Emma Lofthouse - Publications

Affiliations: 
Human Development & Health University of Southampton, Southampton, England, United Kingdom 

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lofthouse EM, Cleal J, Lewis RM, Sengers BG. Computational Modelling of Paracellular Diffusion and OCT3 Mediated Transport of Metformin in the Perfused Human Placenta. Journal of Pharmaceutical Sciences. PMID 37211316 DOI: 10.1016/j.xphs.2023.05.008  0.565
2022 Lewis RM, Baskaran H, Green J, Tashev S, Palaiologou E, Lofthouse EM, Cleal JK, Page A, Chatelet DS, Goggin P, Sengers BG. 3D visualization of trans-syncytial nanopores provides a pathway for paracellular diffusion across the human placental syncytiotrophoblast. Iscience. 25: 105453. PMID 36387021 DOI: 10.1016/j.isci.2022.105453  0.524
2022 Ashley B, Simner C, Manousopoulou A, Jenkinson C, Hey F, Frost JM, Rezwan FI, White CH, Lofthouse EM, Hyde E, Cooke LDF, Barton S, Mahon P, Curtis EM, Moon RJ, et al. Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit. Elife. 11. PMID 35256050 DOI: 10.7554/eLife.71094  0.728
2021 Tashev SA, Parsons D, Hillman C, Harris S, Lofthouse EM, Goggin P, Chatelet DS, Cleal JK, Smyth N, Palaiologou H, Page A, Lewis RM. Folding of the syncytiotrophoblast basal plasma membrane increases the surface area available for exchange in human placenta. Placenta. 117: 57-63. PMID 34768170 DOI: 10.1016/j.placenta.2021.11.002  0.571
2021 Lofthouse EM, Manousopoulou A, Cleal JK, O'Kelly IM, Poore KR, Garbis SD, Lewis RM. N-acetylcysteine, xCT and suppression of Maxi-chloride channel activity in human placenta. Placenta. 110: 46-55. PMID 34120018 DOI: 10.1016/j.placenta.2021.05.009  0.474
2020 Harris SE, Matthews KS, Palaiologou E, Tashev SA, Lofthouse EM, Pearson-Farr J, Goggin P, Chatelet DS, Johnston DA, Jongen MS, Page AM, Cleal JK, Lewis RM. Pericytes on placental capillaries in terminal villi preferentially cover endothelial junctions in regions furthest away from the trophoblast. Placenta. 104: 1-7. PMID 33190063 DOI: 10.1016/j.placenta.2020.10.032  0.462
2020 Lofthouse EM, Cleal JK, Hudson G, Lewis RM, Sengers BG. Glibenclamide transfer across the perfused human placenta is determined by albumin binding not transporter activity. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 152: 105436. PMID 32592753 DOI: 10.1016/j.ejps.2020.105436  0.531
2020 Palaiologou E, Goggin P, Chatelet DS, Ribeiro de Souza R, Chiu W, Ashley B, Lofthouse EM, Sengers BG, Torrens C, Page AM, Cleal JK, Lewis RM. Serial block-face scanning electron microscopy reveals novel intercellular connections in human term placental microvasculature. Journal of Anatomy. PMID 32242928 DOI: 10.1111/Joa.13191  0.722
2019 Lofthouse EM, Torrens C, Manousopoulou A, Nahar M, Cleal JK, O'Kelly IM, Sengers BG, Garbis SD, Lewis RM. Ursodeoxycholic acid inhibits uptake and vasoconstrictor effects of taurocholate in human placenta. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900015RR. PMID 30922127 DOI: 10.1096/Fj.201900015Rr  0.525
2019 Ashley B, Lofthouse E, Hey F, Jones K, Harvey N, Lewis R, Cleal J. Human placental metabolism of vitamin D and transfer to maternal and fetal circulations Placenta. 83: e114. DOI: 10.1016/J.Placenta.2019.06.359  0.73
2018 Lofthouse EM, Cleal JK, O'Kelly IM, Sengers BG, Lewis RM. Estrone sulphate uptake by the microvillous membrane of placental syncytiotrophoblast is coupled to glutamate efflux. Biochemical and Biophysical Research Communications. PMID 30343886 DOI: 10.1016/j.bbrc.2018.10.074  0.495
2018 Cleal JK, Lofthouse EM, Sengers BG, Lewis RM. A systems perspective on placental amino acid transport. The Journal of Physiology. PMID 29984402 DOI: 10.1113/JP274883  0.489
2017 Palaiologou E, Goggin P, Chatelet DS, Lofthouse EM, Torrens C, Sengers BG, Cleal JK, Page A, Lewis RM. Serial block-face scanning electron microscopy of erythrocytes protruding through the human placental syncytiotrophoblast. Journal of Anatomy. PMID 28714092 DOI: 10.1111/Joa.12658  0.55
2017 Lofthouse E, Sengers B, Lewis R. The role of placental OATP4A1 in obstetric cholestasis Placenta. 57: 250. DOI: 10.1016/J.Placenta.2017.07.095  0.526
2016 Palaiologou E, Chiu W, de Souza RR, Goggin P, Lofthouse E, Cleal J, Page A, Lewis R. High resolution three dimensional imaging of placental villi using serial block face scanning electron microscopy Placenta. 45: 84. DOI: 10.1016/J.Placenta.2016.06.083  0.472
2015 Lofthouse EM, Perazzolo S, Brooks S, Crocker IP, Glazier JD, Johnstone ED, Panitchob N, Sibley CP, Widdows KL, Sengers BG, Lewis RM. Phenylalanine transfer across the isolated perfused human placenta: an experimental and modelling investigation. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00405.2015. PMID 26676251 DOI: 10.1152/ajpregu.00405.2015  0.55
2015 Lofthouse EM, Brooks S, Cleal JK, Hanson MA, Poore KR, O'Kelly IM, Lewis RM. Glutamate cycling may drive organic anion transport on the basal membrane of human placental syncytiotrophoblast. The Journal of Physiology. PMID 26277985 DOI: 10.1113/Jp270743  0.499
2014 Widdows K, Panitchob N, Lofthouse E, Crocker I, Sibley C, Please C, Johnstone E, Sengers B, Lewis R, Glazier J. Activation by intravesicular amino acids of system L-mediated serine uptake into human placental microvillous plasma membrane vesicles Placenta. 35: A99. DOI: 10.1016/J.Placenta.2014.06.321  0.546
2013 Day PE, Cleal JK, Lofthouse EM, Goss V, Koster G, Postle A, Jackson JM, Hanson MA, Jackson AA, Lewis RM. Partitioning of glutamine synthesised by the isolated perfused human placenta between the maternal and fetal circulations. Placenta. 34: 1223-31. PMID 24183194 DOI: 10.1016/J.Placenta.2013.10.003  0.754
2013 Day PE, Cleal JK, Lofthouse EM, Hanson MA, Lewis RM. What factors determine placental glucose transfer kinetics? Placenta. 34: 953-8. PMID 23886770 DOI: 10.1016/J.Placenta.2013.07.001  0.733
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