Olga Kovalchuk - Publications

Affiliations: 
Biological Studies University of Lethbridge (Canada) 
Area:
Cell Biology, Molecular Biology, Genetics

161 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Robinson GI, Li D, Wang B, Rahman T, Gerasymchuk M, Hudson D, Kovalchuk O, Kovalchuk I. Psilocybin and Eugenol Reduce Inflammation in Human 3D EpiIntestinal Tissue. Life (Basel, Switzerland). 13. PMID 38137946 DOI: 10.3390/life13122345  0.482
2023 Gojani EG, Wang B, Li DP, Kovalchuk O, Kovalchuk I. Anti-Inflammatory Properties of Eugenol in Lipopolysaccharide-Induced Macrophages and Its Role in Preventing β-Cell Dedifferentiation and Loss Induced by High Glucose-High Lipid Conditions. Molecules (Basel, Switzerland). 28. PMID 38005341 DOI: 10.3390/molecules28227619  0.51
2023 Cherkasova V, Ilnytskyy Y, Kovalchuk O, Kovalchuk I. Transcriptome Analysis of Cisplatin, Cannabidiol, and Intermittent Serum Starvation Alone and in Various Combinations on Colorectal Cancer Cells. International Journal of Molecular Sciences. 24. PMID 37834191 DOI: 10.3390/ijms241914743  0.539
2023 Gojani EG, Wang B, Li DP, Kovalchuk O, Kovalchuk I. Anti-Inflammatory Effects of Minor Cannabinoids CBC, THCV, and CBN in Human Macrophages. Molecules (Basel, Switzerland). 28. PMID 37764262 DOI: 10.3390/molecules28186487  0.526
2023 Wang B, Li D, Fiselier A, Kovalchuk I, Kovalchuk O. High-CBD cannabis extracts inhibit the expression of proinflammatory factors via miRNA-mediated silencing in human small intestinal epithelial cells. Heliyon. 9: e18817. PMID 37664748 DOI: 10.1016/j.heliyon.2023.e18817  0.507
2023 Ilnytskyy Y, Petersen L, McIntyre JB, Konno M, D'Silva A, Dean M, Elegbede A, Golubov A, Kovalchuk O, Kovalchuk I, Bebb G. Genome-wide Detection of Chimeric Transcripts in Early-stage Non-small Cell Lung Cancer. Cancer Genomics & Proteomics. 20: 417-432. PMID 37643782 DOI: 10.21873/cgp.20394  0.513
2023 Robinson GI, Li D, Wang B, Zahoruiko Y, Gerasymchuk M, Hudson D, Kovalchuk O, Kovalchuk I. Anti-Inflammatory Effects of Serotonin Receptor and Transient Receptor Potential Channel Ligands in Human Small Intestinal Epithelial Cells. Current Issues in Molecular Biology. 45: 6743-6774. PMID 37623246 DOI: 10.3390/cimb45080427  0.499
2023 Zaiachuk M, Suryavanshi SV, Pryimak N, Kovalchuk I, Kovalchuk O. The Anti-Inflammatory Effects of Extracts on LPS-Induced Cytokines Release in Human Macrophages. Molecules (Basel, Switzerland). 28. PMID 37446655 DOI: 10.3390/molecules28134991  0.472
2023 Zanikov T, Gerasymchuk M, Ghasemi Gojani E, Robinson GI, Asghari S, Groves A, Haselhorst L, Nandakumar S, Stahl C, Cameron M, Li D, Rodriguez-Juarez R, Snelling A, Hudson D, Fiselier A, ... Kovalchuk O, et al. The Effect of Combined Treatment of Psilocybin and Eugenol on Lipopolysaccharide-Induced Brain Inflammation in Mice. Molecules (Basel, Switzerland). 28. PMID 36985596 DOI: 10.3390/molecules28062624  0.492
2022 Gerasymchuk M, Robinson GI, Groves A, Haselhorst L, Nandakumar S, Stahl C, Kovalchuk O, Kovalchuk I. Phytocannabinoids Stimulate Rejuvenation and Prevent Cellular Senescence in Human Dermal Fibroblasts. Cells. 11. PMID 36497198 DOI: 10.3390/cells11233939  0.526
2022 Cherkasova V, Wang B, Gerasymchuk M, Fiselier A, Kovalchuk O, Kovalchuk I. Use of Cannabis and Cannabinoids for Treatment of Cancer. Cancers. 14. PMID 36291926 DOI: 10.3390/cancers14205142  0.515
2022 Ghasemi-Gojani E, Kovalchuk I, Kovalchuk O. Cannabinoids and terpenes for diabetes mellitus and its complications: from mechanisms to new therapies. Trends in Endocrinology and Metabolism: Tem. PMID 36280497 DOI: 10.1016/j.tem.2022.08.003  0.448
2022 Fiselier A, Byeon B, Ilnytskyy Y, Kovalchuk O, Kovalchuk I. Scatter Irradiation of Rat Brain Triggers Sex- and Brain Region-Specific Changes in the Expression of Non-Coding RNA Fragments. Epigenomes. 6. PMID 36278681 DOI: 10.3390/epigenomes6040035  0.53
2022 Li D, Ilnytskyy Y, Ghasemi Gojani E, Kovalchuk O, Kovalchuk I. Analysis of Anti-Cancer and Anti-Inflammatory Properties of 25 High-THC Cannabis Extracts. Molecules (Basel, Switzerland). 27. PMID 36144796 DOI: 10.3390/molecules27186057  0.507
2022 Wang B, Li D, Ilnytskyy Y, Kovalchuk I, Kovalchuk O. A miR-34a-guided, tRNA-derived, piR_019752-like fragment (tRiMetF31) suppresses migration and angiogenesis of breast cancer cells via targeting PFKFB3. Cell Death Discovery. 8: 355. PMID 35961977 DOI: 10.1038/s41420-022-01054-w  0.52
2022 Gerasymchuk M, Robinson GI, Kovalchuk O, Kovalchuk I. The Effects of Nutrient Signaling Regulators in Combination with Phytocannabinoids on the Senescence-Associated Phenotype in Human Dermal Fibroblasts. International Journal of Molecular Sciences. 23. PMID 35955938 DOI: 10.3390/ijms23158804  0.495
2022 Gerasymchuk M, Robinson GI, Kovalchuk O, Kovalchuk I. Modeling of the Senescence-Associated Phenotype in Human Skin Fibroblasts. International Journal of Molecular Sciences. 23. PMID 35806127 DOI: 10.3390/ijms23137124  0.53
2022 Suryavanshi SV, Zaiachuk M, Pryimak N, Kovalchuk I, Kovalchuk O. Cannabinoids Alleviate the LPS-Induced Cytokine Storm via Attenuating NLRP3 Inflammasome Signaling and TYK2-Mediated STAT3 Signaling Pathways In Vitro. Cells. 11. PMID 35563697 DOI: 10.3390/cells11091391  0.484
2022 Fiselier A, Byeon B, Ilnytskyy Y, Kovalchuk I, Kovalchuk O. Sex-Specific Expression of Non-Coding RNA Fragments in Frontal Cortex, Hippocampus and Cerebellum of Rats. Epigenomes. 6. PMID 35466186 DOI: 10.3390/epigenomes6020011  0.474
