Thomas K. Henthorn, M.D. - Publications

Affiliations: 
Anesthesiology Northwestern University Feinberg School of Medicine, Chicago, IL, United States 

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Henthorn TK, Krejcie TC, Avram MJ. Elimination Clearance of Dexmedetomidine: Cross-examining What the Data Say. Anesthesiology. 136: 258-260. PMID 34965290 DOI: 10.1097/ALN.0000000000004087  0.427
2019 Sempio C, Huestis MA, Mikulich-Gilbertson SK, Klawitter J, Christians U, Henthorn TK. Population Pharmacokinetic Modeling of Plasma Δ -tetrahydrocannabinol and an Active and Inactive Metabolite Following Controlled Smoked Cannabis Administration. British Journal of Clinical Pharmacology. PMID 31747464 DOI: 10.1111/Bcp.14170  0.317
2019 Peterson MB, Cohen MN, O'Neill BR, Garg S, Child J, Henthorn TK, Galinkin JG. Preoperative Vancomycin Administration for Surgical Site Prophylaxis: Plasma and Soft-Tissue Concentrations in Pediatric Neurosurgical and Orthopedic Patients. Anesthesia and Analgesia. PMID 31397701 DOI: 10.1213/Ane.0000000000004340  0.306
2018 Henthorn TK, Avram MJ, Dahan A, Gustafsson LL, Persson J, Krejcie TC, Olofsen E. Combined Recirculatory-compartmental Population Pharmacokinetic Modeling of Arterial and Venous Plasma S(+) and R(-) Ketamine Concentrations. Anesthesiology. PMID 29771709 DOI: 10.1097/Aln.0000000000002265  0.581
2017 McLay JS, Engelhardt T, Mohammed BS, Cameron G, Cohen MN, Galinkin JL, Christians U, Avram MJ, Henthorn TK, Dsida RM, Anderson BJ. The pharmacokinetics of intravenous ketorolac in children aged 2 months to 16 years: A population analysis. Paediatric Anaesthesia. PMID 29266539 DOI: 10.1111/Pan.13302  0.508
2017 Jonkman K, Duma A, Olofsen E, Henthorn T, van Velzen M, Mooren R, Siebers L, van den Beukel J, Aarts L, Niesters M, Dahan A. Pharmacokinetics and Bioavailability of Inhaled Esketamine in Healthy Volunteers. Anesthesiology. 127: 675-683. PMID 28759464 DOI: 10.1097/Aln.0000000000001798  0.347
2011 Cohen MN, Christians U, Henthorn T, Vu Tran Z, Moll V, Zuk J, Galinkin J. Pharmacokinetics of single-dose intravenous ketorolac in infants aged 2-11 months. Anesthesia and Analgesia. 112: 655-60. PMID 21233498 DOI: 10.1213/Ane.0B013E3182075D04  0.341
2009 Elkiweri IA, Zhang YL, Christians U, Ng KY, Tissot van Patot MC, Henthorn TK. Competitive substrates for P-glycoprotein and organic anion protein transporters differentially reduce blood organ transport of fentanyl and loperamide: pharmacokinetics and pharmacodynamics in Sprague-Dawley rats. Anesthesia and Analgesia. 108: 149-59. PMID 19095843 DOI: 10.1213/Ane.0B013E31818E0Bd1  0.302
2008 Avram MJ, Spyker DA, Henthorn TK, Cassella JV. The pharmacokinetics and bioavailability of prochlorperazine delivered as a thermally generated aerosol in a single breath to volunteers. Clinical Pharmacology and Therapeutics. 85: 71-7. PMID 18830225 DOI: 10.1038/Clpt.2008.184  0.611
2008 Henthorn TK, Krejcie TC, Avram MJ. Early drug distribution: a generally neglected aspect of pharmacokinetics of particular relevance to intravenously administered anesthetic agents. Clinical Pharmacology and Therapeutics. 84: 18-22. PMID 18563069 DOI: 10.1038/Clpt.2008.107  0.592
2008 Henthorn TK. The effect of altered physiological states on intravenous anesthetics. Handbook of Experimental Pharmacology. 363-77. PMID 18175100 DOI: 10.1007/978-3-540-74806-9_17  0.38
