Tian-Li Wang - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Oncology, Pathology, Molecular Biology

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Douville C, Lahouel K, Kuo A, Grant H, Avigdor BE, Curtis SD, Summers M, Cohen JD, Wang Y, Mattox A, Dudley J, Dobbyn L, Popoli M, Ptak J, Nehme N, ... ... Wang TL, et al. Machine learning to detect the SINEs of cancer. Science Translational Medicine. 16: eadi3883. PMID 38266106 DOI: 10.1126/scitranslmed.adi3883  0.467
2023 Mandal J, Yu ZC, Shih IM, Wang TL. ARID1A loss activates MAPK signaling via DUSP4 downregulation. Journal of Biomedical Science. 30: 94. PMID 38071325 DOI: 10.1186/s12929-023-00985-5  0.322
2023 Kinose Y, Xu H, Kim H, Kumar S, Shan X, George E, Wang X, Medvedev S, Ferman B, Gitto SB, Whicker M, D'Andrea K, Wubbenhorst B, Hallberg D, O'Connor M, ... ... Wang TL, et al. Dual blockade of BRD4 and ATR/WEE1 pathways exploits loss in clear cell ovarian cancer. Research Square. PMID 37841875 DOI: 10.21203/rs.3.rs-3314138/v1  0.305
2023 Yu ZC, Li T, Tully E, Huang P, Chen CN, Oberdoerffer P, Gaillard S, Shih IM, Wang TL. Temozolomide sensitizes ARID1A-mutated cancers to PARP inhibitors. Cancer Research. PMID 37306706 DOI: 10.1158/0008-5472.CAN-22-3646  0.34
2022 Wang Y, Huang P, Wang BG, Murdock T, Cope L, Hsu FC, Wang TL, Shih IM. Spatial transcriptomic analysis of ovarian cancer precursors reveals reactivation of IGFBP2 during pathogenesis. Cancer Research. PMID 36206311 DOI: 10.1158/0008-5472.CAN-22-1620  0.328
2022 Mandal J, Mandal P, Wang TL, Shih IM. Treating ARID1A mutated cancers by harnessing synthetic lethality and DNA damage response. Journal of Biomedical Science. 29: 71. PMID 36123603 DOI: 10.1186/s12929-022-00856-5  0.342
2021 Park Y, Jung JG, Yu ZC, Asaka R, Shen W, Wang Y, Jung WH, Tomaszewski A, Shimberg G, Chen Y, Parimi V, Gaillard S, Shih IM, Wang TL. A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 1505-1512. PMID 34376780 DOI: 10.1038/s41374-021-00624-3  0.319
2021 Park Y, Jung JG, Yu ZC, Asaka R, Shen W, Wang Y, Jung WH, Tomaszewski A, Shimberg G, Chen Y, Parimi V, Gaillard S, Shih IM, Wang TL. A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 1505-1512. PMID 34376780 DOI: 10.1038/s41374-021-00624-3  0.319
2021 Park Y, Jung JG, Yu ZC, Asaka R, Shen W, Wang Y, Jung WH, Tomaszewski A, Shimberg G, Chen Y, Parimi V, Gaillard S, Shih IM, Wang TL. A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 1505-1512. PMID 34376780 DOI: 10.1038/s41374-021-00624-3  0.319
2021 Park Y, Jung JG, Yu ZC, Asaka R, Shen W, Wang Y, Jung WH, Tomaszewski A, Shimberg G, Chen Y, Parimi V, Gaillard S, Shih IM, Wang TL. A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 1505-1512. PMID 34376780 DOI: 10.1038/s41374-021-00624-3  0.319
2021 Park Y, Jung JG, Yu ZC, Asaka R, Shen W, Wang Y, Jung WH, Tomaszewski A, Shimberg G, Chen Y, Parimi V, Gaillard S, Shih IM, Wang TL. A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 1505-1512. PMID 34376780 DOI: 10.1038/s41374-021-00624-3  0.319
2021 Park Y, Jung JG, Yu ZC, Asaka R, Shen W, Wang Y, Jung WH, Tomaszewski A, Shimberg G, Chen Y, Parimi V, Gaillard S, Shih IM, Wang TL. A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 1505-1512. PMID 34376780 DOI: 10.1038/s41374-021-00624-3  0.319
2021 Park Y, Jung JG, Yu ZC, Asaka R, Shen W, Wang Y, Jung WH, Tomaszewski A, Shimberg G, Chen Y, Parimi V, Gaillard S, Shih IM, Wang TL. A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 1505-1512. PMID 34376780 DOI: 10.1038/s41374-021-00624-3  0.319
2021 Park Y, Jung JG, Yu ZC, Asaka R, Shen W, Wang Y, Jung WH, Tomaszewski A, Shimberg G, Chen Y, Parimi V, Gaillard S, Shih IM, Wang TL. A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 1505-1512. PMID 34376780 DOI: 10.1038/s41374-021-00624-3  0.319
2021 Park Y, Jung JG, Yu ZC, Asaka R, Shen W, Wang Y, Jung WH, Tomaszewski A, Shimberg G, Chen Y, Parimi V, Gaillard S, Shih IM, Wang TL. A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 1505-1512. PMID 34376780 DOI: 10.1038/s41374-021-00624-3  0.319
2021 Park Y, Jung JG, Yu ZC, Asaka R, Shen W, Wang Y, Jung WH, Tomaszewski A, Shimberg G, Chen Y, Parimi V, Gaillard S, Shih IM, Wang TL. A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 1505-1512. PMID 34376780 DOI: 10.1038/s41374-021-00624-3  0.319
2021 Park Y, Jung JG, Yu ZC, Asaka R, Shen W, Wang Y, Jung WH, Tomaszewski A, Shimberg G, Chen Y, Parimi V, Gaillard S, Shih IM, Wang TL. A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 1505-1512. PMID 34376780 DOI: 10.1038/s41374-021-00624-3  0.319
2021 Park Y, Jung JG, Yu ZC, Asaka R, Shen W, Wang Y, Jung WH, Tomaszewski A, Shimberg G, Chen Y, Parimi V, Gaillard S, Shih IM, Wang TL. A novel human endometrial epithelial cell line for modeling gynecological diseases and for drug screening. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 1505-1512. PMID 34376780 DOI: 10.1038/s41374-021-00624-3  0.319
2020 Li L, Yue P, Song Q, Yen TT, Asaka S, Wang TL, Beavis AL, Fader AN, Jiao Y, Yuan G, Shih IM, Song Y. Genome-wide mutation analysis in precancerous lesions of endometrial carcinoma. The Journal of Pathology. PMID 33016334 DOI: 10.1002/path.5566  0.32
