Year |
Citation |
Score |
2022 |
Nguyen TTL, Gao H, Liu D, Philips TJ, Ye Z, Lee JH, Shi GX, Copenhaver K, Zhang L, Wei L, Yu J, Zhang H, Barath A, Luong M, Zhang C, ... ... Wang L, et al. Glucocorticoids unmask silent non-coding genetic risk variants for common diseases. Nucleic Acids Research. PMID 36399508 DOI: 10.1093/nar/gkac1045 |
0.308 |
|
2022 |
Thompson KJ, Leon-Ferre RA, Sinnwell JP, Zahrieh DM, Suman VJ, Metzger FO, Asad S, Stover DG, Carey L, Sikov WM, Ingle JN, Liu MC, Carter JM, Klee EW, Weinshilboum RM, ... ... Wang L, et al. Luminal androgen receptor breast cancer subtype and investigation of the microenvironment and neoadjuvant chemotherapy response. Nar Cancer. 4: zcac018. PMID 35734391 DOI: 10.1093/narcan/zcac018 |
0.312 |
|
2022 |
Fasching PA, Liu D, Scully S, Ingle JN, Lyra PC, Rack B, Hein A, Ekici AB, Reis A, Schneeweiss A, Tesch H, Fehm TN, Heinrich G, Beckmann MW, Ruebner M, ... ... Wang L, et al. Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Breast Cancer Patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 35653140 DOI: 10.1158/1078-0432.CCR-20-4774 |
0.308 |
|
2021 |
Zhuang Y, Grainger JM, Vedell PT, Yu J, Moyer AM, Gao H, Fan XY, Qin S, Liu D, Kalari KR, Goetz MP, Boughey JC, Weinshilboum RM, Wang L. Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX). Npj Breast Cancer. 7: 79. PMID 34145270 DOI: 10.1038/s41523-021-00285-x |
0.301 |
|
2021 |
Cairns J, Kalari KR, Ingle JN, Shepherd LE, Ellis MJ, Goss PE, Barman P, Carlson EE, Goodnature B, Goetz MP, Weinshilboum RM, Gao H, Wang L. Interaction between SNP Genotype and Efficacy of Anastrozole and Exemestane in Early Stage Breast Cancer. Clinical Pharmacology and Therapeutics. PMID 34048027 DOI: 10.1002/cpt.2311 |
0.327 |
|
2020 |
Wen S, He Y, Wang L, Zhang J, Quan C, Niu Y, Huang H. Aberrant activation of super enhancer and choline metabolism drive antiandrogen therapy resistance in prostate cancer. Oncogene. PMID 32917955 DOI: 10.1038/S41388-020-01456-Z |
0.349 |
|
2020 |
Cairns J, Ingle JN, Dudenkov TTM, Kalari KR, Carlson EE, Na J, Buzdar AU, Robson ME, Ellis MJ, Goss PE, Shepherd LE, Goodnature B, Goetz MP, Weinshilboum RM, Li H, ... ... Wang L, et al. Pharmacogenomics of aromatase inhibitors in postmenopausal breast cancer and additional mechanisms of anastrozole action. Jci Insight. PMID 32701512 DOI: 10.1172/Jci.Insight.137571 |
0.447 |
|
2020 |
Ingle JN, Kalari KR, Barman P, Shepherd LE, Ellis MJ, Goss PE, Buzdar AU, Robson ME, Cairns J, Carlson EE, Eyman Casey A, Hoskin TL, Goodnature BA, Haddad TC, Goetz MP, ... ... Wang L, et al. Single-nucleotide polymorphism biomarkers of adjuvant anastrozole-induced estrogen suppression in early breast cancer. Pharmacogenetics and Genomics. PMID 32649577 DOI: 10.1097/Fpc.0000000000000415 |
0.366 |
|
2020 |
Zayas J, Qin S, Yu J, Ingle JN, Wang L. Functional genomics based on germline genome-wide association studies of endocrine therapy for breast cancer. Pharmacogenomics. PMID 32539536 DOI: 10.2217/Pgs-2019-0191 |
0.449 |
|
2020 |
John A, Qin B, Kalari KR, Wang L, Yu J. Patient-specific multi-omics models and the application in personalized combination therapy. Future Oncology (London, England). PMID 32462937 DOI: 10.2217/Fon-2020-0119 |
0.314 |
|
2020 |
Du M, Tian Y, Tan W, Wang L, Wang L, Kilari D, Huang CC, Wang L, Kohli M. Plasma cell-free DNA-based predictors of response to abiraterone acetate/prednisone and prognostic factors in metastatic castration-resistant prostate cancer. Prostate Cancer and Prostatic Diseases. PMID 32203070 DOI: 10.1038/S41391-020-0224-4 |
0.351 |
|
2020 |
Ingle JN, Cairns J, Suman VJ, Shepherd LE, Fasching PA, Hoskin TL, Singh RJ, Desta Z, Kalari KR, Ellis MJ, Goss PE, Chen BE, Volz B, Barman P, Carlson EE, ... ... Wang L, et al. Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor α. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32098767 DOI: 10.1158/1078-0432.Ccr-19-3091 |
0.35 |
|
2020 |
Zhang L, Sarangi V, Moon I, Yu J, Liu D, Devarajan S, Reid JM, Kalari KR, Wang L, Weinshilboum R. CYP2C9 and CYP2C19: Deep Mutational Scanning and Functional Characterization of Genomic Missense Variants. Clinical and Translational Science. PMID 32004414 DOI: 10.1111/Cts.12758 |
0.351 |
|
2020 |
Leon-Ferre RA, McGrath K, Carter JM, Kalari KR, Suman VJ, Weinshilboum R, Wang L, Knutson KL, Ansell SM, Boughey JC, Villasboas JC, Goetz MP. Abstract P5-04-09: Deep phenotyping using CyTOF identifies peripheral blood immune signatures associated with clinical outcomes and molecular subtypes in patients with early-stage triple negative breast cancer (TNBC) Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P5-04-09 |
0.349 |
|
2020 |
Grainger JM, Yu J, Kalari KR, Vedell P, Thompson K, Goetz MP, Suman VJ, Boughey JC, Wang L. Abstract 1928: Study of copy number amplification and chemo-response in triple negative breast cancer Cancer Research. 80: 1928-1928. DOI: 10.1158/1538-7445.Am2020-1928 |
0.441 |
|
2020 |
Myasoedova E, Athreya A, Crowson CS, Weinshilboum R, Wang L, Matteson E. Fri0046 Pharmacogenomics-Driven Individualized Prediction Of Treatment Response To Methotrexate In Patients With Rheumatoid Arthritis: A Machine Learning Approach Annals of the Rheumatic Diseases. 79: 598-598. DOI: 10.1136/Annrheumdis-2020-Eular.4993 |
0.322 |
|
2019 |
Yu J, Zayas J, Qin B, Wang L. Targeting DNA methylation for treating triple-negative breast cancer. Pharmacogenomics. 20: 1151-1157. PMID 31755366 DOI: 10.2217/Pgs-2019-0078 |
0.374 |
|
2019 |
Qin S, Eugene AR, Liu D, Zhang L, Neavin D, Biernacka JM, Yu J, Weinshilboum RM, Wang L. Dual roles for the TSPYL family in mediating serotonin transport and the metabolism of selective serotonin reuptake inhibitors in MDD patients. Clinical Pharmacology and Therapeutics. PMID 31628858 DOI: 10.1002/Cpt.1692 |
0.351 |
|
2019 |
Shee K, Wells JD, Ung M, Hampsch RA, Traphagen NA, Yang W, Liu SC, Zeldenrust MA, Wang L, Kalari KR, Yu J, Boughey JC, Demidenko E, Kettenbach AN, Cheng C, et al. A transcriptionally-definable subgroup of triple-negative breast and ovarian cancer samples shows sensitivity to HSP90 inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31558472 DOI: 10.1158/1078-0432.Ccr-18-2213 |
0.381 |
|
2019 |
Ruddy KJ, Schaid DJ, Partridge AH, Larson NB, Batzler A, Häberle L, Dittrich R, Widschwendter P, Fink V, Bauer E, Schwitulla J, Rübner M, Ekici AB, Aivazova-Fuchs V, Stewart EA, ... ... Wang L, et al. Genetic predictors of chemotherapy-related amenorrhea in women with breast cancer. Fertility and Sterility. PMID 31371054 DOI: 10.1016/J.Fertnstert.2019.05.018 |
0.353 |
|
2019 |
Neavin DR, Lee JH, Liu D, Ye Z, Li H, Wang L, Ordog T, Weinshilboum RM. Single Nucleotide Polymorphisms at a Distance from Aryl Hydrocarbon Receptor Binding Sites Influence AHR Ligand-Dependent Gene Expression. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31292129 DOI: 10.1124/Dmd.119.087312 |
0.407 |
|
2019 |
Ingle JN, Kalari KR, Momozawa Y, Kubo M, Furukawa Y, Shepherd LE, Ellis MJ, Goss PE, Barman P, Carlson EE, Sinnwell JP, Tang X, Goetz MP, Chen BE, Cairns J, ... ... Wang L, et al. Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer. Pharmacogenetics and Genomics. PMID 31211741 DOI: 10.1097/Fpc.0000000000000382 |
0.393 |
|
2019 |
