| Year |
Citation |
Score |
| 2024 |
Gedam M, Zheng H. Complement C3aR signaling: Immune and metabolic modulation and its impact on Alzheimer's disease. European Journal of Immunology. e2350815. PMID 38778507 DOI: 10.1002/eji.202350815 |
0.373 |
|
| 2023 |
Wang B, Martini-Stoica H, Qi C, Lu TC, Wang S, Xiong W, Qi Y, Xu Y, Sardiello M, Li H, Zheng H. TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy. Nature Neuroscience. PMID 37985800 DOI: 10.1038/s41593-023-01494-2 |
0.756 |
|
| 2023 |
Wu Y, Du S, Bimler LH, Mauk KE, Lortal L, Kichik N, Griffiths JS, Osicka R, Song L, Polsky K, Kasper L, Sebo P, Weatherhead J, Knight JM, Kheradmand F, ... Zheng H, et al. Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis. Cell Reports. 42: 113240. PMID 37819761 DOI: 10.1016/j.celrep.2023.113240 |
0.305 |
|
| 2023 |
Comerota MM, Gedam M, Xiong W, Jin F, Deng L, Wang MC, Wang J, Zheng H. Oleoylethanolamide facilitates PPARα and TFEB signaling and attenuates Aβ pathology in a mouse model of Alzheimer's disease. Molecular Neurodegeneration. 18: 56. PMID 37580742 DOI: 10.1186/s13024-023-00648-x |
0.434 |
|
| 2023 |
Gedam M, Comerota MM, Propson NE, Chen T, Jin F, Wang MC, Zheng H. Complement C3aR depletion reverses HIF-1α-induced metabolic impairment and enhances microglial response to Aβ pathology. The Journal of Clinical Investigation. 133. PMID 37317973 DOI: 10.1172/JCI167501 |
0.353 |
|
| 2023 |
Wang B, Martini-Stoica H, Qi C, Lu TC, Wang S, Xiong W, Qi Y, Xu Y, Sardiello M, Li H, Zheng H. TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy. Biorxiv : the Preprint Server For Biology. PMID 36798205 DOI: 10.1101/2023.02.06.527293 |
0.743 |
|
| 2023 |
Comerota M, Gedam M, Xiong W, Jin F, Deng L, Wang M, Wang J, Zheng H. Oleoylethanolamide facilitates PPARa and TFEB signaling and attenuates Ab pathology in a mouse model of Alzheimer's disease. Research Square. PMID 36711875 DOI: 10.21203/rs.3.rs-2484513/v1 |
0.334 |
|
| 2023 |
Niu M, Cao W, Wang Y, Zhu Q, Luo J, Wang B, Zheng H, Weitz DA, Zong C. Droplet-based transcriptome profiling of individual synapses. Nature Biotechnology. PMID 36646931 DOI: 10.1038/s41587-022-01635-1 |
0.752 |
|
| 2022 |
Zhao P, Xu Y, Jiang L, Fan X, Li L, Li X, Arase H, Zhao Y, Cao W, Zheng H, Xu H, Tong Q, Zhang N, An Z. A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease. Science Translational Medicine. 14: eabq0095. PMID 36070367 DOI: 10.1126/scitranslmed.abq0095 |
0.448 |
|
| 2022 |
Roy ER, Chiu G, Li S, Propson NE, Kanchi R, Wang B, Coarfa C, Zheng H, Cao W. Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques. Immunity. PMID 35443157 DOI: 10.1016/j.immuni.2022.03.018 |
0.763 |
|
| 2021 |
Du S, Jin F, Maneix L, Gedam M, Xu Y, Catic A, Wang MC, Zheng H. FoxO3 deficiency in cortical astrocytes leads to impaired lipid metabolism and aggravated amyloid pathology. Aging Cell. e13432. PMID 34247441 DOI: 10.1111/acel.13432 |
0.411 |
|
| 2021 |
Xu Y, Propson NE, Du S, Xiong W, Zheng H. Autophagy deficiency modulates microglial lipid homeostasis and aggravates tau pathology and spreading. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34187889 DOI: 10.1073/pnas.2023418118 |
0.312 |
|
| 2021 |
Chen F, Swartzlander DB, Ghosh A, Fryer JD, Wang B, Zheng H. Clusterin secreted from astrocyte promotes excitatory synaptic transmission and ameliorates Alzheimer's disease neuropathology. Molecular Neurodegeneration. 16: 5. PMID 33517893 DOI: 10.1186/s13024-021-00426-7 |
0.764 |
|
| 2020 |
