| Year |
Citation |
Score |
| 2023 |
Farahat AA, Kumar A, Wenzler T, Brun R, Paul A, Guo P, Wilson WD, Boykin DW. Investigation of the effect of structure modification of furamidine on the DNA minor groove binding and antiprotozoal activity. European Journal of Medicinal Chemistry. 252: 115287. PMID 36958267 DOI: 10.1016/j.ejmech.2023.115287 |
0.355 |
|
| 2022 |
Yu B, Roy Choudhury M, Yang X, Benoit SL, Womack E, Van Mouwerik Lyles K, Acharya A, Kumar A, Yang C, Pavlova A, Zhu M, Yuan Z, Gumbart JC, Boykin DW, Maier RJ, et al. Restoring and Enhancing the Potency of Existing Antibiotics against Drug-Resistant Gram-Negative Bacteria through the Development of Potent Small-Molecule Adjuvants. Acs Infectious Diseases. PMID 35801980 DOI: 10.1021/acsinfecdis.2c00121 |
0.404 |
|
| 2022 |
Ogbonna EN, Paul A, Ross Terrell J, Fang Z, Chen C, Poon GMK, Boykin DW, Wilson WD. Drug design and DNA structural research inspired by the Neidle laboratory: DNA minor groove binding and transcription factor inhibition by thiophene diamidines. Bioorganic & Medicinal Chemistry. 68: 116861. PMID 35661929 DOI: 10.1016/j.bmc.2022.116861 |
0.318 |
|
| 2021 |
Arafa RK, Ismail MA, Wenzler T, Brun R, Paul A, Wilson WD, Alakhdar AA, Boykin DW. New antiparasitic flexible triaryl diamidines, their prodrugs and aza analogues: Synthesis, in vitro and in vivo biological evaluation, and molecular modelling studies. European Journal of Medicinal Chemistry. 222: 113625. PMID 34146914 DOI: 10.1016/j.ejmech.2021.113625 |
0.657 |
|
| 2020 |
Ha VLT, Erlitzki N, Farahat AA, Kumar A, Boykin DW, Poon GMK. Dissecting Dynamic and Hydration Contributions to Sequence-Dependent DNA Minor Groove Recognition. Biophysical Journal. PMID 32898478 DOI: 10.1016/J.Bpj.2020.08.013 |
0.377 |
|
| 2020 |
Guo P, Farahat AA, Paul A, Kumar A, Boykin DW, Wilson WD. Extending the σ-Hole Motif for Sequence Specific Recognition of the DNA Minor Groove. Biochemistry. PMID 32293884 DOI: 10.1021/Acs.Biochem.0C00090 |
0.422 |
|
| 2019 |
Farahat AA, Guo P, Shoeib H, Paul A, Boykin D, Wilson WD. Small Size Sequence-sensitive Compounds for Specific Recognition of G·C Base Pair in DNA Minor Groove. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31884714 DOI: 10.1002/Chem.201904396 |
0.449 |
|
| 2019 |
Paul A, Guo P, Boykin DW, Wilson WD. A New Generation of Minor-Groove-Binding-Heterocyclic Diamidines That Recognize G·C Base Pairs in an AT Sequence Context. Molecules (Basel, Switzerland). 24. PMID 30866557 DOI: 10.3390/Molecules24050946 |
0.407 |
|
| 2019 |
Depauw S, Lambert M, Jambon S, Paul A, Peixoto P, Nhili R, Marongiu L, Figeac M, Dassi C, Paul-Constant C, Billoré B, Kumar A, Farahat AA, Ismail MA, Mineva E, ... ... Boykin DW, et al. Heterocyclic Diamidine DNA ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation and Cellular Consequences in HOXA9-Dependant Leukemia Cell Model. Journal of Medicinal Chemistry. PMID 30645099 DOI: 10.1021/Acs.Jmedchem.8B01448 |
0.383 |
|
| 2019 |
Mizuta R, Devos JM, Narayanan T, Oliva M, Gray M, Webster J, Ling W, Round A, Munnur D, Mossou E, Farahat A, Boykin DW, Wilson WD, Neidle S, Schweins R, et al. Hierarchical Nanotube Self‐Assembly of DNA Minor Groove‐Binding Ligand DB921 via Alkali Halide Triggering Macromolecular Symposia. 386: 1800243. DOI: 10.1002/Masy.201800243 |
0.322 |
|
| 2018 |
Erlitzki N, Farahat AA, Kumar A, Boykin DW, Poon GMK. DNA recognition by linear indole-biphenyl DNA minor groove ligands. Biophysical Chemistry. 245: 6-16. PMID 30513446 DOI: 10.1016/J.Bpc.2018.11.004 |
0.413 |
|
| 2018 |
Guo P, Farahat AA, Paul A, Harika NK, Boykin DW, Wilson WD. Compound Shape Effects in Minor Groove Binding Affinity and Specificity for Mixed Sequence DNA. Journal of the American Chemical Society. PMID 30353731 DOI: 10.1021/Jacs.8B08152 |
0.441 |
|
| 2018 |
Erlitzki N, Farahat AA, Kumar A, Boykin DW, Poon GM. Structure-Hydration Relationships in DNA Minor Groove Binding Biophysical Journal. 114: 87a. DOI: 10.1016/J.Bpj.2017.11.521 |
0.356 |
|
| 2017 |
Farahat AA, Ismail MA, Kumar A, Wenzler T, Brun R, Paul A, Wilson WD, Boykin DW. Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity. European Journal of Medicinal Chemistry. PMID 29126729 DOI: 10.1016/J.Ejmech.2017.10.056 |
0.396 |
|
| 2017 |
Guo P, Paul A, Kumar A, Harika NK, Wang S, Farahat AA, Boykin DW, Wilson WD. A modular design for minor groove binding and recognition of mixed base pair sequences of DNA. Chemical Communications (Cambridge, England). PMID 28880316 DOI: 10.1039/C7Cc06246J |
0.405 |
|
| 2017 |
da Silva CF, Batista DDGJ, de Araújo JS, Cunha-Junior EF, Stephens CE, Banerjee M, Farahat AA, Akay S, Fisher MK, Boykin DW, Soeiro MNC. Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection. Drug Design, Development and Therapy. 11: 1095-1105. PMID 28435221 DOI: 10.2147/Dddt.S120618 |
0.619 |
|
| 2017 |
Erlitzki N, Huang K, Xhani S, Farahat AA, Kumar A, Boykin DW, Poon GM. Investigation of the electrostatic and hydration properties of DNA minor groove-binding by a heterocyclic diamidine by osmotic pressure. Biophysical Chemistry. PMID 28363467 DOI: 10.1016/J.Bpc.2017.02.008 |
0.371 |
|
| 2017 |
Farahat AA, Kumar A, Say M, Wenzler T, Brun R, Paul A, Wilson WD, Boykin DW. Exploration of DAPI analogues: Synthesis, antitrypanosomal activity, DNA binding and fluorescence properties. European Journal of Medicinal Chemistry. 128: 70-78. PMID 28152428 DOI: 10.1016/J.Ejmech.2017.01.037 |
0.45 |
|
| 2016 |
Paul A, Kumar A, Nanjunda R, Farahat AA, Boykin DW, Wilson WD. Systematic synthetic and biophysical development of mixed sequence DNA binding agents. Organic & Biomolecular Chemistry. PMID 27995240 DOI: 10.1039/C6Ob02390H |
0.408 |
|
| 2016 |
Farahat AA, Bennett-Vaughn C, Mineva EM, Kumar A, Wenzler T, Brun R, Liu Y, Wilson WD, Boykin DW. Synthesis, DNA binding and antitrypanosomal activity of benzimidazole analogues of DAPI. Bioorganic & Medicinal Chemistry Letters. PMID 27843114 DOI: 10.1016/J.Bmcl.2016.11.006 |
0.373 |
|
| 2016 |
Guo P, Paul A, Kumar A, Farahat AA, Kumar D, Wang S, Boykin DW, Wilson WD. The Thiophene "Sigma-Hole" as a Concept for Preorganized, Specific Recognition of G⋅C Base Pairs in the DNA Minor Groove. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27624927 DOI: 10.1002/Chem.201603422 |
0.395 |
|
| 2016 |
Abou-Elkhair RA, Hassan AE, Boykin DW, Wilson WD. Lithium Hexamethyldisilazane Transformation of Transiently Protected 4-Aza/Benzimidazole Nitriles to Amidines and their Dimethyl Sulfoxide Mediated Imidazole Ring Formation. Organic Letters. PMID 27607538 DOI: 10.1021/Acs.Orglett.6B02359 |
0.344 |
|
| 2016 |
Dinkel KD, Stanton JB, Boykin DW, Stephens CE, Madsen-Bouterse SA, Schneider DA. Anti-Prion Activity of DB772 and Related Monothiophene/Furan-Based Analogs in a Persistently Infected Ovine Microglia Culture System. Antimicrobial Agents and Chemotherapy. PMID 27381401 DOI: 10.1128/Aac.00811-16 |
0.345 |
|
| 2016 |
Harika NK, Paul A, Stroeva E, Chai Y, Boykin DW, Germann MW, Wilson WD. Imino proton NMR guides the reprogramming of A•T specific minor groove binders for mixed base pair recognition. Nucleic Acids Research. PMID 27131382 DOI: 10.1093/Nar/Gkw353 |
0.404 |
|
| 2016 |
Stephens DC, Kim HM, Kumar A, Farahat AA, Boykin DW, Poon GM. Pharmacologic efficacy of PU.1 inhibition by heterocyclic dications: a mechanistic analysis. Nucleic Acids Research. PMID 27079976 DOI: 10.1093/Nar/Gkw229 |
0.381 |
|
| 2016 |
Zhu X, Farahat AA, Mattamana M, Joice A, Pandharkar T, Holt E, Banerjee M, Gragg JL, Hu L, Kumar A, Yang S, Wang MZ, Boykin DW, Werbovetz KA. Synthesis and pharmacological evaluation of mono-arylimidamides as antileishmanial agents. Bioorganic & Medicinal Chemistry Letters. PMID 27048943 DOI: 10.1016/J.Bmcl.2016.03.082 |
0.394 |
|
| 2015 |
Berger ML, Maciejewska D, Vanden Eynde JJ, Mottamal M, ?abi?ski J, Ka?mierczak P, Rezler M, Jarak I, Piantanida I, Karminski-Zamola G, Mayence A, Rebernik P, Kumar A, Ismail MA, Boykin DW, et al. Pentamidine analogs as inhibitors of [(3)H]MK-801 and [(3)H]ifenprodil binding to rat brain NMDA receptors. Bioorganic & Medicinal Chemistry. PMID 26117647 DOI: 10.1016/J.Bmc.2015.06.012 |
0.325 |
|
| 2015 |
Paul A, Nanjunda R, Kumar A, Laughlin S, Nhili R, Depauw S, Deuser SS, Chai Y, Chaudhary AS, David-Cordonnier MH, Boykin DW, Wilson WD. Mixed up minor groove binders: Convincing A·T specific compounds to recognize a G·C base pair. Bioorganic & Medicinal Chemistry Letters. PMID 26051649 DOI: 10.1016/J.Bmcl.2015.05.005 |