Pereira NL, Rihal CS, So DYF, Rosenberg Y, Lennon RJ, Mathew V, Goodman SG, Weinshilboum RM, Wang L, Baudhuin LM, Lerman A, Hasan A, Iturriaga E, Fu YP, Geller N, et al. Clopidogrel Pharmacogenetics. Circulation. Cardiovascular Interventions. 12: e007811. PMID 30998396 DOI: 10.1161/Circinterventions.119.007811 |
0.316 |
|
2019 |
Cairns J, Ingle JN, Kalari KR, Shepherd LE, Kubo M, Goetz MP, Weinshilboum RM, Wang L. The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1. Breast Cancer Research : Bcr. 21: 47. PMID 30944027 DOI: 10.1186/S13058-019-1130-3 |
0.402 |
|
2019 |
Wang G, Qin S, Zayas J, Ingle JN, Liu M, Weinshilboum RM, Shen K, Wang L. 4-Hydroxytamoxifen enhances sensitivity of estrogen receptor α-positive breast cancer to docetaxel in an estrogen and ZNF423 SNP-dependent fashion. Breast Cancer Research and Treatment. PMID 30937657 DOI: 10.1007/S10549-019-05194-Z |
0.442 |
|
2019 |
Liu D, Qin S, Ray B, Kalari KR, Wang L, Weinshilboum RM. Correction: Single nucleotide polymorphisms (snps) distant from xenobiotic response elements can modulate aryl hydrocarbon receptor function: snp-dependent cyp1a1 induction (Drug Metabolism and Disposition (2018) 46:9 (1372-1381) DOI: 10.1124/dmd.118.082164) Drug Metabolism and Disposition. PMID 30760463 DOI: 10.1124/Dmd.117.082164Err |
0.347 |
|
2019 |
Devarajan S, Moon I, Ho M, Larson NB, Neavin DR, Moyer AM, Black JL, Bielinski SJ, Scherer SE, Wang L, Weinshilboum RM, Reid JM. Pharmacogenomic Next-Generation DNA Sequencing: Lessons from the Identification and Functional Characterization of Variants of Unknown Significance in CYP2C9 and CYP2C19. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 30745309 DOI: 10.1124/Dmd.118.084269 |
0.337 |
|
2019 |
Zhuang Y, Ly RC, Frazier CV, Yu J, Qin S, Fan XY, Goetz MP, Boughey JC, Weinshilboum R, Wang L. The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer. Cancer & Metabolism. 7: 1. PMID 30697423 DOI: 10.1186/S40170-018-0193-4 |
0.394 |
|
2019 |
Dudenkov TM, Liu D, Cairns J, Devarajan S, Zhuang Y, Ingle JN, Buzdar AU, Robson ME, Kubo M, Batzler A, Barman P, Jenkins GD, Carlson EE, Goetz MP, Northfelt DW, ... ... Wang L, et al. Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome-Wide Association Study: Functional Epistatic Interaction between SLC38A7 and ALPPL2. Clinical Pharmacology and Therapeutics. PMID 30648747 DOI: 10.1002/Cpt.1359 |
0.43 |
|
2019 |
Giridhar K, Sosa C, Sicotte H, Wang L, Wang L, Sinnwell JP, Tan W, Costello BA, Quevedo F, Pitot HC, Bryce AH, Jimenez RE, Weinshilboum RM, Dehm S, Kalari KR, et al. Evolution of androgen receptor variant (ARV) profiles in serial metastatic solid and liquid biopsies in metastatic castrate resistant prostate cancer (mCRPC) treated with abiraterone acetate/ prednisone (AA/P). Journal of Clinical Oncology. 37: e16559-e16559. DOI: 10.1200/Jco.2019.37.15_Suppl.E16559 |
0.304 |
|
2019 |
Wang G, Qin S, Zayas J, Ingle JN, Liu M, Weinshilboum R, Shen K, Wang L. Abstract 2940: 4-Hydroxytamoxifen enhances sensitivity of estrogen receptor α-positive breast cancer to docetaxel in an estrogen andZNF423SNP-dependent fashion Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2940 |
0.32 |
|
2019 |
Yu J, Qin B, Boughey J, Goetz M, Wang L. Abstract 2980: The role of USP7 and USP7 inhibitor in HER2+ breast cancer treatment Cancer Research. 79: 2980-2980. DOI: 10.1158/1538-7445.Am2019-2980 |
0.415 |
|
2018 |
Wu X, Li Y, Liu X, Chen C, Harrington SM, Cao S, Xie T, Orzechowski A, Pham T, Mansfield AS, Yan Y, Kwon ED, Wang L, Ling K, Dong H. Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy. Heliyon. 4: e01039. PMID 30603685 DOI: 10.1016/J.Heliyon.2018.E01039 |
0.337 |
|
2018 |
Tu X, Kahila MM, Zhou Q, Yu J, Kalari KR, Wang L, Harmsen WS, Yuan J, Boughey JC, Goetz MP, Sarkaria JN, Lou Z, Mutter RW. ATR inhibition is a promising radiosensitizing strategy for triple negative breast cancer. Molecular Cancer Therapeutics. PMID 30166399 DOI: 10.1158/1535-7163.MCT-18-0470 |
0.32 |
|
2018 |
Baheti S, Tang X, O'Brien DR, Chia N, Roberts LR, Nelson H, Boughey JC, Wang L, Goetz MP, Kocher JA, Kalari KR. HGT-ID: an efficient and sensitive workflow to detect human-viral insertion sites using next-generation sequencing data. Bmc Bioinformatics. 19: 271. PMID 30016933 DOI: 10.1186/S12859-018-2260-9 |
0.319 |
|
2018 |
Athreya AP, Gaglio AJ, Cairns J, Kalari KR, Weinshilboum RM, Wang L, Kalbarczyk ZT, Iyer RK. Machine Learning helps Identify New Drug Mechanisms in Triple-Negative Breast Cancer. Ieee Transactions On Nanobioscience. PMID 29994716 DOI: 10.1109/Tnb.2018.2851997 |
0.402 |
|
2018 |
Kohli M, Li J, Du M, Hillman DW, Dehm SM, Tan W, Carlson R, Campion MB, Wang L, Wang L, Zhang H, Zhang P, Kilari D, Huang CC, Wang L. Prognostic association of plasma cell-free DNA-based androgen receptor amplification and circulating tumor cells in pre-chemotherapy metastatic castration-resistant prostate cancer patients. Prostate Cancer and Prostatic Diseases. PMID 29858592 DOI: 10.1038/S41391-018-0043-Z |
0.341 |
|
2018 |
Ingle JN, Kalari KR, Wickerham DL, von Minckwitz G, Fasching PA, Furukawa Y, Mushiroda T, Goetz MP, Barman P, Carlson EE, Rastogi P, Costantino JP, Cairns J, Paik S, Bear HD, ... ... Wang L, et al. Germline genome-wide association studies in women receiving neoadjuvant chemotherapy with or without bevacizumab. Pharmacogenetics and Genomics. 28: 147-152. PMID 29768301 DOI: 10.1097/FPC.0000000000000337 |
0.312 |
|
2018 |
Yu J, Qin B, Moyer AM, Nowsheen S, Liu T, Qin S, Zhuang Y, Liu D, Lu SW, Kalari KR, Visscher DW, Copland JA, McLaughlin SA, Moreno-Aspitia A, Northfelt DW, ... ... Wang L, et al. DNA methyltransferase expression in triple-negative breast cancer predicts sensitivity to decitabine. The Journal of Clinical Investigation. PMID 29708513 DOI: 10.1172/Jci97924 |
0.402 |
|
2018 |
Bidadi B, Liu D, Kalari KR, Rubner M, Hein A, Beckmann MW, Rack B, Janni W, Fasching PA, Weinshilboum RM, Wang L. Pathway-Based Analysis of Genome-Wide Association Data Identified SNPs inas Biomarker for Chemotherapy- Induced Neutropenia in Breast Cancer Patients. Frontiers in Pharmacology. 9: 158. PMID 29593529 DOI: 10.3389/Fphar.2018.00158 |
0.496 |
|
2018 |
He Y, Lu J, Ye Z, Hao S, Wang L, Kohli M, Tindall DJ, Li B, Zhu R, Wang L, Huang H. Androgen receptor splice variants bind to constitutively open chromatin and promote abiraterone-resistant growth of prostate cancer. Nucleic Acids Research. PMID 29309643 DOI: 10.1093/Nar/Gkx1306 |
0.381 |
|
2018 |
Cairns J, Ingle J, Shepherd L, Kubo M, Goetz M, Weinshilboum R, Kalari K, Wang L. Abstract P5-07-01: LncRNA MIR2052HG regulates ERα level and endocrine resistance through LMTK3 by recruiting early growth response protein 1 Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P5-07-01 |
0.328 |
|
2018 |
Mutter RW, Kahila MM, Tu X, Zhou Q, Yu J, Kalari KR, Wang L, Boughey JC, Goetz MP, Sarkaria JN, Lou Z. Abstract 840: ATR inhibition is a promising radiosensitizing strategy for chemotherapy-resistant triple negative breast cancer (TNBC) Cancer Research. 78: 840-840. DOI: 10.1158/1538-7445.Am2018-840 |
0.426 |
|
2017 |
Yu J, Qin B, Moyer AM, Sinnwell JP, Thompson KJ, Copland JA, Marlow LA, Miller JL, Yin P, Gao B, Minter-Dykhouse K, Tang X, McLaughlin SA, Moreno-Aspitia A, Schweitzer A, ... ... Wang L, et al. Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer study. Breast Cancer Research : Bcr. 19: 130. PMID 29212525 DOI: 10.1186/S13058-017-0920-8 |
0.396 |
|