Ghosh A, Comerota MM, Wan D, Chen F, Propson NE, Hwang SH, Hammock BD, Zheng H. An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease. Science Translational Medicine. 12. PMID 33298560 DOI: 10.1126/scitranslmed.abb1206 |
0.381 |
|
| 2020 |
Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, ... ... Zheng H, et al. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Reports. 32: 107908. PMID 32668255 DOI: 10.1016/J.Celrep.2020.107908 |
0.359 |
|
| 2020 |
Xu Y, Du S, Marsh JA, Horie K, Sato C, Ballabio A, Karch CM, Holtzman DM, Zheng H. TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading. Molecular Psychiatry. PMID 32366951 DOI: 10.1038/S41380-020-0738-0 |
0.443 |
|
| 2020 |
Roy ER, Wang B, Wan YW, Chiu GS, Cole AL, Yin Z, Propson NE, Xu Y, Jankowsky JL, Liu Z, Lee VM, Trojanowski JQ, Ginsberg SD, Butovsky O, Zheng H, et al. Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease. The Journal of Clinical Investigation. PMID 31917687 DOI: 10.1172/Jci133737 |
0.794 |
|
| 2019 |
Roy E, Wang B, Zheng H, Cao W. TYPE I INTERFERON-MEDIATED NEUROINFLAMMATORY PROGRAM AND SYNAPSE LOSS IN ALZHEIMER’S DISEASE Innovation in Aging. 3: S92-S92. DOI: 10.1093/geroni/igz038.349 |
0.478 |
|
| 2019 |
Du S, Maneix L, Zhang Q, Wan Y, Zheng H. The Role Of Foxo3 Transcription Factor In Alzheimer’S Disease Pathology Innovation in Aging. 3. DOI: 10.1093/Geroni/Igz038.3102 |
0.314 |
|
| 2019 |
Propson NE, Litvinchuk A, Roy ER, Contreras B, Cao W, Zheng H. INCREASED C3 IN THE AGING BRAIN PROMOTES INFLAMMATORY TRANSITION IN ENDOTHELIAL CELLS Innovation in Aging. 3: S840-S840. DOI: 10.1093/geroni/igz038.3093 |
0.317 |
|
| 2018 |
Li H, Liu CC, Zheng H, Huang TY. Amyloid, tau, pathogen infection and antimicrobial protection in Alzheimer's disease -conformist, nonconformist, and realistic prospects for AD pathogenesis. Translational Neurodegeneration. 7: 34. PMID 30603085 DOI: 10.1186/s40035-018-0139-3 |
0.487 |
|
| 2018 |
Litvinchuk A, Wan YW, Swartzlander DB, Chen F, Cole A, Propson NE, Wang Q, Zhang B, Liu Z, Zheng H. Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease. Neuron. PMID 30415998 DOI: 10.1016/J.Neuron.2018.10.031 |
0.509 |
|
| 2018 |
Cao W, Zheng H. Peripheral immune system in aging and Alzheimer's disease. Molecular Neurodegeneration. 13: 51. PMID 30285785 DOI: 10.1186/s13024-018-0284-2 |
0.436 |
|
| 2018 |
Martini-Stoica H, Cole AL, Swartzlander DB, Chen F, Wan YW, Bajaj L, Bader DA, Lee VMY, Trojanowski JQ, Liu Z, Sardiello M, Zheng H. TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading. The Journal of Experimental Medicine. PMID 30108137 DOI: 10.1084/Jem.20172158 |
0.491 |
|
| 2018 |
Pan G, Chen Z, Zheng H, Zhang Y, Xu H, Bu G, Zheng H, Li Y. Compensatory Mechanisms Modulate the Neuronal Excitability in a Kainic Acid-Induced Epilepsy Mouse Model. Frontiers in Neural Circuits. 12: 48. PMID 30008664 DOI: 10.3389/Fncir.2018.00048 |
0.305 |
|
| 2018 |
Swartzlander DB, Propson NE, Roy ER, Saito T, Saido T, Wang B, Zheng H. Concurrent cell type-specific isolation and profiling of mouse brains in inflammation and Alzheimer's disease. Jci Insight. 3. PMID 29997299 DOI: 10.1172/Jci.Insight.121109 |
0.728 |
|
| 2018 |
Dai MH, Zheng H, Zeng LD, Zhang Y. The genes associated with early-onset Alzheimer's disease. Oncotarget. 9: 15132-15143. PMID 29599933 DOI: 10.18632/oncotarget.23738 |
0.37 |
|
| 2017 |
Jankowsky JL, Zheng H. Practical considerations for choosing a mouse model of Alzheimer's disease. Molecular Neurodegeneration. 12: 89. PMID 29273078 DOI: 10.1186/s13024-017-0231-7 |