2020 Shih IM, Wang Y, Wang TL. The Origin of Ovarian Cancer Species and Precancerous Landscape. The American Journal of Pathology. PMID 33011111 DOI: 10.1016/j.ajpath.2020.09.006  0.335
2020 Shen YA, Hong J, Asaka R, Asaka S, Hsu FC, Suryo Rahmanto Y, Jung JG, Chen YW, Yen TT, Tomaszewski A, Zhang C, Attarwala N, DeMarzo AM, Davidson B, Chuang CM, ... ... Wang TL, et al. Inhibition of the MYC-regulated glutaminase metabolic axis is an effective synthetic lethal approach for treating chemoresistant cancers. Cancer Research. PMID 32859605 DOI: 10.1158/0008-5472.Can-19-3971  0.427
2020 Pisanic TR, Wang Y, Sun H, Considine M, Li L, Wang TH, Wang TL, Shih IM. The methylomic landscape of fallopian tube lesions associated with ovarian high-grade serous carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32817081 DOI: 10.1158/1078-0432.Ccr-20-0270  0.319
2020 Suryo Rahmanto Y, Shen W, Shi X, Chen X, Yu Y, Yu ZC, Miyamoto T, Lee MH, Singh V, Asaka R, Shimberg G, Vitolo MI, Martin SS, Wirtz D, Drapkin R, ... ... Wang TL, et al. Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming. Nature Communications. 11: 2717. PMID 32483112 DOI: 10.1038/S41467-020-16416-0  0.339
2020 Douville C, Cohen JD, Ptak J, Popoli M, Schaefer J, Silliman N, Dobbyn L, Schoen RE, Tie J, Gibbs P, Goggins M, Wolfgang CL, Wang TL, Shih IM, Karchin R, et al. Assessing aneuploidy with repetitive element sequencing. Proceedings of the National Academy of Sciences of the United States of America. PMID 32075918 DOI: 10.1073/Pnas.1910041117  0.508
2020 Anchoori RK, Tan M, Tseng SH, Peng S, Soong RS, Algethami A, Foran P, Das S, Wang C, Wang TL, Liang H, Hung CF, Roden RBS. Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties. Plos One. 15: e0227727. PMID 31940398 DOI: 10.1371/Journal.Pone.0227727  0.355
2019 Chui MH, Kjaer SK, Frederiksen K, Hannibal CG, Wang TL, Vang R, Shih IM. -mutated ovarian serous borderline tumors are at relatively low risk for progression to serous carcinoma. Oncotarget. 10: 6870-6878. PMID 31839880 DOI: 10.18632/Oncotarget.27326  0.4
2019 Yu Y, Suryo Rahmanto Y, Shen YA, Ardighieri L, Davidson B, Gaillard S, Ayhan A, Shi X, Xuan J, Wang TL, Shih IM. Spleen tyrosine kinase activity regulates epidermal growth factor receptor signaling pathway in ovarian cancer. Ebiomedicine. PMID 31492560 DOI: 10.1016/J.Ebiom.2019.08.055  0.306
2019 Nguyen T, Kirsch BJ, Asaka R, Nabi K, Quinones A, Tan J, Antonio MJ, Camelo F, Li T, Nguyen S, Hoang G, Nguyen K, Udupa S, Sazeides C, Shen YA, ... ... Wang TL, et al. Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cancer. Cell Reports. 27: 491-501.e6. PMID 30970252 DOI: 10.1016/J.Celrep.2019.03.036  0.332
2019 Hu Z, Zhou J, Jiang J, Yuan J, Zhang Y, Wei X, Loo N, Wang Y, Pan Y, Zhang T, Zhong X, Long M, Montone KT, Tanyi JL, Fan Y, ... Wang TL, et al. Genomic characterization of genes encoding histone acetylation modulator proteins identifies therapeutic targets for cancer treatment. Nature Communications. 10: 733. PMID 30760718 DOI: 10.1038/S41467-019-08554-X  0.424
2019 Whelan S, Ophir E, Kotturi MF, Levy O, Ganguly S, Leung L, Vaknin I, Kumar S, Dassa L, Hansen K, Bernados D, Murter B, Soni A, Taube JM, Fader AN, ... Wang TL, et al. PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8 T-cell Function. Cancer Immunology Research. PMID 30659054 DOI: 10.1158/2326-6066.Cir-18-0442  0.566
2018 Wu RC, Wang P, Lin SF, Zhang M, Song Q, Chu T, Wang BG, Kurman RJ, Vang R, Kinzler K, Tomasetti C, Jiao Y, Shih IM, Wang TL. Genomic landscape and evolutionary trajectories of ovarian cancer early precursor lesions. The Journal of Pathology. PMID 30560554 DOI: 10.1002/Path.5219  0.578
2018 Asaka S, Yen TT, Wang TL, Shih IM, Gaillard S. T cell-inflamed phenotype and increased Foxp3 expression in infiltrating T-cells of mismatch-repair deficient endometrial cancers. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 30401949 DOI: 10.1038/S41379-018-0172-X  0.348
2018 Visvanathan K, Shaw P, May BJ, Bahadirli-Talbot A, Kaushiva A, Risch H, Narod S, Wang TL, Parkash V, Vang R, Levine DA, Soslow R, Kurman R, Shih IM. Fallopian tube lesions in women at high risk for ovarian cancer: A multicenter study. Cancer Prevention Research (Philadelphia, Pa.). PMID 30232083 DOI: 10.1158/1940-6207.Capr-18-0009  0.32
2018 Stone ML, Chiappinelli KB, Li H, Murphy LM, Travers ME, Topper MJ, Mathios D, Lim M, Shih IM, Wang TL, Hung CF, Bhargava V, Wiehagen KR, Cowley GS, Bachman KE, et al. Reply to Haffner et al.: DNA hypomethylation renders tumors more immunogenic. Proceedings of the National Academy of Sciences of the United States of America. PMID 30181297 DOI: 10.1073/Pnas.1811015115  0.374
2018 Yen TT, Miyamoto T, Asaka S, Chui MH, Wang Y, Lin SF, Stone RL, Fader AN, Asaka R, Kashima H, Shiozawa T, Wang TL, Shih IM, Tanner EJ. Loss of ARID1A expression in endometrial samplings is associated with the risk of endometrial carcinoma. Gynecologic Oncology. 150: 426-431. PMID 30126589 DOI: 10.1016/J.Ygyno.2018.06.025  0.423