2007 Avram MJ, Henthorn TK, Spyker DA, Krejcie TC, Lloyd PM, Cassella JV, Rabinowitz JD. Recirculatory pharmacokinetic model of the uptake, distribution, and bioavailability of prochlorperazine administered as a thermally generated aerosol in a single breath to dogs. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 262-7. PMID 17079359 DOI: 10.1124/Dmd.106.010652  0.613
2004 Avram MJ, Krejcie TC, Henthorn TK, Niemann CU. Beta-adrenergic blockade affects initial drug distribution due to decreased cardiac output and altered blood flow distribution. The Journal of Pharmacology and Experimental Therapeutics. 311: 617-24. PMID 15197245 DOI: 10.1124/Jpet.104.070094  0.606
2003 Minto CF, Schnider TW, Gregg KM, Henthorn TK, Shafer SL. Using the time of maximum effect site concentration to combine pharmacokinetics and pharmacodynamics Anesthesiology. 99: 324-333. PMID 12883405 DOI: 10.1097/00000542-200308000-00014  0.327
2002 Cho CW, Liu Y, Cobb WN, Henthorn TK, Lillehei K, Christians U, Ng KY. Ultrasound-induced mild hyperthermia as a novel approach to increase drug uptake in brain microvessel endothelial cells. Pharmaceutical Research. 19: 1123-9. PMID 12240937 DOI: 10.1023/A:1019837923906  0.305
2002 Avram MJ, Krejcie TC, Henthorn TK. The concordance of early antipyrine and thiopental distribution kinetics. The Journal of Pharmacology and Experimental Therapeutics. 302: 594-600. PMID 12130720 DOI: 10.1124/Jpet.102.034611  0.603
2001 Birmingham PK, Tobin MJ, Fisher DM, Henthorn TK, Hall SC, Coté CJ. Initial and subsequent dosing of rectal acetaminophen in children: a 24-hour pharmacokinetic study of new dose recommendations. Anesthesiology. 94: 385-9. PMID 11374595 DOI: 10.1097/00000542-200103000-00005  0.324
2000 Avram MJ, Krejcie TC, Niemann CU, Enders-Klein C, Shanks CA, Henthorn TK. Isoflurane alters the recirculatory pharmacokinetics of physiologic markers. Anesthesiology. 92: 1757-68. PMID 10839928 DOI: 10.1097/00000542-200006000-00036  0.573
2000 Niemann CU, Henthorn TK, Krejcie TC, Shanks CA, Enders-Klein C, Avram MJ. Indocyanine green kinetics characterize blood volume and flow distribution and their alteration by propranolol. Clinical Pharmacology and Therapeutics. 67: 342-50. PMID 10801242 DOI: 10.1067/Mcp.2000.104945  0.562
1999 Henthorn TK, Krejcie TC, Niemann CU, Enders-Klein C, Shanks CA, Avram MJ. Ketamine distribution described by a recirculatory pharmacokinetic model is not stereoselective. Anesthesiology. 91: 1733-43. PMID 10598617 DOI: 10.1097/00000542-199912000-00027  0.57
1999 Kaplan B, Wang Z, Siddhom O, Henthorn TK, Mujais SK. Evaluation of urea kinetics utilizing stable isotope urea and pharmacokinetic modeling. Artificial Organs. 23: 44-50. PMID 9950178 DOI: 10.1046/J.1525-1594.1999.06290.X  0.311
1998 Dsida RM, Wheeler M, Birmingham PK, Henthorn TK, Avram MJ, Enders-Klein C, Maddalozzo J, Coté CJ. Premedication of pediatric tonsillectomy patients with oral transmucosal fentanyl citrate. Anesthesia and Analgesia. 86: 66-70. PMID 9428853 DOI: 10.1097/00000539-199801000-00013  0.525
1998 Avram MJ, Krejcie TC, Niemann CU, Klein C, Gentry WB, Shanks CA, Henthorn TK. The effect of halothane on the recirculatory pharmacokinetics of physiologic markers. Anesthesiology. 87: 1381-93. PMID 9416724 DOI: 10.1097/00000542-199712000-00018  0.575
1998 Krejcie TC, Avram MJ, Gentry WB, Niemann CU, Janowski MP, Henthorn TK. A recirculatory model of the pulmonary uptake and pharmacokinetics of lidocaine based on analysis of arterial and mixed venous data from dogs. Journal of Pharmacokinetics and Biopharmaceutics. 25: 169-90. PMID 9408858 DOI: 10.1023/A:1025780012960  0.591
