tumor growth in rats. Nutrition and Cancer. 59: 76-81. PMID 17927505 DOI: 10.1080/01635580701419022 |
0.781 |
|
2007 |
Koschmieder S, D'Alò F, Radomska H, Schöneich C, Chang JS, Konopleva M, Kobayashi S, Levantini E, Suh N, Di Ruscio A, Voso MT, Watt JC, Santhanam R, Sargin B, Kantarjian H, et al. CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer binding protein alpha. Blood. 110: 3695-705. PMID 17671235 DOI: 10.1182/Blood-2006-11-058941 |
0.355 |
|
2007 |
Liby K, Honda T, Williams CR, Risingsong R, Royce DB, Suh N, Dinkova-Kostova AT, Stephenson KK, Talalay P, Sundararajan C, Gribble GW, Sporn MB. Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities Molecular Cancer Therapeutics. 6: 2113-2119. PMID 17620440 DOI: 10.1158/1535-7163.Mct-07-0180 |
0.397 |
|
2007 |
Maehr H, Uskokovic M, Adorini L, Penna G, Mariani R, Panina P, Passini N, Bono E, Perego S, Biffi M, Holick M, Spina C, Suh N. Calcitriol derivatives with two different side chains at C-20 III. An epimeric pair of the gemini family with unprecedented antiproliferative effects on tumor cells and renin mRNA expression inhibition. The Journal of Steroid Biochemistry and Molecular Biology. 103: 277-81. PMID 17254779 DOI: 10.1016/J.Jsbmb.2006.12.001 |
0.435 |
|
2007 |
Suh N, Paul S, Hao X, Simi B, Xiao H, Rimando AM, Reddy BS. Pterostilbene, an active constituent of blueberries, suppresses aberrant crypt foci formation in the azoxymethane-induced colon carcinogenesis model in rats. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 350-5. PMID 17200374 DOI: 10.1158/1078-0432.Ccr-06-1528 |
0.771 |
|
2006 |
Liby K, Rendi M, Suh N, Royce DB, Risingsong R, Williams CR, Lamph W, Labrie F, Krajewski S, Xu X, Kim H, Brown P, Sporn MB. The combination of the rexinoid, LG100268, and a selective estrogen receptor modulator, either arzoxifene or acolbifene, synergizes in the prevention and treatment of mammary tumors in an estrogen receptor-negative model of breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5902-9. PMID 17020999 DOI: 10.1158/1078-0432.Ccr-06-1119 |
0.427 |
|
2006 |
Banach-Petrosky W, Ouyang X, Gao H, Nader K, Ji Y, Suh N, DiPaola RS, Abate-Shen C. Vitamin D inhibits the formation of prostatic intraepithelial neoplasia in Nkx3.1;Pten mutant mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5895-901. PMID 17020998 DOI: 10.1158/1078-0432.Ccr-06-1039 |
0.337 |
|
2006 |
Honda T, Liby KT, Su X, Sundararajan C, Honda Y, Suh N, Risingsong R, Williams CR, Royce DB, Sporn MB, Gribble GW. Design, synthesis, and anti-inflammatory activity both in vitro and in vivo of new betulinic acid analogues having an enone functionality in ring A. Bioorganic & Medicinal Chemistry Letters. 16: 6306-9. PMID 16996735 DOI: 10.1016/J.Bmcl.2006.09.012 |
0.307 |
|
2006 |
Ji Y, Lee HJ, Goodman C, Uskokovic M, Liby K, Sporn M, Suh N. The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells. Molecular Cancer Therapeutics. 5: 1452-8. PMID 16818503 DOI: 10.1158/1535-7163.Mct-06-0136 |
0.362 |
|
2006 |
Lee HJ, Liu H, Goodman C, Ji Y, Maehr H, Uskokovic M, Notterman D, Reiss M, Suh N. Gene expression profiling changes induced by a novel Gemini Vitamin D derivative during the progression of breast cancer. Biochemical Pharmacology. 72: 332-43. PMID 16737686 DOI: 10.1016/J.Bcp.2006.04.030 |