2018 Pisanic TR, Cope L, Lin SF, Yen TT, Athamanolap P, Asaka R, Nakayama K, Fader AN, Wang TH, Shih IM, Wang TL. Methylomic analysis of ovarian cancers identifies tumor-specific alterations readily detectable in early precursor lesions. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30108103 DOI: 10.1158/1078-0432.Ccr-18-1199  0.38
2018 Yu Y, Suryo Rahmanto Y, Lee MH, Wu PH, Phillip JM, Huang CH, Vitolo MI, Gaillard S, Martin SS, Wirtz D, Shih IM, Wang TL. Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway. Oncogene. PMID 29643476 DOI: 10.1038/S41388-018-0241-0  0.429
2018 Noë M, Ayhan A, Wang TL, Shih IM. Independent development of endometrial epithelium and stroma within the same endometriosis. The Journal of Pathology. PMID 29604057 DOI: 10.1002/Path.5082  0.335
2018 Fukumoto T, Park PH, Wu S, Fatkhutdinov N, Karakashev S, Nacarelli T, Kossenkov AV, Speicher DW, Jean S, Zhang L, Wang TL, Shih IM, Conejo-Garcia JR, Bitler BG, Zhang R. Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer. Cell Reports. 22: 3393-3400. PMID 29590609 DOI: 10.1016/J.Celrep.2018.03.019  0.444
2018 Wang Y, Li L, Douville C, Cohen JD, Yen TT, Kinde I, Sundfelt K, Kjær SK, Hruban RH, Shih IM, Wang TL, Kurman RJ, Springer S, Ptak J, Popoli M, et al. Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers. Science Translational Medicine. 10. PMID 29563323 DOI: 10.1126/Scitranslmed.Aap8793  0.474
2018 Cohen JD, Li L, Wang Y, Thoburn C, Afsari B, Danilova L, Douville C, Javed AA, Wong F, Mattox A, Hruban RH, Wolfgang CL, Goggins MG, Dal Molin M, Wang TL, et al. Detection and localization of surgically resectable cancers with a multi-analyte blood test. Science (New York, N.Y.). PMID 29348365 DOI: 10.1126/Science.Aar3247  0.462
2018 Rahmanto YS, Shi X, Shen W, Miyamoto T, Yu Y, Chen X, Lee M, Singh V, Vitolo MI, Wirtz D, Drapkin R, Xuan J, Shih I, Wang T. Abstract 2493: Inactivation of ARID1A-SWI/SNF complex alters chromatin compactness at enhancer regions and affects transcription of key tumor signaling circuitry Cancer Research. 78: 2493-2493. DOI: 10.1158/1538-7445.Am2018-2493  0.457
2018 Shen Y, Jung J, Rahmanto YS, Selleri L, Shih I, Chuang C, Wang T. Abstract 1966: A novel small-molecule compound targeting PBX1-DNA interaction impedes cancer cell survival and carboplatin resistance Cancer Research. 78: 1966-1966. DOI: 10.1158/1538-7445.Am2018-1966  0.399
2018 Wang Y, Li L, Douville C, Cohen JD, Yen TT, Kinde I, Sundfelt K, Kjær SK, Hruban RH, Shih IM, Wang T, Kurman RJ, Springer S, Ptak J, Popoli M, et al. Evaluation of liquid from the papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers Obstetrical & Gynecological Survey. 73: 463-464. DOI: 10.1097/01.Ogx.0000542325.60681.A3  0.304
2017 Ojalvo LS, Thompson ED, Wang TL, Meeker AK, Shih IM, Fader AN, Cimino-Mathews AM, Emens LA. Tumor-Associated Macrophages and the Tumor Immune Microenvironment of Primary and Recurrent Epithelial Ovarian Cancer (EOC). Human Pathology. PMID 29288043 DOI: 10.1016/J.Humpath.2017.12.010  0.344
2017 Visvanathan K, Wang TL, Shih IM. Precancerous Lesions of Ovarian Cancer-A US Perspective. Journal of the National Cancer Institute. PMID 29281080 DOI: 10.1093/Jnci/Djx269  0.339
2017 Fan Q, Cai Q, Li P, Wang W, Wang J, Gerry E, Wang TL, Shih IM, Nephew KP, Xu Y. The novel ZIP4 regulation and its role in ovarian cancer. Oncotarget. 8: 90090-90107. PMID 29163813 DOI: 10.18632/Oncotarget.21435  0.331
2017 Wu RC, Veras E, Lin J, Gerry E, Bahadirli-Talbott A, Baras A, Ayhan A, Shih IM, Wang TL. Elucidating the pathogenesis of synchronous and metachronous tumors in a woman with endometrioid carcinomas using a whole-exome sequencing approach. Cold Spring Harbor Molecular Case Studies. 3. PMID 29162652 DOI: 10.1101/mcs.a001693  0.607
2017 Labidi-Galy SI, Papp E, Hallberg D, Niknafs N, Adleff V, Noe M, Bhattacharya R, Novak M, Jones S, Phallen J, Hruban CA, Hirsch MS, Lin DI, Schwartz L, Maire CL, ... ... Wang TL, et al. High grade serous ovarian carcinomas originate in the fallopian tube. Nature Communications. 8: 1093. PMID 29061967 DOI: 10.1038/S41467-017-00962-1  0.439
2017 Xing D, Rahmanto YS, Zeppernick F, Hannibal CG, Kjaer SK, Vang R, Shih IM, Wang TL. Mutation of NRAS is a Rare Genetic Event in Ovarian Low-Grade Serous Carcinoma. Human Pathology. PMID 28873354 DOI: 10.1016/J.Humpath.2017.08.021  0.387
2017 Jiang RT, Yemelyanova A, Xing D, Anchoori RK, Hamazaki J, Murata S, Seidman JD, Wang TL, Roden RBS. Early and consistent overexpression of ADRM1 in ovarian high-grade serous carcinoma. Journal of Ovarian Research. 10: 53. PMID 28784174 DOI: 10.1186/s13048-017-0347-y  0.301
2017 Anglesio MS, Papadopoulos N, Ayhan A, Nazeran TM, Noë M, Horlings HM, Lum A, Jones S, Senz J, Seckin T, Ho J, Wu RC, Lac V, Ogawa H, Tessier-Cloutier B, ... ... Wang TL, et al. Cancer-Associated Mutations in Endometriosis without Cancer. The New England Journal of Medicine. 376: 1835-1848. PMID 28489996 DOI: 10.1056/Nejmoa1614814  0.682
2017 Ojalvo LS, Thompson ED, Wang T, Meeker AK, Shih I, Fader AN, Cimino-Mathews A, Emens LA. Abstract 3991: Profiling the immune tumor microenvironment in primary and recurrent epithelial ovarian cancer Cancer Research. 77: 3991-3991. DOI: 10.1158/1538-7445.Am2017-3991  0.377
