Arthur I. Cederbaum - Publications

Affiliations: 
Genetics and Genomic Sciences Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Genetics, Molecular Biology

324 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chen X, Acquaah-Mensah GK, Denning KL, Peterson JM, Wang K, Denvir J, Hong F, Cederbaum AI, Lu Y. High fat diet induces fibrosis in mice lacking CYP2A5 and PPARα: A new model for steatohepatitis-associated fibrosis. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 32877213 DOI: 10.1152/Ajpgi.00213.2020  0.301
2019 Chen X, Wang K, Cederbaum AI, Lu Y. Suppressed hepatocyte proliferation via a ROS-HNE-P21 pathway is associated with nicotine- and cotinine-enhanced alcoholic fatty liver in mice. Biochemical and Biophysical Research Communications. PMID 30876690 DOI: 10.1016/J.Bbrc.2019.03.021  0.384
2018 Chen X, Owoseni E, Salamat J, Cederbaum AI, Lu Y. Nicotine enhances alcoholic fatty liver in mice: Role of CYP2A5. Archives of Biochemistry and Biophysics. PMID 30222954 DOI: 10.1016/J.Abb.2018.09.012  0.35
2018 Lu Y, Cederbaum AI. Cytochrome P450s and Alcoholic Liver Disease. Current Pharmaceutical Design. 24: 1502-1517. PMID 29637855 DOI: 10.2174/1381612824666180410091511  0.408
2018 Wang K, Chen X, Ward SC, Liu Y, Ouedraogo Y, Xu C, Cederbaum AI, Lu Y. CYP2A6 is associated with obesity: studies in human samples and a high fat diet mouse model. International Journal of Obesity (2005). PMID 29568101 DOI: 10.1038/S41366-018-0037-X  0.3
2017 Hicks DF, Goossens N, Blas-García A, Tsuchida T, Wooden B, Wallace MC, Nieto N, Lade A, Redhead B, Cederbaum AI, Dudley JT, Fuchs BC, Lee YA, Hoshida Y, Friedman SL. Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells. Scientific Reports. 7: 42563. PMID 28256512 DOI: 10.1038/Srep42563  0.348
2017 Chen X, Ward SC, Cederbaum AI, Xiong H, Lu Y. Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis. Toxicology. PMID 28131861 DOI: 10.1016/J.Tox.2017.01.016  0.381
2017 Cederbaum A. Editorial: New Insights into Mechanisms of Alcohol-Induced Fatty Liver. Current Molecular Pharmacology. 10: 162-164. PMID 26278394 DOI: 10.2174/1874467208999150817110848  0.342
2015 Mahli A, Thasler WE, Patsenker E, Müller S, Stickel F, Müller M, Seitz HK, Cederbaum AI, Hellerbrand C. Identification of cytochrome CYP2E1 as critical mediator of synergistic effects of alcohol and cellular lipid accumulation in hepatocytes in vitro. Oncotarget. PMID 26497211 DOI: 10.18632/Oncotarget.6203  0.379
2015 Hong F, Si C, Gao P, Cederbaum AI, Xiong H, Lu Y. The role of CYP2A5 in liver injury and fibrosis: chemical-specific difference. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 26363552 DOI: 10.1007/S00210-015-1172-8  0.32
2015 Hong F, Liu X, Ward SS, Xiong H, Cederbaum AI, Lu Y. Absence of cytochrome P450 2A5 enhances alcohol-induced liver injury in mice. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 47: 470-7. PMID 25804444 DOI: 10.1016/J.Dld.2015.02.012  0.434
2015 Cederbaum AI. Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implications. Redox Biology. 4: 60-73. PMID 25498968 DOI: 10.1016/J.Redox.2014.11.008  0.332
2015 Cederbaum AI, Lu Y, Wang X, Wu D. Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury. Advances in Experimental Medicine and Biology. 815: 145-72. PMID 25427906 DOI: 10.1007/978-3-319-09614-8_9  0.435
2015 Mahli A, Thasler W, Müller M, Seitz H, Cederbaum A, Hellerbrand C. Identification of cytochrome CYP2E1 as critical mediator of alcohol effects on steatotic hepatocytes Zeitschrift Fur Gastroenterologie. 53. DOI: 10.1055/S-0034-1397138  0.328
2015 Cederbaum AI. CYP2E1- and TNFalpha/LPS-Induced Oxidative Stress and MAPK Signaling Pathways in Alcoholic Liver Disease Current Pathobiology Reports. 3: 263-272. DOI: 10.1007/S40139-015-0092-0  0.484
2014 Cederbaum AI. Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction. Redox Biology. 2: 1048-54. PMID 25454746 DOI: 10.1016/J.Redox.2014.09.007  0.481
2014 Liu H, Lou G, Li C, Wang X, Cederbaum AI, Gan L, Xie B. HBx inhibits CYP2E1 gene expression via downregulating HNF4α in human hepatoma cells. Plos One. 9: e107913. PMID 25238230 DOI: 10.1371/Journal.Pone.0107913  0.337
2014 Wang Y, Kou Y, Wang X, Cederbaum A, Wang R. Multifactorial comparative proteomic study of cytochrome P450 2E1 function in chronic alcohol administration. Plos One. 9: e92504. PMID 24658151 DOI: 10.1371/Journal.Pone.0092504  0.47
2014 Yang L, Rozenfeld R, Wu D, Devi LA, Zhang Z, Cederbaum A. Cannabidiol protects liver from binge alcohol-induced steatosis by mechanisms including inhibition of oxidative stress and increase in autophagy. Free Radical Biology & Medicine. 68: 260-7. PMID 24398069 DOI: 10.1016/J.Freeradbiomed.2013.12.026  0.437
2014 Cederbaum AI. Nrf2 and antioxidant defense against CYP2E1 toxicity. Sub-Cellular Biochemistry. 67: 105-30. PMID 23400918 DOI: 10.1007/978-94-007-5881-0_2  0.43
2013 Wu D, Cederbaum AI. Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK. Redox Biology. 1: 552-65. PMID 24273738 DOI: 10.1016/J.Redox.2013.10.008  0.522
2013 Wang X, Wu D, Yang L, Gan L, Cederbaum AI. Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo. Free Radical Biology & Medicine. 63: 175-86. PMID 23669278 DOI: 10.1016/J.Freeradbiomed.2013.05.009  0.433
2013 Forsyth CB, Voigt RM, Shaikh M, Tang Y, Cederbaum AI, Turek FW, Keshavarzian A. Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G185-95. PMID 23660503 DOI: 10.1152/Ajpgi.00354.2012  0.356
2012 Cederbaum AI. CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment. Drug Metabolism and Drug Interactions. 27: 125-44. PMID 23104821 DOI: 10.1515/Dmdi-2012-0014  0.428
2012 Wu D, Wang X, Zhou R, Yang L, Cederbaum AI. Alcohol steatosis and cytotoxicity: the role of cytochrome P4502E1 and autophagy. Free Radical Biology & Medicine. 53: 1346-57. PMID 22819980 DOI: 10.1016/J.Freeradbiomed.2012.07.005  0.498
2012 Yang L, Wu D, Wang X, Cederbaum AI. Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver. Free Radical Biology & Medicine. 53: 1170-80. PMID 22749809 DOI: 10.1016/J.Freeradbiomed.2012.06.029  0.422
2012 Lu Y, Zhang XH, Cederbaum AI. Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway. Toxicological Sciences : An Official Journal of the Society of Toxicology. 128: 427-38. PMID 22552773 DOI: 10.1093/Toxsci/Kfs164  0.407
2012 An L, Wang X, Cederbaum AI. Cytokines in alcoholic liver disease. Archives of Toxicology. 86: 1337-48. PMID 22367091 DOI: 10.1007/S00204-012-0814-6  0.384
2012 Cederbaum AI, Yang L, Wang X, Wu D. CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases. International Journal of Hepatology. 2012: 582790. PMID 22028977 DOI: 10.1155/2012/582790  0.475
2011 Andreo U, Elkind J, Blachford C, Cederbaum AI, Fisher EA. Role of superoxide radical anion in the mechanism of apoB100 degradation induced by DHA in hepatic cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3554-60. PMID 21757500 DOI: 10.1096/Fj.11-182725  0.41
2011 Wang X, Wu D, Yang L, Cederbaum AI. Hepatotoxicity mediated by pyrazole (cytochrome P450 2E1) plus tumor necrosis factor alpha treatment occurs in c-Jun N-terminal kinase 2-/- but not in c-Jun N-terminal kinase 1-/- mice. Hepatology (Baltimore, Md.). 54: 1753-66. PMID 21748763 DOI: 10.1002/Hep.24540  0.366
2011 Yang L, Wu D, Wang X, Cederbaum AI. Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells. Free Radical Biology & Medicine. 51: 185-96. PMID 21557999 DOI: 10.1016/J.Freeradbiomed.2011.04.030  0.43
2011 Lu Y, Zhuge J, Wu D, Cederbaum AI. Ethanol induction of CYP2A5: permissive role for CYP2E1. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 330-6. PMID 21051534 DOI: 10.1124/Dmd.110.035691  0.399
2010 Cederbaum AI. Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity. Digestive Diseases (Basel, Switzerland). 28: 802-11. PMID 21525766 DOI: 10.1159/000324289  0.477
2010 Wu D, Wang X, Zhou R, Cederbaum A. CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophaghy in HepG2 E47 cells Biochemical and Biophysical Research Communications. 402: 116-122. PMID 20932821 DOI: 10.1016/J.Bbrc.2010.09.127  0.453
2010 Lu Y, Wu D, Wang X, Ward SC, Cederbaum AI. Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice. Free Radical Biology & Medicine. 49: 1406-16. PMID 20692331 DOI: 10.1016/J.Freeradbiomed.2010.07.026  0.459
2010 Wu D, Cederbaum A. Activation of ASK-1 and downstream MAP kinases in cytochrome P4502E1 potentiated tumor necrosis factor α liver injury Free Radical Biology and Medicine. 49: 348-360. PMID 20438834 DOI: 10.1016/J.Freeradbiomed.2010.04.021  0.458
2010 Cederbaum AI. Hepatoprotective effects of S-adenosyl-L-methionine against alcohol- and cytochrome P450 2E1-induced liver injury. World Journal of Gastroenterology. 16: 1366-76. PMID 20238404 DOI: 10.3748/Wjg.V16.I11.1366  0.38
2010 Lu Y, Cederbaum AI. CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction. Genes & Nutrition. 5: 149-67. PMID 19798529 DOI: 10.1007/S12263-009-0150-5  0.44
2010 Yang L, Cederbaum A. Thioredoxin is Critical in Protecting HepG2 Cells from CYP2E1induced Oxidative Stress Free Radical Biology and Medicine. 49: S105. DOI: 10.1016/J.Freeradbiomed.2010.10.277  0.38
2009 Cederbaum A. Nrf2 and antioxidant defense against CYP2E1 toxicity. Expert Opinion On Drug Metabolism & Toxicology. 5: 1223-44. PMID 19671018 DOI: 10.1517/17425250903143769  0.426
2009 Cederbaum A. Nrf2 and antioxidant defense against CYP2E1 toxicity. Expert Opinion On Drug Metabolism & Toxicology. 5: 1223-44. PMID 19671018 DOI: 10.1517/17425250903143769  0.426