2017 |
Fasching PA, Häberle L, Rack B, Li L, Hein A, Ekici AB, Reis A, Lux MP, Cunningham JM, Ruebner M, Jenkins G, Fridley B, Schneeweiss A, Tesch H, Lichtenegger W, ... ... Wang L, et al. Clinical validation of genetic variants associated with in vitro chemotherapy-related lymphoblastoid cell toxicity. Oncotarget. 8: 78133-78143. PMID 29100455 DOI: 10.18632/Oncotarget.17726 |
0.43 |
|
2017 |
Qin S, Liu D, Kohli M, Wang L, Vedell PT, Hillman DW, Niu N, Yu J, Weinshilboum RM, Wang L. TSPYL Family Regulates CYP17A1 and CYP3A4 Expression: Potential Mechanism Contributing to Abiraterone Response in Metastatic Castration-Resistant Prostate Cancer. Clinical Pharmacology and Therapeutics. PMID 29027195 DOI: 10.1002/Cpt.907 |
0.416 |
|
2017 |
Cairns J, Ingle JN, Wickerham LD, Weinshilboum R, Liu M, Wang L. SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1. Plos Genetics. 13: e1007031. PMID 28968398 DOI: 10.1371/journal.pgen.1007031 |
0.377 |
|
2017 |
Liu D, Ho MF, Schaid DJ, Scherer SE, Kalari K, Liu M, Biernacka J, Yee V, Evans J, Carlson E, Goetz MP, Kubo M, Wickerham DL, Wang L, Ingle JN, et al. Breast cancer chemoprevention pharmacogenomics: Deep sequencing and functional genomics of the ZNF423 and CTSO genes. Npj Breast Cancer. 3: 30. PMID 28856246 DOI: 10.1038/s41523-017-0036-4 |
0.346 |
|
2017 |
Qin S, Ingle JN, Liu M, Yu J, Wickerham DL, Kubo M, Weinshilboum RM, Wang L. Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion. Breast Cancer Research : Bcr. 19: 95. PMID 28821270 DOI: 10.1186/s13058-017-0890-x |
0.323 |
|
2017 |
Dai X, Gan W, Li X, Wang S, Zhang W, Huang L, Liu S, Zhong Q, Guo J, Zhang J, Chen T, Shimizu K, Beca F, Blattner M, Vasudevan D, ... ... Wang L, et al. Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. Nature Medicine. PMID 28805820 DOI: 10.1038/Nm.4378 |
0.357 |
|
2017 |
Ho MF, Ingle JN, Bongartz T, Kalari KR, Goss PE, Shepherd LE, Mushiroda T, Kubo M, Wang L, Weinshilboum RM. TCL1A SNPs and estrogen-mediated toll-like receptor-MYD88-dependent NF-κB activation: SNP and SERM-dependent modification of inflammation and immune response. Molecular Pharmacology. PMID 28615284 DOI: 10.1124/Mol.117.108340 |
0.405 |
|
2017 |
Fasching PA, Häberle L, Rack B, Li L, Hein A, Ekici AB, Reis A, Lux MP, Cunningham JM, Ruebner M, Jenkins G, Fridley B, Schneeweiss A, Tesch H, Lichtenegger W, ... ... Wang L, et al. Clinical validation of genetic variants associated with in vitro chemotherapy-related lymphoblastoid cell toxicity. Oncotarget. PMID 28537877 DOI: 10.18632/oncotarget.17726 |
0.321 |
|
2017 |
Kohli M, Ho Y, Hillman DW, Van Etten JL, Henzler C, Yang R, Sperger JM, Li Y, Tseng E, Hon T, Clark T, Tan W, Carlson RE, Wang L, Sicotte H, ... ... Wang L, et al. Androgen receptor variant AR-V9 is co-expressed with AR-V7 in prostate cancer metastases and predicts abiraterone resistance. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28473535 DOI: 10.1158/1078-0432.Ccr-17-0017 |
0.323 |
|
2017 |
Dudenkov TM, Ingle JN, Buzdar AU, Robson ME, Kubo M, Ibrahim-Zada I, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Barman P, Goetz MP, Northfelt DW, Moreno-Aspita A, Williard CV, ... ... Wang L, et al. SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway. Breast Cancer Research and Treatment. PMID 28429243 DOI: 10.1007/S10549-017-4243-3 |
0.378 |
|
2017 |
Athreya AP, Kalari KR, Cairns J, Gaglio AJ, Wills QF, Niu N, Weinshilboum R, Iyer RK, Wang L. Model-based unsupervised learning informs metformin-induced cell-migration inhibition through an AMPK-independent mechanism in breast cancer. Oncotarget. 27199-27215. PMID 28423712 DOI: 10.18632/Oncotarget.16109 |
0.407 |
|
2017 |
Goetz MP, Kalari KR, Suman VJ, Moyer AM, Yu J, Visscher DW, Dockter TJ, Vedell PT, Sinnwell JP, Tang X, Thompson KJ, McLaughlin SA, Moreno-Aspitia A, Copland JA, Northfelt DW, ... ... Wang L, et al. Tumor Sequencing and Patient-Derived Xenografts in the Neoadjuvant Treatment of Breast Cancer. Journal of the National Cancer Institute. 109. PMID 28376176 DOI: 10.1093/Jnci/Djw306 |
0.387 |
|
2017 |
Liu T, Yu J, Deng M, Yin Y, Zhang H, Luo K, Qin B, Li Y, Wu C, Ren T, Han Y, Yin P, Kim J, Lee S, Lin J, ... ... Wang L, et al. CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1. Nature Communications. 8: 13923. PMID 28067227 DOI: 10.1038/Ncomms13923 |
0.367 |
|
2017 |
Kohli M, Wang L, Dehm S, Hillman DW, Sicotte H, Gormley M, Bhargava V, Ricci DS, Li W, Tan W, Costello BA, Pitot HC, Dronca RS, Ho TH, Bryce AH, ... ... Wang L, et al. Association of Wnt pathway activation with prechemotherapy abiraterone acetate resistance in metastatic castration-resistant prostate cancer (mCRPC) by genome-wide analysis of metastases. Journal of Clinical Oncology. 35: 175-175. DOI: 10.1200/Jco.2017.35.6_Suppl.175 |
0.358 |
|
2017 |
Kohli M, Li J, Du M, Hillman DW, Tan W, Carlson R, Wang L, Wang L, Liu MC, Zhang H, Zhang P, Wang L. Circulating tumor cells (CTCs) and plasma cell free DNA (cfDNA) androgen receptor amplification (ARamp)-based prognosis in metastatic castration-resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 35: 152-152. DOI: 10.1200/Jco.2017.35.6_Suppl.152 |
0.313 |
|
2017 |
Kohli M, Wang L, Dehm S, Hillman DW, Sicotte H, Gormley M, Bhargava V, Li W, Tan W, Pitot HC, Ho TH, Costello BA, Bryce AH, Zhenqing Y, Vedell PT, ... ... Wang L, et al. Genome-wide analysis of metastases to reveal association of pathway activation with abiraterone acetate/prednisone (AA/P) primary resistance and cell cycle proliferation pathway activation with response duration in metastatic castrate resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 35: 5053-5053. DOI: 10.1200/Jco.2017.35.15_Suppl.5053 |
0.368 |
|
2017 |
Ku KP, Lang JM, Sperger J, Dehm S, Kohli M, Wang L, Wang L, Tagawa ST, Scher HI. Trop-2 expression on treatment resistant cancer cells in castrate-resistant prostate cancer (CRPC) as a predictive biomarker for targeted therapy. Journal of Clinical Oncology. 35: 5045-5045. DOI: 10.1200/Jco.2017.35.15_Suppl.5045 |
0.38 |
|
2017 |
Kohli M, Ho Y, Hillman DW, Etten JLV, Henzler C, Yang R, Li Y, Tseng E, Hon T, Clark TA, Wang L, Silverstein K, Wang L, Dehm SM. Abstract 425: SMRT® Sequencing of full-length androgen receptor isoforms in prostate cancer reveals previously hidden drug resistant variants Cancer Research. 77: 425-425. DOI: 10.1158/1538-7445.Am2017-425 |
0.326 |
|
2017 |
Huang C, Du M, Wang L, Lin Y, Huang H, Wang L, Wang L, Kohli M. Abstract 2733: Comparison of copy number aberrations (CNAs) between plasma cell free DNA (cfDNA) and tissue DNA in metastatic castrate resistant prostate cancer (mCRPC) Cancer Research. 77: 2733-2733. DOI: 10.1158/1538-7445.Am2017-2733 |
0.309 |
|
2016 |
Niu N, Liu T, Cairns J, Ly RC, Tan X, Deng M, Fridley BL, Kalari KR, Abo RP, Jenkins G, Batzler A, Carlson EE, Barman P, Moran S, Heyn H, ... ... Wang L, et al. Metformin pharmacogenomics: a genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines. Human Molecular Genetics. 25: 4819-4834. PMID 28173075 DOI: 10.1093/Hmg/Ddw301 |
0.36 |
|
2016 |
Nair AA, Niu N, Tang X, Thompson KJ, Wang L, Kocher JP, Subramanian S, Kalari KR. Circular RNAs and their associations with breast cancer subtypes. Oncotarget. PMID 27829232 DOI: 10.18632/Oncotarget.13134 |
0.414 |
|
2016 |