2017 Nickles Fader A, Wang Y, Papadapoulos N, Stone R, Wang T, Tanner E, Shih I, Vogelstein B. Detection of tumor-derived DNA with combination Pap smear and plasma testing in women with primary ovarian cancer: A potential screening test on the horizon? Gynecologic Oncology. 145: 24-25. DOI: 10.1016/J.Ygyno.2017.03.071  0.423
2016 Ayhan A, Kuhn E, Wu RC, Ogawa H, Bahadirli-Talbott A, Mao TL, Sugimura H, Shih IM, Wang TL. CCNE1 copy-number gain and overexpression identify ovarian clear cell carcinoma with a poor prognosis. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 27767100 DOI: 10.1038/modpathol.2016.160  0.634
2016 Jung JG, Shih IM, Park JT, Gerry E, Kim TH, Ayhan A, Handschuh K, Davidson B, Nickles Fader A, Selleri L, Wang TL. Ovarian cancer chemoresistance relies on the the stem cell reprogramming factor PBX1. Cancer Research. PMID 27590741 DOI: 10.1158/0008-5472.Can-16-0980  0.442
2016 Kuhn E, Wang TL, Doberstein K, Bahadirli-Talbott A, Ayhan A, Sehdev AS, Drapkin R, Kurman RJ, Shih IM. CCNE1 amplification and centrosome number abnormality in serous tubal intraepithelial carcinoma: further evidence supporting its role as a precursor of ovarian high-grade serous carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 27443516 DOI: 10.1038/Modpathol.2016.101  0.356
2016 Suryo Rahmanto Y, Jung JG, Wu RC, Kobayashi Y, Heaphy CM, Meeker AK, Wang TL, Shih IM. Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells. The Journal of Biological Chemistry. PMID 26953344 DOI: 10.1074/Jbc.M115.707612  0.641
2016 Herlinger AL, Gao M, Wu R, Wang T, Rangel LBA, Shih I. Abstract A80: NAC1 attenuates BCL6 negative autoregulation and functions as a BCL6 coactivator of FOXQ1 transcription in ovarian cancer (OVCA). Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Ovca15-A80  0.405
2016 Jung J, Kim T, Gerry E, Kuan J, Ayhan A, Davidson B, Shih I, Wang T. Abstract A32: PBX1, a transcriptional regulator, promotes stemness and chemoresistance in ovarian cancer. Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Ovca15-A32  0.452
2015 Ayhan A, Mao TL, Suryo Rahmanto Y, Zeppernick F, Ogawa H, Wu RC, Wang TL, Shih IeM. Increased proliferation in atypical hyperplasia/endometrioid intraepithelial neoplasia of the endometrium with concurrent inactivation of ARID1A and PTEN tumour suppressors. The Journal of Pathology. Clinical Research. 1: 186-93. PMID 27499903 DOI: 10.1002/cjp2.22  0.589
2015 Kashima H, Wu RC, Wang Y, Sinno AK, Miyamoto T, Shiozawa T, Wang TL, Fader AN, Shih IM. Laminin C1 expression by uterine carcinoma cells is associated with tumor progression. Gynecologic Oncology. PMID 26343160 DOI: 10.1016/J.Ygyno.2015.08.025  0.623
2015 Kobayashi Y, Kashima H, Wu RC, Jung JG, Kuan JC, Gu J, Xuan J, Sokoll L, Visvanathan K, Shih IM, Wang TL. Mevalonate Pathway Antagonist Inhibits Proliferation of Serous Tubal Intraepithelial Carcinoma and Ovarian Carcinoma in Mouse Models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26109099 DOI: 10.1158/1078-0432.Ccr-14-3368  0.634
2015 Chui MH, Wang Y, Wu RC, Seidman J, Kurman RJ, Wang TL, Shih IeM. Loss of ALDH1A1 expression is an early event in the pathogenesis of ovarian high-grade serous carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 28: 437-45. PMID 25216223 DOI: 10.1038/Modpathol.2014.89  0.643
2015 Jung JG, Park JT, Stoeck A, Hussain T, Wu R, Shih I, Wang T. Abstract B15: Targeting PBX1 signaling to sensitize carboplatin cytotoxicity in ovarian cancer Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-B15  0.458
2014 Jung JG, Stoeck A, Guan B, Wu RC, Zhu H, Blackshaw S, Shih IeM, Wang TL. Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer. Plos Genetics. 10: e1004751. PMID 25356737 DOI: 10.1371/journal.pgen.1004751  0.643
2014 Guan B, Rahmanto YS, Wu RC, Wang Y, Wang Z, Wang TL, Shih IeM. Roles of deletion of Arid1a, a tumor suppressor, in mouse ovarian tumorigenesis. Journal of the National Cancer Institute. 106. PMID 24899687 DOI: 10.1093/jnci/dju146  0.633
2014 Wu RC, Wang TL, Shih IeM. The emerging roles of ARID1A in tumor suppression. Cancer Biology & Therapy. 15: 655-64. PMID 24618703 DOI: 10.4161/cbt.28411  0.643
2014 Bettegowda C, Sausen M, Leary RJ, Kinde I, Wang Y, Agrawal N, Bartlett BR, Wang H, Luber B, Alani RM, Antonarakis ES, Azad NS, Bardelli A, Brem H, Cameron JL, ... ... Wang TL, et al. Detection of circulating tumor DNA in early- and late-stage human malignancies. Science Translational Medicine. 6: 224ra24. PMID 24553385 DOI: 10.1126/Scitranslmed.3007094  0.578
2014 Wu RC, Ayhan A, Maeda D, Kim KR, Clarke BA, Shaw P, Chui MH, Rosen B, Shih IeM, Wang TL. Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynaecological malignancy. The Journal of Pathology. 232: 473-81. PMID 24338723 DOI: 10.1002/Path.4315  0.672
2014 Gao M, Wu RC, Herlinger AL, Yap K, Kim JW, Wang TL, Shih IeM. Identification of the NAC1-regulated genes in ovarian cancer. The American Journal of Pathology. 184: 133-40. PMID 24200849 DOI: 10.1016/J.Ajpath.2013.09.024  0.726