0.423 |
|
| 2015 |
Laughlin S, Wang S, Kumar A, Farahat AA, Boykin DW, Wilson WD. Resolution of mixed site DNA complexes with dimer-forming minor-groove binders by using electrospray ionization mass spectrometry: compound structure and DNA sequence effects. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 5528-39. PMID 25703690 DOI: 10.1002/Chem.201406322 |
0.404 |
|
| 2015 |
Rice CA, Colon BL, Alp M, Göker H, Boykin DW, Kyle DE. Bis-benzimidazole hits against Naegleria fowleri discovered with new high-throughput screens. Antimicrobial Agents and Chemotherapy. 59: 2037-44. PMID 25605363 DOI: 10.1128/Aac.05122-14 |
0.309 |
|
| 2015 |
Paul A, Chai Y, Boykin DW, Wilson WD. Understanding mixed sequence DNA recognition by novel designed compounds: the kinetic and thermodynamic behavior of azabenzimidazole diamidines. Biochemistry. 54: 577-87. PMID 25495885 DOI: 10.1021/Bi500989R |
0.43 |
|
| 2014 |
Laughlin S, Wang S, Kumar A, Boykin DW, Wilson WD. A novel approach using electrospray ionization mass spectrometry to study competitive binding of small molecules with mixed DNA sequences. Analytical and Bioanalytical Chemistry. 406: 6441-5. PMID 25074546 DOI: 10.1007/S00216-014-8044-9 |
0.415 |
|
| 2014 |
Liu ZY, Wenzler T, Brun R, Zhu X, Boykin DW. Synthesis and antiparasitic activity of new bis-arylimidamides: DB766 analogs modified in the terminal groups. European Journal of Medicinal Chemistry. 83: 167-73. PMID 24956553 DOI: 10.1016/J.Ejmech.2014.06.022 |
0.385 |
|
| 2014 |
Munde M, Kumar A, Peixoto P, Depauw S, Ismail MA, Farahat AA, Paul A, Say MV, David-Cordonnier MH, Boykin DW, Wilson WD. The unusual monomer recognition of guanine-containing mixed sequence DNA by a dithiophene heterocyclic diamidine. Biochemistry. 53: 1218-27. PMID 24495039 DOI: 10.1021/Bi401582T |
0.397 |
|
| 2014 |
Chai Y, Paul A, Rettig M, Wilson WD, Boykin DW. Design and synthesis of heterocyclic cations for specific DNA recognition: from AT-rich to mixed-base-pair DNA sequences. The Journal of Organic Chemistry. 79: 852-66. PMID 24422528 DOI: 10.1021/Jo402599S |
0.432 |
|
| 2014 |
Chai Y, Munde M, Kumar A, Mickelson L, Lin S, Campbell NH, Banerjee M, Akay S, Liu Z, Farahat AA, Nhili R, Depauw S, David-Cordonnier MH, Neidle S, Wilson WD, ... Boykin DW, et al. Structure-dependent binding of arylimidamides to the DNA minor groove. Chembiochem : a European Journal of Chemical Biology. 15: 68-79. PMID 24323836 DOI: 10.1002/Cbic.201300622 |
0.689 |
|
| 2014 |
Ohnmacht SA, Varavipour E, Nanjunda R, Pazitna I, Di Vita G, Gunaratnam M, Kumar A, Ismail MA, Boykin DW, Wilson WD, Neidle S. Discovery of new G-quadruplex binding chemotypes. Chemical Communications (Cambridge, England). 50: 960-3. PMID 24302123 DOI: 10.1039/C3Cc48616H |
0.335 |
|
| 2014 |
Ju W, Yang S, Ansede JH, Stephens CE, Bridges AS, Voyksner RD, Ismail MA, Boykin DW, Tidwell RR, Hall JE, Wang MZ. CYP1A1 and CYP1B1-mediated biotransformation of the antitrypanosomal methamidoxime prodrug DB844 forms novel metabolites through intramolecular rearrangement. Journal of Pharmaceutical Sciences. 103: 337-49. PMID 24186380 DOI: 10.1002/Jps.23765 |
0.327 |
|
| 2014 |
Munde M, Wang S, Kumar A, Stephens CE, Farahat AA, Boykin DW, Wilson WD, Poon GM. Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines. Nucleic Acids Research. 42: 1379-90. PMID 24157839 DOI: 10.1093/Nar/Gkt955 |
0.341 |
|
| 2013 |
Hu L, Patel A, Bondada L, Yang S, Wang MZ, Munde M, Wilson WD, Wenzler T, Brun R, Boykin DW. Synthesis and antiprotozoal activity of dicationic 2,6-diphenylpyrazines and aza-analogues. Bioorganic & Medicinal Chemistry. 21: 6732-41. PMID 24012380 DOI: 10.1016/J.Bmc.2013.08.006 |
0.329 |
|
| 2013 |
Wang S, Kumar A, Aston K, Nguyen B, Bashkin JK, Boykin DW, Wilson WD. Different thermodynamic signatures for DNA minor groove binding with changes in salt concentration and temperature. Chemical Communications (Cambridge, England). 49: 8543-5. PMID 23945614 DOI: 10.1039/C3Cc44569K |
0.309 |
|
| 2013 |
Patrick DA, Bakunov SA, Bakunova SM, Jones SK, Wenzler T, Barszcz T, Kumar A, Boykin DW, Werbovetz KA, Brun R, Tidwell RR. Synthesis and antiprotozoal activities of benzyl phenyl ether diamidine derivatives. European Journal of Medicinal Chemistry. 67: 310-24. PMID 23871911 DOI: 10.1016/J.Ejmech.2013.06.033 |
0.334 |
|
| 2013 |
Patrick DA, Ismail MA, Arafa RK, Wenzler T, Zhu X, Pandharkar T, Jones SK, Werbovetz KA, Brun R, Boykin DW, Tidwell RR. Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives. Journal of Medicinal Chemistry. 56: 5473-94. PMID 23795673 DOI: 10.1021/Jm400508E |
0.642 |
|
| 2013 |
Küster T, Kriegel N, Boykin DW, Stephens CE, Hemphill A. In vitro and in vivo activities of dicationic diguanidino compounds against Echinococcus multilocularis metacestodes. Antimicrobial Agents and Chemotherapy. 57: 3829-35. PMID 23716058 DOI: 10.1128/Aac.02569-12 |
0.344 |
|
| 2013 |
Liu ZY, Wang YM, Han YX, Liu L, Jin J, Yi H, Li ZR, Jiang JD, Boykin DW. Synthesis and antitumor activity of novel 3,4-diaryl squaric acid analogs. European Journal of Medicinal Chemistry. 65: 187-94. PMID 23708012 DOI: 10.1016/J.Ejmech.2013.04.046 |
0.347 |
|
| 2013 |
Nhili R, Peixoto P, Depauw S, Flajollet S, Dezitter X, Munde MM, Ismail MA, Kumar A, Farahat AA, Stephens CE, Duterque-Coquillaud M, David Wilson W, Boykin DW, David-Cordonnier MH. Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines. Nucleic Acids Research. 41: 125-38. PMID 23093599 DOI: 10.1093/Nar/Gks971 |
0.401 |
|
| 2013 |
Farahat AA, Boykin DW. Facile synthesis of aryl-pyridyl, pyridazinyl, pyrazinyl, and triazinyl acetonitriles Journal of Heterocyclic Chemistry. 50: 585-589. DOI: 10.1002/Jhet.1535 |
0.387 |
|
| 2012 |
Schorer M, Debache K, Barna F, Monney T, Müller J, Boykin DW, Stephens CE, Hemphill A. Di-cationic arylimidamides act against Neospora caninum tachyzoites by interference in membrane structure and nucleolar integrity and are active against challenge infection in mice. International Journal For Parasitology. Drugs and Drug Resistance. 2: 109-20. PMID 24533272 DOI: 10.1016/J.Ijpddr.2012.03.001 |
0.324 |
|
| 2012 |
Banerjee M, Farahat AA, Kumar A, Wenzler T, Brun R, Munde MM, Wilson WD, Zhu X, Werbovetz KA, Boykin DW. Synthesis, DNA binding and antileishmanial activity of low molecular weight bis-arylimidamides. European Journal of Medicinal Chemistry. 55: 449-54. PMID 22840696 DOI: 10.1016/J.Ejmech.2012.06.058 |
0.451 |
|
| 2012 |
Reid CS, Farahat AA, Zhu X, Pandharkar T, Boykin DW, Werbovetz KA. Antileishmanial bis-arylimidamides: DB766 analogs modified in the linker region and bis-arylimidamide structure-activity relationships. Bioorganic & Medicinal Chemistry Letters. 22: 6806-10. PMID 22765899 DOI: 10.1016/J.Bmcl.2012.06.037 |
0.354 |
|
| 2012 |
Rettig M, Germann MW, Ismail MA, Batista-Parra A, Munde M, Boykin DW, Wilson WD. Microscopic rearrangement of bound minor groove binders detected by NMR. The Journal of Physical Chemistry. B. 116: 5620-7. PMID 22530735 DOI: 10.1021/Jp301143E |
0.805 |
|
| 2012 |
Zhu X, Liu Q, Yang S, Parman T, Green CE, Mirsalis JC, de Nazaré Correia Soeiro M, Mello de Souza E, da Silva CF, da Gama Jaen Batista D, Stephens CE, Banerjee M, Farahat AA, Munde M, Wilson WD, ... Boykin DW, et al. Evaluation of arylimidamides DB1955 and DB1960 as candidates against visceral leishmaniasis and Chagas' disease: in vivo efficacy, acute toxicity, pharmacokinetics, and toxicology studies. Antimicrobial Agents and Chemotherapy. 56: 3690-9. PMID 22508306 DOI: 10.1128/Aac.06404-11 |
0.305 |
|
| 2012 |
Nanjunda R, Musetti C, Kumar A, Ismail MA, Farahat AA, Wang S, Sissi C, Palumbo M, Boykin DW, Wilson WD. Heterocyclic dications as a new class of telomeric G-quadruplex targeting agents. Current Pharmaceutical Design. 18: 1934-47. PMID 22380518 DOI: 10.2174/138161212799958422 |
0.395 |
|
| 2012 |
Liu Y, Chai Y, Kumar A, Tidwell RR, Boykin DW, Wilson WD. Designed compounds for recognition of 10 base pairs of DNA with two at binding sites. Journal of the American Chemical Society. 134: 5290-9. PMID 22369366 DOI: 10.1021/Ja211628J |
0.407 |
|
| 2012 |
da Silva CF, Batista Dda G, Oliveira GM, de Souza EM, Hammer ER, da Silva PB, Daliry A, Araujo JS, Britto C, Rodrigues AC, Liu Z, Farahat AA, Kumar A, Boykin DW, Soeiro Mde N. In vitro and in vivo investigation of the efficacy of arylimidamide DB1831 and its mesylated salt form--DB1965--against Trypanosoma cruzi infection. Plos One. 7: e30356. PMID 22291940 DOI: 10.1371/Journal.Pone.0030356 |
