Lucy A. Godley - Publications

Affiliations: 
Cancer Biology University of Chicago, Chicago, IL 
Area:
Oncology, Cell Biology

181 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Stubbins RJ, Korotev S, Godley LA. Germline CHEK2 and ATM Variants in Myeloid and Other Hematopoietic Malignancies. Current Hematologic Malignancy Reports. PMID 35674998 DOI: 10.1007/s11899-022-00663-7  0.319
2021 Samra N, Toubiana S, Yttervik H, Tzur-Gilat A, Morani I, Itzkovich C, Giladi L, Abu Jabal K, Cao JZ, Godley LA, Mory A, Baris Feldman H, Tveten K, Selig S, Weiss K. RBL2 bi-allelic truncating variants cause severe motor and cognitive impairment without evidence for abnormalities in DNA methylation or telomeric function. Journal of Human Genetics. PMID 33980986 DOI: 10.1038/s10038-021-00931-z  0.328
2020 Toubiana S, Larom G, Smoom R, Duszynski RJ, Godley LA, Francastel C, Velasco G, Selig S. Regulation of telomeric function by DNA methylation differs between humans and mice. Human Molecular Genetics. PMID 32916696 DOI: 10.1093/Hmg/Ddaa206  0.409
2020 Cao JZ, Liu H, Wickrema A, Godley LA. HIF-1 directly induces TET3 expression to enhance 5-hmC density and induce erythroid gene expression in hypoxia. Blood Advances. 4: 3053-3062. PMID 32634239 DOI: 10.1182/Bloodadvances.2020001535  0.388
2020 Kewan T, Noss R, Godley LA, Rogers HJ, Carraway HE. Inherited Thrombocytopenia Caused by Germline Mutation Should Be Considered in Young Patients With Suspected Myelodysplastic Syndrome. Journal of Investigative Medicine High Impact Case Reports. 8: 2324709620938941. PMID 32618208 DOI: 10.1177/2324709620938941  0.339
2020 Brown AL, Arts P, Carmichael CL, Babic M, Dobbins J, Chong CE, Schreiber AW, Feng J, Phillips K, Wang PPS, Ha T, Homan CC, King-Smith SL, Rawlings L, Vakulin C, ... ... Godley LA, et al. RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML. Blood Advances. 4: 1131-1144. PMID 32208489 DOI: 10.1182/Bloodadvances.2019000901  0.358
2020 Wu D, Luo X, Feurstein S, Kesserwan C, Mohan S, Pineda-Alvarez DE, Godley LA. How I curate: applying American Society of Hematology-Clinical Genome Resource Myeloid Malignancy Variant Curation Expert Panel rules for RUNX1 variant curation for germline predisposition to myeloid malignancies. Haematologica. PMID 32165484 DOI: 10.3324/Haematol.2018.214221  0.323
2020 Qiu Z, Lin AP, Jiang S, Elkashef SM, Myers J, Srikantan S, Sasi B, Cao JZ, Godley LA, Rakheja D, Lyu Y, Zheng S, Madesh M, Shiio Y, Dahia PLM, et al. MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome. Cell Chemical Biology. PMID 32101699 DOI: 10.1016/J.Chembiol.2020.02.002  0.33
2020 Cahill KE, Karimi YH, Karrison TG, Jain N, Green M, Weiner H, Fulton N, Kadri S, Godley LA, Artz AS, Liu H, Thirman MJ, Le Beau MM, McNerney ME, Segal J, et al. A phase 1 study of azacitidine with high-dose cytarabine and mitoxantrone in high-risk acute myeloid leukemia. Blood Advances. 4: 599-606. PMID 32074275 DOI: 10.1182/Bloodadvances.2019000795  0.305
2020 Kraft IL, Trottier AM, Steinhardt GF, Niu N, Wanjari P, Chen W, Segal J, Godley LA. Using sequential next-generation sequencing assays to identify germline cancer predisposition variants. Journal of Clinical Oncology. 38: 1581-1581. DOI: 10.1200/Jco.2020.38.15_Suppl.1581  0.337
2019 Applebaum MA, Barr EK, Karpus J, West-Szymanski DC, Oliva M, Sokol EA, Zhang S, Zhang Z, Zhang W, Chlenksi A, Salwen HR, Wilkinson E, Dobratic M, Grossman RL, Godley LA, et al. 5-hydroxymethylcytosine profiles in circulating cell-free DNA associate with disease burden in children with neuroblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31852832 DOI: 10.1158/1078-0432.Ccr-19-2829  0.388
2019 Luo X, Feurstein S, Mohan S, Porter CC, Jackson SA, Keel S, Chicka M, Brown AL, Kesserwan C, Agarwal A, Luo M, Li Z, Ross JE, Baliakas P, Pineda-Alvarez D, ... ... Godley LA, et al. ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants. Blood Advances. 3: 2962-2979. PMID 31648317 DOI: 10.1182/Bloodadvances.2019000644  0.355
2019 Godley LA. Inherited predisposition to myeloid malignancies. Blood Advances. 3: 2688. PMID 31506287 DOI: 10.1182/Bloodadvances.2019000172  0.333
2019 Godley LA. FouNdER mutations confer risk for leukemias. Blood. 133: 2636-2638. PMID 31221794 DOI: 10.1182/Blood-2019-04-901173  0.306
2019 Trottier AM, Cavalcante de Andrade Silva M, Li Z, Godley LA. Somatic mutation panels: Time to clear their names. Cancer Genetics. PMID 31101556 DOI: 10.1016/J.Cancergen.2019.04.065  0.37
2019 Jeong JJ, Gu X, Nie J, Sundaravel S, Liu H, Kuo WL, Bhagat TD, Pradhan K, Cao J, Nischal S, McGraw KL, Bhattacharyya S, Bishop MR, Artz A, Thirman MJ, ... ... Godley LA, et al. Cytokine regulated phosphorylation and activation of TET2 by JAK2 in hematopoiesis. Cancer Discovery. PMID 30944118 DOI: 10.1158/2159-8290.Cd-18-1138  0.376
2019 Trottier AM, Kraft IL, Druhan LJ, Lance A, Avalos BR, Godley LA. New Germline Syndrome Discovery: Heterozygous CSF3R Mutations May Predispose to Myeloid and Lymphoid Malignancies Blood. 134: 2543-2543. DOI: 10.1182/Blood-2019-129492  0.324
2019 Singhal D, Hahn CN, Moma LD, Wee LYA, Chhetri R, Babic M, Kutyna MM, Hiwase S, Parker WT, Feng J, Schreiber AW, Geoghegan J, Arts P, Gowda R, Singhal N, ... ... Godley LA, et al. Deleterious Germline Variants, Especially in the DNA Repair Pathway, Are Common in Patients with Non-Related Multiple Cancers, One of Them Being Hematological Malignancy Blood. 134: 1704-1704. DOI: 10.1182/Blood-2019-126462  0.36
2019 Kosuri S, Lee SM, Liu H, Mortel M, Godley LA, Larson RA, Odenike O, Stock W, Kline J, Riedell PA, Van Besien K, Bishop MR, Artz AS. Feasibility and Outcomes of T-Cell Depleted Hematopoietic Stem Cell Transplantation in Patients with Relapsed or Refractory AML and High Risk MDS Blood. 134: 3324-3324. DOI: 10.1182/Blood-2019-126211  0.306
2018 Obrochta E, Godley LA. Identifying patients with genetic predisposition to acute myeloid leukemia. Best Practice & Research. Clinical Haematology. 31: 373-378. PMID 30466750 DOI: 10.1016/J.Beha.2018.09.014  0.399
2018 Busque L, Godley LA. : guardian of the epigenetic galaxy. Blood. 132: 1468-1469. PMID 30287469 DOI: 10.1182/Blood-2018-08-867044  0.361
2018 D'Angelo CR, Novitsky B, Mee Lee S, Godley LA, Kline J, Larson RA, Liu H, Odenike O, Stock W, Bishop MR, Artz AS. Characterization of cancer comorbidity prior to allogeneic hematopoietic cell transplantation. Leukemia & Lymphoma. 1-10. PMID 30070150 DOI: 10.1080/10428194.2018.1493728  0.342
2018 Meisel M, Hinterleitner R, Pacis A, Chen L, Earley ZM, Mayassi T, Pierre JF, Ernest JD, Galipeau HJ, Thuille N, Bouziat R, Buscarlet M, Ringus DL, Wang Y, Li Y, ... ... Godley LA, et al. Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host. Nature. PMID 29769727 DOI: 10.1038/S41586-018-0125-Z  0.328