2022 Wang B, Li D, Cherkasova V, Gerasymchuk M, Narendran A, Kovalchuk I, Kovalchuk O. Cannabinol Inhibits Cellular Proliferation, Invasion, and Angiogenesis of Neuroblastoma via Novel miR-34a/tRiMetF31/PFKFB3 Axis. Cancers. 14. PMID 35454815 DOI: 10.3390/cancers14081908  0.5
2022 Malach M, Kovalchuk I, Kovalchuk O. Medical Cannabis in Pediatric Oncology: Friend or Foe? Pharmaceuticals (Basel, Switzerland). 15. PMID 35337156 DOI: 10.3390/ph15030359  0.488
2022 Wang B, Li D, Fiselier A, Kovalchuk I, Kovalchuk O. New AKT-dependent mechanisms of anti-COVID-19 action of high-CBD Cannabis sativa extracts. Cell Death Discovery. 8: 110. PMID 35277472 DOI: 10.1038/s41420-022-00876-y  0.493
2021 Pryimak N, Zaiachuk M, Kovalchuk O, Kovalchuk I. The Potential Use of Cannabis in Tissue Fibrosis. Frontiers in Cell and Developmental Biology. 9: 715380. PMID 34708034 DOI: 10.3389/fcell.2021.715380  0.476
2021 Zaiachuk M, Pryimak N, Kovalchuk O, Kovalchuk I. Cannabinoids, Medical Cannabis, and Colorectal Cancer Immunotherapy. Frontiers in Medicine. 8: 713153. PMID 34631734 DOI: 10.3389/fmed.2021.713153  0.522
2021 Cherkasova V, Kovalchuk O, Kovalchuk I. Cannabinoids and Endocannabinoid System Changes in Intestinal Inflammation and Colorectal Cancer. Cancers. 13. PMID 34503163 DOI: 10.3390/cancers13174353  0.514
2021 Kovalchuk A, Wang B, Li D, Rodriguez-Juarez R, Ilnytskyy S, Kovalchuk I, Kovalchuk O. Fighting the storm: could novel anti-TNFα and anti-IL-6 cultivars tame cytokine storm in COVID-19? Aging. 13. PMID 33465050 DOI: 10.18632/aging.202500  0.499
2020 Suryavanshi SV, Kovalchuk I, Kovalchuk O. Cannabinoids as Key Regulators of Inflammasome Signaling: A Current Perspective. Frontiers in Immunology. 11: 613613. PMID 33584697 DOI: 10.3389/fimmu.2020.613613  0.5
2020 Borisov N, Ilnytskyy Y, Byeon B, Kovalchuk O, Kovalchuk I. System, Method and Software for Calculation of a Cannabis Drug Efficiency Index for the Reduction of Inflammation. International Journal of Molecular Sciences. 22. PMID 33396562 DOI: 10.3390/ijms22010388  0.496
2020 Wang B, Kovalchuk A, Li D, Rodriguez-Juarez R, Ilnytskyy Y, Kovalchuk I, Kovalchuk O. In search of preventative strategies: novel high-CBD extracts modulate ACE2 expression in COVID-19 gateway tissues. Aging. 12. PMID 33221759 DOI: 10.18632/aging.202225  0.525
2020 Gerasymchuk M, Cherkasova V, Kovalchuk O, Kovalchuk I. The Role of microRNAs in Organismal and Skin Aging. International Journal of Molecular Sciences. 21. PMID 32722415 DOI: 10.3390/Ijms21155281  0.548
2020 Kovalchuk O, Kovalchuk I. Cannabinoids as anticancer therapeutic agents. Cell Cycle (Georgetown, Tex.). 19: 961-989. PMID 32249682 DOI: 10.1080/15384101.2020.1742952  0.548
2020 Kovalchuk O, Li D, Rodriguez-Juarez R, Golubov A, Hudson D, Kovalchuk I. The effect of cannabis dry flower irradiation on the level of cannabinoids, terpenes and anti-cancer properties of the extracts Biocatalysis and Agricultural Biotechnology. 29: 101736. DOI: 10.1016/J.Bcab.2020.101736  0.579
2019 Wang B, Li D, Yao Y, Mieke H, Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Bronson RT, Metz GAS, Kovalchuk O, Kovalchuk I. The crucial role of DNA-dependent protein kinase and myelin transcription factor 1-like protein in the miR-141 tumor suppressor network. Cell Cycle (Georgetown, Tex.). 1-17. PMID 31522595 DOI: 10.1080/15384101.2019.1652033  0.554
2019 Swift L, Zhang C, Kovalchuk O, Boklan J, Trippett T, Narendran A. Dual functionality of the antimicrobial agent taurolidine which demonstrates effective anti-tumor properties in pediatric neuroblastoma. Investigational New Drugs. PMID 31264069 DOI: 10.1007/S10637-019-00816-1  0.317
2019 Narendran N, Luzhna L, Kovalchuk O. Sex Difference of Radiation Response in Occupational and Accidental Exposure. Frontiers in Genetics. 10: 260. PMID 31130979 DOI: 10.3389/Fgene.2019.00260  0.785
2019 Swift L, Zhang C, Pfaffle A, Chew P, Kovalchuk O, Trippett TM, Narendran A. Effective targeted antitumor activity of the antimicrobial agent taurolidine against relapsed/refractory neuroblastoma: Cytotoxicity, target modulation and tumor xenograft studies. Journal of Clinical Oncology. 37: e21502-e21502. DOI: 10.1200/Jco.2019.37.15_Suppl.E21502  0.318
2019 Zhang C, Sharma R, Satbir T, Cheney A, Vaske O, Sanders L, Boklan J, Lewis VA, Anderson R, Kovalchuk O, Lacayo NJ, Narendran A, Bielamowicz KJ. Establishing a Novel in Vitro Informed Precision Clinical Trial Pathway for Refractory Pediatric Leukemia Blood. 134: 2633-2633. DOI: 10.1182/Blood-2019-131444  0.308
2019 Bose P, Boylos A, Petersen L, Kovalchuk O, Kovalchuk I, Dean M, Itani D, Kopciuk K, Bebb G. MA04.10 Development and Validation of a Gene Expression-Based Prognostic Signature in Early-Stage Squamous Cell Carcinoma of the Lung Journal of Thoracic Oncology. 14: S263-S264. DOI: 10.1016/J.Jtho.2019.08.527  0.528
2018 Wang B, Li D, Rodriguez-Juarez R, Farfus A, Storozynsky Q, Malach M, Carpenter E, Filkowski J, Lykkesfeldt AE, Kovalchuk O. A suppressive role of guanine nucleotide-binding protein subunit beta-4 inhibited by DNA methylation in the growth of anti-estrogen resistant breast cancer cells. Bmc Cancer. 18: 817. PMID 30103729 DOI: 10.1186/S12885-018-4711-0  0.324
2018 Wang B, Li D, Kovalchuk I, Apel IJ, Chinnaiyan AM, Wóycicki RK, Cantor CR, Kovalchuk O. miR-34a directly targets tRNA precursors and affects cellular proliferation, cell cycle, and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29941603 DOI: 10.1073/Pnas.1703029115  0.767
