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Xingsheng Shu, Ph.D. - Publications

Affiliations: 
2012 Clinical Oncology The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Oncology, Genetics, Molecular Biology
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chen Y, Ying Y, Ma W, Ma H, Shi L, Gao X, Jia M, Li M, Song X, Kong W, Chen W, Zheng X, Muluh TA, Wang X, Wang M, ... Shu XS, et al. Targeting the epigenetic reader ENL inhibits super-enhancer-driven oncogenic transcription and synergizes with BET inhibition to suppress tumor progression. Cancer Research. PMID 38241700 DOI: 10.1158/0008-5472.CAN-23-1836  0.338
2023 Muluh TA, Shu XS, Ying Y. Targeting cancer metabolic vulnerabilities for advanced therapeutic efficacy. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 162: 114658. PMID 37031495 DOI: 10.1016/j.biopha.2023.114658  0.303
2023 Li L, Shu XS, Geng H, Ying J, Guo L, Luo J, Xiang T, Wu L, Ma BBY, Chan ATC, Zhu X, Ambinder RF, Tao Q. A novel tumor suppressor encoded by a 1p36.3 lncRNA functions as a phosphoinositide-binding protein repressing AKT phosphorylation/activation and promoting autophagy. Cell Death and Differentiation. PMID 36813924 DOI: 10.1038/s41418-023-01129-w  0.71
2023 Chen Y, Ying Y, Wang M, Ma C, Jia M, Shi L, Wang S, Zheng X, Chen W, Shu XS. A distal super-enhancer activates oncogenic ETS2 via recruiting MECOM in inflammatory bowel disease and colorectal cancer. Cell Death & Disease. 14: 8. PMID 36609474 DOI: 10.1038/s41419-022-05513-1  0.368
2022 Ying Y, Wang M, Chen Y, Li M, Ma C, Zhang J, Huang X, Jia M, Zeng J, Wang Y, Li L, Wang X, Tao Q, Shu XS. Zinc finger protein 280C contributes to colorectal tumorigenesis by maintaining epigenetic repression at H3K27me3-marked loci. Proceedings of the National Academy of Sciences of the United States of America. 119: e2120633119. PMID 35605119 DOI: 10.1073/pnas.2120633119  0.509
2021 Liu S, Jiang Y, Yang H, Hua Z, Han Y, Zhou C, Xu S, Nie S, Xu G, Shu X, Wang X. BIX-01294 enhances the effect of chemotherapy on colorectal cancer by inhibiting the expression of stemness genes. Biochemical and Biophysical Research Communications. 590: 169-176. PMID 34979318 DOI: 10.1016/j.bbrc.2021.12.089  0.31
2020 Zhang J, Ying Y, Li M, Wang M, Huang X, Jia M, Zeng J, Ma C, Zhang Y, Li C, Wang X, Shu XS. Targeted inhibition of KDM6 histone demethylases eradicates tumor-initiating cells via enhancer reprogramming in colorectal cancer. Theranostics. 10: 10016-10030. PMID 32929331 DOI: 10.7150/Thno.47081  0.528
2020 Zhang Y, Cheng Y, Zhang Z, Bai Z, Jin H, Guo X, Huang X, Li M, Wang M, Shu XS, Yuan Y, Ying Y. CDCA2 Inhibits Apoptosis and Promotes Cell Proliferation in Prostate Cancer and Is Directly Regulated by HIF-1α Pathway. Frontiers in Oncology. 10: 725. PMID 32509575 DOI: 10.3389/Fonc.2020.00725  0.494