2013 Mao TL, Ardighieri L, Ayhan A, Kuo KT, Wu CH, Wang TL, Shih IeM. Loss of ARID1A expression correlates with stages of tumor progression in uterine endometrioid carcinoma. The American Journal of Surgical Pathology. 37: 1342-8. PMID 24076775 DOI: 10.1097/Pas.0B013E3182889Dc3  0.347
2013 Yap KL, Sysa-Shah P, Bolon B, Wu RC, Gao M, Herlinger AL, Wang F, Faiola F, Huso D, Gabrielson K, Wang TL, Wang J, Shih IeM. Loss of NAC1 expression is associated with defective bony patterning in the murine vertebral axis. Plos One. 8: e69099. PMID 23922682 DOI: 10.1371/Journal.Pone.0069099  0.67
2013 Killela PJ, Reitman ZJ, Jiao Y, Bettegowda C, Agrawal N, Diaz LA, Friedman AH, Friedman H, Gallia GL, Giovanella BC, Grollman AP, He TC, He Y, Hruban RH, Jallo GI, ... ... Wang TL, et al. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proceedings of the National Academy of Sciences of the United States of America. 110: 6021-6. PMID 23530248 DOI: 10.1093/Neuonc/Nou206.18  0.55
2013 Cope L, Wu RC, Shih IeM, Wang TL. High level of chromosomal aberration in ovarian cancer genome correlates with poor clinical outcome. Gynecologic Oncology. 128: 500-5. PMID 23200914 DOI: 10.1016/j.ygyno.2012.11.031  0.588
2013 Wu R, Guan B, Kobayashi Y, Wang T, Shih I. Abstract A63: Rsf-1, a chromatin remodeling protein, interacts with shelterin protein hRap1 and induces telomere shortening Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A63  0.375
2013 Guan B, Wang T, Shih I. Abstract LB-259: Arid1a loss in collaboration with PI3K pathway activation leads to ovarian tumorigenesis in mouse. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-259  0.421
2013 Davidson B, Abeler VM, Førsund M, Holth A, Shih I, Kristensen GB, Chen L, Yang Y, Wang T. Abstract 401: Gene expression signatures differentiate primary and metastatic uterine leiomyosarcoma. Cancer Research. 73: 401-401. DOI: 10.1158/1538-7445.Am2013-401  0.385
2012 Gao M, Shih IeM, Wang TL. The role of forkhead box Q1 transcription factor in ovarian epithelial carcinomas. International Journal of Molecular Sciences. 13: 13881-93. PMID 23203039 DOI: 10.3390/ijms131113881  0.337
2012 Kuhn E, Wu RC, Guan B, Wu G, Zhang J, Wang Y, Song L, Yuan X, Wei L, Roden RB, Kuo KT, Nakayama K, Clarke B, Shaw P, Olvera N, ... ... Wang TL, et al. Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses. Journal of the National Cancer Institute. 104: 1503-13. PMID 22923510 DOI: 10.1093/Jnci/Djs345  0.592
2012 Kuhn E, Kurman RJ, Soslow RA, Han G, Sehdev AS, Morin PJ, Wang TL, Shih IeM. The diagnostic and biological implications of laminin expression in serous tubal intraepithelial carcinoma. The American Journal of Surgical Pathology. 36: 1826-34. PMID 22892598 DOI: 10.1097/Pas.0B013E31825Ec07A  0.368
2012 Yap KL, Fraley SI, Thiaville MM, Jinawath N, Nakayama K, Wang J, Wang TL, Wirtz D, Shih IeM. NAC1 is an actin-binding protein that is essential for effective cytokinesis in cancer cells. Cancer Research. 72: 4085-96. PMID 22761335 DOI: 10.1158/0008-5472.Can-12-0302  0.621
2012 Thiaville MM, Stoeck A, Chen L, Wu RC, Magnani L, Oidtman J, Shih IeM, Lupien M, Wang TL. Identification of PBX1 target genes in cancer cells by global mapping of PBX1 binding sites. Plos One. 7: e36054. PMID 22567123 DOI: 10.1371/Journal.Pone.0036054  0.632
2012 Chen X, Thiaville MM, Chen L, Stoeck A, Xuan J, Gao M, Shih IeM, Wang TL. Defining NOTCH3 target genes in ovarian cancer. Cancer Research. 72: 2294-303. PMID 22396495 DOI: 10.1158/0008-5472.CAN-11-2181  0.307
2012 Jones S, Wang TL, Kurman RJ, Nakayama K, Velculescu VE, Vogelstein B, Kinzler KW, Papadopoulos N, Shih IM. Low-grade serous carcinomas of the ovary contain very few point mutations Journal of Pathology. 226: 413-420. PMID 22102435 DOI: 10.1002/Path.3967  0.528
2012 Yap KL, Fraley SI, Shah PS, Wang F, Thiaville MM, Jinawath N, Nakayama K, Wang J, Brayton C, Bolon B, Gabrielson K, Wirtz D, Wang T, Shih I. Abstract LB-115: NAC1 is an actin binding protein essential for the cytokinesis of cancer cells and plays a role in the patterning of murine vertebral axis Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-115  0.652
2012 Gaillard S, Stoeck A, Davidson B, Wang T, Shih I. Abstract 815: The role of spleen tyrosine kinase (SYK) in paclitaxel resistant ovarian cancer Cancer Research. 72: 815-815. DOI: 10.1158/1538-7445.Am2012-815  0.338
2012 Kuhn E, Yemelyanova A, Wang T, Kurman R, Shih I. Abstract 5536:TP53andMED12mutations in uterine smooth muscle tumors Cancer Research. 72: 5536-5536. DOI: 10.1158/1538-7445.Am2012-5536  0.401
2011 Guan B, Wang TL, Shih IeM. ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers. Cancer Research. 71: 6718-27. PMID 21900401 DOI: 10.1158/0008-5472.CAN-11-1562  0.353
2011 Fang FM, Li CF, Huang HY, Lai MT, Chen CM, Chiu IW, Wang TL, Tsai FJ, Shih IeM, Sheu JJ. Overexpression of a chromatin remodeling factor, RSF-1/HBXAP, correlates with aggressive oral squamous cell carcinoma. The American Journal of Pathology. 178: 2407-15. PMID 21514451 DOI: 10.1016/J.Ajpath.2011.01.043  0.377