0.43 |
|
| 2017 |
Li Y, Chen Z, Gao Y, Pan G, Zheng H, Zhang Y, Xu H, Bu G, Zheng H. Synaptic adhesion molecule Pcdh-γC5 mediates synaptic dysfunction in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28842416 DOI: 10.1523/Jneurosci.1051-17.2017 |
0.469 |
|
| 2017 |
Wang B, Li H, Mutlu SA, Bowser DA, Moore MJ, Wang MC, Zheng H. The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance. Eneuro. 4. PMID 28785723 DOI: 10.1523/ENEURO.0185-17.2017 |
0.781 |
|
| 2017 |
Chen M, Wang J, Jiang J, Zheng X, Justice NJ, Wang K, Li Y, Ran X, Huo Q, Zhang J, Li H, Lu N, Wang Y, Zheng H, Long C, et al. APP modulates KCC2 expression and function in hippocampal GABAergic inhibition. Elife. 6. PMID 28054918 DOI: 10.7554/Elife.20142 |
0.775 |
|
| 2017 |
Litvinchuk A, Wan Y, Cole A, Chen F, Liu Z, Zheng H. The Role Of Complement C3 And C3Ar Receptor In Tau Pathology In Alzheimer’S Disease Alzheimers & Dementia. 13: 229. DOI: 10.1016/J.Jalz.2017.07.115 |
0.342 |
|
| 2016 |
Xu Y, Martini-Stoica H, Zheng H. A seeding based cellular assay of tauopathy. Molecular Neurodegeneration. 11: 32. PMID 27112488 DOI: 10.1186/s13024-016-0100-9 |
0.368 |
|
| 2016 |
Martini-Stoica H, Xu Y, Ballabio A, Zheng H. The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective. Trends in Neurosciences. PMID 26968346 DOI: 10.1016/J.Tins.2016.02.002 |
0.378 |
|
| 2016 |
Li Y, Sun H, Chen Z, Xu H, Bu G, Zheng H. Implications of GABAergic Neurotransmission in Alzheimer's Disease. Frontiers in Aging Neuroscience. 8: 31. PMID 26941642 DOI: 10.3389/Fnagi.2016.00031 |
0.428 |
|
| 2016 |
Lian H, Litvinchuk A, Chiang AC, Aithmitti N, Jankowsky JL, Zheng H. Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 577-89. PMID 26758846 DOI: 10.1523/JNEUROSCI.2117-15.2016 |
0.498 |
|
| 2016 |
Chen M, Wang J, Jiang J, Zheng X, Justice NJ, Wang K, Ran X, Li Y, Huo Q, Zhang J, Li H, Lu N, Wang Y, Zheng H, Long C, et al. Author response: APP modulates KCC2 expression and function in hippocampal GABAergic inhibition Elife. DOI: 10.7554/Elife.20142.027 |
0.52 |
|
| 2015 |
Lian H, Zheng H. Signaling pathways regulating neuron-glia interaction and their implications in Alzheimer's disease. Journal of Neurochemistry. PMID 26546579 DOI: 10.1111/jnc.13424 |
0.406 |
|
| 2015 |
Justice NJ, Huang L, Tian JB, Cole A, Pruski M, Hunt AJ, Flores R, Zhu MX, Arenkiel BR, Zheng H. Posttraumatic stress disorder-like induction elevates β-amyloid levels, which directly activates corticotropin-releasing factor neurons to exacerbate stress responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2612-23. PMID 25673853 DOI: 10.1523/Jneurosci.3333-14.2015 |
0.713 |
|
| 2015 |
Lian H, Yang L, Cole A, Sun L, Chiang AC, Fowler SW, Shim DJ, Rodriguez-Rivera J, Taglialatela G, Jankowsky JL, Lu HC, Zheng H. NFκB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease. Neuron. 85: 101-15. PMID 25533482 DOI: 10.1016/J.Neuron.2014.11.018 |
0.717 |
|
| 2015 |
Zhu H, Wang X, Wallack M, Li H, Carreras I, Dedeoglu A, Hur JY, Zheng H, Li H, Fine R, Mwamburi M, Sun X, Kowall N, Stern RA, Qiu WQ. Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer's disease. Molecular Psychiatry. 20: 252-62. PMID 24614496 DOI: 10.1038/Mp.2014.17 |
0.43 |
|
| 2015 |
Zheng H. Nfκb and complement c3 mediated neuron-glia interaction in neuronal health and Alzheimer's disease Alzheimers & Dementia. 11: 116. DOI: 10.1016/J.Jalz.2015.07.011 |
0.346 |
|
| 2014 |
