| Year |
Citation |
Score |
| 2020 |
Singh P, Wang X, Hageman L, Chen Y, Magdy T, Landier W, Ginsberg JP, Neglia JP, Sklar CA, Castellino SM, Dreyer ZE, Hudson MM, Robison LL, Blanco JG, Relling MV, et al. Association of GSTM1 null variant with anthracycline-related cardiomyopathy after childhood cancer-A Children's Oncology Group ALTE03N1 report. Cancer. PMID 32413235 DOI: 10.1002/Cncr.32948 |
0.32 |
|
| 2019 |
Lombraña AQ, Blanco JG. Comparative analysis of the DYRK1A-SRSF6-TNNT2 pathway in myocardial tissue from individuals with and without Down syndrome. Experimental and Molecular Pathology. 104268. PMID 31201803 DOI: 10.1016/J.Yexmp.2019.104268 |
0.317 |
|
| 2019 |
Quiñones-Lombraña A, Intini A, Blanco JG. Insights into the transcriptional regulation of the anthracycline reductase AKR7A2 in human cardiomyocytes. Toxicology Letters. 307: 11-16. PMID 30817976 DOI: 10.1016/J.Toxlet.2019.02.015 |
0.337 |
|
| 2019 |
Singh P, Wang X, Hageman L, Chen Y, Magdy T, Landier W, Ginsberg JP, Neglia JP, Sklar CA, Castellino SM, Dreyer ZE, Hudson MM, Robison LL, Blanco JG, Relling MV, et al. A novel association between GSTM1 null variant and anthracycline-induced cardiac dysfunction (ACD) in childhood cancer survivors (CCS): A COG ALTE03N1 report. Journal of Clinical Oncology. 37: 10030-10030. DOI: 10.1200/Jco.2019.37.15_Suppl.10030 |
0.382 |
|
| 2019 |
Wang X, Chen Y, Hageman L, Singh P, Landier W, Blanco JG, Hawkins DS, Ritchey AK, Ginsberg JP, Winick NJ, Sapkota Y, Yasui Y, Morton LM, Armstrong GT, Oeffinger KC, et al. Risk prediction of anthracycline-related cardiomyopathy (AC) in childhood cancer survivors (CCS): A COG-ALTE03N1 and CCSS report. Journal of Clinical Oncology. 37: 10015-10015. DOI: 10.1200/Jco.2019.37.15_Suppl.10015 |
0.358 |
|
| 2019 |
Lang J, Quinones A, Blair RH, Early A, Levine E, Opyrchal M, Blanco J, O'Connor T. Abstract P1-12-08: Association of CBR3 polymorphisms with an early change in cardiac function as assessed by left ventricular global longitudinal strain in breast cancer patients treated with doxorubicin Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-P1-12-08 |
0.316 |
|
| 2018 |
Lombraña AQ, Li N, Del Solar V, Ekin Atilla-Gokcumen G, Blanco JG. CBR1 rs9024 genotype status impacts the bioactivation of loxoprofen in human liver. Biopharmaceutics & Drug Disposition. PMID 29851133 DOI: 10.1002/Bdd.2135 |
0.383 |
|
| 2017 |
Quiñones-Lombraña A, Blair RH, Blanco JG. Investigation of the role of DNA methylation in the expression of ERBB2 in human myocardium. Gene. PMID 28735727 DOI: 10.1016/J.Gene.2017.07.058 |
0.338 |
|
| 2016 |
Quiñones-Lombraña A, Cheng Q, Ferguson DC, Blanco JG. Transcriptional regulation of the canine carbonyl reductase 1 gene (cbr1) by the specificity protein 1 (Sp1). Gene. PMID 27506315 DOI: 10.1016/J.Gene.2016.08.005 |
0.327 |
|
| 2016 |
Hoefer CC, Blair RH, Blanco JG. Development of a CART Model to Predict the Synthesis of Cardiotoxic Daunorubicinol in Heart Tissue Samples From Donors With and Without Down Syndrome. Journal of Pharmaceutical Sciences. 105: 2005-8. PMID 27112290 DOI: 10.1016/J.Xphs.2016.03.013 |
0.354 |
|
| 2016 |
