Simon J. Powis - Publications

Affiliations: 
Saint Andrews University, Saint Andrews, Scotland, United Kingdom 
Website:
http://medicine.st-andrews.ac.uk/contacts/staffProfile.aspx?sunID=sjp10

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Lenart I, Truong LH, Nguyen DD, Rasiukienė O, Tsao E, Armstrong J, Kumar P, McHugh K, Pereira BI, Maan BS, Garstka MA, Bowness P, Blake N, Powis SJ, Gould K, et al. Intrinsic Folding Properties of the HLA-B27 Heavy Chain Revealed by Single Chain Trimer Versions of Peptide-Loaded Class I Major Histocompatibility Complex Molecules. Frontiers in Immunology. 13: 902135. PMID 35958592 DOI: 10.3389/fimmu.2022.902135  0.415
2022 Kumar P, Boyne C, Brown S, Qureshi A, Thorpe P, Synowsky SA, Shirran S, Powis SJ. Tumour-associated antigenic peptides are present in the HLA class I ligandome of cancer cell line derived extracellular vesicles. Immunology. PMID 35318648 DOI: 10.1111/imm.13471  0.334
2021 Boyne C, Lennox D, Beech O, Powis SJ, Kumar P. What Is the Role of HLA-I on Cancer Derived Extracellular Vesicles? Defining the Challenges in Characterisation and Potential Uses of This Ligandome. International Journal of Molecular Sciences. 22. PMID 34948350 DOI: 10.3390/ijms222413554  0.316
2019 Powis SJ, Antoniou AN. Measuring Synthesis and Degradation of MHC Class I Molecules. Methods in Molecular Biology (Clifton, N.J.). 1988: 83-100. PMID 31147934 DOI: 10.1007/978-1-4939-9450-2_7  0.406
2019 Arya S, Wiatrek-Moumoulidis D, Synowsky SA, Shirran SL, Botting CH, Powis SJ, Stewart AJ. Quantitative proteomic changes in LPS-activated monocyte-derived dendritic cells: A SWATH-MS study. Scientific Reports. 9: 4343. PMID 30867486 DOI: 10.1038/S41598-019-40773-6  0.332
2018 Antoniou AN, Lenart I, Kriston-Vizi J, Iwawaki T, Turmaine M, McHugh K, Ali S, Blake N, Bowness P, Bajaj-Elliott M, Gould K, Nesbeth D, Powis SJ. exploits HLA-B27 and host unfolded protein responses to promote intracellular replication. Annals of the Rheumatic Diseases. PMID 30355574 DOI: 10.1136/Annrheumdis-2018-213532  0.417
2017 Synowsky SA, Shirran SL, Cooke FGM, Antoniou AN, Botting CH, Powis SJ. The major histocompatibility complex class I immunopeptidome of extracellular vesicles. The Journal of Biological Chemistry. PMID 28860189 DOI: 10.1074/Jbc.M117.805895  0.499
2017 McReynolds N, Cooke FG, Chen M, Powis SJ, Dholakia K. Multimodal discrimination of immune cells using a combination of Raman spectroscopy and digital holographic microscopy. Scientific Reports. 7: 43631. PMID 28256551 DOI: 10.1038/Srep43631  0.329
2017 Schubert M, Volckaert K, Karl M, Morton A, Liehm P, Miles GB, Powis SJ, Gather MC. Lasing in Live Mitotic and Non-Phagocytic Cells by Efficient Delivery of Microresonators. Scientific Reports. 7: 40877. PMID 28102341 DOI: 10.1038/Srep40877  0.303
2017 McReynolds N, Cooke FGM, Chen M, Powis SJ, Dholakia K. Combining Raman spectroscopy and digital holographic microscopy for label-free classification of human immune cells (Conference Presentation) Proceedings of Spie. 10057. DOI: 10.1117/12.2250505  0.315
2016 Guiliano DB, North H, Panayoitou E, Campbell EC, McHugh K, Cooke FG, Silvestre M, Bowness P, Powis SJ, Antoniou AN. Polymorphisms in the F pocket of HLA-B27 subtypes strongly impact on assembly, chaperone interactions and heavy chain misfolding. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27723268 DOI: 10.1002/Art.39948  0.437