2009 Wang X, Lu Y, Xie B, Cederbaum AI. Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: role of CYP2E1 and TNF-alpha and activation of JNK and P38 MAP kinase. Free Radical Biology & Medicine. 47: 518-28. PMID 19477265 DOI: 10.1016/J.Freeradbiomed.2009.05.021  0.436
2009 Cederbaum AI, Lu Y, Wu D. Role of oxidative stress in alcohol-induced liver injury. Archives of Toxicology. 83: 519-48. PMID 19448996 DOI: 10.1007/S00204-009-0432-0  0.521
2009 Wu D, Cederbaum AI. Oxidative stress and alcoholic liver disease. Seminars in Liver Disease. 29: 141-54. PMID 19387914 DOI: 10.1055/S-0029-1214370  0.522
2009 Wu D, Xu C, Cederbaum A. Role of nitric oxide and nuclear factor-κB in the CYP2E1 potentiation of tumor necrosis factor α hepatotoxicity in mice Free Radical Biology and Medicine. 46: 480-491. PMID 19063961 DOI: 10.1016/J.Freeradbiomed.2008.11.001  0.441
2009 Caro AA, Evans KL, Cederbaum AI. CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells. Toxicology. 255: 171-6. PMID 19028543 DOI: 10.1016/J.Tox.2008.10.020  0.37
2009 Zhuge J, Cederbaum AI. Inhibition of the mitochondrial permeability transition by cyclosporin A prevents pyrazole plus lipopolysaccharide-induced liver injury in mice. Free Radical Biology & Medicine. 46: 406-13. PMID 19026739 DOI: 10.1016/J.Freeradbiomed.2008.10.037  0.395
2008 Lu Y, Gong P, Cederbaum AI. Pyrazole induced oxidative liver injury independent of CYP2E1/2A5 induction due to Nrf2 deficiency. Toxicology. 252: 9-16. PMID 18721845 DOI: 10.1016/J.Tox.2008.07.058  0.425
2008 Wang X, Cederbaum AI. S-adenosyl-L-methionine decreases the elevated hepatotoxicity induced by Fas agonistic antibody plus acute ethanol pretreatment in mice. Archives of Biochemistry and Biophysics. 477: 1-11. PMID 18482574 DOI: 10.1016/J.Abb.2008.04.033  0.445
2008 Lu Y, Zhuge J, Wang X, Bai J, Cederbaum AI. Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice. Hepatology (Baltimore, Md.). 47: 1483-94. PMID 18393316 DOI: 10.1002/Hep.22222  0.447
2008 Wu D, Cederbaum AI. Development and properties of HepG2 cells that constitutively express CYP2E1. Methods in Molecular Biology (Clifton, N.J.). 447: 137-50. PMID 18369917 DOI: 10.1007/978-1-59745-242-7_11  0.495
2008 Wu D, Cederbaum A. Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha-induced liver injury through activation of mitogen-activated protein kinases in mice. Hepatology. 47: 1005-1017. PMID 18095305 DOI: 10.1002/Hep.22087  0.377
2008 Lu Y, Cederbaum AI. CYP2E1 and oxidative liver injury by alcohol. Free Radical Biology & Medicine. 44: 723-38. PMID 18078827 DOI: 10.1016/J.Freeradbiomed.2007.11.004  0.534
2008 Jimenez-Lopez JM, Wu D, Cederbaum AI. Synergistic toxicity induced by prolonged glutathione depletion and inhibition of nuclear factor-kappaB signaling in liver cells. Toxicology in Vitro : An International Journal Published in Association With Bibra. 22: 106-15. PMID 17920235 DOI: 10.1016/J.Tiv.2007.08.012  0.391
2008 Cederbaum AI. The effect of cyanamide on acetaldehyde oxidation by isolated rat liver mitochondria and on the inhibition of pyruvate oxidation by acetaldehyde. Alcoholism: Clinical and Experimental Research. 5: 38-44. PMID 7013545 DOI: 10.1111/J.1530-0277.1981.Tb04862.X  0.471
2007 Lu Y, Cederbaum A. The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin Free Radical Biology and Medicine. 43: 1061-1075. PMID 17761302 DOI: 10.1016/J.Freeradbiomed.2007.06.021  0.366
2007 Donohue TM, Cederbaum AI, French SW, Barve S, Gao B, Osna NA. Role of the proteasome in ethanol-induced liver pathology Alcoholism: Clinical and Experimental Research. 31: 1446-1459. PMID 17760783 DOI: 10.1111/J.1530-0277.2007.00454.X  0.451
2007 Zhuge J, Cederbaum AI. Depletion of S-adenosyl-l-methionine with cycloleucine potentiates cytochrome P450 2E1 toxicity in primary rat hepatocytes. Archives of Biochemistry and Biophysics. 466: 177-85. PMID 17640612 DOI: 10.1016/J.Abb.2007.06.007  0.453
2007 Dey A, Cederbaum AI. Induction of cytochrome promotes liver injury in ob/ob mice Hepatology. 45: 1355-1365. PMID 17538970 DOI: 10.1002/Hep.21603  0.398
2007 Kessova IG, Cederbaum AI. Mitochondrial alterations in livers of Sod1-/- mice fed alcohol. Free Radical Biology & Medicine. 42: 1470-80. PMID 17448893 DOI: 10.1016/J.Freeradbiomed.2007.01.044  0.451
2007 Dey A, Caro AA, Cederbaum AI. S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury. American Journal of Physiology. Gastrointestinal and Liver Physiology. 293: G91-103. PMID 17446309 DOI: 10.1152/Ajpgi.00004.2007  0.371
2007 Dey A, Cederbaum AI. Geldanamycin, an inhibitor of Hsp90 increases cytochrome P450 2E1 mediated toxicity in HepG2 cells through sustained activation of the p38MAPK pathway Archives of Biochemistry and Biophysics. 461: 275-286. PMID 17382893 DOI: 10.1016/J.Abb.2007.02.014  0.352
2007 Wang X, Cederbaum AI. Acute ethanol pretreatment increases FAS-mediated liver injury in mice: role of oxidative stress and CYP2E1-dependent and -independent pathways. Free Radical Biology & Medicine. 42: 971-84. PMID 17349925 DOI: 10.1016/J.Freeradbiomed.2006.12.023  0.49
2007 Caro AA, Cederbaum AI. Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1. Archives of Biochemistry and Biophysics. 457: 252-63. PMID 17118330 DOI: 10.1016/J.Abb.2006.10.018  0.361
2006 Bai J, Cederbaum AI. Cycloheximide protects HepG2 cells from serum withdrawal-induced apoptosis by decreasing p53 and phosphorylated p53 levels. The Journal of Pharmacology and Experimental Therapeutics. 319: 1435-43. PMID 16971506 DOI: 10.1124/Jpet.106.110007  0.335
2006 Zhuge J, Cederbaum AI. Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1. Free Radical Biology & Medicine. 41: 1100-12. PMID 16962935 DOI: 10.1016/J.Freeradbiomed.2006.06.017  0.374
2006 Cederbaum AI. Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells. Journal of Gastroenterology and Hepatology. 21: S22-5. PMID 16958665 DOI: 10.1111/J.1440-1746.2006.04595.X  0.516
2006 Wu D, Cederbaum A. Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity. Toxicology and Applied Pharmacology. 216: 282-292. PMID 16938321 DOI: 10.1016/J.Taap.2006.05.019  0.446
2006 Cederbaum AI. CYP2E1--biochemical and toxicological aspects and role in alcohol-induced liver injury. The Mount Sinai Journal of Medicine, New York. 73: 657-72. PMID 16878272 DOI: 10.1007/978-0-387-77300-1_6  0.529
2006 Lu Y, Cederbaum AI. Enhancement by pyrazole of lipopolysaccharide-induced liver injury in mice: role of cytochrome P450 2E1 and 2A5. Hepatology (Baltimore, Md.). 44: 263-74. PMID 16799984 DOI: 10.1002/Hep.21241  0.368
2006 Caro AA, Cederbaum AI. Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity. The Journal of Pharmacology and Experimental Therapeutics. 318: 360-72. PMID 16624972 DOI: 10.1124/Jpet.106.102921  0.36
2006 Gong P, Cederbaum AI. Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity. The Journal of Biological Chemistry. 281: 14573-9. PMID 16551616 DOI: 10.1074/Jbc.M600613200  0.41
2006 Bai J, Cederbaum AI. Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 91: 365-71. PMID 16549397 DOI: 10.1093/Toxsci/Kfj165  0.395
2006 Inami K, Nims RW, Srinivasan A, Citro ML, Saavedra JE, Cederbaum AI, Keefer LK. Metabolism of a liver-selective nitric oxide-releasing agent, V-PYRRO/NO, by human microsomal cytochromes P450. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 14: 309-15. PMID 16545970 DOI: 10.1016/J.Niox.2006.01.003  0.436
2006 Dey A, Cederbaum AI. Geldanamycin, an inhibitor of Hsp90, potentiates cytochrome P4502E1-mediated toxicity in HepG2 cells Journal of Pharmacology and Experimental Therapeutics. 317: 1391-1399. PMID 16513847 DOI: 10.1124/Jpet.106.101808  0.374
2006 Dey A, Kessova IG, Cederbaum AI. Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1. Archives of Biochemistry and Biophysics. 447: 155-66. PMID 16497268 DOI: 10.1016/J.Abb.2006.01.013  0.374
2006 Dey A, Cederbaum AI. Alcohol and oxidative liver injury Hepatology. 43. PMID 16447273 DOI: 10.1002/Hep.20957  0.498
2006 Caro AA, Cederbaum AI. Role of cytochrome P450 in phospholipase A2- and arachidonic acid-mediated cytotoxicity. Free Radical Biology & Medicine. 40: 364-75. PMID 16443151 DOI: 10.1016/J.Freeradbiomed.2005.10.044  0.41
2006 Bai J, Cederbaum AI. Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione. The Journal of Biological Chemistry. 281: 5128-36. PMID 16380384 DOI: 10.1074/Jbc.M510484200  0.464
2006 Gong P, Cederbaum AI. Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1. Hepatology (Baltimore, Md.). 43: 144-53. PMID 16374848 DOI: 10.1002/Hep.21004  0.498
2006 Wang X, Cederbaum AI. S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice. The Journal of Pharmacology and Experimental Therapeutics. 317: 44-52. PMID 16373529 DOI: 10.1124/Jpet.105.098004  0.437
2006 Zhuge J, Cederbaum AI. Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1. Free Radical Biology & Medicine. 40: 63-74. PMID 16337880 DOI: 10.1016/J.Freeradbiomed.2005.08.012  0.44
2006 Wu D, Cederbaum AI. Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G674-84. PMID 16306132 DOI: 10.1152/Ajpgi.00406.2005  0.431
2006 Lu Y, Cederbaum AI. Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1. Toxicological Sciences : An Official Journal of the Society of Toxicology. 89: 515-23. PMID 16251482 DOI: 10.1093/Toxsci/Kfj031  0.471
2005 Jimenez-Lopez JM, Cederbaum AI. CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury. Expert Opinion On Drug Metabolism & Toxicology. 1: 671-85. PMID 16863432 DOI: 10.1517/17425255.1.4.671  0.505