2011 Shih IeM, Panuganti PK, Kuo KT, Mao TL, Kuhn E, Jones S, Velculescu VE, Kurman RJ, Wang TL. Somatic mutations of PPP2R1A in ovarian and uterine carcinomas. The American Journal of Pathology. 178: 1442-7. PMID 21435433 DOI: 10.1016/J.Ajpath.2011.01.009  0.397
2011 Shih IeM, Nakayama K, Wu G, Nakayama N, Zhang J, Wang TL. Amplification of the ch19p13.2 NACC1 locus in ovarian high-grade serous carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 638-45. PMID 21240255 DOI: 10.1038/modpathol.2010.230  0.341
2011 Maeda D, Chen X, Guan B, Nakagawa S, Yano T, Taketani Y, Fukayama M, Wang TL, Shih IeM. Rsf-1 (HBXAP) expression is associated with advanced stage and lymph node metastasis in ovarian clear cell carcinoma. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. 30: 30-5. PMID 21131837 DOI: 10.1097/Pgp.0B013E3181E9A319  0.382
2011 Yap KL, Fraley SI, Thiaville MM, Jinawath N, Nakayama K, Wang J, Wirtz D, Wang T, Shih l. Abstract B18: Identification and characterization of NAC1 as a profilin1/actin-binding protein that is essential for effective cytokinesis in cancer cells Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-B18  0.66
2011 Guan B, Wang T, Shih l. Abstract A45: The tumor suppressor role of ARID1A in gynecologic cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-A45  0.491
2011 Kuhn E, Kurman RJ, Soslow RA, Han G, Wang T, Shih I. Abstract 221:TP53mutations in serous tubal intraepithelial carcinoma, the putative precursor lesion of ovarian high-grade serous carcinoma Cancer Research. 71: 221-221. DOI: 10.1158/1538-7445.Am2011-221  0.398
2011 Stoeck A, Chen X, Shih I, Wang T. Abstract 1987: Identification and characterization of novel Notch3 interacting proteins in ovarian cancer Cancer Research. 71: 1987-1987. DOI: 10.1158/1538-7445.Am2011-1987  0.406
2010 Wang TL, Davidson B, Buckhaults PJ, Huang CS, Poul G. Molecular genetic markers in female reproductive cancers. Journal of Oncology. 2010: 307460. PMID 21541207 DOI: 10.1155/2010/307460  0.362
2010 Sheu JJ, Guan B, Choi JH, Lin A, Lee CH, Hsiao YT, Wang TL, Tsai FJ, Shih IeM. Rsf-1, a chromatin remodeling protein, induces DNA damage and promotes genomic instability. The Journal of Biological Chemistry. 285: 38260-9. PMID 20923775 DOI: 10.1074/Jbc.M110.138735  0.311
2010 Davidson B, Reich R, Trope CG, Wang TL, Shih IeM. New determinates of disease progression and outcome in metastatic ovarian carcinoma. Histology and Histopathology. 25: 1591-609. PMID 20886439  0.308
2010 Jones S, Wang TL, Shih IeM, Mao TL, Nakayama K, Roden R, Glas R, Slamon D, Diaz LA, Vogelstein B, Kinzler KW, Velculescu VE, Papadopoulos N. Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science (New York, N.Y.). 330: 228-31. PMID 20826764 DOI: 10.1126/Science.1196333  0.54
2010 Park JT, Chen X, Tropè CG, Davidson B, Shih IeM, Wang TL. Notch3 overexpression is related to the recurrence of ovarian cancer and confers resistance to carboplatin. The American Journal of Pathology. 177: 1087-94. PMID 20671266 DOI: 10.2353/ajpath.2010.100316  0.323
2010 Jinawath N, Vasoontara C, Jinawath A, Fang X, Zhao K, Yap KL, Guo T, Lee CS, Wang W, Balgley BM, Davidson B, Wang TL, Shih IeM. Oncoproteomic analysis reveals co-upregulation of RELA and STAT5 in carboplatin resistant ovarian carcinoma. Plos One. 5: e11198. PMID 20585448 DOI: 10.1371/Journal.Pone.0011198  0.636
2010 Ueda SM, Yap KL, Davidson B, Tian Y, Murthy V, Wang TL, Visvanathan K, Kuhajda FP, Bristow RE, Zhang H, Shih IeM. Expression of Fatty Acid Synthase Depends on NAC1 and Is Associated with Recurrent Ovarian Serous Carcinomas. Journal of Oncology. 2010: 285191. PMID 20508725 DOI: 10.1155/2010/285191  0.674
2010 Kuhn E, Meeker A, Wang TL, Sehdev AS, Kurman RJ, Shih IeM. Shortened telomeres in serous tubal intraepithelial carcinoma: an early event in ovarian high-grade serous carcinogenesis. The American Journal of Surgical Pathology. 34: 829-36. PMID 20431479 DOI: 10.1097/Pas.0B013E3181Dcede7  0.397
2010 Kuo KT, Mao TL, Chen X, Feng Y, Nakayama K, Wang Y, Glas R, Ma MJ, Kurman RJ, Shih IeM, Wang TL. DNA copy numbers profiles in affinity-purified ovarian clear cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 1997-2008. PMID 20233889 DOI: 10.1158/1078-0432.Ccr-09-2105  0.421
2010 Zhang Y, Shih I, Wang T, Wang T. A novel quantum dot based nanoassay for high resolution copy number variation detection and DNA methylation quantification Clinical Cancer Research. 16. DOI: 10.1158/Diag-10-A17  0.336
2010 Kuhn E, Park JT, Davidson B, Kurman RJ, Shih I, Wang T. Abstract LB-50: Overexpression ofPBX1is associated with recurrence and worse clinical outcome in patients with recurrent ovarian high-grade serous carcinoma Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-50  0.379
2010 Kuhn E, Meeker A, Wang T, Sehdev AS, Kurman RJ, Shih I. Abstract LB-343: Shortened telomeres in serous tubal intraepithelial carcinoma: An early event in ovarian high-grade serous carcinogenesis Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-343  0.388
2010 Thiaville MM, Wang T, Shih I, Chen L, Xiong J, Xuan JJ. Abstract 4871: Genomic amplifications in ovarian carcinoma are associated with specific histone modifications Cancer Research. 70: 4871-4871. DOI: 10.1158/1538-7445.Am10-4871  0.418