Hoefer CC, Quiñones-Lombraña A, Blair RH, Blanco JG. Role of DNA Methylation on the Expression of the Anthracycline Metabolizing Enzyme AKR7A2 in Human Heart. Cardiovascular Toxicology. 16: 182-92. PMID 25962911 DOI: 10.1007/S12012-015-9327-X |
0.336 |
|
| 2016 |
Hefti E, Quiñones-Lombraña A, Redzematovic A, Hui J, Blanco JG. Analysis of mtDNA, miR-155 and BACH1 expression in hearts from donors with and without Down syndrome. Mitochondrial Dna. Part a. Dna Mapping, Sequencing, and Analysis. 27: 896-903. PMID 24938108 DOI: 10.3109/19401736.2014.926477 |
0.333 |
|
| 2015 |
Ferguson DC, Cheng Q, Blanco JG. Characterization of the Canine Anthracycline-Metabolizing Enzyme Carbonyl Reductase 1 (cbr1) and the Functional Isoform cbr1 V218. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 922-7. PMID 25918240 DOI: 10.1124/Dmd.115.064295 |
0.314 |
|
| 2015 |
Quiñones-Lombraña A, Blanco JG. Chromosome 21-derived hsa-miR-155-5p regulates mitochondrial biogenesis by targeting Mitochondrial Transcription Factor A (TFAM). Biochimica Et Biophysica Acta. 1852: 1420-7. PMID 25869329 DOI: 10.1016/J.Bbadis.2015.04.004 |
0.305 |
|
| 2014 |
Quiñones-Lombraña A, Ferguson D, Hageman Blair R, Kalabus JL, Redzematovic A, Blanco JG. Interindividual variability in the cardiac expression of anthracycline reductases in donors with and without Down syndrome. Pharmaceutical Research. 31: 1644-55. PMID 24562808 DOI: 10.1007/S11095-013-1267-1 |
0.725 |
|
| 2013 |
Gaudy A, Fetterly GJ, Adjei AA, O'Connor TL, Quinones A, Blanco JG, Ferguson D, Meholick PD, Kalabus J. Investigation of the pharmacogenetic influences of carbonyl reductase on doxorubicin and doxorubicinol in breast cancer patients. Journal of Clinical Oncology. 31: 2594-2594. DOI: 10.1200/Jco.2013.31.15_Suppl.2594 |
0.723 |
|
| 2012 |
Kalabus JL, Cheng Q, Blanco JG. MicroRNAs differentially regulate carbonyl reductase 1 (CBR1) gene expression dependent on the allele status of the common polymorphic variant rs9024. Plos One. 7: e48622. PMID 23133646 DOI: 10.1371/Journal.Pone.0048622 |
0.718 |
|
| 2012 |
Cheng Q, Sanborn C, Ferguson D, Blanco JG. DNA sequence variants in the carbonyl reductase 1 (cbr1) gene in seven breeds of Canis lupus familiaris. Genetics and Molecular Research : Gmr. 11: 1109-16. PMID 22614280 DOI: 10.4238/2012.April.27.10 |
0.317 |
|
| 2012 |
Kalabus JL, Cheng Q, Jamil RG, Schuetz EG, Blanco JG. Induction of carbonyl reductase 1 (CBR1) expression in human lung tissues and lung cancer cells by the cigarette smoke constituent benzo[a]pyrene. Toxicology Letters. 211: 266-73. PMID 22531821 DOI: 10.1016/J.Toxlet.2012.04.006 |
0.715 |
|
| 2012 |
Blanco JG, Sun CL, Landier W, Chen L, Esparza-Duran D, Leisenring W, Mays A, Friedman DL, Ginsberg JP, Hudson MM, Neglia JP, Oeffinger KC, Ritchey AK, Villaluna D, Relling MV, et al. Anthracycline-related cardiomyopathy after childhood cancer: role of polymorphisms in carbonyl reductase genes--a report from the Children's Oncology Group. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 1415-21. PMID 22124095 DOI: 10.1200/Jco.2011.34.8987 |
0.382 |
|
| 2012 |
