Frédéric Saudou, PhD - Publications

Affiliations: 
1999-2013 Inserm U1005 Institut Curie, Bures-sur-Yvette, Île-de-France, France 
 2013- Grenoble Institute of Neurosciences Université Grenoble Alpes, INSERM 
Area:
Huntington's disease, intracellular dynamics, axonal transport
Website:
https://neurosciences.ujf-grenoble.fr/search/team-saudou-intracellular-dynamics-neurodegeneration?language=en

37/99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Kratter IH, Zahed H, Lau A, Tsvetkov AS, Daub AC, Weiberth KF, Gu X, Saudou F, Humbert S, Yang XW, Osmand A, Steffan JS, Masliah E, Finkbeiner S. Serine 421 regulates mutant huntingtin toxicity and clearance in mice. The Journal of Clinical Investigation. PMID 27525439 DOI: 10.1172/JCI80339  1
2015 El-Daher MT, Hangen E, Bruyère J, Poizat G, Al-Ramahi I, Pardo R, Bourg N, Souquere S, Mayet C, Pierron G, Lévêque-Fort S, Botas J, Humbert S, Saudou F. Huntingtin proteolysis releases non-polyQ fragments that cause toxicity through dynamin 1 dysregulation. The Embo Journal. 34: 2255-71. PMID 26165689 DOI: 10.15252/embj.201490808  1
2014 Ochaba J, Lukacsovich T, Csikos G, Zheng S, Margulis J, Salazar L, Mao K, Lau AL, Yeung SY, Humbert S, Saudou F, Klionsky DJ, Finkbeiner S, Zeitlin SO, Marsh JL, et al. Potential function for the Huntingtin protein as a scaffold for selective autophagy. Proceedings of the National Academy of Sciences of the United States of America. 111: 16889-94. PMID 25385587 DOI: 10.1073/pnas.1420103111  1
2014 Drouet V, Ruiz M, Zala D, Feyeux M, Auregan G, Cambon K, Troquier L, Carpentier J, Aubert S, Merienne N, Bourgois-Rocha F, Hassig R, Rey M, Dufour N, Saudou F, et al. Allele-specific silencing of mutant huntingtin in rodent brain and human stem cells. Plos One. 9: e99341. PMID 24926995 DOI: 10.1371/journal.pone.0099341  1
2012 Roux JC, Zala D, Panayotis N, Borges-Correia A, Saudou F, Villard L. [Unexpected link between Huntington disease and Rett syndrome]. MéDecine Sciences : M/S. 28: 44-6. PMID 22289830 DOI: 10.1051/medsci/2012281016  1
2012 Roux JC, Zala D, Panayotis N, Borges-Correia A, Saudou F, Villard L. Modification of Mecp2 dosage alters axonal transport through the Huntingtin/Hap1 pathway. Neurobiology of Disease. 45: 786-95. PMID 22127389 DOI: 10.1016/j.nbd.2011.11.002  1
2011 Keryer G, Pineda JR, Liot G, Kim J, Dietrich P, Benstaali C, Smith K, Cordelières FP, Spassky N, Ferrante RJ, Dragatsis I, Saudou F. Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease. The Journal of Clinical Investigation. 121: 4372-82. PMID 21985783 DOI: 10.1172/JCI57552  1
2011 Marquer C, Devauges V, Cossec JC, Liot G, Lécart S, Saudou F, Duyckaerts C, Lévêque-Fort S, Potier MC. Local cholesterol increase triggers amyloid precursor protein-Bace1 clustering in lipid rafts and rapid endocytosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1295-305. PMID 21257714 DOI: 10.1096/fj.10-168633  1
2010 Godin JD, Colombo K, Molina-Calavita M, Keryer G, Zala D, Charrin BC, Dietrich P, Volvert ML, Guillemot F, Dragatsis I, Bellaiche Y, Saudou F, Nguyen L, Humbert S. Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis. Neuron. 67: 392-406. PMID 20696378 DOI: 10.1016/j.neuron.2010.06.027  1
2010 del Toro D, Xifró X, Pol A, Humbert S, Saudou F, Canals JM, Alberch J. Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington's disease. Journal of Neurochemistry. 115: 153-67. PMID 20663016 DOI: 10.1111/j.1471-4159.2010.06912.x  1
2010 Twelvetrees AE, Yuen EY, Arancibia-Carcamo IL, MacAskill AF, Rostaing P, Lumb MJ, Humbert S, Triller A, Saudou F, Yan Z, Kittler JT. Delivery of GABAARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin. Neuron. 65: 53-65. PMID 20152113 DOI: 10.1016/j.neuron.2009.12.007  1
