Year |
Citation |
Score |
2017 |
Kihara Y, Maeda R, Imaizumi A, Ichikawa T, Nemoto N, Ishihara T, Hirano N, Haruki M. Alkyne-Functionalized Cationic Polysiloxane Polymers Conjugated with Targeting Molecules by Click Reactions for DNA Delivery Journal of Nanoscience and Nanotechnology. 17: 5081-5089. DOI: 10.1166/Jnn.2017.13121 |
0.358 |
|
2015 |
Ishihara T, Hayashi E, Yamamoto S, Kobayashi C, Tamura Y, Sawazaki R, Tamura F, Tahara K, Kasahara T, Ishihara T, Takenaga M, Fukuda K, Mizushima T. Encapsulation of beraprost sodium in nanoparticles: analysis of sustained release properties, targeting abilities and pharmacological activities in animal models of pulmonary arterial hypertension. Journal of Controlled Release : Official Journal of the Controlled Release Society. 197: 97-104. PMID 25449809 DOI: 10.1016/J.Jconrel.2014.10.029 |
0.42 |
|
2014 |
Ishihara T, Kaneko K, Ishihara T, Mizushima T. Development of biodegradable nanoparticles for liver-specific ribavirin delivery. Journal of Pharmaceutical Sciences. 103: 4005-11. PMID 25335768 DOI: 10.1002/Jps.24219 |
0.457 |
|
2014 |
Kihara Y, Ichikawa T, Abe S, Nemoto N, Ishihara T, Hirano N, Haruki M. Synthesis of alkyne-functionalized amphiphilic polysiloxane polymers and formation of nanoemulsions conjugated with bioactive molecules by click reactions Polymer Journal. 46: 175-183. DOI: 10.1038/Pj.2013.86 |
0.305 |
|
2013 |
Ishihara T, Yamashita Y, Takasaki N, Yamamoto S, Hayashi E, Tahara K, Takenaga M, Yamakawa N, Ishihara T, Kasahara T, Mizushima T. Prostaglandin E1 -containing nanoparticles improve walking activity in an experimental rat model of intermittent claudication. The Journal of Pharmacy and Pharmacology. 65: 1187-94. PMID 23837586 DOI: 10.1111/Jphp.12080 |
0.419 |
|
2012 |
Ayano E, Karaki M, Ishihara T, Kanazawa H, Okano T. Poly (N-isopropylacrylamide)-PLA and PLA blend nanoparticles for temperature-controllable drug release and intracellular uptake. Colloids and Surfaces. B, Biointerfaces. 99: 67-73. PMID 22088756 DOI: 10.1016/J.Colsurfb.2011.10.003 |
0.367 |
|
2011 |
Sakai T, Ishihara T, Higaki M, Akiyama G, Tsuneoka H. Therapeutic effect of stealth-type polymeric nanoparticles with encapsulated betamethasone phosphate on experimental autoimmune uveoretinitis. Investigative Ophthalmology & Visual Science. 52: 1516-21. PMID 21178146 DOI: 10.1167/Iovs.10-5676 |
0.456 |
|
2011 |
Ishihara T, Kano A, Obara K, Saito M, Chen X, Park TG, Akaike T, Maruyama A. Nuclear localization and antisense effect of PNA internalized by ASGP-R-mediated endocytosis with protein/DNA conjugates. Journal of Controlled Release : Official Journal of the Controlled Release Society. 155: 34-9. PMID 20955741 DOI: 10.1016/J.Jconrel.2010.10.014 |
0.407 |
|
2010 |
Horie RT, Sakamoto T, Nakagawa T, Ishihara T, Higaki M, Ito J. Stealth-nanoparticle strategy for enhancing the efficacy of steroids in mice with noise-induced hearing loss. Nanomedicine (London, England). 5: 1331-40. PMID 21128717 DOI: 10.2217/Nnm.10.88 |
0.433 |
|
2010 |
Ishihara T, Maeda T, Sakamoto H, Takasaki N, Shigyo M, Ishida T, Kiwada H, Mizushima Y, Mizushima T. Evasion of the accelerated blood clearance phenomenon by coating of nanoparticles with various hydrophilic polymers. Biomacromolecules. 11: 2700-6. PMID 20795699 DOI: 10.1021/Bm100754E |
0.426 |
|
2010 |
Ishihara T, Mizushima T. Techniques for efficient entrapment of pharmaceuticals in biodegradable solid micro/nanoparticles. Expert Opinion On Drug Delivery. 7: 565-75. PMID 20230305 DOI: 10.1517/17425241003713486 |
0.322 |
|
2010 |
Ishihara T, Takahashi M, Higaki M, Mizushima Y, Mizushima T. Preparation and characterization of a nanoparticulate formulation composed of PEG-PLA and PLA as anti-inflammatory agents. International Journal of Pharmaceutics. 385: 170-5. PMID 19837147 DOI: 10.1016/J.Ijpharm.2009.10.025 |
0.439 |
|
