Kam Yeung - Publications

Affiliations: 
College of Medicine The University of Toledo 
Area:
Molecular Biology

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Argueta CE, Figy C, Bouali S, Guo A, Yeung KC, Fenteany G. RKIP localizes to the nucleus through a bipartite nuclear localization signal and interaction with importin α to regulate mitotic progression. The Journal of Biological Chemistry. 103023. PMID 36805338 DOI: 10.1016/j.jbc.2023.103023  0.343
2023 Figy C, Guo A, Fernando VR, Furuta S, Al-Mulla F, Yeung KC. Changes in Expression of Tumor Suppressor Gene RKIP Impact How Cancers Interact with Their Complex Environment. Cancers. 15. PMID 36765912 DOI: 10.3390/cancers15030958  0.327
2022 Bach VN, Ding J, Yeung M, Conrad T, Odeh HN, Cubberly P, Figy C, Ding HF, Trumbly R, Yeung KC. A Negative Regulatory Role for RKIP in Breast Cancer Immune Response. Cancers. 14. PMID 35892864 DOI: 10.3390/cancers14153605  0.38
2021 Kalpana G, Figy C, Feng J, Tipton C, De Castro JN, Bach VN, Borile C, LaSalla A, Odeh HN, Yeung M, Garcia-Mata R, Yeung KC. The RhoA dependent anti-metastatic function of RKIP in breast cancer. Scientific Reports. 11: 17455. PMID 34465801 DOI: 10.1038/s41598-021-96709-6  0.483
2019 Kalpana G, Figy C, Yeung M, Yeung KC. Reduced RhoA expression enhances breast cancer metastasis with a concomitant increase in CCR5 and CXCR4 chemokines signaling. Scientific Reports. 9: 16351. PMID 31705019 DOI: 10.1038/s41598-019-52746-w  0.326
2019 Ren G, Zheng X, Bommarito M, Metzger S, Walia Y, Letson J, Schroering A, Kalinoski A, Weaver D, Figy C, Yeung K, Furuta S. Reduced Basal Nitric Oxide Production Induces Precancerous Mammary Lesions via ERBB2 and TGFβ. Scientific Reports. 9: 6688. PMID 31040372 DOI: 10.1038/S41598-019-43239-X  0.355
2015 Datar I, Qiu X, Ma HZ, Yeung M, Aras S, de la Serna I, Al-Mulla F, Thiery JP, Trumbly R, Fan X, Cui H, Yeung KC. RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration. Oncotarget. PMID 26375811 DOI: 10.18632/Oncotarget.5176  0.387
2015 Datar I, Feng J, Qiu X, Lewandowski J, Yeung M, Ren G, Aras S, Al-Mulla F, Cui H, Trumbly R, Arudra SK, De Las Casas LE, de la Serna I, Bitar MS, Yeung KC. RKIP Inhibits Local Breast Cancer Invasion by Antagonizing the Transcriptional Activation of MMP13. Plos One. 10: e0134494. PMID 26308852 DOI: 10.1371/Journal.Pone.0134494  0.366
2015 Escara-Wilke J, Keller JM, Ignatoski KM, Dai J, Shelley G, Mizokami A, Zhang J, Yeung ML, Yeung KC, Keller ET. Raf kinase inhibitor protein (RKIP) deficiency decreases latency of tumorigenesis and increases metastasis in a murine genetic model of prostate cancer. The Prostate. 75: 292-302. PMID 25327941 DOI: 10.1002/Pros.22915  0.428
2014 Datar I, Tegegne H, Qin K, Al-Mulla F, Bitar MS, Trumbly RJ, Yeung KC. Genetic and epigenetic control of RKIP transcription. Critical Reviews in Oncogenesis. 19: 417-30. PMID 25597352 DOI: 10.1615/Critrevoncog.2014012025  0.408