2018 Wei X, Calvo-Vidal MN, Chen S, Wu G, Revuelta MV, Sun J, Zhang J, Walsh MF, Nichols KE, Joseph V, Snyder C, Vachon CM, McKay JD, Wang SP, Jayabalan DS, ... ... Godley LA, et al. Germline mutations in lysine specific demethylase 1 (LSD1/KDM1A) confer susceptibility to multiple myeloma. Cancer Research. PMID 29559475 DOI: 10.1158/0008-5472.Can-17-1900  0.424
2018 Drazer MW, Kadri S, Sukhanova M, Patil SA, West AH, Feurstein S, Calderon DA, Jones MF, Weipert CM, Daugherty CK, Ceballos-López AA, Raca G, Lingen MW, Li Z, Segal JP, ... ... Godley LA, et al. Prognostic tumor sequencing panels frequently identify germ line variants associated with hereditary hematopoietic malignancies. Blood Advances. 2: 146-150. PMID 29365323 DOI: 10.1182/Bloodadvances.2017013037  0.337
2018 Wang AY, Weiner H, Green M, Chang H, Fulton N, Larson RA, Odenike O, Artz AS, Bishop MR, Godley LA, Thirman MJ, Kosuri S, Churpek JE, Curran E, Pettit K, et al. A phase I study of selinexor in combination with high-dose cytarabine and mitoxantrone for remission induction in patients with acute myeloid leukemia. Journal of Hematology & Oncology. 11: 4. PMID 29304833 DOI: 10.1186/S13045-017-0550-8  0.319
2018 Wang A, Weiner H, Larson RA, Odenike O, Artz AS, Bishop MR, Godley L, Thirman M, Kosuri S, Churpek J, Curran EK, Pettit K, Stock W, Liu H. Final Results from a Phase I Trial Combining Selinexor with High-Dose Cytarabine (HiDAC) and Mitoxantrone (Mito) for Remission Induction in Acute Myeloid Leukemia (AML) Blood. 132: 4073-4073. DOI: 10.1182/Blood-2018-99-120244  0.302
2018 Godley L, Luo X, Ross J, Jackson S, Agarwal A, Baliakas P, Bertuch AA, Brown AL, Chicka MC, DiNardo CD, Fleming MD, Keel S, Kesserwan C, Li Z, Luo M, et al. Myeloid Malignancy Variant Curation Expert Panel: An ASH-Sponsored Clingen Expert Panel to Optimize and Validate Acmg/AMP Variant Interpretation Guidelines for Genes Associated with Inherited Myeloid Neoplasms Blood. 132: 5849-5849. DOI: 10.1182/Blood-2018-99-118979  0.32
2017 Tsai SB, Rhodes J, Liu H, Shore T, Bishop M, Cushing MM, Gergis U, Godley L, Kline J, Larson RA, Mayer S, Odenike O, Stock W, Wickrema A, van Besien K, et al. Reduced Intensity Allogeneic Transplant for Acute Myeloid Leukemia and Myelodysplastic Syndrome Using Combined CD34-Selected Haploidentical Graft and a Single Umbilical Cord Unit Compared to Matched Unrelated Donor Stem Cells in Older Adults. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 29288821 DOI: 10.1016/J.Bbmt.2017.12.794  0.307
2017 Desai AV, Perpich M, Godley LA. Clinical Assessment and Diagnosis of Germline Predisposition to Hematopoietic Malignancies: The University of Chicago Experience. Frontiers in Pediatrics. 5: 252. PMID 29270394 DOI: 10.3389/Fped.2017.00252  0.331
2017 Godley LA. Mutant RUNX1 and histone tales. Blood. 130: 2156-2157. PMID 29146818 DOI: 10.1182/Blood-2017-09-805382  0.349
2017 Bhattacharyya S, Pradhan K, Campbell N, Mazdo J, Vasantkumar A, Maqbool S, Bhagat TD, Gupta S, Suzuki M, Yu Y, Greally JM, Steidl U, Bradner J, Dawlaty M, Godley L, et al. Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways. Genome Research. PMID 28986391 DOI: 10.1101/Gr.222794.117  0.395
2017 Brown AL, Churpek JE, Malcovati L, Döhner H, Godley LA. Recognition of familial myeloid neoplasia in adults. Seminars in Hematology. 54: 60-68. PMID 28637618 DOI: 10.1053/J.Seminhematol.2016.11.003  0.327
2017 Godley LA, Shimamura A. Genetic predisposition to hematologic malignancies: management and surveillance. Blood. PMID 28600339 DOI: 10.1182/Blood-2017-02-735290  0.32
2017 Feurstein S, Godley LA. Germline ETV6 mutations and predisposition to hematological malignancies. International Journal of Hematology. PMID 28555414 DOI: 10.1007/S12185-017-2259-4  0.372
2017 Godley LA. DNAJC21: the new kid on the SDS block. Blood. 129: 1413-1414. PMID 28302692 DOI: 10.1182/Blood-2017-01-761635  0.342
2017 Khan N, Hantel A, Knoebel RW, Artz A, Larson RA, Godley LA, Thirman MJ, Liu H, Churpek JE, King D, Odenike O, Stock W. Efficacy of single-agent decitabine in relapsed and refractory acute myeloid leukemia. Leukemia & Lymphoma. 1-7. PMID 28278716 DOI: 10.1080/10428194.2017.1289524  0.323
2017 Godley LA. Abstract IA15: Genetic predisposition to hematopoietic malignancies Genomics. 23. DOI: 10.1158/1557-3265.Hemmal17-Ia15  0.383
2016 Feurstein S, Drazer MW, Godley LA. Genetic predisposition to leukemia and other hematologic malignancies. Seminars in Oncology. 43: 598-608. PMID 27899193 DOI: 10.1053/J.Seminoncol.2016.10.003  0.31
2016 Applebaum MA, Jha AR, Kao C, Hernandez KM, DeWane G, Salwen HR, Chlenski A, Dobratic M, Mariani CJ, Godley LA, Prabhakar N, White K, Stranger BE, Cohn SL. Integrative genomics reveals hypoxia inducible genes that are associated with a poor prognosis in neuroblastoma patients. Oncotarget. PMID 27765905 DOI: 10.18632/Oncotarget.12713  0.387
2016 Rojek K, Nickels E, Neistadt B, Marquez R, Wickrema A, Artz A, van Besien K, Larson RA, Lee MK, Segal JP, King MC, Walsh T, Shimamura A, Keel SB, Churpek JE, ... Godley LA, et al. Identifying Inherited and Acquired Genetic Factors Involved in Poor Stem Cell Mobilization and Donor-Derived Malignancy. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 27497531 DOI: 10.1016/j.bbmt.2016.08.002  0.355
2016 DiNardo CD, Bannon SA, Routbort M, Franklin A, Mork M, Armanios M, Mace EM, Orange JS, Jeff-Eke M, Churpek JE, Takahashi K, Jorgensen JL, Garcia-Manero G, Kornblau S, Bertuch A, ... ... Godley LA, et al. Evaluation of Patients and Families With Concern for Predispositions to Hematologic Malignancies Within the Hereditary Hematologic Malignancy Clinic (HHMC). Clinical Lymphoma, Myeloma & Leukemia. PMID 27210295 DOI: 10.1016/J.Clml.2016.04.001  0.311
2016 Tsai SB, Liu H, Shore T, Fan Y, Bishop M, Cushing MM, Gergis U, Godley L, Kline J, Larson RA, Martinez G, Mayer S, Odenike O, Stock W, Wickrema A, et al. Frequency and Risk Factors Associated with Cord Graft Failure (CGF) after Transplant with Single Unit Umbilical Cord Cells Supplemented by Haploidentical Cells (Haplo-Cord) with Reduced-Intensity Conditioning. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 26912055 DOI: 10.1016/J.Bbmt.2016.02.010  0.312
2016 Schulze I, Rohde C, Scheller-Wendorff M, Bäumer N, Krause A, Herbst F, Riemke P, Hebestreit K, Tschanter P, Lin Q, Linhart H, Godley LA, Glimm H, Dugas M, Wagner W, et al. Increased DNA methylation of Dnmt3b targets impairs leukemogenesis. Blood. 127: 1575-86. PMID 26729896 DOI: 10.1182/Blood-2015-07-655928  0.443
