Frédéric Saudou, PhD - Publications

1999-2013 Inserm U1005 Institut Curie, Bures-sur-Yvette, Île-de-France, France 
 2013- Grenoble Institute of Neurosciences Université Grenoble Alpes, INSERM 
Huntington's disease, intracellular dynamics, axonal transport

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Kratter IH, Zahed H, Lau A, Tsvetkov AS, Daub AC, Weiberth KF, Gu X, Saudou F, Humbert S, Yang XW, Osmand A, Steffan JS, Masliah E, Finkbeiner S. Serine 421 regulates mutant huntingtin toxicity and clearance in mice. The Journal of Clinical Investigation. PMID 27525439 DOI: 10.1172/JCI80339  1
2015 El-Daher MT, Hangen E, Bruyère J, Poizat G, Al-Ramahi I, Pardo R, Bourg N, Souquere S, Mayet C, Pierron G, Lévêque-Fort S, Botas J, Humbert S, Saudou F. Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation. The Embo Journal. 34: 2255-71. PMID 26165689 DOI: 10.15252/embj.201490808  1
2014 Ochaba J, Lukacsovich T, Csikos G, Zheng S, Margulis J, Salazar L, Mao K, Lau AL, Yeung SY, Humbert S, Saudou F, Klionsky DJ, Finkbeiner S, Zeitlin SO, Marsh JL, et al. Potential function for the Huntingtin protein as a scaffold for selective autophagy. Proceedings of the National Academy of Sciences of the United States of America. 111: 16889-94. PMID 25385587 DOI: 10.1073/pnas.1420103111  1
2014 Drouet V, Ruiz M, Zala D, Feyeux M, Auregan G, Cambon K, Troquier L, Carpentier J, Aubert S, Merienne N, Bourgois-Rocha F, Hassig R, Rey M, Dufour N, Saudou F, et al. Allele-specific silencing of mutant huntingtin in rodent brain and human stem cells. Plos One. 9: e99341. PMID 24926995 DOI: 10.1371/journal.pone.0099341  1
2012 Roux JC, Zala D, Panayotis N, Borges-Correia A, Saudou F, Villard L. [Unexpected link between Huntington disease and Rett syndrome]. MéDecine Sciences : M/S. 28: 44-6. PMID 22289830 DOI: 10.1051/medsci/2012281016  1
2012 Roux JC, Zala D, Panayotis N, Borges-Correia A, Saudou F, Villard L. Modification of Mecp2 dosage alters axonal transport through the Huntingtin/Hap1 pathway. Neurobiology of Disease. 45: 786-95. PMID 22127389 DOI: 10.1016/j.nbd.2011.11.002  1
2011 Keryer G, Pineda JR, Liot G, Kim J, Dietrich P, Benstaali C, Smith K, Cordelières FP, Spassky N, Ferrante RJ, Dragatsis I, Saudou F. Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease. The Journal of Clinical Investigation. 121: 4372-82. PMID 21985783 DOI: 10.1172/JCI57552  1
2011 Marquer C, Devauges V, Cossec JC, Liot G, Lécart S, Saudou F, Duyckaerts C, Lévêque-Fort S, Potier MC. Local cholesterol increase triggers amyloid precursor protein-Bace1 clustering in lipid rafts and rapid endocytosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1295-305. PMID 21257714 DOI: 10.1096/fj.10-168633  1
2010 Godin JD, Colombo K, Molina-Calavita M, Keryer G, Zala D, Charrin BC, Dietrich P, Volvert ML, Guillemot F, Dragatsis I, Bellaiche Y, Saudou F, Nguyen L, Humbert S. Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis. Neuron. 67: 392-406. PMID 20696378 DOI: 10.1016/j.neuron.2010.06.027  1
2010 del Toro D, Xifró X, Pol A, Humbert S, Saudou F, Canals JM, Alberch J. Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington's disease. Journal of Neurochemistry. 115: 153-67. PMID 20663016 DOI: 10.1111/j.1471-4159.2010.06912.x  1
