| Year |
Citation |
Score |
| 2020 |
Singh SP, Mishra A, Shyanti RK, Singh RP, Acharya A. Silver Nanoparticles Synthesized Using Carica papaya Leaf Extract (AgNPs-PLE) Causes Cell Cycle Arrest and Apoptosis in Human Prostate (DU145) Cancer Cells. Biological Trace Element Research. PMID 32557113 DOI: 10.1007/S12011-020-02255-Z |
0.354 |
|
| 2020 |
Singh V, Singh R, Kujur PK, Singh RP. Combination of Resveratrol and Quercetin Causes Cell Growth Inhibition, DNA Damage, Cell Cycle Arrest, and Apoptosis in Oral Cancer Cells. Assay and Drug Development Technologies. PMID 32423320 DOI: 10.1089/Adt.2020.972 |
0.362 |
|
| 2019 |
Kumar K, Mishra JN, Singh RP. Usnic acid induces apoptosis in human gastric cancer cells through ROS generation and DNA damage and causes up-regulation of DNA-PKcs and γ-H2A.X phosphorylation. Chemico-Biological Interactions. 108898. PMID 31715134 DOI: 10.1016/J.Cbi.2019.108898 |
0.304 |
|
| 2019 |
Patel R, Varghese JF, Singh RP, Yadav UCS. Induction of endothelial dysfunction by oxidized low-density lipoproteins via downregulation of Erk-5/Mef2c/Klf2 signaling: Amelioration by fisetin. Biochimie. PMID 31199942 DOI: 10.1016/J.Biochi.2019.06.007 |
0.327 |
|
| 2019 |
Vinchure OS, Sharma V, Tabasum S, Ghosh S, Singh RP, Sarkar C, Kulshreshtha R. Polycomb complex mediated epigenetic reprogramming alters TGF-β signaling via a novel EZH2/miR-490/TGIF2 axis thereby inducing migration and EMT potential in glioblastomas. International Journal of Cancer. PMID 31008529 DOI: 10.1002/Ijc.32360 |
0.302 |
|
| 2019 |
Tak J, Sabarwal A, Shyanti RK, Singh RP. Berberine enhances posttranslational protein stability of p21/cip1 in breast cancer cells via down-regulation of Akt. Molecular and Cellular Biochemistry. PMID 30911957 DOI: 10.1007/S11010-019-03529-4 |
0.338 |
|
| 2019 |
Tabasum S, Singh RP. Fisetin suppresses migration, invasion and stem-cell-like phenotype of human non-small cell lung carcinoma cells via attenuation of epithelial to mesenchymal transition. Chemico-Biological Interactions. PMID 30802432 DOI: 10.1016/J.Cbi.2019.02.020 |
0.315 |
|
| 2019 |
Singh SP, Mathan SV, Dheeraj A, Tailor D, Singh RP, Acharya A. Abstract 3004: Anticancer effects and associated molecular changes ofCarica papayaagainst prostate cancer Cancer Research. 79: 3004-3004. DOI: 10.1158/1538-7445.Am2019-3004 |
0.356 |
|
| 2018 |
Kumar K, Sabarwal A, Singh RP. Mancozeb selectively induces mitochondrial-mediated apoptosis in human gastric carcinoma cells through ROS generation. Mitochondrion. PMID 29902665 DOI: 10.1016/J.Mito.2018.06.003 |
0.349 |
|
| 2018 |
Prasad N, Sabarwal A, Yadav UCS, Singh RP. Lupeol induces S-phase arrest and mitochondria-mediated apoptosis in cervical cancer cells. Journal of Biosciences. 43: 249-261. PMID 29872014 DOI: 10.1007/S12038-018-9743-8 |
0.36 |
|
| 2018 |
Singh C, Shyanti RK, Singh V, Kale RK, Mishra JPN, Singh RP. Integrin expression and glycosylation patterns regulate cell-matrix adhesion and alter with breast cancer progression. Biochemical and Biophysical Research Communications. PMID 29577899 DOI: 10.1016/J.Bbrc.2018.03.169 |
0.306 |
|
| 2018 |
Yadav S, Kujur PK, Pandey SK, Goel Y, Maurya BN, Verma A, Kumar A, Singh RP, Singh SM. Antitumor action of 3-bromopyruvate implicates reorganized tumor growth regulatory components of tumor milieu, cell cycle arrest and induction of mitochondria-dependent tumor cell death. Toxicology and Applied Pharmacology. 339: 52-64. PMID 29221953 DOI: 10.1016/J.Taap.2017.12.004 |