Wang B, Wang Z, Sun L, Yang L, Li H, Cole AL, Rodriguez-Rivera J, Lu HC, Zheng H. The amyloid precursor protein controls adult hippocampal neurogenesis through GABAergic interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 13314-25. PMID 25274811 DOI: 10.1523/Jneurosci.2848-14.2014 |
0.799 |
|
| 2014 |
Vassar R, Zheng H. Molecular neurodegeneration: basic biology and disease pathways. Molecular Neurodegeneration. 9: 34. PMID 25248568 DOI: 10.1186/1750-1326-9-34 |
0.329 |
|
| 2014 |
Li H, Guo Q, Inoue T, Polito VA, Tabuchi K, Hammer RE, Pautler RG, Taffet GE, Zheng H. Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow. Molecular Neurodegeneration. 9: 28. PMID 25108425 DOI: 10.1186/1750-1326-9-28 |
0.807 |
|
| 2014 |
Polito VA, Li H, Martini-Stoica H, Wang B, Yang L, Xu Y, Swartzlander DB, Palmieri M, di Ronza A, Lee VM, Sardiello M, Ballabio A, Zheng H. Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB. Embo Molecular Medicine. 6: 1142-60. PMID 25069841 DOI: 10.15252/Emmm.201303671 |
0.82 |
|
| 2014 |
Born HA, Kim JY, Savjani RR, Das P, Dabaghian YA, Guo Q, Yoo JW, Schuler DR, Cirrito JR, Zheng H, Golde TE, Noebels JL, Jankowsky JL. Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3826-40. PMID 24623762 DOI: 10.1523/Jneurosci.5171-13.2014 |
0.795 |
|
| 2013 |
Guo Q, Li H, Cole AL, Hur JY, Li Y, Zheng H. Modeling Alzheimer's disease in mouse without mutant protein overexpression: cooperative and independent effects of Aβ and tau. Plos One. 8: e80706. PMID 24278307 DOI: 10.1371/Journal.Pone.0080706 |
0.819 |
|
| 2013 |
Zhang B, Tian M, Zheng H, Zhen Y, Yue Y, Li T, Li S, Marcantonio ER, Xie Z. Effects of anesthetic isoflurane and desflurane on human cerebrospinal fluid Aβ and τ level Anesthesiology. 119: 52-60. PMID 23438677 DOI: 10.1097/ALN.0b013e31828ce55d |
0.339 |
|
| 2013 |
Zheng H. Role of APP in neuronal function Molecular Neurodegeneration. 8. DOI: 10.1186/1750-1326-8-S1-O4 |
0.533 |
|
| 2013 |
Li H, Guo Q, Inoue T, Pautler R, Taffet G, Zheng H. P4-326: Abnormal cerebral blood flow exacerbates amyloid pathology in an Alzheimer's disease knock-in mice model Alzheimer's & Dementia. 9: P852-P852. DOI: 10.1016/J.Jalz.2013.08.160 |
0.77 |
|
| 2012 |
Matrone C, Luvisetto S, La Rosa LR, Tamayev R, Pignataro A, Canu N, Yang L, Barbagallo AP, Biundo F, Lombino F, Zheng H, Ammassari-Teule M, D'Adamio L. Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance. Aging Cell. 11: 1084-93. PMID 23020178 DOI: 10.1111/Acel.12009 |
0.59 |
|
| 2012 |
Lian H, Shim DJ, Gaddam SS, Rodriguez-Rivera J, Bitner BR, Pautler RG, Robertson CS, Zheng H. IκBα deficiency in brain leads to elevated basal neuroinflammation and attenuated response following traumatic brain injury: implications for functional recovery. Molecular Neurodegeneration. 7: 47. PMID 22992283 DOI: 10.1186/1750-1326-7-47 |
0.572 |
|
| 2012 |
Wiese M, Antebi A, Zheng H. Regulation of neuronal APL-1 expression by cholesterol starvation. Plos One. 7: e32038. PMID 22363792 DOI: 10.1371/journal.pone.0032038 |
0.611 |
|
| 2012 |
Guo Q, Zheng H, Justice NJ. Central CRF system perturbation in an Alzheimer's disease knockin mouse model. Neurobiology of Aging. 33: 2678-91. PMID 22336193 DOI: 10.1016/J.Neurobiolaging.2012.01.002 |
0.821 |
|
| 2012 |
Guo Q, Li H, Gaddam SS, Justice NJ, Robertson CS, Zheng H. Amyloid precursor protein revisited: neuron-specific expression and highly stable nature of soluble derivatives. The Journal of Biological Chemistry. 287: 2437-45. PMID 22144675 DOI: 10.1074/Jbc.M111.315051 |
