Graeme F. Nixon - Publications

Affiliations: 
Department of Biomedical Sciences University of Aberdeen, Aberdeen, Scotland, United Kingdom 

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lewis CT, Mascall KS, Wilson HM, Small GR, Kerr KM, Gibson G, Nixon GF. 3M03 Soluble fms-like tyrosine kinase 1 (sFlt1) is downregulated in aortic valve stenosis, promoting intravalvular neovascularisation Heart. 105. DOI: 10.1136/Heartjnl-2019-Scf.3  0.314
2017 Greig FH, Kennedy S, Gibson G, Ramos JW, Nixon GF. PEA-15 (Phosphoprotein Enriched in Astrocytes 15) Is a Protective Mediator in the Vasculature and Is Regulated During Neointimal Hyperplasia. Journal of the American Heart Association. 6. PMID 28893763 DOI: 10.1161/Jaha.117.006936  0.482
2016 Wirrig C, McKean JS, Wilson HM, Nixon GF. Sphingosylphosphorylcholine inhibits macrophage adhesion to vascular smooth muscle cells. Biochemical Pharmacology. PMID 27402344 DOI: 10.1016/J.Bcp.2016.07.004  0.474
2015 McKean JS, Murray F, Gibson G, Shewan DA, Tucker SJ, Nixon GF. The cAMP-producing agonist beraprost inhibits human vascular smooth muscle cell migration via exchange protein directly activated by cAMP. Cardiovascular Research. PMID 26092100 DOI: 10.1093/Cvr/Cvv176  0.434
2014 Greig FH, Nixon GF. Phosphoprotein enriched in astrocytes (PEA)-15: a potential therapeutic target in multiple disease states. Pharmacology & Therapeutics. 143: 265-74. PMID 24657708 DOI: 10.1016/J.Pharmthera.2014.03.006  0.336
2013 Ou O, Allen-Redpath K, Urgast D, Gordon MJ, Campbell G, Feldmann J, Nixon GF, Mayer CD, Kwun IS, Beattie JH. Plasma zinc's alter ego is a low-molecular-weight humoral factor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3672-82. PMID 23729592 DOI: 10.1096/Fj.13-228791  0.325
2013 Allen-Redpath K, Ou O, Beattie JH, Kwun IS, Feldmann J, Nixon GF. Marginal dietary zinc deficiency in vivo induces vascular smooth muscle cell apoptosis in large arteries. Cardiovascular Research. 99: 525-534. PMID 23667188 DOI: 10.1093/Cvr/Cvt114  0.429
2013 Alcantara EH, Shin MY, Feldmann J, Nixon GF, Beattie JH, Kwun IS. Long-term zinc deprivation accelerates rat vascular smooth muscle cell proliferation involving the down-regulation of JNK1/2 expression in MAPK signaling Atherosclerosis. 228: 46-52. PMID 23466072 DOI: 10.1016/J.Atherosclerosis.2013.01.030  0.453
2012 Mascall KS, Small GR, Gibson G, Nixon GF. Sphingosine-1-phosphate-induced release of TIMP-2 from vascular smooth muscle cells inhibits angiogenesis. Journal of Cell Science. 125: 2267-75. PMID 22344262 DOI: 10.1242/Jcs.099044  0.435
2011 Hunter I, Mascall KS, Ramos JW, Nixon GF. A phospholipase Cγ1-activated pathway regulates transcription in human vascular smooth muscle cells. Cardiovascular Research. 90: 557-64. PMID 21285289 DOI: 10.1093/Cvr/Cvr039  0.444
2011 Wirrig C, Hunter I, Mathieson FA, Nixon GF. Sphingosylphosphorylcholine is a proinflammatory mediator in cerebral arteries. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 212-21. PMID 20551970 DOI: 10.1038/Jcbfm.2010.79  0.401
2009 Wilson AM, Brittenden J, Bachoo P, Ford I, Nixon GF. Randomized controlled trial of aspirin and clopidogrel versus aspirin and placebo on markers of smooth muscle proliferation before and after peripheral angioplasty. Journal of Vascular Surgery. 50: 861-9. PMID 19786240 DOI: 10.1016/J.Jvs.2009.06.017  0.413
2009 Nixon GF. Sphingolipids in inflammation: pathological implications and potential therapeutic targets. British Journal of Pharmacology. 158: 982-93. PMID 19563535 DOI: 10.1111/J.1476-5381.2009.00281.X  0.323