0.319 |
|
| 2012 |
Kropf C, Debache K, Rampa C, Barna F, Schorer M, Stephens CE, Ismail MA, Boykin DW, Hemphill A. The adaptive potential of a survival artist: characterization of the in vitro interactions of Toxoplasma gondii tachyzoites with di-cationic compounds in human fibroblast cell cultures. Parasitology. 139: 208-20. PMID 22011664 DOI: 10.1017/S0031182011001776 |
0.304 |
|
| 2012 |
Kader KFAE, Bialy SAAE, El-Ashmawy MB, Boykin DW. Pirfenidone structural isosteres: Design, synthesis and spectral study Heterocyclic Communications. 18: 193-197. DOI: 10.1515/Hc-2012-0117 |
0.358 |
|
| 2011 |
DA Silva CF, Daliry A, DA Silva PB, Akay S, Banerjee M, Farahat AA, Fisher MK, Hu L, Kumar A, Liu Z, Stephens CE, Boykin DW, Correia Soeiro MD. The efficacy of novel arylimidamides against Trypanosoma cruzi in vitro. Parasitology. 138: 1863-9. PMID 21902869 DOI: 10.1017/S0031182011001429 |
0.638 |
|
| 2011 |
Daliry A, Pires MQ, Silva CF, Pacheco RS, Munde M, Stephens CE, Kumar A, Ismail MA, Liu Z, Farahat AA, Akay S, Som P, Hu Q, Boykin DW, Wilson WD, et al. The trypanocidal activity of amidine compounds does not correlate with their binding affinity to Trypanosoma cruzi kinetoplast DNA. Antimicrobial Agents and Chemotherapy. 55: 4765-73. PMID 21807972 DOI: 10.1128/Aac.00229-11 |
0.64 |
|
| 2011 |
Stadelmann B, Küster T, Scholl S, Barna F, Kropf C, Keiser J, Boykin DW, Stephens CE, Hemphill A. In vitro efficacy of dicationic compounds and mefloquine enantiomers against Echinococcus multilocularis metacestodes. Antimicrobial Agents and Chemotherapy. 55: 4866-72. PMID 21768518 DOI: 10.1128/Aac.00478-11 |
0.376 |
|
| 2011 |
Collar CJ, Zhu X, Werbovetz K, Boykin DW, Wilson WD. Molecular factors governing inhibition of arylimidamides against Leishmania: conservative computational modeling to improve chemotherapies. Bioorganic & Medicinal Chemistry. 19: 4552-61. PMID 21741248 DOI: 10.1016/J.Bmc.2011.06.026 |
0.349 |
|
| 2011 |
Gillingwater K, Gutierrez C, Bridges A, Wu H, Deborggraeve S, Ekangu RA, Kumar A, Ismail M, Boykin D, Brun R. Efficacy study of novel diamidine compounds in a Trypanosoma evansi goat model. Plos One. 6: e20836. PMID 21698106 DOI: 10.1371/Journal.Pone.0020836 |
0.309 |
|
| 2011 |
Liu Y, Kumar A, Depauw S, Nhili R, David-Cordonnier MH, Lee MP, Ismail MA, Farahat AA, Say M, Chackal-Catoen S, Batista-Parra A, Neidle S, Boykin DW, Wilson WD. Water-mediated binding of agents that target the DNA minor groove. Journal of the American Chemical Society. 133: 10171-83. PMID 21627167 DOI: 10.1021/Ja202006U |
0.789 |
|
| 2011 |
Ismail MA, Boykin DW. SYNTHESIS OF NOVEL BITHIOPHENE-SUBSTITUTED HETEROCYCLES BEARING CARBONITRILE GROUPS. Synthetic Communications. 41: 319-330. PMID 21546984 DOI: 10.1080/00397910903537364 |
0.341 |
|
| 2011 |
Nehrbass-Stuedli A, Boykin D, Tidwell RR, Brun R. Novel diamidines with activity against Babesia divergens in vitro and Babesia microti in vivo. Antimicrobial Agents and Chemotherapy. 55: 3439-45. PMID 21537025 DOI: 10.1128/Aac.01482-10 |
0.365 |
|
| 2011 |
Farahat AA, Paliakov E, Kumar A, Barghash AE, Goda FE, Eisa HM, Wenzler T, Brun R, Liu Y, Wilson WD, Boykin DW. Exploration of larger central ring linkers in furamidine analogues: synthesis and evaluation of their DNA binding, antiparasitic and fluorescence properties. Bioorganic & Medicinal Chemistry. 19: 2156-67. PMID 21421317 DOI: 10.1016/J.Bmc.2011.02.045 |
0.445 |
|
| 2011 |
Hunt RA, Munde M, Kumar A, Ismail MA, Farahat AA, Arafa RK, Say M, Batista-Parra A, Tevis D, Boykin DW, Wilson WD. Induced topological changes in DNA complexes: influence of DNA sequences and small molecule structures. Nucleic Acids Research. 39: 4265-74. PMID 21266485 DOI: 10.1093/Nar/Gkq1362 |
0.787 |
|
| 2011 |
Ismail MA, Bialy SA, Brun R, Wenzler T, Nanjunda R, Wilson WD, Boykin DW. Dicationic phenyl-2,2'-bichalcophenes and analogues as antiprotozoal agents. Bioorganic & Medicinal Chemistry. 19: 978-84. PMID 21194955 DOI: 10.1016/J.Bmc.2010.11.047 |
0.412 |
|
| 2011 |
De Souza EM, da Silva PB, Nefertiti AS, Ismail MA, Arafa RK, Tao B, Nixon-Smith CK, Boykin DW, Soeiro MN. Trypanocidal activity and selectivity in vitro of aromatic amidine compounds upon bloodstream and intracellular forms of Trypanosoma cruzi. Experimental Parasitology. 127: 429-35. PMID 20971106 DOI: 10.1016/J.Exppara.2010.10.010 |
0.644 |
|
| 2011 |
Nanjunda RK, Liu Y, Wang L, Kumar A, Farahat A, Germann M, Boykin D, Wilson D. Solution Structure of a Novel Heterocyclic Dication Stacked as a Dimer with a Unique Mixed GC/AT Containing Motif Biophysical Journal. 100: 235a. DOI: 10.1016/J.Bpj.2010.12.1497 |
0.419 |
|
| 2011 |
Munde MM, Kumar A, Nhili R, Depauw S, David-Cordonnier M, Boykin D, Wilson D. Expanding DNA Sequence Recognition with Minor Groove Binders Biophysical Journal. 100: 234a-235a. DOI: 10.1016/J.Bpj.2010.12.1496 |
0.423 |
|
| 2010 |
Farahat AA, Kumar A, Barghash AE, Goda FE, Eisa HM, Boykin DW. Bichalcophenes: A Concise Synthesis of Formyl Ester- and Cyano Ester-Substituted Bithiophenes, Bifurans, and Furanothiophenes. Journal of Heterocyclic Chemistry. 47: 167-170. PMID 24634543 DOI: 10.1002/Jhet.295 |
0.339 |
|
| 2010 |
Munde M, Kumar A, Nhili R, Depauw S, David-Cordonnier MH, Ismail MA, Stephens CE, Farahat AA, Batista-Parra A, Boykin DW, Wilson WD. DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site. Journal of Molecular Biology. 402: 847-64. PMID 20713062 DOI: 10.1016/J.Jmb.2010.08.018 |
0.793 |
|
| 2010 |
Batista Dda G, Batista MM, de Oliveira GM, do Amaral PB, Lannes-Vieira J, Britto CC, Junqueira A, Lima MM, Romanha AJ, Sales Junior PA, Stephens CE, Boykin DW, Soeiro Mde N. Arylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatment. Antimicrobial Agents and Chemotherapy. 54: 2940-52. PMID 20457822 DOI: 10.1128/Aac.01617-09 |
0.314 |
|
| 2010 |
Branowska D, Farahat AA, Kumar A, Wenzler T, Brun R, Liu Y, Wilson WD, Boykin DW. Synthesis and antiprotozoal activity of 2,5-bis[amidinoaryl]thiazoles. Bioorganic & Medicinal Chemistry. 18: 3551-8. PMID 20403703 DOI: 10.1016/J.Bmc.2010.03.058 |
0.346 |
|
| 2010 |
Gillingwater K, Kumar A, Ismail MA, Arafa RK, Stephens CE, Boykin DW, Tidwell RR, Brun R. In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi. Veterinary Parasitology. 169: 264-72. PMID 20149544 DOI: 10.1016/J.Vetpar.2010.01.019 |
0.672 |
|
| 2010 |
Farahat AA, Kumar A, Say M, Barghash Ael-D, Goda FE, Eisa HM, Wenzler T, Brun R, Liu Y, Mickelson L, Wilson WD, Boykin DW. Synthesis, DNA binding, fluorescence measurements and antiparasitic activity of DAPI related diamidines. Bioorganic & Medicinal Chemistry. 18: 557-66. PMID 20031421 DOI: 10.1016/J.Bmc.2009.12.011 |
0.372 |
|
| 2010 |
Musetti C, Kumar A, Ismail MA, Lucatello L, Munde M, Nanjunda RK, Sissi C, Palumbo M, Boykin DW, Wilson WD. Abstract 3219: Heterocyclic cations: Highlighting the importance of selectivity in biologically relevant quadruplex DNA recognition and binding Cancer Research. 70: 3219-3219. DOI: 10.1158/1538-7445.Am10-3219 |
0.409 |
|
| 2009 |
Gillingwater K, Kumar A, Anbazhagan M, Boykin DW, Tidwell RR, Brun R. In vivo investigations of selected diamidine compounds against Trypanosoma evansi using a mouse model. Antimicrobial Agents and Chemotherapy. 53: 5074-9. PMID 19786604 DOI: 10.1128/Aac.00422-09 |
0.333 |
|
| 2009 |
Liu ZY, Wang YM, Li ZR, Jiang JD, Boykin DW. Synthesis and anticancer activity of novel 3,4-diarylthiazol-2(3H)-ones (imines). Bioorganic & Medicinal Chemistry Letters. 19: 5661-4. PMID 19713108 DOI: 10.1016/J.Bmcl.2009.08.025 |
0.316 |
|
| 2009 |
Hu L, Arafa RK, Ismail MA, Patel A, Munde M, Wilson WD, Wenzler T, Brun R, Boykin DW. Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum. Bioorganic & Medicinal Chemistry. 17: 6651-8. PMID 19699098 DOI: 10.1016/J.Bmc.2009.07.080 |
0.658 |
|
| 2009 |
Hu L, Kully ML, Boykin DW, Abood N. Synthesis and structure-activity relationship of dicationic diaryl ethers as novel potent anti-MRSA and anti-VRE agents. Bioorganic & Medicinal Chemistry Letters. 19: 4626-9. PMID 19589676 DOI: 10.1016/J.Bmcl.2009.06.077 |
0.345 |
|
| 2009 |
Tevis DS, Kumar A, Stephens CE, Boykin DW, Wilson WD. Large, sequence-dependent effects on DNA conformation by minor groove binding compounds. Nucleic Acids Research. 37: 5550-8. PMID 19578063 DOI: 10.1093/Nar/Gkp558 |
