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A. Norrie Pearce - Publications

Affiliations: 
1998-2001 Chemistry The University of Auckland, Auckland, Auckland, New Zealand 
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Pearce AN, Chen D, Edmeades LR, Cadelis MM, Troudi A, Brunel JM, Bourguet-Kondracki ML, Copp BR. Repurposing primaquine as a polyamine conjugate to become an antibiotic adjuvant. Bioorganic & Medicinal Chemistry. 38: 116110. PMID 33831695 DOI: 10.1016/j.bmc.2021.116110  0.547
2019 Pearce AN, Hill CAE, Page MJ, Keyzers RA, Copp BR. An Acetylenic Lipid from the New Zealand Ascidian : Exemplification of an Improved Workflow for Determination of Absolute Configuration of Long-Chain 2-Amino-3-alkanols. Journal of Natural Products. PMID 31356078 DOI: 10.1021/Acs.Jnatprod.9B00504  0.615
2019 Molinski TF, Salib MN, Pearce AN, Copp BR. The Configuration of Distaminolyne A is S: Quantitative Evaluation of Exciton Coupling Circular Dichroism of N, O- Bis-arenoyl-1-amino-2-alkanols. Journal of Natural Products. PMID 30958674 DOI: 10.1021/Acs.Jnatprod.8B00937  0.574
2018 Pearce AN, Copp BR, Molinski TF. Enantiomeric Variability of Distaminolyne A. Refinement of ECD and NMR Methods for Determining Optical Purity of 1-Amino-2-Alkanols. Molecules (Basel, Switzerland). 24. PMID 30591663 DOI: 10.3390/Molecules24010090  0.569
2017 Pearce AN, Kaiser M, Copp BR. Synthesis and antimalarial evaluation of artesunate-polyamine and trioxolane-polyamine conjugates. European Journal of Medicinal Chemistry. 140: 595-603. PMID 28988153 DOI: 10.1016/J.Ejmech.2017.09.040  0.585
2017 Davidson SJ, Pearce AN, Copp BR, Barker D. Total Synthesis of (-)-Bicubebin A, B, (+)-Bicubebin C and Structural Reassignment of (-)-cis-Cubebin. Organic Letters. PMID 28901148 DOI: 10.1021/Acs.Orglett.7B02644  0.582
2015 Wang J, Pearce AN, Chan ST, Taylor RB, Page MJ, Valentin A, Bourguet-Kondracki ML, Dalton JP, Wiles S, Copp BR. Biologically Active Acetylenic Amino Alcohol and N-Hydroxylated 1,2,3,4-Tetrahydro-β-carboline Constituents of the New Zealand Ascidian Pseudodistoma opacum. Journal of Natural Products. PMID 26670413 DOI: 10.1021/Acs.Jnatprod.5B00770  0.769
2013 Lam CF, Pearce AN, Tan SH, Kaiser M, Copp BR. Discovery and evaluation of thiazinoquinones as anti-protozoal agents. Marine Drugs. 11: 3472-99. PMID 24022732 DOI: 10.3390/Md11093472  0.732
2013 Liew LP, Pearce AN, Kaiser M, Copp BR. Synthesis and in vitro and in vivo evaluation of antimalarial polyamines. European Journal of Medicinal Chemistry. 69: 22-31. PMID 23995215 DOI: 10.1016/J.Ejmech.2013.07.055  0.727
2012 Lam CF, Grkovic T, Pearce AN, Copp BR. Investigation of the electrophilic reactivity of the cytotoxic marine alkaloid discorhabdin B. Organic & Biomolecular Chemistry. 10: 3092-7. PMID 22395232 DOI: 10.1039/C2Ob07090A  0.764
2011 Chan ST, Pearce AN, Januario AH, Page MJ, Kaiser M, McLaughlin RJ, Harper JL, Webb VL, Barker D, Copp BR. Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum. The Journal of Organic Chemistry. 76: 9151-6. PMID 21958335 DOI: 10.1021/Jo201654H  0.747
2011 Chan ST, Pearce AN, Page MJ, Kaiser M, Copp BR. Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum. Journal of Natural Products. 74: 1972-9. PMID 21846091 DOI: 10.1021/Np200509G  0.749
2011 Finlayson R, Pearce AN, Page MJ, Kaiser M, Bourguet-Kondracki ML, Harper JL, Webb VL, Copp BR. Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian Didemnum sp. Journal of Natural Products. 74: 888-92. PMID 21348447 DOI: 10.1021/Np1008619  0.621
2010 Grkovic T, Pearce AN, Munro MH, Blunt JW, Davies-Coleman MT, Copp BR. Isolation and characterization of diastereomers of discorhabdins H and K and assignment of absolute configuration to discorhabdins D, N, Q, S, T, and U. Journal of Natural Products. 73: 1686-93. PMID 20860391 DOI: 10.1021/Np100443C  0.749