2016 Powis SJ, Colbert RA. HLA-B27: The Story Continues to Unfold. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26749536 DOI: 10.1002/Art.39566  0.356
2015 Chen M, McReynolds N, Campbell EC, Mazilu M, Barbosa J, Dholakia K, Powis SJ. The use of wavelength modulated Raman spectroscopy in label-free identification of T lymphocyte subsets, natural killer cells and dendritic cells. Plos One. 10: e0125158. PMID 25992777 DOI: 10.1371/Journal.Pone.0125158  0.314
2014 Guiliano DB, Fussell H, Lenart I, Tsao E, Nesbeth D, Fletcher AJ, Campbell EC, Yousaf N, Williams S, Santos S, Cameron A, Towers GJ, Kellam P, Hebert DN, Gould KG, ... Powis SJ, et al. Endoplasmic reticulum degradation-enhancing α-mannosidase-like protein 1 targets misfolded HLA-B27 dimers for endoplasmic reticulum-associated degradation. Arthritis & Rheumatology (Hoboken, N.J.). 66: 2976-88. PMID 25132672 DOI: 10.1002/Art.38809  0.367
2014 Riches A, Campbell E, Borger E, Powis S. Regulation of exosome release from mammary epithelial and breast cancer cells - a new regulatory pathway. European Journal of Cancer (Oxford, England : 1990). 50: 1025-34. PMID 24462375 DOI: 10.1016/J.Ejca.2013.12.019  0.304
2012 Campbell EC, Antoniou AN, Powis SJ. The multi-faceted nature of HLA class I dimer molecules. Immunology. 136: 380-4. PMID 22533699 DOI: 10.1111/J.1365-2567.2012.03593.X  0.487
2012 Makhadiyeva D, Lam L, Moatari M, Vallance J, Zheng Y, Campbell EC, Powis SJ. MHC class I dimer formation by alteration of the cellular redox environment and induction of apoptosis. Immunology. 135: 133-9. PMID 22044191 DOI: 10.1111/J.1365-2567.2011.03518.X  0.484
2012 Lenart I, Guiliano DB, Burn G, Campbell EC, Morley KD, Fussell H, Powis SJ, Antoniou AN. The MHC Class I heavy chain structurally conserved cysteines 101 and 164 participate in HLA-B27 dimer formation. Antioxidants & Redox Signaling. 16: 33-43. PMID 21902594 DOI: 10.1089/Ars.2010.3693  0.386
2012 Antoniou AN, Lenart I, Guiliano DB, Powis SJ. Antigen Processing and Presentation by MHC Class I, II, and Nonclassical Molecules Vaccinology: Principles and Practice. 29-46. DOI: 10.1002/9781118345313.ch3  0.327
2011 Antoniou AN, Guiliano DB, Lenart I, Burn G, Powis SJ. The oxidative folding and misfolding of human leukocyte antigen-b27. Antioxidants & Redox Signaling. 15: 669-84. PMID 21671754 DOI: 10.1089/Ars.2010.3692  0.44
2011 Campbell EC, Fettke F, Bhat S, Morley KD, Powis SJ. Expression of MHC class I dimers and ERAP1 in an ankylosing spondylitis patient cohort. Immunology. 133: 379-85. PMID 21574996 DOI: 10.1111/J.1365-2567.2011.03453.X  0.382
2010 Liu C, Fu H, Flutter B, Powis SJ, Gao B. Suppression of MHC class I surface expression by calreticulin's P-domain in a calreticulin deficient cell line. Biochimica Et Biophysica Acta. 1803: 544-52. PMID 20226820 DOI: 10.1016/J.Bbamcr.2010.03.001  0.456
2009 Powis SJ, Santos SG, Antoniou AN. Biochemical features of HLA-B27 and antigen processing. Advances in Experimental Medicine and Biology. 649: 210-6. PMID 19731631 DOI: 10.1007/978-1-4419-0298-6_15  0.479
2009 Lynch S, Santos SG, Campbell EC, Nimmo AM, Botting C, Prescott A, Antoniou AN, Powis SJ. Novel MHC class I structures on exosomes. Journal of Immunology (Baltimore, Md. : 1950). 183: 1884-91. PMID 19596992 DOI: 10.4049/Jimmunol.0900798  0.482
2009 Powis SJ, Nesbeth D, Lenart I, Fussell H, Lamb T, Gould K, Antoniou AN. Rapid acidification and alkylation: redox analysis of the MHC class I pathway. Journal of Immunological Methods. 340: 81-5. PMID 18838077 DOI: 10.1016/J.Jim.2008.09.006  0.472