0.831 |
|
| 2012 |
Guo Q, Wang Z, Li H, Wiese M, Zheng H. APP physiological and pathophysiological functions: insights from animal models. Cell Research. 22: 78-89. PMID 21769132 DOI: 10.1038/Cr.2011.116 |
0.831 |
|
| 2012 |
Wang Z, Yang L, Zheng H. Role of APP and Aβ in synaptic physiology. Current Alzheimer Research. 9: 217-26. PMID 21605029 DOI: 10.2174/156720512799361691 |
0.796 |
|
| 2012 |
Zheng H. Deciphering the role of APP in synaptic function Molecular Neurodegeneration. 7: L7. DOI: 10.1186/1750-1326-7-S1-L7 |
0.502 |
|
| 2011 |
Wang B, Harrison W, Overbeek PA, Zheng H. Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development. Development (Cambridge, England). 138: 4487-97. PMID 21937600 DOI: 10.1242/dev.067264 |
0.729 |
|
| 2011 |
Shim DJ, Yang L, Reed JG, Noebels JL, Chiao PJ, Zheng H. Disruption of the NF-κB/IκBα Autoinhibitory Loop Improves Cognitive Performance and Promotes Hyperexcitability of Hippocampal Neurons. Molecular Neurodegeneration. 6: 42. PMID 21663635 DOI: 10.1186/1750-1326-6-42 |
0.636 |
|
| 2011 |
Zheng H, Koo EH. Biology and pathophysiology of the amyloid precursor protein. Molecular Neurodegeneration. 6: 27. PMID 21527012 DOI: 10.1186/1750-1326-6-27 |
0.503 |
|
| 2011 |
Barbagallo AP, Wang Z, Zheng H, D'Adamio L. The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function. Plos One. 6: e18006. PMID 21445342 DOI: 10.1371/Journal.Pone.0018006 |
0.792 |
|
| 2011 |
Barbagallo AP, Wang Z, Zheng H, D'Adamio L. A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function. The Journal of Biological Chemistry. 286: 8717-21. PMID 21266574 DOI: 10.1074/Jbc.C111.219873 |
0.773 |
|
| 2010 |
Peethumnongsin E, Yang L, Kallhoff-Muñoz V, Hu L, Takashima A, Pautler RG, Zheng H. Convergence of presenilin- and tau-mediated pathways on axonal trafficking and neuronal function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13409-18. PMID 20926667 DOI: 10.1523/Jneurosci.1964-10.2010 |
0.83 |
|
| 2010 |
Wiese M, Antebi A, Zheng H. Intracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegans. Plos One. 5. PMID 20862215 DOI: 10.1371/journal.pone.0012790 |
0.665 |
|
| 2010 |
Li H, Wang B, Wang Z, Guo Q, Tabuchi K, Hammer RE, Südhof TC, Zheng H. Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP. Proceedings of the National Academy of Sciences of the United States of America. 107: 17362-7. PMID 20855613 DOI: 10.1073/Pnas.1012568107 |
0.826 |
|
| 2010 |
Smith KD, Peethumnongsin E, Lin H, Zheng H, Pautler RG. Increased Human Wildtype Tau Attenuates Axonal Transport Deficits Caused by Loss of APP in Mouse Models. Magnetic Resonance Insights. 4: 11-18. PMID 20798780 |
0.761 |
|
| 2010 |
Peng B, Ling J, Lee AJ, Wang Z, Chang Z, Jin W, Kang Y, Zhang R, Shim D, Wang H, Fleming JB, Zheng H, Sun SC, Chiao PJ. Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter. Proceedings of the National Academy of Sciences of the United States of America. 107: 15193-8. PMID 20696914 DOI: 10.1073/Pnas.1005533107 |
0.762 |
|
| 2010 |
Li H, Wang Z, Wang B, Guo Q, Dolios G, Tabuchi K, Hammer RE, Südhof TC, Wang R, Zheng H. Genetic dissection of the amyloid precursor protein in developmental function and amyloid pathogenesis. The Journal of Biological Chemistry. 285: 30598-605. PMID 20693289 DOI: 10.1074/Jbc.M110.137729 |
0.818 |
|
| 2010 |
Hernandez CM, Kayed R, Zheng H, Sweatt JD, Dineley KT. Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2442-53. PMID 20164328 DOI: 10.1523/Jneurosci.5038-09.2010 |
0.476 |
|
| 2010 |