2005 Lakshman R, Cederbaum AI, Hoek JB, Konishi M, Koop D, Donohu TM. Use of CYP2E1-transfected human liver cell lines in elucidating the actions of ethanol. Alcoholism, Clinical and Experimental Research. 29: 1726-34. PMID 16205373 DOI: 10.1097/01.Alc.0000179379.03078.8F  0.43
2005 Wang X, Lu Y, Cederbaum AI. Induction of cytochrome P450 2E1 increases hepatotoxicity caused by Fas agonistic Jo2 antibody in mice. Hepatology (Baltimore, Md.). 42: 400-10. PMID 16025513 DOI: 10.1002/Hep.20792  0.412
2005 Wu D, Cederbaum AI. Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1. Toxicology and Applied Pharmacology. 207: 70-6. PMID 16019049 DOI: 10.1016/J.Taap.2005.01.057  0.544
2005 Kessova IG, Cederbaum AI. The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells. The Journal of Pharmacology and Experimental Therapeutics. 315: 304-12. PMID 16002458 DOI: 10.1124/Jpet.105.088047  0.44
2005 Nieto N, Cederbaum AI. S-adenosylmethionine blocks collagen I production by preventing transforming growth factor-beta induction of the COL1A2 promoter. The Journal of Biological Chemistry. 280: 30963-74. PMID 15983038 DOI: 10.1074/Jbc.M503569200  0.313
2005 Lu Y, Wang X, Cederbaum AI. Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole. American Journal of Physiology. Gastrointestinal and Liver Physiology. 289: G308-19. PMID 15845871 DOI: 10.1152/Ajpgi.00054.2005  0.365
2005 Caro AA, Cederbaum AI. Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine. Biochemical Pharmacology. 69: 1081-93. PMID 15763544 DOI: 10.1016/J.Bcp.2005.01.007  0.424
2005 Carmiel-Haggai M, Cederbaum AI, Nieto N. A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 136-8. PMID 15522905 DOI: 10.1096/Fj.04-2291Fje  0.385
2005 Jimenez-Lopez JM, Cederbaum AI. Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells. The Journal of Pharmacology and Experimental Therapeutics. 312: 998-1006. PMID 15494549 DOI: 10.1124/Jpet.104.076737  0.456
2004 Gong P, Hu B, Cederbaum AI. Diallyl sulfide induces heme oxygenase-1 through MAPK pathway. Archives of Biochemistry and Biophysics. 432: 252-60. PMID 15542064 DOI: 10.1016/J.Abb.2004.09.024  0.407
2004 Bai J, Cederbaum AI. Adenovirus mediated overexpression of CYP2E1 increases sensitivity of HepG2 cells to acetaminophen induced cytotoxicity. Molecular and Cellular Biochemistry. 262: 165-76. PMID 15532721 DOI: 10.1023/B:Mcbi.0000038232.61760.9E  0.351
2004 Wu D, Cederbaum A. Glutathione Depletion in CYP2E1-Expressing Liver Cells Induces Toxicity Due to the Activation of p38 Mitogen-Activated Protein Kinase and Reduction of Nuclear Factor-κB DNA Binding Activity Molecular Pharmacology. 66: 749-760. PMID 15322268 DOI: 10.1124/Mol.104.002048  0.441
2004 Pan M, Cederbaum AI, Zhang YL, Ginsberg HN, Williams KJ, Fisher EA. Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production. The Journal of Clinical Investigation. 113: 1277-87. PMID 15124019 DOI: 10.1172/Jci19197  0.403
2004 Caro AA, Cederbaum AI. Antioxidant properties of S-adenosyl-L-methionine in Fe(2+)-initiated oxidations. Free Radical Biology & Medicine. 36: 1303-16. PMID 15110395 DOI: 10.1016/J.Freeradbiomed.2004.02.015  0.443
2004 Jimenez-Lopez JM, Cederbaum AI. Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity. Free Radical Biology & Medicine. 36: 359-70. PMID 15036355 DOI: 10.1016/J.Freeradbiomed.2003.11.016  0.543
2004 Gong P, Cederbaum AI, Nieto N. Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity. Free Radical Biology & Medicine. 36: 307-18. PMID 15036350 DOI: 10.1016/J.Freeradbiomed.2003.10.017  0.471
2004 Caro AA, Cederbaum AI. Oxidative stress, toxicology, and pharmacology of CYP2E1. Annual Review of Pharmacology and Toxicology. 44: 27-42. PMID 14744237 DOI: 10.1146/Annurev.Pharmtox.44.101802.121704  0.52
2004 Gong P, Cederbaum AI, Nieto N. The liver-selective nitric oxide donor O2-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) protects HepG2 cells against cytochrome P450 2E1-dependent toxicity. Molecular Pharmacology. 65: 130-8. PMID 14722244 DOI: 10.1124/Mol.65.1.130  0.465
2004 Konishi M, Kato S, Kajihara M, Cederbaum A, Ishii H. Ethanol upregulates pro-fibrogenic connective tissue growth factor (CTGF) gene expression in HepG2 cells via cytochrome P450 2E1-mediated ethanol oxidation Hepatology Research. 28: 102-108. DOI: 10.1016/J.Hepres.2003.12.003  0.486
2003 Wu D, Cederbaum AI. Alcohol, oxidative stress, and free radical damage. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 27: 277-84. PMID 15540798  0.361
2003 Carmiel-Haggai M, Cederbaum AI, Nieto N. Binge ethanol exposure increases liver injury in obese rats. Gastroenterology. 125: 1818-33. PMID 14724834 DOI: 10.1053/J.Gastro.2003.09.019  0.333
2003 Pérez MJ, Cederbaum AI. Adenovirus-mediated expression of Cu/Zn- or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity. Hepatology (Baltimore, Md.). 38: 1146-58. PMID 14578853 DOI: 10.1053/Jhep.2003.50479  0.41
2003 Kessova IG, Ho YS, Thung S, Cederbaum AI. Alcohol-induced liver injury in mice lacking Cu, Zn-superoxide dismutase. Hepatology (Baltimore, Md.). 38: 1136-45. PMID 14578852 DOI: 10.1053/Jhep.2003.50450  0.476
2003 Kessova I, Cederbaum AI. CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury. Current Molecular Medicine. 3: 509-18. PMID 14527082 DOI: 10.2174/1566524033479609  0.529
2003 Cederbaum AI. Iron and CYP2E1-dependent oxidative stress and toxicity. Alcohol (Fayetteville, N.Y.). 30: 115-20. PMID 12957295 DOI: 10.1016/S0741-8329(03)00104-6  0.454
2003 Ishii H, Adachi M, Fernández-Checa JC, Cederbaum AI, Deaciuc IV, Nanji AA. Role of apoptosis in alcoholic liver injury. Alcoholism, Clinical and Experimental Research. 27: 1207-12. PMID 12878930 DOI: 10.1111/J.1530-0277.2003.Tb02886.X  0.408
2003 Caro AA, Cederbaum AI. Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells. The Journal of Biological Chemistry. 278: 33866-77. PMID 12813050 DOI: 10.1074/Jbc.M300408200  0.349
2003 Gong P, Cederbaum AI, Nieto N. Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway. The Journal of Biological Chemistry. 278: 29693-700. PMID 12777398 DOI: 10.1074/Jbc.M304728200  0.478
2003 Pérez MJ, Cederbaum AI. Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells. Hepatology (Baltimore, Md.). 37: 1395-404. PMID 12774019 DOI: 10.1053/Jhep.2003.50228  0.555
2003 Pérez MJ, Cederbaum AI. Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity. Free Radical Biology & Medicine. 34: 443-55. PMID 12566070 DOI: 10.1016/S0891-5849(02)01302-3  0.455
2003 Nieto N, Cederbaum AI. Increased Sp1-dependent transactivation of the LAMgamma 1 promoter in hepatic stellate cells co-cultured with HepG2 cells overexpressing cytochrome P450 2E1. The Journal of Biological Chemistry. 278: 15360-72. PMID 12529372 DOI: 10.1074/Jbc.M206790200  0.385
2003 Nieto N, Marí M, Cederbaum AI. Cytochrome P450 2E1 responsiveness in the promoter of glutamate-cysteine ligase catalytic subunit. Hepatology (Baltimore, Md.). 37: 96-106. PMID 12500194 DOI: 10.1053/Jhep.2003.50003  0.405
2003 Bai J, Cederbaum AI. Catalase protects HepG2 cells from apoptosis induced by DNA-damaging agents by accelerating the degradation of p53. The Journal of Biological Chemistry. 278: 4660-7. PMID 12468545 DOI: 10.1074/Jbc.M206273200  0.381
2003 Wu D, Cederbaum AI. Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity. Journal of Biological Chemistry. 278: 1115-1124. PMID 12403788 DOI: 10.1074/Jbc.M207856200  0.461
2002 Caro AA, Cederbaum AI. Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1 Archives of Biochemistry and Biophysics. 408: 162-170. PMID 12464267 DOI: 10.1016/S0003-9861(02)00544-1  0.37
2002 Pérez MJ, Cederbaum AI. Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity. Free Radical Biology & Medicine. 33: 111-27. PMID 12086689 DOI: 10.1016/S0891-5849(02)00865-1  0.485
2002 Wu D, Cederbaum AI. Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria. Hepatology. 35: 1420-1430. PMID 12029627 DOI: 10.1053/Jhep.2002.33639  0.411
2002 Marı́ M, Bai J, Cederbaum AI. Adenovirus-Mediated Overexpression of Catalase in the Cytosolic or Mitochondrial Compartment Protects against Toxicity Caused by Glutathione Depletion in HepG2 Cells Expressing CYP2E1 Journal of Pharmacology and Experimental Therapeutics. 301: 111-118. PMID 11907164 DOI: 10.1124/Jpet.301.1.111  0.48
2002 Jaeschke H, Gores GJ, Cederbaum AI, Hinson JA, Pessayre D, Lemasters JJ. Mechanisms of hepatotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 65: 166-76. PMID 11812920 DOI: 10.1093/Toxsci/65.2.166  0.502
2002 Nieto N, Friedman SL, Cederbaum AI. Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species Hepatology. 35: 62-73. PMID 11786960 DOI: 10.1053/Jhep.2002.30362  0.427
2002 Nieto N, Friedman SL, Cederbaum AI. Cytochrome P450 2E1-derived Reactive Oxygen Species Mediate Paracrine Stimulation of Collagen I Protein Synthesis by Hepatic Stellate Cells Journal of Biological Chemistry. 277: 9853-9864. PMID 11782477 DOI: 10.1074/Jbc.M110506200  0.361
2002 Marı́ M, Bai J, Cederbaum AI. Toxicity by pyruvate in HepG2 cells depleted of glutathione: role of mitochondria. Free Radical Biology and Medicine. 32: 73-83. PMID 11755319 DOI: 10.1016/S0891-5849(01)00759-6  0.41
2002 Caro AA, Cederbaum AI. Role of calcium and calcium-activated proteases in CYP2E1-dependent toxicity in HEPG2 cells Journal of Biological Chemistry. 277: 104-113. PMID 11689564 DOI: 10.1074/Jbc.M107864200  0.346
