Takeshi Sakurai - Publications

Affiliations: 
Kanazawa University, Kanazawa-shi, Ishikawa-ken, Japan 
Area:
sleep, feeding, neuropeptide

143 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Nakai A, Fujiyama T, Nagata N, Kashiwagi M, Ikkyu A, Takagi M, Tatsuzawa C, Tanaka K, Kakizaki M, Kanuka M, Kawano T, Mizuno S, Sugiyama F, Takahashi S, Funato H, ... Sakurai T, et al. Sleep Architecture in Mice Is Shaped by the Transcription Factor AP-2β. Genetics. PMID 32878901 DOI: 10.1534/Genetics.120.303435  0.319
2020 Soya S, Sakurai T. Evolution of Orexin Neuropeptide System: Structure and Function Frontiers in Neuroscience. 14: 691. PMID 32754010 DOI: 10.3389/Fnins.2020.00691  0.356
2019 Bassetti CLA, Adamantidis A, Burdakov D, Han F, Gay S, Kallweit U, Khatami R, Koning F, Kornum BR, Lammers GJ, Liblau RS, Luppi PH, Mayer G, Pollmächer T, Sakurai T, et al. Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment. Nature Reviews. Neurology. PMID 31324898 DOI: 10.1038/S41582-019-0226-9  0.306
2019 Kodani S, Soya S, Sakurai T. Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice. Journal of Visualized Experiments. PMID 31282883 DOI: 10.3791/58613  0.376
2019 Zhang T, Yanagida J, Kamii H, Wada S, Domoto M, Sasase H, Deyama S, Takarada T, Hinoi E, Sakimura K, Yamanaka A, Maejima T, Mieda M, Sakurai T, Nishitani N, et al. Glutamatergic neurons in the medial prefrontal cortex mediate the formation and retrieval of cocaine-associated memories in mice. Addiction Biology. PMID 30734456 DOI: 10.1111/Adb.12723  0.309
2019 Koyanagi I, Akers KG, Vergara P, Srinivasan S, Sakurai T, Sakaguchi M. Memory consolidation during sleep and adult hippocampal neurogenesis. Neural Regeneration Research. 14: 20-23. PMID 30531064 DOI: 10.4103/1673-5374.243695  0.306
2019 Sakaguchi M, Koyanagi I, Carrier-Ruiz A, Vergara P, Srinivasan S, Sugaya Y, Kasuya M, Yu T, Vogt K, Muratani M, Ohnishi T, Singh S, Teixeira CM, Chérasse Y, Naoi T, ... ... Sakurai T, et al. Function of adult-born neurons in maturation of fear memory engram during sleep Ibro Reports. 6: S23-S24. DOI: 10.1016/J.Ibror.2019.07.062  0.309
2018 Saito YC, Tsujino N, Abe M, Yamazaki M, Sakimura K, Sakurai T. Serotonergic Input to Orexin Neurons Plays a Role in Maintaining Wakefulness and REM Sleep Architecture. Frontiers in Neuroscience. 12: 892. PMID 30555297 DOI: 10.3389/Fnins.2018.00892  0.38
2018 Soya S, Sakurai T. Orexin as a modulator of fear-related behavior: Hypothalamic control of noradrenaline circuit. Brain Research. PMID 30481504 DOI: 10.1016/J.Brainres.2018.11.032  0.339
2018 Takata Y, Oishi Y, Zhou XZ, Hasegawa E, Takahashi K, Cherasse Y, Sakurai T, Lazarus M. Sleep and wakefulness are controlled by ventral medial midbrain/pons GABAergic neurons in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30282729 DOI: 10.1523/Jneurosci.0598-18.2018  0.382
2018 Saito Y, Maejima T, Nishitani M, Hasegawa E, Yanagawa Y, Mieda M, Sakurai T. Monoamines Inhibit GABAergic Neurons in Ventrolateral Preoptic Area that make Direct Synaptic Connections to Hypothalamic Arousal Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29915137 DOI: 10.1523/Jneurosci.2835-17.2018  0.355
2018 Sumitomo A, Yukitake H, Hirai K, Horike K, Ueta K, Chung Y, Warabi E, Yanagawa T, Kitaoka S, Furuyashiki T, Narumiya S, Hirano T, Niwa M, Sibille E, Hikida T, ... Sakurai T, et al. Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons. Human Molecular Genetics. PMID 29893844 DOI: 10.1093/Hmg/Ddy219  0.373
2018 Wang Y, Cao L, Lee CY, Matsuo T, Wu K, Asher G, Tang L, Saitoh T, Russell J, Klewe-Nebenius D, Wang L, Soya S, Hasegawa E, Chérasse Y, Zhou J, ... ... Sakurai T, et al. Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors. Nature Communications. 9: 2041. PMID 29795268 DOI: 10.1038/S41467-018-04324-3  0.3
2018 Akers KG, Chérasse Y, Fujita Y, Srinivasan S, Sakurai T, Sakaguchi M. Regulatory Influence of Sleep and Epigenetics on Adult Hippocampal Neurogenesis and Cognitive and Emotional Function. Stem Cells (Dayton, Ohio). PMID 29484772 DOI: 10.1002/Stem.2815  0.327
2017 Soya S, Takahashi TM, McHugh TJ, Maejima T, Herlitze S, Abe M, Sakimura K, Sakurai T. Orexin modulates behavioral fear expression through the locus coeruleus. Nature Communications. 8: 1606. PMID 29151577 DOI: 10.1038/S41467-017-01782-Z  0.352
2017 Thompson MD, Sakurai T, Rainero I, Maj MC, Kukkonen JP. Orexin Receptor Multimerization versus Functional Interactions: Neuropharmacological Implications for Opioid and Cannabinoid Signalling and Pharmacogenetics. Pharmaceuticals (Basel, Switzerland). 10. PMID 28991183 DOI: 10.3390/Ph10040079  0.328