2010 Nguyen L, Humbert S, Saudou F, Chariot A. Elongator - an emerging role in neurological disorders. Trends in Molecular Medicine. 16: 1-6. PMID 20036197 DOI: 10.1016/j.molmed.2009.11.002  1
2006 Borrell-Pagès M, Canals JM, Cordelières FP, Parker JA, Pineda JR, Grange G, Bryson EA, Guillermier M, Hirsch E, Hantraye P, Cheetham ME, Néri C, Alberch J, Brouillet E, Saudou F, et al. Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase. The Journal of Clinical Investigation. 116: 1410-24. PMID 16604191 DOI: 10.1172/JCI27607  1
2006 Pardo R, Colin E, Régulier E, Aebischer P, Déglon N, Humbert S, Saudou F. Inhibition of calcineurin by FK506 protects against polyglutamine-huntingtin toxicity through an increase of huntingtin phosphorylation at S421. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1635-45. PMID 16452687 DOI: 10.1523/JNEUROSCI.3706-05.2006  1
2006 Benchoua A, Trioulier Y, Zala D, Gaillard MC, Lefort N, Dufour N, Saudou F, Elalouf JM, Hirsch E, Hantraye P, Déglon N, Brouillet E. Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin. Molecular Biology of the Cell. 17: 1652-63. PMID 16452635 DOI: 10.1091/mbc.E05-07-0607  1
2005 Colin E, Régulier E, Perrin V, Dürr A, Brice A, Aebischer P, Déglon N, Humbert S, Saudou F. Akt is altered in an animal model of Huntington's disease and in patients. The European Journal of Neuroscience. 21: 1478-88. PMID 15845076 DOI: 10.1111/j.1460-9568.2005.03985.x  1
2005 Rangone H, Pardo R, Colin E, Girault JA, Saudou F, Humbert S. Phosphorylation of arfaptin 2 at Ser260 by Akt Inhibits PolyQ-huntingtin-induced toxicity by rescuing proteasome impairment. The Journal of Biological Chemistry. 280: 22021-8. PMID 15809304 DOI: 10.1074/jbc.M407528200  1
2004 Gauthier LR, Charrin BC, Borrell-Pagès M, Dompierre JP, Rangone H, Cordelières FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, Saudou F. Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell. 118: 127-38. PMID 15242649 DOI: 10.1016/j.cell.2004.06.018  1
2004 Rangone H, Poizat G, Troncoso J, Ross CA, MacDonald ME, Saudou F, Humbert S. The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin. The European Journal of Neuroscience. 19: 273-9. PMID 14725621 DOI: 10.1111/j.0953-816X.2003.03131.x  1
2003 Bizat N, Hermel JM, Humbert S, Jacquard C, Créminon C, Escartin C, Saudou F, Krajewski S, Hantraye P, Brouillet E. In vivo calpain/caspase cross-talk during 3-nitropropionic acid-induced striatal degeneration: implication of a calpain-mediated cleavage of active caspase-3. The Journal of Biological Chemistry. 278: 43245-53. PMID 12917435 DOI: 10.1074/jbc.M305057200  1
2003 Holbert S, Dedeoglu A, Humbert S, Saudou F, Ferrante RJ, Néri C. Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 2712-7. PMID 12604778 DOI: 10.1073/pnas.0437967100  1
2002 Humbert S, Bryson EA, Cordelières FP, Connors NC, Datta SR, Finkbeiner S, Greenberg ME, Saudou F. The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt. Developmental Cell. 2: 831-7. PMID 12062094 DOI: 10.1016/S1534-5807(02)00188-0  1
1998 Saudou F, Finkbeiner S, Devys D, Greenberg ME. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell. 95: 55-66. PMID 9778247 DOI: 10.1016/S0092-8674(00)81782-1  1
1998 Hiroi N, Marek GJ, Brown JR, Ye H, Saudou F, Vaidya VA, Duman RS, Greenberg ME, Nestler EJ. Essential role of the fosB gene in molecular, cellular, and behavioral actions of chronic electroconvulsive seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6952-62. PMID 9712664  1