Ingle JN, Xie F, Ellis MJ, Goss PE, Shepherd LE, Chapman JW, Chen BE, Kubo M, Furukawa Y, Momozawa Y, Stearns V, Pritchard KI, Barman P, Carlson EE, Goetz MP, ... ... Wang L, et al. Genetic polymorphisms in the long noncoding RNA MIR2052HG offer a pharmacogenomic basis for the response of breast cancer patients to aromatase inhibitor therapy. Cancer Research. PMID 27758888 DOI: 10.1158/0008-5472.Can-16-1371 |
0.481 |
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2016 |
Li L, Zhang JW, Jenkins G, Xie F, Carlson EE, Fridley BL, Bamlet WR, Petersen GM, McWilliams RR, Wang L. Genetic variations associated with gemcitabine treatment outcome in pancreatic cancer. Pharmacogenetics and Genomics. PMID 27749787 DOI: 10.1097/Fpc.0000000000000241 |
0.385 |
|
2016 |
Niu N, Liu T, Cairns J, Ly RC, Tan X, Deng M, Fridley BL, Kalari KR, Abo RP, Jenkins G, Batzler A, Carlson EE, Barman P, Moran S, Heyn H, ... ... Wang L, et al. Metformin Pharmacogenomics: A genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines. Human Molecular Genetics. PMID 27616566 DOI: 10.1093/hmg/ddw301 |
0.361 |
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2016 |
Park JH, Jang M, Tarhan YE, Katagiri T, Sasa M, Miyoshi Y, Kalari KR, Suman VJ, Weinshilboum R, Wang L, Boughey JC, Goetz MP, Nakamura Y. Clonal expansion of antitumor T cells in breast cancer correlates with response to neoadjuvant chemotherapy. International Journal of Oncology. PMID 27278091 DOI: 10.3892/Ijo.2016.3540 |
0.366 |
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2016 |
Hart SN, Ellingson MS, Schahl K, Vedell PT, Carlson RE, Sinnwell JP, Barman P, Sicotte H, Eckel-Passow JE, Wang L, Kalari KR, Qin R, Kruisselbrink TM, Jimenez RE, Bryce AH, ... ... Wang L, et al. Determining the frequency of pathogenic germline variants from exome sequencing in patients with castrate-resistant prostate cancer. Bmj Open. 6: e010332. PMID 27084275 DOI: 10.1136/Bmjopen-2015-010332 |
0.324 |
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2016 |
Gupta M, Neavin D, Liu D, Biernacka J, Hall-Flavin D, Bobo WV, Frye MA, Skime M, Jenkins GD, Batzler A, Kalari K, Matson W, Bhasin SS, Zhu H, Mushiroda T, ... ... Wang L, et al. TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics. Molecular Psychiatry. PMID 26903268 DOI: 10.1038/Mp.2016.6 |
0.374 |
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2016 |
Kohli M, Hillman DW, Carlson R, Wang L, Li Y, Tan W, Ho TH, Sicotte H, Wang L, Costello BA, Pitot HC, Quevedo F, Dronca RS, Moynihan TJ, Atwell TD, et al. Association of androgen receptor V9 (ARV9) mRNA expression in metastatic tissue with early resistance to pre-chemotherapy abiraterone acetate/prednisone (AA/P). Journal of Clinical Oncology. 34: 237-237. DOI: 10.1200/Jco.2016.34.2_Suppl.237 |
0.327 |
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2016 |
Kohli M, Hillman DW, Wang L, Li Y, Sicotte H, Carlson R, Tan W, Wu K, Eiken PW, Jimenez RE, Cernigliaro J, Quevedo F, Costello BA, Pitot HC, Moynihan TJ, ... ... Wang L, et al. Association of androgen receptor variant 9 (AR-V9) mRNA expression levels in metastatic tissue with resistance to abiraterone acetate/prednisone (AA/P). Journal of Clinical Oncology. 34: 5036-5036. DOI: 10.1200/Jco.2016.34.15_Suppl.5036 |
0.339 |
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2016 |
Xie F, Kohli M, Ping Y, Jimenez RE, Weinshilboum RM, Wang L. Abstract A05: Developing patient derived xenograft (PDX) models for metastatic castration resistant prostate cancer (CRPC) during CYP17 inhibitor therapy Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Pdx16-A05 |
0.371 |
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2016 |
Peddi P, Hurvitz S, Fasching P, Wang L, Cunningham J, Weinshilboum R, Liu D, Quinaux E, Fourmanoir H, Robert N, Valero V, Crown J, Falkson C, Brufsky A, Pienkowski T, et al. Abstract P6-03-09: Genetic polymorphism and correlation with treatment induced cardiotoxicity and prognosis inHER2amplified early breast cancer patients Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P6-03-09 |
0.31 |
|
2016 |
Ruddy K, Rack B, Schwitulla J, Lambrechts D, Haeberle L, Schramm A, Trapp E, Scholz C, Beutler A, Ginsburg E, Couch F, Partridge A, Wang L, Weinshilboum R, Janni W, et al. Abstract P4-10-07: Genetic predictors of chemotherapy-related amenorrhea Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P4-10-07 |
0.332 |
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2016 |
Moyer A, Boughey J, Kalari K, Suman V, McLaughlin S, Moreno-Aspitia A, Northfelt D, Gray R, Sinnwell J, Carlson E, Dockter T, Jones K, Felten S, Conners A, Wieben E, ... ... Wang L, et al. Abstract P4-04-05: Differential mRNA expression patterns in breast tumors with high vs. low quantity of stromal tumor–Infiltrating lymphocytes Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P4-04-05 |
0.316 |
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2016 |
Yu J, Qin B, Boughey J, Moyer A, Visscher D, Sinnwell J, Yin P, Thompson K, Docter T, Kalari K, Suman V, Wieben E, Felten S, Conners A, Jones K, ... ... Wang L, et al. Abstract P3-07-51: Regulation of DNA methyltransferases via TRAF6 determines breast cancer response to decitabine Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-07-51 |
0.323 |
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2015 |
Kohli M, Wang L, Xie F, Sicotte H, Yin P, Dehm SM, Hart SN, Vedell PT, Barman P, Qin R, Mahoney DW, Carlson RE, Eckel-Passow JE, Atwell TD, Eiken PW, ... ... Wang L, et al. Mutational Landscapes of Sequential Prostate Metastases and Matched Patient Derived Xenografts during Enzalutamide Therapy. Plos One. 10: e0145176. PMID 26695660 DOI: 10.1371/Journal.Pone.0145176 |
0.373 |
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2015 |
Liu T, Fang Y, Zhang H, Deng M, Gao B, Niu N, Yu J, Lee S, Kim J, Qin B, Xie F, Evans DL, Wang L, Lou W, Lou Z. HEATR1 negatively regulates Akt to help sensitize pancreatic cancer cells to chemotherapy. Cancer Research. PMID 26676747 DOI: 10.1158/0008-5472.Can-15-0671 |
0.311 |
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2015 |
Kim JJ, Lee SB, Jang J, Yi SY, Kim SH, Han SA, Lee JM, Tong SY, Vincelette ND, Gao B, Yin P, Evans D, Choi DW, Qin B, Liu T, ... ... Wang L, et al. WSB1 promotes tumor metastasis by inducing pVHL degradation. Genes & Development. 29: 2244-57. PMID 26545811 DOI: 10.1101/Gad.268128.115 |
0.323 |
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2015 |
Hanson C, Cairns J, Wang L, Sinha S. Computational discovery of transcription factors associated with drug response. The Pharmacogenomics Journal. PMID 26503816 DOI: 10.1038/Tpj.2015.74 |
0.422 |
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2015 |
Ellingson MS, Hart SN, Kalari KR, Suman V, Schahl KA, Dockter TJ, Felten SJ, Sinnwell JP, Thompson KJ, Tang X, Vedell PT, Barman P, Sicotte H, Eckel-Passow JE, Northfelt DW, ... ... Wang L, et al. Exome sequencing reveals frequent deleterious germline variants in cancer susceptibility genes in women with invasive breast cancer undergoing neoadjuvant chemotherapy. Breast Cancer Research and Treatment. 153: 435-43. PMID 26296701 DOI: 10.1007/S10549-015-3545-6 |
0.369 |
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2015 |