2016 Leukam M, Kocherginsky M, Godley LA, Kline JP, Larson RA, Liu H, Odenike O, Stock W, Bishop MR, Artz AS. Evaluation of a pre-transplant serum biomarker score for allogeneic hematopoietic stem cell transplant (HCT) and association with clinical factors. Journal of Clinical Oncology. 34: e18537-e18537. DOI: 10.1200/Jco.2016.34.15_Suppl.E18537  0.303
2016 Liu H, Artz AS, Kocherginsky M, Larson RA, Odenike O, Kline JP, Godley LA, LaBelle JL, Stock W, Bishop MR. Feasibility of early withdrawal of immunosuppression (WOI) followed by dose escalation of prophylactic donor lymphocyte infusion (pDLI) after T-cell depleted (TCD) matched donor allogeneic hematopoietic cell transplantation (HCT). Journal of Clinical Oncology. 34: 7050-7050. DOI: 10.1200/Jco.2016.34.15_Suppl.7050  0.304
2016 D'Angelo CR, Novitsky B, Lee SM, Godley LA, Kline J, Larson RA, Liu H, Odenike O, Stock W, Bishop MR, Artz A. Comorbidity from Solid Tumor or Hematologic Malignancy Prior to Allogeneic Hematopoietic Cell Transplantation (HCT) May Both Increase Non-Relapse Mortality Blood. 128: 5844-5844. DOI: 10.1182/Blood.V128.22.5844.5844  0.352
2016 Wang AY, Weiner HL, Green M, Larson RA, Odenike O, Artz A, Godley LA, Thirman MJ, Churpek JE, Curran EK, Pettit K, Stock W, Liu H. Combination of Selinexor with High-Dose Cytarabine (HiDAC) and Mitoxantrone (Mito) for Remission Induction in Acute Myeloid Leukemia (AML) Is Feasible and Tolerable Blood. 128: 212-212. DOI: 10.1182/Blood.V128.22.212.212  0.327
2016 Brown AL, Hahn CN, Carmichael C, Wilkins E, Babic M, Chong C, Li X, Michaud J, Cannon P, Poplawski N, Altree M, Phillips K, Jaensch L, Fine M, Schreiber AW, ... ... Godley LA, et al. Expanded Phenotypic and Genetic Heterogeneity in the Clinical Spectrum of FPD-AML: Lymphoid Malignancies and Skin Disorders Are Common Features in Carriers of Germline RUNX1 Mutations Blood. 128: 1212-1212. DOI: 10.1182/Blood.V128.22.1212.1212  0.363
2016 Nath A, Wang F, Lenkala D, LaCroix B, Glavin N, Kipping-Johnson K, Geeleher P, Thirman M, Godley L, Raca G, Larson R, RSH. Abstract 2039: Exploring the longitudinal transcriptomic landscape of tyrosine kinase inhibitor treatment response in chronic myeloid leukemia patients Cancer Research. 76: 2039-2039. DOI: 10.1158/1538-7445.Am2016-2039  0.357
2016 Nath A, Wang F, Lenkala D, LaCroix B, Glavin N, Kipping-Johnson K, Geeleher P, Rich E, Thirman M, Godley L, Raca G, Larson R, Huang R. ID: 26: EXPLORING THE LONGITUDINAL TRANSCRIPTOMIC LANDSCAPE OF TYROSINE KINASE INHIBITOR TREATMENT RESPONSE IN CHRONIC MYELOID LEUKEMIA PATIENTS Journal of Investigative Medicine. 64: 935.2-936. DOI: 10.1136/Jim-2016-000120.50  0.35
2016 Drazer M, West A, Sukhanova M, Feurstein S, Jones M, Segal J, Churpeck J, Godley L. Somatic Next Generation Sequencing Panels Identify Potentially Pathogenic Germline Variants in Genes Associated with Hereditary Myeloid Malignancies Clinical Lymphoma, Myeloma & Leukemia. 16. DOI: 10.1016/J.Clml.2016.07.136  0.319
2015 Lewinsohn M, Brown AL, Weinel LM, Phung C, Rafidi G, Lee MK, Schreiber AW, Feng J, Babic M, Chong CE, Lee Y, Yong A, Suthers GK, Poplawski N, Altree M, ... ... Godley LA, et al. Novel germline DDX41 mutations define families with a lower age of MDS/AML onset, and lymphoid malignancies. Blood. PMID 26712909 DOI: 10.1182/Blood-2015-10-676098  0.353
2015 Laukka T, Mariani CJ, Ihantola T, Cao JZ, Hokkanen J, Kaelin WG, Godley LA, Koivunen P. Fumarate and Succinate Regulate Expression of Hypoxia-Inducible Genes via TET Enzymes. The Journal of Biological Chemistry. PMID 26703470 DOI: 10.1074/Jbc.M115.688762  0.421
2015 Vasanthakumar A, Arnovitz S, Marquez R, Lepore J, Rafidi G, Asom A, Weatherly M, Davis EM, Neistadt B, Duszynski R, Vardiman JW, Le Beau MM, Godley LA, Churpek JE. Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice. Blood. PMID 26644450 DOI: 10.1182/Blood-2015-03-635599  0.366
2015 Churpek JE, Marquez R, Neistadt B, Claussen K, Lee MK, Churpek MM, Huo D, Weiner H, Bannerjee M, Godley LA, Le Beau MM, Pritchard CC, Walsh T, King MC, Olopade OI, et al. Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia. Cancer. PMID 26641009 DOI: 10.1002/Cncr.29615  0.32
2015 Chapman CG, Mariani CJ, Wu F, Meckel K, Butun F, Chuang A, Madzo J, Bissonette MB, Kwon JH, Godley LA. TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer. Scientific Reports. 5: 17568. PMID 26631571 DOI: 10.1038/Srep17568  0.395
2015 Churpek JE, Pyrtel K, Kanchi KL, Shao J, Koboldt D, Miller CA, Shen D, Fulton R, O'Laughlin M, Fronick C, Pusic I, Uy GL, Braunstein EM, Levis M, Ross J, ... ... Godley LA, et al. Genomic analysis of germline and somatic variants in familial myelodysplasia/acute myeloid leukemia. Blood. PMID 26492932 DOI: 10.1182/Blood-2015-04-641100  0.363
2015 Vasanthakumar A, Zullow H, Lepore JB, Thomas K, Young N, Anastasi J, Reardon CA, Godley LA. Epigenetic Control of Apolipoprotein E Expression Mediates Gender-Specific Hematopoietic Regulation. Stem Cells (Dayton, Ohio). PMID 26417967 DOI: 10.1002/Stem.2214  0.402
2015 Dominguez PM, Teater M, Chambwe N, Kormaksson M, Redmond D, Ishii J, Vuong B, Chaudhuri J, Melnick A, Vasanthakumar A, Godley LA, Papavasiliou FN, Elemento O, Shaknovich R. DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID. Cell Reports. 12: 2086-98. PMID 26365193 DOI: 10.1016/J.Celrep.2015.08.036  0.394
2015 Moen EL, Litwin E, Arnovitz S, Zhang X, Zhang W, Dolan ME, Godley LA. Characterization of CpG sites that escape methylation on the inactive human X-chromosome. Epigenetics. 10: 810-8. PMID 26178744 DOI: 10.1080/15592294.2015.1069461  0.684
2015 Yamazaki J, Jelinek J, Lu Y, Cesaroni M, Madzo J, Neumann F, He R, Taby R, Vasanthakumar A, Macrae T, Ostler KR, Kantarjian HM, Liang S, Estecio MR, Godley LA, et al. TET2 mutations affect non-CpG island DNA methylation at enhancers and transcription factor binding sites in chronic myelomonocytic leukemia. Cancer Research. PMID 25972343 DOI: 10.1158/0008-5472.Can-14-0739  0.799
2015 Polprasert C, Schulze I, Sekeres MA, Makishima H, Przychodzen B, Hosono N, Singh J, Padgett RA, Gu X, Phillips JG, Clemente M, Parker Y, Lindner D, Dienes B, Jankowsky E, ... ... Godley LA, et al. Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms. Cancer Cell. 27: 658-70. PMID 25920683 DOI: 10.1016/J.Ccell.2015.03.017  0.368
2015 Vasanthakumar A, Godley LA. 5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy. Cancer Genetics. 208: 167-77. PMID 25892122 DOI: 10.1016/J.Cancergen.2015.02.009  0.349
2015 Brambert PR, Kelpsch DJ, Hameed R, Desai CV, Calafiore G, Godley LA, Raimondi SL. DNMT3B7 expression promotes tumor progression to a more aggressive phenotype in breast cancer cells. Plos One. 10: e0117310. PMID 25607950 DOI: 10.1371/Journal.Pone.0117310  0.392