Cheng Q, Kalabus JL, Zhang J, Blanco JG. A conserved antioxidant response element (ARE) in the promoter of human carbonyl reductase 3 (CBR3) mediates induction by the master redox switch Nrf2. Biochemical Pharmacology. 83: 139-48. PMID 22001310 DOI: 10.1016/J.Bcp.2011.09.027 |
0.712 |
|
| 2011 |
Fetterly GJ, Thudium KE, Kalabus J, Murphy M, Zagst PD, Prey J, Kittleman E, Adjei AA, O'Connor TL, Blanco JG. Understanding the role of carbonyl reductase polymorphisms on doxorubicin-induced cardiotoxicity with population pharmacokinetics (PK). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 2606. PMID 28022442 DOI: 10.1200/Jco.2011.29.15_Suppl.2606 |
0.738 |
|
| 2010 |
Kalabus JL, Sanborn CC, Jamil RG, Cheng Q, Blanco JG. Expression of the anthracycline-metabolizing enzyme carbonyl reductase 1 in hearts from donors with Down syndrome. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 2096-9. PMID 20729274 DOI: 10.1124/Dmd.110.035550 |
0.737 |
|
| 2010 |
Blanco JG, Sun C, Landier W, Chen L, Oeffinger KC, Hudson MM, Neglia JP, Ritchey AK, Relling MV, Bhatia S. Anthracycline-related cardiomyopathy in childhood cancer survivors and association with polymorphisms in the carbonyl reductase genes: A Children's Oncology Group study. Journal of Clinical Oncology. 28: 9512-9512. DOI: 10.1200/Jco.2010.28.15_Suppl.9512 |
0.332 |
|
| 2009 |
Choi JY, Barlow WE, Albain KS, Hong CC, Blanco JG, Livingston RB, Davis W, Rae JM, Yeh IT, Hutchins LF, Ravdin PM, Martino S, Lyss AP, Osborne CK, Abeloff MD, et al. Nitric oxide synthase variants and disease-free survival among treated and untreated breast cancer patients in a Southwest Oncology Group clinical trial. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5258-66. PMID 19671875 DOI: 10.1158/1078-0432.Ccr-09-0685 |
0.332 |
|
| 2009 |
Zhang J, Blanco JG. Identification of the promoter of human carbonyl reductase 3 (CBR3) and impact of common promoter polymorphisms on hepatic CBR3 mRNA expression. Pharmaceutical Research. 26: 2209-15. PMID 19590938 DOI: 10.1007/S11095-009-9936-9 |
0.372 |
|
| 2009 |
Gonzalez-Covarrubias V, Zhang J, Kalabus JL, Relling MV, Blanco JG. Pharmacogenetics of human carbonyl reductase 1 (CBR1) in livers from black and white donors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 400-7. PMID 19022938 DOI: 10.1124/Dmd.108.024547 |
0.724 |
|
| 2009 |
Kuptsova-Clarkson N, Ambrosone C, Weiss J, Baer MR, Sucheston L, Zirpoli G, Kopecky K, Ford LA, Blanco J, Wetzler M, Moysich K. XPD DNA Nucleotide Excision Repair (NER) Gene Polymorphisms Associated with DNA Repair Deficiency May Predict Better Treatment Outcomes in Secondary Acute Myeloid Leukemia (AML). Blood. 114: 168-168. DOI: 10.1182/Blood.V114.22.168.168 |
0.368 |
|
| 2008 |
Blanco JG, Leisenring WM, Gonzalez-Covarrubias VM, Kawashima TI, Davies SM, Relling MV, Robison LL, Sklar CA, Stovall M, Bhatia S. Genetic polymorphisms in the carbonyl reductase 3 gene CBR3 and the NAD(P)H:quinone oxidoreductase 1 gene NQO1 in patients who developed anthracycline-related congestive heart failure after childhood cancer. Cancer. 112: 2789-95. PMID 18457324 DOI: 10.1002/Cncr.23534 |
0.441 |
|
| 2008 |