2009 Duncan CG, Leary RJ, Lin JC, Cummins J, Di C, Schaefer CF, Wang TL, Riggins GJ, Edwards J, Bigner D, Kopelovich L, Vogelstein B, Kinzler KW, Velculescu VE, Yan H. Identification of microbial DNA in human cancer. Bmc Medical Genomics. 2: 22. PMID 19426505 DOI: 10.1186/1755-8794-2-22  0.773
2009 Kuo KT, Guan B, Feng Y, Mao TL, Chen X, Jinawath N, Wang Y, Kurman RJ, Shih IeM, Wang TL. Analysis of DNA copy number alterations in ovarian serous tumors identifies new molecular genetic changes in low-grade and high-grade carcinomas. Cancer Research. 69: 4036-42. PMID 19383911 DOI: 10.1158/0008-5472.CAN-08-3913  0.331
2009 Kuo KT, Mao TL, Jones S, Veras E, Ayhan A, Wang TL, Glas R, Slamon D, Velculescu VE, Kuman RJ, Shih IeM. Frequent activating mutations of PIK3CA in ovarian clear cell carcinoma. The American Journal of Pathology. 174: 1597-601. PMID 19349352 DOI: 10.2353/ajpath.2009.081000  0.343
2009 Jinawath N, Vasoontara C, Yap KL, Thiaville MM, Nakayama K, Wang TL, Shih IM. NAC-1, a potential stem cell pluripotency factor, contributes to paclitaxel resistance in ovarian cancer through inactivating Gadd45 pathway. Oncogene. 28: 1941-8. PMID 19305429 DOI: 10.1038/Onc.2009.37  0.664
2009 Choi JH, Sheu JJ, Guan B, Jinawath N, Markowski P, Wang TL, Shih IeM. Functional analysis of 11q13.5 amplicon identifies Rsf-1 (HBXAP) as a gene involved in paclitaxel resistance in ovarian cancer. Cancer Research. 69: 1407-15. PMID 19190325 DOI: 10.1158/0008-5472.CAN-08-3602  0.323
2009 Liu X, Wang X, Tedjarati S, Wang T, Hsieh H. Abstract C234: A novel microtubule inhibitor BPR0L075 overcomes paclitaxel resistance in ovarian cancer cell lines Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-C234  0.397
2009 Kuo KT, Guan B, Feng Y, Mao TL, Chen X, Jinawath N, Wang Y, Kurman RJ, Shih IM, Wang T. Analysis of DNA copy number alterations in ovarian serous tumors identifies new molecular genetic changes in low-grade and high-grade carcinomas (Cancer Research (2009) 69, (4036-42)) Cancer Research. 69. DOI: 10.1158/0008-5472.Can-69-12-Cor2  0.412
2008 Park JT, Shih IeM, Wang TL. Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer. Cancer Research. 68: 8852-60. PMID 18974129 DOI: 10.1158/0008-5472.CAN-08-0517  0.335
2008 Leary RJ, Lin JC, Cummins J, Boca S, Wood LD, Parsons DW, Jones S, Sjöblom T, Park BH, Parsons R, Willis J, Dawson D, Willson JK, Nikolskaya T, Nikolsky Y, ... ... Wang TL, et al. Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 105: 16224-9. PMID 18852474 DOI: 10.1073/Pnas.0808041105  0.781
2008 Davidson B, Shih IeM, Wang TL. Different clinical roles for p21-activated kinase-1 in primary and recurrent ovarian carcinoma. Human Pathology. 39: 1630-6. PMID 18656238 DOI: 10.1016/J.Humpath.2008.03.009  0.313
2008 Choi JH, Park JT, Davidson B, Morin PJ, Shih IeM, Wang TL. Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion. Cancer Research. 68: 5716-23. PMID 18632624 DOI: 10.1158/0008-5472.Can-08-0001  0.454
2008 Sheu JJ, Choi JH, Yildiz I, Tsai FJ, Shaul Y, Wang TL, Shih IeM. The roles of human sucrose nonfermenting protein 2 homologue in the tumor-promoting functions of Rsf-1. Cancer Research. 68: 4050-7. PMID 18519663 DOI: 10.1158/0008-5472.Can-07-3240  0.477
2008 Davidson B, Wang TL, Shih IeM, Berner A. Expression of the chromatin remodeling factor Rsf-1 is down-regulated in breast carcinoma effusions. Human Pathology. 39: 616-22. PMID 18289639 DOI: 10.1016/J.Humpath.2007.09.008  0.367
2007 Leary RJ, Cummins J, Wang TL, Velculescu VE. Digital karyotyping. Nature Protocols. 2: 1973-86. PMID 17703209 DOI: 10.1038/nprot.2007.276  0.697
2007 Nakayama K, Nakayama N, Jinawath N, Salani R, Kurman RJ, Shih IeM, Wang TL. Amplicon profiles in ovarian serous carcinomas. International Journal of Cancer. Journal International Du Cancer. 120: 2613-7. PMID 17351921 DOI: 10.1002/Ijc.22609  0.407
2007 Shih IeM, Salani R, Fiegl M, Wang TL, Soosaipillai A, Marth C, Müller-Holzner E, Gastl G, Zhang Z, Diamandis EP. Ovarian cancer specific kallikrein profile in effusions. Gynecologic Oncology. 105: 501-7. PMID 17303231 DOI: 10.1016/J.Ygyno.2007.01.018  0.394
2006 Nakayama K, Nakayama N, Davidson B, Sheu JJ, Jinawath N, Santillan A, Salani R, Bristow RE, Morin PJ, Kurman RJ, Wang TL, Shih IeM. A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival. Proceedings of the National Academy of Sciences of the United States of America. 103: 18739-44. PMID 17130457 DOI: 10.1073/Pnas.0604083103  0.43
2006 Wood LD, Calhoun ES, Silliman N, Ptak J, Szabo S, Powell SM, Riggins GJ, Wang TL, Yan H, Gazdar A, Kern SE, Pennacchio L, Kinzler KW, Vogelstein B, Velculescu VE. Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers Human Mutation.. 27: 1060-1061. PMID 16941478 DOI: 10.1002/Humu.9452  0.574
2006 Salani R, Chang CL, Cope L, Wang TL. Digital karyotyping: an update of its applications in cancer. Molecular Diagnosis & Therapy. 10: 231-7. PMID 16884326 DOI: 10.1007/BF03256461  0.301