2015 Zhang MY, Churpek JE, Keel SB, Walsh T, Lee MK, Loeb KR, Gulsuner S, Pritchard CC, Sanchez-Bonilla M, Delrow JJ, Basom RS, Forouhar M, Gyurkocza B, Schwartz BS, Neistadt B, ... ... Godley LA, et al. Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy. Nature Genetics. 47: 180-5. PMID 25581430 DOI: 10.1038/Ng.3177  0.391
2015 Moen EL, Mariani CJ, Zullow H, Jeff-Eke M, Litwin E, Nikitas JN, Godley LA. New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine. Immunological Reviews. 263: 36-49. PMID 25510270 DOI: 10.1111/Imr.12242  0.677
2015 Odenike O, Halpern A, Godley LA, Madzo J, Karrison T, Green M, Fulton N, Mattison RJ, Yee KW, Bennett M, Koval G, Malnassy G, Larson RA, Ratain MJ, Stock W. A phase I and pharmacodynamic study of the histone deacetylase inhibitor belinostat plus azacitidine in advanced myeloid neoplasia. Investigational New Drugs. 33: 371-9. PMID 25483416 DOI: 10.1007/S10637-014-0194-2  0.303
2015 Knight Johnson AE, Guidugli L, Arndt K, Alkorta-Aranburu G, Nelakuditi V, Churpek JE, Godley LA, del Gaudio D, Das S, Li Z. Identification of Genetic Hereditary Predisposition to Hematologic Malignancies By Clinical Next-Generation Sequencing Blood. 126: 3854-3854. DOI: 10.1182/Blood.V126.23.3854.3854  0.379
2015 Hantel A, Khan N, Larson RA, Godley LA, Thirman MJ, Artz A, Odenike O, Liu H, Churpek JE, King D, Rich E, Choi KJ, Knoebel RW, Stock W. Efficacy of Single-Agent Decitabine in Relapsed and Primary Refractory (rel/ref) Acute Myeloid Leukemia (AML) Blood. 126: 2518-2518. DOI: 10.1182/Blood.V126.23.2518.2518  0.33
2014 Rampal R, Alkalin A, Madzo J, Vasanthakumar A, Pronier E, Patel J, Li Y, Ahn J, Abdel-Wahab O, Shih A, Lu C, Ward PS, Tsai JJ, Hricik T, Tosello V, ... ... Godley LA, et al. DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia. Cell Reports. 9: 1841-55. PMID 25482556 DOI: 10.1016/J.Celrep.2014.11.004  0.425
2014 Godley LA. Inherited predisposition to acute myeloid leukemia. Seminars in Hematology. 51: 306-21. PMID 25311743 DOI: 10.1053/J.Seminhematol.2014.08.001  0.318
2014 Zhang X, Moen EL, Liu C, Mu W, Gamazon ER, Delaney SM, Wing C, Godley LA, Dolan ME, Zhang W. Linking the genetic architecture of cytosine modifications with human complex traits. Human Molecular Genetics. 23: 5893-905. PMID 24943591 DOI: 10.1093/Hmg/Ddu313  0.681
2014 Jasielec J, Saloura V, Godley LA. The mechanistic role of DNA methylation in myeloid leukemogenesis. Leukemia. 28: 1765-73. PMID 24913729 DOI: 10.1038/Leu.2014.163  0.408
2014 Mariani CJ, Vasanthakumar A, Madzo J, Yesilkanal A, Bhagat T, Yu Y, Bhattacharyya S, Wenger RH, Cohn SL, Nanduri J, Verma A, Prabhakar NR, Godley LA. TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma. Cell Reports. 7: 1343-52. PMID 24835990 DOI: 10.1016/J.Celrep.2014.04.040  0.337
2014 Vasanthakumar A, Godley LA. On the origin of leukemic species. Cell Stem Cell. 14: 421-2. PMID 24702991 DOI: 10.1016/J.Stem.2014.03.008  0.338
2014 Marquez R, Hantel A, Lorenz R, Neistadt B, Wong J, Churpek JE, Mardini NA, Shaukat I, Gurbuxani S, Miller JL, Godley LA. A new family with a germline ANKRD26 mutation and predisposition to myeloid malignancies. Leukemia & Lymphoma. 55: 2945-6. PMID 24628296 DOI: 10.3109/10428194.2014.903476  0.336
2014 Moen EL, Stark AL, Zhang W, Dolan ME, Godley LA. The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide. Molecular Cancer Therapeutics. 13: 1334-44. PMID 24568970 DOI: 10.1158/1535-7163.Mct-13-0924  0.71
2014 West AH, Godley LA, Churpek JE. Familial myelodysplastic syndrome/acute leukemia syndromes: a review and utility for translational investigations. Annals of the New York Academy of Sciences. 1310: 111-8. PMID 24467820 DOI: 10.1111/Nyas.12346  0.325
2014 Chambwe N, Kormaksson M, Geng H, De S, Michor F, Johnson NA, Morin RD, Scott DW, Godley LA, Gascoyne RD, Melnick A, Campagne F, Shaknovich R. Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes. Blood. 123: 1699-708. PMID 24385541 DOI: 10.1182/Blood-2013-07-509885  0.397
2014 Madzo J, Liu H, Rodriguez A, Vasanthakumar A, Sundaravel S, Caces DB, Looney TJ, Zhang L, Lepore JB, Macrae T, Duszynski R, Shih AH, Song CX, Yu M, Yu Y, ... ... Godley LA, et al. Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis. Cell Reports. 6: 231-44. PMID 24373966 DOI: 10.1016/J.Celrep.2013.11.044  0.363
2014 Jeong M, Sun D, Luo M, Huang Y, Challen GA, Rodriguez B, Zhang X, Chavez L, Wang H, Hannah R, Kim SB, Yang L, Ko M, Chen R, Göttgens B, ... ... Godley LA, et al. Large conserved domains of low DNA methylation maintained by Dnmt3a. Nature Genetics. 46: 17-23. PMID 24270360 DOI: 10.1038/Ng.2836  0.442
2014 Tsai SB, Liu H, Shore TB, Bishop MR, Cushing MM, Fan Y, Gergis U, Godley LA, Kline J, Larson RA, Martinez GG, Mayer S, Odenike O, Stock W, Wickrema A, et al. Frequency and Risk Factors of Cord Graft Failure (CGF) Following Reduced Intensity Conditioning Haplo-Cord Hematopoietic Stem Cell Transplantation Blood. 124: 2463-2463. DOI: 10.1182/Blood.V124.21.2463.2463  0.3
2014 Rhodes J, van Besien K, Liu H, Gergis U, Tsai SB, Mayer S, Stock W, Larson RA, Shore TB, Odenike O, Pearse R, Godley LA, Mark TM, Kline J, Bishop MR, et al. Haplo-Cord Transplantation Vs Unrelated Donor Stem Cell Transplantation in Patients with AML/MDS Older Than 50 Blood. 124: 1235-1235. DOI: 10.1182/Blood.V124.21.1235.1235  0.305
2014 van Besien K, Liu H, Gergis U, Cushing MM, Tsai S, Mayer S, Wickrema A, Stock W, Larson RA, Shore TB, Odenike O, Pearse RN, Godley LA, Mark TM, Kline J, et al. Haplo-Cord UCB SCT with Low Cell Dose, Well Matched UCB Units. a Prospective Multicenter Study Blood. 124: 1093-1093. DOI: 10.1182/Blood.V124.21.1093.1093  0.309
2014 Moen EL, Stark AL, Zhang W, Dolan ME, Godley LA. Abstract 5461: The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide Cancer Research. 74: 5461-5461. DOI: 10.1158/1538-7445.Am2014-5461  0.439
2013 Mariani CJ, Madzo J, Moen EL, Yesilkanal A, Godley LA. Alterations of 5-hydroxymethylcytosine in human cancers. Cancers. 5: 786-814. PMID 24202321 DOI: 10.3390/Cancers5030786  0.672
2013 Clozel T, Yang S, Elstrom RL, Tam W, Martin P, Kormaksson M, Banerjee S, Vasanthakumar A, Culjkovic B, Scott DW, Wyman S, Leser M, Shaknovich R, Chadburn A, Tabbo F, ... Godley LA, et al. Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma. Cancer Discovery. 3: 1002-19. PMID 23955273 DOI: 10.1158/2159-8290.Cd-13-0117  0.411
2013 Nickels EM, Soodalter J, Churpek JE, Godley LA. Recognizing familial myeloid leukemia in adults. Therapeutic Advances in Hematology. 4: 254-69. PMID 23926458 DOI: 10.1177/2040620713487399  0.32