0.477 |
|
2006 |
Lee HJ, Wislocki A, Goodman C, Ji Y, Ge R, Maehr H, Uskokovic M, Reiss M, Suh N. A novel vitamin D derivative activates bone morphogenetic protein signaling in MCF10 breast epithelial cells. Molecular Pharmacology. 69: 1840-8. PMID 16533909 DOI: 10.1124/Mol.105.022079 |
0.446 |
|
2006 |
Hong J, Sang S, Park HJ, Kwon SJ, Suh N, Huang MT, Ho CT, Yang CS. Modulation of arachidonic acid metabolism and nitric oxide synthesis by garcinol and its derivatives. Carcinogenesis. 27: 278-86. PMID 16093250 DOI: 10.1093/Carcin/Bgi208 |
0.334 |
|
2005 |
Hyer ML, Croxton R, Krajewska M, Krajewski S, Kress CL, Lu M, Suh N, Sporn MB, Cryns VL, Zapata JM, Reed JC. Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells. Cancer Research. 65: 4799-808. PMID 15930300 DOI: 10.1158/0008-5472.Can-04-3319 |
0.458 |
|
2005 |
Liby K, Hock T, Yore MM, Suh N, Place AE, Risingsong R, Williams CR, Royce DB, Honda T, Honda Y, Gribble GW, Hill-Kapturczak N, Agarwal A, Sporn MB. The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling. Cancer Research. 65: 4789-98. PMID 15930299 DOI: 10.1158/0008-5472.Can-04-4539 |
0.345 |
|
2005 |
Dinkova-Kostova AT, Liby KT, Stephenson KK, Holtzclaw WD, Gao X, Suh N, Williams C, Risingsong R, Honda T, Gribble GW, Sporn MB, Talalay P. Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress Proceedings of the National Academy of Sciences of the United States of America. 102: 4584-4589. PMID 15767573 DOI: 10.1073/Pnas.0500815102 |
0.323 |
|
2005 |
Koschmieder S, D′Alo′ F, Radomska H, Kobayashi S, Levantini E, Suh N, Sporn MB, Di Ruscio A, Voso MT, Berdel WE, Müller-Tidow C, Serve H, Tenen DG. CDDO Increases Translation of CCAAT Enhancer Binding Protein alpha To Induce Granulocytic Differentiation. Blood. 106: 2458-2458. DOI: 10.1182/Blood.V106.11.2458.2458 |
0.366 |
|
2004 |
Rendi MH, Suh N, Lamph WW, Krajewski S, Reed JC, Heyman RA, Berchuck A, Liby K, Risingsong R, Royce DB, Williams CR, Sporn MB. The selective estrogen receptor modulator arzoxifene and the rexinoid LG100268 cooperate to promote transforming growth factor beta-dependent apoptosis in breast cancer. Cancer Research. 64: 3566-71. PMID 15150113 DOI: 10.1158/0008-5472.Can-04-0234 |
0.465 |
|
2004 |
Dragnev KH, Pitha-Rowe I, Ma Y, Petty WJ, Sekula D, Murphy B, Rendi M, Suh N, Desai NB, Sporn MB, Freemantle SJ, Dmitrovsky E. Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: implications for combination therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2570-7. PMID 15073138 DOI: 10.1158/1078-0432.Ccr-03-0271 |
0.332 |
|
2004 |
Chauhan D, Li G, Podar K, Hideshima T, Shringarpure R, Catley L, Mitsiades C, Munshi N, Tai YT, Suh N, Gribble GW, Honda T, Schlossman R, Richardson P, Sporn MB, et al. The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti-multiple myeloma (MM) activity and overcome bortezomib resistance. Blood. 103: 3158-66. PMID 15070698 DOI: 10.1182/Blood-2003-08-2873 |
0.318 |
|
2004 |
Mix KS, Coon CI, Rosen ED, Suh N, Sporn MB, Brinckerhoff CE. Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling. Molecular Pharmacology. 65: 309-18. PMID 14742672 DOI: 10.1124/Mol.65.2.309 |
