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Colin McKerlie - Publications

Affiliations: 
University of Guelph (Canada), Guelph, Ontario, Canada 
 University of Toronto, Toronto, ON, Canada 
Area:
Oncology, Pathology, Biomedical Engineering
Website:
https://lmp.utoronto.ca/faculty/colin-mckerlie
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Higgins K, Moore BA, Berberovic Z, Adissu HA, Eskandarian M, Flenniken AM, Shao A, Imai DM, Clary D, Lanoue L, Newbigging S, Nutter LMJ, Adams DJ, Bosch F, Braun RE, ... ... McKerlie C, et al. Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes. Scientific Reports. 12: 20791. PMID 36456625 DOI: 10.1038/s41598-022-19710-7  0.711
2022 Cacheiro P, Westerberg CH, Mager J, Dickinson ME, Nutter LMJ, Muñoz-Fuentes V, Hsu CW, Van den Veyver IB, Flenniken AM, McKerlie C, Murray SA, Teboul L, Heaney JD, Lloyd KCK, Lanoue L, et al. Mendelian gene identification through mouse embryo viability screening. Genome Medicine. 14: 119. PMID 36229886 DOI: 10.1186/s13073-022-01118-7  0.33
2021 Wotton JM, Peterson E, Flenniken AM, Bains RS, Veeraragavan S, Bower LR, Bubier JA, Parisien M, Bezginov A, Haselimashhadi H, Mason J, Moore MA, Stewart ME, Clary DA, Delbarre DJ, ... ... McKerlie C, et al. Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen. Pain. 163: 1139-1157. PMID 35552317 DOI: 10.1097/j.pain.0000000000002481  0.311
2021 Mohammed Y, Michaud SA, Pětrošová H, Yang J, Ganguly M, Schibli D, Flenniken AM, Nutter LMJ, Adissu HA, Lloyd KCK, McKerlie C, Borchers CH. Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma. Npj Systems Biology and Applications. 7: 25. PMID 34050187 DOI: 10.1038/s41540-021-00184-8  0.68
2020 Herbert E, Stewart M, Hutchison M, Flenniken AM, Qu D, Nutter LMJ, McKerlie C, Hobson L, Kick B, Lyons B, Wiegand JP, Doty R, Aguilar-Pimentel JA, Hrabe de Angelis M, Dickinson M, et al. The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities. Plos One. 15: e0230162. PMID 32542000 DOI: 10.1371/Journal.Pone.0230162  0.349
2020 Lloyd KCK, Adams DJ, Baynam G, Beaudet AL, Bosch F, Boycott KM, Braun RE, Caulfield M, Cohn R, Dickinson ME, Dobbie MS, Flenniken AM, Flicek P, Galande S, Gao X, ... ... McKerlie C, et al. The Deep Genome Project. Genome Biology. 21: 18. PMID 32008577 DOI: 10.1186/S13059-020-1931-9  0.317
2020 Cacheiro P, Muñoz-Fuentes V, Murray SA, Dickinson ME, Bucan M, Nutter LMJ, Peterson KA, Haselimashhadi H, Flenniken AM, Morgan H, Westerberg H, Konopka T, Hsu CW, Christiansen A, Lanza DG, ... ... McKerlie C, et al. Human and mouse essentiality screens as a resource for disease gene discovery. Nature Communications. 11: 655. PMID 32005800 DOI: 10.1038/S41467-020-14284-2  0.458
2020 Zhang T, Xie P, Dong Y, Liu Z, Zhou F, Pan D, Huang Z, Zhai Q, Gu Y, Wu Q, Tanaka N, Obata Y, Bradley A, Lelliott CJ, ... ... McKerlie C, et al. High-throughput discovery of genetic determinants of circadian misalignment. Plos Genetics. 16: e1008577. PMID 31929527 DOI: 10.1371/Journal.Pgen.1008577  0.368