2013 Bhattacharyya S, Yu Y, Suzuki M, Campbell N, Mazdo J, Vasanthakumar A, Bhagat TD, Nischal S, Christopeit M, Parekh S, Steidl U, Godley L, Maitra A, Greally JM, Verma A. Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer. Nucleic Acids Research. 41: e157. PMID 23861445 DOI: 10.1093/Nar/Gkt601  0.382
2013 Moen EL, Zhang X, Mu W, Delaney SM, Wing C, McQuade J, Myers J, Godley LA, Dolan ME, Zhang W. Genome-wide variation of cytosine modifications between European and African populations and the implications for complex traits. Genetics. 194: 987-96. PMID 23792949 DOI: 10.1534/Genetics.113.151381  0.673
2013 Goodell MA, Godley LA. Perspectives and future directions for epigenetics in hematology. Blood. 121: 5131-7. PMID 23692857 DOI: 10.1182/Blood-2013-04-427724  0.373
2013 Madzo J, Vasanthakumar A, Godley LA. Perturbations of 5-hydroxymethylcytosine patterning in hematologic malignancies. Seminars in Hematology. 50: 61-9. PMID 23507484 DOI: 10.1053/J.Seminhematol.2013.01.004  0.353
2013 Lu Z, Tian Y, Salwen HR, Chlenski A, Godley LA, Raj JU, Yang Q. Histone-lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, cell invasion, and DNA methylation of human neuroblastoma cells. Anti-Cancer Drugs. 24: 484-93. PMID 23466651 DOI: 10.1097/Cad.0B013E32835Ffdbb  0.403
2013 Vasanthakumar A, Lepore JB, Zegarek MH, Kocherginsky M, Singh M, Davis EM, Link PA, Anastasi J, Le Beau MM, Karpf AR, Godley LA. Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis. Blood. 121: 2059-63. PMID 23315164 DOI: 10.1182/Blood-2012-04-421065  0.413
2013 Yu Y, Mo Y, Ebenezer D, Bhattacharyya S, Liu H, Sundaravel S, Giricz O, Wontakal S, Cartier J, Caces B, Artz A, Nischal S, Bhagat T, Bathon K, Maqbool S, ... ... Godley L, et al. High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis. The Journal of Biological Chemistry. 288: 8805-14. PMID 23306203 DOI: 10.1074/Jbc.M112.423756  0.408
2013 Jain N, Liu H, Artz AS, Anastasi J, Odenike O, Godley LA, Joseph L, Marino S, Kline J, Nguyen V, Schouten V, Kunnavakkam R, Larson RA, Stock W, Ulaszek J, et al. Immune reconstitution after combined haploidentical and umbilical cord blood transplant. Leukemia & Lymphoma. 54: 1242-9. PMID 23088744 DOI: 10.3109/10428194.2012.739688  0.319
2013 Pollyea DA, Kohrt HE, Zhang B, Zehnder J, Schenkein D, Fantin V, Straley K, Vasanthakumar A, Abdel-Wahab O, Levine R, Godley LA, Medeiros BC. 2-Hydroxyglutarate in IDH mutant acute myeloid leukemia: predicting patient responses, minimal residual disease and correlations with methylcytosine and hydroxymethylcytosine levels. Leukemia & Lymphoma. 54: 408-10. PMID 22680765 DOI: 10.3109/10428194.2012.701009  0.392
2013 Jeong M, Sun D, Luo M, Huang Y, Ko M, Chavez L, Challen GA, Rodriguez B, Zhang X, Yang L, Wang H, Chen R, Hannah R, Kim S, Lee J, ... ... Godley LA, et al. Large Conserved Domains Of Low DNA Methylation Maintained By 5-Hydroxymethycytosine and Dnmt3a Blood. 122: 2406-2406. DOI: 10.1182/Blood.V122.21.2406.2406  0.466
2013 Ustun C, Reiter A, Scott BL, Nakamura R, Gandhi D, Kreil S, Shanley R, Hogan WJ, Perales M, Shore TB, Baurmann H, Stuart RK, Gruhn B, Doubek M, Hsu JW, ... ... Godley LA, et al. Allogeneic Hematopoietic Cell Transplantation Is Effective In Patients With Advanced Systemic Mastocytosis: A Multicenter Retrospective Analysis Blood. 122: 2145-2145. DOI: 10.1182/Blood.V122.21.2145.2145  0.364
2013 Vasanthakumar A, Zullow H, Godley LA. Hematopoietic Stem Cell Function Is Regulated By Hormonal and Epigenetic Factors Blood. 122: 1194-1194. DOI: 10.1182/Blood.V122.21.1194.1194  0.391
2013 Bhattacharyya S, Yu Y, Suzuki M, Cambpell N, Mazdo J, Vasantkumar A, Bhagat TD, Nischal S, Steidl U, Godley L, Maitra A, Greally JM, Verma A. Abstract 4231: Genome wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer. Cancer Research. 73: 4231-4231. DOI: 10.1158/1538-7445.Am2013-4231  0.393
2013 Moen EL, Mu W, Godley LA, Dolan ME, Zhang W. Abstract 2216: The role of cytosine modifications in cellular sensitivity to cytarabine. Cancer Research. 73: 2216-2216. DOI: 10.1158/1538-7445.Am2013-2216  0.372
2012 Moen EL, Godley LA, Zhang W, Dolan ME. Pharmacogenomics of chemotherapeutic susceptibility and toxicity. Genome Medicine. 4: 90. PMID 23199206 DOI: 10.1186/Gm391  0.663
2012 Busque L, Patel JP, Figueroa ME, Vasanthakumar A, Provost S, Hamilou Z, Mollica L, Li J, Viale A, Heguy A, Hassimi M, Socci N, Bhatt PK, Gonen M, Mason CE, ... ... Godley LA, et al. Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis. Nature Genetics. 44: 1179-81. PMID 23001125 DOI: 10.1038/Ng.2413  0.398
2012 Ostler KR, Yang Q, Looney TJ, Zhang L, Vasanthakumar A, Tian Y, Kocherginsky M, Raimondi SL, DeMaio JG, Salwen HR, Gu S, Chlenski A, Naranjo A, Gill A, Peddinti R, ... ... Godley LA, et al. Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma. Cancer Research. 72: 4714-23. PMID 22815530 DOI: 10.1158/0008-5472.Can-12-0886  0.801
2012 Godley LA. Profiles in leukemia. The New England Journal of Medicine. 366: 1152-3. PMID 22417205 DOI: 10.1056/Nejme1200409  0.367
2012 Godley LA, Le Beau MM. The histone code and treatments for acute myeloid leukemia. The New England Journal of Medicine. 366: 960-1. PMID 22397660 DOI: 10.1056/Nejmcibr1113401  0.363
2012 Yamazaki J, Taby R, Vasanthakumar A, Macrae T, Ostler KR, Shen L, Kantarjian HM, Estecio MR, Jelinek J, Godley LA, Issa JP. Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia. Epigenetics. 7: 201-7. PMID 22395470 DOI: 10.4161/Epi.7.2.19015  0.801
2012 Nanduri J, Makarenko V, Reddy VD, Yuan G, Pawar A, Wang N, Khan SA, Zhang X, Kinsman B, Peng YJ, Kumar GK, Fox AP, Godley LA, Semenza GL, Prabhakar NR. Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 109: 2515-20. PMID 22232674 DOI: 10.1073/Pnas.1120600109  0.343
2012 Challen GA, Sun D, Jeong M, Luo M, Jelinek J, Berg JS, Bock C, Vasanthakumar A, Gu H, Xi Y, Liang S, Lu Y, Darlington GJ, Meissner A, Issa JP, ... Godley LA, et al. Dnmt3a is essential for hematopoietic stem cell differentiation. Nature Genetics. 44: 23-31. PMID 22138693 DOI: 10.1038/Ng.1009  0.377
2012 Doçi CL, Mankame TP, Langerman A, Ostler KR, Kanteti R, Best T, Onel K, Godley LA, Salgia R, Lingen MW. Characterization of NOL7 gene point mutations, promoter methylation, and protein expression in cervical cancer. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. 31: 15-24. PMID 22123719 DOI: 10.1097/Pgp.0B013E318220Ba16  0.802
2012 van Besien K, Stock W, Rich E, Odenike O, Godley LA, O'Donnell PH, Kline J, Nguyen V, Del Cerro P, Larson RA, Artz AS. Phase I-II study of clofarabine-melphalan-alemtuzumab conditioning for allogeneic hematopoietic cell transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 18: 913-21. PMID 22079470 DOI: 10.1016/J.Bbmt.2011.10.041  0.303