Umeda T, Mori H, Zheng H, Tomiyama T. Regulation of cholesterol efflux by amyloid beta secretion. Journal of Neuroscience Research. 88: 1985-94. PMID 20155813 DOI: 10.1002/jnr.22360 |
0.332 |
|
| 2009 |
Yang L, Wang Z, Wang B, Justice NJ, Zheng H. Amyloid precursor protein regulates Cav1.2 L-type calcium channel levels and function to influence GABAergic short-term plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15660-8. PMID 20016080 DOI: 10.1523/JNEUROSCI.4104-09.2009 |
0.808 |
|
| 2009 |
Shelton CC, Zhu L, Chau D, Yang L, Wang R, Djaballah H, Zheng H, Li YM. Modulation of gamma-secretase specificity using small molecule allosteric inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 106: 20228-33. PMID 19906985 DOI: 10.1073/Pnas.0910757106 |
0.455 |
|
| 2009 |
Wang Z, Wang B, Yang L, Guo Q, Aithmitti N, Songyang Z, Zheng H. Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10788-801. PMID 19726636 DOI: 10.1523/Jneurosci.2132-09.2009 |
0.816 |
|
| 2009 |
Placanica L, Tarassishin L, Yang G, Peethumnongsin E, Kim SH, Zheng H, Sisodia SS, Li YM. Pen2 and presenilin-1 modulate the dynamic equilibrium of presenilin-1 and presenilin-2 gamma-secretase complexes. The Journal of Biological Chemistry. 284: 2967-77. PMID 19036728 DOI: 10.1074/Jbc.M807269200 |
0.8 |
|
| 2009 |
Zheng H. Deciphering the role of APP in synaptic regulation Alzheimers & Dementia. 5: 68. DOI: 10.1016/J.Jalz.2009.05.148 |
0.393 |
|
| 2008 |
Kallhoff-Munoz V, Hu L, Chen X, Pautler RG, Zheng H. Genetic dissection of gamma-secretase-dependent and -independent functions of presenilin in regulating neuronal cell cycle and cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11421-31. PMID 18971484 DOI: 10.1523/Jneurosci.2873-08.2008 |
0.426 |
|
| 2008 |
Wiese ME, Antebi A, Zheng H. P1-091: Investigation of APP pathophysiology in C. elegans Alzheimer's & Dementia. 4: T233-T233. DOI: 10.1016/j.jalz.2008.05.677 |
0.491 |
|
| 2008 |
Zheng H. S4-01-03: Effects of FAD-linked mutations on physiology and pathology Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.474 |
0.311 |
|
| 2008 |
Kallhoff-Munoz V, Hu L, Pautler R, Zheng H. P4-196: Presenilin in neuronal survival and neurodegeneration Alzheimer's & Dementia. 4: T729-T729. DOI: 10.1016/J.Jalz.2008.05.2263 |
0.415 |
|
| 2007 |
Yang L, Wang B, Long C, Wu G, Zheng H. Increased asynchronous release and aberrant calcium channel activation in amyloid precursor protein deficient neuromuscular synapses Neuroscience. 149: 768-778. PMID 17919826 DOI: 10.1016/j.neuroscience.2007.08.025 |
0.774 |
|
| 2007 |
Repetto E, Yoon IS, Zheng H, Kang DE. Presenilin 1 regulates epidermal growth factor receptor turnover and signaling in the endosomal-lysosomal pathway. The Journal of Biological Chemistry. 282: 31504-16. PMID 17716970 DOI: 10.1074/Jbc.M704273200 |
0.368 |
|
| 2007 |
Wang B, Yang L, Wang Z, Zheng H. Amyolid precursor protein mediates presynaptic localization and activity of the high-affinity choline transporter. Proceedings of the National Academy of Sciences of the United States of America. 104: 14140-5. PMID 17709753 DOI: 10.1073/pnas.0704070104 |
0.835 |
|
| 2007 |
Smith KD, Kallhoff V, Zheng H, Pautler RG. In vivo axonal transport rates decrease in a mouse model of Alzheimer's disease. Neuroimage. 35: 1401-8. PMID 17369054 DOI: 10.1016/J.Neuroimage.2007.01.046 |
0.443 |
|
| 2007 |
Kallhoff V, Peethumnongsin E, Zheng H. Lack of alpha-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease. Molecular Neurodegeneration. 2: 6. PMID 17367539 DOI: 10.1186/1750-1326-2-6 |