2009 Fussell H, Lenart I, Nesbeth D, Guiliano D, Gould K, Powis S, Antoniou AN. HLA-B27 misfolding and dimerisation Comparative Biochemistry and Physiology a-Molecular & Integrative Physiology. 153. DOI: 10.1016/J.Cbpa.2009.04.327  0.359
2009 Powis S. Inflammatory arthritis and HLA-B27: Is there a role for protein misfolding? Comparative Biochemistry and Physiology a-Molecular & Integrative Physiology. 153. DOI: 10.1016/J.Cbpa.2009.04.326  0.336
2008 Fussell H, Nesbeth D, Lenart I, Campbell EC, Lynch S, Santos S, Gould K, Powis SJ, Antoniou AN. Novel detection of in vivo HLA-B27 conformations correlates with ankylosing spondylitis association. Arthritis and Rheumatism. 58: 3419-24. PMID 18975339 DOI: 10.1002/Art.23990  0.393
2008 Santos SG, Lynch S, Campbell EC, Antoniou AN, Powis SJ. Induction of HLA-B27 heavy chain homodimer formation after activation in dendritic cells. Arthritis Research & Therapy. 10: R100. PMID 18759962 DOI: 10.1186/Ar2492  0.463
2008 Antoniou AN, Powis SJ. Pathogen evasion strategies for the major histocompatibility complex class I assembly pathway. Immunology. 124: 1-12. PMID 18284468 DOI: 10.1111/J.1365-2567.2008.02804.X  0.477
2007 Antoniou AN, Santos SG, Campbell EC, Lynch S, Arosa FA, Powis SJ. ERp57 interacts with conserved cysteine residues in the MHC class I peptide-binding groove. Febs Letters. 581: 1988-92. PMID 17467700 DOI: 10.1016/J.Febslet.2007.04.034  0.461
2007 Santos SG, Campbell EC, Lynch S, Wong V, Antoniou AN, Powis SJ. Major histocompatibility complex class I-ERp57-tapasin interactions within the peptide-loading complex. The Journal of Biological Chemistry. 282: 17587-93. PMID 17459881 DOI: 10.1074/Jbc.M702212200  0.443
2007 Arosa FA, Santos SG, Powis SJ. Open conformers: the hidden face of MHC-I molecules. Trends in Immunology. 28: 115-23. PMID 17261379 DOI: 10.1016/J.It.2007.01.002  0.431
2006 Powis SJ. CLIP-region mediated interaction of Invariant chain with MHC class I molecules. Febs Letters. 580: 3112-6. PMID 16678175 DOI: 10.1016/J.Febslet.2006.04.060  0.467
2006 Santos SG, Antoniou AN, Sampaio P, Powis SJ, Arosa FA. Lack of tyrosine 320 impairs spontaneous endocytosis and enhances release of HLA-B27 molecules. Journal of Immunology (Baltimore, Md. : 1950). 176: 2942-9. PMID 16493052 DOI: 10.4049/Jimmunol.176.5.2942  0.467
2005 Tourdot S, Nejmeddine M, Powis SJ, Gould KG. Different MHC class I heavy chains compete with each other for folding independently of beta 2-microglobulin and peptide. Journal of Immunology (Baltimore, Md. : 1950). 174: 925-33. PMID 15634915 DOI: 10.4049/Jimmunol.174.2.925  0.457
2004 Santos SG, Powis SJ, Arosa FA. Misfolding of major histocompatibility complex class I molecules in activated T cells allows cis-interactions with receptors and signaling molecules and is associated with tyrosine phosphorylation. The Journal of Biological Chemistry. 279: 53062-70. PMID 15471856 DOI: 10.1074/Jbc.M408794200  0.409
2004 Ford S, Antoniou A, Butcher GW, Powis SJ. Competition for access to the rat major histocompatibility complex class I peptide-loading complex reveals optimization of peptide cargo in the absence of transporter associated with antigen processing (TAP) association. The Journal of Biological Chemistry. 279: 16077-82. PMID 14764587 DOI: 10.1074/Jbc.M400456200  0.448
2004 Antoniou AN, Ford S, Taurog JD, Butcher GW, Powis SJ. Formation of HLA-B27 homodimers and their relationship to assembly kinetics. The Journal of Biological Chemistry. 279: 8895-902. PMID 14684742 DOI: 10.1074/Jbc.M311757200  0.494