2010 Twelvetrees AE, Yuen EY, Arancibia-Carcamo IL, MacAskill AF, Rostaing P, Lumb MJ, Humbert S, Triller A, Saudou F, Yan Z, Kittler JT. Delivery of GABAARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin. Neuron. 65: 53-65. PMID 20152113 DOI: 10.1016/j.neuron.2009.12.007  1
2010 Nguyen L, Humbert S, Saudou F, Chariot A. Elongator - an emerging role in neurological disorders. Trends in Molecular Medicine. 16: 1-6. PMID 20036197 DOI: 10.1016/j.molmed.2009.11.002  1
2006 Borrell-Pagès M, Canals JM, Cordelières FP, Parker JA, Pineda JR, Grange G, Bryson EA, Guillermier M, Hirsch E, Hantraye P, Cheetham ME, Néri C, Alberch J, Brouillet E, Saudou F, et al. Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase. The Journal of Clinical Investigation. 116: 1410-24. PMID 16604191 DOI: 10.1172/JCI27607  1
2006 Pardo R, Colin E, Régulier E, Aebischer P, Déglon N, Humbert S, Saudou F. Inhibition of calcineurin by FK506 protects against polyglutamine-huntingtin toxicity through an increase of huntingtin phosphorylation at S421. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1635-45. PMID 16452687 DOI: 10.1523/JNEUROSCI.3706-05.2006  1
2006 Benchoua A, Trioulier Y, Zala D, Gaillard MC, Lefort N, Dufour N, Saudou F, Elalouf JM, Hirsch E, Hantraye P, Déglon N, Brouillet E. Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin. Molecular Biology of the Cell. 17: 1652-63. PMID 16452635 DOI: 10.1091/mbc.E05-07-0607  1
2005 Colin E, Régulier E, Perrin V, Dürr A, Brice A, Aebischer P, Déglon N, Humbert S, Saudou F. Akt is altered in an animal model of Huntington's disease and in patients. The European Journal of Neuroscience. 21: 1478-88. PMID 15845076 DOI: 10.1111/j.1460-9568.2005.03985.x  1
2005 Rangone H, Pardo R, Colin E, Girault JA, Saudou F, Humbert S. Phosphorylation of arfaptin 2 at Ser260 by Akt Inhibits PolyQ-huntingtin-induced toxicity by rescuing proteasome impairment. The Journal of Biological Chemistry. 280: 22021-8. PMID 15809304 DOI: 10.1074/jbc.M407528200  1
2004 Gauthier LR, Charrin BC, Borrell-Pagès M, Dompierre JP, Rangone H, Cordelières FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, Saudou F. Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell. 118: 127-38. PMID 15242649 DOI: 10.1016/j.cell.2004.06.018  1
2004 Rangone H, Poizat G, Troncoso J, Ross CA, MacDonald ME, Saudou F, Humbert S. The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin. The European Journal of Neuroscience. 19: 273-9. PMID 14725621 DOI: 10.1111/j.0953-816X.2003.03131.x  1
2003 Bizat N, Hermel JM, Humbert S, Jacquard C, Créminon C, Escartin C, Saudou F, Krajewski S, Hantraye P, Brouillet E. In vivo calpain/caspase cross-talk during 3-nitropropionic acid-induced striatal degeneration: implication of a calpain-mediated cleavage of active caspase-3. The Journal of Biological Chemistry. 278: 43245-53. PMID 12917435 DOI: 10.1074/jbc.M305057200  1
2003 Holbert S, Dedeoglu A, Humbert S, Saudou F, Ferrante RJ, Néri C. Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 2712-7. PMID 12604778 DOI: 10.1073/pnas.0437967100  1
2002 Humbert S, Bryson EA, Cordelières FP, Connors NC, Datta SR, Finkbeiner S, Greenberg ME, Saudou F. The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt. Developmental Cell. 2: 831-7. PMID 12062094 DOI: 10.1016/S1534-5807(02)00188-0  1
1998 Saudou F, Finkbeiner S, Devys D, Greenberg ME. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell. 95: 55-66. PMID 9778247 DOI: 10.1016/S0092-8674(00)81782-1  1
