| Year |
Citation |
Score |
| 2023 |
Chisholm LO, Orlandi KN, Phillips SR, Shavlik MJ, Harms MJ. Ancestral Reconstruction and the Evolution of Protein Energy Landscapes. Annual Review of Biophysics. PMID 38134334 DOI: 10.1146/annurev-biophys-030722-125440 |
0.414 |
|
| 2022 |
Harman JL, Reardon PN, Costello SM, Warren GD, Phillips SR, Connor PJ, Marqusee S, Harms MJ. Evolution avoids a pathological stabilizing interaction in the immune protein S100A9. Proceedings of the National Academy of Sciences of the United States of America. 119: e2208029119. PMID 36194634 DOI: 10.1073/pnas.2208029119 |
0.374 |
|
| 2021 |
Morrison AJ, Wonderlick DR, Harms MJ. Ensemble epistasis: thermodynamic origins of nonadditivity between mutations. Genetics. 219. PMID 34849909 DOI: 10.1093/genetics/iyab105 |
0.347 |
|
| 2021 |
Jain R, Muneeruddin K, Anderson J, Harms MJ, Shaffer SA, Matthews CR. A conserved folding nucleus sculpts the free energy landscape of bacterial and archaeal orthologs from a divergent TIM barrel family. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33875592 DOI: 10.1073/pnas.2019571118 |
0.343 |
|
| 2021 |
Nixon CF, Lim SA, Sailer ZR, Zheludev IN, Gee CL, Kelch BA, Harms MJ, Marqusee S. Exploring the Evolutionary History of Kinetic Stability in the α-Lytic Protease Family. Biochemistry. PMID 33433210 DOI: 10.1021/acs.biochem.0c00720 |
0.309 |
|
| 2020 |
Harman JL, Loes AN, Warren GD, Heaphy MC, Lampi KJ, Harms MJ. Evolution of multifunctionality through a pleiotropic substitution in the innate immune protein S100A9. Elife. 9. PMID 32255429 DOI: 10.7554/eLife.54100 |
0.346 |
|
| 2019 |
Nixon C, Lim SA, Harms M, Marqusee S. The Effect of Input Set to Consensus Derived Proteins and their Relationship to Ancestral Proteins Biophysical Journal. 116: 335a-336a. DOI: 10.1016/J.Bpj.2018.11.1828 |
0.422 |
|
| 2018 |
Nixon C, Lim SA, Sailer Z, Harms M, Marqusee S. Using Ancestral Proteins to Probe the Thermodynamic and Kinetic Properties of the Alpha-Lytic Protease Family Biophysical Journal. 114: 580a. DOI: 10.1016/J.Bpj.2017.11.3173 |
0.351 |
|
| 2017 |
Sailer ZR, Harms MJ. Molecular ensembles make evolution unpredictable. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078365 DOI: 10.1073/pnas.1711927114 |
0.384 |
|
| 2016 |
Lim SA, Hart KM, Harms MJ, Marqusee S. Evolutionary trend toward kinetic stability in the folding trajectory of RNases H. Proceedings of the National Academy of Sciences of the United States of America. PMID 27799545 DOI: 10.1073/Pnas.1611781113 |
0.393 |
|
| 2016 |
Eick GN, Bridgham JT, Anderson DP, Harms MJ, Thornton JW. Robustness of reconstructed ancestral protein functions to statistical uncertainty. Molecular Biology and Evolution. PMID 27795231 DOI: 10.1093/Molbev/Msw223 |
0.609 |
|
| 2016 |
Wheeler LC, Lim SA, Marqusee S, Harms MJ. The thermostability and specificity of ancient proteins. Current Opinion in Structural Biology. 38: 37-43. PMID 27288744 DOI: 10.1016/J.Sbi.2016.05.015 |
0.42 |
|
| 2016 |
Lim SA, Bolin ER, Harms MJ, Hart KM, Thornton JW, Marqusee S. Ancestral Sequence Reconstruction Reveals the Evolutionary History of the Folding Pathway and Landscape of Ribonucleases H Biophysical Journal. 110: 391a. DOI: 10.1016/J.Bpj.2015.11.2111 |
0.609 |
|
| 2014 |
Hart KM, Harms MJ, Schmidt BH, Elya C, Thornton JW, Marqusee S. Thermodynamic system drift in protein evolution. Plos Biology. 12: e1001994. PMID 25386647 DOI: 10.1371/Journal.Pbio.1001994 |
0.604 |
|
| 2014 |
Harms MJ, Thornton JW. Historical contingency and its biophysical basis in glucocorticoid receptor evolution. Nature. 512: 203-7. PMID 24930765 DOI: 10.1038/Nature13410 |
0.643 |
|
| 2013 |
Harms MJ, Thornton JW. Evolutionary biochemistry: revealing the historical and physical causes of protein properties. Nature Reviews. Genetics. 14: 559-71. PMID 23864121 DOI: 10.1038/Nrg3540 |
0.554 |
|
| 2013 |
Harms MJ, Eick GN, Goswami D, Colucci JK, Griffin PR, Ortlund EA, Thornton JW. Biophysical mechanisms for large-effect mutations in the evolution of steroid hormone receptors. Proceedings of the National Academy of Sciences of the United States of America. 110: 11475-80. PMID 23798447 DOI: 10.1073/Pnas.1303930110 |
0.638 |
|
| 2013 |
Williams SG, Harms MJ, Hall KB. Resurrection of an Urbilaterian U1A/U2B″/SNF protein. Journal of Molecular Biology. 425: 3846-62. PMID 23796518 DOI: 10.1016/J.Jmb.2013.05.031 |
0.35 |
|
| 2012 |
Eick GN, Colucci JK, Harms MJ, Ortlund EA, Thornton JW. Evolution of minimal specificity and promiscuity in steroid hormone receptors. Plos Genetics. 8: e1003072. PMID 23166518 DOI: 10.1371/Journal.Pgen.1003072 |
0.603 |
|
| 2011 |
Schlessman JL, Khangulov VS, Karp DA, Harms MJ, Chimenti MS, Garcia-Moreno E B. Domain Swapping Promoted by Charges in the Hydrophobic Core of a Protein Biophysical Journal. 100: 398a. DOI: 10.1016/J.Bpj.2010.12.2365 |
0.332 |
|
| 2010 |
Bridgham JT, Eick GN, Larroux C, Deshpande K, Harms MJ, Gauthier ME, Ortlund EA, Degnan BM, Thornton JW. Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor. Plos Biology. 8. PMID 20957188 DOI: 10.1371/Journal.Pbio.1000497 |
0.623 |
|
| 2010 |
Harms MJ, Thornton JW. Analyzing protein structure and function using ancestral gene reconstruction. Current Opinion in Structural Biology. 20: 360-6. PMID 20413295 DOI: 10.1016/J.Sbi.2010.03.005 |
0.626 |
|
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