Gonzalez-Covarrubias V, Kalabus JL, Blanco JG. Inhibition of polymorphic human carbonyl reductase 1 (CBR1) by the cardioprotectant flavonoid 7-monohydroxyethyl rutoside (monoHER). Pharmaceutical Research. 25: 1730-4. PMID 18449627 DOI: 10.1007/S11095-008-9592-5 |
0.726 |
|
| 2007 |
Lakhman SS, Chen X, Gonzalez-Covarrubias V, Schuetz EG, Blanco JG. Functional characterization of the promoter of human carbonyl reductase 1 (CBR1). Role of XRE elements in mediating the induction of CBR1 by ligands of the aryl hydrocarbon receptor. Molecular Pharmacology. 72: 734-43. PMID 17569794 DOI: 10.1124/Mol.107.035550 |
0.348 |
|
| 2007 |
Weiss JR, Baer MR, Ambrosone CB, Blanco JG, Hutson A, Ford LA, Moysich KB. Concordance of pharmacogenetic polymorphisms in tumor and germ line DNA in adult patients with acute myeloid leukemia. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 1038-41. PMID 17507636 DOI: 10.1158/1055-9965.Epi-06-0964 |
0.357 |
|
| 2007 |
Gonzalez-Covarrubias V, Ghosh D, Lakhman SS, Pendyala L, Blanco JG. A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 973-80. PMID 17344335 DOI: 10.1124/Dmd.107.014779 |
0.362 |
|
| 2006 |
Aplenc R, Blanco J, Leisenring W, Davies S, Relling M, Robison L, Sklar C, Stovall M, Bhatia S. Polymorphisms in candidate genes in patients with congestive heart failure (CHF) after childhood cancer: A Report from the Childhood Cancer Survivor Study (CCSS). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 9004. PMID 27954251 DOI: 10.1200/Jco.2006.24.18_Suppl.9004 |
0.374 |
|
| 2006 |
Choi JY, Nowell SA, Blanco JG, Ambrosone CB. The role of genetic variability in drug metabolism pathways in breast cancer prognosis Pharmacogenomics. 7: 613-624. PMID 16753008 DOI: 10.2217/14622416.7.4.613 |
0.314 |
|
| 2006 |
Covarrubias VG, Lakhman SS, Forrest A, Relling MV, Blanco JG. Higher activity of polymorphic NAD(P)H:quinone oxidoreductase in liver cytosols from blacks compared to whites. Toxicology Letters. 164: 249-58. PMID 16478651 DOI: 10.1016/J.Toxlet.2006.01.004 |
0.331 |
|
| 2006 |
Weiss JR, Baer MR, Ambrosone CB, Blanco JG, Hutson A, Ford LA, Moysich KB. High Concordance between Pharmacogenetic Analysis of Bone Marrow and Buccal Cell Samples in Acute Myeloid Leukemia. Blood. 108: 2364-2364. DOI: 10.1182/Blood.V108.11.2364.2364 |
0.357 |
|
| 2005 |
Lakhman SS, Ghosh D, Blanco JG. Functional significance of a natural allelic variant of human carbonyl reductase 3 (CBR3). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 254-7. PMID 15537833 DOI: 10.1124/Dmd.104.002006 |
0.339 |
|
| 2004 |
Blanco JG, Edick MJ, Relling MV. Etoposide induces chimeric Mll gene fusions. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 173-5. PMID 14630694 DOI: 10.1096/Fj.03-0638Fje |
0.307 |
|
| 2002 |
Blanco JG, Edick MJ, Hancock ML, Winick NJ, Dervieux T, Amylon MD, Bash RO, Behm FG, Camitta BM, Pui CH, Raimondi SC, Relling MV. Genetic polymorphisms in CYP3A5, CYP3A4 and NQO1 in children who developed therapy-related myeloid malignancies. Pharmacogenetics. 12: 605-11. PMID 12439220 DOI: 10.1097/00008571-200211000-00004 |
0.343 |
|
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