Hein A, Lambrechts D, von Minckwitz G, Häberle L, Eidtmann H, Tesch H, Untch M, Hilfrich J, Schem C, Rezai M, Gerber B, Dan Costa S, Blohmer JU, Schwedler K, Kittel K, ... ... Wang L, et al. Genetic variants in VEGF pathway genes in neoadjuvant breast cancer patients receiving bevacizumab: Results from the randomized phase III GeparQuinto study. International Journal of Cancer. Journal International Du Cancer. 137: 2981-8. PMID 26100253 DOI: 10.1002/ijc.29656 |
0.319 |
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2015 |
Cairns J, Peng Y, Yee VC, Lou Z, Wang L. Bora downregulation results in radioresistance by promoting repair of double strand breaks. Plos One. 10: e0119208. PMID 25742493 DOI: 10.1371/Journal.Pone.0119208 |
0.335 |
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2015 |
Qin B, Minter-Dykhouse K, Yu J, Zhang J, Liu T, Zhang H, Lee S, Kim J, Wang L, Lou Z. DBC1 functions as a tumor suppressor by regulating p53 stability. Cell Reports. 10: 1324-34. PMID 25732823 DOI: 10.1016/J.Celrep.2015.01.066 |
0.344 |
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2015 |
Niu N, Wang L. In vitro human cell line models to predict clinical response to anticancer drugs. Pharmacogenomics. 16: 273-85. PMID 25712190 DOI: 10.2217/Pgs.14.170 |
0.337 |
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2015 |
Vachon CM, Schaid DJ, Ingle JN, Wickerham DL, Kubo M, Mushiroda T, Goetz MP, Carlson EE, Paik S, Wolmark N, Nakamura Y, Wang L, Weinshilboum R, Couch FJ. A polygenic risk score for breast cancer in women receiving tamoxifen or raloxifene on NSABP P-1 and P-2. Breast Cancer Research and Treatment. 149: 517-23. PMID 25575444 DOI: 10.1007/S10549-014-3175-4 |
0.38 |
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2015 |
Jimenez RE, Sicotte H, Barman P, Sinnwell JP, Eiken PW, Atwell TD, McMenomy BP, Tan W, Wu K, Bryce AH, Ho TH, Pitot HC, Quevedo F, Costello BA, Dronca RS, ... ... Wang L, et al. Feasibility analysis of pathology and genetic yield from a prospective trial of tissue biopsies in metastatic castrate-resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 33: 249-249. DOI: 10.1200/Jco.2015.33.7_Suppl.249 |
0.305 |
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2015 |
Kohli M, Wang L, Sicotte H, Qin R, Carlson R, Eckel-Passow J, Tan W, Wu K, Dehm S, Eiken PW, Jimenez RE, Cernigliaro J, Quevedo F, Costello BA, Pitot HC, ... ... Wang L, et al. Androgen receptor (AR) based biomarker association with response to abiraterone acetate/prednisone (AA/P) in metastatic castrate resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 33: 174-174. DOI: 10.1200/Jco.2015.33.7_Suppl.174 |
0.357 |
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2015 |
Kohli M, Qin R, Wang L, Sicotte H, Carlson R, Tan W, Jimenez RE, Wang L, Eckel-Passow J, Costello BA, Pitot HC, Quevedo F, Dronca RS, Wu K, Moynihan TJ, et al. A molecular and clinico-pathological model for predicting abiraterone acetate/prednisone (AA/P) efficacy in metastatic castrate resistant prostate cancer (mCRPC). Journal of Clinical Oncology. 33: 5056-5056. DOI: 10.1200/Jco.2015.33.15_Suppl.5056 |
0.335 |
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2015 |
Goetz MP, Barrett MT, Kalari KR, Suman VJ, McLaughlin SA, Moreno-Aspitia A, Moyer AM, Northfelt DW, Gray RJ, Sinnwell J, Mahoney D, Barman P, Vedell P, Tang X, Thompson K, ... ... Wang L, et al. Abstract PD3-3: Impact of neoadjuvant chemotherapy on the clonal composition of breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-Pd3-3 |
0.427 |
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2015 |
Vachon CM, Schaid DJ, Ingle JN, Goetz MP, Wickerham DL, Kubo M, Carlson EE, Paik S, Wolmark N, Nakamura Y, Wang L, Weinshilboum RM, Couch FJ. Abstract P6-10-03: The contribution of common genetic variation to breast cancer risk among women receiving tamoxifen or raloxifene within the National Surgical Adjuvant Breast and Bowel Project (NSABP) P-1 and P-2 trials Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P6-10-03 |
0.39 |
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2015 |
Breitenstein MK, Ho M, Weinshilboum RM, Cerhan JR, Pathak J, Bongartz T, Wang L, Ingle JN. Abstract LB-191: Association of anti-estrogen therapy in breast cancer patients and subsequent risk of rheumatoid arthritis: An electronic health record study Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-191 |
0.338 |
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2015 |
Bidadi B, Kalari KR, Rubner M, Hein A, Beckmann MW, Fasching PA, Rack B, Janni W, Weinshilboum R, Wang L. Abstract 5488: Utilizing a pathway based analysis of genome wide association data to identify biomarkers of toxicity in breast cancer patients Cancer Research. 75: 5488-5488. DOI: 10.1158/1538-7445.Am2015-5488 |
0.407 |
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2015 |
Breitenstein MK, Slager SL, Novak AJ, Maurer MJ, Thompson CA, Farooq U, Link BK, Habermann TM, Olswold CL, Feldman AL, Nowakowski GS, Ansell SM, Witzig TE, Weinshilboum RM, Wang L, et al. Abstract B143: Pharmacogenomic of refractory response to R-CHOP therapy in diffuse large B-cell lymphoma (DLBCL) patients Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-B143 |
0.348 |
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2014 |
Tong Y, Niu N, Jenkins G, Batzler A, Li L, Kalari KR, Wang L. Identification of genetic variants or genes that are associated with Homoharringtonine (HHT) response through a genome-wide association study in human lymphoblastoid cell lines (LCLs). Frontiers in Genetics. 5: 465. PMID 25628645 DOI: 10.3389/Fgene.2014.00465 |
0.431 |
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2014 |
Tang X, Baheti S, Shameer K, Thompson KJ, Wills Q, Niu N, Holcomb IN, Boutet SC, Ramakrishnan R, Kachergus JM, Kocher JP, Weinshilboum RM, Wang L, Thompson EA, Kalari KR. The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data. Nucleic Acids Research. 42: e172. PMID 25352556 DOI: 10.1093/Nar/Gku1005 |
0.387 |
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2014 |
Pu X, Wang L, Chang JY, Hildebrandt MA, Ye Y, Lu C, Skinner HD, Niu N, Jenkins GD, Komaki R, Minna JD, Roth JA, Weinshilboum RM, Wu X. Inflammation-related genetic variants predict toxicity following definitive radiotherapy for lung cancer. Clinical Pharmacology and Therapeutics. 96: 609-15. PMID 25054431 DOI: 10.1038/Clpt.2014.154 |
0.392 |
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2014 |
Williams SR, Yang Q, Chen F, Liu X, Keene KL, Jacques P, Chen WM, Weinstein G, Hsu FC, Beiser A, Wang L, Bookman E, Doheny KF, Wolf PA, Zilka M, et al. Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke. Plos Genetics. 10: e1004214. PMID 24651765 DOI: 10.1371/Journal.Pgen.1004214 |
0.339 |
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2014 |
Zhou W, Lv R, Qi W, Wu D, Xu Y, Liu W, Mou Y, Wang L. Snail contributes to the maintenance of stem cell-like phenotype cells in human pancreatic cancer. Plos One. 9: e87409. PMID 24489910 DOI: 10.1371/Journal.Pone.0087409 |
0.343 |
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2014 |
Li L, Fridley BL, Kalari K, Niu N, Jenkins G, Batzler A, Abo RP, Schaid D, Wang L. Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines Bmc Genomics. 15. PMID 24483146 DOI: 10.1186/1471-2164-15-93 |
0.421 |
|
2014 |
Fridley BL, Abo R, Tan XL, Jenkins GD, Batzler A, Moyer AM, Biernacka JM, Wang L. Integrative gene set analysis: Application to platinum pharmacogenomics Omics a Journal of Integrative Biology. 18: 34-41. PMID 24199607 DOI: 10.1089/Omi.2013.0099 |