2001 Cederbaum AI, Wu D, Mari M, Bai J. CYP2E1-dependent toxicity and oxidative stress in HepG2 cells. Free Radical Biology and Medicine. 31: 1539-1543. PMID 11744327 DOI: 10.1016/S0891-5849(01)00743-2  0.534
2001 Cederbaum AI. Introduction-serial review: alcohol, oxidative stress and cell injury. Free Radical Biology and Medicine. 31: 1524-1526. PMID 11744324 DOI: 10.1016/S0891-5849(01)00741-9  0.365
2001 Caro AA, Cederbaum AI, Stoyanovsky DA. Oxidation of the ketoxime acetoxime to nitric oxide by oxygen radical-generating systems. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 5: 413-24. PMID 11485379 DOI: 10.1006/Niox.2001.0362  0.471
2001 Chen J, Clemens DL, Cederbaum AI, Gao B. Ethanol inhibits the JAK-STAT signaling pathway in freshly isolated rat hepatocytes but not in cultured hepatocytes or HepG2 cells: evidence for a lack of involvement of ethanol metabolism. Clinical Biochemistry. 34: 203-9. PMID 11408018 DOI: 10.1016/S0009-9120(01)00216-8  0.408
2001 Bai J, Cederbaum AI. Mitochondrial catalase and oxidative injury. Neurosignals. 10: 189-199. PMID 11351128 DOI: 10.1159/000046887  0.341
2001 Pérez MJ, Cederbaum AI. Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity. Free Radical Biology and Medicine. 30: 734-746. PMID 11275473 DOI: 10.1016/S0891-5849(01)00461-0  0.459
2001 Wu D, Cederbaum AI. Sodium Salicylate Increases CYP2E1 Levels and Enhances Arachidonic Acid Toxicity in HepG2 Cells and Cultured Rat Hepatocytes Molecular Pharmacology. 59: 795-805. PMID 11259624 DOI: 10.1124/Mol.59.4.795  0.433
2001 Marí M, Cederbaum AI. Induction of catalase, alpha, and microsomal glutathione S-transferase in CYP2E1 overexpressing HepG2 cells and protection against short-term oxidative stress Hepatology. 33: 652-661. PMID 11230746 DOI: 10.1053/Jhep.2001.22521  0.435
2001 Marí M, Wu D, Nieto N, Cederbaum AI. CYP2E1-dependent toxicity and up-regulation of antioxidant genes. Journal of Biomedical Science. 8: 52-58. PMID 11173976 DOI: 10.1007/Bf02255971  0.519
2001 Bai J, Cederbaum AI. Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against cytochrome P450 2E1-dependent toxicity in HepG2 cells. Journal of Biological Chemistry. 276: 4315-4321. PMID 11071897 DOI: 10.1074/Jbc.M008895200  0.445
2001 Casey CA, Nanji A, Cederbaum AI, Adachi M, Takahashi T. Alcoholic liver disease and apoptosis Alcoholism: Clinical and Experimental Research. 25. DOI: 10.1111/J.1530-0277.2001.Tb02373.X  0.327
2001 Wu D, Cederbaum AI. Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1. Alcoholism: Clinical and Experimental Research. 25: 619-628. DOI: 10.1111/J.1530-0277.2001.Tb02259.X  0.443
2000 Sakurai K, Stoyanovsky DA, Fujimoto Y, Cederbaum AI. Mitochondrial permeability transition induced by 1-hydroxyethyl radical. Free Radical Biology & Medicine. 28: 273-80. PMID 11281295 DOI: 10.1016/S0891-5849(99)00236-1  0.473
2000 Goasduff T, Cederbaum AI. CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90. Archives of Biochemistry and Biophysics. 379: 321-330. PMID 10898951 DOI: 10.1006/Abbi.2000.1870  0.359
2000 Bai J, Cederbaum AI. Overexpression of Catalase in the Mitochondrial or Cytosolic Compartment Increases Sensitivity of HepG2 Cells to Tumor Necrosis Factor-α-induced Apoptosis Journal of Biological Chemistry. 275: 19241-19249. PMID 10764744 DOI: 10.1074/Jbc.M000438200  0.305
2000 Marı́ M, Cederbaum AI. CYP2E1 Overexpression in HepG2 Cells Induces Glutathione Synthesis by Transcriptional Activation of γ-Glutamylcysteine Synthetase Journal of Biological Chemistry. 275: 15563-15571. PMID 10748080 DOI: 10.1074/Jbc.M907022199  0.428
2000 Wu D, Cederbaum A. Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1. Molecular and Cellular Biochemistry. 204: 157-167. PMID 10718635 DOI: 10.1023/A:1007064706101  0.423
1999 Puntarulo S, Stoyanovsky DA, Cederbaum AI. Interaction of 1-hydroxyethyl radical with antioxidant enzymes. Archives of Biochemistry and Biophysics. 372: 355-9. PMID 10600175 DOI: 10.1006/Abbi.1999.1500  0.481
1999 Goasduff T, Cederbaum AI. NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species. Archives of Biochemistry and Biophysics. 370: 258-270. PMID 10510285 DOI: 10.1006/Abbi.1999.1399  0.436
1999 Nieto N, Friedman SL, Greenwel P, Cederbaum AI. CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells. Hepatology. 30: 987-996. PMID 10498651 DOI: 10.1002/Hep.510300433  0.421
1999 Bai J, Rodriguez AM, Melendez JA, Cederbaum AI. Overexpression of catalase in cytosolic or mitochondrial compartment protects HepG2 cells against oxidative injury. The Journal of Biological Chemistry. 274: 26217-24. PMID 10473575 DOI: 10.1074/Jbc.274.37.26217  0.367
1999 Stoyanovsky DA, Cederbaum AI. Metabolism of carbon tetrachloride to trichloromethyl radical: An ESR and HPLC-EC study. Chemical Research in Toxicology. 12: 730-6. PMID 10458707 DOI: 10.1021/Tx9900371  0.372
1999 Cederbaum AI. Effects of alcohol on hepatic mitochondrial function and DNA Gastroenterology. 117: 265-269. PMID 10381938 DOI: 10.1016/S0016-5085(99)70578-0  0.304
1999 Stoyanovsky DA, Melnikov Z, Cederbaum AI. ESR and HPLC-EC analysis of the interaction of hydroxyl radical with DMSO: rapid reduction and quantification of POBN and PBN nitroxides. Analytical Chemistry. 71: 715-21. PMID 9989388 DOI: 10.1021/Ac980657R  0.328
1999 Wu D, Cederbaum AI. Ethanol-Induced Apoptosis to Stable HepG2 Cell Lines Expressing Human Cytochrome P-4502E1 Alcoholism: Clinical and Experimental Research. 23: 67-76. DOI: 10.1111/J.1530-0277.1999.Tb04025.X  0.437
1998 Sakurai K, Cederbaum AI. Oxidative Stress and Cytotoxicity Induced by Ferric-Nitrilotriacetate in HepG2 Cells That Express Cytochrome P450 2E1 Molecular Pharmacology. 54: 1024-1035. PMID 9855631 DOI: 10.1124/Mol.54.6.1024  0.473
1998 Stoyanovsky DA, Cederbaum AI. ESR and HPLC-EC analysis of ethanol oxidation to 1-hydroxyethyl radical: rapid reduction and quantification of POBN and PBN nitroxides. Free Radical Biology & Medicine. 25: 536-45. PMID 9741590 DOI: 10.1016/S0891-5849(98)00081-1  0.458
1998 Cederbaum AI. Ethanol‐related cytotoxicity catalyzed by CYP2E1‐dependent generation of reactive oxygen intermediates in transduced HepG2 cells Biofactors. 8: 93-96. PMID 9699015 DOI: 10.1002/Biof.5520080116  0.47
1998 Puntarulo S, Cederbaum AI. Production of reactive oxygen species by microsomes enriched in specific human cytochrome P450 enzymes. Free Radical Biology and Medicine. 24: 1324-1330. PMID 9626590 DOI: 10.1016/S0891-5849(97)00463-2  0.442
1998 Stoyanovsky DA, Cederbaum AI. Redox-cycling of iron ions triggers calcium release from liver microsomes. Free Radical Biology & Medicine. 24: 745-53. PMID 9586805 DOI: 10.1016/S0891-5849(97)00328-6  0.315
1998 Chen Q, Cederbaum AI. Cytotoxicity and Apoptosis Produced by Cytochrome P450 2E1 in Hep G2 Cells Molecular Pharmacology. 53: 638-648. PMID 9547353 DOI: 10.1124/Mol.53.4.638  0.391
1998 Stoyanovsky DA, Wu D, Cederbaum AI. Interaction of 1-hydroxyethyl radical with glutathione, ascorbic acid and alpha-tocopherol. Free Radical Biology & Medicine. 24: 132-8. PMID 9436622 DOI: 10.1016/S0891-5849(97)00205-0  0.403
1998 Chen Q, Galleano M, Cederbaum AI. Cytotoxicity and apoptosis produced by arachidonic acid in HepG2 cells overexpressing human cytochrome P-4502E1. Alcoholism: Clinical and Experimental Research. 22: 782-784. DOI: 10.1111/J.1530-0277.1998.Tb03868.X  0.358
1997 Chen Q, Cederbaum AI. Menadione cytotoxicity to Hep G2 cells and protection by activation of nuclear factor-kappaB. Molecular Pharmacology. 52: 648-657. PMID 9380028 DOI: 10.1124/Mol.52.4.648  0.38
1997 Gergel D, Cederbaum AI. Interaction of Nitric Oxide with 2-Thio-5-nitrobenzoic Acid: Implications for the Determination of Free Sulfhydryl Groups by Ellman's Reagent Archives of Biochemistry and Biophysics. 347: 282-288. PMID 9367537 DOI: 10.1006/Abbi.1997.0352  0.37
1997 Wu D, Ramin SA, Cederbaum AI. Effect Of Pyridine On The Expression Of Cytochrome P450 Isozymes In Primary Rat Hepatocyte Culture Molecular and Cellular Biochemistry. 173: 103-111. PMID 9278260 DOI: 10.1023/A:1006831811622  0.332
1997 Chen Q, Galleano M, Cederbaum AI. Cytotoxicity and apoptosis produced by arachidonic acid in Hep G2 cells overexpressing human cytochrome P4502E1. Journal of Biological Chemistry. 272: 14532-14541. PMID 9169410 DOI: 10.1074/Jbc.272.23.14532  0.37
1997 Yang M, Cederbaum AI. Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1. Archives of Biochemistry and Biophysics. 341: 25-33. PMID 9143349 DOI: 10.1006/Abbi.1997.9907  0.361
1997 Puntarulo S, Cederbaum AI. Inhibition of ferritin-stimulated microsomal production of reactive oxygen intermediates by nitric oxide. Archives of Biochemistry and Biophysics. 340: 19-26. PMID 9126272 DOI: 10.1006/Abbi.1997.9890  0.493
1997 Gergel D, Mišı́k V, Riesz P, Cederbaum AI. Inhibition of Rat and Human Cytochrome P4502E1 Catalytic Activity and Reactive Oxygen Radical Formation by Nitric Oxide Archives of Biochemistry and Biophysics. 337: 239-250. PMID 9016819 DOI: 10.1006/Abbi.1996.9765  0.523
1997 Rao DNR, Cederbaum AI. A comparative study of the redox-cycling of a quinone (rifamycin S) and a quinonimine (rifabutin) antibiotic by rat liver microsomes. Free Radical Biology and Medicine. 22: 439-446. PMID 8981035 DOI: 10.1016/S0891-5849(96)00335-8  0.416
1997 Yang M, Cederbaum AI. Glycerol Increases Content and Activity of Human Cytochrome P-4502E1 in a Transduced HepG2 Cell Line by Protein Stabilization Alcoholism: Clinical and Experimental Research. 21: 340-347. DOI: 10.1111/J.1530-0277.1997.Tb03770.X  0.402
