| Year |
Citation |
Score |
| 2018 |
Sai KKS, Sattiraju A, Zachar Z, Dahan MS, Shorr R, Pardee TS, Bingham PM, Mintz A. Abstract 4861: Initial preclinical evaluation of a novel inhibitor of mitochondrial metabolism against prostate cancer Cancer Research. 78: 4861-4861. DOI: 10.1158/1538-7445.Am2018-4861 |
0.333 |
|
| 2017 |
Alistar A, Morris BB, Desnoyer R, Klepin HD, Hosseinzadeh K, Clark C, Cameron A, Leyendecker J, D'Agostino R, Topaloglu U, Boteju LW, Boteju AR, Shorr R, Zachar Z, Bingham PM, et al. Safety and tolerability of the first-in-class agent CPI-613 in combination with modified FOLFIRINOX in patients with metastatic pancreatic cancer: a single-centre, open-label, dose-escalation, phase 1 trial. The Lancet. Oncology. PMID 28495639 DOI: 10.1016/S1470-2045(17)30314-5 |
0.331 |
|
| 2017 |
Sai KKS, Zachar Z, Bingham PM, Mintz A. Metabolic PET Imaging in Oncology. Ajr. American Journal of Roentgenology. 1-7. PMID 28463521 DOI: 10.2214/Ajr.17.18112 |
0.341 |
|
| 2017 |
Sai KS, Zachar Z, Almaguel F, Stuart SD, Dahan MS, Guardado M, Rideout S, Wang M, Sattiraju A, Bingham PM, Pasche B, Mintz A. Abstract 2867: FDG-PET imaging as a potential biomarker of mitochondrial targeting by CPI-613, a novel inhibitor of mitochondrial metabolism Cancer Research. 77: 2867-2867. DOI: 10.1158/1538-7445.Am2017-2867 |
0.314 |
|
| 2016 |
Stuart SD, Guardado M, Dahan M, Bingham PM, Zachar Z. Abstract A61: Tumor metabolic remodeling can modulate anticancer drug response: CPI-613 attack on tumor cell mitochondrial metabolism is mediated by metabolite availability Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A61 |
0.422 |
|
| 2014 |
Bingham PM, Stuart SD, Zachar Z. Lipoic acid and lipoic acid analogs in cancer metabolism and chemotherapy. Expert Review of Clinical Pharmacology. 7: 837-46. PMID 25284345 DOI: 10.1586/17512433.2014.966816 |
0.392 |
|
| 2014 |
Stuart SD, Schauble A, Gupta S, Kennedy AD, Keppler BR, Bingham PM, Zachar Z. A strategically designed small molecule attacks alpha-ketoglutarate dehydrogenase in tumor cells through a redox process. Cancer & Metabolism. 2: 4. PMID 24612826 DOI: 10.1186/2049-3002-2-4 |
0.367 |
|
| 2012 |
Stuart SD, Zachar Z, Gupta S, Rodriguez R, Shorr R, Bingham PM. Abstract 1122: Lipoic acid analogs induce ROS, leading to potent mitochondrial enzyme inhibition, metabolic dysfunction and cell death in tumor cells Cancer Research. 72: 1122-1122. DOI: 10.1158/1538-7445.Am2012-1122 |
0.407 |
|
| 2011 |
Zachar Z, Marecek J, Maturo C, Gupta S, Stuart SD, Howell K, Schauble A, Lem J, Piramzadian A, Karnik S, Lee K, Rodriguez R, Shorr R, Bingham PM. Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo. Journal of Molecular Medicine (Berlin, Germany). 89: 1137-48. PMID 21769686 DOI: 10.1007/S00109-011-0785-8 |
0.408 |
|
| 1994 |
Kramer J, Zachar Z, Bingham PM. Nuclear pre-mRNA metabolism: channels and tracks. Trends in Cell Biology. 4: 35-7. PMID 14731863 DOI: 10.1016/0962-8924(94)90001-9 |
0.343 |
|
| 1994 |
Zachar Z, Kramer J, Bingham PM. Looking at mRNA splicing and transport in situ. Methods in Cell Biology. 44: 599-611. PMID 7707971 DOI: 10.1016/S0091-679X(08)60934-6 |
0.333 |
|
| 1993 |
Zachar Z, Kramer J, Mims IP, Bingham PM. Evidence for channeled diffusion of pre-mRNAs during nuclear RNA transport in metazoans. The Journal of Cell Biology. 121: 729-42. PMID 8491768 DOI: 10.1083/Jcb.121.4.729 |
0.349 |
|
| 1988 |
Bingham PM, Chou TB, Mims I, Zachar Z. On/off regulation of gene expression at the level of splicing. Trends in Genetics : Tig. 4: 134-8. PMID 2853467 DOI: 10.1016/0168-9525(88)90136-9 |
0.333 |
|
| 1987 |
Zachar Z, Garza D, Chou TB, Goland J, Bingham PM. Molecular cloning and genetic analysis of the suppressor-of-white-apricot locus from Drosophila melanogaster. Molecular and Cellular Biology. 7: 2498-505. PMID 3039348 DOI: 10.1128/Mcb.7.7.2498 |
0.317 |
|
| 1987 |
Zachar Z, Chou T, Bingham PM. Evidence that a regulatory gene autoregulates splicing of its transcript. The Embo Journal. 6: 4105-4111. DOI: 10.1002/J.1460-2075.1987.Tb02756.X |
0.334 |
|
| 1987 |
Chou T, Zachar Z, Bingham PM. Developmental expression of a regulatory gene is programmed at the level of splicing. The Embo Journal. 6: 4095-4104. DOI: 10.1002/J.1460-2075.1987.Tb02755.X |
0.355 |
|
| 1985 |
Zachar Z, Chapman CH, Bingham PM. On the molecular basis of transvection effects and the regulation of transcription. Cold Spring Harbor Symposia On Quantitative Biology. 50: 337-346. PMID 3868483 DOI: 10.1101/Sqb.1985.050.01.043 |
0.307 |
|
| 1985 |
Bingham PM, Zachar Z. Evidence that two mutations, wDZL and z1, affecting synapsis-dependent genetic behavior of white are transcriptional regulatory mutations. Cell. 40: 819-25. PMID 2580637 DOI: 10.1016/0092-8674(85)90341-1 |
0.34 |
|
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