2020 Zhao Y, Zhu H, Yang Y, Ye Y, Yao Y, Huang X, Zhang Y, Shu X, Chen X, Yang Y, Ma J, Cheng L, Wang X, Ying Y. AQP1 suppression by ATF4 triggers trabecular meshwork tissue remodelling in ET-1-induced POAG. Journal of Cellular and Molecular Medicine. PMID 32052937 DOI: 10.1111/Jcmm.15032  0.335
2019 Li L, Fan Y, Huang X, Luo J, Zhong L, Shu XS, Lu L, Xiang T, Chan ATC, Yeo W, Chen C, Chan WY, Huganir RL, Tao Q. Tumor Suppression of Ras GTPase-Activating Protein RASA5 through Antagonizing Ras Signaling Perturbation in Carcinomas. Iscience. 21: 1-18. PMID 31654850 DOI: 10.1016/J.Isci.2019.10.007  0.722
2019 Ying Y, Wang Y, Huang X, Sun Y, Zhang J, Li M, Zeng J, Wang M, Xiao W, Zhong L, Xu B, Li L, Tao Q, Wang X, Shu XS. Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1. Oncogene. PMID 31591481 DOI: 10.1038/S41388-019-1013-1  0.57
2018 Shu X, Wang D, Zhao Y, Sun Y, Hu X, Huang X, Zeng J, Li C, Li Y, Zeng Y, Wang X, He Z, Ying Y. Extract from Moringa oleifera seeds suppresses the epithelial-mesenchymal transition-mediated metastasis of gastric cancer by targeting the metastatic suppressor NDRG1 Journal of Functional Foods. 50: 93-103. DOI: 10.1016/J.Jff.2018.09.030  0.397
2017 Shu XS, Zhao Y, Sun Y, Zhong L, Cheng Y, Zhang Y, Ning K, Tao Q, Wang Y, Ying Y. PBRM1 restricts the basal activity of innate immune system through repressing RIG-I-like receptor signaling and is a potential prognostic biomarker for colon cancer. The Journal of Pathology. PMID 28940253 DOI: 10.1002/Path.4986  0.54
2017 Hu X, Kuang Y, Li L, Tang H, Shi Q, Shu X, Zhang Y, Chan FK, Tao Q, He C. Epigenomic and Functional Characterization of Junctophilin 3 (JPH3) as a Novel Tumor Suppressor Being Frequently Inactivated by Promoter CpG Methylation in Digestive Cancers. Theranostics. 7: 2150-2163. PMID 28656064 DOI: 10.7150/Thno.18185  0.681
2017 Zhang Y, Yuan Y, Liang P, Zhang Z, Guo X, Xia L, Zhao Y, Shu XS, Sun S, Ying Y, Cheng Y. Overexpression of a novel candidate oncogene KIF14 correlates with tumor progression and poor prognosis in prostate cancer. Oncotarget. PMID 28525372 DOI: 10.18632/Oncotarget.17564  0.462
2017 Zhang Y, Yuan Y, Liang P, Guo X, Ying Y, Shu XS, Jr MG, Cheng Y. OSR1 is a novel epigenetic silenced tumor suppressor regulating invasion and proliferation in renal cell carcinoma. Oncotarget. PMID 28404905 DOI: 10.18632/Oncotarget.15611  0.558
2016 Zhang WJ, Wu XN, Shi TT, Xu HT, Yi J, Shen HF, Huang MF, Shu XY, Wang FF, Peng BL, Xiao RQ, Gao WW, Ding JC, Liu W. Regulation of Transcription Factor Yin Yang 1 by SET7/9-mediated Lysine Methylation. Scientific Reports. 6: 21718. PMID 26902152 DOI: 10.1038/srep21718  0.317
2015 Shu Xs. Emerging role of PR domain containing 5 (PRDM5) as a broad tumor suppressor in human cancers Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 36: 1-3. PMID 25501702 DOI: 10.1007/S13277-014-2916-7  0.443
2014 Li L, Ying J, Tong X, Zhong L, Su X, Xiang T, Shu X, Rong R, Xiong L, Li H, Chan AT, Ambinder RF, Guo Y, Tao Q. Epigenetic identification of receptor tyrosine kinase-like orphan receptor 2 as a functional tumor suppressor inhibiting β-catenin and AKT signaling but frequently methylated in common carcinomas. Cellular and Molecular Life Sciences : Cmls. 71: 2179-92. PMID 24158497 DOI: 10.1007/S00018-013-1485-Z  0.742