2017 Hara C, Morishita K, Takayanagi-Kiya S, Mikami A, Uchino K, Sakurai T, Kanzaki R, Sezutsu H, Iwami M, Kiya T. Refinement of ectopic protein expression through the GAL4/UAS system in Bombyx mori: application to behavioral and developmental studies. Scientific Reports. 7: 11795. PMID 28924263 DOI: 10.1038/S41598-017-12102-2  0.31
2017 Kodani S, Soya S, Sakurai T. Excitation of GABAergic Neurons in the Bed Nucleus of the Stria Terminalis Triggers Immediate Transition from Non-Rapid Eye Movement Sleep to Wakefulness in Mice The Journal of Neuroscience. 37: 7164-7176. PMID 28642284 DOI: 10.1523/Jneurosci.0245-17.2017  0.363
2017 Irukayama-Tomobe Y, Ogawa Y, Tominaga H, Ishikawa Y, Hosokawa N, Ambai S, Kawabe Y, Uchida S, Nakajima R, Saitoh T, Kanda T, Vogt K, Sakurai T, Nagase H, Yanagisawa M. Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models. Proceedings of the National Academy of Sciences of the United States of America. PMID 28507129 DOI: 10.1073/Pnas.1700499114  0.383
2017 Hasegawa E, Maejima T, Yoshida T, Masseck OA, Herlitze S, Yoshioka M, Sakurai T, Mieda M. Serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396432 DOI: 10.1016/J.Sleep.2017.11.372  0.37
2017 Mieda M, Hasegawa E, Kessaris N, Sakurai T. Fine-Tuning Circadian Rhythms: The Importance of Bmal1 Expression in the Ventral Forebrain. Frontiers in Neuroscience. 11: 55. PMID 28232786 DOI: 10.3389/Fnins.2017.00055  0.309
2016 Okamoto K, Yamasaki M, Takao K, Soya S, Iwasaki M, Sasaki K, Magoori K, Sakakibara I, Miyakawa T, Mieda M, Watanabe M, Sakai J, Yanagisawa M, Sakurai T. QRFP-Deficient Mice Are Hypophagic, Lean, Hypoactive and Exhibit Increased Anxiety-Like Behavior. Plos One. 11: e0164716. PMID 27835635 DOI: 10.1371/Journal.Pone.0164716  0.358
2016 Mieda M, Okamoto H, Sakurai T. Manipulating the Cellular Circadian Period of Arginine Vasopressin Neurons Alters the Behavioral Circadian Period. Current Biology : Cb. PMID 27568590 DOI: 10.1016/J.Cub.2016.07.022  0.357
2016 Motoike T, Long JM, Tanaka H, Sinton CM, Skach A, Williams SC, Hammer RE, Sakurai T, Yanagisawa M. Mesolimbic neuropeptide W coordinates stress responses under novel environments. Proceedings of the National Academy of Sciences of the United States of America. PMID 27140610 DOI: 10.1073/Pnas.1518658113  0.36
2015 Abbas MG, Shoji H, Soya S, Hondo M, Miyakawa T, Sakurai T. Comprehensive Behavioral Analysis of Male Ox1r (-/-) Mice Showed Implication of Orexin Receptor-1 in Mood, Anxiety, and Social Behavior. Frontiers in Behavioral Neuroscience. 9: 324. PMID 26696848 DOI: 10.3389/Fnbeh.2015.00324  0.348
2015 Tanaka S, Toyoda H, Honda Y, Seki Y, Sakurai T, Honda K, Kodama T. Hypocretin/orexin prevents recovery from sickness. Biomedical Reports. 3: 648-650. PMID 26405539 DOI: 10.3892/Br.2015.491  0.333
2015 Mieda M, Ono D, Hasegawa E, Okamoto H, Honma K, Honma S, Sakurai T. Cellular clocks in AVP neurons of the SCN are critical for interneuronal coupling regulating circadian behavior rhythm. Neuron. 85: 1103-16. PMID 25741730 DOI: 10.1016/J.Neuron.2015.02.005  0.361
2015 Sakurai T. [Central regulation of feeding behavior]. Brain and Nerve = Shinkei Kenkyū No Shinpo. 67: 131-9. PMID 25681359 DOI: 10.11477/Mf.1416200106  0.308
2014 Charles R, Sakurai T, Takahashi N, Elder GA, Gama Sosa MA, Young LJ, Buxbaum JD. Introduction of the human AVPR1A gene substantially alters brain receptor expression patterns and enhances aspects of social behavior in transgenic mice. Disease Models & Mechanisms. 7: 1013-22. PMID 24924430 DOI: 10.1242/Dmm.017053  0.305
2014 Tabuchi S, Tsunematsu T, Black SW, Tominaga M, Maruyama M, Takagi K, Minokoshi Y, Sakurai T, Kilduff TS, Yamanaka A. Conditional ablation of orexin/hypocretin neurons: a new mouse model for the study of narcolepsy and orexin system function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 6495-509. PMID 24806676 DOI: 10.1523/Jneurosci.0073-14.2014  0.384
2014 Schöne C, Apergis-Schoute J, Sakurai T, Adamantidis A, Burdakov D. Coreleased orexin and glutamate evoke nonredundant spike outputs and computations in histamine neurons. Cell Reports. 7: 697-704. PMID 24767990 DOI: 10.1016/J.Celrep.2014.03.055  0.33
2014 Etori K, Saito YC, Tsujino N, Sakurai T. Effects of a newly developed potent orexin-2 receptor-selective antagonist, compound 1 m, on sleep/wakefulness states in mice. Frontiers in Neuroscience. 8: 8. PMID 24550770 DOI: 10.3389/Fnins.2014.00008  0.354