2012 Larson SM, Campbell NP, Huo D, Artz A, Zhang Y, Gajria D, Green M, Weiner H, Daugherty C, Odenike O, Godley LA, Hyjek E, Gurbuxani S, Thirman M, Sipkins D, et al. High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML). Leukemia & Lymphoma. 53: 445-50. PMID 21913806 DOI: 10.3109/10428194.2011.621562  0.31
2012 Halpern AB, Kunnavakkum R, Joseph L, Stock W, Odenike O, Godley LA, Thirman MJ, Artz AS, Sipkins D, Liu H, Raca G, Le Beau MM, Larson RA. Single center experience treating adults with FLT3-mutated acute myeloid leukemia (AML). Journal of Clinical Oncology. 30: 6562-6562. DOI: 10.1200/Jco.2012.30.15_Suppl.6562  0.356
2012 Ruiz MA, Vaitkus K, Vasanthakumar A, Rivers A, Kouznetsova T, DeSimone J, Godley LA, Lavelle D. Dynamic Regulation of 5-Hydroxymethylcytosine At the γ-Globin Promoter During Erythroid Differentiation Blood. 120: 824-824. DOI: 10.1182/Blood.V120.21.824.824  0.373
2012 Moen EL, Mu W, Delaney SM, Wing C, Godley LA, Dolan ME, Zhang W. Abstract 5010: Differences in DNA methylation between the African and European HapMap populations Cancer Research. 72: 5010-5010. DOI: 10.1158/1538-7445.Am2012-5010  0.413
2012 Brambert PR, Rehbein J, Slezak I, Kelpsch DJ, Ostler KR, Godley LA, Raimondi SL. Abstract 1053: DNMT3B7 alters E-cadherin expression and cell proliferation in breast cancer cells Cancer Research. 72: 1053-1053. DOI: 10.1158/1538-7445.Am2012-1053  0.791
2012 Ostler KR, Yang Q, Vasanthakumar A, Zhang L, Looney TJ, Naranjo A, Salwen H, Kocherginsky M, Lahn BT, Cohn SL, Godley LA. Abstract 1040: A truncated DNMT3B protein (DNMT3B7) drives DNA methylation and suppresses growth in human neuroblastoma Cancer Research. 72: 1040-1040. DOI: 10.1158/1538-7445.Am2012-1040  0.806
2011 Szulwach KE, Li X, Li Y, Song CX, Wu H, Dai Q, Irier H, Upadhyay AK, Gearing M, Levey AI, Vasanthakumar A, Godley LA, Chang Q, Cheng X, He C, et al. 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nature Neuroscience. 14: 1607-16. PMID 22037496 DOI: 10.1038/Nn.2959  0.389
2011 Liu H, Rich ES, Godley L, Odenike O, Joseph L, Marino S, Kline J, Nguyen V, Cunningham J, Larson RA, del Cerro P, Schroeder L, Pape L, Stock W, Wickrema A, et al. Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions. Blood. 118: 6438-45. PMID 21976674 DOI: 10.1182/Blood-2011-08-372508  0.317
2011 Shaknovich R, Cerchietti L, Tsikitas L, Kormaksson M, De S, Figueroa ME, Ballon G, Yang SN, Weinhold N, Reimers M, Clozel T, Luttrop K, Ekstrom TJ, Frank J, Vasanthakumar A, ... Godley LA, et al. DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation. Blood. 118: 3559-69. PMID 21828137 DOI: 10.1182/Blood-2011-06-357996  0.395
2011 Pronier E, Almire C, Mokrani H, Vasanthakumar A, Simon A, da Costa Reis Monte Mor B, Massé A, Le Couédic JP, Pendino F, Carbonne B, Larghero J, Ravanat JL, Casadevall N, Bernard OA, Droin N, ... ... Godley LA, et al. Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors. Blood. 118: 2551-5. PMID 21734233 DOI: 10.1182/Blood-2010-12-324707  0.416
2011 Quivoron C, Couronné L, Della Valle V, Lopez CK, Plo I, Wagner-Ballon O, Do Cruzeiro M, Delhommeau F, Arnulf B, Stern MH, Godley L, Opolon P, Tilly H, Solary E, Duffourd Y, et al. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell. 20: 25-38. PMID 21723201 DOI: 10.1016/J.Ccr.2011.06.003  0.407
2011 Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye-Lobry D, Lobry C, Figueroa ME, Vasanthakumar A, Patel J, Zhao X, Perna F, Pandey S, Madzo J, Song C, Dai Q, ... ... Godley LA, et al. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell. 20: 11-24. PMID 21723200 DOI: 10.1016/J.Ccr.2011.06.001  0.352
2011 Godley LA, Cunningham J, Dolan ME, Huang RS, Gurbuxani S, McNerney ME, Larson RA, Leong H, Lussier Y, Onel K, Odenike O, Stock W, White KP, Le Beau MM. An integrated genomic approach to the assessment and treatment of acute myeloid leukemia. Seminars in Oncology. 38: 215-24. PMID 21421111 DOI: 10.1053/J.Seminoncol.2011.01.003  0.382
2011 Odenike O, Thirman MJ, Artz AS, Godley LA, Larson RA, Stock W. Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet? Seminars in Oncology. 38: 196-214. PMID 21421110 DOI: 10.1053/J.Seminoncol.2011.01.010  0.383
2011 Godley LA, Mondragón A. Molecular biology. Preference by exclusion. Science (New York, N.Y.). 331: 1017-8. PMID 21350155 DOI: 10.1126/Science.1202090  0.383
2011 Woloszynska-Read A, Zhang W, Yu J, Link PA, Mhawech-Fauceglia P, Collamat G, Akers SN, Ostler KR, Godley LA, Odunsi K, Karpf AR. Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 2170-80. PMID 21296871 DOI: 10.1158/1078-0432.Ccr-10-2315  0.778
2011 Levis M, Ravandi F, Wang ES, Baer MR, Perl A, Coutre S, Erba H, Stuart RK, Baccarani M, Cripe LD, Tallman MS, Meloni G, Godley LA, Langston AA, Amadori S, et al. Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse. Blood. 117: 3294-301. PMID 21270442 DOI: 10.1182/Blood-2010-08-301796  0.313
2011 Song CX, Szulwach KE, Fu Y, Dai Q, Yi C, Li X, Li Y, Chen CH, Zhang W, Jian X, Wang J, Zhang L, Looney TJ, Zhang B, Godley LA, et al. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nature Biotechnology. 29: 68-72. PMID 21151123 DOI: 10.1038/Nbt.1732  0.353
2011 Kenkre VP, Horowitz S, Artz AS, Liao C, Cohen KS, Godley LA, Kline JP, Smith SM, Stock W, van Besien K. T-cell-depleted allogeneic transplant without donor leukocyte infusions results in excellent long-term survival in patients with multiply relapsed Lymphoma. Predictors for survival after transplant relapse. Leukemia & Lymphoma. 52: 214-22. PMID 21142785 DOI: 10.3109/10428194.2010.538777  0.308
2011 Liu H, Rich ES, Godley L, Odenike O, Joseph L, Marino S, Kline J, Nguyen VH, Cunningham JM, Larson RA, Cerro PD, Schroeder L, Pape L, Stock W, Wickrema A, et al. Reduced Intensity Conditioning with Combined Haploidentical and Cord Blood Transplantation Results in Rapid Engraftment and Durable Remissions in Hematological Malignancies Blood. 118: 830-830. DOI: 10.1182/Blood.V118.21.830.830  0.303
2011 Pollyea DA, Kohrt HE, Zhang B, Zehnder JL, Schenkein DP, Fantin V, Straley K, Vasanthakumar A, Abdel-Wahab O, Levine RL, Godley L, Medeiros BC. 2-Hydroxyglutarate in IDH mutant AML: Predicting Patient Responses, Minimal Residual Disease and Correlations with Methylcytosine and Hydroxymethylcytosine Levels Blood. 118: 2509-2509. DOI: 10.1182/Blood.V118.21.2509.2509  0.364
2011 Vasanthakumar A, Lepore JB, Zegarek MH, Kocherginsky M, Singh M, Godley LA. Myc -Mediated Lymphomagenesis Is Driven by DNA Methylation Changes Induced by DNMT3B7 Expression and Dnmt3b Heterozygosity Blood. 118: 225-225. DOI: 10.1182/Blood.V118.21.225.225  0.446
