Fanxin Long - Publications

Affiliations: 
Biology & Biomedical Sciences (Developmental Biology) Washington University, Saint Louis, St. Louis, MO 
Area:
Human Development, Molecular Biology

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ji X, Seeley R, Li K, Song F, Liao X, Song C, Angelozzi M, Valeri A, Marmo T, Lee WC, Shi Y, Long F. Genetic activation of glycolysis in osteoblasts preserves bone mass in type I diabetes. Cell Chemical Biology. PMID 37562406 DOI: 10.1016/j.chembiol.2023.07.003  0.377
2023 Song F, Lee WD, Marmo T, Ji X, Song C, Liao X, Seeley R, Yao L, Liu H, Long F. Osteoblast-intrinsic defect in glucose metabolism impairs bone formation in type II diabetic male mice. Elife. 12. PMID 37144869 DOI: 10.7554/eLife.85714  0.336
2023 Song F, Lee WD, Marmo T, Ji X, Song C, Liao X, Seeley R, Yao L, Liu H, Long F. Osteoblast-intrinsic defect in glucose metabolism impairs bone formation in type II diabetic mice. Biorxiv : the Preprint Server For Biology. PMID 36711657 DOI: 10.1101/2023.01.16.524248  0.332
2022 Long F. Glucose metabolism in skeletal cells. Bone Reports. 17: 101640. PMID 36438715 DOI: 10.1016/j.bonr.2022.101640  0.456
2022 Xue L, Gong N, Shepherd SJ, Xiong X, Liao X, Han X, Zhao G, Song C, Huang X, Zhang H, Padilla MS, Qin J, Shi Y, Alameh MG, Pochan DJ, ... ... Long F, et al. Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment. Journal of the American Chemical Society. PMID 35616998 DOI: 10.1021/jacs.2c02706  0.395
2021 Shi Y, Liao X, Long JY, Yao L, Chen J, Yin B, Lou F, He G, Ye L, Qin L, Long F. Gli1 progenitors mediate bone anabolic function of teriparatide via Hh and Igf signaling. Cell Reports. 36: 109542. PMID 34407400 DOI: 10.1016/j.celrep.2021.109542  0.417
2021 Chen H, Song F, Long F. WNT7B overexpression rescues bone loss caused by glucocorticoids in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21683. PMID 34118078 DOI: 10.1096/fj.202100151RR  0.455
2021 Song D, He G, Shi Y, Ni J, Long F. Functional interaction between Wnt and Bmp signaling in periosteal bone growth. Scientific Reports. 11: 10782. PMID 34031510 DOI: 10.1038/s41598-021-90324-1  0.547
2020 Song D, He G, Song F, Wang Z, Liu X, Liao L, Ni J, Silva MJ, Long F. Inducible expression of Wnt7b promotes bone formation in aged mice and enhances fracture healing. Bone Research. 8: 4. PMID 33526766 DOI: 10.1038/s41413-019-0081-8  0.401
2020 Shen L, Sharma D, Yu Y, Long F, Karner C. Biphasic regulation of glutamine consumption by WNT during osteoblast differentiation. Journal of Cell Science. PMID 33262314 DOI: 10.1242/jcs.251645  0.673
2020 Li B, Lee WC, Song C, Ye L, Abel ED, Long F. Both aerobic glycolysis and mitochondrial respiration are required for osteoclast differentiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32627870 DOI: 10.1096/Fj.202000771R  0.37
2020 Hu G, Yu Y, Tang YJ, Wu C, Long F, Karner CM. The amino acid sensor Eif2ak4/GCN2 is required for proliferation of osteoblast progenitors in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 32453500 DOI: 10.1002/jbmr.4091  0.423
2020 Shi Y, Saben JL, He G, Moley KH, Long F. Diet-Induced Metabolic Dysregulation in Female Mice Causes Osteopenia in Adult Offspring. Journal of the Endocrine Society. 4: bvaa028. PMID 32309754 DOI: 10.1210/Jendso/Bvaa028  0.389