2018 Cortese F, Klokov D, Osipov A, Stefaniak J, Moskalev A, Schastnaya J, Cantor C, Aliper A, Mamoshina P, Ushakov I, Sapetsky A, Vanhaelen Q, Alchinova I, Karganov M, Kovalchuk O, et al. Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization. Oncotarget. 9: 14692-14722. PMID 29581875 DOI: 10.18632/Oncotarget.24461  0.312
2018 Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Katz A, Sidransky D, Kolb B, Kovalchuk O. Growth of Triple Negative and Progesterone Positive Breast Cancer Causes Oxidative Stress and Down-Regulates Neuroprotective Transcription Factor NPAS4 and NPAS4-Regulated Genes in Hippocampal Tissues of TumorGraft Mice-an Aging Connection. Frontiers in Genetics. 9: 58. PMID 29556248 DOI: 10.3389/Fgene.2018.00058  0.322
2018 Kovalchuk A, Ilnytskyy Y, Woycicki R, Rodriguez-Juarez R, Metz GAS, Kovalchuk O. Adverse effects of paternal chemotherapy exposure on the progeny brain: intergenerational chemobrain. Oncotarget. 9: 10069-10082. PMID 29515791 DOI: 10.18632/Oncotarget.24311  0.74
2018 Sorokin M, Kholodenko R, Grekhova A, Suntsova M, Pustovalova M, Vorobyeva N, Kholodenko I, Malakhova G, Garazha A, Nedoluzhko A, Vasilov R, Poddubskaya E, Kovalchuk O, Adamyan L, Prassolov V, et al. Acquired resistance to tyrosine kinase inhibitors may be linked with the decreased sensitivity to X-ray irradiation. Oncotarget. 9: 5111-5124. PMID 29435166 DOI: 10.18632/Oncotarget.23700  0.376
2018 Borisov N, Tkachev V, Suntsova M, Kovalchuk O, Zhavoronkov A, Muchnik I, Buzdin A. A method of gene expression data transfer from cell lines to cancer patients for machine-learning prediction of drug efficiency. Cell Cycle (Georgetown, Tex.). 1-6. PMID 29251172 DOI: 10.1080/15384101.2017.1417706  0.308
2018 Hough CM, Purschke DN, Huang C, Titova LV, Kovalchuk O, Warkentin BJ, Hegmann FA. Topology-Based Prediction of Pathway Dysregulation Induced by Intense Terahertz Pulses in Human Skin Tissue Models Journal of Infrared, Millimeter, and Terahertz Waves. 39: 887-898. DOI: 10.1007/S10762-018-0512-4  0.345
2017 Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Katz A, Sidransky D, Kolb B, Kovalchuk O. Growth of malignant extracranial tumors alters microRNAome in the prefrontal cortex of TumorGraft mice. Oncotarget. 8: 88276-88293. PMID 29179434 DOI: 10.18632/Oncotarget.19835  0.301
2017 Petrov I, Suntsova M, Ilnitskaya E, Roumiantsev S, Sorokin M, Garazha A, Spirin P, Lebedev T, Gaifullin N, Larin S, Kovalchuk O, Konovalov D, Prassolov V, Roumiantsev A, Buzdin A. Gene expression and molecular pathway activation signatures of MYCN-amplified neuroblastomas. Oncotarget. 8: 83768-83780. PMID 29137381 DOI: 10.18632/Oncotarget.19662  0.307
2017 Sidler C, Kovalchuk O, Kovalchuk I. Epigenetic Regulation of Cellular Senescence and Aging. Frontiers in Genetics. 8: 138. PMID 29018479 DOI: 10.3389/Fgene.2017.00138  0.564
2017 Moskalev A, Anisimov V, Aliper A, Artemov A, Asadullah K, Belsky D, Baranova A, de Grey A, Dixit VD, Debonneuil E, Dobrovolskaya E, Fedichev P, Fedintsev A, Fraifeld V, Franceschi C, ... ... Kovalchuk O, et al. A review of the biomedical innovations for healthy longevity. Aging. PMID 28132958 DOI: 10.18632/Aging.101163  0.511
2017 Buzdin A, Sorokin M, Glusker A, Garazha A, Poddubskaya E, Shirokorad V, Naskhletashvili D, Kashintsev K, Sokov D, Suntsova M, Roumiantsev S, Kovalchuk O, Gaifullin N, Tkachev V, Borisov N. Activation of intracellular signaling pathways as a new type of biomarkers for selection of target anticancer drugs. Journal of Clinical Oncology. 35: e23142-e23142. DOI: 10.1200/Jco.2017.35.15_Suppl.E23142  0.315
2016 Koturbash I, Jadavji NM, Kutanzi K, Rodriguez-Juarez R, Kogosov D, Metz GAS, Kovalchuk O. Fractionated low-dose exposure to ionizing radiation leads to DNA damage, epigenetic dysregulation, and behavioral impairment. Environmental Epigenetics. 2: dvw025. PMID 29492301 DOI: 10.1093/Eep/Dvw025  0.366
2016 Buzdin AA, Artcibasova AV, Fedorova NF, Suntsova MV, Garazha AV, Sorokin MI, Allina D, Shalatonin M, Borisov NM, Zhavoronkov AA, Kovalchuk I, Kovalchuk O, Kushch AA. Early stage of cytomegalovirus infection suppresses host microRNA expression regulation in human fibroblasts. Cell Cycle (Georgetown, Tex.). 15: 3378-3389. PMID 28051642 DOI: 10.1080/15384101.2016.1241928  0.56
2016 Koturbash I, Merrifield M, Kovalchuk O. Fractionated exposure to low doses of ionizing radiation results in accumulation of DNA damage in mouse spleen tissue and activation of apoptosis in a p53/Atm-independent manner. International Journal of Radiation Biology. 1-8. PMID 27758128 DOI: 10.1080/09553002.2017.1231943  0.374
2016 Luzhna L, Kovalchuk O. Mammary gland and radiation: Knowns and unknowns. Cell Cycle (Georgetown, Tex.). 1-2. PMID 27392129 DOI: 10.1080/15384101.2016.1170262  0.787
2016 Luzhna L, Filkowski J, Kovalchuk O. High and low dose radiation effects on mammary adenocarcinoma cells - an epigenetic connection. Oncoscience. 3: 88-97. PMID 27226982 DOI: 10.18632/oncoscience.298  0.799
2016 Krishnan P, Ghosh S, Wang B, Li D, Berendt R, Mackey JR, Kovalchuk O, Damaraju S. Abstract B37: Small nucleolar RNAs – New players in breast cancer prognosis Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-B37  0.315