1998 Hiroi N, Marek GJ, Brown JR, Ye H, Saudou F, Vaidya VA, Duman RS, Greenberg ME, Nestler EJ. Essential role of the fosB gene in molecular, cellular, and behavioral actions of chronic electroconvulsive seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6952-62. PMID 9712664  1
1998 Brown JR, Nigh E, Lee RJ, Ye H, Thompson MA, Saudou F, Pestell RG, Greenberg ME. Fos family members induce cell cycle entry by activating cyclin D1. Molecular and Cellular Biology. 18: 5609-19. PMID 9710644  1
1998 Lucas JJ, Yamamoto A, Scearce-Levie K, Saudou F, Hen R. Absence of fenfluramine-induced anorexia and reduced c-Fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5537-44. PMID 9651234  1
1997 David G, Abbas N, Stevanin G, Dürr A, Yvert G, Cancel G, Weber C, Imbert G, Saudou F, Antoniou E, Drabkin H, Gemmill R, Giunti P, Benomar A, Wood N, et al. Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion. Nature Genetics. 17: 65-70. PMID 9288099 DOI: 10.1038/ng0997-65  1
1997 Cancel G, Dürr A, Didierjean O, Imbert G, Bürk K, Lezin A, Belal S, Benomar A, Abada-Bendib M, Vial C, Guimarães J, Chneiweiss H, Stevanin G, Yvert G, Abbas N, ... Saudou F, et al. Molecular and clinical correlations in spinocerebellar ataxia 2: a study of 32 families. Human Molecular Genetics. 6: 709-15. PMID 9158145  1
1996 Imbert G, Saudou F, Yvert G, Devys D, Trottier Y, Garnier JM, Weber C, Mandel JL, Cancel G, Abbas N, Dürr A, Didierjean O, Stevanin G, Agid Y, Brice A. Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats. Nature Genetics. 14: 285-91. PMID 8896557 DOI: 10.1038/ng1196-285  1
1996 Ramboz S, Saudou F, Amara DA, Belzung C, Segu L, Misslin R, Buhot MC, Hen R. 5-HT1B receptor knock out--behavioral consequences. Behavioural Brain Research. 73: 305-12. PMID 8788525 DOI: 10.1016/0166-4328(96)00119-2  1
1996 Ramboz S, Saudou F, Amara DA, Belzung C, Dierich A, LeMeur M, Segu L, Misslin R, Buhot MC, Hen R. Behavioral characterization of mice packing the 5-HT1B receptor. Nida Research Monograph. 161: 39-57. PMID 8784843  1
1994 Saudou F, Amara DA, Dierich A, LeMeur M, Ramboz S, Segu L, Buhot MC, Hen R. Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Science (New York, N.Y.). 265: 1875-8. PMID 8091214  1
1994 Saudou F, Hen R. 5-Hydroxytryptamine receptor subtypes in vertebrates and invertebrates. Neurochemistry International. 25: 503-32. PMID 7894328 DOI: 10.1016/0197-0186(94)90150-3  1
1994 Saudou F, Hen R. 5-Hydroxytryptamine receptor subtypes: molecular and functional diversity. Advances in Pharmacology (San Diego, Calif.). 30: 327-80. PMID 7833295 DOI: 10.1016/S1054-3589(08)60178-7  1
1992 Maroteaux L, Saudou F, Amlaiky N, Boschert U, Plassat JL, Hen R. Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers. Proceedings of the National Academy of Sciences of the United States of America. 89: 3020-4. PMID 1557407  1
1992 Saudou F, Boschert U, Amlaiky N, Plassat JL, Hen R. A family of Drosophila serotonin receptors with distinct intracellular signalling properties and expression patterns. The Embo Journal. 11: 7-17. PMID 1310937  1
1990 Saudou F, Amlaiky N, Plassat JL, Borrelli E, Hen R. Cloning and characterization of a Drosophila tyramine receptor. The Embo Journal. 9: 3611-7. PMID 2170118  1
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