2020 Zhong L, Yao L, Tower RJ, Wei Y, Miao Z, Park J, Shrestha R, Wang L, Yu W, Holdreith N, Huang X, Zhang Y, Tong W, Gong Y, Ahn J, ... ... Long F, et al. Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment. Elife. 9. PMID 32286228 DOI: 10.7554/Elife.54695  0.437
2020 Song D, He G, Song F, Wang Z, Liu X, Liao L, Ni J, Silva MJ, Long F. Inducible expression of Wnt7b promotes bone formation in aged mice and enhances fracture healing. Bone Research. 8: 4. PMID 32047703 DOI: 10.1038/S41413-019-0081-8  0.496
2019 Chen H, Ji X, Lee WC, Shi Y, Li B, Abel ED, Jiang D, Huang W, Long F. Increased glycolysis mediates Wnt7b-induced bone formation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900201RR. PMID 30913395 DOI: 10.1096/Fj.201900201Rr  0.477
2018 Lee SY, Abel ED, Long F. Glucose metabolism induced by Bmp signaling is essential for murine skeletal development. Nature Communications. 9: 4831. PMID 30446646 DOI: 10.1038/S41467-018-07316-5  0.465
2018 Lee SY, Long F. Notch signaling suppresses glucose metabolism in mesenchymal progenitors to restrict osteoblast differentiation. The Journal of Clinical Investigation. PMID 30284985 DOI: 10.1172/Jci96221  0.598
2018 Long F. Energy Metabolism and Bone. Bone. 115: 1. PMID 30146067 DOI: 10.1016/J.Bone.2018.08.002  0.403
2018 Xu C, Zou C, Hussain M, Shi W, Shao Y, Jiang Z, Wu X, Lu M, Wu J, Xie Q, Ke Y, Long F, Tang L, Wu X. High expression of Sonic hedgehog in allergic airway epithelia contributes to goblet cell metaplasia. Mucosal Immunology. PMID 29867080 DOI: 10.1038/S41385-018-0033-4  0.367
2018 Chen J, Long F. mTOR signaling in skeletal development and disease. Bone Research. 6: 1. PMID 29423330 DOI: 10.1038/S41413-017-0004-5  0.539
2017 Shi Y, He G, Lee WC, McKenzie JA, Silva MJ, Long F. Gli1 identifies osteogenic progenitors for bone formation and fracture repair. Nature Communications. 8: 2043. PMID 29230039 DOI: 10.1038/S41467-017-02171-2  0.529
2017 Karner CM, Long F. Glucose metabolism in bone. Bone. PMID 28843700 DOI: 10.1016/J.Bone.2017.08.008  0.487
2017 He G, Shi Y, Lim J, Bellido T, Ni J, Long F. Differential involvement of Wnt signaling in Bmp regulation of cancellous versus periosteal bone growth. Bone Research. 5: 17016. PMID 28607813 DOI: 10.1038/Boneres.2017.16  0.624
2017 Lee WC, Guntur AR, Long F, Rosen CJ. Energy Metabolism of the Osteoblast: Implications for Osteoporosis. Endocrine Reviews. PMID 28472361 DOI: 10.1210/Er.2017-00064  0.344
2017 Lim J, Burclaff J, He G, Mills JC, Long F. Unintended targeting of Dmp1-Cre reveals a critical role for Bmpr1a signaling in the gastrointestinal mesenchyme of adult mice. Bone Research. 5: 16049. PMID 28163952 DOI: 10.1038/Boneres.2016.49  0.537
2016 Karner CM, Lee SY, Long F. Bmp induces osteoblast differentiation through both Smad4 and mTORC1 signaling. Molecular and Cellular Biology. PMID 27920253 DOI: 10.1128/Mcb.00253-16  0.581
2016 Karner CM, Long F. Wnt signaling and cellular metabolism in osteoblasts. Cellular and Molecular Life Sciences : Cmls. PMID 27888287 DOI: 10.1007/S00018-016-2425-5  0.603
2016 Jiang M, Fu X, Yang H, Long F, Chen J. mTORC1 Signaling Promotes Limb Bud Cell Growth and Chondrogenesis. Journal of Cellular Biochemistry. PMID 27606668 DOI: 10.1002/jcb.25728  0.401
2016 Karner CM, Esen E, Chen J, Hsu FF, Turk J, Long F. Wnt Signaling Reduces Nuclear Acetyl-coA Levels to Suppress Gene Expression during Osteoblast Differentiation. The Journal of Biological Chemistry. PMID 27129247 DOI: 10.1074/Jbc.M115.708578  0.479