2015 Kovalchuk A, Mychasiuk R, Muhammad A, Hossain S, Ilnytskyy S, Ghose A, Kirkby C, Ghasroddashti E, Kovalchuk O, Kolb B. Liver irradiation causes distal bystander effects in the rat brain and affects animal behaviour. Oncotarget. PMID 26678032 DOI: 10.18632/Oncotarget.6596  0.322
2015 Luzhna L, Ilnytskyy Y, Kovalchuk O. Mobilization of LINE-1 in irradiated mammary gland tissue may potentially contribute to low dose radiation-induced genomic instability. Genes & Cancer. 6: 71-81. PMID 25821563 DOI: 10.18632/Genesandcancer.50  0.796
2015 Luzhna L, Kutanzi K, Kovalchuk O. Gene expression and epigenetic profiles of mammary gland tissue: insight into the differential predisposition of four rat strains to mammary gland cancer. Mutation Research. Genetic Toxicology and Environmental Mutagenesis. 779: 39-56. PMID 25813725 DOI: 10.1016/J.Mrgentox.2014.07.006  0.77
2015 Luzhna L, Lykkesfeldt AE, Kovalchuk O. Altered radiation responses of breast cancer cells resistant to hormonal therapy. Oncotarget. 6: 1678-94. PMID 25682200 DOI: 10.18632/Oncotarget.3188  0.785
2015 Sidler C, Li D, Kovalchuk O, Kovalchuk I. Development-dependent expression of DNA repair genes and epigenetic regulators in Arabidopsis plants exposed to ionizing radiation. Radiation Research. 183: 219-32. PMID 25594540 DOI: 10.1667/Rr13840.1  0.601
2015 Damaraju S, Krishnan P, George MS, Tuszynski J, Cass C, Goping I, Kovalchuk O. Abstract 3076: Post-transcriptional regulatory mechanisms contributing to the evolution of paclitaxel resistance in breast cancer model cell line, SKBR3 Cancer Research. 75: 3076-3076. DOI: 10.1158/1538-7445.Am2015-3076  0.351
2014 Luzhna L, Kovalchuk O. Low dose irradiation profoundly affects transcriptome and microRNAme in rat mammary gland tissues. Oncoscience. 1: 751-62. PMID 25594002 DOI: 10.18632/oncoscience.94  0.795
2014 Sidler C, Li D, Wang B, Kovalchuk I, Kovalchuk O. SUV39H1 downregulation induces deheterochromatinization of satellite regions and senescence after exposure to ionizing radiation. Frontiers in Genetics. 5: 411. PMID 25484892 DOI: 10.3389/Fgene.2014.00411  0.647
2014 Kovalchuk IP, Golubov A, Koturbash IV, Kutanzi K, Martin OA, Kovalchuk O. Age-dependent changes in DNA repair in radiation-exposed mice. Radiation Research. 182: 683-94. PMID 25409128 DOI: 10.1667/RR13697.1  0.564
2014 Yao Y, Robinson AM, Zucchi FC, Robbins JC, Babenko O, Kovalchuk O, Kovalchuk I, Olson DM, Metz GA. Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes. Bmc Medicine. 12: 121. PMID 25286408 DOI: 10.1186/S12916-014-0121-6  0.646
2014 Sidler C, Woycicki R, Kovalchuk I, Kovalchuk O. WI-38 senescence is associated with global and site-specific hypomethylation. Aging. 6: 564-74. PMID 25063771 DOI: 10.18632/aging.100679  0.774
2014 Sidler C, Woycicki R, Li D, Wang B, Kovalchuk I, Kovalchuk O. A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts. Aging. 6: 545-63. PMID 25063769 DOI: 10.18632/aging.100678  0.784
2014 Wang B, Li D, Kovalchuk A, Litvinov D, Kovalchuk O. Ionizing radiation-inducible miR-27b suppresses leukemia proliferation via targeting cyclin A2. International Journal of Radiation Oncology, Biology, Physics. 90: 53-62. PMID 24974217 DOI: 10.1016/J.Ijrobp.2014.04.055  0.35
2014 Zucchi FC, Yao Y, Ilnytskyy Y, Robbins JC, Soltanpour N, Kovalchuk I, Kovalchuk O, Metz GA. Lifetime stress cumulatively programs brain transcriptome and impedes stroke recovery: benefit of sensory stimulation. Plos One. 9: e92130. PMID 24651125 DOI: 10.1371/Journal.Pone.0092130  0.657
2014 Kovalchuk O, Walz P, Kovalchuk I. Does bacterial infection cause genome instability and cancer in the host cell? Mutation Research. 761: 1-14. PMID 24472301 DOI: 10.1016/J.Mrfmmm.2014.01.004  0.563
2014 Perinpanayagam M, Kovalchuk A, Ruan Y, Kang S, Jayanthan A, Kovalchuk O, Boklan J, Narendran A. Establishment and Drug Sensitivity, Gene Expression and Epigenetic Characterization of a Pediatric Leukemia Cell Line (POETIC1) with Primary Resistance to Decitabine Blood. 124: 983-983. DOI: 10.1182/Blood.V124.21.983.983  0.381
2014 Titova LV, Ayesheshim AK, Purschke D, Golubov A, Rodriguez-Juarez R, Woycicki R, Hegmann FA, Kovalchuk O. Effect of intense THz pulses on expression of genes associated with skin cancer and inflammatory skin conditions Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8941. DOI: 10.1117/12.2044167  0.737
2013 Zabolotneva AA, Zhavoronkov AA, Shegay PV, Gaifullin NM, Alekseev BY, Roumiantsev SA, Garazha AV, Kovalchuk O, Aravin A, Buzdin AA. A systematic experimental evaluation of microRNA markers of human bladder cancer. Frontiers in Genetics. 4: 247. PMID 24298280 DOI: 10.3389/Fgene.2013.00247  0.307
2013 Sidler C, Wóycicki R, Ilnytskyy Y, Metz G, Kovalchuk I, Kovalchuk O. Immunosenescence is associated with altered gene expression and epigenetic regulation in primary and secondary immune organs. Frontiers in Genetics. 4: 211. PMID 24151501 DOI: 10.3389/Fgene.2013.00211  0.782
2013 Titova LV, Ayesheshim AK, Golubov A, Rodriguez-Juarez R, Woycicki R, Hegmann FA, Kovalchuk O. Intense THz pulses down-regulate genes associated with skin cancer and psoriasis: a new therapeutic avenue? Scientific Reports. 3: 2363. PMID 23917523 DOI: 10.1038/Srep02363  0.735
2013 Kovalchuk A, Aladedunye F, Rodriguez-Juarez R, Li D, Thomas J, Kovalchuk O, Przybylski R. Novel antioxidants are not toxic to normal tissues but effectively kill cancer cells. Cancer Biology & Therapy. 14: 907-15. PMID 23917379 DOI: 10.4161/Cbt.25935  0.367