1998 Brown JR, Nigh E, Lee RJ, Ye H, Thompson MA, Saudou F, Pestell RG, Greenberg ME. Fos family members induce cell cycle entry by activating cyclin D1. Molecular and Cellular Biology. 18: 5609-19. PMID 9710644  1
1998 Lucas JJ, Yamamoto A, Scearce-Levie K, Saudou F, Hen R. Absence of fenfluramine-induced anorexia and reduced c-Fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5537-44. PMID 9651234  1
1997 David G, Abbas N, Stevanin G, Dürr A, Yvert G, Cancel G, Weber C, Imbert G, Saudou F, Antoniou E, Drabkin H, Gemmill R, Giunti P, Benomar A, Wood N, et al. Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion. Nature Genetics. 17: 65-70. PMID 9288099 DOI: 10.1038/ng0997-65  1
1997 Cancel G, Dürr A, Didierjean O, Imbert G, Bürk K, Lezin A, Belal S, Benomar A, Abada-Bendib M, Vial C, Guimarães J, Chneiweiss H, Stevanin G, Yvert G, Abbas N, ... Saudou F, et al. Molecular and clinical correlations in spinocerebellar ataxia 2: a study of 32 families. Human Molecular Genetics. 6: 709-15. PMID 9158145  1
1996 Imbert G, Saudou F, Yvert G, Devys D, Trottier Y, Garnier JM, Weber C, Mandel JL, Cancel G, Abbas N, Dürr A, Didierjean O, Stevanin G, Agid Y, Brice A. Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats. Nature Genetics. 14: 285-91. PMID 8896557 DOI: 10.1038/ng1196-285  1
1996 Ramboz S, Saudou F, Amara DA, Belzung C, Segu L, Misslin R, Buhot MC, Hen R. 5-HT1B receptor knock out--behavioral consequences. Behavioural Brain Research. 73: 305-12. PMID 8788525 DOI: 10.1016/0166-4328(96)00119-2  1
1996 Ramboz S, Saudou F, Amara DA, Belzung C, Dierich A, LeMeur M, Segu L, Misslin R, Buhot MC, Hen R. Behavioral characterization of mice packing the 5-HT1B receptor. Nida Research Monograph. 161: 39-57. PMID 8784843  1
1994 Saudou F, Amara DA, Dierich A, LeMeur M, Ramboz S, Segu L, Buhot MC, Hen R. Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Science (New York, N.Y.). 265: 1875-8. PMID 8091214  1
1994 Saudou F, Hen R. 5-Hydroxytryptamine receptor subtypes in vertebrates and invertebrates. Neurochemistry International. 25: 503-32. PMID 7894328 DOI: 10.1016/0197-0186(94)90150-3  1
1994 Saudou F, Hen R. 5-Hydroxytryptamine receptor subtypes: molecular and functional diversity. Advances in Pharmacology (San Diego, Calif.). 30: 327-80. PMID 7833295 DOI: 10.1016/S1054-3589(08)60178-7  1
1992 Maroteaux L, Saudou F, Amlaiky N, Boschert U, Plassat JL, Hen R. Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers. Proceedings of the National Academy of Sciences of the United States of America. 89: 3020-4. PMID 1557407  1
1992 Saudou F, Boschert U, Amlaiky N, Plassat JL, Hen R. A family of Drosophila serotonin receptors with distinct intracellular signalling properties and expression patterns. The Embo Journal. 11: 7-17. PMID 1310937  1
1990 Saudou F, Amlaiky N, Plassat JL, Borrelli E, Hen R. Cloning and characterization of a Drosophila tyramine receptor. The Embo Journal. 9: 3611-7. PMID 2170118  1
Low-probability matches
2011 Miller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, ... ... Saudou F, et al. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nature Chemical Biology. 7: 925-34. PMID 22037470 DOI: 10.1038/nchembio.694  0.24
1997 Gourfinkel-An I, Cancel G, Trottier Y, Devys D, Tora L, Lutz Y, Imbert G, Saudou F, Stevanin G, Agid Y, Brice A, Mandel JL, Hirsch EC. Differential distribution of the normal and mutated forms of huntingtin in the human brain. Annals of Neurology. 42: 712-9. PMID 9392570 DOI: 10.1002/ana.410420507  0.24
1996 Saudou F, Devys D, Trottier Y, Imbert G, Stoeckel ME, Brice A, Mandel JL. Polyglutamine expansions and neurodegenerative diseases. Cold Spring Harbor Symposia On Quantitative Biology. 61: 639-47. PMID 9246490  0.24