2008 David KC, Scott RH, Nixon GF. Advanced glycation endproducts induce a proliferative response in vascular smooth muscle cells via altered calcium signaling. Biochemical Pharmacology. 76: 1110-20. PMID 18775682 DOI: 10.1016/J.Bcp.2008.08.011  0.434
2008 Kinnear NP, Wyatt CN, Clark JH, Calcraft PJ, Fleischer S, Jeyakumar LH, Nixon GF, Evans AM. Lysosomes co-localize with ryanodine receptor subtype 3 to form a trigger zone for calcium signalling by NAADP in rat pulmonary arterial smooth muscle. Cell Calcium. 44: 190-201. PMID 18191199 DOI: 10.1016/J.Ceca.2007.11.003  0.361
2008 Nixon GF, Mathieson FA, Hunter I. The multi-functional role of sphingosylphosphorylcholine. Progress in Lipid Research. 47: 62-75. PMID 18042469 DOI: 10.1016/J.Plipres.2007.11.001  0.342
2007 Nixon GF, Mathieson FA, Hunter I. The potential roles of sphingolipids in vascular smooth-muscle function. Biochemical Society Transactions. 35: 908-909. PMID 17956243 DOI: 10.1042/Bst0350908  0.434
2006 Hunter I, Nixon GF. Spatial compartmentalization of tumor necrosis factor (TNF) receptor 1-dependent signaling pathways in human airway smooth muscle cells. Lipid rafts are essential for TNF-alpha-mediated activation of RhoA but dispensable for the activation of the NF-kappaB and MAPK pathways. The Journal of Biological Chemistry. 281: 34705-15. PMID 16982613 DOI: 10.1074/Jbc.M605738200  0.402
2006 Mathieson FA, Nixon GF. Sphingolipids differentially regulate mitogen-activated protein kinases and intracellular Ca2+ in vascular smooth muscle: effects on CREB activation. British Journal of Pharmacology. 147: 351-9. PMID 16402047 DOI: 10.1038/Sj.Bjp.0706600  0.45
2005 Egan CG, Wainwright CL, Wadsworth RM, Nixon GF. PDGF-induced signaling in proliferating and differentiated vascular smooth muscle: effects of altered intracellular Ca2+ regulation. Cardiovascular Research. 67: 308-16. PMID 15885673 DOI: 10.1016/J.Cardiores.2005.03.019  0.463
2004 Egan CG, Nixon GF. Endothelin-1- and depolarization-induced differential regulation of cAMP response element-binding protein in proliferating and developed vascular smooth muscle. Cellular Signalling. 16: 1387-96. PMID 15381254 DOI: 10.1016/J.Cellsig.2004.04.008  0.452
2004 Egan CG, Nixon GF. Pdgf-Induced Regulation Of Erk 1/2 Activation In Native Vascular Smooth Muscle: Comparison In Developing And Fully Differentiated Phenotypes Cardiovascular Pathology. 13: 46-47. DOI: 10.1016/J.Carpath.2004.03.133  0.46
2003 Coussin F, Scott RH, Nixon GF. Sphingosine 1-phosphate induces CREB activation in rat cerebral artery via a protein kinase C-mediated inhibition of voltage-gated K+ channels. Biochemical Pharmacology. 66: 1861-70. PMID 14563496 DOI: 10.1016/S0006-2952(03)00546-X  0.443
2003 Hunter I, Cobban HJ, Vandenabeele P, MacEwan DJ, Nixon GF. Tumor necrosis factor-alpha-induced activation of RhoA in airway smooth muscle cells: role in the Ca2+ sensitization of myosin light chain20 phosphorylation. Molecular Pharmacology. 63: 714-21. PMID 12606782 DOI: 10.1124/Mol.63.3.714  0.412
2002 Coussin F, Scott RH, Wise A, Nixon GF. Comparison of sphingosine 1-phosphate-induced intracellular signaling pathways in vascular smooth muscles: differential role in vasoconstriction. Circulation Research. 91: 151-7. PMID 12142348 DOI: 10.1161/01.Res.0000028150.51130.36  0.43
2001 Bodie SL, Ford I, Greaves M, Nixon GF. Thrombin-induced activation of RhoA in platelet shape change Biochemical and Biophysical Research Communications. 287: 71-76. PMID 11549255 DOI: 10.1006/Bbrc.2001.5547  0.356