2014 Hasegawa E, Yanagisawa M, Sakurai T, Mieda M. Orexin neurons suppress narcolepsy via 2 distinct efferent pathways. The Journal of Clinical Investigation. 124: 604-16. PMID 24382351 DOI: 10.1172/Jci71017  0.401
2013 Saito YC, Tsujino N, Hasegawa E, Akashi K, Abe M, Mieda M, Sakimura K, Sakurai T. GABAergic neurons in the preoptic area send direct inhibitory projections to orexin neurons. Frontiers in Neural Circuits. 7: 192. PMID 24348342 DOI: 10.3389/Fncir.2013.00192  0.372
2013 Tabuchi M, Sakurai T, Mitsuno H, Namiki S, Minegishi R, Shiotsuki T, Uchino K, Sezutsu H, Tamura T, Haupt SS, Nakatani K, Kanzaki R. Pheromone responsiveness threshold depends on temporal integration by antennal lobe projection neurons. Proceedings of the National Academy of Sciences of the United States of America. 110: 15455-60. PMID 24006366 DOI: 10.1073/Pnas.1313707110  0.309
2013 Soya S, Shoji H, Hasegawa E, Hondo M, Miyakawa T, Yanagisawa M, Mieda M, Sakurai T. Orexin receptor-1 in the locus coeruleus plays an important role in cue-dependent fear memory consolidation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14549-57. PMID 24005305 DOI: 10.1523/Jneurosci.1130-13.2013  0.352
2013 Takahashi Y, Zhang W, Sameshima K, Kuroki C, Matsumoto A, Sunanaga J, Kono Y, Sakurai T, Kanmura Y, Kuwaki T. Orexin neurons are indispensable for prostaglandin E2-induced fever and defence against environmental cooling in mice. The Journal of Physiology. 591: 5623-43. PMID 23959674 DOI: 10.1113/Jphysiol.2013.261271  0.35
2013 Tsujino N, Tsunematsu T, Uchigashima M, Konno K, Yamanaka A, Kobayashi K, Watanabe M, Koyama Y, Sakurai T. Chronic alterations in monoaminergic cells in the locus coeruleus in orexin neuron-ablated narcoleptic mice. Plos One. 8: e70012. PMID 23922890 DOI: 10.1371/Journal.Pone.0070012  0.385
2013 Mieda M, Tsujino N, Sakurai T. Differential roles of orexin receptors in the regulation of sleep/wakefulness. Frontiers in Endocrinology. 4: 57. PMID 23730297 DOI: 10.3389/Fendo.2013.00057  0.326
2013 Furutani N, Hondo M, Kageyama H, Tsujino N, Mieda M, Yanagisawa M, Shioda S, Sakurai T. Neurotensin co-expressed in orexin-producing neurons in the lateral hypothalamus plays an important role in regulation of sleep/wakefulness states. Plos One. 8: e62391. PMID 23620827 DOI: 10.1371/Journal.Pone.0062391  0.394
2013 Tsujino N, Sakurai T. Role of orexin in modulating arousal, feeding, and motivation. Frontiers in Behavioral Neuroscience. 7: 28. PMID 23616752 DOI: 10.3389/Fnbeh.2013.00028  0.376
2013 Yang L, Zou B, Xiong X, Pascual C, Xie J, Malik A, Xie J, Sakurai T, Xie XS. Hypocretin/orexin neurons contribute to hippocampus-dependent social memory and synaptic plasticity in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5275-84. PMID 23516292 DOI: 10.1523/Jneurosci.3200-12.2013  0.309
2013 Mieda M, Sakurai T. Orexin (hypocretin) receptor agonists and antagonists for treatment of sleep disorders. Rationale for development and current status. Cns Drugs. 27: 83-90. PMID 23359095 DOI: 10.1007/S40263-012-0036-8  0.341
2013 Xiong X, White RE, Xu L, Yang L, Sun X, Zou B, Pascual C, Sakurai T, Giffard RG, Xie XS. Mitigation of murine focal cerebral ischemia by the hypocretin/orexin system is associated with reduced inflammation. Stroke; a Journal of Cerebral Circulation. 44: 764-70. PMID 23349191 DOI: 10.1161/Strokeaha.112.681700  0.306
2013 Kanda N, Saito Y, Abe M, Sakimura K, Yanagisawa M, Sakurai T. 2P233 Functional connection between GABAergic neurons in the preoptic area and orexinergic neurons in the hypothalamus(16. Neuronal Circuit & Information processing,Poster) Seibutsu Butsuri. 53. DOI: 10.2142/Biophys.53.S197_4  0.325
2013 Saito Y, Tsujino N, Mieda M, Abe M, Sakimura K, Sakurai T. Gabaergic transmission by POA neurons to orexin neurons Sleep Medicine. 14. DOI: 10.1016/J.Sleep.2013.11.617  0.374
2013 Hasegawa E, Yanagisawa M, Roth B, Sakurai T, Mieda M. Restoration of orexin signaling in the dorsal raphe and locus coeruleus differntially ameliorate symptoms of narcoleptic mice Sleep Medicine. 14. DOI: 10.1016/J.Sleep.2013.11.342  0.388
2013 Etori K, Saito Y, Tsujino N, Sakurai T. Effects of a newly developed orexin-2 receptor-selective antagonist on the sleep/wake states in mice Sleep Medicine. 14. DOI: 10.1016/J.Sleep.2013.11.261  0.31
2012 Schöne C, Cao ZF, Apergis-Schoute J, Adamantidis A, Sakurai T, Burdakov D. Optogenetic probing of fast glutamatergic transmission from hypocretin/orexin to histamine neurons in situ. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 12437-43. PMID 22956835 DOI: 10.1523/Jneurosci.0706-12.2012  0.362