0.302 |
|
| 2018 |
Dheeraj A, Tailor D, Deep G, Singh RP. Abstract 1095: Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) regulates mitochondrial dynamics, EMT and angiogenesis in progression of prostate cancer Cancer Research. 78: 1095-1095. DOI: 10.1158/1538-7445.Am2018-1095 |
0.36 |
|
| 2018 |
Mathan S, Singh S, Singh RP. Abstract B042: Anticancer effects of processed garlic constituent diallyl trisulfide on head and neck squamous cell carcinoma Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B042 |
0.374 |
|
| 2017 |
Saint M, Sawhney S, Sinha I, Singh RP, Dahiya R, Thakur A, Siddharthan R, Natarajan K. Correction for Saint et al., "The TAF9 C-Terminal Conserved Region Domain Is Required for SAGA and TFIID Promoter Occupancy To Promote Transcriptional Activation". Molecular and Cellular Biology. 37. PMID 28710119 DOI: 10.1128/Mcb.00212-17 |
0.655 |
|
| 2017 |
Shyanti RK, Sehrawat A, Singh SV, Mishra JPN, Singh RP. Zerumbone modulates CD1d expression and lipid antigen presentation pathway in breast cancer cells. Toxicology in Vitro : An International Journal Published in Association With Bibra. PMID 28633979 DOI: 10.1016/J.Tiv.2017.06.016 |
0.326 |
|
| 2017 |
Yadav S, Pandey SK, Kumar A, Kujur PK, Singh RP, Singh SM. Antitumor and chemosensitizing action of 3-bromopyruvate: Implication of deregulated metabolism. Chemico-Biological Interactions. PMID 28433571 DOI: 10.1016/J.Cbi.2017.04.015 |
0.336 |
|
| 2016 |
Mohan V, Agarwal R, Singh RP. A novel alkaloid, evodiamine causes nuclear localization of cytochrome-c and induces apoptosis independent of p53 in human lung cancer cells. Biochemical and Biophysical Research Communications. PMID 27402273 DOI: 10.1016/J.Bbrc.2016.07.037 |
0.359 |
|
| 2016 |
Sehrawat A, Croix CS, Baty CJ, Watkins S, Tailor D, Singh RP, Singh SV. Inhibition of mitochondrial fusion is an early and critical event in breast cancer cell apoptosis by dietary chemopreventative benzyl isothiocyanate. Mitochondrion. PMID 27374852 DOI: 10.1016/J.Mito.2016.06.006 |
0.329 |
|
| 2016 |
Sabarwal A, Agarwal R, Singh RP. Fisetin inhibits cellular proliferation and induces mitochondria-dependent apoptosis in human gastric cancer cells. Molecular Carcinogenesis. PMID 27254419 DOI: 10.1002/Mc.22512 |
0.343 |
|
| 2015 |
Nambiar D, Rajamani P, Deep G, Jain AK, Agarwal R, Singh RP. Silibinin preferentially radiosensitizes prostate cancer by inhibiting DNA repair signaling. Molecular Cancer Therapeutics. PMID 26516160 DOI: 10.1158/1535-7163.Mct-15-0348 |
0.329 |
|
| 2015 |
Schlaepfer IR, Nambiar DK, Ramteke A, Kumar R, Dhar D, Agarwal C, Bergman B, Graner M, Maroni P, Singh RP, Agarwal R, Deep G. Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation. Oncotarget. PMID 26087400 DOI: 10.18632/Oncotarget.4479 |
0.347 |
|
| 2015 |
Prajapati V, Kale RK, Singh RP. Silibinin combination with arsenic strongly inhibits survival and invasiveness of human prostate carcinoma cells. Nutrition and Cancer. 67: 647-58. PMID 25868784 DOI: 10.1080/01635581.2015.1019635 |
0.357 |
|
| 2015 |