0.427 |
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2014 |
Dudenkov TM, Ingle JN, Buzdar A, Robson ME, Kubo M, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Fridley BL, Goetz MP, Northfelt DW, Perez EA, Williard CV, Kalari KR, ... ... Wang L, et al. Genes associated with serum estrone, estrone conjugates, and androstenedione concentrations in postmenopausal women with estrogen receptor-positive breast cancer. Journal of Clinical Oncology. 32: 593-593. DOI: 10.1200/Jco.2014.32.15_Suppl.593 |
0.392 |
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2014 |
Boughey JC, Yu J, Yin P, Gao B, Sinnwell JP, Moyer AM, Visscher DW, Conners AL, Dockter TJ, Kalari KR, Jones KN, McLaughlin SA, Copland JA, Moreno-Aspitia A, Northfelt DW, ... ... Wang L, et al. Patient-derived xenografts from breast cancer patients before and after neoadjuvant chemotherapy: A prospective study. Journal of Clinical Oncology. 32: 11130-11130. DOI: 10.1200/Jco.2014.32.15_Suppl.11130 |
0.381 |
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2014 |
Thompson KJ, Tang X, Sun Z, Sinnwell JP, Sicotte H, Mahoney DW, Hart S, Vedell PT, Barman P, Passow JEE, Wieben ED, Ingle JN, Boughey JC, Wang L, Weinshilboum R, et al. Abstract 5592: Molecular classification of triple negative breast cancer via RNA-sequencing data Cancer Research. 74: 5592-5592. DOI: 10.1158/1538-7445.Am2014-5592 |
0.403 |
|
2014 |
Kalari KR, Tang X, Thompson KJ, Mahoney DW, Barman P, Sinnwell JP, Sicotte H, Vedell P, Hart SN, Dockter TJ, Jones KN, Conners AL, Moyer AM, Visscher DW, Yu J, ... ... Wang L, et al. Abstract 4185: Analysis of sequencing data to identify potential drug targets for an individual newly diagnosed with basal breast cancer who failed to respond to current standard neoadjuvant chemotherapy Cancer Research. 74: 4185-4185. DOI: 10.1158/1538-7445.Am2014-4185 |
0.431 |
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2014 |
Hou J, Bhinge KN, Wang L. Abstract 2782: The effect of ERRFI1 as a novel AKT regulator on cell proliferation and response to therapy is cell context dependent Cancer Research. 74: 2782-2782. DOI: 10.1158/1538-7445.Am2014-2782 |
0.329 |
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2014 |
Yu J, Yin P, Gao B, Sinnwell JP, Moyer AM, Visscher DW, Conners AL, Dockter TJ, Kalari KR, Tang X, Thompson KJ, Sicotte H, Mahoney DW, Hart SN, Vedell PT, ... ... Wang L, et al. Abstract 1195: Feasibility of using percutaneous tumor biopsies from a prospective neoadjuvant breast cancer study to develop patient derived xenografts and assessin vivochemotherapy sensitivity Cancer Research. 74: 1195-1195. DOI: 10.1158/1538-7445.Am2014-1195 |
0.368 |
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2014 |
Ho M-, Liu M, Wang L, Weinshilboum R, Bongartz T. THU0481 Aromatase Inhibitor Treatment and Musculoskeletal Adverse Events: SNP Modulated, Estrogen-Dependent Variation in Ccr6/Ccl20 Expression Annals of the Rheumatic Diseases. 73: 349-349. DOI: 10.1136/Annrheumdis-2014-Eular.5382 |
0.404 |
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2014 |
Ho M-, Wang L, Weinshilboum R, Bongartz T. OP0193 The Rheumatoid Arthritis -Risk Locus CCR6 and Its Snp-Dependent Response to Estrogen: A Possible Genomic Link between Sex Hormones and the IL-17 Inflammatory Pathway Annals of the Rheumatic Diseases. 73: 135-135. DOI: 10.1136/Annrheumdis-2014-Eular.5289 |
0.356 |
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2013 |
Jiang J, Fridley BL, Feng Q, Abo RP, Brisbin A, Batzler A, Jenkins G, Long PA, Wang L. Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system. Frontiers in Genetics. 4: 166. PMID 24009623 DOI: 10.3389/Fgene.2013.00166 |
0.432 |
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2013 |
Ellsworth KA, Eckloff BW, Li L, Moon I, Fridley BL, Jenkins GD, Carlson E, Brisbin A, Abo R, Bamlet W, Petersen G, Wieben ED, Wang L. Contribution of FKBP5 genetic variation to gemcitabine treatment and survival in pancreatic adenocarcinoma. Plos One. 8: e70216. PMID 23936393 DOI: 10.1371/Journal.Pone.0070216 |
0.723 |
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2013 |
Ingle JN, Liu M, Wickerham DL, Schaid DJ, Wang L, Mushiroda T, Kubo M, Costantino JP, Vogel VG, Paik S, Goetz MP, Ames MM, Jenkins GD, Batzler A, Carlson EE, et al. Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention. Cancer Discovery. 3: 812-25. PMID 23764426 DOI: 10.1158/2159-8290.Cd-13-0038 |
0.436 |
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2013 |
Liu M, Ingle JN, Fridley BL, Buzdar AU, Robson ME, Kubo M, Wang L, Batzler A, Jenkins GD, Pietrzak TL, Carlson EE, Goetz MP, Northfelt DW, Perez EA, Williard CV, et al. TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression. Molecular Endocrinology (Baltimore, Md.). 27: 657-70. PMID 23518928 DOI: 10.1210/Me.2012-1397 |
0.453 |
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2013 |
Ellsworth KA, Moon I, Eckloff BW, Fridley BL, Jenkins GD, Batzler A, Biernacka JM, Abo R, Brisbin A, Ji Y, Hebbring S, Wieben ED, Mrazek DA, Weinshilboum RM, Wang L. FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder. Pharmacogenetics and Genomics. 23: 156-66. PMID 23324805 DOI: 10.1097/Fpc.0B013E32835Dc133 |
0.745 |
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2013 |
Pu X, Wang L, Hildebrandt MA, Ye Y, Chang JY, Lu C, Skinner HD, Niu N, Jenkins GD, Komaki R, Minna JD, Roth JA, Weinshilboum RM, Wu X. Abstract 3626: Inflammation-related genetic variants predict radiation-induced toxicity following definitive radiotherapy for non-small cell lung cancer. Cancer Research. 73: 3626-3626. DOI: 10.1158/1538-7445.Am2013-3626 |
0.422 |
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2013 |
Niu N, Tan X, Fridley BL, Schaid DJ, Abo RP, Batzler A, Carlson EE, Jenkins G, Moran S, Heyn HA, Badosa ME, Wang L. Abstract 2271: Metformin pharmacogenomics: A genome-wide associate study to identify genetic and epigenetic biomarkers involved in metformin response. Cancer Research. 73: 2271-2271. DOI: 10.1158/1538-7445.Am2013-2271 |
0.473 |
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2013 |
Ellsworth KA, Eckloff BW, Li L, Moon I, Fridley BL, Jenkins GD, Carlson E, Brisbin A, Abo R, Bamlet W, Petersen G, Wieben ED, Wang L. Abstract 2209: Contribution ofFKBP5genetic variation to gemcitabine treatment and survival in pancreatic cancer. Cancer Research. 73: 2209-2209. DOI: 10.1158/1538-7445.Am2013-2209 |
0.763 |
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2013 |
Goetz M, Boughey J, Kalari K, Eckel-Passow J, Suman V, Sicotte H, Hart S, Moyer A, Visscher D, Yu J, Gao B, Sinnwell J, Mahoney D, Barman P, Vedell P, ... ... Wang L, et al. Abstract P1-08-10: Integration of next generation sequencing (NGS) and patient derived xenografts (PDX) to identify novel markers of paclitaxel (T) response in the breast cancer genome guided therapy study (BEAUTY) Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P1-08-10 |
0.324 |
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2012 |
Niu N, Schaid DJ, Abo RP, Kalari K, Fridley BL, Feng Q, Jenkins G, Batzler A, Brisbin AG, Cunningham JM, Li L, Sun Z, Yang P, Wang L. Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study. Bmc Cancer. 12: 422. PMID 23006423 DOI: 10.1186/1471-2407-12-422 |
0.432 |
|