0.304 |
|
2003 |
Suh WS, Kim YS, Schimmer AD, Kitada S, Minden M, Andreeff M, Suh N, Sporn M, Reed JC. Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL Leukemia. 17: 2122-2129. PMID 12931220 DOI: 10.1038/Sj.Leu.2403112 |
0.305 |
|
2003 |
Place AE, Suh N, Williams CR, Risingsong R, Honda T, Honda Y, Gribble GW, Leesnitzer LM, Stimmel JB, Willson TM, Rosen E, Sporn MB. The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 2798-806. PMID 12855660 |
0.368 |
|
2002 |
Suh N, Lamph WW, Glasebrook AL, Grese TA, Palkowitz AD, Williams CR, Risingsong R, Farris MR, Heyman RA, Sporn MB. Prevention and treatment of experimental breast cancer with the combination of a new selective estrogen receptor modulator, arzoxifene, and a new rexinoid, LG 100268. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 3270-5. PMID 12374698 |
0.315 |
|
2002 |
Sporn MB, Suh N. Chemoprevention: an essential approach to controlling cancer. Nature Reviews. Cancer. 2: 537-43. PMID 12094240 DOI: 10.1038/Nrc844 |
0.343 |
|
2002 |
Kim Y, Suh N, Sporn M, Reed JC. An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis. The Journal of Biological Chemistry. 277: 22320-9. PMID 11940602 DOI: 10.1074/Jbc.M202458200 |
0.404 |
|
2002 |
Stadheim TA, Suh N, Ganju N, Sporn MB, Eastman A. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells. The Journal of Biological Chemistry. 277: 16448-55. PMID 11880365 DOI: 10.1074/Jbc.M108974200 |
0.35 |
|
2002 |
Konopleva M, Tsao T, Ruvolo P, Stiouf I, Estrov Z, Leysath CE, Zhao S, Harris D, Chang S, Jackson CE, Munsell M, Suh N, Gribble G, Honda T, May WS, et al. Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia. Blood. 99: 326-35. PMID 11756188 DOI: 10.1182/Blood.V99.1.326 |
0.378 |
|
2001 |
Sporn MB, Suh N, Mangelsdorf DJ. Prospects for prevention and treatment of cancer with selective PPARγ modulators (SPARMs) Trends in Molecular Medicine. 7: 395-400. PMID 11530334 DOI: 10.1016/S1471-4914(01)02100-1 |
0.429 |
|
2000 |
Honda T, Gribble GW, Suh N, Finlay HJ, Rounds BV, Bore L, Favaloro FG, Wang Y, Sporn MB. Novel synthetic oleanane and ursane triterpenoids with various enone functionalities in ring A as inhibitors of nitric oxide production in mouse macrophages. Journal of Medicinal Chemistry. 43: 1866-77. PMID 10794703 DOI: 10.1021/Jm000008J |
0.31 |
|
2000 |
Sporn MB, Suh N. Chemoprevention of cancer Carcinogenesis. 21: 525-530. PMID 10688873 DOI: 10.1093/Carcin/21.3.525 |
0.327 |
|
1996 |
Luyengi L, Suh N, Fong HH, Pezzuto JM, Kinghorn AD. A lignan and four terpenoids from Brucea javanica that induce differentiation with cultured HL-60 promyelocytic leukemia cells. Phytochemistry. 43: 409-12. PMID 8862033 DOI: 10.1016/0031-9422(96)00258-0 |
0.338 |
|
1995 |
Gerhäuser C, Mar W, Lee SK, Suh N, Luo Y, Kosmeder J, Luyengi L, Fong HHS, KingHorn AD, Moriarty RM, Mehta RG, Constantinou A, Moon RC, Pezzuto JM. Rotenoids mediate potent cancer chemopreventive activity through transcriptional regulation of ornithine decarboxylase. Nature Medicine. 1: 260-266. PMID 7585044 DOI: 10.1038/Nm0395-260 |
0.385 |
|
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