1996 Gergel D, Cederbaum AI. Inhibition Of The Catalytic Activity Of Alcohol Dehydrogenase By Nitric Oxide Is Associated With S Nitrosylation And The Release Of Zinc Biochemistry. 35: 16186-16194. PMID 8973191 DOI: 10.1021/Bi962043R  0.507
1996 Stoyanovsky DA, Cederbaum AI. Thiol oxidation and cytochrome P450-dependent metabolism of CCl4 triggers Ca2+ release from liver microsomes. Biochemistry. 35: 15839-45. PMID 8961948 DOI: 10.1021/Bi961295P  0.309
1996 Song BJ, Cederbaum AI. Ethanol-inducible cytochrome P450 (CYP2E1): biochemistry, molecular biology and clinical relevance: 1996 update. Alcoholism: Clinical and Experimental Research. 20. PMID 8947253 DOI: 10.1111/J.1530-0277.1996.Tb01764.X  0.367
1996 Yang M, Cederbaum AI. Role of the Proteasome Complex in Degradation of Human CYP2E1 in Transfected HepG2 Cells Biochemical and Biophysical Research Communications. 226: 711-716. PMID 8831679 DOI: 10.1006/Bbrc.1996.1418  0.332
1996 Kukiełka E, Cederbaum AI. Ferritin Stimulation of Lipid Peroxidation by Microsomes after Chronic Ethanol Treatment: Role of Cytochrome P4502E1 Archives of Biochemistry and Biophysics. 332: 121-127. PMID 8806716 DOI: 10.1006/Abbi.1996.0323  0.473
1996 Wu D, Cederbaum AI. Ethanol Cytotoxicity to a Transfected HepG2 Cell Line Expressing Human Cytochrome P4502E1 Journal of Biological Chemistry. 271: 23914-23919. PMID 8798623 DOI: 10.1074/Jbc.271.39.23914  0.433
1996 Yang M, Cederbaum AI. Interaction of Ferric Complexes with NADH–Cytochrome b5 Reductase and Cytochrome b5: Lipid Peroxidation, H2O2Generation, and Ferric Reduction Archives of Biochemistry and Biophysics. 331: 69-78. PMID 8660685 DOI: 10.1006/Abbi.1996.0284  0.37
1996 Puntarulo S, Cederbaum AI. Role of cytochrome P-450 in the stimulation of microsomal production of reactive oxygen species by ferritin. Biochimica Et Biophysica Acta. 1289: 238-246. PMID 8600980 DOI: 10.1016/0304-4165(95)00157-3  0.433
1996 Rao DNR, Cederbaum AI. Generation of reactive oxygen species by the redox cycling of nitroprusside. Biochimica Et Biophysica Acta. 1289: 195-202. PMID 8600973 DOI: 10.1016/0304-4165(95)00158-1  0.446
1995 Kringstein P, Cederbaum AI. Boldine prevents human liver microsomal lipid peroxidation and inactivation of cytochrome P4502E1 Free Radical Biology and Medicine. 18: 559-563. PMID 9101247 DOI: 10.1016/0891-5849(94)E0138-9  0.418
1995 Yang M, Cederbaum AI. Role of Cytochrome b5in NADH-Dependent Microsomal Reduction of Ferric Complexes, Lipid Peroxidation, and Hydrogen Peroxide Generation Archives of Biochemistry and Biophysics. 324: 282-292. PMID 8554320 DOI: 10.1006/Abbi.1995.0041  0.335
1995 Kukiełka E, Cederbaum AI. Stimulation of NADH-dependent microsomal DNA strand cleavage by rifamycin SV. Biochemical Journal. 307: 361-367. PMID 7733870 DOI: 10.1042/Bj3070361  0.383
1995 Gergel D, Misík V, Ondrias K, Cederbaum AI. Increased cytotoxicity of 3-morpholinosydnonimine to HepG2 cells in the presence of superoxide dismutase. Role of hydrogen peroxide and iron. The Journal of Biological Chemistry. 270: 20922-9. PMID 7673115 DOI: 10.1074/Jbc.270.36.20922  0.389
1995 Rao DNR, Cederbaum AI. Production of Nitric Oxide and Other Iron-Containing Metabolites during the Reductive Metabolism of Nitroprusside by Microsomes and by Thiols Archives of Biochemistry and Biophysics. 321: 363-371. PMID 7646061 DOI: 10.1006/Abbi.1995.1406  0.316
1995 Kukielka E, Cederbaum AI. Increased oxidation of ethylene glycol to formaldehyde by microsomes after ethanol treatment: role of oxygen radicals and cytochrome P450. Toxicology Letters. 78: 9-15. PMID 7604403 DOI: 10.1016/0378-4274(94)03225-V  0.505
1995 Kukielka E, Cederbaum AI. Increased production of hydroxyl radical by pericentral microsomes compared to periportal microsomes after pyrazole induction of cytochrome P4502E1. Biochemical and Biophysical Research Communications. 215: 698-705. PMID 7488011 DOI: 10.1006/Bbrc.1995.2520  0.459
1994 Kukielka E, Cederbaum AI. Ferritin stimulation of hydroxyl radical production by rat liver nuclei. Archives of Biochemistry and Biophysics. 308: 70-77. PMID 8311476 DOI: 10.1006/Abbi.1994.1010  0.468
1994 Puntarulo S, Cederbaum AI. Ferritin-dependent inactivation of microsomal glucose-6-phosphatase. Biochimica Et Biophysica Acta. 1200: 41-47. PMID 8186231 DOI: 10.1016/0304-4165(94)90025-6  0.402
1994 Kukielka E, Dicker E, Cederbaum AI. Increased Production of Reactive Oxygen Species by Rat Liver Mitochondria After Chronic Ethanol Treatment Archives of Biochemistry and Biophysics. 309: 377-386. PMID 8135551 DOI: 10.1006/Abbi.1994.1127  0.511
1994 Carroccio A, Wu DF, Cederbaum AI. Ethanol increases content and activity of human cytochrome P4502E1 in a transduced HepG2 cell line. Biochemical and Biophysical Research Communications. 203: 727-733. PMID 8074729 DOI: 10.1006/Bbrc.1994.2242  0.472
1994 Rashba-Step J, Step E, Turro NJ, Cederbaum AI. Oxidation of glycerol to formaldehyde by microsomes: are glycerol radicals produced in the reaction pathway? Biochemistry. 33: 9504-10. PMID 8068625 DOI: 10.1021/Bi00198A016  0.434
1994 Yang M, Cederbaum AI. Fractionation of liver microsomes with polyethylene glycol and purification of NADH-cytochrome b5 oxidoreductase and cytochrome b5. Archives of Biochemistry and Biophysics. 315: 438-444. PMID 7986089 DOI: 10.1006/Abbi.1994.1522  0.312
1994 Kukielka E, Cederbaum AI. DNA strand cleavage as a sensitive assay for the production of hydroxyl radicals by microsomes: role of cytochrome P4502E1 in the increased activity after ethanol treatment Biochemical Journal. 302: 773-779. PMID 7945202 DOI: 10.1042/Bj3020773  0.447
1993 Puntarulo S, Cederbaum AI. Stimulation of microsomal chemiluminescence by ferritin. Biochimica Et Biophysica Acta. 1157: 1-8. PMID 8499475 DOI: 10.1016/0304-4165(93)90071-F  0.386
1993 Wu D, Cederbaum AI. Combined effects of streptozotocin-induced diabetes plus 4-methylpyrazole treatment on rat liver cytochrome P4502E1. Archives of Biochemistry and Biophysics. 302: 175-182. PMID 8470894 DOI: 10.1006/Abbi.1993.1196  0.327
1993 Rashba-Step J, Turro NJ, Cederbaum AI. Increased NADPH- and NADH-dependent production of superoxide and hydroxyl radical by microsomes after chronic ethanol treatment. Archives of Biochemistry and Biophysics. 300: 401-8. PMID 8380969 DOI: 10.1006/Abbi.1993.1054  0.467
1993 Rashba-Step J, Turro NJ, Cederbaum AI. ESR studies on the production of reactive oxygen intermediates by rat liver microsomes in the presence of NADPH or NADH. Archives of Biochemistry and Biophysics. 300: 391-400. PMID 8380968 DOI: 10.1006/Abbi.1993.1053  0.446
1993 Clejan LA, Cederbaum AI. Stimulation by paraquat of microsomal and cytochrome P-450-dependent oxidation of glycerol to formaldehyde Biochemical Journal. 295: 781-786. PMID 8240292 DOI: 10.1042/Bj2950781  0.447
1993 Dai Y, Rashba-Step J, Cederbaum AI. Stable expression of human cytochrome P4502E1 in HepG2 cells: characterization of catalytic activities and production of reactive oxygen intermediates. Biochemistry. 32: 6928-6937. PMID 7687464 DOI: 10.1021/Bi00078A017  0.449
1993 Kukielka E, Cederbaum AI. Increased cleavage of ethylene glycol to formaldehyde by oxidants produced from cytochrome P4502E1 Free Radical Biology and Medicine. 15: 541. DOI: 10.1016/0891-5849(93)90451-Y  0.436
1993 Rashba-Step J, Clejan L, Cederbaum AI. Effect of inhibitors and substrates on oxygen radical production by cytochrome P450 Free Radical Biology and Medicine. 15: 524. DOI: 10.1016/0891-5849(93)90387-A  0.36
1992 Winters DK, Cederbaum AI. Time course characterization of the induction of cytochrome P-450 2E1 by pyrazole and 4-methylpyrazole. Biochimica Et Biophysica Acta. 1117: 15-24. PMID 1627587 DOI: 10.1016/0304-4165(92)90156-O  0.326
1992 Wu D, Cederbaum AI. Presence of functionally active cytochrome P-450IIE1 in the plasma membrane of rat hepatocytes Hepatology. 15: 515-524. PMID 1544634 DOI: 10.1002/Hep.1840150326  0.334
1992 Clejan LA, Cederbaum AI. Role of cytochrome P450 in the oxidation of glycerol by reconstituted systems and microsomes. The Faseb Journal. 6: 765-770. PMID 1537467 DOI: 10.1096/Fasebj.6.2.1537467  0.485
1992 Clejan LA, Cederbaum AI. Structural determinants for alcohol substrates to be oxidized to formaldehyde by rat liver microsomes. Archives of Biochemistry and Biophysics. 298: 105-113. PMID 1524418 DOI: 10.1016/0003-9861(92)90100-B  0.475
1992 Winters DK, Cederbaum AI. Expression of a catalytically active human cytochrome P-4502E1 in Escherichia coli Bba - General Subjects. 1156: 43-49. PMID 1472537 DOI: 10.1016/0304-4165(92)90093-A  0.369
1992 Cederbaum AI, Ukielka EK, Speiskyf H. Inhibition of rat liver microsomal lipid peroxidation by boldine Biochemical Pharmacology. 44: 1765-1772. PMID 1333206 DOI: 10.1016/0006-2952(92)90070-Y  0.47
1992 Puntarulo S, Cederbaum AI. Effect of phenobarbital and 3-methylcholanthrene treatment on NADPH- and NADH-dependent production of reactive oxygen intermediates by rat liver nuclei. Biochimica Et Biophysica Acta. 1116: 17-23. PMID 1311603 DOI: 10.1016/0304-4165(92)90122-B  0.427
1992 Dicker E, Cederbaum AI. Increased NADH-dependent production of reactive oxygen intermediates by microsomes after chronic ethanol consumption: comparisons with NADPH. Archives of Biochemistry and Biophysics. 293: 274-280. PMID 1311163 DOI: 10.1016/0003-9861(92)90395-D  0.505