2012 Bozdagi O, Sakurai T, Dorr N, Pilorge M, Takahashi N, Buxbaum JD. Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice. Plos One. 7: e42422. PMID 22900020 DOI: 10.1371/Journal.Pone.0042422  0.3
2012 Mieda M, Sakurai T. Overview of orexin/hypocretin system Progress in Brain Research. 198: 5-14. PMID 22813966 DOI: 10.1016/B978-0-444-59489-1.00002-1  0.317
2012 Tanada N, Sakurai T, Mitsuno H, Bakkum DJ, Kanzaki R, Takahashi H. Dissociated neuronal culture expressing ionotropic odorant receptors as a hybrid odorant biosensor--proof-of-concept study. The Analyst. 137: 3452-8. PMID 22717461 DOI: 10.1039/C2An35058K  0.311
2012 Takahashi H, Sakurai T, Sakai H, Bakkum DJ, Suzurikawa J, Kanzaki R. Light-addressed single-neuron stimulation in dissociated neuronal cultures with sparse expression of ChR2. Bio Systems. 107: 106-12. PMID 22019848 DOI: 10.1016/J.Biosystems.2011.10.002  0.339
2011 Hondo M, Furutani N, Yamasaki M, Watanabe M, Sakurai T. Orexin neurons receive glycinergic innervations Plos One. 6. PMID 21949857 DOI: 10.1371/Journal.Pone.0025076  0.389
2011 Sakurai T, Mitsuno H, Haupt SS, Uchino K, Yokohari F, Nishioka T, Kobayashi I, Sezutsu H, Tamura T, Kanzaki R. A single sex pheromone receptor determines chemical response specificity of sexual behavior in the silkmoth Bombyx mori. Plos Genetics. 7: e1002115. PMID 21738481 DOI: 10.1371/Journal.Pgen.1002115  0.305
2011 Sasaki K, Suzuki M, Mieda M, Tsujino N, Roth B, Sakurai T. Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice. Plos One. 6. PMID 21647372 DOI: 10.1371/Journal.Pone.0020360  0.379
2011 Sakurai T, Mieda M. Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousal Trends in Pharmacological Sciences. 32: 451-462. PMID 21565412 DOI: 10.1016/J.Tips.2011.03.007  0.333
2011 Mieda M, Hasegawa E, Kisanuki YY, Sinton CM, Yanagisawa M, Sakurai T. Differential Roles of Orexin Receptor-1 and -2 in the Regulation of Non-REM and REM Sleep The Journal of Neuroscience. 31: 6518-6526. PMID 21525292 DOI: 10.1523/Jneurosci.6506-10.2011  0.365
2011 Liu M, Blanco-Centurion C, Konadhode R, Begum S, Pelluru D, Gerashchenko D, Sakurai T, Yanagisawa M, van den Pol AN, Shiromani PJ. Orexin gene transfer into zona incerta neurons suppresses muscle paralysis in narcoleptic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6028-40. PMID 21508228 DOI: 10.1523/Jneurosci.6069-10.2011  0.372
2011 Nagata-Kuroiwa R, Furutani N, Hara J, Hondo M, Ishii M, Abe T, Mieda M, Tsujino N, Motoike T, Yanagawa Y, Kuwaki T, Yamamoto M, Yanagisawa M, Sakurai T. Critical role of neuropeptides B/W receptor 1 signaling in social behavior and fear memory. Plos One. 6: e16972. PMID 21390312 DOI: 10.1016/J.Neures.2011.07.1693  0.323
2011 Willie JT, Takahira H, Shibahara M, Hara J, Nomiyama M, Yanagisawa M, Sakurai T. Ectopic overexpression of orexin alters sleep/wakefulness states and muscle tone regulation during REM sleep in mice. Journal of Molecular Neuroscience : Mn. 43: 155-61. PMID 20711757 DOI: 10.1007/S12031-010-9437-7  0.31
2011 Hara J, Sakurai T. Interaction between sleep mechanisms and orexin neurons Sleep and Biological Rhythms. 9: 38-43. DOI: 10.1111/J.1479-8425.2010.00466.X  0.341
2011 Sasaki K, Suzuki M, Mieda M, Tsujino N, Roth B, Sakurai T. Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.741  0.351
2011 Tsujino N, Tsunematsu T, Yamanaka A, Koyama Y, Sakurai T. Alterations in noradrenergic neurons in orexin neuron-deficient mice Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.735  0.349
2011 Hondo M, Furutani N, Yamasaki M, Watanabe M, Sakurai T. Glycinergic regulation of orexin neurons Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.734  0.337
2011 Saito Y, Tsujino N, Mieda M, Sakimura K, Sakurai T. Functional and histological interaction between preoptic area GABAergic neurons and orexin neurons Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.733  0.325
2011 Hasegawa E, Mieda M, Kisanuki Y, Yanagisawa M, Sakurai T. Differential roles of orexin receptor-1 and -2 in the regulation of non-REM and REM sleep Neuroscience Research. 71. DOI: 10.1016/J.Neures.2011.07.732  0.3
2010 Zhang W, Sunanaga J, Takahashi Y, Mori T, Sakurai T, Kanmura Y, Kuwaki T. Orexin neurons are indispensable for stress-induced thermogenesis in mice. The Journal of Physiology. 588: 4117-29. PMID 20807795 DOI: 10.1113/Jphysiol.2010.195099  0.355
2010 Sakurai T, Mieda M, Tsujino N. The orexin system: roles in sleep/wake regulation Annals of the New York Academy of Sciences. 1200: 149-161. PMID 20633143 DOI: 10.1111/J.1749-6632.2010.05513.X  0.341