1995 Trottier Y, Devys D, Imbert G, Saudou F, An I, Lutz Y, Weber C, Agid Y, Hirsch EC, Mandel JL. Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form. Nature Genetics. 10: 104-10. PMID 7647777 DOI: 10.1038/ng0595-104  0.24
1996 Stevanin G, Trottier Y, Cancel G, Dürr A, David G, Didierjean O, Bürk K, Imbert G, Saudou F, Abada-Bendib M, Gourfinkel-An I, Benomar A, Abbas N, Klockgether T, Grid D, et al. Screening for proteins with polyglutamine expansions in autosomal dominant cerebellar ataxias. Human Molecular Genetics. 5: 1887-92. PMID 8968739  0.2
2021 Lenoir S, Genoux A, Agasse F, Saudou F, Humbert S. Recreating mouse cortico-hippocampal neuronal circuit in microfluidic devices to study BDNF axonal transport upon glucocorticoid treatment. Star Protocols. 2: 100382. PMID 33748784 DOI: 10.1016/j.xpro.2021.100382  0.12
2020 Agasse F, Mendez-David I, Christaller W, Carpentier R, Braz BY, David DJ, Saudou F, Humbert S. Chronic Corticosterone Elevation Suppresses Adult Hippocampal Neurogenesis by Hyperphosphorylating Huntingtin. Cell Reports. 32: 107865. PMID 32640230 DOI: 10.1016/j.celrep.2020.107865  0.12
2020 Bruyère J, Abada YS, Vitet HM, Fontaine G, Deloulme JC, Cès A, Denarier E, Pernet-Gallay K, Andrieux A, Humbert S, Potier MC, Delatour B, Saudou F. Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of Huntingtin. Elife. 9. PMID 32452382 DOI: 10.7554/eLife.56371  0.12
2018 Galvan L, Francelle L, Gaillard MC, de Longprez L, Carrillo-de Sauvage MA, Liot G, Cambon K, Stimmer L, Luccantoni S, Flament J, Valette J, de Chaldée M, Auregan G, Guillermier M, Joséphine C, ... ... Saudou F, et al. The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin. Brain : a Journal of Neurology. PMID 29534157 DOI: 10.1093/brain/awy057  0.12
2016 Saudou F, Humbert S. The Biology of Huntingtin. Neuron. 89: 910-26. PMID 26938440 DOI: 10.1016/j.neuron.2016.02.003  0.12
2015 Naia L, Ferreira IL, Cunha-Oliveira T, Duarte AI, Ribeiro M, Rosenstock TR, Laço MN, Ribeiro MJ, Oliveira CR, Saudou F, Humbert S, Rego AC. Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington's Disease human lymphoblasts. Molecular Neurobiology. 51: 331-48. PMID 24841383 DOI: 10.1007/s12035-014-8735-4  0.12
2014 Pla P, Orvoen S, Saudou F, David DJ, Humbert S. Mood disorders in Huntington's disease: from behavior to cellular and molecular mechanisms. Frontiers in Behavioral Neuroscience. 8: 135. PMID 24795586 DOI: 10.3389/fnbeh.2014.00135  0.12
2014 Lopes C, Ribeiro M, Duarte AI, Humbert S, Saudou F, Pereira de Almeida L, Hayden M, Rego AC. IGF-1 intranasal administration rescues Huntington's disease phenotypes in YAC128 mice. Molecular Neurobiology. 49: 1126-42. PMID 24347322 DOI: 10.1007/s12035-013-8585-5  0.12
2013 Pla P, Orvoen S, Benstaali C, Dodier S, Gardier AM, David DJ, Humbert S, Saudou F. Huntingtin acts non cell-autonomously on hippocampal neurogenesis and controls anxiety-related behaviors in adult mouse. Plos One. 8: e73902. PMID 24019939 DOI: 10.1371/journal.pone.0073902  0.12
2013 Ben M'Barek K, Pla P, Orvoen S, Benstaali C, Godin JD, Gardier AM, Saudou F, David DJ, Humbert S. Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 8608-20. PMID 23678106 DOI: 10.1523/JNEUROSCI.5110-12.2013  0.12
2013 Zala D, Hinckelmann MV, Yu H, Lyra da Cunha MM, Liot G, Cordelières FP, Marco S, Saudou F. Vesicular glycolysis provides on-board energy for fast axonal transport. Cell. 152: 479-91. PMID 23374344 DOI: 10.1016/j.cell.2012.12.029  0.12
2010 Pardo R, Molina-Calavita M, Poizat G, Keryer G, Humbert S, Saudou F. pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking. Molecular Brain. 3: 17. PMID 20515468 DOI: 10.1186/1756-6606-3-17  0.12