0.406 |
|
| 2009 |
Pacheco MG, da Silva CF, de Souza EM, Batista MM, da Silva PB, Kumar A, Stephens CE, Boykin DW, Soeiro Mde N. Trypanosoma cruzi: activity of heterocyclic cationic molecules in vitro. Experimental Parasitology. 123: 73-80. PMID 19520077 DOI: 10.1016/J.Exppara.2009.06.004 |
0.361 |
|
| 2009 |
Hu L, Kully ML, Boykin DW, Abood N. Optimization of the central linker of dicationic bis-benzimidazole anti-MRSA and anti-VRE agents. Bioorganic & Medicinal Chemistry Letters. 19: 3374-7. PMID 19481935 DOI: 10.1016/J.Bmcl.2009.05.061 |
0.363 |
|
| 2009 |
Hu L, Kully ML, Boykin DW, Abood N. Synthesis and in vitro activity of dicationic bis-benzimidazoles as a new class of anti-MRSA and anti-VRE agents. Bioorganic & Medicinal Chemistry Letters. 19: 1292-5. PMID 19208475 DOI: 10.1016/J.Bmcl.2009.01.075 |
0.336 |
|
| 2009 |
Rahimian M, Kumar A, Say M, Bakunov SA, Boykin DW, Tidwell RR, Wilson WD. Minor groove binding compounds that jump a gc base pair and bind to adjacent AT base pair sites. Biochemistry. 48: 1573-83. PMID 19173620 DOI: 10.1021/Bi801944G |
0.417 |
|
| 2009 |
Liu ZY, Li ZR, Jiang JD, Boykin DW. Synthesis of novel 4(Diarylmethylene)piperidines Heterocyclic Communications. 15: 401-405. DOI: 10.1515/Hc.2009.15.6.401 |
0.305 |
|
| 2009 |
Hu L, Boykin DW. A novel and convenient synthesis of 'reversed' diamidino 2,5-aryl- and 2,5-azaheterocycle-substituted furans Synthesis. 2143-2145. DOI: 10.1055/S-0029-1216817 |
0.313 |
|
| 2008 |
Liu Y, Collar CJ, Kumar A, Stephens CE, Boykin DW, Wilson WD. Heterocyclic diamidine interactions at AT base pairs in the DNA minor groove: effects of heterocycle differences, DNA AT sequence and length. The Journal of Physical Chemistry. B. 112: 11809-18. PMID 18717551 DOI: 10.1021/Jp804048C |
0.43 |
|
| 2008 |
da Silva CF, Batista MM, Batista Dda G, de Souza EM, da Silva PB, de Oliveira GM, Meuser AS, Shareef AR, Boykin DW, Soeiro Mde N. In vitro and in vivo studies of the trypanocidal activity of a diarylthiophene diamidine against Trypanosoma cruzi. Antimicrobial Agents and Chemotherapy. 52: 3307-14. PMID 18625779 DOI: 10.1128/Aac.00038-08 |
0.324 |
|
| 2008 |
Arafa RK, Ismail MA, Munde M, Wilson WD, Wenzler T, Brun R, Boykin DW. Novel linear triaryl guanidines, N-substituted guanidines and potential prodrugs as antiprotozoal agents. European Journal of Medicinal Chemistry. 43: 2901-8. PMID 18455271 DOI: 10.1016/J.Ejmech.2008.02.008 |
0.673 |
|
| 2008 |
Peixoto P, Liu Y, Depauw S, Hildebrand MP, Boykin DW, Bailly C, Wilson WD, David-Cordonnier MH. Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication. Nucleic Acids Research. 36: 3341-53. PMID 18440973 DOI: 10.1093/Nar/Gkn208 |
0.36 |
|
| 2008 |
Leepin A, Stüdli A, Brun R, Stephens CE, Boykin DW, Hemphill A. Host cells participate in the in vitro effects of novel diamidine analogues against tachyzoites of the intracellular apicomplexan parasites Neospora caninum and Toxoplasma gondii. Antimicrobial Agents and Chemotherapy. 52: 1999-2008. PMID 18362190 DOI: 10.1128/Aac.01236-07 |
0.303 |
|
| 2008 |
Wilson WD, Tanious FA, Mathis A, Tevis D, Hall JE, Boykin DW. Antiparasitic compounds that target DNA. Biochimie. 90: 999-1014. PMID 18343228 DOI: 10.1016/J.Biochi.2008.02.017 |
0.4 |
|
| 2008 |
Hu L, Arafa RK, Ismail MA, Wenzler T, Brun R, Munde M, Wilson WD, Nzimiro S, Samyesudhas S, Werbovetz KA, Boykin DW. Azaterphenyl diamidines as antileishmanial agents. Bioorganic & Medicinal Chemistry Letters. 18: 247-51. PMID 18006310 DOI: 10.1016/J.Bmcl.2007.10.091 |
0.667 |
|
| 2008 |
Ismail MA, Arafa RK, Wenzler T, Brun R, Tanious FA, Wilson WD, Boykin DW. Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines. Bioorganic & Medicinal Chemistry. 16: 683-91. PMID 17976993 DOI: 10.1016/J.Bmc.2007.10.042 |
0.649 |
|
| 2007 |
Hu L, Li ZR, Li JN, Qu J, Jiang JD, Boykin DW. 3-(2'-Bromopropionylamino)-benzamides as novel S-phase arrest agents. Bioorganic & Medicinal Chemistry Letters. 17: 6847-52. PMID 17977727 DOI: 10.1016/J.Bmcl.2007.10.016 |
0.305 |
|
| 2007 |
Munde M, Ismail MA, Arafa R, Peixoto P, Collar CJ, Liu Y, Hu L, David-Cordonnier MH, Lansiaux A, Bailly C, Boykin DW, Wilson WD. Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif. Journal of the American Chemical Society. 129: 13732-43. PMID 17935330 DOI: 10.1021/Ja074560A |
0.713 |
|
| 2007 |
Liu Y, Kumar A, Boykin DW, Wilson WD. Sequence and length dependent thermodynamic differences in heterocyclic diamidine interactions at AT base pairs in the DNA minor groove. Biophysical Chemistry. 131: 1-14. PMID 17889984 DOI: 10.1016/J.Bpc.2007.08.007 |
0.369 |
|
| 2007 |
Mathis AM, Bridges AS, Ismail MA, Kumar A, Francesconi I, Anbazhagan M, Hu Q, Tanious FA, Wenzler T, Saulter J, Wilson WD, Brun R, Boykin DW, Tidwell RR, Hall JE. Diphenyl furans and aza analogs: effects of structural modification on in vitro activity, DNA binding, and accumulation and distribution in trypanosomes. Antimicrobial Agents and Chemotherapy. 51: 2801-10. PMID 17517831 DOI: 10.1128/Aac.00005-07 |
0.42 |
|
| 2007 |
Hu L, Jiang JD, Qu J, Li Y, Jin J, Li ZR, Boykin DW. Novel potent antimitotic heterocyclic ketones: synthesis, antiproliferative activity, and structure-activity relationships. Bioorganic & Medicinal Chemistry Letters. 17: 3613-7. PMID 17482458 DOI: 10.1016/J.Bmcl.2007.04.048 |
0.355 |
|
| 2007 |
Munde M, Lee M, Neidle S, Arafa R, Boykin DW, Liu Y, Bailly C, Wilson WD. Induced fit conformational changes of a "reversed amidine" heterocycle: optimized interactions in a DNA minor groove complex. Journal of the American Chemical Society. 129: 5688-98. PMID 17425312 DOI: 10.1021/Ja069003N |
0.681 |
|
| 2007 |
Rosypal AC, Hall JE, Bakunova S, Patrick DA, Bakunov S, Stephens CE, Kumar A, Boykin DW, Tidwell RR. In vitro activity of dicationic compounds against a North American foxhound isolate of Leishmania infantum. Veterinary Parasitology. 145: 207-16. PMID 17298866 DOI: 10.1016/J.Vetpar.2007.01.005 |
0.356 |
|
| 2007 |
Hu L, Li ZR, Wang YM, Wu Y, Jiang JD, Boykin DW. Novel pyridinyl and pyrimidinylcarbazole sulfonamides as antiproliferative agents. Bioorganic & Medicinal Chemistry Letters. 17: 1193-6. PMID 17197178 DOI: 10.1016/J.Bmcl.2006.12.034 |
0.375 |
|
| 2007 |
Gonzalez JL, Stephens CE, Wenzler T, Brun R, Tanious FA, Wilson WD, Barszcz T, Werbovetz KA, Boykin DW. Synthesis and antiparasitic evaluation of bis-2,5-[4-guanidinophenyl]thiophenes. European Journal of Medicinal Chemistry. 42: 552-7. PMID 17178177 DOI: 10.1016/J.Ejmech.2006.11.006 |
0.313 |
|
| 2007 |
White EW, Tanious F, Ismail MA, Reszka AP, Neidle S, Boykin DW, Wilson WD. Structure-specific recognition of quadruplex DNA by organic cations: influence of shape, substituents and charge. Biophysical Chemistry. 126: 140-53. PMID 16831507 DOI: 10.1016/J.Bpc.2006.06.006 |
0.398 |
|
| 2007 |
Soeiro MdNC, de Souza EM, Boykin DW. Antiparasitic activity of aromatic diamidines and their patented literature Expert Opinion On Therapeutic Patents. 17: 927-939. DOI: 10.1517/13543776.17.8.927 |
0.347 |
|
| 2007 |
Paliakov E, Elleboe T, Boykin DW. New synthons for the preparation of arylimidazolines and tetrahydropyrimidine analogues Synthesis. 1475-1480. DOI: 10.1055/S-2007-966047 |
0.302 |
|
| 2006 |
Hu L, Li ZR, Li Y, Qu J, Ling YH, Jiang JD, Boykin DW. Synthesis and structure-activity relationships of carbazole sulfonamides as a novel class of antimitotic agents against solid tumors. Journal of Medicinal Chemistry. 49: 6273-82. PMID 17034133 DOI: 10.1021/Jm060546H |
0.335 |
|
| 2006 |
Ismail MA, Arafa RK, Brun R, Wenzler T, Miao Y, Wilson WD, Generaux C, Bridges A, Hall JE, Boykin DW. Synthesis, DNA affinity, and antiprotozoal activity of linear dications: Terphenyl diamidines and analogues. Journal of Medicinal Chemistry. 49: 5324-32. PMID 16913722 DOI: 10.1021/Jm060470P |
0.641 |
|
| 2006 |
Chackal-Catoen S, Miao Y, Wilson WD, Wenzler T, Brun R, Boykin DW. Dicationic DNA-targeted antiprotozoal agents: naphthalene replacement of benzimidazole. Bioorganic & Medicinal Chemistry. 14: 7434-45. PMID 16889966 DOI: 10.1016/J.Bmc.2006.07.024 |
0.419 |
|
| 2006 |
de Souza EM, Oliveira GM, Boykin DW, Kumar A, Hu Q, De Nazaré C Soeiro M. Trypanocidal activity of the phenyl-substituted analogue of furamidine DB569 against Trypanosoma cruzi infection in vivo. The Journal of Antimicrobial Chemotherapy. 58: 610-4. PMID 16854954 DOI: 10.1093/Jac/Dkl259 |
0.345 |
|