Nambiar DK, Rajamani P, Singh RP. Silibinin attenuates ionizing radiation-induced pro-angiogenic response and EMT in prostate cancer cells. Biochemical and Biophysical Research Communications. 456: 262-8. PMID 25446081 DOI: 10.1016/J.Bbrc.2014.11.069 |
0.358 |
|
| 2015 |
Kujur PK, Yim D, Singh RP. Abstract 4645: Decursin, a coumarin compound, inhibits the growth of human hepatoma cells involving cell cycle arrest, apoptosis, and autophagy Cancer Research. 75: 4645-4645. DOI: 10.1158/1538-7445.Am2015-4645 |
0.376 |
|
| 2015 |
Nambiar DK, Rajamani P, Jain A, Deep G, Agarwal R, Singh RP. Abstract 3339: Silibinin improves radiotherapeutic efficacy in prostate cancer by reducing IR-induced toxicity and EMT Cancer Research. 75: 3339-3339. DOI: 10.1158/1538-7445.Am2015-3339 |
0.377 |
|
| 2015 |
Tailor DM, Hahm ER, Singh SV, Singh RP. Abstract 1891: Butyric acid reverts DRP1-mediated cell proliferation and migration in colorectal cancer cells Cancer Research. 75: 1891-1891. DOI: 10.1158/1538-7445.Am2015-1891 |
0.377 |
|
| 2014 |
Nambiar DK, Deep G, Singh RP, Agarwal C, Agarwal R. Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1. Oncotarget. 5: 10017-33. PMID 25294820 DOI: 10.18632/Oncotarget.2488 |
0.34 |
|
| 2014 |
Saint M, Sawhney S, Sinha I, Singh RP, Dahiya R, Thakur A, Siddharthan R, Natarajan K. The TAF9 C-terminal conserved region domain is required for SAGA and TFIID promoter occupancy to promote transcriptional activation. Molecular and Cellular Biology. 34: 1547-63. PMID 24550006 DOI: 10.1128/Mcb.01060-13 |
0.667 |
|
| 2014 |
Tailor D, Hahm ER, Kale RK, Singh SV, Singh RP. Sodium butyrate induces DRP1-mediated mitochondrial fusion and apoptosis in human colorectal cancer cells. Mitochondrion. 16: 55-64. PMID 24177748 DOI: 10.1016/J.Mito.2013.10.004 |
0.351 |
|
| 2014 |
Mittal A, Tabasum S, Singh RP. Berberine in combination with doxorubicin suppresses growth of murine melanoma B16F10 cells in culture and xenograft. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 21: 340-7. PMID 24176840 DOI: 10.1016/J.Phymed.2013.09.002 |
0.342 |
|
| 2014 |
Nambiar DK, Rajamani P, Singh RP. Abstract 845: Silibinin radiosensitizes prostate cancer cells by enhancing radiation-induced cell death and inhibiting nuclear EGFR-mediated DNA repair Cancer Research. 74: 845-845. DOI: 10.1158/1538-7445.Am2014-845 |
0.34 |
|
| 2014 |
Nambiar DK, Deep G, Singh RP, Agarwal C, Agarwal R. Abstract 2452: Silibinin inhibits lipid metabolism by primarily targeting the master regulator sterol response element binding protein 1 (SREBP1) in prostate cancer cells Cancer Research. 74: 2452-2452. DOI: 10.1158/1538-7445.Am2014-2452 |
0.37 |
|
| 2013 |
Bhat TA, Nambiar D, Tailor D, Pal A, Agarwal R, Singh RP. Acacetin inhibits in vitro and in vivo angiogenesis and downregulates Stat signaling and VEGF expression Cancer Prevention Research. 6: 1128-1139. PMID 23943785 DOI: 10.1158/1940-6207.Capr-13-0209 |
0.336 |
|
| 2013 |
Singh N, Nambiar D, Kale RK, Singh RP. Usnic acid inhibits growth and induces cell cycle arrest and apoptosis in human lung carcinoma A549 cells. Nutrition and Cancer. 65: 36-43. PMID 23682781 DOI: 10.1080/01635581.2013.785007 |
0.338 |
|
| 2013 |
Nambiar D, Prajapati V, Agarwal R, Singh RP. In vitro and in vivo anticancer efficacy of silibinin against human pancreatic cancer BxPC-3 and PANC-1 cells Cancer Letters. 334: 109-117. PMID 23022268 DOI: 10.1016/J.Canlet.2012.09.004 |