2016 Karuppaiah K, Yu K, Lim J, Chen J, Smith C, Long F, Ornitz DM. FGF signaling in the osteoprogenitor lineage non-autonomously regulates postnatal chondrocyte proliferation and skeletal growth. Development (Cambridge, England). PMID 27052727 DOI: 10.1242/Dev.131722  0.584
2016 Sun W, Shi Y, Lee WC, Lee SY, Long F. Rictor is required for optimal bone accrual in response to anti-sclerostin therapy in the mouse. Bone. PMID 26780446 DOI: 10.1016/J.Bone.2016.01.013  0.566
2016 Wang J, Wang C, Xu C, Wu X, Hong D, Shi W, Gong Y, Chen H, Long F, Wu X. Signaling Cascades Governing Cdc42-Mediated Chondrogenic Differentiation and Mensenchymal Condensation. Genetics. PMID 26739452 DOI: 10.1534/Genetics.115.180109  0.591
2015 Luo X, Fu Y, Loza AJ, Murali B, Leahy KM, Ruhland MK, Gang M, Su X, Zamani A, Shi Y, Lavine KJ, Ornitz DM, Weilbaecher KN, Long F, Novack DV, et al. Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development. Cell Reports. PMID 26725121 DOI: 10.1016/J.Celrep.2015.12.016  0.481
2015 Lim J, Shi Y, Karner CM, Lee SY, Lee WC, He G, Long F. Dual function of Bmpr1a signaling in restricting preosteoblast proliferation and stimulating osteoblast activity in the mouse. Development (Cambridge, England). PMID 26657771 DOI: 10.1242/Dev.126227  0.615
2015 Esen E, Lee SY, Wice BM, Long F. PTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 2137. PMID 26477607 DOI: 10.1002/Jbmr.2714  0.524
2015 Kazmers NH, McKenzie JA, Shen TS, Long F, Silva MJ. Hedgehog signaling mediates woven bone formation and vascularization during stress fracture healing. Bone. 81: 524-532. PMID 26348666 DOI: 10.1016/J.Bone.2015.09.002  0.399
2015 Chen J, Long F. mTORC1 Signaling Promotes Osteoblast Differentiation from Preosteoblasts. Plos One. 10: e0130627. PMID 26090674 DOI: 10.1371/Journal.Pone.0130627  0.562
2015 Esen E, Lee SY, Wice BM, Long F. PTH Promotes Bone Anabolism by Stimulating Aerobic Glycolysis via IGF Signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 1959-68. PMID 25990470 DOI: 10.1002/Jbmr.2556  0.515
2015 Karner CM, Long F, Solnica-Krezel L, Monk KR, Gray RS. Gpr126/Adgrg6 deletion in cartilage models idiopathic scoliosis and pectus excavatum in mice. Human Molecular Genetics. PMID 25954032 DOI: 10.1093/Hmg/Ddv170  0.328
2015 Shi Y, Chen J, Karner CM, Long F. Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation. Proceedings of the National Academy of Sciences of the United States of America. 112: 4678-83. PMID 25825734 DOI: 10.1073/Pnas.1502301112  0.539
2015 Lim J, Tu X, Choi K, Akiyama H, Mishina Y, Long F. BMP-Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse. Developmental Biology. 400: 132-8. PMID 25641697 DOI: 10.1016/J.Ydbio.2015.01.022  0.603
2015 Tang C, Pan Y, Luo H, Xiong W, Zhu H, Ruan H, Wang J, Zou C, Tang L, Iguchi T, Long F, Wu X. Hedgehog signaling stimulates the conversion of cholesterol to steroids. Cellular Signalling. 27: 487-97. PMID 25582983 DOI: 10.1016/J.Cellsig.2015.01.004  0.404
2015 Karner CM, Esen E, Okunade AL, Patterson BW, Long F. Increased glutamine catabolism mediates bone anabolism in response to WNT signaling. The Journal of Clinical Investigation. 125: 551-62. PMID 25562323 DOI: 10.1172/Jci78470  0.554
2015 Schwartz AG, Long F, Thomopoulos S. Enthesis fibrocartilage cells originate from a population of Hedgehog-responsive cells modulated by the loading environment. Development (Cambridge, England). 142: 196-206. PMID 25516975 DOI: 10.1242/Dev.112714  0.456