2014 Yousuf S, Duan M, Moen EL, Cross-Knorr S, Brilliant K, Bonavida B, LaValle T, Yeung KC, Al-Mulla F, Chin E, Chatterjee D. Raf kinase inhibitor protein (RKIP) blocks signal transducer and activator of transcription 3 (STAT3) activation in breast and prostate cancer. Plos One. 9: e92478. PMID 24658061 DOI: 10.1371/Journal.Pone.0092478  0.51
2014 Lee J, Lee J, Farquhar KS, Yun J, Frankenberger CA, Bevilacqua E, Yeung K, Kim EJ, Balázsi G, Rosner MR. Network of mutually repressive metastasis regulators can promote cell heterogeneity and metastatic transitions. Proceedings of the National Academy of Sciences of the United States of America. 111: E364-73. PMID 24395801 DOI: 10.1073/Pnas.1304840111  0.53
2014 Datar IJ, Feng J, Ren G, Li Z, Qiu X, Al-Mulla F, Bitar MS, Yeung M, Yeung K. Abstract 124: Effect of RKIP on MMP expression and regulation of breast cancer metastasis Cancer Research. 74: 124-124. DOI: 10.1158/1538-7445.Am2014-124  0.463
2013 Al-Mulla F, Bitar MS, Thiery JP, Zea TT, Chatterjee D, Bennett L, Park S, Edwards J, Yeung KC. Clinical implications for loss or diminution of expression of Raf-1 kinase inhibitory protein and its phosphorylated form in ductal breast cancer. American Journal of Cancer Research. 3: 446-64. PMID 24224123  0.361
2013 Marathe HG, Mehta G, Zhang X, Datar I, Mehrotra A, Yeung KC, de la Serna IL. SWI/SNF Enzymes Promote SOX10- Mediated Activation of Myelin Gene Expression Plos One. 8. PMID 23874858 DOI: 10.1371/journal.pone.0069037  0.31
2013 Lee J, Yun J, Yeung K, Bevilacqua E, Balázsi G, Rosner MR. Abstract A39: BACH1 and RKIP participate in a bistable network that affects progression to metastasis in breast Cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-A39  0.487
2012 Zhang H, Wu J, Keller JM, Yeung K, Keller ET, Fu Z. Transcriptional regulation of RKIP expression by androgen in prostate cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 30: 1340-50. PMID 23095933 DOI: 10.1159/000343323  0.497
2012 Escara-Wilke J, Yeung K, Keller ET. Raf kinase inhibitor protein (RKIP) in cancer. Cancer Metastasis Reviews. 31: 615-20. PMID 22684368 DOI: 10.1007/S10555-012-9365-9  0.569
2012 Ren G, Feng J, Datar I, Yeung AH, Saladi SV, Feng Y, de la Serna I, Yeung KC. A Micro-RNA Connection in BRaf(V600E)-Mediated Premature Senescence of Human Melanocytes. International Journal of Cell Biology. 2012: 913242. PMID 22611400 DOI: 10.1155/2012/913242  0.35
2012 Ren G, Baritaki S, Marathe H, Feng J, Park S, Beach S, Bazeley PS, Beshir AB, Fenteany G, Mehra R, Daignault S, Al-Mulla F, Keller E, Bonavida B, de la Serna I, ... Yeung KC, et al. Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer. Cancer Research. 72: 3091-104. PMID 22505648 DOI: 10.1158/0008-5472.Can-11-3546  0.751
2012 Al-Mulla F, Bitar MS, Feng J, Park S, Yeung KC. A new model for raf kinase inhibitory protein induced chemotherapeutic resistance. Plos One. 7: e29532. PMID 22279539 DOI: 10.1371/journal.pone.0029532  0.43