0.359 |
|
| 2012 |
Bhat TA, Nambiar D, Pal A, Agarwal R, Singh RP. Fisetin inhibits various attributes of angiogenesis in vitro and in vivo-implications for angioprevention Carcinogenesis. 33: 385-393. PMID 22139440 DOI: 10.1093/Carcin/Bgr282 |
0.343 |
|
| 2012 |
Tyagi A, Agarwal C, Dwyer-Nield LD, Singh RP, Malkinson AM, Agarwal R. Silibinin modulates TNF-α and IFN-γ mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells. Molecular Carcinogenesis. 51: 832-42. PMID 21882257 DOI: 10.1002/Mc.20851 |
0.34 |
|
| 2011 |
Nambiar D, Rajamani P, Singh RP. Effects of phytochemicals on ionization radiation-mediated carcinogenesis and cancer therapy Mutation Research - Reviews in Mutation Research. 728: 139-157. PMID 22030216 DOI: 10.1016/J.Mrrev.2011.07.005 |
0.327 |
|
| 2011 |
Singh RP, Prasad HK, Sinha I, Agarwal N, Natarajan K. Cap2-HAP complex is a critical transcriptional regulator that has dual but contrasting roles in regulation of iron homeostasis in Candida albicans. The Journal of Biological Chemistry. 286: 25154-70. PMID 21592964 DOI: 10.1074/Jbc.M111.233569 |
0.706 |
|
| 2011 |
Kaur M, Tyagi A, Singh RP, Sclafani RA, Agarwal R, Agarwal C. Grape seed extract upregulates p21 (Cip1) through redox-mediated activation of ERK1/2 and posttranscriptional regulation leading to cell cycle arrest in colon carcinoma HT29 cells. Molecular Carcinogenesis. 50: 553-62. PMID 21268136 DOI: 10.1002/Mc.20739 |
0.372 |
|
| 2010 |
Velmurugan B, Singh RP, Agarwal R, Agarwal C. Dietary-feeding of grape seed extract prevents azoxymethane-induced colonic aberrant crypt foci formation in fischer 344 rats. Molecular Carcinogenesis. 49: 641-52. PMID 20564341 DOI: 10.1002/Mc.20643 |
0.309 |
|
| 2010 |
Kaur M, Velmurugan B, Tyagi A, Agarwal C, Singh RP, Agarwal R. Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling. Neoplasia (New York, N.Y.). 12: 415-24. PMID 20454513 DOI: 10.1593/Neo.10188 |
0.319 |
|
| 2010 |
Rajamanickam S, Velmurugan B, Kaur M, Singh RP, Agarwal R. Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin. Cancer Research. 70: 2368-78. PMID 20215518 DOI: 10.1158/0008-5472.Can-09-3249 |
0.311 |
|
| 2010 |
Velmurugan B, Singh RP, Kaul N, Agarwal R, Agarwal C. Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ mice. Neoplasia (New York, N.Y.). 12: 95-102. PMID 20072658 DOI: 10.1593/Neo.91718 |
0.318 |
|
| 2010 |
Mateen S, Tyagi A, Agarwal C, Singh RP, Agarwal R. Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators. Molecular Carcinogenesis. 49: 247-58. PMID 19908243 DOI: 10.1002/Mc.20595 |
0.347 |
|
| 2010 |
Singh RP, Bhat TA, Nambiar D, Balaiya V, Agarwal R. Abstract LB-428: Decursin inhibits advanced human prostate tumor xenograft growth involving antiproliferative and antiangiogenic mechanisms Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-428 |
0.36 |
|
| 2009 |
Kang TJ, Lee SY, Singh RP, Agarwal R, Yim DS. Anti-tumor activity of oxypeucedanin from Ostericum koreanum against human prostate carcinoma DU145 cells. Acta Oncologica (Stockholm, Sweden). 48: 895-900. PMID 19322700 DOI: 10.1080/02841860902824925 |
0.355 |
|
| 2009 |
Roy S, Gu M, Ramasamy K, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R. p21/Cip1 and p27/Kip1 Are essential molecular targets of inositol hexaphosphate for its antitumor efficacy against prostate cancer. Cancer Research. 69: 1166-73. PMID 19176374 DOI: 10.1158/0008-5472.Can-08-3115 |