2015 Chen J, Holguin N, Shi Y, Silva MJ, Long F. mTORC2 signaling promotes skeletal growth and bone formation in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 369-78. PMID 25196701 DOI: 10.1002/Jbmr.2348  0.597
2014 Joeng KS, Long F. Wnt7b can replace Ihh to induce hypertrophic cartilage vascularization but not osteoblast differentiation during endochondral bone development. Bone Research. 2: 14004. PMID 26273517 DOI: 10.1038/Boneres.2014.4  0.801
2014 Esen E, Long F. Aerobic glycolysis in osteoblasts Current Osteoporosis Reports. 12: 433-438. PMID 25200872 DOI: 10.1007/S11914-014-0235-Y  0.477
2014 Gu S, Wu W, Liu C, Yang L, Sun C, Ye W, Li X, Chen J, Long F, Chen Y. BMPRIA mediated signaling is essential for temporomandibular joint development in mice. Plos One. 9: e101000. PMID 25093411 DOI: 10.1371/Journal.Pone.0101000  0.504
2014 Chen J, Long F. mTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis. Development (Cambridge, England). 141: 2848-54. PMID 24948603 DOI: 10.1242/Dev.108811  0.481
2014 Regan JN, Lim J, Shi Y, Joeng KS, Arbeit JM, Shohet RV, Long F. Up-regulation of glycolytic metabolism is required for HIF1α-driven bone formation. Proceedings of the National Academy of Sciences of the United States of America. 111: 8673-8. PMID 24912186 DOI: 10.1073/Pnas.1324290111  0.781
2014 Swarnkar G, Zhang K, Mbalaviele G, Long F, Abu-Amer Y. Constitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development. Plos One. 9: e91421. PMID 24618907 DOI: 10.1371/Journal.Pone.0091421  0.44
2014 Chen J, Tu X, Esen E, Joeng KS, Lin C, Arbeit JM, Rüegg MA, Hall MN, Ma L, Long F. WNT7B promotes bone formation in part through mTORC1. Plos Genetics. 10: e1004145. PMID 24497849 DOI: 10.1371/Journal.Pgen.1004145  0.811
2014 Joeng KS, Regan J, Long F. Radioactive in situ hybridization to detect gene expression in skeletal tissue sections. Methods in Molecular Biology (Clifton, N.J.). 1130: 217-32. PMID 24482176 DOI: 10.1007/978-1-62703-989-5_16  0.667
2014 Chen J, Shi Y, Regan J, Karuppaiah K, Ornitz DM, Long F. Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice. Plos One. 9: e85161. PMID 24454809 DOI: 10.1371/Journal.Pone.0085161  0.442
2013 Esen E, Chen J, Karner CM, Okunade AL, Patterson BW, Long F. WNT-LRP5 signaling induces Warburg effect through mTORC2 activation during osteoblast differentiation. Cell Metabolism. 17: 745-55. PMID 23623748 DOI: 10.1016/J.Cmet.2013.03.017  0.596
2013 Regan J, Long F. Notch signaling and bone remodeling. Current Osteoporosis Reports. 11: 126-9. PMID 23519781 DOI: 10.1007/S11914-013-0145-4  0.593
2013 Cary RL, Waddell S, Racioppi L, Long F, Novack DV, Voor MJ, Sankar U. Inhibition of Ca²⁺/calmodulin-dependent protein kinase kinase 2 stimulates osteoblast formation and inhibits osteoclast differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1599-610. PMID 23408651 DOI: 10.1002/Jbmr.1890  0.547
2013 Zheng D, Decker KF, Zhou T, Chen J, Qi Z, Jacobs K, Weilbaecher KN, Corey E, Long F, Jia L. Role of WNT7B-induced noncanonical pathway in advanced prostate cancer. Molecular Cancer Research : McR. 11: 482-93. PMID 23386686 DOI: 10.1158/1541-7786.Mcr-12-0520  0.334
2013 Joeng KS, Long F. Constitutive activation of Gli2 impairs bone formation in postnatal growing mice. Plos One. 8: e55134. PMID 23383082 DOI: 10.1371/Journal.Pone.0055134  0.812