2012 |
Brisbin A, Jenkins GD, Ellsworth KA, Wang L, Fridley BL. Localization of association signal from risk and protective variants in sequencing studies. Frontiers in Genetics. 3: 173. PMID 22973297 DOI: 10.3389/Fgene.2012.00173 |
0.707 |
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2012 |
Hou J, Wang L. FKBP5 as a selection biomarker for gemcitabine and Akt inhibitors in treatment of pancreatic cancer. Plos One. 7: e36252. PMID 22590527 DOI: 10.1371/Journal.Pone.0036252 |
0.351 |
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2012 |
Breheny P, Chalise P, Batzler A, Wang L, Fridley BL. Genetic association studies of copy-number variation: should assignment of copy number states precede testing? Plos One. 7: e34262. PMID 22493684 DOI: 10.1371/Journal.Pone.0034262 |
0.365 |
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2012 |
Fridley BL, Lund S, Jenkins GD, Wang L. A Bayesian integrative genomic model for pathway analysis of complex traits. Genetic Epidemiology. 36: 352-9. PMID 22460780 DOI: 10.1002/Gepi.21628 |
0.321 |
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2012 |
Liu M, Wang L, Bongartz T, Hawse JR, Markovic SN, Schaid DJ, Mushiroda T, Kubo M, Nakamura Y, Kamatani N, Goss PE, Ingle JN, Weinshilboum RM. Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression. Breast Cancer Research : Bcr. 14: R41. PMID 22405131 DOI: 10.1186/bcr3137 |
0.303 |
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2012 |
Biernacka JM, Jenkins GD, Wang L, Moyer AM, Fridley BL. Use of the gamma method for self-contained gene-set analysis of SNP data. European Journal of Human Genetics : Ejhg. 20: 565-71. PMID 22166939 DOI: 10.1038/Ejhg.2011.236 |
0.375 |
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2012 |
Innocenti F, Owzar K, Cox NL, Evans P, Kubo M, Zembutsu H, Jiang C, Hollis D, Mushiroda T, Li L, Friedman P, Wang L, Glubb D, Hurwitz H, Giacomini KM, et al. A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 577-84. PMID 22142827 DOI: 10.1158/1078-0432.Ccr-11-1387 |
0.388 |
|
2011 |
Fridley BL, Batzler A, Li L, Li F, Matimba A, Jenkins GD, Ji Y, Wang L, Weinshilboum RM. Gene set analysis of purine and pyrimidine antimetabolites cancer therapies. Pharmacogenetics and Genomics. 21: 701-12. PMID 21869733 DOI: 10.1097/Fpc.0B013E32834A48A9 |
0.325 |
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2011 |
Tan XL, Moyer AM, Fridley BL, Schaid DJ, Niu N, Batzler AJ, Jenkins GD, Abo RP, Li L, Cunningham JM, Sun Z, Yang P, Wang L. Genetic variation predicting cisplatin cytotoxicity associated with overall survival in lung cancer patients receiving platinum-based chemotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5801-11. PMID 21775533 DOI: 10.1158/1078-0432.Ccr-11-1133 |
0.32 |
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2011 |
Li Y, Sun Z, Cunningham JM, Aubry MC, Wampfler JA, Croghan GA, Johnson C, Wu D, Aakre JA, Molina J, Wang L, Pankratz VS, Yang P. Genetic variations in multiple drug action pathways and survival in advanced stage non-small cell lung cancer treated with chemotherapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3830-40. PMID 21636554 DOI: 10.1158/1078-0432.CCR-10-2877 |
0.374 |
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2011 |
Wu TY, Fridley BL, Jenkins GD, Batzler A, Wang L, Weinshilboum RM. Mycophenolic acid response biomarkers: a cell line model system-based genome-wide screen. International Immunopharmacology. 11: 1057-64. PMID 21396482 DOI: 10.1016/J.Intimp.2011.02.027 |
0.402 |
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2011 |
Lobmeyer MT, Wang L, Zineh I, Turner ST, Gums JG, Chapman AB, Cooper-DeHoff RM, Beitelshees AL, Bailey KR, Boerwinkle E, Pepine CJ, Johnson JA. Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients. Pharmacogenetics and Genomics. 21: 42-9. PMID 21127457 DOI: 10.1097/Fpc.0B013E328341E911 |
0.342 |
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2011 |
Li L, Lou Z, Wang L. The role of FKBP5 in cancer aetiology and chemoresistance British Journal of Cancer. 104: 19-23. PMID 21119664 DOI: 10.1038/Sj.Bjc.6606014 |
0.305 |
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2011 |
Liu M, Wang L, Schaid D, Wickerham DL, Costantino JP, Goetz MP, Ames MM, Vogel VG, Paik S, Batzler A, Wolmark N, Nakamura Y, Kubo M, Kamatani N, Ingle JN, et al. Abstract 4727: Breast cancer prevention and selective estrogen response modulators (SERMs): Pharmacogenomics and differential estrogen and SERM regulation of BRCA1 and BRCA2 expression Cancer Research. 71: 4727-4727. DOI: 10.1158/1538-7445.Am2011-4727 |
0.476 |
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2011 |
Hou J, Qin B, Lou Z, Wang L. Abstract 2660: Downregulation of Bora gene expression in human tumor cells results in radioresistance by promoting repair of double strand breaks Cancer Research. 71: 2660-2660. DOI: 10.1158/1538-7445.Am2011-2660 |
0.365 |
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2011 |
Tan X, Moyer AM, Schaid DJ, Niu N, Batzler A, Li L, Sun Z, Yang P, Wang L. Abstract 1285: Genetic variations predicting cisplatin cytotoxicity associated with the overall survival in lung cancer patients receiving platinum-based chemotherapy Cancer Research. 71: 1285-1285. DOI: 10.1158/1538-7445.Am2011-1285 |
0.437 |
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2011 |
Hou J, Wang L. Abstract C15: Combined blockade of AKT kinase with gemcitabine overcomes FKBP5-mediated resistance of inhibition of pancreatic tumor growth. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C15 |
0.348 |
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2011 |
Ibrahim-zada I, Ingle JN, Fridley BL, Buzdar A, Robson ME, Kubo M, Batzler A, Jenkins GD, Goetz MP, Northfelt DW, Perez EA, Williard CV, Wang L, Schaid DJ, Nakamura Y, et al. Abstract C114: Androstenedione levels in postmenopausal women with resected early-stage breast cancer are associated with SNPs in CYP11B1 and CYP11B2 identified by a genome-wide association study (GWAS). Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C114 |
0.419 |
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2010 |
Niu N, Qin Y, Fridley BL, Hou J, Kalari KR, Zhu M, Wu TY, Jenkins GD, Batzler A, Wang L. Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines. Genome Research. 20: 1482-92. PMID 20923822 DOI: 10.1101/Gr.107672.110 |
0.398 |
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2010 |
Ingle JN, Schaid DJ, Goss PE, Liu M, Mushiroda T, Chapman JA, Kubo M, Jenkins GD, Batzler A, Shepherd L, Pater J, Wang L, Ellis MJ, Stearns V, Rohrer DC, et al. Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 4674-82. PMID 20876420 DOI: 10.1200/Jco.2010.28.5064 |
0.396 |
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2010 |
Li F, Fridley BL, Matimba A, Kalari KR, Pelleymounter L, Moon I, Ji Y, Jenkins GD, Batzler A, Wang L, Weinshilboum RM. Ecto-5'-nucleotidase and thiopurine cellular circulation: association with cytotoxicity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 2329-38. PMID 20855458 DOI: 10.1124/Dmd.110.035220 |
0.42 |
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2010 |
Kalari KR, Hebbring SJ, Chai HS, Li L, Kocher JP, Wang L, Weinshilboum RM. Copy number variation and cytidine analogue cytotoxicity: a genome-wide association approach. Bmc Genomics. 11: 357. PMID 20525348 DOI: 10.1186/1471-2164-11-357 |
