Guiquan Chen - Publications

Affiliations: 
Nanjing University, Nanjing Shi, Jiangsu Sheng, China 
Area:
Neurodegenerative diseases

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Shi T, Shen S, Shi Y, Wang Q, Zhang G, Lin J, Chen J, Bai F, Zhang L, Wang Y, Gong W, Shao X, Chen G, Yan W, Chen X, et al. Osteocyte-derived sclerostin impairs cognitive function during ageing and Alzheimer's disease progression. Nature Metabolism. PMID 38409606 DOI: 10.1038/s42255-024-00989-x  0.311
2022 Xia Y, Zhang Y, Xu M, Zou X, Gao J, Ji MH, Chen G. Presenilin enhancer2 is critical for the transition of apical progenitors to neurons but not basal progenitors in the developing hippocampus. Development (Cambridge, England). PMID 35575074 DOI: 10.1242/dev.200272  0.324
2022 Li QQ, Chen J, Hu P, Jia M, Sun JH, Feng HY, Qiao FC, Zang YY, Shi YY, Chen G, Sheng N, Xu Y, Yang JJ, Xu Z, Shi YS. Enhancing GluN2A-type NMDA receptors impairs long-term synaptic plasticity and learning and memory. Molecular Psychiatry. PMID 35484243 DOI: 10.1038/s41380-022-01579-7  0.314
2021 Zhang T, Ding H, Wang Y, Yuan Z, Zhang Y, Chen G, Xu Y, Chen L. Akt3-mTOR regulates hippocampal neurogenesis in adult mouse. Journal of Neurochemistry. PMID 34077553 DOI: 10.1111/jnc.15441  0.374
2017 Xu C, Yu L, Hou J, Jackson RJ, Wang H, Huang C, Liu T, Wang Q, Zou X, Morris RG, Spires-Jones TL, Yang Z, Yin Z, Xu Y, Chen G. Conditional Deletion of PDK1 in the Forebrain Causes Neuron Loss and Increased Apoptosis during Cortical Development. Frontiers in Cellular Neuroscience. 11: 330. PMID 29104535 DOI: 10.3389/Fncel.2017.00330  0.459
2016 Wang H, Zhang BF, Zhang TT, Wang L, Zou XY, Xu Y, Chen L, Chen GQ. Impaired Spatial Learning is Associated with Disrupted Integrity of the White Matter in Akt3 Knockout Mice. Cns Neuroscience & Therapeutics. PMID 27671373 DOI: 10.1111/cns.12647  0.392
2015 Holland PR, Searcy JL, Salvadores N, Scullion G, Chen G, Lawson G, Scott F, Bastin ME, Ihara M, Kalaria R, Wood ER, Smith C, Wardlaw JM, Horsburgh K. Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 1005-14. PMID 25669904 DOI: 10.1038/Jcbfm.2015.12  0.366
2011 Horsburgh K, Reimer MM, Holland P, Chen G, Scullion G, Fowler JH. Axon-glial disruption: the link between vascular disease and Alzheimer's disease? Biochemical Society Transactions. 39: 881-5. PMID 21787317 DOI: 10.1042/Bst0390881  0.347
2011 Hoffmann L, Scullion G, Chen G, Holland P, McCulloch J, Horsburgh K. P4-039: Temporal influence of CAA on cerebrovascular and white matter integrity in parallel with cognition in Tg-SwDI mice Alzheimer's & Dementia. 7: S711-S711. DOI: 10.1016/J.Jalz.2011.05.2059  0.393
2010 Chen G, Zou X, Watanabe H, van Deursen JM, Shen J. CREB binding protein is required for both short-term and long-term memory formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13066-77. PMID 20881124 DOI: 10.1523/Jneurosci.2378-10.2010  0.314
2009 Chen PE, Errington ML, Kneussel M, Chen G, Annala AJ, Rudhard YH, Rast GF, Specht CG, Tigaret CM, Nassar MA, Morris RG, Bliss TV, Schoepfer R. Behavioral deficits and subregion-specific suppression of LTP in mice expressing a population of mutant NMDA receptors throughout the hippocampus. Learning & Memory (Cold Spring Harbor, N.Y.). 16: 635-44. PMID 19794189 DOI: 10.1101/Lm.1316909  0.475
2009 Peng Y, Xing C, Xu S, Lemere CA, Chen G, Liu B, Wang L, Feng Y, Wang X. L-3-n-butylphthalide improves cognitive impairment induced by intracerebroventricular infusion of amyloid-beta peptide in rats. European Journal of Pharmacology. 621: 38-45. PMID 19737553 DOI: 10.1016/j.ejphar.2009.08.036  0.319
2009 Tabuchi K, Chen G, Südhof TC, Shen J. Conditional forebrain inactivation of nicastrin causes progressive memory impairment and age-related neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7290-301. PMID 19494151 DOI: 10.1523/Jneurosci.1320-09.2009  0.362
2008 Frenkel D, Puckett L, Petrovic S, Xia W, Chen G, Vega J, Dembinsky-Vaknin A, Shen J, Plante M, Burt DS, Weiner HL. A nasal proteosome adjuvant activates microglia and prevents amyloid deposition. Annals of Neurology. 63: 591-601. PMID 18360829 DOI: 10.1002/Ana.21340  0.443
2008 Peng Y, Xing C, Lemere CA, Chen G, Wang L, Feng Y, Wang X. l-3-n-Butylphthalide ameliorates beta-amyloid-induced neuronal toxicity in cultured neuronal cells. Neuroscience Letters. 434: 224-9. PMID 18328624 DOI: 10.1016/j.neulet.2008.01.080  0.312
2007 Chen G, Chen KS, Kobayashi D, Barbour R, Motter R, Games D, Martin SJ, Morris RG. Active beta-amyloid immunization restores spatial learning in PDAPP mice displaying very low levels of beta-amyloid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2654-62. PMID 17344403 DOI: 10.1523/Jneurosci.3710-06.2007  0.512
2005 Saura CA, Chen G, Malkani S, Choi SY, Takahashi RH, Zhang D, Gouras GK, Kirkwood A, Morris RG, Shen J. Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6755-64. PMID 16033885 DOI: 10.1523/Jneurosci.1247-05.2005  0.639
2004 Saura CA, Chen G, Malkani S, Choi S, Kirkwood A, Morris RG, Shen J. P4-260 Inactivation of PS1/G-secretase in APP transgenic mice rescues associative and working memory but not reference memory deficits Neurobiology of Aging. 25: S549. DOI: 10.1016/S0197-4580(04)81818-9  0.5
2000 Chen G, Chen KS, Knox J, Inglis J, Bernard A, Martin SJ, Justice A, McConlogue L, Games D, Freedman SB, Morris RG. A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease. Nature. 408: 975-9. PMID 11140684 DOI: 10.1038/35050103  0.625
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