2013 Kovalchuk I, Walz P, Thomas J, Kovalchuk O. Genomic instability in liver cells caused by an LPS-induced bystander-like effect. Plos One. 8: e67342. PMID 23874414 DOI: 10.1371/Journal.Pone.0067342  0.541
2013 Luzhna L, Kathiria P, Kovalchuk O. Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond. Frontiers in Genetics. 4: 131. PMID 23874352 DOI: 10.3389/Fgene.2013.00131  0.779
2013 Kovalchuk I, Walz P, Thomas J, Kovalchuk O. The increased expression of proteins involved in proliferation, DNA repair and DNA methylation in spleen of mice exposed to E. coli O157:H7 lipopolysaccharide. Environmental and Molecular Mutagenesis. 54: 421-8. PMID 23813549 DOI: 10.1002/Em.21787  0.569
2013 Kutanzi K, Kovalchuk O. Exposure to estrogen and ionizing radiation causes epigenetic dysregulation, activation of mitogen-activated protein kinase pathways, and genome instability in the mammary gland of ACI rats. Cancer Biology & Therapy. 14: 564-73. PMID 23792640 DOI: 10.4161/Cbt.24599  0.404
2013 Kirkby C, Ghasroddashti E, Kovalchuk A, Kolb B, Kovalchuk O. Monte Carlo-based dose reconstruction in a rat model for scattered ionizing radiation investigations. International Journal of Radiation Biology. 89: 741-9. PMID 23593950 DOI: 10.3109/09553002.2013.791407  0.301
2013 Titova LV, Ayesheshim AK, Golubov A, Fogen D, Rodriguez-Juarez R, Hegmann FA, Kovalchuk O. Intense THz pulses cause H2AX phosphorylation and activate DNA damage response in human skin tissue. Biomedical Optics Express. 4: 559-68. PMID 23577291 DOI: 10.1364/Boe.4.000559  0.356
2013 Merrifield M, Kovalchuk O. Epigenetics in radiation biology: a new research frontier. Frontiers in Genetics. 4: 40. PMID 23577019 DOI: 10.3389/Fgene.2013.00040  0.384
2013 Luzhna L, Golubov A, Ilnytskyy S, Chekhun VF, Kovalchuk O. Molecular mechanisms of radiation resistance in doxorubicin-resistant breast adenocarcinoma cells. International Journal of Oncology. 42: 1692-708. PMID 23467667 DOI: 10.3892/Ijo.2013.1845  0.803
2013 Zucchi FC, Yao Y, Ward ID, Ilnytskyy Y, Olson DM, Benzies K, Kovalchuk I, Kovalchuk O, Metz GA. Maternal stress induces epigenetic signatures of psychiatric and neurological diseases in the offspring. Plos One. 8: e56967. PMID 23451123 DOI: 10.1371/Journal.Pone.0056967  0.691
2013 Koch MW, Metz LM, Kovalchuk O. Epigenetics and miRNAs in the diagnosis and treatment of multiple sclerosis. Trends in Molecular Medicine. 19: 23-30. PMID 23153574 DOI: 10.1016/J.Molmed.2012.10.008  0.306
2013 Titova LV, Ayesheshim AK, Golubov A, Rodriguez-Juarez R, Kovalchuk A, Hegmann FA, Kovalchuk O. Intense picosecond THz pulses alter gene expression in human skin tissue in vivo Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8585. DOI: 10.1117/12.2004998  0.371
2013 Bose P, Filkowsky J, Bilichak A, Brockton NT, Kovalchuk O, Kovalchuk I, Dort JC. OP054 Oral Oncology. 49: S26. DOI: 10.1016/J.Oraloncology.2013.03.062  0.56
2011 Dickey JS, Zemp FJ, Martin OA, Kovalchuk O. The role of miRNA in the direct and indirect effects of ionizing radiation. Radiation and Environmental Biophysics. 50: 491-9. PMID 21928045 DOI: 10.1007/S00411-011-0386-5  0.324
2011 Ilnytskyy Y, Kovalchuk O. Non-targeted radiation effects-an epigenetic connection. Mutation Research. 714: 113-25. PMID 21784089 DOI: 10.1016/J.Mrfmmm.2011.06.014  0.417
2011 Hudson D, Kovalchuk I, Koturbash I, Kolb B, Martin OA, Kovalchuk O. Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals. Aging. 3: 609-20. PMID 21685513  0.559
2011 Dickey JS, Zemp FJ, Altamirano A, Sedelnikova OA, Bonner WM, Kovalchuk O. H2AX phosphorylation in response to DNA double-strand break formation during bystander signalling: effect of microRNA knockdown. Radiation Protection Dosimetry. 143: 264-9. PMID 21183548 DOI: 10.1093/Rpd/Ncq470  0.33
2011 Tamminga J, Kovalchuk O. Role of DNA damage and epigenetic DNA methylation changes in radiation-induced genomic instability and bystander effects in germline in vivo. Current Molecular Pharmacology. 4: 115-25. PMID 21143184 DOI: 10.2174/1874467211104020115  0.391
2011 Koturbash I, Zemp F, Kolb B, Kovalchuk O. Sex-specific radiation-induced microRNAome responses in the hippocampus, cerebellum and frontal cortex in a mouse model Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 722: 114-118. PMID 20478395 DOI: 10.1016/J.Mrgentox.2010.05.007  0.401
2011 Koturbash I, Zemp FJ, Pogribny I, Kovalchuk O. Small molecules with big effects: the role of the microRNAome in cancer and carcinogenesis. Mutation Research. 722: 94-105. PMID 20472093 DOI: 10.1016/J.Mrgentox.2010.05.006  0.342
2011 Shpyleva SI, Tryndyak VP, Kovalchuk O, Starlard-Davenport A, Chekhun VF, Beland FA, Pogribny IP. Role of ferritin alterations in human breast cancer cells. Breast Cancer Research and Treatment. 126: 63-71. PMID 20390345 DOI: 10.1007/S10549-010-0849-4  0.343
2010 Kutanzi KR, Koturbash I, Kovalchuk O. Reversibility of pre-malignant estrogen-induced epigenetic changes. Cell Cycle (Georgetown, Tex.). 9: 3078-84. PMID 20699652 DOI: 10.4161/Cc.9.15.12516  0.355
2010 Kutanzi KR, Koturbash I, Bronson RT, Pogribny IP, Kovalchuk O. Imbalance between apoptosis and cell proliferation during early stages of mammary gland carcinogenesis in ACI rats. Mutation Research. 694: 1-6. PMID 20659487 DOI: 10.1016/J.Mrfmmm.2010.07.006  0.376
2010 Kovalchuk O, Zemp FJ, Filkowski JN, Altamirano AM, Dickey JS, Jenkins-Baker G, Marino SA, Brenner DJ, Bonner WM, Sedelnikova OA. microRNAome changes in bystander three-dimensional human tissue models suggest priming of apoptotic pathways. Carcinogenesis. 31: 1882-8. PMID 20643754 DOI: 10.1093/Carcin/Bgq119  0.367