0.318 |
|
| 2009 |
Singh RP, Raina K, Deep G, Chan D, Agarwal R. Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 613-21. PMID 19147767 DOI: 10.1158/1078-0432.Ccr-08-1846 |
0.322 |
|
| 2009 |
Tyagi A, Singh RP, Ramasamy K, Raina K, Redente EF, Dwyer-Nield LD, Radcliffe RA, Malkinson AM, Agarwal R. Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3. Cancer Prevention Research (Philadelphia, Pa.). 2: 74-83. PMID 19139021 DOI: 10.1158/1940-6207.Capr-08-0095 |
0.339 |
|
| 2008 |
Velmurugan B, Singh RP, Tyagi A, Agarwal R. Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats. Cancer Prevention Research (Philadelphia, Pa.). 1: 376-84. PMID 19138982 DOI: 10.1158/1940-6207.Capr-08-0059 |
0.328 |
|
| 2008 |
Deep G, Raina K, Singh RP, Oberlies NH, Kroll DJ, Agarwal R. Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: comparison with silymarin and silibinin. International Journal of Cancer. 123: 2750-8. PMID 18798272 DOI: 10.1002/Ijc.23879 |
0.33 |
|
| 2008 |
Chittezhath M, Deep G, Singh RP, Agarwal C, Agarwal R. Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells. Molecular Cancer Therapeutics. 7: 1817-26. PMID 18644994 DOI: 10.1158/1535-7163.Mct-08-0256 |
0.388 |
|
| 2008 |
Singh RP, Gu M, Agarwal R. Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis. Cancer Research. 68: 2043-50. PMID 18339887 DOI: 10.1158/0008-5472.Can-07-6247 |
0.34 |
|
| 2008 |
Singh RP, Tyagi A, Sharma G, Mohan S, Agarwal R. Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 300-8. PMID 18172282 DOI: 10.1158/1078-0432.Ccr-07-1565 |
0.332 |
|
| 2007 |
Tyagi A, Raina K, Singh RP, Gu M, Agarwal C, Harrison G, Glode LM, Agarwal R. Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice. Molecular Cancer Therapeutics. 6: 3248-55. PMID 18089718 DOI: 10.1158/1535-7163.Mct-07-2006 |
0.333 |
|
| 2007 |
Raina K, Blouin MJ, Singh RP, Majeed N, Deep G, Varghese L, Glodé LM, Greenberg NM, Hwang D, Cohen P, Pollak MN, Agarwal R. Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model. Cancer Research. 67: 11083-91. PMID 18006855 DOI: 10.1158/0008-5472.Can-07-2222 |
0.325 |
|
| 2007 |
Singh RP, Deep G, Blouin MJ, Pollak MN, Agarwal R. Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft. Carcinogenesis. 28: 2567-74. PMID 17916909 DOI: 10.1093/Carcin/Bgm218 |
0.339 |
|
| 2007 |
Raina K, Singh RP, Agarwal R, Agarwal C. Oral grape seed extract inhibits prostate tumor growth and progression in TRAMP mice. Cancer Research. 67: 5976-82. PMID 17575168 DOI: 10.1158/0008-5472.Can-07-0295 |
0.315 |
|
| 2007 |
Gu M, Singh RP, Dhanalakshmi S, Agarwal C, Agarwal R. Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice. Cancer Research. 67: 3483-91. PMID 17409458 DOI: 10.1158/0008-5472.Can-06-3955 |
0.375 |
|
| 2006 |
Kaur M, Singh RP, Gu M, Agarwal R, Agarwal C. Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6194-202. PMID 17062697 DOI: 10.1158/1078-0432.Ccr-06-1465 |
0.303 |
|
| 2006 |
Singh RP, Agarwal R. Mechanisms of action of novel agents for prostate cancer chemoprevention. Endocrine-Related Cancer. 13: 751-78. PMID 16954429 DOI: 10.1677/Erc.1.01126 |
0.317 |
|
| 2006 |