1998 Krejcie TC, Henthorn TK, Niemann CU, Klein C, Shanks CA, Avram MJ. THE EFFECT OF ISOFLURANE ON DRUG DISPOSITION FROM THE MOMENT OF INJECTION Anesthesiology. 89: 520A. DOI: 10.1097/00000542-199809090-00039  0.558
1998 Krejcie TC, Avram MJ, Henthorn TK, Waters CM. Fentanyl Uptake by Pulmonary Endothelium Anesthesiology. 89: 519A. DOI: 10.1097/00000542-199809090-00038  0.494
1997 Birmingham PK, Tobin MJ, Henthorn TK, Fisher DM, Berkelhamer MC, Smith FA, Fanta KB, Coté CJ. Twenty-four-hour pharmacokinetics of rectal acetaminophen in children: an old drug with new recommendations. Anesthesiology. 87: 244-52. PMID 9286887 DOI: 10.1097/00000542-199708000-00010  0.32
1997 Dsida R, Wheeler M, Birmingham P, Wang Z, Avram M, Henthorn T, Kennedy-Mooney S, Cote C. A1055 Developmental Pharmacokinetics of Intravenous Ketorolac in Pediatric Surgical Patients Anesthesiology. 87: 1055A. DOI: 10.1097/00000542-199709001-01055  0.515
1997 Krejcie T, Henthorn T, Niemann C, Klein C, Shanks C, Avram M. A351 THE EFFECT OF BLOOD VOLUME ON DRUG DISPOSITION FROM THE MOMENT OF INJECTION Anesthesiology. 87: 351A. DOI: 10.1097/00000542-199709001-00351  0.571
1997 Niemann C, Krejcie T, Henthorn T, Klein C, Avram M. A330 REGIONAL BLOOD FLOWS AND VOLUMES ARE NOT PROPORTIONAL TO CARDIAC INDEX IN MAN Anesthesiology. 87: 330A. DOI: 10.1097/00000542-199709001-00330  0.528
1996 Krejcie TC, Jacquez JA, Avram MJ, Niemann CU, Shanks CA, Henthorn TK. Use of parallel Erlang density functions to analyze first-pass pulmonary uptake of multiple indicators in dogs. Journal of Pharmacokinetics and Biopharmaceutics. 24: 569-88. PMID 9300351 DOI: 10.1007/Bf02353481  0.567
1996 Krejcie TC, Henthorn TK, Niemann CU, Klein C, Gupta DK, Gentry WB, Shanks CA, Avram MJ. Recirculatory pharmacokinetic models of markers of blood, extracellular fluid and total body water administered concomitantly. The Journal of Pharmacology and Experimental Therapeutics. 278: 1050-7. PMID 8819485  0.615
1996 Niemann C, Krejcie T, Henthorn T, Avram M. Characterization of Lagged Concentration-Time Data by an Erlang Distribution Function Clinical Pharmacology & Therapeutics. 59: 206-206. DOI: 10.1038/Sj.Clpt.1996.323  0.527
1995 Shanks CA, Avram MJ, Krejcie TC, Henthorn TK. Calculation of an effect compartment rate constant using recovery indices obtained with an isolated arm technique. British Journal of Anaesthesia. 75: 109-12. PMID 7669449 DOI: 10.1093/Bja/75.1.109  0.508
1994 Shanks CA, Avram MJ, Krejcie TC, Henthorn TK, Gentry WB. A pharmacokinetic-pharmacodynamic model for quantal responses with thiopental. Journal of Pharmacokinetics and Biopharmaceutics. 21: 309-21. PMID 8258770 DOI: 10.1007/Bf01059782  0.581
1994 Gentry WB, Krejcie TC, Henthorn TK, Shanks CA, Howard KA, Gupta DK, Avram MJ. Effect of infusion rate on thiopental dose-response relationships. Assessment of a pharmacokinetic-pharmacodynamic model. Anesthesiology. 81: 316-24; discussion 2. PMID 8053580 DOI: 10.1097/00000542-199408000-00002  0.579
1994 Gupta DK, Henthorn TK. Association of University Anesthesiologists Satellite Symposium: Pharmacokinetics and Pharmacodynamics Anesthesiology. 81: 1556. DOI: 10.1097/00000542-199412000-00042  0.397
1994 Henthorn TK, Krejcie TC, Gentry WB, Avram MJ. THE PULMONARY UPTAKE OF ALFENTANIL AND FENTANYL DEFINED IN A RECIRCULATORY MODEL Anesthesiology. 81: A412. DOI: 10.1097/00000542-199409001-00411  0.518