2006 Park JT, Li M, Nakayama K, Mao TL, Davidson B, Zhang Z, Kurman RJ, Eberhart CG, Shih IeM, Wang TL. Notch3 gene amplification in ovarian cancer. Cancer Research. 66: 6312-8. PMID 16778208 DOI: 10.1158/0008-5472.Can-05-3610  0.35
2006 Nakayama K, Nakayama N, Kurman RJ, Cope L, Pohl G, Samuels Y, Velculescu VE, Wang TL, Shih IeM. Sequence mutations and amplification of PIK3CA and AKT2 genes in purified ovarian serous neoplasms. Cancer Biology & Therapy. 5: 779-85. PMID 16721043  0.358
2006 Yen MJ, Hsu CY, Mao TL, Wu TC, Roden R, Wang TL, Shih IeM. Diffuse mesothelin expression correlates with prolonged patient survival in ovarian serous carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 827-31. PMID 16467095 DOI: 10.1158/1078-0432.Ccr-05-1397  0.386
2005 Shih IeM, Sheu JJ, Santillan A, Nakayama K, Yen MJ, Bristow RE, Vang R, Parmigiani G, Kurman RJ, Trope CG, Davidson B, Wang TL. Amplification of a chromatin remodeling gene, Rsf-1/HBXAP, in ovarian carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 102: 14004-9. PMID 16172393 DOI: 10.1073/pnas.0504195102  0.339
2005 Köbel M, Pohl G, Schmitt WD, Hauptmann S, Wang TL, Shih IeM. Activation of mitogen-activated protein kinase is required for migration and invasion of placental site trophoblastic tumor. The American Journal of Pathology. 167: 879-85. PMID 16127165 DOI: 10.1016/S0002-9440(10)62059-7  0.345
2005 Parsons DW, Wang TL, Samuels Y, Bardelli A, Cummins JM, DeLong L, Silliman N, Ptak J, Szabo S, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Lengauer C, Velculescu VE. Colorectal cancer: mutations in a signalling pathway. Nature. 436: 792. PMID 16094359 DOI: 10.1038/436792A  0.755
2005 Chen YC, Davidson B, Cheng CC, Maitra A, Giuntoli RL, Hruban RH, Wang TL, Shih IeM. Identification and characterization of membralin, a novel tumor-associated gene, in ovarian carcinoma. Biochimica Et Biophysica Acta. 1730: 96-102. PMID 16084606 DOI: 10.1016/j.bbaexp.2005.06.008  0.356
2005 Pohl G, Ho CL, Kurman RJ, Bristow R, Wang TL, Shih IeM. Inactivation of the mitogen-activated protein kinase pathway as a potential target-based therapy in ovarian serous tumors with KRAS or BRAF mutations. Cancer Research. 65: 1994-2000. PMID 15753399 DOI: 10.1158/0008-5472.CAN-04-3625  0.323
2005 Chen YC, Pohl G, Wang TL, Morin PJ, Risberg B, Kristensen GB, Yu A, Davidson B, Shih IeM. Apolipoprotein E is required for cell proliferation and survival in ovarian cancer. Cancer Research. 65: 331-7. PMID 15665311  0.348
2005 Shih IM, Wang TL. Apply innovative technologies to explore cancer genome Current Opinion in Oncology. 17: 33-38. PMID 15608510 DOI: 10.1097/01.cco.0000147382.97085.e4  0.31
2004 Hsu CY, Bristow R, Cha MS, Wang BG, Ho CL, Kurman RJ, Wang TL, Shih IeM. Characterization of active mitogen-activated protein kinase in ovarian serous carcinomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 6432-6. PMID 15475429 DOI: 10.1158/1078-0432.Ccr-04-0893  0.388
2004 Wang Z, Shen D, Parsons DW, Bardelli A, Sager J, Szabo S, Ptak J, Silliman N, Peters BA, van der Heijden MS, Parmigiani G, Yan H, Wang TL, Riggins G, Powell SM, et al. Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science (New York, N.Y.). 304: 1164-6. PMID 15155950 DOI: 10.1126/Science.1096096  0.691
2004 Wang Z, Cummins JM, Shen D, Cahill DP, Jallepalli PV, Wang TL, Parsons DW, Traverso G, Awad M, Silliman N, Ptak J, Szabo S, Willson JK, Markowitz SD, Goldberg ML, et al. Three classes of genes mutated in colorectal cancers with chromosomal instability. Cancer Research. 64: 2998-3001. PMID 15126332 DOI: 10.1158/0008-5472.Can-04-0587  0.785
2004 Wang TL, Diaz LA, Romans K, Bardelli A, Saha S, Galizia G, Choti M, Donehower R, Parmigiani G, Shih IM, Iacobuzio-Donahue C, Kinzler KW, Vogelstein B, Lengauer C, Velculescu VE. Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients Proceedings of the National Academy of Sciences of the United States of America. 101: 3089-3094. PMID 14970324 DOI: 10.1073/Pnas.0308716101  0.464
2002 Wang TL, Maierhofer C, Speicher MR, Lengauer C, Vogelstein B, Kinzler KW, Velculescu VE. Digital karyotyping. Proceedings of the National Academy of Sciences of the United States of America. 99: 16156-61. PMID 12461184 DOI: 10.1073/Pnas.202610899  0.532
2002 Vardi N, Dhingra A, Zhang L, Lyubarsky A, Wang TL, Morigiwa K. Neurochemical organization of the first visual synapse. The Keio Journal of Medicine. 51: 154-64. PMID 12371647 DOI: 10.2302/Kjm.51.154  0.738
2002 Dhingra A, Jiang M, Wang TL, Lyubarsky A, Savchenko A, Bar-Yehuda T, Sterling P, Birnbaumer L, Vardi N. Light response of retinal ON bipolar cells requires a specific splice variant of Galpha(o). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4878-84. PMID 12077185  0.736
2002 Wang TL, Rago C, Silliman N, Ptak J, Markowitz S, Willson JK, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. Prevalence of somatic alterations in the colorectal cancer cell genome. Proceedings of the National Academy of Sciences of the United States of America. 99: 3076-80. PMID 11867767 DOI: 10.1073/Pnas.261714699  0.768
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