Gu M, Singh RP, Dhanalakshmi S, Mohan S, Agarwal R. Differential effect of silibinin on E2F transcription factors and associated biological events in chronically UVB-exposed skin versus tumors in SKH-1 hairless mice. Molecular Cancer Therapeutics. 5: 2121-9. PMID 16928834 DOI: 10.1158/1535-7163.Mct-06-0052 |
0.352 |
|
| 2006 |
Tyagi A, Singh RP, Agarwal C, Agarwal R. Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2. Carcinogenesis. 27: 2269-80. PMID 16777994 DOI: 10.1093/Carcin/Bgl098 |
0.335 |
|
| 2006 |
Singh RP, Dhanalakshmi S, Mohan S, Agarwal C, Agarwal R. Silibinin inhibits UVB- and epidermal growth factor-induced mitogenic and cell survival signaling involving activator protein-1 and nuclear factor-kappaB in mouse epidermal JB6 cells. Molecular Cancer Therapeutics. 5: 1145-53. PMID 16731746 DOI: 10.1158/1535-7163.Mct-05-0478 |
0.381 |
|
| 2006 |
Singh RP, Agarwal R. Prostate cancer chemoprevention by silibinin: bench to bedside. Molecular Carcinogenesis. 45: 436-42. PMID 16637061 DOI: 10.1002/Mc.20223 |
0.335 |
|
| 2006 |
Singh RP, Agarwal R. Natural flavonoids targeting deregulated cell cycle progression in cancer cells. Current Drug Targets. 7: 345-54. PMID 16515531 DOI: 10.2174/138945006776055004 |
0.344 |
|
| 2006 |
Veluri R, Singh RP, Liu Z, Thompson JA, Agarwal R, Agarwal C. Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells. Carcinogenesis. 27: 1445-53. PMID 16474170 DOI: 10.1093/Carcin/Bgi347 |
0.339 |
|
| 2006 |
Deep G, Singh RP, Agarwal C, Kroll DJ, Agarwal R. Silymarin and silibinin cause G1 and G2–M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin Oncogene. 25: 1053-1069. PMID 16205633 DOI: 10.1038/Sj.Onc.1209146 |
0.344 |
|
| 2005 |
Singh RP, Agarwal R. Mechanisms and preclinical efficacy of silibinin in preventing skin cancer. European Journal of Cancer (Oxford, England : 1990). 41: 1969-79. PMID 16084079 DOI: 10.1016/J.Ejca.2005.03.033 |
0.309 |
|
| 2005 |
Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R. Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells. Carcinogenesis. 26: 1978-87. PMID 15975956 DOI: 10.1093/Carcin/Bgi165 |
0.318 |
|
| 2005 |
Gu M, Dhanalakshmi S, Singh RP, Agarwal R. Dietary feeding of silibinin prevents early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 1344-9. PMID 15894701 DOI: 10.1158/1055-9965.Epi-04-0664 |
0.345 |
|
| 2005 |
Padmavathi B, Rath PC, Rao AR, Singh RP. Roots of Withania somnifera Inhibit Forestomach and Skin Carcinogenesis in Mice. Evidence-Based Complementary and Alternative Medicine : Ecam. 2: 99-105. PMID 15841284 DOI: 10.1093/Ecam/Neh064 |
0.322 |
|
| 2005 |
Gu M, Dhanalakshmi S, Mohan S, Singh RP, Agarwal R. Silibinin inhibits ultraviolet B radiation-induced mitogenic and survival signaling, and associated biological responses in SKH-1 mouse skin. Carcinogenesis. 26: 1404-13. PMID 15831527 DOI: 10.1093/Carcin/Bgi096 |
0.338 |
|
| 2005 |
Dhanalakshmi S, Agarwal C, Singh RP, Agarwal R. Silibinin up-regulates DNA-protein kinase-dependent p53 activation to enhance UVB-induced apoptosis in mouse epithelial JB6 cells. The Journal of Biological Chemistry. 280: 20375-83. PMID 15792956 DOI: 10.1074/Jbc.M414640200 |
0.32 |
|
| 2005 |
Padmavathi B, Upreti M, Singh V, Rao AR, Singh RP, Rath PC. Chemoprevention by Hippophae rhamnoides: effects on tumorigenesis, phase II and antioxidant enzymes, and IRF-1 transcription factor. Nutrition and Cancer. 51: 59-67. PMID 15749631 DOI: 10.1207/S15327914Nc5101_9 |