0.793 |
|
| 2006 |
Zheng H, Koo EH. The amyloid precursor protein: beyond amyloid. Molecular Neurodegeneration. 1: 5. PMID 16930452 DOI: 10.1186/1750-1326-1-5 |
0.47 |
|
| 2006 |
Deng Y, Tarassishin L, Kallhoff V, Peethumnongsin E, Wu L, Li YM, Zheng H. Deletion of presenilin 1 hydrophilic loop sequence leads to impaired gamma-secretase activity and exacerbated amyloid pathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3845-54. PMID 16597739 DOI: 10.1523/Jneurosci.5384-05.2006 |
0.832 |
|
| 2006 |
Wang R, Wang B, He W, Zheng H. Wild-type presenilin 1 protects against Alzheimer disease mutation-induced amyloid pathology. The Journal of Biological Chemistry. 281: 15330-6. PMID 16574645 DOI: 10.1074/jbc.M512574200 |
0.799 |
|
| 2006 |
Cai D, Zhong M, Wang R, Netzer WJ, Shields D, Zheng H, Sisodia SS, Foster DA, Gorelick FS, Xu H, Greengard P. Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons. Proceedings of the National Academy of Sciences of the United States of America. 103: 1936-40. PMID 16449385 DOI: 10.1073/Pnas.0510710103 |
0.477 |
|
| 2006 |
Wang B, Zheng H. AbstractPoster presentation: Sunday posterP1-395: The function of amyloid precursor protein (APP) in cholinergic system Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.773 |
0.467 |
|
| 2005 |
Wang R, Tang P, Wang P, Boissy RE, Zheng H. Regulation of tyrosinase trafficking and processing by presenilins: partial loss of function by familial Alzheimer's disease mutation. Proceedings of the National Academy of Sciences of the United States of America. 103: 353-8. PMID 16384915 DOI: 10.1073/PNAS.0509822102 |
0.467 |
|
| 2005 |
Han P, Dou F, Li F, Zhang X, Zhang YW, Zheng H, Lipton SA, Xu H, Liao FF. Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11542-52. PMID 16354912 DOI: 10.1523/Jneurosci.3831-05.2005 |
0.497 |
|
| 2005 |
Yang G, Gong YD, Gong K, Jiang WL, Kwon E, Wang P, Zheng H, Zhang XF, Gan WB, Zhao NM. Reduced synaptic vesicle density and active zone size in mice lacking amyloid precursor protein (APP) and APP-like protein 2. Neuroscience Letters. 384: 66-71. PMID 15919150 DOI: 10.1016/J.Neulet.2005.04.040 |
0.512 |
|
| 2005 |
Wang P, Yang G, Mosier DR, Chang P, Zaidi T, Gong YD, Zhao NM, Dominguez B, Lee KF, Gan WB, Zheng H. Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1219-25. PMID 15689559 DOI: 10.1523/Jneurosci.4660-04.2005 |
0.535 |
|
| 2004 |
Esselens C, Oorschot V, Baert V, Raemaekers T, Spittaels K, Serneels L, Zheng H, Saftig P, De Strooper B, Klumperman J, Annaert W. Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway. The Journal of Cell Biology. 166: 1041-54. PMID 15452145 DOI: 10.1083/Jcb.200406060 |
0.426 |
|
| 2004 |
Wang R, Dineley KT, Sweatt JD, Zheng H. Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis. Neuroscience. 126: 305-12. PMID 15207348 DOI: 10.1016/j.neuroscience.2004.03.048 |
0.449 |
|
| 2004 |
Qyang Y, Chambers SM, Wang P, Xia X, Chen X, Goodell MA, Zheng H. Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage. Biochemistry. 43: 5352-9. PMID 15122901 DOI: 10.1021/Bi049826U |
0.457 |
|
| 2003 |
Wang P, Pereira FA, Beasley D, Zheng H. Presenilins are required for the formation of comma- and S-shaped bodies during nephrogenesis Development. 130: 5019-5029. PMID 12930775 DOI: 10.1242/Dev.00682 |
0.349 |
|
| 2003 |