2010 Pogribny IP, Filkowski JN, Tryndyak VP, Golubov A, Shpyleva SI, Kovalchuk O. Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. International Journal of Cancer. 127: 1785-94. PMID 20099276 DOI: 10.1002/Ijc.25191  0.325
2010 Luzhna L, Kovalchuk O. Modulation of DNA methylation levels sensitizes doxorubicin-resistant breast adenocarcinoma cells to radiation-induced apoptosis. Biochemical and Biophysical Research Communications. 392: 113-7. PMID 20034463 DOI: 10.1016/J.Bbrc.2009.12.093  0.799
2010 Filkowski JN, Ilnytskyy Y, Tamminga J, Koturbash I, Golubov A, Bagnyukova T, Pogribny IP, Kovalchuk O. Hypomethylation and genome instability in the germline of exposed parents and their progeny is associated with altered miRNA expression. Carcinogenesis. 31: 1110-5. PMID 19959559 DOI: 10.1093/Carcin/Bgp300  0.357
2010 Shpyleva SI, Tryndyak VP, Kovalchuk O, Starlard-Davenport A, Chekhun VF, Beland FA, Pogribny IP. Abstract 2313: Role of ferritin dysregulation in human breast cancer cells Cancer Research. 70: 2313-2313. DOI: 10.1158/1538-7445.Am10-2313  0.346
2009 Koturbash I, Thomas JE, Kovalchuk O, Kovalchuk I. Heat-killed bacteria induce genome instability in mouse small intestine, liver and spleen tissues. Cell Cycle (Georgetown, Tex.). 8: 1935-9. PMID 19440049 DOI: 10.4161/Cc.8.12.8797  0.561
2009 Ilnytskyy Y, Koturbash I, Kovalchuk O. Radiation-induced bystander effects in vivo are epigenetically regulated in a tissue-specific manner. Environmental and Molecular Mutagenesis. 50: 105-13. PMID 19107897 DOI: 10.1002/Em.20440  0.385
2008 Kovalchuk I, Kovalchuk O. Transgenic Plants as Sensors of Environmental Pollution Genotoxicity. Sensors (Basel, Switzerland). 8: 1539-1558. PMID 27879779 DOI: 10.3390/S8031539  0.48
2008 Tamminga J, Kathiria P, Koturbash I, Kovalchuk O. DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation. Cell Cycle (Georgetown, Tex.). 7: 3731-6. PMID 19029807 DOI: 10.4161/Cc.7.23.7186  0.37
2008 Ilnytskyy Y, Zemp FJ, Koturbash I, Kovalchuk O. Altered microRNA expression patterns in irradiated hematopoietic tissues suggest a sex-specific protective mechanism. Biochemical and Biophysical Research Communications. 377: 41-5. PMID 18823940 DOI: 10.1016/J.Bbrc.2008.09.080  0.364
2008 Kovalchuk O, Filkowski J, Meservy J, Ilnytskyy Y, Tryndyak VP, Chekhun VF, Pogribny IP. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Molecular Cancer Therapeutics. 7: 2152-9. PMID 18645025 DOI: 10.1158/1535-7163.Mct-08-0021  0.348
2008 Koturbash I, Zemp FJ, Kutanzi K, Luzhna L, Loree J, Kolb B, Kovalchuk O. Sex-specific microRNAome deregulation in the shielded bystander spleen of cranially exposed mice Cell Cycle. 7: 1658-1667. PMID 18560276 DOI: 10.4161/Cc.7.11.5981  0.793
2008 Koturbash I, Kutanzi K, Hendrickson K, Rodriguez-Juarez R, Kogosov D, Kovalchuk O. Radiation-induced bystander effects in vivo are sex specific. Mutation Research. 642: 28-36. PMID 18508093 DOI: 10.1016/J.Mrfmmm.2008.04.002  0.389
2008 Tamminga J, Koturbash I, Baker M, Kutanzi K, Kathiria P, Pogribny IP, Sutherland RJ, Kovalchuk O. Paternal cranial irradiation induces distant bystander DNA damage in the germline and leads to epigenetic alterations in the offspring. Cell Cycle (Georgetown, Tex.). 7: 1238-45. PMID 18418050 DOI: 10.4161/Cc.7.9.5806  0.395
2008 Koturbash I, Loree J, Kutanzi K, Koganow C, Pogribny I, Kovalchuk O. In vivo bystander effect: cranial X-irradiation leads to elevated DNA damage, altered cellular proliferation and apoptosis, and increased p53 levels in shielded spleen. International Journal of Radiation Oncology, Biology, Physics. 70: 554-62. PMID 18207032 DOI: 10.1016/J.Ijrobp.2007.09.039  0.368
2008 Yauk C, Polyzos A, Rowan-Carroll A, Somers CM, Godschalk RW, Van Schooten FJ, Berndt ML, Pogribny IP, Koturbash I, Williams A, Douglas GR, Kovalchuk O. Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location. Proceedings of the National Academy of Sciences of the United States of America. 105: 605-10. PMID 18195365 DOI: 10.1073/Pnas.0705896105  0.318
2008 Kovalchuk O, Baulch JE. Epigenetic changes and nontargeted radiation effects--is there a link? Environmental and Molecular Mutagenesis. 49: 16-25. PMID 18172877 DOI: 10.1002/Em.20361  0.409
2008 Yauk CL, Polyzos A, Rowan-Carroll A, Kortubash I, Williams A, Kovalchuk O. Tandem repeat mutation, global DNA methylation, and regulation of DNA methyltransferases in cultured mouse embryonic fibroblast cells chronically exposed to chemicals with different modes of action. Environmental and Molecular Mutagenesis. 49: 26-35. PMID 18172875 DOI: 10.1002/Em.20359  0.33
2007 Pogribny IP, Bagnyukova TV, Tryndyak VP, Muskhelishvili L, Rodriguez-Juarez R, Kovalchuk O, Han T, Fuscoe JC, Ross SA, Beland FA. Gene expression profiling reveals underlying molecular mechanisms of the early stages of tamoxifen-induced rat hepatocarcinogenesis. Toxicology and Applied Pharmacology. 225: 61-9. PMID 17706260 DOI: 10.1016/J.Taap.2007.07.001  0.35
2007 Kovalchuk O, Tryndyak VP, Montgomery B, Boyko A, Kutanzi K, Zemp F, Warbritton AR, Latendresse JR, Kovalchuk I, Beland FA, Pogribny IP. Estrogen-induced rat breast carcinogenesis is characterized by alterations in DNA methylation, histone modifications and aberrant microRNA expression. Cell Cycle (Georgetown, Tex.). 6: 2010-8. PMID 17700064 DOI: 10.4161/Cc.6.16.4549  0.591