2013 Shu XS, Li L, Ji M, Cheng Y, Ying J, Fan Y, Zhong L, Liu X, Tsao SW, Chan AT, Tao Q. FEZF2, a novel 3p14 tumor suppressor gene, represses oncogene EZH2 and MDM2 expression and is frequently methylated in nasopharyngeal carcinoma. Carcinogenesis. 34: 1984-93. PMID 23677067 DOI: 10.1093/Carcin/Bgt165  0.764
2013 Yin X, Xiang T, Li L, Su X, Shu X, Luo X, Huang J, Yuan Y, Peng W, Oberst M, Kelly K, Ren G, Tao Q. DACT1, an antagonist to Wnt/β-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer. Breast Cancer Research : Bcr. 15: R23. PMID 23497530 DOI: 10.1186/Bcr3399  0.538
2013 Hu X, Sui X, Li L, Huang X, Rong R, Su X, Shi Q, Mo L, Shu X, Kuang Y, Tao Q, He C. Protocadherin 17 acts as a tumour suppressor inducing tumour cell apoptosis and autophagy, and is frequently methylated in gastric and colorectal cancers. The Journal of Pathology. 229: 62-73. PMID 22926751 DOI: 10.1002/Path.4093  0.577
2012 Shu XS, Li L, Tao Q. Chromatin regulators with tumor suppressor properties and their alterations in human cancers. Epigenomics. 4: 537-49. PMID 23130835 DOI: 10.2217/Epi.12.50  0.573
2012 Li L, Ying J, Li H, Zhang Y, Shu X, Fan Y, Tan J, Cao Y, Tsao SW, Srivastava G, Chan ATC, Tao Q. The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/Β-catenin signaling and silenced in common carcinomas Oncogene. 31: 3901-3912. PMID 22139084 DOI: 10.1038/Onc.2011.541  0.762
2011 Shu XS, Geng H, Li L, Ying J, Ma C, Wang Y, Poon FF, Wang X, Ying Y, Yeo W, Srivastava G, Tsao SW, Yu J, Sung JJ, Huang S, et al. The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating WNT/β-catenin signaling and is frequently silenced in multiple tumors. Plos One. 6: e27346. PMID 22087297 DOI: 10.1371/Journal.Pone.0027346  0.757
2011 Li LL, Shu XS, Wang ZH, Cao Y, Tao Q. Epigenetic disruption of cell signaling in nasopharyngeal carcinoma. Chinese Journal of Cancer. 30: 231-9. PMID 21439244 DOI: 10.5732/Cjc.011.10080  0.555
2011 Low JS, Tao Q, Ng KM, Goh HK, Shu XS, Woo WL, Ambinder RF, Srivastava G, Shamay M, Chan AT, Popescu NC, Hsieh WS. A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors. Oncogene. 30: 1923-35. PMID 21217778 DOI: 10.1038/Onc.2010.576  0.689
2009 Wang Y, Li J, Cui Y, Li T, Ng KM, Geng H, Li H, Shu XS, Li H, Liu W, Luo B, Zhang Q, Mok TS, Zheng W, Qiu X, et al. CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis. Cancer Research. 69: 5194-201. PMID 19509237 DOI: 10.1158/0008-5472.Can-08-3694  0.71
2009 Hu XT, Zhang FB, Fan YC, Shu XS, Wong AH, Zhou W, Shi QL, Tang HM, Fu L, Guan XY, Rha SY, Tao Q, He C. Phospholipase C delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer. Oncogene. 28: 2466-75. PMID 19448674 DOI: 10.1038/Onc.2009.92  0.752
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