0.339 |
|
| 2005 |
Singh RP, Agrawal P, Yim D, Agarwal C, Agarwal R. Acacetin inhibits cell growth and cell cycle progression, and induces apoptosis in human prostate cancer cells: Structure-activity relationship with linarin and linarin acetate Carcinogenesis. 26: 845-854. PMID 15637089 DOI: 10.1093/Carcin/Bgi014 |
0.359 |
|
| 2005 |
Singh RP, Dhanalakshmi S, Agarwal C, Agarwal R. Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: implications for angioprevention and antiangiogenic therapy. Oncogene. 24: 1188-202. PMID 15558015 DOI: 10.1038/Sj.Onc.1208276 |
0.37 |
|
| 2005 |
Kaur M, Agarwal C, Singh RP, Guan X, Dwivedi C, Agarwal R. Skin cancer chemopreventive agent, {alpha}-santalol, induces apoptotic death of human epidermoid carcinoma A431 cells via caspase activation together with dissipation of mitochondrial membrane potential and cytochrome c release. Carcinogenesis. 26: 369-80. PMID 15528219 DOI: 10.1093/Carcin/Bgh325 |
0.343 |
|
| 2004 |
Singh RP, Mallikarjuna GU, Sharma G, Dhanalakshmi S, Tyagi AK, Chan DC, Agarwal C, Agarwal R. Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8641-7. PMID 15623648 DOI: 10.1158/1078-0432.Ccr-04-1435 |
0.355 |
|
| 2004 |
Agarwal C, Dhanalakshmi S, Singh RP, Agarwal R. Inositol hexaphosphate inhibits growth and induces G1 arrest and apoptotic death of androgen-dependent human prostate carcinoma LNCaP cells. Neoplasia (New York, N.Y.). 6: 646-59. PMID 15548374 DOI: 10.1593/Neo.04232 |
0.386 |
|
| 2004 |
Singh RP, Agarwal R. A cancer chemopreventive agent silibinin, targets mitogenic and survival signaling in prostate cancer. Mutation Research. 555: 21-32. PMID 15476849 DOI: 10.1016/J.Mrfmmm.2004.05.017 |
0.334 |
|
| 2004 |
Mallikarjuna G, Dhanalakshmi S, Singh RP, Agarwal C, Agarwal R. Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling. Cancer Research. 64: 6349-56. PMID 15342425 DOI: 10.1158/0008-5472.Can-04-1632 |
0.349 |
|
| 2004 |
Mohan S, Dhanalakshmi S, Mallikarjuna GU, Singh RP, Agarwal R. Silibinin modulates UVB-induced apoptosis via mitochondrial proteins, caspases activation, and mitogen-activated protein kinase signaling in human epidermoid carcinoma A431 cells. Biochemical and Biophysical Research Communications. 320: 183-9. PMID 15207719 DOI: 10.1016/J.Bbrc.2004.05.153 |
0.345 |
|
| 2004 |
Sharma G, Tyagi AK, Singh RP, Chan DC, Agarwal R. Synergistic anti-cancer effects of grape seed extract and conventional cytotoxic agent doxorubicin against human breast carcinoma cells. Breast Cancer Research and Treatment. 85: 1-12. PMID 15039593 DOI: 10.1023/B:Brea.0000020991.55659.59 |
0.333 |
|
| 2004 |
Dhanalakshmi S, Mallikarjuna GU, Singh RP, Agarwal R. Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis. Carcinogenesis. 25: 1459-65. PMID 15033902 DOI: 10.1093/Carcin/Bgh152 |
0.347 |
|
| 2004 |
Singh RP, Agarwal R. Prostate cancer prevention by silibinin. Current Cancer Drug Targets. 4: 1-11. PMID 14965263 DOI: 10.2174/1568009043481605 |
0.363 |
|
| 2004 |
Singh RP, Tyagi AK, Dhanalakshmi S, Agarwal R, Agarwal C. Grape seed extract inhibits advanced human prostate tumor growth and angiogenesis and upregulates insulin-like growth factor binding protein-3. International Journal of Cancer. 108: 733-40. PMID 14696100 DOI: 10.1002/Ijc.11620 |