1992 Kukiełka E, Cederbaum AI. The effect of chronic ethanol consumption on NADH- and NADPH-dependent generation of reactive oxygen intermediates by isolated rat liver nuclei. Alcohol and Alcoholism. 27: 233-239. DOI: 10.1093/Oxfordjournals.Alcalc.A045235  0.493
1992 Winters DK, Cederbaum AI. The content and activity of cytochrome P450 2E1 in liver microsomes from alcohol-preferring and non-preferring rats. Alcohol and Alcoholism. 27: 63-70. DOI: 10.1093/Oxfordjournals.Alcalc.A045195  0.422
1991 Puntarulo S, Cederbaum AI. Inhibition of the oxidation of hydroxyl radical scavenging agents after alkaline phosphatase treatment of rat liver microsomes. Biochimica Et Biophysica Acta. 1074: 12-18. PMID 1904277 DOI: 10.1016/0304-4165(91)90031-B  0.413
1991 Clejan LA, Cederbaum AI. Role of iron, hydrogen peroxide and reactive oxygen species in microsomal oxidation of glycerol to formaldehyde Archives of Biochemistry and Biophysics. 285: 83-89. PMID 1846735 DOI: 10.1016/0003-9861(91)90331-C  0.459
1991 Dicker E, Cederbaum AI. Increased oxidation of dimethylnitrosamine in pericentral microsomes after pyrazole induction of cytochrome P-4502E1. Alcoholism: Clinical and Experimental Research. 15: 1072-1076. PMID 1686370 DOI: 10.1111/J.1530-0277.1991.Tb05214.X  0.486
1991 Dicker E, McHugh T, Cederbaum AI. Increased catalytic activity of cytochrome P-450IIE1 in pericentral hepatocytes compared to periportal hepatocytes isolated from pyrazole-treated rats Bba - General Subjects. 1073: 316-323. PMID 1672609 DOI: 10.1016/0304-4165(91)90137-6  0.464
1991 Dicker E, Cederbaum AI. NADH-dependent generation of reactive oxygen species by microsomes in the presence of iron and redox cycling agents. Biochemical Pharmacology. 42: 529-535. PMID 1650215 DOI: 10.1016/0006-2952(91)90315-V  0.502
1990 Clejan LA, Cederbaum AI. Oxidation of pyrazole by reconstituted systems containing cytochrome P-450 IIE1 Biochimica Et Biophysica Acta. 1034: 233-237. PMID 2354195 DOI: 10.1016/0304-4165(90)90082-8  0.485
1990 Winters DK, Cederbaum AI. Oxidation of glycerol to formaldehyde by rat liver microsomes. Effects of cytochrome P-450 inducing agents Biochemical Pharmacology. 39: 697-705. PMID 2306278 DOI: 10.1016/0006-2952(90)90148-E  0.482
1990 Kukiełka E, Cederbaum AI. NADPH- and NADH-dependent oxygen radical generation by rat liver nuclei in the presence of redox cycling agents and iron. Archives of Biochemistry and Biophysics. 283: 326-333. PMID 2275546 DOI: 10.1016/0003-9861(90)90650-N  0.463
1990 Wu DF, Clejan L, Potter B, Cederbaum AI. Rapid decrease of cytochrome P-450IIE1 in primary hepatocyte culture and its maintenance by added 4-methylpyrazole. Hepatology. 12: 1379-1389. PMID 2258154 DOI: 10.1002/Hep.1840120620  0.327
1990 Dicker E, McHugh T, Cederbaum AI. Increased oxidation of p-nitrophenol and aniline by intact hepatocytes isolated from pyrazole-treated rats Bba - General Subjects. 1035: 249-256. PMID 2207123 DOI: 10.1016/0304-4165(90)90086-C  0.433
1990 Dicker E, Cederbaum AI. Generation of Reactive Oxygen Species and Reduction of Ferric Chelates by Microsomes in the Presence of a Reconstituted System Containing Ethanol, NAD+ and Alcohol Dehydrogenase Alcoholism: Clinical and Experimental Research. 14: 238-244. PMID 2161619 DOI: 10.1111/J.1530-0277.1990.Tb00479.X  0.548
1989 Kukiełka E, Puntarulo S, Cederbaum AI. Interaction of ferric complexes with rat liver nuclei to catalyze NADH-and NADPH-Dependent production of oxygen radicals. Archives of Biochemistry and Biophysics. 273: 319-330. PMID 2774554 DOI: 10.1016/0003-9861(89)90490-6  0.479
1989 Cederbaum AI. Introduction: role of lipid peroxidation and oxidative stress in alcohol toxicity Free Radical Biology and Medicine. 7: 537-539. PMID 2693222 DOI: 10.1016/0891-5849(89)90029-4  0.396
1989 Kukiełka E, Cederbaum AI. NADH-dependent microsomal interaction with ferric complexes and production of reactive oxygen intermediates. Archives of Biochemistry and Biophysics. 275: 540-550. PMID 2556968 DOI: 10.1016/0003-9861(89)90400-1  0.497
1989 Puntarulo S, Turrens JF, Cederbaum AI. Oxygen-concentration dependence of microsomal chemiluminescence Free Radical Biology and Medicine. 7: 269-273. PMID 2550333 DOI: 10.1016/0891-5849(89)90134-2  0.339
1989 Puntarulo S, Cederbaum AI. Interactions between paraquat and ferric complexes in the microsomal generation of oxygen radicals. Biochemical Pharmacology. 38: 2911-2918. PMID 2550014 DOI: 10.1016/0006-2952(89)90449-8  0.439
1989 Puntarulo S, Cederbaum AI. Chemiluminescence from Acetaldehyde Oxidation by Xanthine Oxidase Involves Generation of and Interactions with Hydroxyl Radicals Alcoholism: Clinical and Experimental Research. 13: 84-90. PMID 2538093 DOI: 10.1111/J.1530-0277.1989.Tb00288.X  0.453
1989 Puntarulo S, Cederbaum AI. Temperature dependence of the microsomal oxidation of ethanol by cytochrome P450 and hydroxyl radical-dependent reactions. Archives of Biochemistry and Biophysics. 269: 569-575. PMID 2537602 DOI: 10.1016/0003-9861(89)90142-2  0.484
1989 Feierman DE, Cederbaum AI. Role of cytochrome P-450 IIE1 and catalase in the oxidation of acetonitrile to cyanide. Chemical Research in Toxicology. 2: 359-366. PMID 2519724 DOI: 10.1021/Tx00012A002  0.488
1989 Clejan L, Cederbaum AI. Synergistic interactions between NADPH-cytochrome P-450 reductase, paraquat, and iron in the generation of active oxygen radicals. Biochemical Pharmacology. 38: 1779-1786. PMID 2500125 DOI: 10.1016/0006-2952(89)90412-7  0.457
1989 Puntarulo S, Cederbaum AI. Vitamin E Prevents NADPH-Dependent but not NADH-Dependent Chemoluminescence by Isolated Rat Liver Nuclei Annals of the New York Academy of Sciences. 570: 503-505. DOI: 10.1111/J.1749-6632.1989.Tb14969.X  0.33
1988 Puntarulo S, Cederbaum AI. Effect of oxygen concentration on microsomal oxidation of ethanol and generation of oxygen radicals. Biochemical Journal. 251: 787-794. PMID 3415646 DOI: 10.1042/Bj2510787  0.435
1988 Winters DK, Clejan LA, Cederbaum AI. Oxidation of glycerol to formaldehyde by rat liver microsomes. Biochemical and Biophysical Research Communications. 153: 612-7. PMID 3382392 DOI: 10.1016/S0006-291X(88)81139-2  0.469
1988 Puntarulo S, Cederbaum AI. Oxidation of pyrazole to 4-hydroxypyrazole by intact rat hepatocytes. Biochemical Pharmacology. 37: 1555-1561. PMID 3358785 DOI: 10.1016/0006-2952(88)90018-4  0.506
1988 Puntarulo S, Cederbaum AI. Increased NADPH-dependent Chemiluminescence by Microsomes After Chronic Ethanol Consumption Archives of Biochemistry and Biophysics. 266: 435-445. PMID 3190238 DOI: 10.1016/0003-9861(88)90275-5  0.446
1988 Dicker E, Cederbaum AI. Increased oxygen radical-dependent inactivation of metabolic enzymes by liver microsomes after chronic ethanol consumption. The Faseb Journal. 2: 2901-2906. PMID 3169467 DOI: 10.1096/Fasebj.2.13.3169467  0.464
1988 Puntarulo S, Cederbaum AI. Increased microsomal interaction with iron and oxygen radical generation after chronic acetone treatment. Biochimica Et Biophysica Acta. 964: 46-52. PMID 3120790 DOI: 10.1016/0304-4165(88)90065-7  0.463
1988 Puntarulo S, Cederbaum AI. Comparison of the ability of ferric complexes to catalyze microsomal chemiluminescence, lipid peroxidation, and hydroxyl radical generation Archives of Biochemistry and Biophysics. 264: 482-491. PMID 2840858 DOI: 10.1016/0003-9861(88)90313-X  0.426
1987 Feierman DE, Cederbaum AI. Increased sensitivity of the microsomal oxidation of ethanol to inhibition by pyrazole and 4-methylpyrazole after chronic ethanol treatment Biochemical Pharmacology. 36: 3277-3283. PMID 3663241 DOI: 10.1016/0006-2952(87)90645-9  0.466
1987 Cederbaum AI. Microsomal generation of hydroxyl radicals: its role in microsomal ethanol oxidizing system (MEOS) activity and requirement for iron. Annals of the New York Academy of Sciences. 492: 35-49. PMID 3037964 DOI: 10.1111/J.1749-6632.1987.Tb48651.X  0.468
1987 Puntarulo S, Cederbaum AI. Production of 4-hydroxypyrazole from the interaction of the alcohol dehydrogenase inhibitor pyrazole with hydroxyl radical. Archives of Biochemistry and Biophysics. 255: 217-225. PMID 3036002 DOI: 10.1016/0003-9861(87)90388-2  0.466
1987 Puntarulo S, Cederbaum AI. Chemiluminescence studies on the generation of oxygen radicals from the interaction of NADPH-cytochrome P-450 reductase with iron. Archives of Biochemistry and Biophysics. 258: 510-518. PMID 2823718 DOI: 10.1016/0003-9861(87)90373-0  0.424
1987 Dicker E, Cederbaum AI. Hydroxyl radical generation by microsomes after chronic ethanol consumption. Alcoholism: Clinical and Experimental Research. 11: 309-314. PMID 2820260 DOI: 10.1111/J.1530-0277.1987.Tb01314.X  0.473
1987 Dicker E, Cederbaum AI. In-Vivo and In-Vitro Inhibition of the Low Km Aldehyde Dehydrogenase by Diethylmaleate and Phorone Annals of the New York Academy of Sciences. 492: 63-65. DOI: 10.1111/J.1749-6632.1987.Tb48653.X  0.303
1987 Dicker E, Cederbaum AI. Pathways of Metabolism of Formaldehyde Produced from the Oxidation of Aminopyrine by Intact Rat Hepatocytes Annals of the New York Academy of Sciences. 494: 332-335. DOI: 10.1111/J.1749-6632.1987.Tb29564.X  0.379
1987 Beloqui O, Cederbaum AI. Microsomal Lipid Peroxidation and Hydroxyl Radical Production Involve Different Oxygen Radical Species Annals of the New York Academy of Sciences. 494: 184-186. DOI: 10.1111/J.1749-6632.1987.Tb29517.X  0.356
1986 Dicker E, Cederbaum AI. Inhibition of the low-Km mitochondrial aldehyde dehydrogenase by diethyl maleate and phorone in vivo and in vitro Implications for formaldehyde metabolism Biochemical Journal. 240: 821-827. PMID 3827870 DOI: 10.1042/Bj2400821  0.453