| 2006 |
Mathis AM, Holman JL, Sturk LM, Ismail MA, Boykin DW, Tidwell RR, Hall JE. Accumulation and intracellular distribution of antitrypanosomal diamidine compounds DB75 and DB820 in African trypanosomes. Antimicrobial Agents and Chemotherapy. 50: 2185-91. PMID 16723581 DOI: 10.1128/Aac.00192-06 |
0.37 |
|
| 2006 |
Athri P, Wenzler T, Ruiz P, Brun R, Boykin DW, Tidwell R, Wilson WD. 3D QSAR on a library of heterocyclic diamidine derivatives with antiparasitic activity. Bioorganic & Medicinal Chemistry. 14: 3144-52. PMID 16442293 DOI: 10.1016/J.Bmc.2005.12.029 |
0.36 |
|
| 2006 |
Ismail MA, Boykin DW, Stephens CE. An efficient synthesis of 5,5′-diaryl-2,2′-bichalcophenes Tetrahedron Letters. 47: 795-797. DOI: 10.1016/J.Tetlet.2005.11.091 |
0.328 |
|
| 2005 |
Miao Y, Lee MP, Parkinson GN, Batista-Parra A, Ismail MA, Neidle S, Boykin DW, Wilson WD. Out-of-shape DNA minor groove binders: induced fit interactions of heterocyclic dications with the DNA minor groove. Biochemistry. 44: 14701-8. PMID 16274217 DOI: 10.1021/bi051791q |
0.793 |
|
| 2005 |
Arafa RK, Brun R, Wenzler T, Tanious FA, Wilson WD, Stephens CE, Boykin DW. Synthesis, DNA affinity, and antiprotozoal activity of fused ring dicationic compounds and their prodrugs. Journal of Medicinal Chemistry. 48: 5480-8. PMID 16107146 DOI: 10.1021/Jm058190H |
0.69 |
|
| 2005 |
Wilson WD, Nguyen B, Tanious FA, Mathis A, Hall JE, Stephens CE, Boykin DW. Dications that target the DNA minor groove: compound design and preparation, DNA interactions, cellular distribution and biological activity. Current Medicinal Chemistry. Anti-Cancer Agents. 5: 389-408. PMID 16101490 DOI: 10.2174/1568011054222319 |
0.434 |
|
| 2005 |
Ismail MA, Batista-Parra A, Miao Y, Wilson WD, Wenzler T, Brun R, Boykin DW. Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents. Bioorganic & Medicinal Chemistry. 13: 6718-26. PMID 16099661 DOI: 10.1016/J.Bmc.2005.07.024 |
0.787 |
|
| 2005 |
Göker H, Ozden S, Yildiz S, Boykin DW. Synthesis and potent antibacterial activity against MRSA of some novel 1,2-disubstituted-1H-benzimidazole-N-alkylated-5-carboxamidines. European Journal of Medicinal Chemistry. 40: 1062-9. PMID 15992965 DOI: 10.1016/J.Ejmech.2005.05.002 |
0.347 |
|
| 2005 |
Göker H, Boykin DW, Yildiz S. Synthesis and potent antimicrobial activity of some novel 2-phenyl or methyl-4H-1-benzopyran-4-ones carrying amidinobenzimidazoles. Bioorganic & Medicinal Chemistry. 13: 1707-14. PMID 15698788 DOI: 10.1016/J.Bmc.2004.12.006 |
0.304 |
|
| 2005 |
Bailly C, Arafa RK, Tanious FA, Laine W, Tardy C, Lansiaux A, Colson P, Boykin DW, Wilson WD. Molecular determinants for DNA minor groove recognition: design of a bis-guanidinium derivative of ethidium that is highly selective for AT-rich DNA sequences. Biochemistry. 44: 1941-52. PMID 15697219 DOI: 10.1021/Bi047983N |
0.7 |
|
| 2004 |
Kang Z, Dykstra CC, Boykin DW. The synthesis of dicationic extended bis-benzimidazoles. Molecules (Basel, Switzerland). 9: 158-63. PMID 18007419 DOI: 10.3390/90300158 |
0.336 |
|
| 2004 |
Chaires JB, Ren J, Hamelberg D, Kumar A, Pandya V, Boykin DW, Wilson WD. Structural selectivity of aromatic diamidines Journal of Medicinal Chemistry. 47: 5729-5742. PMID 15509172 DOI: 10.1021/Jm049491E |
0.38 |
|
| 2004 |
Givens MD, Stringfellow DA, Dykstra CC, Riddell KP, Galik PK, Sullivan E, Robl J, Kasinathan P, Kumar A, Boykin DW. Prevention and elimination of bovine viral diarrhea virus infections in fetal fibroblast cells. Antiviral Research. 64: 113-8. PMID 15498606 DOI: 10.1016/J.Antiviral.2004.07.004 |
0.304 |
|
| 2004 |
Mallena S, Lee MP, Bailly C, Neidle S, Kumar A, Boykin DW, Wilson WD. Thiophene-based diamidine forms a "super" at binding minor groove agent. Journal of the American Chemical Society. 126: 13659-69. PMID 15493923 DOI: 10.1021/Ja048175M |
0.304 |
|
| 2004 |
Ismail MA, Brun R, Wenzler T, Tanious FA, Wilson WD, Boykin DW. Dicationic biphenyl benzimidazole derivatives as antiprotozoal agents. Bioorganic & Medicinal Chemistry. 12: 5405-13. PMID 15388167 DOI: 10.1016/J.Bmc.2004.07.056 |
0.409 |
|
| 2004 |
Crowell AL, Stephens CE, Kumar A, Boykin DW, Secor WE. Activities of dicationic compounds against Trichomonas vaginalis. Antimicrobial Agents and Chemotherapy. 48: 3602-5. PMID 15328138 DOI: 10.1128/Aac.48.9.3602-3605.2004 |
0.313 |
|
| 2004 |
Tanious FA, Hamelberg D, Bailly C, Czarny A, Boykin DW, Wilson WD. DNA Sequence Dependent Monomer-Dimer Binding Modulation of Asymmetric Benzimidazole Derivatives Journal of the American Chemical Society. 126: 143-153. PMID 14709078 DOI: 10.1021/Ja030403+ |
0.427 |
|
| 2004 |
Arafa RK, Brun R, Werbovetz KA, Tanious FA, David Wilson W, Boykin DW. Synthesis of dicationic 2,5-diarylpyrroles Heterocyclic Communications. 10: 423-428. DOI: 10.1515/Hc.2004.10.6.423 |
0.621 |
|
| 2004 |
Givens M, Stringfellow D, Riddell K, Galik P, Sullivan E, Robl J, Kasinathan P, Dykstra C, Boykin D. 196PREVENTION AND TREATMENT OF BOVINE VIRAL DIARRHEA VIRUS INFECTIONS IN
FETAL FIBROBLAST CELLS Reproduction, Fertility and Development. 16: 219. DOI: 10.1071/Rdv16N1Ab196 |
0.305 |
|
| 2004 |
Ismail MA, Boykin DW. Synthesis of deuterium-labelled 6-[5-(4-amidinophenyl)furan-2-yl]nicotinamidine and N-alkoxy-6-{5-[4-(N-alkoxyamidino)phenyl]-furan-2-yl}-nicotinamidines Journal of Labelled Compounds and Radiopharmaceuticals. 47: 233-242. DOI: 10.1002/Jlcr.817 |
0.309 |
|
| 2003 |
Hranjec M, Grdiša M, Pavelic K, Boykin DW, Karminski-Zamola G. Synthesis and antitumor evaluation of some new substituted amidino-benzimidazolyl-furyl-phenyl-acrylates and naphtho[2,1-b]furan- carboxylates Farmaco. 58: 1319-1324. PMID 14630246 DOI: 10.1016/S0014-827X(03)00197-6 |
0.329 |
|
| 2003 |
Rowland EC, Moore-Lai D, Seed JR, Stephens CE, Boykin DW. Inhibition of in vitro intracellular growth of Trypanosoma cruzi by dicationic compounds. The Journal of Parasitology. 89: 1078-80. PMID 14627166 DOI: 10.1645/Ge-53R |
0.384 |
|
| 2003 |
Tanious F, Wilson WD, Wang L, Kumar A, Boykin DW, Marty C, Baldeyrou B, Bailly C. Cooperative Dimerization of a Heterocyclic Diamidine Determines Sequence-Specific DNA Recognition Biochemistry. 42: 13576-13586. PMID 14622004 DOI: 10.1021/Bi034852Y |
0.384 |
|
| 2003 |
Ismail MA, Brun R, Easterbrook JD, Tanious FA, Wilson WD, Boykin DW. Synthesis and antiprotozoal activity of aza-analogues of furamidine. Journal of Medicinal Chemistry. 46: 4761-9. PMID 14561095 DOI: 10.1021/Jm0302602 |
0.351 |
|
| 2003 |
Givens MD, Dykstra CC, Brock KV, Stringfellow DA, Kumar A, Stephens CE, Goker H, Boykin DW. Detection of inhibition of bovine viral diarrhea virus by aromatic cationic molecules Antimicrobial Agents and Chemotherapy. 47: 2223-2230. PMID 12821472 DOI: 10.1128/Aac.47.7.2223-2230.2003 |
0.319 |
|
| 2003 |
Stephens CE, Brun R, Salem MM, Werbovetz KA, Tanious F, Wilson WD, Boykin DW. The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani Bioorganic and Medicinal Chemistry Letters. 13: 2065-2069. PMID 12781196 DOI: 10.1016/S0960-894X(03)00319-6 |
0.327 |
|
| 2003 |
Batista-Parra A, Venkitachalam S, Wilson WD, Boykin DW. Synthesis of 2-(5-amidinobenzoxazol-2-YL)-5-(4-amidino- phenyl)furan and 2-(5-amidinobenzoxazol-2-YL)-5-(4-amidinophenyl)thiphene to test a DNA minor groove dimer binding model Heterocycles. 60: 1367-1376. DOI: 10.3987/Com-03-9747 |
0.792 |
|
| 2003 |
Racanè L, Tralić-Kulenović V, Boykin DW, Karminski-Zamola G. Synthesis of new cyano-substituted bis-benzothiazolyl arylfurans and arylthiophenes Molecules. 8: 342-349. DOI: 10.3390/80300342 |
0.363 |
|
| 2003 |
Starčević K, Boykin DW, Karminski-Zamola G. New amidino-benzimidazolyl thiophenes: Synthesis and photochemical synthesis Heteroatom Chemistry. 14: 218-222. DOI: 10.1002/Hc.10126 |
0.407 |
|
| 2002 |
Lansiaux A, Tanious F, Mishal Z, Dassonneville L, Kumar A, Stephens CE, Hu Q, Wilson WD, Boykin DW, Bailly C. Distribution of furamidine analogues in tumor cells: Targeting of the nucleus or mitochondria depending on the amidine substitution Cancer Research. 62: 7219-7229. PMID 12499262 |
0.306 |
|
| 2002 |
Göker H, Kuş C, Boykin DW, Yildiz S, Altanlar N. Synthesis of some new 2-substituted-phenyl-1H-benzimidazole-5-carbonitriles and their potent activity against Candida species Bioorganic and Medicinal Chemistry. 10: 2589-2596. PMID 12057648 DOI: 10.1016/S0968-0896(02)00103-7 |
0.357 |
|
| 2002 |