2019 Moore BA, Flenniken AM, Clary D, Moshiri AS, Nutter LMJ, Berberovic Z, Owen C, Newbigging S, Adissu H, Eskandarian M, McKerlie C, Thomasy SM, Lloyd KCK, Murphy CJ, et al. Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function. Scientific Reports. 9: 11211. PMID 31371754 DOI: 10.1038/S41598-019-47286-2  0.724
2019 Barupal DK, Zhang Y, Shen T, Fan S, Roberts BS, Fitzgerald P, Wancewicz B, Valdiviez L, Wohlgemuth G, Byram G, Choy YY, Haffner B, Showalter MR, Vaniya A, Bloszies CS, ... ... McKerlie C, et al. A Comprehensive Plasma Metabolomics Dataset for a Cohort of Mouse Knockouts within the International Mouse Phenotyping Consortium. Metabolites. 9. PMID 31121816 DOI: 10.3390/Metabo9050101  0.39
2019 Moore BA, Leonard BC, Sebbag L, Edwards SG, Cooper A, Imai DM, Straiton E, Santos L, Reilly C, Griffey SM, Bower L, Clary D, Mason J, Roux MJ, Meziane H, ... ... McKerlie C, et al. Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts. Communications Biology. 2: 97. PMID 30854487 DOI: 10.1038/s42003-019-0349-y  0.665
2018 Moore BA, Leonard BC, Sebbag L, Edwards SG, Cooper A, Imai DM, Straiton E, Santos L, Reilly C, Griffey SM, Bower L, Clary D, Mason J, Roux MJ, Meziane H, ... ... McKerlie C, et al. Identification of genes required for eye development by high-throughput screening of mouse knockouts. Communications Biology. 1: 236. PMID 30588515 DOI: 10.1038/s42003-018-0226-0  0.704
2018 Muñoz-Fuentes V, Cacheiro P, Meehan TF, Aguilar-Pimentel JA, Brown SDM, Flenniken AM, Flicek P, Galli A, Mashhadi HH, Hrabě de Angelis M, Kim JK, Lloyd KCK, McKerlie C, Morgan H, Murray SA, et al. The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation. Conservation Genetics (Print). 19: 995-1005. PMID 30100824 DOI: 10.1007/S10592-018-1072-9  0.344
2018 Rozman J, Rathkolb B, Oestereicher MA, Schütt C, Ravindranath AC, Leuchtenberger S, Sharma S, Kistler M, Willershäuser M, Brommage R, Meehan TF, Mason J, Haselimashhadi H, Hough T, ... ... McKerlie C, et al. Identification of genetic elements in metabolism by high-throughput mouse phenotyping. Nature Communications. 9: 288. PMID 29348434 DOI: 10.1038/S41467-017-01995-2  0.388
2017 Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, ... ... McKerlie C, et al. Corrigendum: High-throughput discovery of novel developmental phenotypes. Nature. 551: 398. PMID 29144450 DOI: 10.1038/Nature24643  0.659
2017 Karp NA, Mason J, Beaudet AL, Benjamini Y, Bower L, Braun RE, Brown SDM, Chesler EJ, Dickinson ME, Flenniken AM, Fuchs H, Angelis MH, Gao X, Guo S, Greenaway S, ... ... McKerlie C, et al. Prevalence of sexual dimorphism in mammalian phenotypic traits. Nature Communications. 8: 15475. PMID 28650954 DOI: 10.1038/Ncomms15475  0.349
2017 Meehan TF, Conte N, West DB, Jacobsen JO, Mason J, Warren J, Chen CK, Tudose I, Relac M, Matthews P, Karp N, Santos L, Fiegel T, Ring N, Westerberg H, ... ... McKerlie C, et al. Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium. Nature Genetics. PMID 28650483 DOI: 10.1038/Ng.3901  0.458
2016 Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, ... ... McKerlie C, et al. High-throughput discovery of novel developmental phenotypes. Nature. PMID 27626380 DOI: 10.1038/Nature19356  0.72