1993 Avram MJ, Sanghvi R, Henthorn TK, Krejcie TC, Shanks CA, Fragen RJ, Howard KA, Kaczynski DA. Determinants of thiopental induction dose requirements. Anesthesia and Analgesia. 76: 10-7. PMID 8418708 DOI: 10.1213/00000539-199301000-00003  0.536
1993 HENTHORN TK, KREJCIE TC, AVRAM MJ. The Relationship Between Alfentanil Distribution Kinetics and Cardiac Output Survey of Anesthesiology. 37: 199. DOI: 10.1097/00132586-199308000-00021  0.471
1993 Henthorn TK. Pharmacokinetics for Anaesthesia Anesthesiology. 78: 624. DOI: 10.1097/00000542-199303000-00055  0.366
1992 Henthorn TK, Avram MJ, Krejcie TC, Shanks CA, Asada A, Kaczynski DA. Minimal compartmental model of circulatory mixing of indocyanine green. The American Journal of Physiology. 262: H903-10. PMID 1558199 DOI: 10.1152/Ajpheart.1992.262.3.H903  0.595
1992 Henthorn TK, Krejcie TC, Avram MJ. The relationship between alfentanil distribution kinetics and cardiac output. Clinical Pharmacology and Therapeutics. 52: 190-6. PMID 1505154 DOI: 10.1097/00132586-199308000-00021  0.582
1992 Henthorn TK, Krejcie TC, Shanks CA, Avram MJ. Time-dependent distribution volume and kinetics of the pharmacodynamic effector site. Journal of Pharmaceutical Sciences. 81: 1136-8. PMID 1447720 DOI: 10.1002/Jps.2600811119  0.527
1992 Krejcie TC, Sanghvi R, Henthorn TK, Shanks CA, Fragen RJ, Howard K, Kaczynski D, Avram MJ. PATIENT CHARACTERISTICS INCLUDED IN MODELS FOR THIOPENTAL DOSES AT CLINICAL AND EEG INDUCTION ENDPOINTS Anesthesiology. 77: A450. DOI: 10.1097/00000542-199209001-00450  0.527
1991 Avram MJ, Sanghvi R, Henthorn TK, Fragen RJ, Asada A, Pemberton D, Correll T, Minieka I. THE PHARMACOKINETICS OF ALFENTANIL ADMINISTERED BY MULTIPLE BOLUS AND CONTINUOUS INFUSION IN THE PRESENCE OP EITHER NITROUS OXIDE OR PROPOFOL Anesthesiology. 75: A320. DOI: 10.1097/00000542-199109001-00320  0.531
1991 Henthorn TK, Avram MJ. Pharmacokinetic and pharmacodynamic principles BaillièRe's Clinical Anaesthesiology. 5: 489-511. DOI: 10.1016/S0950-3501(05)80041-8  0.599
1990 Avram MJ, Krejcie TC, Henthorn TK. The relationship of age to the pharmacokinetics of early drug distribution: the concurrent disposition of thiopental and indocyanine green. Anesthesiology. 72: 403-11. PMID 2310019 DOI: 10.1097/00000542-199003000-00002  0.61
1990 Fragen RJ, Avram MJ, Henthorn TK, Asada A, Pemberton D, Correll T. TOTAL INTRAVENOUS ANESTHESIA WITH PROPOFOL ALFENTANIL, AND VECURONIUM FOR SUPERFICIAL SURGERY. Anesthesia & Analgesia. 70: S112. DOI: 10.1213/00000539-199002001-00112  0.503
1990 Henthorn TK, Avram MJ. Pharmacokinetics and pharmacodynamics of drug response Current Opinion in Anaesthesiology. 3: 529-537. DOI: 10.1097/00001503-199003040-00002  0.503
1990 Krejcie TC, Henthorn TK, Shanks CA, Asada A, Kaozynski DA, Avram MJ. A380 THE INTRAVASCULAR DISPOSITION OF INDOCYANINE GREEN (ICG) FROM THE MOMENT OF ITS ADMINISTRATION Anesthesiology. 73: NA. DOI: 10.1097/00000542-199009001-00377  0.506
1990 Shanks CA, Henthorn TK, Kaozynski DA, Asada A, Krejoie TC, Avram MJ. A377 A PHARMACOKINETIC MODEL CHARACTERIZING ANTIPYRINE DISPOSITION FROM THE MOMENT OP ITS ADMINISTRATION Anesthesiology. 73: NA. DOI: 10.1097/00000542-199009001-00374  0.538
1989 Henthorn TK, Benitez J, Avram MJ, Martinez C, Llerena A, Cobaleda J, Krejcie TC, Gibbons RD. Assessment of the debrisoquin and dextromethorphan phenotyping tests by gaussian mixture distributions analysis. Clinical Pharmacology and Therapeutics. 45: 328-33. PMID 2920506 DOI: 10.1038/Clpt.1989.36  0.514
1989 Henthorn TK, Avram MJ, Krejcie TC. Intravascular mixing and drug distribution: the concurrent disposition of thiopental and indocyanine green. Clinical Pharmacology and Therapeutics. 45: 56-65. PMID 2910638 DOI: 10.1038/Clpt.1989.9  0.593