0.455 |
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2010 |
Wang L, Ellsworth KA, Moon I, Pelleymounter LL, Eckloff BW, Martin YN, Fridley BL, Jenkins GD, Batzler A, Suman VJ, Ravi S, Dixon JM, Miller WR, Wieben ED, Buzdar A, et al. Functional genetic polymorphisms in the aromatase gene CYP19 vary the response of breast cancer patients to neoadjuvant therapy with aromatase inhibitors. Cancer Research. 70: 319-28. PMID 20048079 DOI: 10.1158/0008-5472.Can-09-3224 |
0.764 |
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2010 |
Hou J, Niu N, Qin Y, Fridley BL, Kalari K, Jenkins G, Batzler A, Wang L. Abstract 3602: Radiation pharmacogenomics: an integrative analysis approach to identify biomarkers using the human lymphoblastoid cell lines Cancer Research. 70: 3602-3602. DOI: 10.1158/1538-7445.Am10-3602 |
0.416 |
|
2010 |
Niu N, Fridley BL, Kalari KR, Jenkins GD, Anthony B, Wang L. Abstract 2599: Taxane pharmacogenomics: Identifying genetic variation associated with drug cytotoxicity using a genome-wide association approach and a cell line model system Cancer Research. 70: 2599-2599. DOI: 10.1158/1538-7445.Am10-2599 |
0.469 |
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2010 |
Ingle J, Liu M, Wickerham D, Schaid D, Mushiroda T, Kubo M, Costantino J, Goetz M, Ames M, Wang L, Vogel V, Paik S, Batzler A, Flockhart D, Wolmark N, et al. Abstract PD05-02: Genome-Wide Associations of Breast Events and Functional Genomic Studies in High-Risk Women Receiving Tamoxifen or Raloxifene on NSABP P1 and P2 Prevention Trials. A Pharmacogenomics Research Network-RIKEN-NSABP Collaboration Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-Pd05-02 |
0.321 |
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2009 |
Li L, Fridley BL, Kalari K, Jenkins G, Batzler A, Weinshilboum RM, Wang L. Gemcitabine and arabinosylcytosin pharmacogenomics: genome-wide association and drug response biomarkers. Plos One. 4: e7765. PMID 19898621 DOI: 10.1371/Journal.Pone.0007765 |
0.332 |
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2009 |
Aksoy P, Zhu MJ, Kalari KR, Moon I, Pelleymounter LL, Eckloff BW, Wieben ED, Yee VC, Weinshilboum RM, Wang L. Cytosolic 5'-nucleotidase III (NT5C3): gene sequence variation and functional genomics. Pharmacogenetics and Genomics. 19: 567-76. PMID 19623099 DOI: 10.1097/Fpc.0B013E32832C14B8 |
0.357 |
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2009 |
Fridley BL, Jenkins G, Schaid DJ, Wang L. A Bayesian hierarchical nonlinear model for assessing the association between genetic variation and drug cytotoxicity. Statistics in Medicine. 28: 2709-22. PMID 19572260 DOI: 10.1002/Sim.3649 |
0.344 |
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2008 |
Wang L, Weinshilboum RM. Pharmacogenomics: candidate gene identification, functional validation and mechanisms. Human Molecular Genetics. 17: R174-9. PMID 18852207 DOI: 10.1093/Hmg/Ddn270 |
0.364 |
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2008 |
Li L, Fridley B, Kalari K, Jenkins G, Batzler A, Safgren S, Hildebrandt M, Ames M, Schaid D, Wang L. Gemcitabine and cytosine arabinoside cytotoxicity: association with lymphoblastoid cell expression. Cancer Research. 68: 7050-8. PMID 18757419 DOI: 10.1158/0008-5472.Can-08-0405 |
0.403 |
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2008 |
Ji Y, Olson J, Zhang J, Hildebrandt M, Wang L, Ingle J, Fredericksen Z, Sellers T, Miller W, Dixon JM, Brauch H, Eichelbaum M, Justenhoven C, Hamann U, Ko Y, et al. Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms. Cancer Research. 68: 5997-6005. PMID 18632656 DOI: 10.1158/0008-5472.Can-08-0043 |
0.441 |
|
2008 |
Wang L, Kumar S, Fridley BL, Kalari KR, Moon I, Pelleymounter LL, Hildebrandt MA, Batzler A, Eckloff BW, Wieben ED, Greipp PR. Proteasome beta subunit pharmacogenomics: gene resequencing and functional genomics. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3503-13. PMID 18519783 DOI: 10.1158/1078-0432.Ccr-07-5150 |
0.321 |
|
2007 |
Wang L, Salavaggione E, Pelleymounter L, Eckloff B, Wieben E, Weinshilboum R. Human 3beta-hydroxysteroid dehydrogenase types 1 and 2: Gene sequence variation and functional genomics. The Journal of Steroid Biochemistry and Molecular Biology. 107: 88-99. PMID 17689071 DOI: 10.1016/J.Jsbmb.2007.03.037 |
0.398 |
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2006 |
Weinshilboum RM, Wang L. Pharmacogenetics and pharmacogenomics: development, science, and translation. Annual Review of Genomics and Human Genetics. 7: 223-45. PMID 16948615 DOI: 10.1146/Annurev.Genom.6.080604.162315 |
0.325 |
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2006 |
Wood TC, Salavagionne OE, Mukherjee B, Wang L, Klumpp AF, Thomae BA, Eckloff BW, Schaid DJ, Wieben ED, Weinshilboum RM. Human arsenic methyltransferase (AS3MT) pharmacogenetics: Gene resequencing and functional genomics studies Journal of Biological Chemistry. 281: 7364-7373. PMID 16407288 DOI: 10.1074/Jbc.M512227200 |
0.363 |
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2005 |
Ma CX, Adjei AA, Salavaggione OE, Coronel J, Pelleymounter L, Wang L, Eckloff BW, Schaid D, Wieben ED, Adjei AA, Weinshilboum RM. Human aromatase: gene resequencing and functional genomics. Cancer Research. 65: 11071-82. PMID 16322257 DOI: 10.1158/0008-5472.Can-05-1218 |
0.418 |
|
2005 |
Ji Y, Salavaggione OE, Wang L, Adjei AA, Eckloff B, Wieben ED, Weinshilboum RM. Human phenylethanolamine N-methyltransferase pharmacogenomics: gene re-sequencing and functional genomics. Journal of Neurochemistry. 95: 1766-76. PMID 16277617 DOI: 10.1111/J.1471-4159.2005.03453.X |
0.388 |
|
2005 |
Salavaggione OE, Wang L, Wiepert M, Yee VC, Weinshilboum RM. Thiopurine S-methyltransferase pharmacogenetics: variant allele functional and comparative genomics. Pharmacogenetics and Genomics. 15: 801-15. PMID 16220112 DOI: 10.1097/01.Fpc.0000174788.69991.6B |
0.341 |
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2005 |
Wang L, Nguyen TV, McLaughlin RW, Sikkink LA, Ramirez-Alvarado M, Weinshilboum RM. Human thiopurine S-methyltransferase pharmacogenetics: variant allozyme misfolding and aggresome formation. Proceedings of the National Academy of Sciences of the United States of America. 102: 9394-9. PMID 15967990 DOI: 10.1073/Pnas.0502352102 |
0.331 |
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2005 |
MA C, ADJEI A, SALAVAGGIONE O, WANG L, ECKLOFF B, WIEBEN E, ADJEI A, WEINSHILBOUM R. Human aromatase (CYP19) pharmacogenomics: Gene resequencing and functional genomics Clinical Pharmacology & Therapeutics. 77: P22-P22. DOI: 10.1016/J.Clpt.2004.11.085 |
0.447 |
|
2002 |
Salavaggione OE, Kidd L, Prondzinski JL, Szumlanski CL, Pankratz VS, Wang L, Trepanier L, Weinshilboum RM. Canine red blood cell thiopurine S-methyltransferase: companion animal pharmacogenetics. Pharmacogenetics. 12: 713-24. PMID 12464800 DOI: 10.1097/00008571-200212000-00005 |
0.389 |
|
2002 |
Wang L, Thomae B, Eckloff B, Wieben E, Weinshilboum R. Human histamine N-methyltransferase pharmacogenetics: Gene resequencing, promoter characterization, and functional studies of a common 5′-flanking region single nucleotide polymorphism (SNP) Biochemical Pharmacology. 64: 699-710. PMID 12167489 DOI: 10.1016/S0006-2952(02)01223-6 |
0.408 |
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