2015 Katsifa A, Kaffe E, Nikolaidou-Katsaridou N, Economides AN, Newbigging S, McKerlie C, Aidinis V. The Bulk of Autotaxin Activity Is Dispensable for Adult Mouse Life. Plos One. 10: e0143083. PMID 26569406 DOI: 10.1371/Journal.Pone.0143083  0.346
2015 Adissu HA, McKerlie C, Di Grappa M, Waterhouse P, Xu Q, Fang H, Khokha R, Wood GA. Timp3 loss accelerates tumour invasion and increases prostate inflammation in a mouse model of prostate cancer. The Prostate. PMID 26332574 DOI: 10.1002/Pros.23056  0.628
2015 de Angelis MH, Nicholson G, Selloum M, White JK, Morgan H, Ramirez-Solis R, Sorg T, Wells S, Fuchs H, Fray M, Adams DJ, Adams NC, Adler T, Aguilar-Pimentel A, Ali-Hadji D, ... ... McKerlie C, et al. Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics. Nature Genetics. PMID 26214591 DOI: 10.1038/Ng.3360  0.477
2015 Adissu HA, Medhanie GA, Morikawa L, White JK, Newbigging S, McKerlie C. Right Ventricular Epicardial Fibrosis in Mice With Sternal Segment Dislocation. Veterinary Pathology. 52: 967-76. PMID 25281652 DOI: 10.1177/0300985814552108  0.663
2014 Adissu HA, Estabel J, Sunter D, Tuck E, Hooks Y, Carragher DM, Clarke K, Karp NA, Newbigging S, Jones N, Morikawa L, White JK, McKerlie C. Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. Disease Models & Mechanisms. 7: 515-24. PMID 24652767 DOI: 10.1242/Dmm.015263  0.693
2014 Inoue S, Tomasini R, Rufini A, Elia AJ, Agostini M, Amelio I, Cescon D, Dinsdale D, Zhou L, Harris IS, Lac S, Silvester J, Li WY, Sasaki M, Haight J, ... ... McKerlie C, et al. TAp73 is required for spermatogenesis and the maintenance of male fertility. Proceedings of the National Academy of Sciences of the United States of America. 111: 1843-8. PMID 24449892 DOI: 10.1073/Pnas.1323416111  0.355
2013 Schofield PN, Sundberg JP, Sundberg BA, McKerlie C, Gkoutos GV. The mouse pathology ontology, MPATH; structure and applications. Journal of Biomedical Semantics. 4: 18. PMID 24033988 DOI: 10.1186/2041-1480-4-18  0.323
2013 Kelsey L, Flenniken AM, Qu D, Funnell AP, Pearson R, Zhou YQ, Voronina I, Berberovic Z, Wood G, Newbigging S, Weiss ES, Wong M, Quach I, Yeh SY, Deshwar AR, ... ... McKerlie C, et al. ENU-induced mutation in the DNA-binding domain of KLF3 reveals important roles for KLF3 in cardiovascular development and function in mice. Plos Genetics. 9: e1003612. PMID 23874215 DOI: 10.1371/Journal.Pgen.1003612  0.376
2013 Chang I, Bramall AN, Baynash AG, Rattner A, Rakheja D, Post M, Joza S, McKerlie C, Stewart DJ, McInnes RR, Yanagisawa M. Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice. The Journal of Clinical Investigation. 123: 2643-53. PMID 23676500 DOI: 10.1172/Jci66735  0.357
2013 Samplaski M, Zhu Y, Hou H, Savio A, Bapat B, Bader G, McKerlie C, Jarvi K, Lo K. 2035 EPIGENETIC REGULATION OF GENE EXPRESSION PATTERNS IN HUMAN TESTIS XENOTRANSPLANTS AFTER TREATMENT WITH CYCLOPHOSPHAMIDE Journal of Urology. 189. DOI: 10.1016/J.Juro.2013.02.2454  0.309
2012 Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, ... ... McKerlie C, et al. The mammalian gene function resource: the International Knockout Mouse Consortium. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 580-6. PMID 22968824 DOI: 10.1007/S00335-012-9422-2  0.44
