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Yam B. Poudel, Ph D - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Organic chemistry
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15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Poudel YB, Rao C, Kotapati S, Deshpande M, Thevanayagam L, Pan C, Cardarelli J, Chowdari N, Kaspady M, Samikannu R, Kuppusamy P, Saravanakumar P, Arunachalam PN, Deshpande S, Rangan V, et al. Design, synthesis and biological evaluation of phenol-linked uncialamycin antibody-drug conjugates. Bioorganic & Medicinal Chemistry Letters. 126782. PMID 31767265 DOI: 10.1016/J.Bmcl.2019.126782  0.329
2016 Nicolaou KC, Wang Y, Lu M, Mandal D, Pattanayak MR, Yu R, Shah AA, Chen JS, Zhang H, Crawford JJ, Pasunoori L, Poudel YB, Chowdari NS, Pan C, Nazeer A, et al. Streamlined Total Synthesis of Uncialamycin and Its Application to the Synthesis of Designed Analogues for Biological Investigations. Journal of the American Chemical Society. PMID 27266267 DOI: 10.1021/Jacs.6B04339  0.473
2015 Lee K, Poudel YB, Glinkerman CM, Boger DL. Total synthesis of dihydrolysergic acid and dihydrolysergol: development of a divergent synthetic strategy applicable to rapid assembly of D-ring analogs. Tetrahedron. 71: 5897-5905. PMID 26273113 DOI: 10.1016/J.Tet.2015.05.093  0.788
2015 Lee K, Poudel YB, Glinkerman CM, Boger DL. Total synthesis of dihydrolysergic acid and dihydrolysergol: Development of a divergent synthetic strategy applicable to rapid assembly of D-ring analogs Tetrahedron. DOI: 10.1016/j.tet.2015.05.093  0.489
2014 Kraft MB, Poudel YB, Kedei N, Lewin NE, Peach ML, Blumberg PM, Keck GE. Synthesis of a des-B-ring bryostatin analogue leads to an unexpected ring expansion of the bryolactone core. Journal of the American Chemical Society. 136: 13202-8. PMID 25207434 DOI: 10.1021/Ja5078188  0.793
2013 Kedei N, Lewin NE, Géczy T, Selezneva J, Braun DC, Chen J, Herrmann MA, Heldman MR, Lim L, Mannan P, Garfield SH, Poudel YB, Cummins TJ, Rudra A, Blumberg PM, et al. Biological profile of the less lipophilic and synthetically more accessible bryostatin 7 closely resembles that of bryostatin 1. Acs Chemical Biology. 8: 767-77. PMID 23369356 DOI: 10.1021/Cb300671S  0.688
2013 Breazzano SP, Poudel YB, Boger DL. A Pd(0)-mediated indole (macro)cyclization reaction. Journal of the American Chemical Society. 135: 1600-6. PMID 23298368 DOI: 10.1021/Ja3121394  0.775
2013 Kedei N, Telek A, Michalowski AM, Kraft MB, Li W, Poudel YB, Rudra A, Petersen ME, Keck GE, Blumberg PM. Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogs in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action. Biochemical Pharmacology. 85: 313-24. PMID 23146662 DOI: 10.1016/J.Bcp.2012.10.028  0.719
2012 Keck GE, Poudel YB, Rudra A, Stephens JC, Kedei N, Lewin NE, Blumberg PM. Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity. Bioorganic & Medicinal Chemistry Letters. 22: 4084-8. PMID 22579485 DOI: 10.1016/J.Bmcl.2012.04.073  0.731
2012 Kedei N, Telek A, Michalowski AM, Kraft MB, Li W, Poudel YB, Rudra A, Petersen ME, Keck GE, Blumberg PM. Abstract 3815: Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogues in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action Cancer Research. 72: 3815-3815. DOI: 10.1158/1538-7445.Am2012-3815  0.721
2011 Keck GE, Poudel YB, Cummins TJ, Rudra A, Covel JA. Total synthesis of bryostatin 1. Journal of the American Chemical Society. 133: 744-7. PMID 21175177 DOI: 10.1021/Ja110198Y  0.791
2011 Keck GE, Poudel YB, Cummins TJ, Rudra A, Covel JA. Synthesis of Bryostatin 1 Synfacts. 2011: 464-464. DOI: 10.1055/S-0030-1259787  0.738
2010 Keck GE, Poudel YB, Rudra A, Stephens JC, Kedei N, Lewin NE, Peach ML, Blumberg PM. Molecular modeling, total synthesis, and biological evaluations of C9-deoxy bryostatin 1. Angewandte Chemie (International Ed. in English). 49: 4580-4. PMID 20491108 DOI: 10.1002/Anie.201001200  0.668
2009 Keck GE, Poudel YB, Welch DS, Kraft MB, Truong AP, Stephens JC, Kedei N, Lewin NE, Blumberg PM. Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol esters. Organic Letters. 11: 593-6. PMID 19113896 DOI: 10.1021/Ol8027253  0.724
2006 Keck GE, Welch DS, Poudel YB. Synthetic Studies Toward Bryostatin 1: Preparation of a C(1)-C(16) Fragment by Pyran Annulation. Tetrahedron Letters. 47: 8267-8270. PMID 17404602 DOI: 10.1016/J.Tetlet.2006.09.094  0.78
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