2010 Furutani N, Hondo M, Tsujino N, Sakurai T. Activation of Bombesin Receptor Subtype-3 Influences Activity of Orexin Neurons by Both Direct and Indirect Pathways Journal of Molecular Neuroscience. 42: 106-111. PMID 20467915 DOI: 10.1007/S12031-010-9382-5  0.395
2010 Mori T, Ito S, Kuwaki T, Yanagisawa M, Sakurai T, Sawaguchi T. Monoaminergic neuronal changes in orexin deficient mice. Neuropharmacology. 58: 826-32. PMID 19703479 DOI: 10.1016/J.Neuropharm.2009.08.009  0.317
2010 Takahashi Y, Sunanaga J, Zhang W, Sakurai T, Kuwaki T. Orexin neurons contribute to prostaglandin E2-induced fever Neuroscience Research. 68: e394. DOI: 10.1016/J.Neures.2010.07.1746  0.309
2010 Sunanaga J, Takahashi Y, Zhang W, Sakurai T, Kuwaki T. Orexin neurons mediate stress-induced hyperthermia Neuroscience Research. 68: e394. DOI: 10.1016/J.Neures.2010.07.1745  0.307
2009 Uchio N, Doi M, Matsuo M, Yamazaki F, Mizoro Y, Hondo M, Sakurai T, Okamura H. Circadian characteristics of mice depleted with GPR7. Biomedical Research-Tokyo. 30: 357-364. PMID 20051645 DOI: 10.2220/Biomedres.30.357  0.32
2009 Mieda M, Sakurai T. Integrative physiology of orexins and orexin receptors. Cns & Neurological Disorders-Drug Targets. 8: 281-295. PMID 19689310 DOI: 10.2174/187152709788921663  0.328
2009 Toyama S, Sakurai T, Tatsumi K, Kuwaki T. Attenuated phrenic long-term facilitation in orexin neuron-ablated mice. Respiratory Physiology & Neurobiology. 168: 295-302. PMID 19664728 DOI: 10.1016/J.Resp.2009.07.025  0.312
2009 Tsujino N, Sakurai T. Orexin/Hypocretin: A Neuropeptide at the Interface of Sleep, Energy Homeostasis, and Reward System Pharmacological Reviews. 61: 162-176. PMID 19549926 DOI: 10.1124/Pr.109.001321  0.377
2009 Zhang W, Zhang N, Sakurai T, Kuwaki T. Orexin neurons in the hypothalamus mediate cardiorespiratory responses induced by disinhibition of the amygdala and bed nucleus of the stria terminalis. Brain Research. 1262: 25-37. PMID 19368849 DOI: 10.1016/J.Brainres.2009.01.022  0.371
2009 Hara J, Gerashchenko D, Wisor JP, Sakurai T, Xie X, Kilduff TS. Thyrotropin-releasing hormone increases behavioral arousal through modulation of hypocretin/orexin neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3705-14. PMID 19321767 DOI: 10.1523/Jneurosci.0431-09.2009  0.351
2009 Matsuki T, Nomiyama M, Takahira H, Hirashima N, Kunita S, Takahashi S, Yagami K, Kilduff TS, Bettler B, Yanagisawa M, Sakurai T. Selective loss of GABA(B) receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture. Proceedings of the National Academy of Sciences of the United States of America. 106: 4459-64. PMID 19246384 DOI: 10.1073/Pnas.0811126106  0.363
2009 Honda M, Eriksson KS, Zhang S, Tanaka S, Lin L, Salehi A, Hesla PE, Maehlen J, Gaus SE, Yanagisawa M, Sakurai T, Taheri S, Tsuchiya K, Honda Y, Mignot E. IGFBP3 colocalizes with and regulates hypocretin (orexin). Plos One. 4: e4254. PMID 19158946 DOI: 10.1371/Journal.Pone.0004254  0.367
2009 Matsuki T, Nomiyama M, Takahira H, Hirashima N, Kunita S, Takahashi S, Yagami KI, Kilduff TS, Bettler B, Yanagisawa M, Sakurai T. Selective loss of GABAB receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 11, (4459-4464) DOI: 10.1073/pnas.0811126106) Proceedings of the National Academy of Sciences of the United States of America. 106: 8790. DOI: 10.1073/Pnas.0903224106  0.332
2009 Sunanaga J, Zhang W, Sakurai T, Kuwaki T. Possible contribution of orexin-containing neurons to stress-induced thermogenesis Neuroscience Research. 65: S184. DOI: 10.1016/J.Neures.2009.09.988  0.311
2009 Furutani N, Abe T, Hondo M, Matsuki T, Tsujino N, Sakurai T. Activity of Orexin-producing neurons is regulated by Neurotensin Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.149  0.341
2009 Tsujino N, Tsunematsu T, Yamanaka A, Koyama Y, Sakurai T. Alterations in monoaminergic neurons in orexin neuron-ablated mice Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.1289  0.346
2008 Kilduff TS, Lein ES, de la Iglesia H, Sakurai T, Fu YH, Shaw P. New developments in sleep research: molecular genetics, gene expression, and systems neurobiology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11814-8. PMID 19005045 DOI: 10.1523/Jneurosci.3768-08.2008  0.301
2008 Liu M, Thankachan S, Kaur S, Begum S, Blanco-Centurion C, Sakurai T, Yanagisawa M, Neve R, Shiromani PJ. Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice. The European Journal of Neuroscience. 28: 1382-93. PMID 18973565 DOI: 10.1111/J.1460-9568.2008.06446.X  0.331