2009 |
Matsuo Y, Ishihara T, Ishizaki J, Miyamoto K, Higaki M, Yamashita N. Effect of betamethasone phosphate loaded polymeric nanoparticles on a murine asthma model. Cellular Immunology. 260: 33-8. PMID 19716124 DOI: 10.1016/J.Cellimm.2009.07.004 |
0.312 |
|
2009 |
Ishihara T, Takeda M, Sakamoto H, Kimoto A, Kobayashi C, Takasaki N, Yuki K, Tanaka K, Takenaga M, Igarashi R, Maeda T, Yamakawa N, Okamoto Y, Otsuka M, Ishida T, et al. Accelerated blood clearance phenomenon upon repeated injection of PEG-modified PLA-nanoparticles. Pharmaceutical Research. 26: 2270-9. PMID 19633820 DOI: 10.1007/S11095-009-9943-X |
0.429 |
|
2009 |
Ishihara T, Goto M, Kodera K, Kanazawa H, Murakami Y, Mizushima Y, Higaki M. Intracellular delivery of siRNA by cell-penetrating peptides modified with cationic oligopeptides. Drug Delivery. 16: 153-9. PMID 19514975 DOI: 10.1080/10717540902722774 |
0.329 |
|
2009 |
Ishihara T, Kubota T, Choi T, Takahashi M, Ayano E, Kanazawa H, Higaki M. Polymeric nanoparticles encapsulating betamethasone phosphate with different release profiles and stealthiness. International Journal of Pharmaceutics. 375: 148-54. PMID 19481700 DOI: 10.1016/J.Ijpharm.2009.04.001 |
0.468 |
|
2009 |
Takeda M, Maeda T, Ishihara T, Sakamoto H, Yuki K, Takasaki N, Nishimura F, Yamashita T, Tanaka K, Takenaga M, Igarashi R, Higaki M, Yamakawa N, Okamoto Y, Ogawa H, et al. Synthesis of prostaglandin E(1) phosphate derivatives and their encapsulation in biodegradable nanoparticles. Pharmaceutical Research. 26: 1792-800. PMID 19415470 DOI: 10.1007/S11095-009-9891-5 |
0.378 |
|
2009 |
Ishihara T, Kubota T, Choi T, Higaki M. Treatment of experimental arthritis with stealth-type polymeric nanoparticles encapsulating betamethasone phosphate. The Journal of Pharmacology and Experimental Therapeutics. 329: 412-7. PMID 19244548 DOI: 10.1124/Jpet.108.150276 |
0.417 |
|
2009 |
Ishihara T, Goto M, Kanazawa H, Higaki M, Mizushima Y. Efficient entrapment of poorly water-soluble pharmaceuticals in hybrid nanoparticles. Journal of Pharmaceutical Sciences. 98: 2357-63. PMID 18979534 DOI: 10.1002/Jps.21605 |
0.44 |
|
2009 |
Ishihara T, Takahashi M, Higaki M, Mizushima Y. Efficient encapsulation of a water-soluble corticosteroid in biodegradable nanoparticles. International Journal of Pharmaceutics. 365: 200-5. PMID 18804157 DOI: 10.1016/J.Ijpharm.2008.08.030 |
0.46 |
|
2008 |
Ishihara T, Takahashi M, Higaki M, Takenaga M, Mizushima T, Mizushima Y. Prolonging the in vivo residence time of prostaglandin E(1) with biodegradable nanoparticles. Pharmaceutical Research. 25: 1686-95. PMID 18293063 DOI: 10.1007/S11095-008-9549-8 |
0.404 |
|
2006 |
Higaki M, Kameyama M, Udagawa M, Ueno Y, Yamaguchi Y, Igarashi R, Ishihara T, Mizushima Y. Transdermal delivery of CaCO3-nanoparticles containing insulin. Diabetes Technology & Therapeutics. 8: 369-74. PMID 16800758 DOI: 10.1089/Dia.2006.8.369 |
0.358 |
|
2006 |
Sakai T, Kohno H, Ishihara T, Higaki M, Saito S, Matsushima M, Mizushima Y, Kitahara K. Treatment of experimental autoimmune uveoretinitis with poly(lactic acid) nanoparticles encapsulating betamethasone phosphate. Experimental Eye Research. 82: 657-63. PMID 16360654 DOI: 10.1016/J.Exer.2005.09.003 |
0.371 |
|
2005 |
Tamura T, Kita T, Nakagawa T, Endo T, Kim TS, Ishihara T, Mizushima Y, Higaki M, Ito J. Drug delivery to the cochlea using PLGA nanoparticles. The Laryngoscope. 115: 2000-5. PMID 16319613 DOI: 10.1097/01.Mlg.0000180174.81036.5A |
0.435 |
|
2005 |
Ishihara T, Izumo N, Higaki M, Shimada E, Hagi T, Mine L, Ogawa Y, Mizushima Y. Role of zinc in formulation of PLGA/PLA nanoparticles encapsulating betamethasone phosphate and its release profile. Journal of Controlled Release : Official Journal of the Controlled Release Society. 105: 68-76. PMID 15955367 DOI: 10.1016/J.Jconrel.2005.02.026 |
0.446 |
|
2005 |