2007 Kovalchuk I, Molinier J, Yao Y, Arkhipov A, Kovalchuk O. Transcriptome analysis reveals fundamental differences in plant response to acute and chronic exposure to ionizing radiation. Mutation Research. 624: 101-13. PMID 17568626 DOI: 10.1016/J.Mrfmmm.2007.04.009  0.582
2007 Sedelnikova OA, Nakamura A, Kovalchuk O, Koturbash I, Mitchell SA, Marino SA, Brenner DJ, Bonner WM. DNA double-strand breaks form in bystander cells after microbeam irradiation of three-dimensional human tissue models. Cancer Research. 67: 4295-302. PMID 17483342 DOI: 10.1158/0008-5472.Can-06-4442  0.41
2007 Chekhun VF, Lukyanova NY, Kovalchuk O, Tryndyak VP, Pogribny IP. Epigenetic profiling of multidrug-resistant human MCF-7 breast adenocarcinoma cells reveals novel hyper- and hypomethylated targets. Molecular Cancer Therapeutics. 6: 1089-98. PMID 17363502 DOI: 10.1158/1535-7163.Mct-06-0663  0.361
2007 Koturbash I, Boyko A, Rodriguez-Juarez R, McDonald RJ, Tryndyak VP, Kovalchuk I, Pogribny IP, Kovalchuk O. Role of epigenetic effectors in maintenance of the long-term persistent bystander effect in spleen in vivo. Carcinogenesis. 28: 1831-8. PMID 17347136 DOI: 10.1093/Carcin/Bgm053  0.637
2007 Pogribny IP, Tryndyak VP, Boyko A, Rodriguez-Juarez R, Beland FA, Kovalchuk O. Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure. Mutation Research. 619: 30-7. PMID 17343880 DOI: 10.1016/J.Mrfmmm.2006.12.006  0.318
2007 Tryndyak VP, Kovalchuk O, Muskhelishvili L, Montgomery B, Rodriguez-Juarez R, Melnyk S, Ross SA, Beland FA, Pogribny IP. Epigenetic reprogramming of liver cells in tamoxifen-induced rat hepatocarcinogenesis. Molecular Carcinogenesis. 46: 187-97. PMID 17219426 DOI: 10.1002/Mc.20263  0.39
2006 Loree J, Koturbash I, Kutanzi K, Baker M, Pogribny I, Kovalchuk O. Radiation-induced molecular changes in rat mammary tissue: Possible implications for radiation-induced carcinogenesis International Journal of Radiation Biology. 82: 805-815. PMID 17148264 DOI: 10.1080/09553000600960027  0.375
2006 Koturbash I, Baker M, Loree J, Kutanzi K, Hudson D, Pogribny I, Sedelnikova O, Bonner W, Kovalchuk O. Epigenetic dysregulation underlies radiation-induced transgenerational genome instability in vivo International Journal of Radiation Oncology Biology Physics. 66: 327-330. PMID 16965987 DOI: 10.1016/J.Ijrobp.2006.06.012  0.371
2006 Tryndyak V, Kovalchuk O, Pogribny IP. Identification of differentially methylated sites within unmethylated DNA domains in normal and cancer cells. Analytical Biochemistry. 356: 202-7. PMID 16824473 DOI: 10.1016/J.Ab.2006.05.019  0.332
2006 Tryndyak VP, Muskhelishvili L, Kovalchuk O, Rodriguez-Juarez R, Montgomery B, Churchwell MI, Ross SA, Beland FA, Pogribny IP. Effect of long-term tamoxifen exposure on genotoxic and epigenetic changes in rat liver: implications for tamoxifen-induced hepatocarcinogenesis. Carcinogenesis. 27: 1713-20. PMID 16632870 DOI: 10.1093/Carcin/Bgl050  0.363
2006 Koturbash I, Rugo RE, Hendricks CA, Loree J, Thibault B, Kutanzi K, Pogribny I, Yanch JC, Engelward BP, Kovalchuk O. Irradiation induces DNA damage and modulates epigenetic effectors in distant bystander tissue in vivo. Oncogene. 25: 4267-75. PMID 16532033 DOI: 10.1038/Sj.Onc.1209467  0.396
2006 Tryndyak VP, Kovalchuk O, Pogribny IP. Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins. Cancer Biology & Therapy. 5: 65-70. PMID 16322686 DOI: 10.4161/Cbt.5.1.2288  0.359
2006 Cassie S, Koturbash I, Hudson D, Baker M, Ilnytskyy Y, Rodriguez-Juarez R, Weber E, Kovalchuk O. Novel retinoblastoma binding protein RBBP9 modulates sex-specific radiation responses in vivo Carcinogenesis. 27: 465-474. PMID 16272168 DOI: 10.1093/Carcin/Bgi261  0.377
2005 Pogribny I, Koturbash I, Tryndyak V, Hudson D, Stevenson SM, Sedelnikova O, Bonner W, Kovalchuk O. Fractionated low-dose radiation exposure leads to accumulation of DNA damage and profound alterations in DNA and histone methylation in the murine thymus. Molecular Cancer Research : McR. 3: 553-61. PMID 16254189 DOI: 10.1158/1541-7786.Mcr-05-0074  0.395
2005 Koturbash I, Pogribny I, Kovalchuk O. Stable loss of global DNA methylation in the radiation-target tissue--a possible mechanism contributing to radiation carcinogenesis? Biochemical and Biophysical Research Communications. 337: 526-33. PMID 16202973 DOI: 10.1016/J.Bbrc.2005.09.084  0.408
2005 Besplug J, Burke P, Ponton A, Filkowski J, Titov V, Kovalchuk I, Kovalchuk O. Sex and tissue-specific differences in low-dose radiation-induced oncogenic signaling. International Journal of Radiation Biology. 81: 157-68. PMID 16019925 DOI: 10.1080/09553000500103512  0.594
2005 Kovalchuk I, Titov V, Hohn B, Kovalchuk O. Transcriptome profiling reveals similarities and differences in plant responses to cadmium and lead. Mutation Research. 570: 149-61. PMID 15708574 DOI: 10.1016/J.Mrfmmm.2004.10.004  0.554
2004 Silasi G, Diaz-Heijtz R, Besplug J, Rodriguez-Juarez R, Titov V, Kolb B, Kovalchuk O. Selective brain responses to acute and chronic low-dose X-ray irradiation in males and females. Biochemical and Biophysical Research Communications. 325: 1223-35. PMID 15555557 DOI: 10.1016/J.Bbrc.2004.10.166  0.358
2004 Raiche J, Rodriguez-Juarez R, Pogribny I, Kovalchuk O. Sex- and tissue-specific expression of maintenance and de novo DNA methyltransferases upon low dose X-irradiation in mice. Biochemical and Biophysical Research Communications. 325: 39-47. PMID 15522198 DOI: 10.1016/J.Bbrc.2004.10.002  0.403