2008 Gerashchenko D, Wisor JP, Burns D, Reh RK, Shiromani PJ, Sakurai T, de la Iglesia HO, Kilduff TS. Identification of a population of sleep-active cerebral cortex neurons. Proceedings of the National Academy of Sciences of the United States of America. 105: 10227-32. PMID 18645184 DOI: 10.1073/Pnas.0803125105  0.347
2008 Yamagata T, Sakurai T, Uchino K, Sezutsu H, Tamura T, Kanzaki R. GFP labeling of neurosecretory cells with the GAL4/UAS system in the silkmoth brain enables selective intracellular staining of neurons. Zoological Science. 25: 509-16. PMID 18558804 DOI: 10.2108/Zsj.25.509  0.314
2008 Xie X, Wisor JP, Hara J, Crowder TL, LeWinter R, Khroyan TV, Yamanaka A, Diano S, Horvath TL, Sakurai T, Toll L, Kilduff TS. Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. The Journal of Clinical Investigation. 118: 2471-81. PMID 18551194 DOI: 10.1172/Jci35115  0.341
2008 Ohno K, Hondo M, Sakurai T. Cholinergic Regulation of Orexin/Hypocretin Neurons Through M3 Muscarinic Receptor in Mice Journal of Pharmacological Sciences. 106: 485-491. PMID 18344611 DOI: 10.1254/Jphs.Fp0071986  0.359
2008 Matsuki T, Sakurai T. Orexins and orexin receptors: from molecules to integrative physiology. Results and Problems in Cell Differentiation. 46: 27-55. PMID 18204827 DOI: 10.1007/400_2007_047  0.317
2008 Tsunematsu T, Fu LY, Yamanaka A, Ichiki K, Tanoue A, Sakurai T, van den Pol AN. Vasopressin increases locomotion through a V1a receptor in orexin/hypocretin neurons: implications for water homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 228-38. PMID 18171940 DOI: 10.1523/Jneurosci.3490-07.2008  0.353
2008 Ohno K, Sakurai T. Orexin neuronal circuitry: role in the regulation of sleep and wakefulness. Frontiers in Neuroendocrinology. 29: 70-87. PMID 17910982 DOI: 10.1016/J.Yfrne.2007.08.001  0.396
2008 Mishima K, Fujiki N, Yoshida Y, Sakurai T, Honda M, Mignot E, Nishino S. Hypocretin Receptor Expression in Canine and Murine Narcolepsy Models and in Hypocretin-Ligand Deficient Human Narcolepsy Sleep. 31: 1119-1126. DOI: 10.5665/Sleep/31.8.1119  0.36
2007 Minami K, Uezono Y, Sakurai T, Horishita T, Shiraishi M, Ueta Y. Effects of anesthetics on the function of orexin-1 receptors expressed in Xenopus oocytes. Pharmacology. 79: 236-242. PMID 17435392 DOI: 10.1159/000101713  0.318
2007 Zhang S, Zeitzer JM, Sakurai T, Nishino S, Mignot E. Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy. The Journal of Physiology. 581: 649-63. PMID 17379635 DOI: 10.1113/Jphysiol.2007.129510  0.319
2007 Zhang W, Sakurai T, Fukuda Y, Kuwaki T. Afferent pathways to the orexinergic neurons that involved in the defense response against stressor The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A475-A  0.324
2007 Sakurai T, Matsuki T, Takahira H, Hirashima N, Kilduff T, Kunita S, Takahashi S, Yagami K, Bettler B, Yanagisawa M, Nomiyama M. Selective loss of GABAB receptors in orexin/hypocretin-producing neurons results in disrupted sleep/wakefulness architecture Nature Precedings. 2: 1-1. DOI: 10.1038/Npre.2007.1195.1  0.388
2007 Nisimaru N, Shirai Y, Fujii M, Sakurai T, Yamamoto M, Ito M. Orexinergic neurons mediate excitatory signals to Purkinje cells in a descrete microzone of the cerebellum Neuroscience Research. 58: S108. DOI: 10.1016/J.Neures.2007.06.1201  0.321
2007 Zhang W, Sakurai T, Fukuda Y, Kuwaki T. Afferent pathways to the orexinergic neurons that involved in the defense response against stressor Autonomic Neuroscience. 135: 54. DOI: 10.1016/J.Autneu.2007.06.079  0.324
2006 Sakurai T. Roles of orexins and orexin receptors in central regulation of feeding behavior and energy homeostasis Cns and Neurological Disorders - Drug Targets. 5: 313-325. PMID 16787231 DOI: 10.2174/187152706777452218  0.361
2006 Takayasu S, Sakurai T, Iwasaki S, Teranishi H, Yamanaka A, Williams SC, Iguchi H, Kawasawa YI, Ikeda Y, Sakakibara I, Ohno K, Ioka RX, Murakami S, Dohmae N, Xie J, et al. A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 7438-43. PMID 16648250 DOI: 10.1073/Pnas.0602371103  0.325
2006 Yamanaka A, Muraki Y, Ichiki K, Tsujino N, Kilduff TS, Goto K, Sakurai T. Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner. Journal of Neurophysiology. 96: 284-98. PMID 16611835 DOI: 10.1152/Jn.01361.2005  0.317
2006 Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, Nakazato M. Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor. Endocrinology. 147: 2306-14. PMID 16484324 DOI: 10.1210/En.2005-1357  0.351