2011 Baritaki S, Yeung K, Huerta-Yepez S, Bonavida B. Abstract 2162: Inhibition of the metastasis suppressor RKIP by EZH2 and YY1 Cellular and Molecular Biology. 71: 2162-2162. DOI: 10.1158/1538-7445.Am2011-2162  0.346
2010 Beshir AB, Ren G, Magpusao AN, Barone LM, Yeung KC, Fenteany G. Raf kinase inhibitor protein suppresses nuclear factor-κB-dependent cancer cell invasion through negative regulation of matrix metalloproteinase expression. Cancer Letters. 299: 137-49. PMID 20855151 DOI: 10.1016/J.Canlet.2010.08.012  0.391
2010 Tang H, Park S, Sun SC, Trumbly R, Ren G, Tsung E, Yeung KC. RKIP inhibits NF-kappaB in cancer cells by regulating upstream signaling components of the IkappaB kinase complex. Febs Letters. 584: 662-8. PMID 20043910 DOI: 10.1016/J.Febslet.2009.12.051  0.772
2010 Huerta-Yepez S, Suhendan E, Rivera-Pazos CM, Antonio-Andres G, Vega MI, Baay-Guzman G, Malaponte G, Baritaki S, Yeung K, Grimm E, Bonavida B. Abstract 3374: BRAF and NRAS mutations in melanoma regulate the phosphorylation and inactivation of RKIP, the metastasis suppressor and immune surveillance cancer gene product Cancer Research. 70: 3374-3374. DOI: 10.1158/1538-7445.Am10-3374  0.511
2010 Baritaki S, Huerta-Yepez S, Yeung K, Neonakis I, Bonavida B. Abstract 2290: A novel function in metastasis for YY1 overexpression in the initiation of the EMT phenotype Cancer Research. 70: 2290-2290. DOI: 10.1158/1538-7445.Am10-2290  0.585
2010 Baritaki S, Huerta-Yepez S, Sahakyan A, Jazirehi AR, Yeung K, Bonavida B. Abstract 1466: The NO donor DETANONOate inhibits the EMT phenotype in human metastatic prostate carcinoma cell lines: pivotal roles of inhibition of NF-κB and Snail activities and induction of RKIP Cancer Research. 70: 1466-1466. DOI: 10.1158/1538-7445.Am10-1466  0.494
2009 Baritaki S, Yeung K, Palladino M, Berenson J, Bonavida B. Pivotal roles of snail inhibition and RKIP induction by the proteasome inhibitor NPI-0052 in tumor cell chemoimmunosensitization. Cancer Research. 69: 8376-85. PMID 19843864 DOI: 10.1158/0008-5472.Can-09-1069  0.497
2009 Baritaki S, Chapman A, Yeung K, Spandidos DA, Palladino M, Bonavida B. Inhibition of epithelial to mesenchymal transition in metastatic prostate cancer cells by the novel proteasome inhibitor, NPI-0052: pivotal roles of Snail repression and RKIP induction. Oncogene. 28: 3573-85. PMID 19633685 DOI: 10.1038/Onc.2009.214  0.537
2009 Baritaki S, Yeung K, Wu K, Chen H, Berenson JR, Palladino MA, Bonavida B. Inhibition of the RKIP and PTEN-Transcription Repressor Snail in B-NHL by the Proteasome Inhibitor NPI-0052: Roles of RKIP and PTEN Induction in the Reversal of Resistance to TRAIL Apoptosis. Blood. 114: 3938-3938. DOI: 10.1182/Blood.V114.22.3938.3938  0.492
2008 Woods Ignatoski KM, Grewal NK, Markwart SM, Vellaichamy A, Chinnaiyan AM, Yeung K, Ray ME, Keller ET. Loss of Raf kinase inhibitory protein induces radioresistance in prostate cancer. International Journal of Radiation Oncology, Biology, Physics. 72: 153-60. PMID 18722266 DOI: 10.1016/J.Ijrobp.2008.04.072  0.499