Lansiaux A, Dassonneville L, Facompré M, Kumar A, Stephens CE, Bajic M, Tanious F, Wilson DW, Boykin DW, Bailly C. Distribution of furamidine analogues in tumor cells: Influence of the number of positive charges Journal of Medicinal Chemistry. 45: 1994-2002. PMID 11985467 DOI: 10.1021/Jm010539N |
0.418 |
|
| 2002 |
Wang L, Kumar A, Boykin DW, Bailly C, Wilson WD. Comparative thermodynamics for monomer and dimer sequence-dependent binding of a heterocyclic dication in the DNA minor groove Journal of Molecular Biology. 317: 361-374. PMID 11922670 DOI: 10.1006/Jmbi.2002.5433 |
0.425 |
|
| 2002 |
Nguyen B, Tardy C, Bailly C, Colson P, Houssier C, Kumar A, Boykin DW, Wilson WD. Influence of compound structure on affinity, sequence selectivity, and mode of binding to DNA for unfused aromatic dications related to furamidine Biopolymers. 63: 281-297. PMID 11877739 DOI: 10.1002/Bip.10073 |
0.445 |
|
| 2002 |
Brendle JJ, Outlaw A, Kumar A, Boykin DW, Patrick DA, Tidwell RR, Werbovetz KA. Antileishmanial activities of several classes of aromatic dications Antimicrobial Agents and Chemotherapy. 46: 797-807. PMID 11850264 DOI: 10.1128/Aac.46.3.797-807.2002 |
0.356 |
|
| 2002 |
Boykin DW. Antimicrobial activity of the DNA minor groove binders furamidine and analogs Journal of the Brazilian Chemical Society. 13: 763-771. DOI: 10.1590/S0103-50532002000600006 |
0.372 |
|
| 2002 |
Starčević K, Boykin DW, Karminski-Zamola G. New amidino-substituted benzimidazolyl furyl-thienyl-acrylates and benzothienofurans; Synthesis and photochemical synthesis Heterocyclic Communications. 8: 221-226. DOI: 10.1515/Hc.2002.8.3.221 |
0.4 |
|
| 2001 |
Bilik P, Tanious F, Kumar A, Wilson WD, Boykin DW, Colson P, Houssier C, Facompré M, Tardy C, Bailly C. Novel dications with unfused aromatic systems: Trithiophene and trifuran derivatives of furimidazoline Chembiochem. 2: 559-569. PMID 11828489 DOI: 10.1002/1439-7633(20010803)2:7/8<559::Aid-Cbic559>3.0.Co;2-U |
0.425 |
|
| 2001 |
Xiao G, Kumar A, Li K, Rigl CT, Bajic M, Davis TM, Boykin DW, Wilson WD. Inhibition of the HIV-1 Rev-RRE complex formation by unfused aromatic cations Bioorganic and Medicinal Chemistry. 9: 1097-1113. PMID 11377168 DOI: 10.1016/S0968-0896(00)00344-8 |
0.341 |
|
| 2001 |
Stephens CE, Tanious F, Kim S, Wilson WD, Schell WA, Perfect JR, Franzblau SG, Boykin DW. Diguanidino and "reversed" diamidino 2,5-diarylfurans as antimicrobial agents Journal of Medicinal Chemistry. 44: 1741-1748. PMID 11356109 DOI: 10.1021/Jm000413A |
0.431 |
|
| 2001 |
Wang L, Carrasco C, Kumar A, Stephens CE, Bailly C, Boykin DW, Wilson WD. Evaluation of the influence of compound structure on stacked-dimer formation in the DNA minor groove Biochemistry. 40: 2511-2521. PMID 11327873 DOI: 10.1021/bi002301r |
0.339 |
|
| 2001 |
Boykin DW, Göker H. Ring cleavage of dicyano-substituted benzimidazoles by Dibal Heterocyclic Communications. 7: 529-534. DOI: 10.1515/Hc.2001.7.6.529 |
0.304 |
|
| 2000 |
Simpson IJ, Lee M, Kumar A, Boykin DW, Neidle S. DNA minor groove interactions and the biological activity of 2,5-bis-[4-(N-alkylamidino)phenyl] furans Bioorganic and Medicinal Chemistry Letters. 10: 2593-2597. PMID 11128631 DOI: 10.1016/S0960-894X(00)00511-4 |
0.402 |
|
| 2000 |
Mazur S, Tanious FA, Ding D, Kumar A, Boykin DW, Simpson IJ, Neidle S, Wilson WD. A thermodynamic and structural analysis of DNA minor-groove complex formation. Journal of Molecular Biology. 300: 321-37. PMID 10873468 DOI: 10.1006/Jmbi.2000.3869 |
0.4 |
|
| 2000 |
Wang L, Bailly C, Kumar A, Ding D, Bajic M, Boykin DW, Wilson WD. Specific molecular recognition of mixed nucleic acid sequences: an aromatic dication that binds in the DNA minor groove as a dimer. Proceedings of the National Academy of Sciences of the United States of America. 97: 12-6. PMID 10618362 DOI: 10.1073/Pnas.97.1.12 |
0.43 |
|
| 1999 |
Rahmathullah SM, Hall JE, Bender BC, McCurdy DR, Tidwell RR, Boykin DW. Prodrugs for amidines: Synthesis and anti-Pneumocystis carinii activity of carbamates of 2,5-bis(4-amidinophenyl)furan Journal of Medicinal Chemistry. 42: 3994-4000. PMID 10508447 DOI: 10.1021/Jm990237+ |
0.365 |
|
| 1999 |
Del Poeta M, Bixel AS, Barchiesi F, Tidwell RR, Boykin D, Scalise G, Perfect JR. In-vitro activity of dicationic aromatic compounds and fluconazole against Cryptococcus neoformans and Candida spp Journal of Antimicrobial Chemotherapy. 44: 223-228. PMID 10473229 DOI: 10.1093/Jac/44.2.223 |
0.353 |
|
| 1999 |
Gelus N, Bailly C, Hamy F, Klimkait T, Wilson WD, Boykin DW. Inhibition of HIV-1 Tat-TAR interaction by diphenylfuran derivatives: effects of the terminal basic side chains. Bioorganic & Medicinal Chemistry. 7: 1089-1096. PMID 10428378 DOI: 10.1016/S0968-0896(99)00041-3 |
0.317 |
|
| 1998 |
Blagburn BL, Drain KL, Land TM, Kinard RG, Moore PH, Lindsay DS, Patrick DA, Boykin DW, Tidwell RR. Comparative efficacy evaluation of dicationic carbazole compounds, nitazoxanide, and paromomycin against Cryptosporidium parvum infections in a neonatal mouse model. Antimicrobial Agents and Chemotherapy. 42: 2877-82. PMID 9797219 DOI: 10.1128/Aac.42.11.2877 |
0.304 |
|
| 1998 |
Del Poeta M, Schell WA, Dykstra CC, Jones SK, Tidwell RR, Kumar A, Boykin DW, Perfect JR. In vitro antifungal activities of a series of dication-substituted carbazoles, furans, and benzimidazoles. Antimicrobial Agents and Chemotherapy. 42: 2503-10. PMID 9756748 DOI: 10.1128/Aac.42.10.2503 |
0.367 |
|
| 1998 |
Del Poeta M, Schell WA, Dykstra CC, Jones S, Tidwell RR, Czarny A, Bajic M, Kumar A, Boykin D, Perfect JR. Structure-in vitro activity relationships of pentamidine analogues and dication-substituted bis-benzimidazoles as new antifungal agents Antimicrobial Agents and Chemotherapy. 42: 2495-2502. PMID 9756747 DOI: 10.1128/Aac.42.10.2495 |
0.362 |
|
| 1998 |
Hildebrandt E, Boykin DW, Kumar A, Tidwell RR, Dykstra CC. Identification and characterization of an endo/exonuclease in Pneumocystis carinii that is inhibited by dicationic diarylfurans with efficacy against Pneumocystis pneumonia. The Journal of Eukaryotic Microbiology. 45: 112-21. PMID 9495040 DOI: 10.1111/J.1550-7408.1998.Tb05078.X |
0.374 |
|
| 1998 |
Boykin DW, Kumar A, Xiao G, Wilson WD, Bender BC, McCurdy DR, Hall JE, Tidwell RR. 2,5-bis[4-(N-alkylamidino)phenyl]furans as anti-Pneumocystis carinii agents. Journal of Medicinal Chemistry. 41: 124-9. PMID 9438029 DOI: 10.1021/Jm970570I |
0.422 |
|
| 1998 |
Wilson WD, Tanious FA, Ding D, Kumar A, Boykin DW, Colson P, Houssier C, Bailly C. Nucleic Acid Interactions of Unfused Aromatic Cations: Evaluation of Proposed Minor-Groove, Major-Groove, and Intercalation Binding Modes Journal of the American Chemical Society. 120: 10310-10321. DOI: 10.1021/Ja981212N |
0.4 |
|
| 1998 |
Perumal S, Vasuki G, Vijayabaskar V, Selvaraj S, Boykin DW. 1H, 13C and 17O NMR study of substituent effects in 4-substituted phenylthiol esters Magnetic Resonance in Chemistry. 36: 720-726. DOI: 10.1002/(Sici)1097-458X(199810)36:10<720::Aid-Omr357>3.0.Co;2-0 |
0.311 |
|
| 1997 |
Fernandez-Saiz KLM, Rigl CT, Kumar A, Ragunathan KG, McConnaughie AW, Boykin DW, Schneider H, Wilson WD. Design and analysis of molecular motifs for specific recognition of RNA. Bioorganic & Medicinal Chemistry. 5: 1157-1172. PMID 9222510 DOI: 10.1016/S0968-0896(97)00054-0 |
0.307 |
|
| 1997 |
Zapp ML, Young DW, Kumar A, Singh R, Boykin DW, Wilson WD, Green MR. Modulation of the Rev-RRE interaction by aromatic heterocyclic compounds. Bioorganic & Medicinal Chemistry. 5: 1149-55. PMID 9222509 DOI: 10.1016/S0968-0896(97)00063-1 |
0.31 |
|
| 1997 |
Clark GR, Boykin DW, Czarny A, Neidle S. Structure of a bis-amidinium derivative of hoechst 33258 complexed to dodecanucleotide d(CGCGAATTCGCG)2: the role of hydrogen bonding in minor groove drug-DNA recognition. Nucleic Acids Research. 25: 1510-5. PMID 9162901 DOI: 10.1093/Nar/25.8.1510 |
0.333 |
|
| 1997 |
Karminski-Zamola G, Tralić-Kulenović V, Fiser-Jakić L, Bajic M, Boykin DW. Electron impact mass spectra of some bis-(2-benzothiazolyl)furans and bis-(2-benzothiazolyl)thiophenes. Rapid Communications in Mass Spectrometry : Rcm. 10: 1621-5. PMID 8914336 DOI: 10.1002/(Sici)1097-0231(199610)10:13<1621::Aid-Rcm619>3.0.Co;2-R |
0.35 |
|
| 1997 |
Wilson WD, Ratmeyer L, Zhao M, Ding D, McConnaughie AW, Kumar A, Boykin DW. Design and analysis of RNA structure-specific agents as potential antivirals. Journal of Molecular Recognition : Jmr. 9: 187-96. PMID 8877812 DOI: 10.1002/(Sici)1099-1352(199603)9:2<187::Aid-Jmr259>3.0.Co;2-H |