2010 Appleton DR, Pearce AN, Copp BR. anti-Tuberculosis natural products: synthesis and biological evaluation of pyridoacridine alkaloids related to ascididemin Tetrahedron. 66: 4977-4986. DOI: 10.1016/J.Tet.2010.05.033  0.726
2010 LINDSAY BS, PEARCE AN, COPP BR. ChemInform Abstract: Efficient and Convenient Pyridine Ring-E Formation of the Cytotoxic Marine Alkaloid Ascididemin and Related Analogues. Cheminform. 28: no-no. DOI: 10.1002/CHIN.199742264  0.746
2008 Chia EW, Pearce AN, Berridge MV, Larsen L, Perry NB, Sansom CE, Godfrey CA, Hanton LR, Lu GL, Walton M, Denny WA, Webb VL, Copp BR, Harper JL. Synthesis and anti-inflammatory structure-activity relationships of thiazine-quinoline-quinones: inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis. Bioorganic & Medicinal Chemistry. 16: 9432-42. PMID 18835721 DOI: 10.1016/J.Bmc.2008.09.052  0.61
2008 Pearce AN, Chia EW, Berridge MV, Maas EW, Page MJ, Harper JL, Webb VL, Copp BR. Orthidines A-E, tubastrine, 3,4-dimethoxyphenethyl-β-guanidine, and 1,14-sperminedihomovanillamide: potential anti-inflammatory alkaloids isolated from the New Zealand ascidian Aplidium orthium that act as inhibitors of neutrophil respiratory burst Tetrahedron. 64: 5748-5755. DOI: 10.1016/J.Tet.2008.04.012  0.647
2008 Pearce AN, Chia EW, Berridge MV, Maas EW, Page MJ, Harper JL, Webb VL, Copp BR. ChemInform Abstract: Orthidines A-E, Tubastrine, 3,4-Dimethoxyphenethyl-β-guanidine, and 1,14-Sperminedihomovanillamide: Potential Antiinflammatory Alkaloids Isolated from the New Zealand Ascidian Aplidium orthium that Act as Inhibitors of Neutrophil Respiratory Burst. Cheminform. 39. DOI: 10.1002/CHIN.200845184  0.545
2007 Pearce AN, Chia EW, Berridge MV, Clark GR, Harper JL, Larsen L, Maas EW, Page MJ, Perry NB, Webb VL, Copp BR. Anti-inflammatory thiazine alkaloids isolated from the New Zealand ascidian Aplidium sp.: inhibitors of the neutrophil respiratory burst in a model of gouty arthritis. Journal of Natural Products. 70: 936-40. PMID 17497807 DOI: 10.1021/Np060626O  0.634
2007 Copp BR, Pearce AN. Natural product growth inhibitors of Mycobacterium tuberculosis. Natural Product Reports. 24: 278-97. PMID 17389998 DOI: 10.1039/B513520F  0.611
2007 Pearce AN, Chia EW, Berridge MV, Maas EW, Page MJ, Webb VL, Harper JL, Copp BR. E/Z-rubrolide O, an anti-inflammatory halogenated furanone from the New Zealand ascidian Synoicum n. sp. Journal of Natural Products. 70: 111-3. PMID 17253860 DOI: 10.1021/Np060188L  0.601
2003 Pearce A, Appleton DR, Babcock RC, Copp BR. Distomadines A and B, novel 6-hydroxyquinoline alkaloids from the New Zealand ascidian, Pseudodistoma aureum Tetrahedron Letters. 44: 3897-3899. DOI: 10.1016/S0040-4039(03)00831-1  0.748
2002 Appleton DR, Pearce A, Lambert G, Babcock RC, Copp BR. Isodiplamine, cystodytin K and lissoclinidine: novel bioactive alkaloids from the New Zealand ascidian Lissoclinum notti Tetrahedron. 58: 9779-9783. DOI: 10.1016/S0040-4020(02)01296-6  0.754
2001 Pearce AN, Babcock RC, Lambert G, Copp BR. N2,N2,7-trimethylguanine, a new trimethylated guanine natural product from the New Zealand ascidian, Lissoclinum notti. Natural Product Letters. 15: 237-41. PMID 11833618 DOI: 10.1080/10575630108041287  0.555
2001 Pearce AN, Babcock RC, Battershill CN, Lambert G, Copp BR. Enantiomeric 1,2,3-trithiane-containing alkaloids and two new 1,3-dithiane alkaloids from New Zealand ascidians. The Journal of Organic Chemistry. 66: 8257-9. PMID 11722237 DOI: 10.1021/Jo010769+  0.562
1997 Lindsay BS, Pearce AN, Copp BR. Efficient and Convenient Pyridine Ring-E Formation of the Cytotoxic Marine Alkaloid Ascididemin and Related Analogues. Synthetic Communications. 27: 2587-2592. DOI: 10.1080/00397919708004128  0.754
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