2008 Bonavida B, Baritaki S, Huerta-Yepez S, Vega MI, Chatterjee D, Yeung K. Novel therapeutic applications of nitric oxide donors in cancer: roles in chemo- and immunosensitization to apoptosis and inhibition of metastases. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 19: 152-7. PMID 18477483 DOI: 10.1016/J.Niox.2008.04.018  0.463
2008 Rath O, Park S, Tang HH, Banfield MJ, Brady RL, Lee YC, Dignam JD, Sedivy JM, Kolch W, Yeung KC. The RKIP (Raf-1 Kinase Inhibitor Protein) conserved pocket binds to the phosphorylated N-region of Raf-1 and inhibits the Raf-1-mediated activated phosphorylation of MEK. Cellular Signalling. 20: 935-41. PMID 18294816 DOI: 10.1016/J.Cellsig.2008.01.012  0.763
2008 Beach S, Tang H, Park S, Dhillon AS, Keller ET, Kolch W, Yeung KC. Snail is a repressor of RKIP transcription in metastatic prostate cancer cells. Oncogene. 27: 2243-8. PMID 17952120 DOI: 10.1038/Sj.Onc.1210860  0.688
2008 Mc Henry KT, Montesano R, Zhu S, Beshir AB, Tang HH, Yeung KC, Fenteany G. Raf kinase inhibitor protein positively regulates cell-substratum adhesion while negatively regulating cell-cell adhesion. Journal of Cellular Biochemistry. 103: 972-85. PMID 17668446 DOI: 10.1002/Jcb.21470  0.751
2008 Vega MI, Paniagua MM, Huerta-Yepez S, Suzuki E, Umezawa K, Yeung K, Libra M, Baritaki S, Palladino MA, Bonavida B. Synergy in Apoptosis Is Achieved in B-NHL by the Combination of Rituximab and the Novel Proteasome Inhibitor NPI-0052: Pivotal Role of Induction of the Immune Surveillance Cancer Gene Product RKIP Blood. 112: 4973-4973. DOI: 10.1182/Blood.V112.11.4973.4973  0.435
2008 Baritaki S, Huerta-Yepez S, de Lourdes Cabera-Muñoz M, Rivera-Pazos C, Yeung K, Penichet ML, Chen H, Berenson JR, Bonavida B. Unique Pattern of Raf-1 Kinase Inhibitory Protein (RKIP) Expression in Multiple Myeloma (MM): RKIP Overexpression and RKIP Phosphorylation Is Common in MM Tumor Cells Blood. 112: 2729-2729. DOI: 10.1182/Blood.V112.11.2729.2729  0.525
2008 Baritaki S, Chapman A, Wu K, Yeung K, Spandidos D, Berenson JR, Palladino MA, Bonavida B. The Novel Proteasome Inhibitor NPI-0052 Induces the Expression of Raf-1 Kinase Inhibitor Protein RKIP) in B-NHL via Inhibition of the Transcription Repressor Snail: Roles of Snail and RKIP in Sensitization to TRAIL Apoptosis Blood. 112: 2611-2611. DOI: 10.1182/Blood.V112.11.2611.2611  0.481
2007 Baritaki S, Katsman A, Chatterjee D, Yeung KC, Spandidos DA, Bonavida B. Regulation of tumor cell sensitivity to TRAIL-induced apoptosis by the metastatic suppressor Raf kinase inhibitor protein via Yin Yang 1 inhibition and death receptor 5 up-regulation. Journal of Immunology (Baltimore, Md. : 1950). 179: 5441-53. PMID 17911631 DOI: 10.4049/Jimmunol.179.8.5441  0.398
2007 Theroux S, Pereira M, Casten KS, Burwell RD, Yeung KC, Sedivy JM, Klysik J. Raf kinase inhibitory protein knockout mice: expression in the brain and olfaction deficit. Brain Research Bulletin. 71: 559-67. PMID 17292798 DOI: 10.1016/J.Brainresbull.2006.11.010  0.309