2013 Long F, Ornitz DM. Development of the endochondral skeleton. Cold Spring Harbor Perspectives in Biology. 5: a008334. PMID 23284041 DOI: 10.1101/Cshperspect.A008334  0.58
2013 Chen J, Long F. β-catenin promotes bone formation and suppresses bone resorption in postnatal growing mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1160-9. PMID 23188722 DOI: 10.1002/Jbmr.1834  0.549
2012 Choi SW, Jeong DU, Kim JA, Lee B, Joeng KS, Long F, Kim DW. Indian Hedgehog signalling triggers Nkx3.2 protein degradation during chondrocyte maturation Biochemical Journal. 443: 789-798. PMID 22507129 DOI: 10.1042/Bj20112062  0.776
2012 Tu X, Chen J, Lim J, Karner CM, Lee SY, Heisig J, Wiese C, Surendran K, Kopan R, Gessler M, Long F. Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1. Plos Genetics. 8: e1002577. PMID 22457635 DOI: 10.1371/Journal.Pgen.1002577  0.632
2012 Long F. Building strong bones: molecular regulation of the osteoblast lineage. Nature Reviews. Molecular Cell Biology. 13: 27-38. PMID 22189423 DOI: 10.1038/Nrm3254  0.594
2012 Heller E, Hurchla MA, Xiang J, Su X, Chen S, Schneider J, Joeng KS, Vidal M, Goldberg L, Deng H, Hornick MC, Prior JL, Piwnica-Worms D, Long F, Cagan R, et al. Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment. Cancer Research. 72: 897-907. PMID 22186138 DOI: 10.1158/0008-5472.Can-11-2681  0.733
2012 Tu X, Joeng KS, Long F. Indian hedgehog requires additional effectors besides Runx2 to induce osteoblast differentiation. Developmental Biology. 362: 76-82. PMID 22155527 DOI: 10.1016/J.Ydbio.2011.11.013  0.778
2011 Joeng KS, Schumacher CA, Zylstra-Diegel CR, Long F, Williams BO. Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo. Developmental Biology. 359: 222-9. PMID 21924256 DOI: 10.1016/J.Ydbio.2011.08.020  0.752
2010 Wan C, Shao J, Gilbert SR, Riddle RC, Long F, Johnson RS, Schipani E, Clemens TL. Role of HIF-1alpha in skeletal development. Annals of the New York Academy of Sciences. 1192: 322-6. PMID 20392254 DOI: 10.1111/J.1749-6632.2009.05238.X  0.523
2010 Long F. Noncanonical Wnt Signaling in Bone Endocrinology and Metabolism. 25: 85. DOI: 10.3803/ENM.2010.25.2.85  0.5
2009 Lin C, Yin Y, Veith GM, Fisher AV, Long F, Ma L. Temporal and spatial dissection of Shh signaling in genital tubercle development. Development (Cambridge, England). 136: 3959-67. PMID 19906863 DOI: 10.1242/Dev.039768  0.483
2009 Joeng KS, Long F. The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization. Development (Cambridge, England). 136: 4177-85. PMID 19906844 DOI: 10.1242/Dev.041624  0.768
2009 Ma YD, Park C, Zhao H, Oduro KA, Tu X, Long F, Allen PM, Teitelbaum SL, Choi K. Defects in osteoblast function but no changes in long-term repopulating potential of hematopoietic stem cells in a mouse chronic inflammatory arthritis model. Blood. 114: 4402-10. PMID 19759358 DOI: 10.1182/Blood-2008-12-196311  0.433
2009 Metcalf JA, Zhang Y, Hilton MJ, Long F, Ponder KP. Mechanism of shortened bones in mucopolysaccharidosis VII. Molecular Genetics and Metabolism. 97: 202-11. PMID 19375967 DOI: 10.1016/J.Ymgme.2009.03.005  0.722
2009 Christopher MJ, Liu F, Hilton MJ, Long F, Link DC. Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization. Blood. 114: 1331-9. PMID 19141863 DOI: 10.1182/Blood-2008-10-184754  0.743