2004 Pogribny I, Raiche J, Slovack M, Kovalchuk O. Dose-dependence, sex- and tissue-specificity, and persistence of radiation-induced genomic DNA methylation changes. Biochemical and Biophysical Research Communications. 320: 1253-61. PMID 15249225 DOI: 10.1016/J.Bbrc.2004.06.081  0.395
2004 Besplug J, Filkowski J, Burke P, Kovalchuk I, Kovalchuk O. Atrazine induces homologous recombination but not point mutation in the transgenic plant-based biomonitoring assay. Archives of Environmental Contamination and Toxicology. 46: 296-300. PMID 15195800 DOI: 10.1007/S00244-003-3075-9  0.555
2004 Kovalchuk I, Pelczar P, Kovalchuk O. High frequency of nucleotide misincorporations upon the processing of double-strand breaks. Dna Repair. 3: 217-23. PMID 15177037 DOI: 10.1016/J.Dnarep.2003.09.011  0.559
2004 Kovalchuk O, Ponton A, Filkowski J, Kovalchuk I. Dissimilar genome response to acute and chronic low-dose radiation in male and female mice. Mutation Research. 550: 59-72. PMID 15135641 DOI: 10.1016/J.Mrfmmm.2004.02.007  0.6
2004 Kovalchuk I, Abramov V, Pogribny I, Kovalchuk O. Molecular aspects of plant adaptation to life in the Chernobyl zone. Plant Physiology. 135: 357-63. PMID 15133154 DOI: 10.1104/Pp.104.040477  0.61
2004 Kovalchuk O, Burke P, Besplug J, Slovack M, Filkowski J, Pogribny I. Methylation changes in muscle and liver tissues of male and female mice exposed to acute and chronic low-dose X-ray-irradiation. Mutation Research. 548: 75-84. PMID 15063138 DOI: 10.1016/J.Mrfmmm.2003.12.016  0.389
2004 Filkowski J, Kovalchuk O, Kovalchuk I. Genome stability of vtc1, tt4, and tt5 Arabidopsis thaliana mutants impaired in protection against oxidative stress. The Plant Journal : For Cell and Molecular Biology. 38: 60-9. PMID 15053760 DOI: 10.1111/J.1365-313X.2004.02020.X  0.582
2004 Filkowski J, Yeoman A, Kovalchuk O, Kovalchuk I. Systemic plant signal triggers genome instability. The Plant Journal : For Cell and Molecular Biology. 38: 1-11. PMID 15053755 DOI: 10.1111/J.1365-313X.2004.02025.X  0.564
2004 Filkowski J, Kovalchuk O, Kovalchuk I. Dissimilar mutation and recombination rates in Arabidopsis and tobacco Plant Science. 166: 265-272. DOI: 10.1016/J.Plantsci.2003.09.016  0.558
2003 Kovalchuk I, Kovalchuk O. A new use for transgenic plants--environmental biomonitors. Biotechnology & Genetic Engineering Reviews. 20: 23-45. PMID 14997845 DOI: 10.1080/02648725.2003.10648036  0.52
2003 Filkowski J, Besplug J, Burke P, Kovalchuk I, Kovalchuk O. Genotoxicity of 2,4-D and dicamba revealed by transgenic Arabidopsis thaliana plants harboring recombination and point mutation markers. Mutation Research. 542: 23-32. PMID 14644350 DOI: 10.1016/J.Mrgentox.2003.07.008  0.543
2003 Kovalchuk O, Burke P, Arkhipov A, Kuchma N, James SJ, Kovalchuk I, Pogribny I. Genome hypermethylation in Pinus silvestris of Chernobyl--a mechanism for radiation adaptation? Mutation Research. 529: 13-20. PMID 12943916 DOI: 10.1016/S0027-5107(03)00103-9  0.607
2003 Kovalchuk I, Kovalchuk O, Kalck V, Boyko V, Filkowski J, Heinlein M, Hohn B. Pathogen-induced systemic plant signal triggers DNA rearrangements. Nature. 423: 760-2. PMID 12802336 DOI: 10.1038/Nature01683  0.55
2003 Kovalchuk O, Kovalchuk I, Arkhipov A, Hohn B, Dubrova YE. Extremely complex pattern of microsatellite mutation in the germline of wheat exposed to the post-Chernobyl radioactive contamination. Mutation Research. 525: 93-101. PMID 12650909 DOI: 10.1016/S0027-5107(03)00006-X  0.541
2001 Kovalchuk I, Kovalchuk O, Hohn B. Biomonitoring the genotoxicity of environmental factors with transgenic plants. Trends in Plant Science. 6: 306-10. PMID 11435169 DOI: 10.1016/S1360-1385(01)01985-9  0.547
2001 Kovalchuk O, Titov V, Hohn B, Kovalchuk I. A sensitive transgenic plant system to detect toxic inorganic compounds in the environment. Nature Biotechnology. 19: 568-72. PMID 11385463 DOI: 10.1038/89327  0.531
2000 Kovalchuk O, Dubrova YE, Arkhipov A, Hohn B, Kovalchuk I. Wheat mutation rate after Chernobyl. Nature. 407: 583-4. PMID 11034198 DOI: 10.1038/35036692  0.567
2000 Kovalchuk I, Kovalchuk O, Hohn B. Genome-wide variation of the somatic mutation frequency in transgenic plants. The Embo Journal. 19: 4431-8. PMID 10970837 DOI: 10.1093/Emboj/19.17.4431  0.545
2000 Kovalchuk O, Arkhipov A, Barylyak I, Karachov I, Titov V, Hohn B, Kovalchuk I. Plants experiencing chronic internal exposure to ionizing radiation exhibit higher frequency of homologous recombination than acutely irradiated plants. Mutation Research. 449: 47-56. PMID 10751634 DOI: 10.1016/S0027-5107(00)00029-4  0.579
2000 Kovalchuk O, Kovalchuk I, Titov V, Arkhipov A, Hohn B. Radiation hazard caused by the Chernobyl accident in inhabited areas of Ukraine can be monitored by transgenic plants. Mutation Research. 446: 49-55. PMID 10613185 DOI: 10.1016/S1383-5718(99)00147-3  0.564
1999 Kovalchuk I, Kovalchuk O, Arkhipov A, Hohn B. Transgenic plants are sensitive bioindicators of nuclear pollution caused by the Chernobyl accident. Nature Biotechnology. 16: 1054-9. PMID 9831035 DOI: 10.1038/3505  0.578
1998 Kovalchuk O, Kovalchuk I, Arkhipov A, Telyuk P, Hohn B, Kovalchuk L. The Allium cepa chromosome aberration test reliably measures genotoxicity of soils of inhabited areas in the Ukraine contaminated by the Chernobyl accident. Mutation Research. 415: 47-57. PMID 9711261 DOI: 10.1016/S1383-5718(98)00053-9  0.518
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