1986 Feierman DE, Cederbaum AI. Inhibition of microsomal oxidation of ethanol by pyrazole and 4-methylpyrazole in vitro. Increased effectiveness after induction by pyrazole and 4-methylpyrazole. Biochemical Journal. 239: 671-677. PMID 3827819 DOI: 10.1042/Bj2390671  0.488
1986 Krikun G, Cederbaum AI. Effect of chronic ethanol consumption on microsomal lipid peroxidation. Role of iron and comparison between controls. Febs Letters. 208: 292-296. PMID 3780968 DOI: 10.1016/0014-5793(86)81035-3  0.397
1986 Winston GW, Eibschutz OM, Strekas T, Cederbaum AI. Complex-formation and reduction of ferric iron by 2-oxo-4-thiomethylbutyric acid, and the production of hydroxyl radicals. The Biochemical Journal. 235: 521-9. PMID 3741403 DOI: 10.1042/Bj2350521  0.349
1986 Dicker E, Cederbaum AI. Inhibition of CO2 production from aminopyrine or methanol by cyanamide or crotonaldehyde and the role of mitochondrial aldehyde dehydrogenase in formaldehyde oxidation. Biochimica Et Biophysica Acta. 883: 91-97. PMID 3089300 DOI: 10.1016/0304-4165(86)90139-X  0.461
1986 Winston GW, Cederbaum AI. Differential effects of the cytochrome P-450/reductase ratio on the oxidation of ethanol and the hydroxyl radical scavenging agent 2-keto-4-thiomethylbutyric acid (KMBA). Biochemical Pharmacology. 35: 4053-8. PMID 3022748 DOI: 10.1016/0006-2952(86)90027-4  0.496
1986 Beloqui O, Cederbaum AI. Prevention of microsomal production of hydroxyl radicals, but not lipid peroxidation, by the glutathione-glutathione peroxidase system. Biochemical Pharmacology. 35: 2663-2669. PMID 3017360 DOI: 10.1016/0006-2952(86)90172-3  0.483
1986 Beloqui O, Cederbaum AI. Microsomal Interactions between Iron, Paraquat, and Menadione on Hydroxyl Radical Formation, Alcohol Oxidation, and Drug Metabolism Annals of the New York Academy of Sciences. 463: 259-261. DOI: 10.1111/J.1749-6632.1986.Tb21564.X  0.395
1986 Feierman DE, Cederbaum AI. Increased Content of Cytochrome P‐450 and Microsomal Alcohol Oxidation after 4‐Methylpyrazole Treatment Annals of the New York Academy of Sciences. 463: 96-98. DOI: 10.1111/J.1749-6632.1986.Tb21511.X  0.403
1985 Cederbaum AI, Dicker E. Inhibition of the peroxidatic activity of catalase towards alcohols by the aldehyde dehydrogenase inhibitor cyanamide Toxicology Letters. 29: 107-114. PMID 4089878 DOI: 10.1016/0378-4274(85)90030-X  0.419
1985 Dicker E, Cederbaum AI. Inhibition of mitochondrial aldehyde dehydrogenase and acetaldehyde oxidation by the glutathione-depleting agents diethylmaleate and phorone. Biochimica Et Biophysica Acta. 843: 107-113. PMID 4063385 DOI: 10.1016/0304-4165(85)90056-X  0.475
1985 Feierman DE, Cederbaum AI. Increased content of cytochrome P-450 and 4-methylpyrazole binding spectrum after 4-methylpyrazole treatment Biochemical and Biophysical Research Communications. 126: 1076-1081. PMID 3977903 DOI: 10.1016/0006-291X(85)90295-5  0.399
1985 Feierman DE, Cederbaum AI. Interaction of pyrazole and 4-methylpyrazole with hepatic microsomes: effect on cytochrome P-450 content, microsomal oxidation of alcohols, and binding spectra Alcoholism: Clinical and Experimental Research. 9: 421-428. PMID 3933374 DOI: 10.1111/J.1530-0277.1985.Tb05576.X  0.444
1985 Feierman DE, Cederbaum AI. Ethylene production from α-keto-4-thiomethylbutyric acid by isolated rat liver cells, suspension medium, and perfusates in the absence and presence of iron Journal of Free Radicals in Biology & Medicine. 1: 155-162. PMID 3013975 DOI: 10.1016/0748-5514(85)90020-0  0.426
1985 Beloqui O, Cederbaum AI. Microsomal interactions between iron, paraquat, and menadione: effect on hydroxyl radical production and alcohol oxidation. Archives of Biochemistry and Biophysics. 242: 187-196. PMID 2996429 DOI: 10.1016/0003-9861(85)90492-8  0.531
1985 Krikun G, Cederbaum AI. Evaluation of microsomal pathways of oxidation of alcohols and hydroxyl radical scavenging agents with carbon monoxide and cobalt protoporphyrin IX. Biochemical Pharmacology. 34: 2929-2935. PMID 2992522 DOI: 10.1016/0006-2952(85)90018-8  0.466
1985 Feierman DE, Winston GW, Cederbaum AI. Ethanol oxidation by hydroxyl radicals: role of iron chelates, superoxide, and hydrogen peroxide. Alcoholism, Clinical and Experimental Research. 9: 95-102. PMID 2988364 DOI: 10.1111/J.1530-0277.1985.Tb05525.X  0.439
1984 Dicker E, Cederbaum AI. Effect of acetaldehyde and cyanamide on the metabolism of formaldehyde by hepatocytes, mitochondria, and soluble supernatant from rat liver☆ Archives of Biochemistry and Biophysics. 232: 179-188. PMID 6742849 DOI: 10.1016/0003-9861(84)90533-2  0.46
1984 Dicker E, Cederbaum AI. Inhibition of the oxidation of acetaldehyde and formaldehyde by hepatocytes and mitochondria by crotonaldehyde Archives of Biochemistry and Biophysics. 234: 187-196. PMID 6486817 DOI: 10.1016/0003-9861(84)90340-0  0.481
1984 Krikun G, Cederbaum AI. Increased microsomal oxidation of alcohols after pyrazole treatment and its similarities to the induction by ethanol consumption. Biochimica Et Biophysica Acta. 801: 131-137. PMID 6466709 DOI: 10.1016/0304-4165(84)90221-6  0.488
1984 Winston GW, Feierman DE, Cederbaum AI. The role of iron chelates in hydroxyl radical production by rat liver microsomes, NADPH-cytochrome P-450 reductase and xanthine oxidase. Archives of Biochemistry and Biophysics. 232: 378-90. PMID 6331321 DOI: 10.1016/0003-9861(84)90553-8  0.42
1984 Cederbaum AI, Cohen G. [68] Microsomal oxidant radical production and ethanol oxidation Methods in Enzymology. 105: 516-522. PMID 6328202 DOI: 10.1016/S0076-6879(84)05071-0  0.514
1984 Krikun G, Cederbaum AI. Stereochemical studies on the cytochrome P-450 and hydroxyl radical dependent pathways of 2-butanol oxidation by microsomes from chow-fed, phenobarbital-treated, and ethanol-treated rats Biochemistry. 23: 5489-5494. PMID 6095901 DOI: 10.1021/Bi00318A017  0.525
1984 Krikun G, Lieber CS, Cederbaum AI. Increased microsomal oxidation of ethanol by cytochrome P-450 and hydroxyl radical-dependent pathways after chronic ethanol consumption☆ Biochemical Pharmacology. 33: 3306-3309. PMID 6091674 DOI: 10.1016/0006-2952(84)90097-2  0.457
1984 WINSTON GW, EIBSCHUTZ OM, CEDERBAUM AI. Formation of an Iron-Methiolbutyric Acid (FeKTBA) Complex: Interaction with Hydrogen Peroxide and Production of Oxygen Radicals Annals of the New York Academy of Sciences. 435: 582-584. DOI: 10.1111/J.1749-6632.1984.Tb13890.X  0.333
1984 Krikun G, Cederbaum AI. Increased Cytochrome P-450 Dependent Oxidation of Alcohols after Pyrazole Treatment: Similarities to the Induction by Chronic Ethanol Consumption Annals of the New York Academy of Sciences. 435: 167-169. DOI: 10.1111/J.1749-6632.1984.Tb13760.X  0.451
1983 Klein SM, Cohen G, Lieber CS, Cederbaum AI. Increased microsomal oxidation of hydroxyl radical scavenging agents and ethanol after chronic consumption of ethanol. Archives of Biochemistry and Biophysics. 223: 425-32. PMID 6683096 DOI: 10.1016/0003-9861(83)90606-9  0.511
1983 Feierman DE, Cederbaum AI. The effect of EDTA and iron on the oxidation of hydroxyl radical scavenging agents and ethanol by rat liver microsomes. Biochemical and Biophysical Research Communications. 116: 765-770. PMID 6418168 DOI: 10.1016/0006-291X(83)90590-9  0.495
1983 Winston GW, Harvey W, Berl L, Cederbaum AI. The generation of hydroxyl and alkoxyl radicals from the interaction of ferrous bipyridyl with peroxides. The Biochemical Journal. 216: 415-21. PMID 6318737 DOI: 10.1042/Bj2160415  0.481
1983 Cederbaum AI, Qureshi A, Cohen G. Production of formaldehyde and acetone by hydroxyl-radical generating systems during the metabolism of tertiary butyl alcohol Biochemical Pharmacology. 32: 3517-3524. PMID 6316986 DOI: 10.1016/0006-2952(83)90297-6  0.404
1983 Cederbaum AI. Organic hydroperoxide-dependent oxidation of ethanol by microsomes: Lack of a role for free hydroxyl radicals Archives of Biochemistry and Biophysics. 227: 329-338. PMID 6314910 DOI: 10.1016/0003-9861(83)90377-6  0.498
1983 Winston GW, Cederbaum AI. Evidence for two ethanol oxidizing pathways in reconstituted mixed-function oxidase systems. Pharmacology, Biochemistry, and Behavior. 189-94. PMID 6314373 DOI: 10.1016/0091-3057(83)90170-3  0.514
1983 Cederbaum AI, Dicker E. Inhibition of microsomal oxidation of alcohols and of hydroxyl-radical-scavenging agents by the iron-chelating agent desferrioxamine Biochemical Journal. 210: 107-113. PMID 6303308 DOI: 10.1042/Bj2100107  0.52
1982 Dicker E, Cederbaum A. Evaluation of a role of acetaldehyde in the mechanism of inhibition of p-nitroanisole O-demethylation in isolated hepatocytes by ethanol. Archives of Biochemistry and Biophysics. 217: 441-451. PMID 7138016 DOI: 10.1016/0003-9861(82)90522-7  0.459
1982 Cederbaum AI, Dicker E. Evaluation of the Role of Acetaldehyde in the Actions of Ethanol on Gluconeogenesis by Comparison with the Effects of Crotonol and Crotonaldehyde Alcoholism: Clinical and Experimental Research. 6: 100-109. PMID 7041677 DOI: 10.1111/J.1530-0277.1982.Tb05387.X  0.489
1982 Winston GW, Cederbaum AI. Oxidative decarboxylation of benzoate to carbon dioxide by rat liver microsomes: a probe for oxygen radical production during microsomal electron transfer. Biochemistry. 21: 4265-70. PMID 6289875 DOI: 10.1021/Bi00261A013  0.395
1982 Winston GW, Cederbaum AI. A correlation between hydroxyl radical generation and ethanol oxidation by liver, lung and kidney microsomes. Biochemical Pharmacology. 31: 2031-7. PMID 6288048 DOI: 10.1016/0006-2952(82)90417-8  0.504