2007 Baritaki S, Yeung K, Chatterjee D, Palladino M, Bonavida B. Induction of Raf-1 Kinase Inhibitory Protein (RKIP) by the Proteasome Inhibitor NPI-0052 and Reversal of B-NHL Resistance to Apoptosis. Blood. 110: 809-809. DOI: 10.1182/Blood.V110.11.809.809  0.483
2007 Baritaki S, Huerta-Yepez S, Yeung K, Penichet M, Chen H, Shalitin D, Berenson J, Bonavida B. Unique Pattern of Raf-1 Kinase Inhibitory Protein (RKIP) Expression in Multiple Myeloma (MM) Compared to Other Tumor Types: Overexpression of RKIP and a Phosphorylated RKIP Is Common in MM Tumor Cells. Blood. 110: 4852-4852. DOI: 10.1182/Blood.V110.11.4852.4852  0.518
2007 Huerta-Yepez S, Balis V, Hernandez-Cueto A, Huerta S, Munõz-Hernandez O, Vega M, Yeung K, Waterman B, Baritaki S, Spandidos D, Bonavida B. C15. Therapeutic preclinical application of NO donor (e.g. DETANONOate) and CDDP in prostate tumor xenograft regression: molecular mechanism of synergy achieved in apoptosis Nitric Oxide. 17: 23. DOI: 10.1016/J.Niox.2007.09.060  0.315
2006 Park S, Rath O, Beach S, Xiang X, Kelly SM, Luo Z, Kolch W, Yeung KC. Regulation of RKIP binding to the N-region of the Raf-1 kinase. Febs Letters. 580: 6405-12. PMID 17097642 DOI: 10.1016/J.Febslet.2006.10.054  0.711
2005 Park S, Yeung ML, Beach S, Shields JM, Yeung KC. RKIP downregulates B-Raf kinase activity in melanoma cancer cells. Oncogene. 24: 3535-40. PMID 15782137 DOI: 10.1038/sj.onc.1208435  0.75
2004 Odabaei G, Chatterjee D, Jazirehi AR, Goodglick L, Yeung K, Bonavida B. Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis. Advances in Cancer Research. 91: 169-200. PMID 15327891 DOI: 10.1016/S0065-230X(04)91005-6  0.526
2004 Keller ET, Fu Z, Yeung K, Brennan M. Raf kinase inhibitor protein: a prostate cancer metastasis suppressor gene. Cancer Letters. 207: 131-7. PMID 15151133 DOI: 10.1016/J.Canlet.2004.02.006  0.568
2004 Chatterjee D, Bai Y, Wang Z, Beach S, Mott S, Roy R, Braastad C, Sun Y, Mukhopadhyay A, Aggarwal BB, Darnowski J, Pantazis P, Wyche J, Fu Z, Kitagwa Y, ... ... Yeung KC, et al. RKIP sensitizes prostate and breast cancer cells to drug-induced apoptosis. The Journal of Biological Chemistry. 279: 17515-23. PMID 14766752 DOI: 10.1074/Jbc.M313816200  0.742
2000 Yeung K, Janosch P, McFerran B, Rose DW, Mischak H, Sedivy JM, Kolch W. Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein. Molecular and Cellular Biology. 20: 3079-85. PMID 10757792 DOI: 10.1128/Mcb.20.9.3079-3085.2000  0.478
1999 Yeung K, Seitz T, Li S, Janosch P, McFerran B, Kaiser C, Fee F, Katsanakis KD, Rose DW, Mischak H, Sedivy JM, Kolch W. Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP. Nature. 401: 173-7. PMID 10490027 DOI: 10.1038/43686  0.468
1994 Kraus VB, Inostroza JA, Yeung K, Reinberg D, Nevins JR. Interaction of the Dr1 inhibitory factor with the TATA binding protein is disrupted by adenovirus E1A Proceedings of the National Academy of Sciences of the United States of America. 91: 6279-6282. PMID 8022773 DOI: 10.1073/Pnas.91.14.6279  0.396
Show low-probability matches.