2001 McFarlane SM, Jupp OJ, Cobban HJ, Hunter I, Anderson HM, Vandenabeele P, Nixon GF, MacEwan DJ. Stimulation of stress-activated but not mitogen-activated protein kinases by tumour necrosis factor receptor subtypes in airway smooth muscle. Biochemical Pharmacology. 61: 749-59. PMID 11266661 DOI: 10.1016/S0006-2952(01)00530-5  0.423
2000 Tasker PN, Taylor CW, Nixon GF. Expression and Distribution of InsP3 Receptor Subtypes in Proliferating Vascular Smooth Muscle Cells Biochemical and Biophysical Research Communications. 273: 907-912. PMID 10891346 DOI: 10.1006/Bbrc.2000.3036  0.42
1999 Parris JRM, Cobban HJ, Littlejohn AF, MacEwan DJ, Nixon GF. Tumour necrosis factor-α activates a calcium sensitization pathway in guinea-pig bronchial smooth muscle Journal of Physiology. 518: 561-569. PMID 10381600 DOI: 10.1111/J.1469-7793.1999.0561P.X  0.465
1999 Evans AM, Cobban HJ, Nixon GF. ET(A) receptors are the primary mediators of myofilament calcium sensitization induced by ET-1 in rat pulmonary artery smooth muscle: A tyrosine kinase independent pathway British Journal of Pharmacology. 127: 153-160. PMID 10369468 DOI: 10.1038/Sj.Bjp.0702548  0.369
1999 Tasker PN, Michelangeli F, Nixon GF. Expression and Distribution of the Type 1 and Type 3 Inositol 1,4,5-Trisphosphate Receptor in Developing Vascular Smooth Muscle Circulation Research. 84: 536-542. PMID 10082475 DOI: 10.1161/01.Res.84.5.536  0.407
1998 Lesh RE, Nixon GF, Fleischer S, Airey JA, Somlyo AP, Somlyo AV. Localization of ryanodine receptors in smooth muscle Circulation Research. 82: 175-185. PMID 9468188 DOI: 10.1161/01.Res.82.2.175  0.432
1997 Bruce L, Nixon GF. Increased sensitization of the myofilaments in rat neonatal portal vein: a potential mechanism Experimental Physiology. 82: 985-993. PMID 9413730 DOI: 10.1113/Expphysiol.1997.Sp004084  0.406
1996 Gong MC, Iizuka K, Nixon G, Browne JP, Hall A, Eccleston JF, Sugai M, Kobayashi S, Somlyo AV, Somlyo AP. Role of guanine nucleotide-binding proteins--ras-family or trimeric proteins or both--in Ca2+ sensitization of smooth muscle. Proceedings of the National Academy of Sciences of the United States of America. 93: 1340-5. PMID 8577766 DOI: 10.1073/Pnas.93.3.1340  0.447
1995 Nixon GF, Iizuka K, Haystead CMM, Haystead TAJ, Somlyo AP, Somlyo AV. Phosphorylation of caldesmon by mitogen-activated protein kinase with no effort on Ca2+ sensitivity in rabbit smooth muscle Journal of Physiology. 487: 283-289. PMID 8558463 DOI: 10.1113/Jphysiol.1995.Sp020879  0.463
1995 Nixon GF, Pyne NJ, Wadsworth RM, Hamilton CA, Reid JL. Pertussis toxin sensitive endothelin-1 coupling to inositol phosphate formation via a gtp-binding protein: Comparison in shr and wky cultured aortic smooth muscle cells Clinical and Experimental Hypertension. 17: 507-522. PMID 7613525 DOI: 10.3109/10641969509037421  0.402
1994 Nixon GF, Mignery GA, Somlyo AV. Immunogold localization of inositol 1,4,5-trisphosphate receptors and characterization of ultrastructural features of the sarcoplasmic reticulum in phasic and tonic smooth muscle Journal of Muscle Research and Cell Motility. 15: 682-700. PMID 7706424 DOI: 10.1007/Bf00121075  0.419
1993 Nixon GF, Hamilton CA, Wadsworth RM, Reid JL. Comparison of Endothelin-1 and Noradrenaline Stimulated Inositol Phosphate Formation in Cultured Aortic Smooth Muscle Cells From Spontaneously Hypertensive and Wistar Kyoto Rats Blood Pressure. 2: 221-227. PMID 8205317 DOI: 10.3109/08037059309077555  0.397
1990 Nixon GF, Hamilton CA, Wadsworth RM, Reid JL. Inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension. Journal of Hypertension. 8: 1155-1160. PMID 1962806 DOI: 10.1097/00004872-199012000-00013  0.356
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