2009 Long F. Bone Appétit! Cell. 139: 1044-1045. DOI: 10.1016/j.cell.2009.11.032  0.393
2009 Long F. On non-canonical wnt signaling cascades: Insights from osteogenic cells Bone. 44: S204. DOI: 10.1016/J.Bone.2009.03.021  0.452
2008 Long F. When the gut talks to bone. Cell. 135: 795-6. PMID 19041744 DOI: 10.1016/J.Cell.2008.11.007  0.52
2008 Lavine KJ, Long F, Choi K, Smith C, Ornitz DM. Hedgehog signaling to distinct cell types differentially regulates coronary artery and vein development. Development (Cambridge, England). 135: 3161-71. PMID 18725519 DOI: 10.1242/Dev.019919  0.367
2008 Long F. Targeting intercellular signals for bone regeneration from bone marrow mesenchymal progenitors. Cell Cycle (Georgetown, Tex.). 7: 2106-11. PMID 18635951 DOI: 10.4161/cc.7.14.6257  0.47
2008 Lin C, Yin Y, Long F, Ma L. Tissue-specific requirements of beta-catenin in external genitalia development. Development (Cambridge, England). 135: 2815-25. PMID 18635608 DOI: 10.1242/Dev.020586  0.393
2008 Yin Y, White AC, Huh SH, Hilton MJ, Kanazawa H, Long F, Ornitz DM. An FGF-WNT gene regulatory network controls lung mesenchyme development. Developmental Biology. 319: 426-36. PMID 18533146 DOI: 10.1016/J.Ydbio.2008.04.009  0.655
2008 Wu X, Tu X, Joeng KS, Hilton MJ, Williams DA, Long F. Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling. Cell. 133: 340-53. PMID 18423204 DOI: 10.1016/J.Cell.2008.01.052  0.758
2008 Hilton MJ, Tu X, Wu X, Bai S, Zhao H, Kobayashi T, Kronenberg HM, Teitelbaum SL, Ross FP, Kopan R, Long F. Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation. Nature Medicine. 14: 306-14. PMID 18297083 DOI: 10.1038/Nm1716  0.781
2008 Bai S, Kopan R, Zou W, Hilton MJ, Ong CT, Long F, Ross FP, Teitelbaum SL. NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. The Journal of Biological Chemistry. 283: 6509-18. PMID 18156632 DOI: 10.1074/Jbc.M707000200  0.772
2007 Hilton MJ, Tu X, Long F. Tamoxifen-inducible gene deletion reveals a distinct cell type associated with trabecular bone, and direct regulation of PTHrP expression and chondrocyte morphology by Ihh in growth region cartilage. Developmental Biology. 308: 93-105. PMID 17560974 DOI: 10.1016/J.Ydbio.2007.05.011  0.755
2007 Yu L, Liu H, Yan M, Yang J, Long F, Muneoka K, Chen Y. Shox2 is required for chondrocyte proliferation and maturation in proximal limb skeleton. Developmental Biology. 306: 549-59. PMID 17481601 DOI: 10.1016/J.Ydbio.2007.03.518  0.465
2007 Zou W, Kitaura H, Reeve J, Long F, Tybulewicz VL, Shattil SJ, Ginsberg MH, Ross FP, Teitelbaum SL. Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption. The Journal of Cell Biology. 176: 877-88. PMID 17353363 DOI: 10.1083/Jcb.200611083  0.496
2007 Tu X, Joeng KS, Nakayama KI, Nakayama K, Rajagopal J, Carroll TJ, McMahon AP, Long F. Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation. Developmental Cell. 12: 113-27. PMID 17199045 DOI: 10.1016/J.Devcel.2006.11.003  0.813
2007 Shibukawa Y, Young B, Wu C, Yamada S, Long F, Pacifici M, Koyama E. Temporomandibular joint formation and condyle growth require Indian hedgehog signaling. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 426-34. PMID 17191253 DOI: 10.1002/Dvdy.21036  0.357
2007 Zou W, Kitaura H, Reeve J, Long F, Tybulewicz VL, Shattil SJ, Ginsberg MH, Ross FP, Teitelbaum SL. Syk, c-Src, the αvβ3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption The Journal of Experimental Medicine. 204: i8-i8. DOI: 10.1084/JEM2043OIA8  0.404