2005 Crocker A, España RA, Papadopoulou M, Saper CB, Faraco J, Sakurai T, Honda M, Mignot E, Scammell TE. Concomitant loss of dynorphin, NARP, and orexin in narcolepsy. Neurology. 65: 1184-8. PMID 16247044 DOI: 10.1212/01.Wnl.0000168173.71940.Ab  0.352
2005 Tsujino N, Yamanaka A, Ichiki K, Muraki Y, Kilduff TS, Yagami K, Takahashi S, Goto K, Sakurai T. Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7459-69. PMID 16093397 DOI: 10.1523/Jneurosci.1193-05.2005  0.342
2005 Sakurai T. Roles of orexin/hypocretin in regulation of sleep/wakefulness and energy homeostasis Sleep Medicine Reviews. 9: 231-241. PMID 15961331 DOI: 10.1016/J.Smrv.2004.07.007  0.359
2005 Hara J, Yanagisawa M, Sakurai T. Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions. Neuroscience Letters. 380: 239-42. PMID 15862893 DOI: 10.1016/J.Neulet.2005.01.046  0.354
2005 Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M. Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice. Neuron. 46: 297-308. PMID 15848807 DOI: 10.1016/J.Neuron.2005.03.010  0.369
2005 Nakagawa T, Sakurai T, Nishioka T, Touhara K. Insect sex-pheromone signals mediated by specific combinations of olfactory receptors. Science (New York, N.Y.). 307: 1638-42. PMID 15692016 DOI: 10.1126/Science.1106267  0.303
2005 Sakurai T. Reverse pharmacology of orexin: From an orphan GPCR to integrative physiology Regulatory Peptides. 126: 3-10. PMID 15620407 DOI: 10.1016/J.Regpep.2004.08.006  0.383
2005 Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M. Erratum: Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice (Neuron (April 21, 2005) 46 (297-308) PII: S0896-6273(05)00205-9 and DOI: 10.1016/j.neuron.2005.03.010) Neuron. 46. DOI: 10.1016/J.Neuron.2005.04.029  0.342
2004 Winsky-Sommerer R, Yamanaka A, Diano S, Borok E, Roberts AJ, Sakurai T, Kilduff TS, Horvath TL, de Lecea L. Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11439-48. PMID 15601950 DOI: 10.1523/Jneurosci.3459-04.2004  0.335
2004 Akiyama M, Yuasa T, Hayasaka N, Horikawa K, Sakurai T, Shibata S. Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated mice European Journal of Neuroscience. 20: 3054-3062. PMID 15579160 DOI: 10.1111/J.1460-9568.2004.03749.X  0.364
2004 Mieda M, Williams SC, Sinton CM, Richardson JA, Sakurai T, Yanagisawa M. Orexin Neurons Function in an Efferent Pathway of a Food-Entrainable Circadian Oscillator in Eliciting Food-Anticipatory Activity and Wakefulness The Journal of Neuroscience. 24: 10493-10501. PMID 15548664 DOI: 10.1523/Jneurosci.3171-04.2004  0.352
2004 Muraki Y, Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T. Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7159-66. PMID 15306649 DOI: 10.1523/Jneurosci.1027-04.2004  0.346
2004 Mochizuki T, Crocker A, McCormack S, Yanagisawa M, Sakurai T, Scammell TE. Behavioral state instability in orexin knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6291-300. PMID 15254084 DOI: 10.1523/Jneurosci.0586-04.2004  0.316
2004 Beuckmann CT, Sinton CM, Williams SC, Richardson JA, Hammer RE, Sakurai T, Yanagisawa M. Expression of a poly-glutamine-ataxin-3 transgene in orexin neurons induces narcolepsy-cataplexy in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4469-77. PMID 15128861 DOI: 10.1523/Jneurosci.5560-03.2004  0.34
2004 Mieda M, Willie JT, Hara J, Sinton CM, Sakurai T, Yanagisawa M. Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 4649-54. PMID 15070772 DOI: 10.1073/Pnas.0400590101  0.387
2004 Muroya S, Funahashi H, Yamanaka A, Kohno D, Uramura K, Nambu T, Shibahara M, Kuramochi M, Takigawa M, Yanagisawa M, Sakurai T, Shioda S, Yada T. Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose-responsive neurons to regulate Ca 2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus. The European Journal of Neuroscience. 19: 1524-34. PMID 15066149 DOI: 10.1111/J.1460-9568.2004.03255.X  0.332
2004 Yamanaka A, Muraki Y, Tsujino N, Goto K, Sakurai T. Regulation of orexin neurons by the monoaminergic and cholinergic systems Sleep and Biological Rhythms. 2. DOI: 10.1111/J.1479-8425.2004.00119.X  0.317
2004 Yamanaka A, Beuckmann CT, Willie JT, Hara J, Tsujino N, Goto K, Yanagisawa M, Sakurai T. Role of hypothalamic orexin neurons in the regulation of arousal according to energy balance Sleep and Biological Rhythms. 2: S57. DOI: 10.1111/J.1479-8425.2004.00116.X  0.327
2003 Zhu Y, Miwa Y, Yamanaka A, Yada T, Shibahara M, Abe Y, Sakurai T, Goto K. Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins. Journal of Pharmacological Sciences. 92: 259-66. PMID 12890892 DOI: 10.1254/Jphs.92.259  0.327