2011 Van Besien KM, Stock W, Rich ES, Odenike O, Godley L, O'Donnell P, Kline J, Nguyen VH, Cerro PD, Larson RA, Artz A. Clofarabine-Melphalan-Alemtuzumab Conditioning for Allogeneic Hematopoietic Cell Transplantation: Final Report of a Phase I-II Study Blood. 118: 1948-1948. DOI: 10.1182/Blood.V118.21.1948.1948  0.311
2011 Clozel T, Yang S, Kormaksson M, Elstrom R, Vasanthakumar A, Brennan S, Culjkovic B, Leser M, Martin P, Borden KL, Wang YL, Cheng S, Tam W, Shaknovich R, Chadburn A, ... Godley L, et al. Chemosensitization of Diffuse Large B Cell Lymphoma by Demethylating Nucleoside Analogues Blood. 118: 1617-1617. DOI: 10.1182/Blood.V118.21.1617.1617  0.421
2011 Yamazaki J, Taby RF, Vasanthakumar A, Macrae T, Ostler KR, Shen L, Kantarjian HM, Estecio MR, Jelinek J, Godley L, Issa J. Limited Effect of TET2 Mutations on Promoter DNA Methylation in Chronic Myelomonocytic Leukemia Blood. 118: 1365-1365. DOI: 10.1182/Blood.V118.21.1365.1365  0.803
2010 Larson SM, Godley LA. Getting to the root of the stem cell in mutated chronic myeloid leukemia. Leukemia & Lymphoma. 51: 2147-8. PMID 21133735 DOI: 10.3109/10428194.2010.531802  0.345
2010 Figueroa ME, Abdel-Wahab O, Lu C, Ward PS, Patel J, Shih A, Li Y, Bhagwat N, Vasanthakumar A, Fernandez HF, Tallman MS, Sun Z, Wolniak K, Peeters JK, Liu W, ... ... Godley LA, et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell. 18: 553-67. PMID 21130701 DOI: 10.1016/J.Ccr.2010.11.015  0.439
2010 Smith SM, Anastasi J, Cohen KS, Godley LA. The impact of MYC expression in lymphoma biology: beyond Burkitt lymphoma. Blood Cells, Molecules & Diseases. 45: 317-23. PMID 20817505 DOI: 10.1016/J.Bcmd.2010.08.002  0.354
2010 Garcia JS, Jain N, Godley LA. An update on the safety and efficacy of decitabine in the treatment of myelodysplastic syndromes. Oncotargets and Therapy. 3: 1-13. PMID 20616953 DOI: 10.2147/Ott.S7222  0.347
2010 Shah MY, Vasanthakumar A, Barnes NY, Figueroa ME, Kamp A, Hendrick C, Ostler KR, Davis EM, Lin S, Anastasi J, Le Beau MM, Moskowitz IP, Melnick A, Pytel P, Godley LA. DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis. Cancer Research. 70: 5840-50. PMID 20587527 DOI: 10.1158/0008-5472.CAN-10-0847  0.793
2010 Yang Q, Tian Y, Ostler KR, Chlenski A, Guerrero LJ, Salwen HR, Godley LA, Cohn SL. Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines. Bmc Cancer. 10: 286. PMID 20546602 DOI: 10.1186/1471-2407-10-286  0.791
2010 Godley LA, Njiaju UO, Green M, Weiner H, Lin S, Odenike O, Rich ES, Artz A, Van Besien K, Daugherty CK, Zhang Y, Le Beau MM, Stock W, Larson RA. Treatment of therapy-related myeloid neoplasms with high-dose cytarabine/mitoxantrone followed by hematopoietic stem cell transplant. Leukemia & Lymphoma. 51: 995-1006. PMID 20536346 DOI: 10.3109/10428191003763468  0.308
2010 Locke FL, Artz AS, Godley LA, Odenike O, Larson RA, Van Besien K, Stock W. A prospective feasibility study of clofarabine (CLO) cytoreduction prior to allogeneic stem cell transplant (HCT) conditioning for refractory leukemia and MDS. Journal of Clinical Oncology. 28: 6537-6537. DOI: 10.1200/Jco.2010.28.15_Suppl.6537  0.311
2010 Garcia JS, Madzo J, Cooper D, Jackson SA, Onel K, Larson RA, Artz A, Godley LA. Pre-Donor Evaluation of an HLA Matched Sibling Identifies a Novel Inherited RUNX1 Mutation Encoding a Missense Mutation Found Outside of the RUNT Domain in Familial Platelet Disorder Blood. 116: 2709-2709. DOI: 10.1182/Blood.V116.21.2709.2709  0.407
2009 Poiré X, Artz A, Larson RA, Kline J, Odenike O, Rich E, Godley L, Stock W, van Besien K. Allogeneic stem cell transplantation with alemtuzumab-based conditioning for patients with advanced chronic myelogenous leukemia. Leukemia & Lymphoma. 50: 85-91. PMID 19142796 DOI: 10.1080/10428190802626624  0.322
2009 Shah M, Vasanthakumar A, Barnes N, Godley LA. Expression of a Truncated DNMT3B Protein, DNMT3B7, Highlights the Sensitivity of Hematopoietic Progenitor Cell Function to Hormonal Milieu. Blood. 114: 83-83. DOI: 10.1182/Blood.V114.22.83.83  0.434
2009 Levis M, Ravandi F, Wang ES, Baer MR, Perl A, Coutre S, Erba H, Stuart RK, Baccarani M, Cripe LD, Tallman MS, Meloni G, Godley LA, Langston AA, Amadori S, et al. Results From a Randomized Trial of Salvage Chemotherapy Followed by Lestaurtinib for FLT3 Mutant AML Patients in First Relapse. Blood. 114: 788-788. DOI: 10.1182/Blood.V114.22.788.788  0.317
2009 Churpek JE, Garcia JS, Madzo J, Jackson S, Onel K, Godley LA. Molecular Characterization of a Novel 3' Mutation in RUNX1 in a New Pedigree with Familial Platelet Disorder. Blood. 114: 1626-1626. DOI: 10.1182/Blood.V114.22.1626.1626  0.386
2009 Larson S, Campbell N, Huo D, Artz A, Zhang Y, Gajria D, Green M, Rahimova G, Weiner H, Torres M, Odenike O, Godley LA, Rich ES, Thirman M, Larson RA, et al. High Dose Cytarabine (HiDAC) and Mitoxantrone (MITO) Is An Effective Induction Therapy for High-Risk Acute Myeloid Leukemia (AML). Blood. 114: 1048-1048. DOI: 10.1182/Blood.V114.22.1048.1048  0.305
2009 Godley LA, Njiaju UO, Green M, Weiner H, Lin S, Odenike O, Rich ES, Artz A, van Besien K, Daugherty C, Zhang Y, Le Beau MM, Stock W, Larson RA. Treatment of Therapy-Related Myeloid Neoplasms with High-Dose Cytarabine/Mitoxantrone Followed by Hematopoietic Cell Transplantation (HCT). Blood. 114: 1030-1030. DOI: 10.1182/Blood.V114.22.1030.1030  0.312
2008 Godley LA, Steensma DP, Baer MR, Slack JL, Buckstein R, Larsen JS, Arora S, Cullen MT, Kantarjian HM. Cytogenetic responses to a 5-day dosing schedule of decitabine in patients (Pts) with myelodysplastic syndromes (MDS). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 7030. PMID 27950013 DOI: 10.1200/Jco.2008.26.15_Suppl.7030  0.309
2008 Fackenthal JD, Godley LA. Aberrant RNA splicing and its functional consequences in cancer cells. Disease Models & Mechanisms. 1: 37-42. PMID 19048051 DOI: 10.1242/Dmm.000331  0.389
2008 Artz AS, Wickrema A, Dinner S, Godley LA, Kocherginsky M, Odenike O, Rich ES, Stock W, Ulaszek J, Larson RA, van Besien K. Pretreatment C-reactive protein is a predictor for outcomes after reduced-intensity allogeneic hematopoietic cell transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 14: 1209-16. PMID 18940674 DOI: 10.1016/J.Bbmt.2008.08.004  0.307
2008 Carbonaro A, Mohanty SK, Huang H, Godley LA, Sohn LL. Cell characterization using a protein-functionalized pore Lab On a Chip - Miniaturisation For Chemistry and Biology. 8: 1478-1485. PMID 18818802 DOI: 10.1039/B801929K  0.303