1989 Henthorn TK, Avram MJ, Krejcie TC. Alfentanil clearance is independent of the polymorphic debrisoquin hydroxylase. Anesthesiology. 71: 635-9. PMID 2817455 DOI: 10.1097/00000542-198911000-00002  0.533
1989 Bertilsson L, Henthorn TK, Sanz E, Tybring G, Säwe J, Villén T. Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquin, hydroxylation phenotype. Clinical Pharmacology and Therapeutics. 45: 348-55. PMID 2495208 DOI: 10.1097/00004714-199002000-00016  0.303
1989 Henthorn TK, Avram MJ, Krejcie TC, Shanks CA. A DELAYED RETURN TO THE CENTRAL COMPARTMENT EXPLAINS OSCILLATION IN THE THIOPENTAL CONCENTRATION-TIME CURVE Anesthesiology. 71: A258. DOI: 10.1097/00000542-198909001-00258  0.512
1989 Krejcie TC, Henthorn TK, Wheeler M, Avram MJ. MODELLING NON-STATIONARY PHARMACOKINETICS DURING CANINE METHOHEXITAL ANESTHESIA Anesthesiology. 71: A257. DOI: 10.1097/00000542-198909001-00257  0.541
1988 Katz JA, Kaeding CS, Hill JR, Henthorn TK. The Pharmacokinetics of Bupivacaine When Injected Intra-articularly After Knee Arthroscopy Anesthesia & Analgesia. 67: 872???875. DOI: 10.1213/00000539-198809000-00014  0.371
1988 Avram MJ, Henthorn TK, Krejcie TC, Benitez J, Gibbons RD, Llerena A, Martinez C, Cobaleda J. THE DEXTROMETHORPHAN PHENOTYPING TEST ACCURATELY PREDICTS DEBRISOQUIN HYDROXYLASE PHENOTYPE Anesthesiology. 69: A422. DOI: 10.1097/00000542-198809010-00421  0.473
1987 Avram MJ, Shanks CA, Henthorn TK, Ronai AK, Kinzer J, Wilkinson CJ. Metocurine kinetics in patients undergoing operations requiring cardiopulmonary bypass. Clinical Pharmacology and Therapeutics. 42: 576-81. PMID 3315392 DOI: 10.1038/Clpt.1987.199  0.557
1987 Krejcie TC, Henthorn TK, Avram MJ, Morton DL. THIOPENTAL KINETICS AND AGE Anesthesiology. 67: A664. DOI: 10.1097/00000542-198709001-00664  0.48
1987 Henthorn TK, Krejcie TC, Avram MJ. AGE AND INTRAVASCULAR MIXING DURING INDUCTION WITH THIOPENTAL Anesthesiology. 67: A663. DOI: 10.1097/00000542-198709001-00663  0.479
1986 Avram MJ, Henthorn TK, Shanks CA, Krejcie TC. The initial rate of change in distribution volume is the sum of intercompartmental clearances. Journal of Pharmaceutical Sciences. 75: 919-20. PMID 3783465 DOI: 10.1002/Jps.2600750922  0.521
1986 Avram MJ, Henthorn TK, Krejcie TC. Assay for serum sufentanil level is not sensitive. Anesthesiology. 65: 110-2. PMID 2942059 DOI: 10.1097/00000542-198607000-00037  0.464
1984 Frederiksen MC, Bowsher DJ, Ruo TI, Henthorn TK, Ts'ao CH, Green D, Atkinson AJ. Kinetics of epsilon-aminocaproic acid distribution, elimination, and antifibrinolytic effects in normal subjects. Clinical Pharmacology and Therapeutics. 35: 387-93. PMID 6697646 DOI: 10.1038/Clpt.1984.48  0.342
1983 Fragen RJ, Avram MJ, Henthorn TK, Caldwell NJ. A Pharmacokinetically Designed Etomidate Infusion Regimen for Hypnosis Anesthesia & Analgesia. 62: 654???660. DOI: 10.1213/00000539-198307000-00006  0.578
1982 Eudeikis JR, Henthorn TK, Lertora JJ, Atkinson AJ, Chao GC, Kushner W. Kinetic analysis of the vasodilator and ganglionic blocking actions of N-acetylprocainamide. Journal of Cardiovascular Pharmacology. 4: 303-9. PMID 6175815 DOI: 10.1097/00005344-198203000-00020  0.337
1982 Shanks CA, Funk DI, Avram MJ, Henthorn TK. Gallamine Administered by Combined Bolus and Infusion Anesthesia & Analgesia. 61: 847???852. DOI: 10.1213/00000539-198210000-00009  0.555
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