2003 Sakurai T. Orexin: a link between energy homeostasis and adaptive behaviour. Current Opinion in Clinical Nutrition and Metabolic Care. 6: 353-360. PMID 12806206 DOI: 10.1097/01.Mco.0000078995.96795.91  0.37
2003 Yamanaka A, Beuckmann CT, Willie JT, Hara J, Tsujino N, Mieda M, Tominaga M, Yagami Ki, Sugiyama F, Goto K, Yanagisawa M, Sakurai T. Hypothalamic orexin neurons regulate arousal according to energy balance in mice. Neuron. 38: 701-13. PMID 12797956 DOI: 10.1016/S0896-6273(03)00331-3  0.359
2003 Yamanaka A, Muraki Y, Tsujino N, Goto K, Sakurai T. Regulation of orexin neurons by the monoaminergic and cholinergic systems. Biochemical and Biophysical Research Communications. 303: 120-9. PMID 12646175 DOI: 10.1016/S0006-291X(03)00299-7  0.371
2003 Toshinai K, Date Y, Murakami N, Shimada M, Mondal MS, Shimbara T, Guan JL, Wang QP, Funahashi H, Sakurai T, Shioda S, Matsukura S, Kangawa K, Nakazato M. Ghrelin-induced food intake is mediated via the orexin pathway. Endocrinology. 144: 1506-12. PMID 12639935 DOI: 10.1210/En.2002-220788  0.358
2002 Sakurai T. Roles of orexins in the regulation of feeding and arousal Sleep Medicine. 3. PMID 14592371 DOI: 10.1016/S1389-9457(02)00156-9  0.332
2002 Li Y, Gao XB, Sakurai T, van den Pol AN. Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system. Neuron. 36: 1169-81. PMID 12495630 DOI: 10.1016/S0896-6273(02)01132-7  0.356
2002 Zhu L, Onaka T, Sakurai T, Yada T. Activation of orexin neurones after noxious but not conditioned fear stimuli in rats. Neuroreport. 13: 1351-3. PMID 12151801 DOI: 10.1097/00001756-200207190-00027  0.333
2002 Sakurai T. Roles of orexins in regulation of feeding and wakefulness Neuroreport. 13: 987-995. PMID 12060794 DOI: 10.1097/00001756-200206120-00001  0.363
2002 Yamanaka A, Tsujino N, Funahashi H, Honda K, Guan JL, Wang QP, Tominaga M, Goto K, Shioda S, Sakurai T. Orexins activate histaminergic neurons via the orexin 2 receptor. Biochemical and Biophysical Research Communications. 290: 1237-45. PMID 11811995 DOI: 10.1006/Bbrc.2001.6318  0.371
2001 Chou TC, Lee CE, Lu J, Elmquist JK, Hara J, Willie JT, Beuckmann CT, Chemelli RM, Sakurai T, Yanagisawa M, Saper CB, Scammell TE. Orexin (hypocretin) neurons contain dynorphin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: RC168. PMID 11567079 DOI: 10.1523/Jneurosci.21-19-J0003.2001  0.366
2001 Muroya S, Uramura K, Sakurai T, Takigawa M, Yada T. Lowering glucose concentrations increases cytosolic Ca2+ in orexin neurons of the rat lateral hypothalamus. Neuroscience Letters. 309: 165-8. PMID 11514067 DOI: 10.1016/S0304-3940(01)02053-5  0.329
2001 Hara J, Beuckmann CT, Nambu T, Willie JT, Chemelli RM, Sinton CM, Sugiyama F, Yagami K, Goto K, Yanagisawa M, Sakurai T. Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity. Neuron. 30: 345-54. PMID 11394998 DOI: 10.1016/S0896-6273(01)00293-8  0.38
2000 Nanmoku T, Isobe K, Sakurai T, Yamanaka A, Takekoshi K, Kawakami Y, Ishii K, Goto K, Nakai T. Orexins suppress catecholamine synthesis and secretion in cultured PC12 cells. Biochemical and Biophysical Research Communications. 274: 310-315. PMID 10913336 DOI: 10.1006/Bbrc.2000.3137  0.304
1999 Sakurai T. Orexins and orexin receptors: implication in feeding behavior. Regulatory Peptides. 85: 25-30. PMID 10588447 DOI: 10.1016/S0167-0115(99)00076-2  0.367
1999 Sakurai T, Moriguchi T, Furuya K, Kajiwara N, Nakamura T, Yanagisawa M, Goto K. Structure and function of human prepro-orexin gene. Journal of Biological Chemistry. 274: 17771-17776. PMID 10364220 DOI: 10.1074/Jbc.274.25.17771  0.317
1999 Nambu T, Sakurai T, Mizukami K, Hosoya Y, Yanagisawa M, Goto K. Distribution of orexin neurons in the adult rat brain. Brain Research. 827: 243-260. PMID 10320718 DOI: 10.1016/S0006-8993(99)01336-0  0.331
1999 Moriguchi T, Sakurai T, Nambu T, Yanagisawa M, Goto K. Neurons containing orexin in the lateral hypothalamic area of the adult rat brain are activated by insulin-induced acute hypoglycemia. Neuroscience Letters. 264: 101-104. PMID 10320024 DOI: 10.1016/S0304-3940(99)00177-9  0.349
1998 Elias CF, Saper CB, Maratos-Flier E, Tritos NA, Lee C, Kelly J, Tatro JB, Hoffman GE, Ollmann MM, Barsh GS, Sakurai T, Yanagisawa M, Elmquist JK. Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area. The Journal of Comparative Neurology. 402: 442-59. PMID 9862320 DOI: 10.1002/(Sici)1096-9861(19981228)402:4<442::Aid-Cne2>3.0.Co;2-R  0.334
1998 Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richardson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 92: 573-85. PMID 9491897 DOI: 10.1016/S0092-8674(00)80949-6  0.314
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