2003 Ohta Y, Powis SJ, Lohr RL, Nonaka M, Pasquier LD, Flajnik MF. Two highly divergent ancient allelic lineages of the transporter associated with antigen processing (TAP) gene in Xenopus: further evidence for co-evolution among MHC class I region genes. European Journal of Immunology. 33: 3017-27. PMID 14579270 DOI: 10.1002/Eji.200324207  0.38
2003 Antoniou AN, Powis SJ. Characterization of the ERp57-Tapasin complex by rapid cellular acidification and thiol modification. Antioxidants & Redox Signaling. 5: 375-9. PMID 13678524 DOI: 10.1089/152308603768295104  0.434
2003 González-Muñoz AL, Le Rolle AF, Brun H, Hedrich HJ, Wedekind D, Powis SJ, Joly E, Butcher GW. A novel instance of class I modification (cim) affecting two of three rat class I RT1-A molecules within one MHC haplotype. Journal of Immunology (Baltimore, Md. : 1950). 171: 274-84. PMID 12817008 DOI: 10.4049/Jimmunol.171.1.274  0.443
2003 Antoniou AN, Powis SJ, Elliott T. Assembly and export of MHC class I peptide ligands. Current Opinion in Immunology. 15: 75-81. PMID 12495737 DOI: 10.1016/S0952-7915(02)00010-9  0.473
2002 Antoniou AN, Ford S, Pilley ES, Blake N, Powis SJ. Interactions formed by individually expressed TAP1 and TAP2 polypeptide subunits. Immunology. 106: 182-9. PMID 12047747 DOI: 10.1046/J.1365-2567.2002.01415.X  0.496
2002 Antoniou AN, Ford S, Alphey M, Osborne A, Elliott T, Powis SJ. The oxidoreductase ERp57 efficiently reduces partially folded in preference to fully folded MHC class I molecules. The Embo Journal. 21: 2655-63. PMID 12032078 DOI: 10.1093/Emboj/21.11.2655  0.64
2001 Velarde G, Ford RC, Rosenberg MF, Powis SJ. Three-dimensional structure of transporter associated with antigen processing (TAP) obtained by single Particle image analysis. The Journal of Biological Chemistry. 276: 46054-63. PMID 11595746 DOI: 10.1074/Jbc.M108435200  0.343
2001 Deverson EV, Powis SJ, Morrice NA, Herberg JA, Trowsdale J, Butcher GW. Rat tapasin: cDNA cloning and identification as a component of the class I MHC assembly complex. Genes and Immunity. 2: 48-51. PMID 11294569 DOI: 10.1038/Sj.Gene.6363727  0.367
2000 King A, Allan DS, Bowen M, Powis SJ, Joseph S, Verma S, Hiby SE, McMichael AJ, Loke YW, Braud VM. HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells. European Journal of Immunology. 30: 1623-31. PMID 10898498 DOI: 10.1002/1521-4141(200006)30:6<1623::Aid-Immu1623>3.0.Co;2-M  0.409
1999 Newitt S, Powis SJ. Interactions formed by truncated transporter associated with antigen-processing polypeptides. Transplantation Proceedings. 31: 1519-21. PMID 10330988 DOI: 10.1016/S0041-1345(99)00024-X  0.302
1999 Leong LY, Le Rolle AF, Deverson EV, Powis SJ, Larkins AP, Vaage JT, Stokland A, Lambracht-Washington D, Rolstad B, Joly E, Butcher GW. RT1-U: identification of a novel, active, class Ib alloantigen of the rat MHC. Journal of Immunology (Baltimore, Md. : 1950). 162: 743-52. PMID 9916694  0.355
1999 Ohta Y, Powis SJ, Coadwell WJ, Haliniewski DE, Liu Y, Li H, Flajnik MF. Identification and genetic mapping of Xenopus TAP2 genes. Immunogenetics. 49: 171-82. PMID 9914331 DOI: 10.1007/S002510050478  0.417
1998 Morrice NA, Powis SJ. A role for the thiol-dependent reductase ERp57 in the assembly of MHC class I molecules. Current Biology : Cb. 8: 713-6. PMID 9637924 DOI: 10.1016/S0960-9822(98)70279-9  0.496