Cai D, Leem JY, Greenfield JP, Wang P, Kim BS, Wang R, Lopes KO, Kim SH, Zheng H, Greengard P, Sisodia SS, Thinakaran G, Xu H. Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein. The Journal of Biological Chemistry. 278: 3446-54. PMID 12435726 DOI: 10.1074/Jbc.M209065200 |
0.407 |
|
| 2002 |
Kang DE, Soriano S, Xia X, Eberhart CG, De Strooper B, Zheng H, Koo EH. Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis. Cell. 110: 751-62. PMID 12297048 DOI: 10.1016/S0092-8674(02)00970-4 |
0.323 |
|
| 2002 |
Xia X, Wang P, Sun X, Soriano S, Shum WK, Yamaguchi H, Trumbauer ME, Takashima A, Koo EH, Zheng H. The aspartate-257 of presenilin 1 is indispensable for mouse development and production of beta-amyloid peptides through beta-catenin-independent mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 99: 8760-5. PMID 12070348 DOI: 10.1073/Pnas.132045399 |
0.441 |
|
| 2002 |
Moehlmann T, Winkler E, Xia X, Edbauer D, Murrell J, Capell A, Kaether C, Zheng H, Ghetti B, Haass C, Steiner H. Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production. Proceedings of the National Academy of Sciences of the United States of America. 99: 8025-30. PMID 12048239 DOI: 10.1073/Pnas.112686799 |
0.491 |
|
| 2002 |
Dineley KT, Xia X, Bui D, Sweatt JD, Zheng H. Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins. The Journal of Biological Chemistry. 277: 22768-80. PMID 11912199 DOI: 10.1074/jbc.M200164200 |
0.454 |
|
| 2002 |
Morton RA, Kuenzi FM, Fitzjohn SM, Rosahl TW, Smith D, Zheng H, Shearman M, Collingridge GL, Seabrook GR. Impairment in hippocampal long-term potentiation in mice under-expressing the Alzheimer's disease related gene presenilin-1. Neuroscience Letters. 319: 37-40. PMID 11814648 DOI: 10.1016/S0304-3940(01)02512-5 |
0.42 |
|
| 2002 |
Zheng H, Xu H, Uljon SN, Gross R, Hardy K, Gaynor J, Lafrancois J, Simpkins J, Refolo LM, Petanceska S, Wang R, Duff K. Modulation of A(beta) peptides by estrogen in mouse models. Journal of Neurochemistry. 80: 191-6. PMID 11796757 DOI: 10.1046/J.0022-3042.2001.00690.X |
0.396 |
|
| 2001 |
Xia X, Qian S, Soriano S, Wu Y, Fletcher AM, Wang XJ, Koo EH, Wu X, Zheng H. Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 98: 10863-8. PMID 11517342 DOI: 10.1073/Pnas.191284198 |
0.355 |
|
| 2001 |
Cherny RA, Atwood CS, Xilinas ME, Gray DN, Jones WD, McLean CA, Barnham KJ, Volitakis I, Fraser FW, Kim Y, Huang X, Goldstein LE, Moir RD, Lim JT, Beyreuther K, ... Zheng H, et al. Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron. 30: 665-76. PMID 11430801 DOI: 10.1016/S0896-6273(01)00317-8 |
0.454 |
|
| 2001 |
Soriano S, Kang DE, Fu M, Pestell R, Chevallier N, Zheng H, Koo EH. Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing. The Journal of Cell Biology. 152: 785-94. PMID 11266469 DOI: 10.1083/Jcb.152.4.785 |
0.363 |
|
| 1998 |
White AR, Zheng H, Galatis D, Maher F, Hesse L, Multhaup G, Beyreuther K, Masters CL, Cappai R. Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6207-17. PMID 9698314 |
0.385 |
|
| 1998 |
Qian S, Jiang P, Guan XM, Singh G, Trumbauer ME, Yu H, Chen HY, Van de Ploeg LH, Zheng H. Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression. Neuron. 20: 611-7. PMID 9539133 DOI: 10.1016/S0896-6273(00)80999-X |
0.353 |
|
| 1995 |
Zheng H, Jiang M, Trumbauer ME, Sirinathsinghji DJ, Hopkins R, Smith DW, Heavens RP, Dawson GR, Boyce S, Conner MW, Stevens KA, Slunt HH, Sisoda SS, Chen HY, Van der Ploeg LH. beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity. Cell. 81: 525-31. PMID 7758106 DOI: 10.1016/0092-8674(95)90073-X |
0.409 |
|
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