2012 Donahue LR, Hrabe de Angelis M, Hagn M, Franklin C, Lloyd KC, Magnuson T, McKerlie C, Nakagata N, Obata Y, Read S, Wurst W, Hörlein A, Davisson MT. Centralized mouse repositories. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 559-71. PMID 22945696 DOI: 10.1007/S00335-012-9420-4  0.338
2011 Schofield PN, Dubus P, Klein L, Moore M, McKerlie C, Ward JM, Sundberg JP. Pathology of the laboratory mouse: an International Workshop on Challenges for High Throughput Phenotyping. Toxicologic Pathology. 39: 559-62. PMID 21444746 DOI: 10.1177/0192623311399789  0.416
2011 Ye L, Zhu W, Backx PH, Cortez MA, Wu J, Chow YH, McKerlie C, Wang A, Tsui LC, Gross GJ, Hu J. Arrhythmia and sudden death associated with elevated cardiac chloride channel activity. Journal of Cellular and Molecular Medicine. 15: 2307-16. PMID 21155978 DOI: 10.1111/J.1582-4934.2010.01243.X  0.317
2008 Yildiz C, Fleming C, Ottaviani P, McKerlie C. Fresh and frozen-thawed sperm quality, nuclear DNA integrity, invitro fertility, embryo development, and live-born offspring of N-ethyl-N-nitrosourea (ENU) mice. Cryobiology. 57: 156-62. PMID 18700137 DOI: 10.1016/J.Cryobiol.2008.07.007  0.343
2007 Lee SU, Grigorian A, Pawling J, Chen IJ, Gao G, Mozaffar T, McKerlie C, Demetriou M. N-glycan processing deficiency promotes spontaneous inflammatory demyelination and neurodegeneration. The Journal of Biological Chemistry. 282: 33725-34. PMID 17855338 DOI: 10.1074/Jbc.M704839200  0.326
2007 Yildiz C, Ottaviani P, Law N, Ayearst R, Liu L, McKerlie C. Effects of cryopreservation on sperm quality, nuclear DNA integrity, in vitro fertilization, and in vitro embryo development in the mouse. Reproduction (Cambridge, England). 133: 585-95. PMID 17379653 DOI: 10.1530/Rep-06-0256  0.31
2007 Tremblay LO, Nagy Kovács E, Daniels E, Wong NK, Sutton-Smith M, Morris HR, Dell A, Marcinkiewicz E, Seidah NG, McKerlie C, Herscovics A. Respiratory distress and neonatal lethality in mice lacking Golgi alpha1,2-mannosidase IB involved in N-glycan maturation. The Journal of Biological Chemistry. 282: 2558-66. PMID 17121831 DOI: 10.1074/Jbc.M608661200  0.37
2006 McKerlie C. Cause and effect considerations in diagnostic pathology and pathology phenotyping of genetically engineered mice (GEM). Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 47: 156-62. PMID 16547372  0.332
2005 Flenniken AM, Osborne LR, Anderson N, Ciliberti N, Fleming C, Gittens JE, Gong XQ, Kelsey LB, Lounsbury C, Moreno L, Nieman BJ, Peterson K, Qu D, Roscoe W, Shao Q, ... ... McKerlie C, et al. A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. Development (Cambridge, England). 132: 4375-86. PMID 16155213 DOI: 10.1242/Dev.02011  0.389
2005 Wood GA, Flenniken A, Osborne L, Fleming C, Vukobradovic I, Morikawa L, Xu Q, Porter R, Adamson SL, Rossant J, McKerlie C. Two mouse mutations mapped to chromosome 11 with differing morphologies but similar progressive inflammatory alopecia Experimental Dermatology. 14: 373-379. PMID 15854131 DOI: 10.1111/J.0906-6705.2005.00291.X  0.353