0.345 |
|
| 1997 |
De Rosa M, Boykin DW, Baumstark AL. 17O NMR study of substituent effects in 4-substituted N-chlorobenzamides and comparison with 4-substituted benzamides: Sensitivity to ring substituents (ρ) reflects electronic and steric effects Journal of the Chemical Society. Perkin Transactions 2. 1547-1549. DOI: 10.1039/A700206H |
0.32 |
|
| 1996 |
Bajic M, Kumar A, Boykin DW. SYNTHESIS OF 2,5-Bis-(4-CYANOPHENYL)-FURAN Heterocyclic Communications. 2. DOI: 10.1515/Hc.1996.2.2.135 |
0.307 |
|
| 1996 |
Perjéssy A, Rasala D, Gawinecki R, Boykin DW. Assessment of substituent effects for ortho-nitrobenzenes and 2,4- dinitrobenzenes by IR and 17O NMR spectroscopy Journal of Molecular Structure. 382: 93-99. DOI: 10.1016/0022-2860(96)09256-3 |
0.318 |
|
| 1995 |
Boykin DW, Kumar A, Spychala J, Zhou M, Lombardy RJ, Wilson WD, Dykstra CC, Jones SK, Hall JE, Tidwell RR. Dicationic diarylfurans as anti-Pneumocystis carinii agents. Journal of Medicinal Chemistry. 38: 912-6. PMID 7699707 DOI: 10.1021/jm00006a009 |
0.309 |
|
| 1995 |
Zhao M, Ratmeyer L, Peloquin RG, Yao S, Kumar A, Spychala J, Boykin DW, Wilson WD. Small changes in cationic substituents of diphenylfuran derivatives have major effects on the binding affinity and the binding mode with RNA helical duplexes. Bioorganic & Medicinal Chemistry. 3: 785-94. PMID 7582956 DOI: 10.1016/0968-0896(95)00057-N |
0.338 |
|
| 1995 |
Wood AA, Nunn CM, Czarny A, Boykin DW, Neidle S. Variability in DNA minor groove width recognised by ligand binding: the crystal structure of a bis-benzimidazole compound bound to the DNA duplex d(CGCGAATTCGCG)2. Nucleic Acids Research. 23: 3678-84. PMID 7478996 DOI: 10.1093/Nar/23.18.3678 |
0.43 |
|
| 1995 |
Bajic M, Boykin DW. SYNTHESIS OF 2,4-BIS [4-(5-AMIDINO AND 5-SUBSTITUTEDAMIDINO-2-BENZIMIDAZOYL) PYRIMIDINES Heterocyclic Communications. 1. DOI: 10.1515/Hc.1995.1.4.225 |
0.314 |
|
| 1994 |
Tanious FA, Spychala J, Kumar A, Greene K, Boykin DW, Wilson WD. Different binding mode in AT and GC sequences for unfused-aromatic dications. Journal of Biomolecular Structure & Dynamics. 11: 1063-83. PMID 7946061 DOI: 10.1080/07391102.1994.10508053 |
0.423 |
|
| 1994 |
McConnaughie AW, Spychala J, Zhao M, Boykin D, David Wilson W. Design and synthesis of RNA-specific groove-binding cations: Implications for antiviral drug design Journal of Medicinal Chemistry. 37: 1063-1069. PMID 7513027 DOI: 10.1021/Jm00034A004 |
0.323 |
|
| 1994 |
Kumar A, Zhao M, David Wilson W, Boykin DW. Dicatonic 2,4-diaryl pyrimidines as DNA selective binding agents Bioorganic & Medicinal Chemistry Letters. 4: 2913-2918. DOI: 10.1016/S0960-894X(01)80839-8 |
0.358 |
|
| 1992 |
Perumal S, Vasuki G, Wilson DA, Boykin DW. 1H,13C and17O NMR spectral study of 4,1-disubstituted naphthalenes Magnetic Resonance in Chemistry. 30: 320-326. DOI: 10.1002/Mrc.1260300409 |
0.344 |
|
| 1991 |
Hopkins HP, Ming Y, Wilson WD, Boykin DW. Intercalation binding of 6-substituted naphthothiopheneamides to DNA: Enthalpy and entropy components Biopolymers. 31: 1105-1114. PMID 1723899 DOI: 10.1002/Bip.360310910 |
0.439 |
|
| 1991 |
Boykin DW, Nowak-Wydra B. 17O NMR spectroscopic study of substituted 9-fluorenones Magnetic Resonance in Chemistry. 29: 152-155. DOI: 10.1002/Mrc.1260290211 |
0.306 |
|
| 1991 |
Boykin DW, Nowak-Wydra B, Baumstark AL. Synthesis of bis-2,7-substituted 1,2,3,6,7,8-hexahydroisoindolo[5,6-f]isoindole-1,3,6,8-tetraones Journal of Heterocyclic Chemistry. 28: 609-611. DOI: 10.1002/Jhet.5570280313 |
0.318 |
|
| 1990 |
Wilson WD, Chandrasekaran S, Kusuma S, Boykin DW, Neidle S. The influence of intercalator structure on DNA binding strength: the importance of side chain orientation. Journal of Biomolecular Structure & Dynamics. 5: 327-44. PMID 3271478 DOI: 10.1080/07391102.1987.10506398 |
0.303 |
|
| 1990 |
Boykin DW. Natural Abudance17O NMR Studies of Thiol Esters and Related Analogs Spectroscopy Letters. 23: 1133-1140. DOI: 10.1080/00387019008054487 |
0.335 |
|
| 1989 |
Fairley T, Molock F, Boykin DW, Wilson WD. The interaction of multiply charged intercalating heterocycles with DNA. Biopolymers. 27: 1433-47. PMID 3219405 DOI: 10.1002/Bip.360270909 |
0.402 |
|
| 1989 |
Wilson WD, Tanious FA, Barton HJ, Jones RL, Strekowski L, Boykin DW. Binding of 4',6-diamidino-2-phenylindole (DAPI) to GC and mixed sequences in DNA: intercalation of a classical groove-binding molecule Journal of the American Chemical Society. 111: 5008-5010. DOI: 10.1021/Ja00195A080 |
0.354 |
|
| 1987 |
Boykin DW, Baumstark AL, Kayser MM, Soucy CM. 17O nuclear magnetic resonance spectroscopic study of substituted phthalic anhydrides and phthalides Canadian Journal of Chemistry. 65: 1214-1217. DOI: 10.1139/V87-204 |
0.33 |
|
| 1987 |
Baumstark AL, Balakrishnan P, Dotrong M, McCloskey CJ, Oakley MG, Boykin DW. Oxygen-17 NMR spectroscopy: torsion angle relationships in aryl carboxylic esters, acids and amides Journal of the American Chemical Society. 109: 1059-1062. DOI: 10.1021/Ja00238A013 |
0.312 |
|
| 1987 |
Wysocki MA, Jardon PW, Mains GJ, Eisenbraun EJ, Boykin DW. Steric effects in the17O NMR spectroscopy of aromatic methyl ethers Magnetic Resonance in Chemistry. 25: 331-334. DOI: 10.1002/Mrc.1260250412 |
0.4 |
|
| 1987 |
Boykin DW, Balakrishnan P, Baumstark AL. 17O NMR studies of torsion angle relationships in aryl alkyl ketones and aromatic aldehydes Magnetic Resonance in Chemistry. 25: 248-250. DOI: 10.1002/Mrc.1260250314 |
0.349 |
|
| 1987 |
Boykin DW, Martin GE. 17O NMR Investigation of cyclic aromatic ethers Journal of Heterocyclic Chemistry. 24: 365-367. DOI: 10.1002/Jhet.5570240214 |
0.327 |
|
| 1986 |
Wilson WD, Wang YH, Kusuma S, Chandrasekaran S, Boykin DW. The effect of intercalator structure on binding strength and base-pair specificity in DNA interactions. Biophysical Chemistry. 24: 101-9. PMID 3756304 DOI: 10.1016/0301-4622(86)80003-5 |
0.437 |
|
| 1986 |
Chandrasekaran S, Kusuma S, Boykin DW, Wilson WD. A new approach utilizing high-resolution proton NMR in structural analysis of intercalation complexes of natural DNA Magnetic Resonance in Chemistry. 24: 630-637. DOI: 10.1002/Mrc.1260240713 |
0.375 |
|
| 1986 |
Balakrishnan P, Boykin DW. Natural abundance17O NMR spectroscopy of heteroaromatic Nitro compounds Journal of Heterocyclic Chemistry. 23: 191-192. DOI: 10.1002/Jhet.5570230140 |
0.326 |
|
| 1985 |
Kitchen SE, Wang YH, Baumstark AL, Wilson WD, Boykin DW. The intercalation of 6-chloro-substituted-9-[[3-(dimethylamino)propyl]amino]acridines with DNA. Journal of Medicinal Chemistry. 28: 940-4. PMID 4009616 DOI: 10.1021/Jm00145A016 |
0.394 |
|
| 1985 |
Boykin DW, Baumstark AL, Balakrishnan P. 17O NMR spectroscopy of 4-substituted pyridineN-oxides: Substituent and solvent effects Magnetic Resonance in Chemistry. 23: 276-279. DOI: 10.1002/Mrc.1260230414 |
0.306 |
|
| 1985 |
Kusuma S, Wilson WD, Boykin DW. Synthesis of 8-substituted naphtho[2,1-b]thiophenes with cationic side chains at position 4 Journal of Heterocyclic Chemistry. 22: 1229-1232. DOI: 10.1002/Jhet.5570220518 |
0.324 |
|
| 1985 |
Wilson WD, Wang YH, Kusuma S, Chandrasekaran S, Yang NC, Boykin DW. Binding strength and specificity in DNA interactions: the design of A.cntdot.T specific intercalators Journal of the American Chemical Society. 107: 4989-4995. DOI: 10.1002/Chin.198549058 |
0.327 |
|
| 1985 |
Kitchen SE, Wang Y-, Baumstark AL, Wilson WD, Boykin DW. The Intercalation Of 6-Chloro-2-Substituted-9-((3-(Dimethylamino)Propyl)Amino)Acridines With Dna Cheminform. 16. DOI: 10.1002/Chin.198544184 |
0.366 |
|
| 1984 |
Stevenson KA, Yen SF, Yang NC, Boykin DW, David Wilson W. A substituent constant analysis of the interaction of substituted naphthalene monoimides with DNA Journal of Medicinal Chemistry. 27: 1677-1682. PMID 6502597 DOI: 10.1021/jm00378a026 |
0.329 |
|
| 1984 |
Chandrasekaran S, Wilson WD, Boykin DW. 17O NMR studies on polycyclic quinones, hydroxyquinones and related cyclic ketones: Models for anthracycline intercalators Organic Magnetic Resonance. 22: 757-760. DOI: 10.1002/Mrc.1270221205 |
0.322 |
|
| 1983 |
Molock FF, Boykin DW. The synthesis of pyridoquinolines with dialkylaminopropylamine side chains Journal of Heterocyclic Chemistry. 20: 681-686. DOI: 10.1002/Jhet.5570200335 |
0.358 |
|
| 1982 |
Das BP, Zalkow VB, Forrester ML, Molock FF, Boykin DW. 1,4-Bis(4-guanylphenylethyl)benzenes as potential antitrypanosomal agents Journal of Pharmaceutical Sciences. 71: 465-466. PMID 7086662 DOI: 10.1002/Chin.198239205 |