1997 Powis SJ. Major histocompatibility complex class I molecules interact with both subunits of the transporter associated with antigen processing, TAP1 and TAP2. European Journal of Immunology. 27: 2744-7. PMID 9368636 DOI: 10.1002/Eji.1830271040  0.498
1996 Powis SJ, Young LL, Joly E, Barker PJ, Richardson L, Brandt RP, Melief CJ, Howard JC, Butcher GW. The rat cim effect: TAP allele-dependent changes in a class I MHC anchor motif and evidence against C-terminal trimming of peptides in the ER. Immunity. 4: 159-65. PMID 8624806 DOI: 10.1016/S1074-7613(00)80680-9  0.38
1995 Thorpe CJ, Moss DS, Powis SJ, Howard JC, Butcher GW, Travers PJ. An analysis of the antigen binding site of RT1.Aa suggests an allele-specific motif. Immunogenetics. 41: 329-31. PMID 7721357 DOI: 10.1007/Bf00172160  0.462
1995 Sibille C, Gould KG, Willard-Gallo K, Thomson S, Rivett AJ, Powis S, Butcher GW, De Baetselier P. LMP2+ proteasomes are required for the presentation of specific antigens to cytotoxic T lymphocytes. Current Biology : Cb. 5: 923-30. PMID 7583150 DOI: 10.1016/S0960-9822(95)00182-5  0.47
1993 Franksson L, George E, Powis S, Butcher G, Howard J, Kärre K. Tumorigenicity conferred to lymphoma mutant by major histocompatibility complex-encoded transporter gene. The Journal of Experimental Medicine. 177: 201-5. PMID 8418201 DOI: 10.1084/Jem.177.1.201  0.493
1993 McCulloch J, Williamson SA, Powis SJ, Edington N. The effect of EHV-1 infection upon circulating leucocyte populations in the natural equine host. Veterinary Microbiology. 37: 147-61. PMID 8296444 DOI: 10.1016/0378-1135(93)90189-E  0.312
1992 Powis SJ, Deverson EV, Coadwell WJ, Ciruela A, Huskisson NS, Smith H, Butcher GW, Howard JC. Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule. Nature. 357: 211-5. PMID 1350326 DOI: 10.1038/357211a0  0.36
1992 Momburg F, Ortiz-Navarrete V, Neefjes J, Goulmy E, van de Wal Y, Spits H, Powis SJ, Butcher GW, Howard JC, Walden P. Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation. Nature. 360: 174-7. PMID 1299222 DOI: 10.1038/360174A0  0.477
1991 Powis SJ, Howard JC, Butcher GW. The major histocompatibility complex class II-linked cim locus controls the kinetics of intracellular transport of a classical class I molecule. The Journal of Experimental Medicine. 173: 913-21. PMID 2007857 DOI: 10.1084/Jem.173.4.913  0.445
1991 Livingstone AM, Powis SJ, Günther E, Cramer DV, Howard JC, Butcher GW. Cim: an MHC class II-linked allelism affecting the antigenicity of a classical class I molecule for T lymphocytes. Immunogenetics. 34: 157-63. PMID 1909994 DOI: 10.1007/Bf00205818  0.451
1991 Powis SJ, Townsend AR, Deverson EV, Bastin J, Butcher GW, Howard JC. Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter. Nature. 354: 528-31. PMID 1758495 DOI: 10.1038/354528A0  0.468
1990 Rada C, Lorenzi R, Powis SJ, van den Bogaerde J, Parham P, Howard JC. Concerted evolution of class I genes in the major histocompatibility complex of murine rodents. Proceedings of the National Academy of Sciences of the United States of America. 87: 2167-71. PMID 2315309 DOI: 10.1073/Pnas.87.6.2167  0.365
1989 Livingstone AM, Powis SJ, Diamond AG, Butcher GW, Howard JC. A trans-acting major histocompatibility complex-linked gene whose alleles determine gain and loss changes in the antigenic structure of a classical class I molecule. The Journal of Experimental Medicine. 170: 777-95. PMID 2475574 DOI: 10.1084/Jem.170.3.777  0.432
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