2004 Chow RL, Volgyi B, Szilard RK, Ng D, McKerlie C, Bloomfield SA, Birch DG, McInnes RR. Control of late off-center cone bipolar cell differentiation and visual signaling by the homeobox gene Vsx1. Proceedings of the National Academy of Sciences of the United States of America. 101: 1754-9. PMID 14745032 DOI: 10.1073/Pnas.0306520101  0.337
2003 Koehler DR, Sajjan U, Chow YH, Martin B, Kent G, Tanswell AK, McKerlie C, Forstner JF, Hu J. Protection of Cftr knockout mice from acute lung infection by a helper-dependent adenoviral vector expressing Cftr in airway epithelia. Proceedings of the National Academy of Sciences of the United States of America. 100: 15364-9. PMID 14673110 DOI: 10.1073/Pnas.2436478100  0.377
2003 Wong JC, Alon N, Mckerlie C, Huang JR, Meyn MS, Buchwald M. Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia. Human Molecular Genetics. 12: 2063-76. PMID 12913077 DOI: 10.1093/Hmg/Ddg219  0.423
2003 Copland IB, Kavanagh BP, Engelberts D, McKerlie C, Belik J, Post M. Early changes in lung gene expression due to high tidal volume. American Journal of Respiratory and Critical Care Medicine. 168: 1051-9. PMID 12816737 DOI: 10.1164/Rccm.200208-964Oc  0.363
2003 Pan Y, Zvaritch E, Tupling AR, Rice WJ, de Leon S, Rudnicki M, McKerlie C, Banwell BL, MacLennan DH. Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice. The Journal of Biological Chemistry. 278: 13367-75. PMID 12556521 DOI: 10.1074/Jbc.M213228200  0.346
2002 Haston CK, McKerlie C, Newbigging S, Corey M, Rozmahel R, Tsui LC. Detection of modifier loci influencing the lung phenotype of cystic fibrosis knockout mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 13: 605-13. PMID 12461645 DOI: 10.1007/S00335-002-2190-7  0.384
2002 Winer S, Astsaturov I, Cheung R, Tsui H, Song A, Gaedigk R, Winer D, Sampson A, McKerlie C, Bookman A, Dosch HM. Primary Sjögren's syndrome and deficiency of ICA69. Lancet (London, England). 360: 1063-9. PMID 12383988 DOI: 10.1016/S0140-6736(02)11144-5  0.342
2002 Yang Y, McKerlie C, Borenstein SH, Lu Z, Schito M, Chamberlain JW, Buchwald M. Transgenic expression in mouse lung reveals distinct biological roles for the adenovirus type 5 E1A 243- and 289-amino-acid proteins. Journal of Virology. 76: 8910-9. PMID 12163610 DOI: 10.1128/Jvi.76.17.8910-8919.2002  0.316
2001 Rossant J, McKerlie C. Mouse-based phenogenomics for modelling human disease. Trends in Molecular Medicine. 7: 502-507. PMID 11689335 DOI: 10.1016/S1471-4914(01)02164-5  0.441
1998 Carreau M, Gan OI, Liu L, Doedens M, McKerlie C, Dick JE, Buchwald M. Bone marrow failure in the Fanconi anemia group C mouse model after DNA damage. Blood. 91: 2737-44. PMID 9531583 DOI: 10.1182/Blood.V91.8.2737.2737_2737_2744  0.341
1997 Kent G, Iles R, Bear CE, Huan LJ, Griesenbach U, McKerlie C, Frndova H, Ackerley C, Gosselin D, Radzioch D, O'Brodovich H, Tsui LC, Buchwald M, Tanswell AK. Lung disease in mice with cystic fibrosis. The Journal of Clinical Investigation. 100: 3060-9. PMID 9399953 DOI: 10.1172/Jci119861  0.35
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