2006 Long F, Joeng KS, Xuan S, Efstratiadis A, McMahon AP. Independent regulation of skeletal growth by Ihh and IGF signaling. Developmental Biology. 298: 327-33. PMID 16905129 DOI: 10.1016/J.Ydbio.2006.06.042  0.712
2006 Lavine KJ, White AC, Park C, Smith CS, Choi K, Long F, Hui CC, Ornitz DM. Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development. Genes & Development. 20: 1651-66. PMID 16778080 DOI: 10.1101/Gad.1411406  0.388
2005 Razzaque MS, Soegiarto DW, Chang D, Long F, Lanske B. Conditional deletion of Indian hedgehog from collagen type 2alpha1-expressing cells results in abnormal endochondral bone formation. The Journal of Pathology. 207: 453-61. PMID 16278811 DOI: 10.1002/path.1870  0.493
2005 Hilton MJ, Tu X, Cook J, Hu H, Long F. Ihh controls cartilage development by antagonizing Gli3, but requires additional effectors to regulate osteoblast and vascular development. Development (Cambridge, England). 132: 4339-51. PMID 16141219 DOI: 10.1242/Dev.02025  0.726
2005 Glass DA, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Developmental Cell. 8: 751-64. PMID 15866165 DOI: 10.1016/J.Devcel.2005.02.017  0.601
2005 Hu H, Hilton MJ, Tu X, Yu K, Ornitz DM, Long F. Sequential roles of Hedgehog and Wnt signaling in osteoblast development. Development (Cambridge, England). 132: 49-60. PMID 15576404 DOI: 10.1242/Dev.01564  0.745
2004 Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP. Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development (Cambridge, England). 131: 1309-18. PMID 14973297 DOI: 10.1242/Dev.01006  0.619
2001 Di Nino DL, Long F, Linsenmayer TF. Regulation of endochondral cartilage growth in the developing avian limb: cooperative involvement of perichondrium and periosteum. Developmental Biology. 240: 433-42. PMID 11784074 DOI: 10.1006/Dbio.2001.0471  0.388
2001 Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature. 413: 179-83. PMID 11557984 DOI: 10.1038/35093131  0.373
2001 Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M. Erratum: correction: CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 Nature. 413: 652-652. DOI: 10.1038/35098123  0.303
1998 Linsenmayer TF, Long F, Nurminskaya M, Chen Q, Schmid TM. Type X collagen and other up-regulated components of the avian hypertrophic cartilage program. Progress in Nucleic Acid Research and Molecular Biology. 60: 79-109. PMID 9594572 DOI: 10.1016/S0079-6603(08)60890-9  0.348
1998 Long F, Sonenshein GE, Linsenmayer TF. Multiple transcriptional elements in the avian type X collagen gene. Identification of Sp1 family proteins as regulators for high level expression in hypertrophic chondrocytes Journal of Biological Chemistry. 273: 6542-6549. PMID 9497390 DOI: 10.1074/Jbc.273.11.6542  0.404
1996 Long F, Linsenmayer TF. In vivo footprinting implicates negative regulators in the expression of the type X collagen gene in chickens. Annals of the New York Academy of Sciences. 785: 292-4. PMID 8702158 DOI: 10.1111/J.1749-6632.1996.Tb56287.X  0.319
1996 Long F, Linsenmayer TF. Tissue-specific regulation of the type X collagen gene. Analyses by in vivo footprinting and transfection with a proximal promoter region. The Journal of Biological Chemistry. 270: 31310-4. PMID 8537401 DOI: 10.1074/Jbc.270.52.31310  0.346
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