0.369 |
|
| 1982 |
Lopp IG, Wilson WD, Boykin DW. The synthesis of a potential bisintercalating ethidium bromide analog Journal of Heterocyclic Chemistry. 19: 695-696. DOI: 10.1002/Jhet.5570190355 |
0.334 |
|
| 1980 |
Das BP, Wallace RA, Boykin DW. Synthesis and antitrypanosomal activity of some bis(4-guanylphenyl) five and six-membered ring heterocycles Journal of Medicinal Chemistry. 23: 578-581. PMID 7381860 DOI: 10.1021/Jm00179A022 |
0.355 |
|
| 1980 |
Baumstark AL, Chrisope DR, Keel RA, Boykin DW. A carbon-13 Nmr assignment study of 3,5-diarylisoxazoles Journal of Heterocyclic Chemistry. 17: 1719-1721. DOI: 10.1002/Jhet.5570170815 |
0.302 |
|
| 1979 |
Perjéssy A, Temkovitz P, Boykin DW. The C=O stretching vibration of aromaric α,β-unsaturated carbonyl and arylfurancarbonyl compounds Collection of Czechoslovak Chemical Communications. 44: 2832-2842. DOI: 10.1135/Cccc19792832 |
0.303 |
|
| 1979 |
Sawhney SN, Boykin DW. A reinvestigation of the bamberger-ham phenazine. Synthesis: A limitation Journal of Heterocyclic Chemistry. 16: 397-400. DOI: 10.1002/Jhet.5570160243 |
0.342 |
|
| 1978 |
Davidson MW, Griggs BG, Boykin DW, Wilson WD. Molecular structural effects involved in the interaction of quinolinemethanolamines with DNA. Implications for antimalarial action. Journal of Medicinal Chemistry. 20: 1117-22. PMID 926111 DOI: 10.1002/Chin.197752247 |
0.313 |
|
| 1977 |
Das BP, Boykin DW. Synthesis and antiprotozoal activity of 2,5-bis(4-guanylphenyl)thiophenes and -pyrroles Journal of Medicinal Chemistry. 20: 1219-1221. PMID 336890 DOI: 10.1002/Chin.197752224 |
0.312 |
|
| 1977 |
Das BP, Boykin DW. Synthesis and antiprotozoal activity of 2,5-bis(4-guanylphenyl)furans Journal of Medicinal Chemistry. 20: 531-536. PMID 321783 DOI: 10.1002/Chin.197735199 |
0.398 |
|
| 1975 |
Davidson MW, Griggs BG, Boykin DW, Wilson WD. Mefloquine, a clinically useful quinolinemethanol antimalarial which does not significantly bind to DNA. Nature. 254: 632-634. PMID 1128663 DOI: 10.1038/254632A0 |
0.376 |
|
| 1975 |
Olmstead EJ, Panter JW, Boykin DW, Wilson WD. Complex formation between naphthothiopheneethanolamines and deoxyribonucleic acids Biochemistry. 14: 521-526. PMID 1111568 DOI: 10.1021/Bi00674A010 |
0.38 |
|
| 1975 |
Juelke CV, Boykin DW, Dale JI, Lutz RE. Phenyl group migration during pyrolytic and photolytic deazotizations of 1,2-bis-2-(phenylated 2,5-dihydrofuranyl)hydrazines to .beta.,.gamma.-unsaturated ketones The Journal of Organic Chemistry. 40: 545-552. DOI: 10.1021/Jo00893A001 |
0.5 |
|
| 1975 |
Juelke CV, Boykin DW, Dale JI, Lutz RE. Phenyl group migration during pyrolytic and photolytic deazotizations of 1,2-bis[2-(phenylated 2,5-dihydrofuranyl)]hydrazines to β,γ-unsaturated ketones1-33-c,4a Journal of Organic Chemistry. 40: 545-552. |
0.462 |
|
| 1974 |
Das BP, Boykin DW. Synthesis of 2,4-diamino-5-[4-arylthiophenyl]- and 5-[4-arylsulfonylphenyl]pyrimidines as antimalarials Journal of Medicinal Chemistry. 17: 372-374. PMID 4590245 DOI: 10.1021/Jm00249A031 |
0.307 |
|
| 1973 |
PERJESSY A, BOYKIN DW, FISERA L, KRUTOSIKOVA A, KOVAC J. ChemInform Abstract: CARBONYL-STRECKSCHWINGUNGEN UND UEBERTRAGUNG ELEKTRONISCHER EFFEKTE BEI 1-PHENYL-3-(5-ARYL-2-FURYL)-PROPENONEN UND 1-PHENYL-3-(5-ARYL-2-THIENYL)-PROPENONEN Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197335063 |
0.322 |
|
| 1972 |
Das BP, Campbell JA, Samples FB, Wallace RA, Whisenant LK, Woodard RW, Boykin DW. Naphthothiophenes. 1. Alpha-(alkylaminomethyl)-4-naphtho(2,1-b) thiophenemethanols as antimalarials. Journal of Medicinal Chemistry. 15: 370-4. PMID 5019552 DOI: 10.1021/Jm00274A010 |
0.486 |
|
| 1972 |
DAS BP, CAMBELL JA, SAMPLES FB, WALLACE RA, WHISENANT LK, WOODARD RW, BOYKIN DW. ChemInform Abstract: NAPHTHOTHIOPHENE 1. MITT. ALPHA-(ALKYLAMINOMETHYL)-4-NAPHTHO(2,1-B)THIOPHENMETHANOLE ALS MALARIAMITTEL Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/Chin.197235280 |
0.534 |
|
| 1972 |
WOODARD RW, BALDZER K, BOYKIN DW. ChemInform Abstract: SYNTH. EINIGER 5-SUBSTITUIERTER 10,11-DIHYDRODIBENZO(B,F)AZEPINE Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/Chin.197222319 |
0.547 |
|
| 1971 |
Woodard RW, Baldzer K, Boykin DW. Synthesis of some 5-substituted 10,11-dihydrodibenz[b,f]azepines. Journal of Medicinal Chemistry. 14: 1131-2. PMID 4398900 |
0.531 |
|
| 1971 |
Turner AB, Lutz RE, Mcfarlane NS, Boykin DW. Solvent effects in nuclear magnetic resonance spectroscopy. II. Transmission of substituent effects by three-membered rings Journal of Organic Chemistry. 36: 1107-1112. DOI: 10.1021/Jo00807A022 |
0.51 |
|
| 1971 |
TURNER AB, LUTZ RE, MCFARLANE NS, BOYKIN DW. ChemInform Abstract: LOESUNGSMITTELEFFEKTE BEI NMR-SPEKTROSKOPISCHEN UNTERSUCHUNGEN 2. MITT. DIE UEBERTRAGUNG VON SUBSTITUENTENEINFLUESSEN DURCH DREIGLIEDRIGE RINGE Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197130083 |
0.534 |
|
| 1971 |
DAS BP, WOODARD RW, WHISENANT LK, WINECOFF WFI, BOYKIN DW. ChemInform Abstract: SYNTH. EINIGER SUBSTITUIERTER 10-AMINO-10,11-DIHYDRO-5H-DIBENZ(B,F)AZEPINE Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197102368 |
0.559 |
|
| 1970 |
Das BP, Woodard RW, Whisenant LK, Winecoff WF, Boykin DW. Synthesis of some substituted 10-amino-10,11-dihydro-5H-dibenz[b,f]azepines. Journal of Medicinal Chemistry. 13: 979-81. PMID 5458397 DOI: 10.1021/Jm00299A046 |
0.581 |
|
| 1970 |
Woodard RW, Boykin DW. Steric effects on the carbonyl stretching frequencies of alkyl styryl ketones Journal of the Chemical Society D: Chemical Communications. 628-629. DOI: 10.1039/C29700000628 |
0.505 |
|
| 1970 |
Hankins WM, Lutz RE, Anderson EL, Hankins MG, Boykin DW. Tetrasubstituted 2,5-hydrofuranols and their anomerism Journal of Organic Chemistry. 35: 2934-2938. DOI: 10.1021/Jo00834A018 |
0.522 |
|
| 1970 |
HANKINS WM, LUTZ RE, ANDERSON EL, HANKINS MG, BOYKIN DW. ChemInform Abstract: TETRASUBSTITUIERTE 2,5-HYDROFURANOLE UND IHRE ANOMERIE Chemischer Informationsdienst. Organische Chemie. 1: no-no. DOI: 10.1002/Chin.197047308 |
0.486 |
|
| 1968 |
Boykin DW, Patel AR, Lutz RE. Antimalarials. IV. A new synthesis of alpha-(2-pyridyl)-and alpha-(2-piperidyl)-2-aryl-4-quinolinemethanols. Journal of Medicinal Chemistry. 11: 273-7. PMID 5654217 DOI: 10.1021/Jm00308A019 |
0.489 |
|
| 1968 |
Tenney LP, Hankins WM, Lutz RE, Boykin DW. Oxidative furanizations of phenylated unsaturated ketones. Intermediate 5,5-diphenyl furanonium salts: Phenyl group migrations and reductions to 2,5-dihydrofurans Journal of Heterocyclic Chemistry. 5: 435-436. DOI: 10.1002/Jhet.5570050327 |
0.461 |
|
| 1967 |
Lutz RE, Boykin DW. Oxidations of tetraphenylpyrroles Journal of Organic Chemistry. 32: 1179-1183. DOI: 10.1021/Jo01279A072 |
0.457 |
|
| 1967 |
Boykin DW, Turner AB, Lutz RE. Solvent effects in N.M.R. spectroscopy. Determination of configurations of three-membered ring carbonyl compounds by benzene induced chemical shifts Tetrahedron Letters. 8: 817-822. DOI: 10.1016/S0040-4039(00)71569-3 |
0.507 |
|
| 1967 |
Boykin DW, Patel AR, Lutz RE, Burger A. Pyridyl ketones by addition of pyridyllithium to carboxylic acids. A new synthesis of α- (2-piperidyl)-2-aryl-4-quinolinemethanols Journal of Heterocyclic Chemistry. 4: 459-460. DOI: 10.1002/Jhet.5570040338 |
0.467 |
|
| 1966 |
Tenney LP, Boykin DW, Lutz RE. Novel photocyclization of a highly phenylated β,γ-unsaturated ketone to a cyclopropyl ketone, involving benzoyl group migration [19] Journal of the American Chemical Society. 88: 1835-1836. DOI: 10.1021/Ja00960A059 |
0.508 |
|
| 1964 |
Lutz RE, Bass RG, Boykin DW. Rearrangement of the Vinylog of Benzpinacol1-3 Journal of Organic Chemistry. 29: 3660-3664. DOI: 10.1021/Jo01035A057 |
0.513 |
|
| 1964 |
Boykin DW, Lutz RE. Phenylated dihydrofurans. Photo- and acid-catalyzed rearrangements and intermediacy in cyclopropyl ketone cleavage [39] Journal of the American Chemical Society. 86: 5046-5047. DOI: 10.1021/Ja01076A092 |
0.521 |
|
| 1964 |
Lutz RE, Bass RG, Boykin DW. Rearrangement of the vinylog of benzpinacol Journal of Organic Chemistry. 29: 3660-3664. |
0.456 |
|
| 1963 |
Lutz RE, Dale JI, Boykin DW. A novel phenyl group migration during pyrolysis and photolysis of bis-(2,3,5,5-tetraphenyl-2-dihydrofuranyl)-hydrazine [18] Journal of the American Chemical Society. 85: 2340-2341. DOI: 10.1021/Ja00898A046 |
0.522 |
|
| Show low-probability matches. |