0.338 |
|
| 2004 |
Tyagi AK, Agarwal C, Singh RP, Shroyer KR, Glode LM, Agarwal R. Silibinin down-regulates survivin protein and mRNA expression and causes caspases activation and apoptosis in human bladder transitional-cell papilloma RT4 cells. Biochemical and Biophysical Research Communications. 312: 1178-84. PMID 14651997 DOI: 10.1016/J.Bbrc.2003.11.038 |
0.373 |
|
| 2004 |
Agarwal C, Singh RP, Dhanalakshmi S, Agarwal R. Anti-angiogenic efficacy of grape seed extract in endothelial cells. Oncology Reports. 11: 681-685. DOI: 10.3892/Or.11.3.681 |
0.316 |
|
| 2003 |
Agarwal C, Singh RP, Dhanalakshmi S, Tyagi AK, Tecklenburg M, Sclafani RA, Agarwal R. Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. Oncogene. 22: 8271-82. PMID 14614451 DOI: 10.1038/Sj.Onc.1207158 |
0.369 |
|
| 2003 |
Qi L, Singh RP, Lu Y, Agarwal R, Harrison GS, Franzusoff A, Glode LM. Epidermal growth factor receptor mediates silibinin-induced cytotoxicity in a rat glioma cell line. Cancer Biology & Therapy. 2: 526-31. PMID 14614320 DOI: 10.4161/Cbt.2.5.452 |
0.324 |
|
| 2003 |
Dhanalakshmi S, Mallikarjuna GU, Singh RP, Agarwal R. Dual efficacy of silibinin in protecting or enhancing ultraviolet B radiation-caused apoptosis in HaCaT human immortalized keratinocytes. Carcinogenesis. 25: 99-106. PMID 14555614 DOI: 10.1093/Carcin/Bgg188 |
0.376 |
|
| 2003 |
Singh RP, Agarwal R. Tumor angiogenesis: a potential target in cancer control by phytochemicals. Current Cancer Drug Targets. 3: 205-17. PMID 12769689 DOI: 10.2174/1568009033481985 |
0.323 |
|
| 2003 |
Singh RP, Agarwal C, Agarwal R. Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes. Carcinogenesis. 24: 555-63. PMID 12663518 DOI: 10.1093/Carcin/24.3.555 |
0.386 |
|
| 2003 |
Singh RP, Agarwal R. Flavonoid antioxidant silymarin and skin cancer. Antioxidants & Redox Signaling. 4: 655-63. PMID 12230878 DOI: 10.1089/15230860260220166 |
0.349 |
|
| 2003 |
Sharma G, Singh RP, Agarwal R. Growth inhibitory and apoptotic effects of inositol hexaphosphate in transgenic adenocarcinoma of mouse prostate (TRAMP-C1) cells. International Journal of Oncology. 23: 1413-1418. DOI: 10.3892/Ijo.23.5.1413 |
0.382 |
|
| 2002 |
Agarwal C, Singh RP, Agarwal R. Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c release. Carcinogenesis. 23: 1869-76. PMID 12419835 DOI: 10.1093/Carcin/23.11.1869 |
0.353 |
|
| 2002 |
Dhanalakshmi S, Singh RP, Agarwal C, Agarwal R. Silibinin inhibits constitutive and TNFα-induced activation of NF-κB and sensitizes human prostate carcinoma DU145 cells to TNFα-induced apoptosis Oncogene. 21: 1759-1767. PMID 11896607 DOI: 10.1038/Sj.Onc.1205240 |
0.386 |
|
| 2002 |
Singh RP, Tyagi AK, Zhao J, Agarwal R. Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis. Carcinogenesis. 23: 499-510. PMID 11895866 DOI: 10.1093/Carcin/23.3.499 |
0.372 |
|
| 2002 |
Singh RP, Dhanalakshmi S, Agarwal R. Phytochemicals as Cell Cycle Modulators A Less Toxic Approach in Halting Human Cancers Cell Cycle. 1: 155-160. DOI: 10.4161/Cc.1.3.117 |
0.359 |
|
| 2001 |
Zi X, Singh RP, Agarwal R. Impairment of erbB1 receptor and fluid-phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma DU145 cells. Carcinogenesis. 21: 2225-35. PMID 11133812 DOI: 10.1093/Carcin/21.12.2225 |
0.354 |
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