1982 Cederbaum AI, Berl L. Pyrazole and 4-methylpyrazole inhibit oxidation of ethanol and dimethyl sulfoxide by hydroxyl radicals generated from ascorbate, xanthine oxidase, and rat liver microsomes☆ Archives of Biochemistry and Biophysics. 216: 530-543. PMID 6287938 DOI: 10.1016/0003-9861(82)90242-9  0.524
1982 Cederbaum AI, Qureshi A. Role of catalase and hydroxyl radicals in the oxidation of methanol by rat liver microsomes Biochemical Pharmacology. 31: 329-335. PMID 6280725 DOI: 10.1016/0006-2952(82)90179-4  0.5
1981 Cederbaum AI, Dicker E. Effect of cyanamide on the metabolism of ethanol and acetaldehyde and on gluconeogenesis by isolated rat hepatocytes. Biochemical Pharmacology. 30: 3079-3088. PMID 7337724 DOI: 10.1016/0006-2952(81)90496-2  0.49
1981 Klein SM, Cohen G, Cederbaum AI. Production of formaldehyde during metabolism of dimethyl sulfoxide by hydroxyl radical generating systems. Biochemistry. 20: 6006-12. PMID 6272833 DOI: 10.1021/Bi00524A013  0.308
1981 Cederbaum AI, Qureshi A, Messenger P. Oxidation of isopropanol by rat liver microsomes: possible role of hydroxyl radicals. Biochemical Pharmacology. 30: 825-831. PMID 6264923 DOI: 10.1016/S0006-2952(81)80002-0  0.477
1980 Cederbaum AI, Cohen G. Oxidative demethylation of t-butyl alcohol by rat liver microsomes Biochemical and Biophysical Research Communications. 97: 730-736. PMID 7470124 DOI: 10.1016/0006-291X(80)90325-3  0.458
1980 Cohen G, Cederbaum AI. Microsomal metabolism of hydroxyl radical scavenging agents: relationship to the microsomal oxidation of alcohols. Archives of Biochemistry and Biophysics. 199: 438-447. PMID 7362238 DOI: 10.1016/0003-9861(80)90300-8  0.508
1980 Cederbaum AI, Dicker E, Cohen G. Role of hydroxyl radicals in microsomal oxidation of alcohols. Advances in Experimental Medicine and Biology. 132: 1-10. PMID 6999867 DOI: 10.1007/978-1-4757-1419-7_1  0.51
1980 Cederbaum AI, Cohen G. Inhibition of the microsomal oxidation of ethanol and 1-butanol by the free-radical, spin-trapping agent 5,5-dimethyl-1-pyrroline-1-oxide Archives of Biochemistry and Biophysics. 204: 397-403. PMID 6778392 DOI: 10.1016/0003-9861(80)90049-1  0.506
1980 Cederbaum AI, Dicker E, Cohen G. Role of hydroxyl radicals in the iron-ethylenediaminetetraacetic acid mediated stimulation of microsomal oxidation of ethanol. Biochemistry. 19: 3698-3704. PMID 6773547 DOI: 10.1021/Bi00557A010  0.454
1980 Cederbaum AI, Miwa G, Cohen G, Lu AY. Production of hydroxyl radicals and their role in the oxidation of ethanol by a reconstituted microsomal system containing cytochrome P-450 purified from phenobarbital-treated rats. Biochemical and Biophysical Research Communications. 91: 747-54. PMID 526278 DOI: 10.1016/0006-291X(79)91943-0  0.511
1980 Cohen G, Cederbaum AI. The Production Of Hydroxyl Radicals By Rat Liver Microsomes Microsomes, Drug Oxidations and Chemical Carcinogenesis. 307-310. DOI: 10.1016/B978-0-12-187701-9.50057-7  0.411
1979 Cederbaum AI, Dicker E. The effect of pargyline on the metabolism of ethanol and acetaldehyde by isolated rat liver cells. Archives of Biochemistry and Biophysics. 193: 551-559. PMID 464611 DOI: 10.1016/0003-9861(79)90062-6  0.492
1979 Cohen G, Cederbaum AI. Chemical evidence for production of hydroxyl radicals during microsomal electron transfer Science. 204: 66-68. PMID 432627 DOI: 10.1126/Science.432627  0.373
1979 Cederbaum AI, Dicker E, Rubin E, Cohen G. Effect of thiourea on microsomal oxidation of alcohols and associated microsomal functions. Biochemistry. 18: 1187-1191. PMID 427108 DOI: 10.1021/Bi00574A011  0.492
1979 Cederbaum AI, Dicker E. The effect of acetaldehyde on gluconeogenesis from xylitol, sorbitol, and fructose by isolated rat liver cells. Archives of Biochemistry and Biophysics. 197: 415-423. PMID 228600 DOI: 10.1016/0003-9861(79)90263-7  0.456
1978 Cederbaum AI, Dicker E, Cohen G. Effect of hydroxyl radical scavengers on microsomal oxidation of alcohols and on associated microsomal reactions. Biochemistry. 17: 3058-3064. PMID 698185 DOI: 10.1021/Bi00608A018  0.41
1978 Cederbaum AI, Dicker E, Lieber CS, Rubin E. Ethanol oxidation by isolated hepatocytes from ethanol-treated and control rats; factors contributing to the metabolic adaptation after chronic ethanol consumption. Biochemical Pharmacology. 27: 7-15. PMID 563723 DOI: 10.1016/0006-2952(78)90250-2  0.466
1978 Cederbaum AI. The effect of calcium on the oxidation of acetaldehyde by rat liver mitochondria. Life Sciences. 22: 111-125. PMID 203810 DOI: 10.1016/0024-3205(78)90419-8  0.416
1977 Cederbaum AI, Dicker E, Rubin E, Cohen G. The effect of dimethylsulfoxide and other hydroxyl radical scavengers on the oxidation of ethanol by rat liver microsomes. Biochemical and Biophysical Research Communications. 78: 1254-1262. PMID 921777 DOI: 10.1016/0006-291X(77)91428-0  0.504
1977 Cederbaum AI, Dicker E, Rubin E. Transfer and reoxidation of reducing equivalents as the rate-limiting steps in the oxidation of ethanol by liver cells isolated from fed and fasted rats. Archives of Biochemistry and Biophysics. 183: 638-646. PMID 921281 DOI: 10.1016/0003-9861(77)90398-8  0.515
1977 Cederbaum AI, Rubin E. The oxidation of acetaldehyde by isolated mitochondria from various organs of the rat and hepatocellular carcinoma. Archives of Biochemistry and Biophysics. 179: 46-66. PMID 843090 DOI: 10.1016/0003-9861(77)90085-6  0.465
1977 Cederbaum AI, Dicker E, Lieber CS, Rubin E. Factors contributing to the adaptive increase in ethanol metabolism due to chronic consumption of ethanol. Alcoholism: Clinical and Experimental Research. 1: 27-31. PMID 337821 DOI: 10.1111/J.1530-0277.1977.Tb05762.X  0.46
1977 Cederbaum AI, Rubin E. Sensitivity to acetaldehyde of pyruvate oxidation by mitochondria from liver, kidney, brain and muscle Biochemical Pharmacology. 26: 1349-1353. DOI: 10.1016/0006-2952(77)90097-1  0.355
1976 Cederbaum AI, Rubin E. Protective effect of cysteine on the inhibition of mitochondrial functions by acetaldehyde. Biochemical Pharmacology. 25: 963-973. PMID 1267840 DOI: 10.1016/0006-2952(76)90323-3  0.459
1976 Cederbaum AI, Rubin E. Mechanism of the protective action of cysteine and penicillamine against acetaldehyde-induced mitochondrial injury. Biochemical Pharmacology. 25: 2179-2185. PMID 971330 DOI: 10.1016/0006-2952(76)90130-1  0.42
1976 Cederbaum AI, Lieber CS, Rubin E. Effect of chronic ethanol consumption and acetaldehyde on partial reactions of oxidative phosphorylation and CO2 production from citric acid cycle intermediates. Archives of Biochemistry and Biophysics. 176: 525-538. PMID 185964 DOI: 10.1016/0003-9861(76)90196-X  0.454
1976 Cederbaum AI, Madhavan TV, Rubin E. Effect of chronic clofibrate administration on mitochondrial fatty acid oxidation. Biochemical Pharmacology. 25: 1285-1292. PMID 132932 DOI: 10.1016/0006-2952(76)90091-5  0.438
1975 Cederbaum AI, Lieber CS, Rubin E. Effect of acetaldehyde on fatty acid oxidation and ketogenesis by hepatic mitochondria. Archives of Biochemistry and Biophysics. 169: 29-41. PMID 1164023 DOI: 10.1016/0003-9861(75)90313-6  0.441
1975 Cederbaum AI, Rubin E. Differential effects of acetate on palmitate and octanoate oxidation: segregation of acetyl CoA pools. Archives of Biochemistry and Biophysics. 166: 618-628. PMID 1119812 DOI: 10.1016/0003-9861(75)90428-2  0.424
1975 Cederbaum AI, Pietrusko R, Hempel J, Becker FF, Rubin E. Characterization of a nonhepatic alcohol dehydrogenase from rat hepatocellular carcinoma and stomach Archives of Biochemistry and Biophysics. 171: 348-360. PMID 172025 DOI: 10.1016/0003-9861(75)90042-9  0.413
1974 Cederbaum AI, Lieber CS, Beattie DS, Rubin E. Characterization of shuttle mechanisms for the transport of reducing equivalents into mitochondria. Archives of Biochemistry and Biophysics. 158: 763-81. PMID 4782532 DOI: 10.1016/0003-9861(73)90571-7  0.427
1974 Cederbaum AI, Rubin E. Effects of clofibrate on mitochondrial function. Biochemical Pharmacology. 23: 1985-1996. PMID 4370803 DOI: 10.1016/0006-2952(74)90257-3  0.375
1974 Cederbaum AI, Rubin E. Effects of pyrazole, 4-bromopyrazole and 4-methylpyrazole on mitochondrial function. Biochemical Pharmacology. 23: 203-213. PMID 4360345 DOI: 10.1016/0006-2952(74)90411-0  0.417
1974 Cederbaum AI, Lieber CS, Rubin E. Effects of chronic ethanol treatment on mitochondrial functions damage to coupling site I Archives of Biochemistry and Biophysics. 165: 560-569. PMID 4280268 DOI: 10.1016/0003-9861(74)90283-5  0.463
1974 Cederbaum AI, Lieber CS, Rubin E. The effect of acetaldehyde on mitochondrial function Archives of Biochemistry and Biophysics. 161: 26-39. DOI: 10.1016/0003-9861(74)90231-8  0.467
1973 Gang H, Cederbaum AI, Rubin E. Stereospecificity of ethanol oxidation. Biochemical and Biophysical Research Communications. 54: 264-269. PMID 4582378 DOI: 10.1016/0006-291X(73)90917-0  0.448
1973 Cederbaum AI, Lieber CS, Rubin E. Effect of acetaldehyde on activity of shuttles for the transport of reducing equivalents into the mitochondria. Febs Letters. 37: 89-92. PMID 4356722 DOI: 10.1016/0014-5793(73)80432-6  0.501
1973 Cederbaum AI, Lieber CS, Beattie DS, Rubin E. Effect of chronic ethanol ingestion on mitochondrial permeability and the transport of reducing equivalents. Biochemical and Biophysical Research Communications. 49: 649-55. PMID 4344683 DOI: 10.1016/0006-291X(72)90460-3  0.393
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