2008 Ozer O, Zhao YD, Ostler KR, Akin C, Anastasi J, Vardiman JW, Godley LA. The identification and characterisation of novel KIT transcripts in aggressive mast cell malignancies and normal CD34+ cells. Leukemia & Lymphoma. 49: 1567-77. PMID 18766971 DOI: 10.1080/10428190802140865  0.792
2008 Godley LA, Larson RA. Therapy-related myeloid leukemia. Seminars in Oncology. 35: 418-29. PMID 18692692 DOI: 10.1053/J.Seminoncol.2008.04.012  0.308
2008 Klisovic RB, Stock W, Cataland S, Klisovic MI, Liu S, Blum W, Green M, Odenike O, Godley L, Burgt JV, Van Laar E, Cullen M, Macleod AR, Besterman JM, Reid GK, et al. A phase I biological study of MG98, an oligodeoxynucleotide antisense to DNA methyltransferase 1, in patients with high-risk myelodysplasia and acute myeloid leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 2444-9. PMID 18413836 DOI: 10.1158/1078-0432.Ccr-07-1320  0.394
2008 Gordon MK, Sher D, Karrison T, Kebriaei P, Chuang K, Zhang Y, McDonnell D, Artz A, Godley L, Odenike O, Rich E, Michaelis L, Thirman MJ, Wickrema A, van Besien K, et al. Successful autologous stem cell collection in patients with chronic myeloid leukemia in complete cytogenetic response, with quantitative measurement of BCR-ABL expression in blood, marrow, and apheresis products. Leukemia & Lymphoma. 49: 531-7. PMID 18297531 DOI: 10.1080/10428190701799043  0.353
2007 Mattison RJ, Ostler KR, Locke FL, Godley LA. Implications of FLT3 mutations in the therapy of acute myeloid leukemia. Reviews On Recent Clinical Trials. 2: 135-41. PMID 18473998 DOI: 10.2174/157488707780599320  0.781
2007 Pollyea DA, Artz AS, Stock W, Daugherty C, Godley L, Odenike OM, Rich E, Smith SM, Zimmerman T, Zhang Y, Huo D, Larson R, van Besien K. Outcomes of patients with AML and MDS who relapse or progress after reduced intensity allogeneic hematopoietic cell transplantation. Bone Marrow Transplantation. 40: 1027-32. PMID 17846595 DOI: 10.1038/Sj.Bmt.1705852  0.328
2007 Kihslinger JE, Godley LA. The use of hypomethylating agents in the treatment of hematologic malignancies. Leukemia & Lymphoma. 48: 1676-95. PMID 17786703 DOI: 10.1080/10428190701493910  0.376
2007 Ostler KR, Davis EM, Payne SL, Gosalia BB, Expósito-Céspedes J, Le Beau MM, Godley LA. Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins. Oncogene. 26: 5553-63. PMID 17353906 DOI: 10.1038/Sj.Onc.1210351  0.811
2007 Ozer O, Zhao YD, Ostler KR, Akin C, Anastasi J, Vardiman J, Godley L. Novel C-KIT Transcripts Identified in Mast Cell Leukemia: An Update of the Full Transcript and It’s Distribution. Blood. 110: 2396-2396. DOI: 10.1182/Blood.V110.11.2396.2396  0.785
2007 Donepudi S, Mattison RJ, Kihslinger JE, Godley LA. Modulators of DNA methylation and histone acetylation Update On Cancer Therapeutics. 2: 157-169. DOI: 10.1016/J.Uct.2007.10.004  0.399
2006 Pollyea DA, Artz AS, Stock W, Daugherty C, Godley L, Odenike OM, Rich E, Smith SM, Zimmerman T, Zhang Y, Huo D, Larson R, Van Besien K. New Cytogenetic Abnormalities Are Frequent in AML and MDS Relapsing after Allogeneic Hematopoietic Cell Transplantation (HCT). Blood. 108: 3675-3675. DOI: 10.1182/Blood.V108.11.3675.3675  0.305
2005 van Besien K, Artz A, Smith S, Cao D, Rich S, Godley L, Jones D, Del Cerro P, Bennett D, Casey B, Odenike O, Thirman M, Daugherty C, Wickrema A, Zimmerman T, et al. Fludarabine, melphalan, and alemtuzumab conditioning in adults with standard-risk advanced acute myeloid leukemia and myelodysplastic syndrome. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 5728-38. PMID 16009946 DOI: 10.1200/Jco.2005.15.602  0.305
2005 Pollyea DA, Artz AS, Stock W, Godley L, Odenike OM, Rich E, Smith SM, Larson R, Van Besien K. Leukemic Relapse after Allogeneic Stem Cell Transplantation with a T-Cell Depleted Reduced Intensity Conditioning (RIST) Regimen. Blood. 106: 2022-2022. DOI: 10.1182/Blood.V106.11.2022.2022  0.308
2005 Kline J, Pollyea D, Artz A, Stock W, Rich E, Godley L, Zimmerman T, van Besien K. Ganciclovir and high-dose valacyclovir reduce cytomegalovirus reactivation in patients receiving allogeneic stem cell transplantation with Campath-1H–based conditioning regimens Biology of Blood and Marrow Transplantation. 11: 94. DOI: 10.1016/J.Bbmt.2004.12.277  0.307
2004 van Besien KW, Artz A, Smith S, Rich E, Godley L, Jones D, Cerro PD, Switzer D, Casey B, Odenike O, Thirman M, Daugherty C, Zimmerman TM, Larson R, Stock W. Fludarabine Melphalan and Alemtuzumab (Campath) Conditioning for Pts with High Risk Myeloid Malignancies. High Cure Rate for Pts with Low Leukemia Burden. Blood. 104: 2321-2321. DOI: 10.1182/Blood.V104.11.2321.2321  0.307
2004 Ozer O, Anastasi J, Vardiman JW, Godley LA. Identical Novel C-Kit Transcripts in Two Patients with Mast Cell Leukemia. Blood. 104: 2001-2001. DOI: 10.1182/Blood.V104.11.2001.2001  0.412
2004 Pollyea DA, Artz AS, Stock W, Smith SM, Daugherty C, Godley L, Zimmerman T, Odenike OM, Thirman M, Rich E, Larson R, Van Besien K. Clinical Predictors of Transplant Related Mortality after Reduced Intensity Allogeneic Stem Cell Transplantation (RIST). Blood. 104: 1145-1145. DOI: 10.1182/Blood.V104.11.1145.1145  0.307
2002 Qian Z, Fernald AA, Godley LA, Larson RA, Le Beau MM. Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia. Proceedings of the National Academy of Sciences of the United States of America. 99: 14925-30. PMID 12417757 DOI: 10.1073/Pnas.222491799  0.402
2001 Lai F, Godley LA, Joslin J, Fernald AA, Liu J, Espinosa R, Zhao N, Pamintuan L, Till BG, Larson RA, Qian Z, Le Beau MM. Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q). Genomics. 71: 235-45. PMID 11161817 DOI: 10.1006/Geno.2000.6414  0.325
2000 Lai F, Godley LA, Fernald AA, Orelli BJ, Pamintuan L, Zhao N, Le Beau MM. cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins. Genomics. 70: 123-30. PMID 11087669 DOI: 10.1006/Geno.2000.6345  0.33
2000 Lai F, Orelli BJ, Till BG, Godley LA, Fernald AA, Pamintuan L, Le Beau MM. Molecular characterization of KLHL3, a human homologue of the Drosophila kelch gene. Genomics. 66: 65-75. PMID 10843806 DOI: 10.1006/Geno.2000.6181  0.329
1999 Godley LA, Lai F, Liu J, Zhao N, Le Beau MM. TTID: A novel gene at 5q31 encoding a protein with titin-like features. Genomics. 60: 226-33. PMID 10486214 DOI: 10.1006/Geno.1999.5912  0.342
1996 Godley LA, Kopp JB, Eckhaus M, Paglino JJ, Owens J, Varmus HE. Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys. Genes & Development. 10: 836-50. PMID 8846920 DOI: 10.1101/Gad.10.7.836  0.321
1996 Broccoli D, Godley LA, Donehower LA, Varmus HE, de Lange T. Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation. Molecular and Cellular Biology. 16: 3765-72. PMID 8668193 DOI: 10.1128/Mcb.16.7.3765  0.302
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