Higaki M, Ishihara T, Izumo N, Takatsu M, Mizushima Y. Treatment of experimental arthritis with poly(D, L-lactic/glycolic acid) nanoparticles encapsulating betamethasone sodium phosphate. Annals of the Rheumatic Diseases. 64: 1132-1136. PMID 15695536 DOI: 10.1136/Ard.2004.030759 |
0.402 |
|
2004 |
Goto M, Ishihara T, Higaki M, Mizushima Y, Kanazawa H. Preparation of nanoparticles covered with inorganic compound as a drug carrier. Journal of Life Support Engineering. 16: 183-184. DOI: 10.5136/Lifesupport.16.Supplement_183 |
0.383 |
|
2001 |
Kim WJ, Ishihara T, Akaike T, Maruyama A. Comb-type cationic copolymer expedites DNA strand exchange while stabilizing DNA duplex Chemistry: a European Journal. 7: 176-180. PMID 11205009 DOI: 10.1002/1521-3765(20010105)7:1<176::Aid-Chem176>3.0.Co;2-M |
0.359 |
|
2001 |
Cho CS, Kobayashi A, Takei R, Ishihara T, Maruyama A, Akaike T. Receptor-mediated cell modulator delivery to hepatocyte using nanoparticles coated with carbohydrate-carrying polymers. Biomaterials. 22: 45-51. PMID 11085382 DOI: 10.1016/S0142-9612(00)00143-5 |
0.417 |
|
2000 |
Zhang X, Ishihara T, Corey DR. Strand invasion by mixed base PNAs and a PNA-peptide chimera. Nucleic Acids Research. 28: 3332-8. PMID 10954602 DOI: 10.1093/Nar/28.17.3332 |
0.555 |
|
2000 |
Ishihara T, Akaike T, Maruyama A. Biomaterials for gene delivery Drug Delivery System. 15: 106-112. DOI: 10.2745/Dds.15.106 |
0.396 |
|
1999 |
Ishihara T, Corey DR. Strand invasion by DNA-peptide conjugates and peptide nucleic acids. Nucleic Acids Symposium Series. 141-2. PMID 10780419 |
0.509 |
|
1999 |
Park JU, Ishihara T, Kano A, Akaike T, Maruyama A. Preparation of dendritic graft copolymer consisting of poly-(L-lysine) and arabinogalactan as a hepatocyte specific DNA carrier. Preparative Biochemistry & Biotechnology. 29: 353-70. PMID 10548252 DOI: 10.1080/10826069908544934 |
0.363 |
|
1999 |
Maruyama A, Ferdous A, Ishihara T, Asayama S, Park JU, Nogawa M, Watanabe H, Takei Y, Akaike T. Comb-type copolymers for controlled DNA delivery. Nucleosides & Nucleotides. 18: 1681-2. PMID 10474245 DOI: 10.1080/07328319908044821 |
0.424 |
|
1999 |
Ishihara T, Corey DR. Rules for strand invasion by chemically modified oligonucleotides Journal of the American Chemical Society. 121: 2012-2020. DOI: 10.1021/Ja983834E |
0.554 |
|
1999 |
Maruyama A, Ishihara T, Kim JS, Kim SW, Akaike T. Design of multi-functional nanoparticles as a DNA carrier Colloids and Surfaces a: Physicochemical and Engineering Aspects. 153: 439-443. DOI: 10.1016/S0927-7757(98)00534-2 |
0.443 |
|
1998 |
Maruyama A, Watanabe H, Ferdous A, Katoh M, Ishihara T, Akaike T. Characterization of interpolyelectrolyte complexes between double-stranded DNA and polylysine comb-type copolymers having hydrophilic side chains Bioconjugate Chemistry. 9: 292-299. PMID 9548547 DOI: 10.1021/Bc9701510 |
0.347 |
|
1997 |
Maruyama A, Ishihara T, Kim JS, Kim SW, Akaike T. Nanoparticle DNA Carrier with Poly(l-lysine) Grafted Polysaccharide Copolymer and Poly(d,l-lactic acid) Bioconjugate Chemistry. 8: 735-742. PMID 9327139 DOI: 10.1021/Bc9701048 |
0.434 |
|
1997 |
Cho CS, Jeong YI, Ishihara T, Takei R, Park JU, Park KH, Maruyama A, Akaike T. Simple preparation of nanoparticles coated with carbohydrate-carrying polymers. Biomaterials. 18: 323-6. PMID 9068894 DOI: 10.1016/S0142-9612(96)00138-X |
0.416 |
|
1997 |
Maruyama A, Katoh M, Ishihara T, Akaike T. Comb-type polycations effectively stabilize DNA triplex. Bioconjugate Chemistry. 8: 3-6. PMID 9026028 DOI: 10.1021/Bc960071G |
0.365 |
|
1994 |
Maruyama A, Ishihara T, Adachi N, Akaike T. Preparation of nanoparticles bearing high density carbohydrate chains using carbohydrate-carrying polymers as emulsifier Biomaterials. 15: 1035-1042. PMID 7888573 DOI: 10.1016/0142-9612(94)90088-4 |
0.39 |
|
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