2009 Pineda JR, Pardo R, Zala D, Yu H, Humbert S, Saudou F. Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease. Molecular Brain. 2: 33. PMID 19860865 DOI: 10.1186/1756-6606-2-33  0.12
2008 Zala D, Colin E, Rangone H, Liot G, Humbert S, Saudou F. Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons. Human Molecular Genetics. 17: 3837-46. PMID 18772195 DOI: 10.1093/hmg/ddn281  0.12
2008 Saudou F, Humbert S. The biology of Huntington's disease. Handbook of Clinical Neurology. 89: 619-29. PMID 18631783 DOI: 10.1016/S0072-9752(07)01257-2  0.12
2008 Colin E, Zala D, Liot G, Rangone H, Borrell-Pagès M, Li XJ, Saudou F, Humbert S. Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons. The Embo Journal. 27: 2124-34. PMID 18615096 DOI: 10.1038/emboj.2008.133  0.12
2007 Anne SL, Saudou F, Humbert S. Phosphorylation of huntingtin by cyclin-dependent kinase 5 is induced by DNA damage and regulates wild-type and mutant huntingtin toxicity in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7318-28. PMID 17611284 DOI: 10.1523/JNEUROSCI.1831-07.2007  0.12
2007 Dompierre JP, Godin JD, Charrin BC, Cordelières FP, King SJ, Humbert S, Saudou F. Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3571-83. PMID 17392473 DOI: 10.1523/JNEUROSCI.0037-07.2007  0.12
2006 Saudou F, Humbert S. [Cysteamine restores intracellular dynamics and BDNF secretion in Huntington's disease]. MéDecine Sciences : M/S. 22: 906-8. PMID 17101082 DOI: 10.1051/medsci/20062211906  0.12
2006 Humbert S, Saudou F. The ataxia-ome: connecting disease proteins of the cerebellum. Cell. 125: 645-7. PMID 16713557 DOI: 10.1016/j.cell.2006.05.007  0.12
2005 Humbert S, Saudou F. [Huntington's disease: intracellular signaling pathways and neuronal death]. Journal De La SociéTé De Biologie. 199: 247-51. PMID 16471265 DOI: 10.1051/jbio:2005026  0.12
2005 Charrin BC, Saudou F, Humbert S. Axonal transport failure in neurodegenerative disorders: the case of Huntington's disease. Pathologie-Biologie. 53: 189-92. PMID 15850950 DOI: 10.1016/j.patbio.2004.12.008  0.12
2004 Humbert S, Saudou F. [Stimulation of BDNF transport by huntingtin]. MéDecine Sciences : M/S. 20: 952-4. PMID 15525484 DOI: 10.1051/medsci/20042011952  0.12
2002 Humbert S, Saudou F. Toward cell specificity in SCA1. Neuron. 34: 669-70. PMID 12062012  0.12
2012 Orvoen S, Pla P, Gardier AM, Saudou F, David DJ. Huntington's disease knock-in male mice show specific anxiety-like behaviour and altered neuronal maturation. Neuroscience Letters. 507: 127-32. PMID 22178857 DOI: 10.1016/j.neulet.2011.11.063  0.08
1995 Trottier Y, Lutz Y, Stevanin G, Imbert G, Devys D, Cancel G, Saudou F, Weber C, David G, Tora L. Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias. Nature. 378: 403-6. PMID 7477379 DOI: 10.1038/378403a0  0.08
2019 Even A, Morelli G, Broix L, Scaramuzzino C, Turchetto S, Gladwyn-Ng I, Le Bail R, Shilian M, Freeman S, Magiera MM, Jijumon AS, Krusy N, Malgrange B, Brone B, Dietrich P, ... ... Saudou F, et al. ATAT1-enriched vesicles promote microtubule acetylation via axonal transport. Science Advances. 5: eaax2705. PMID 31897425 DOI: 10.1126/sciadv.aax2705  0.04
2017 Khrimian L, Obri A, Ramos-Brossier M, Rousseaud A, Moriceau S, Nicot AS, Mera P, Kosmidis S, Karnavas T, Saudou F, Gao XB, Oury F, Kandel E, Karsenty G. Gpr158 mediates osteocalcin's regulation of cognition. The Journal of Experimental Medicine. PMID 28851741 DOI: 10.1084/jem.20171320  0.04
2009 Fjorback AW, Pla P, Müller HK, Wiborg O, Saudou F, Nyengaard JR. Serotonin transporter oligomerization documented in RN46A cells and neurons by sensitized acceptor emission FRET and fluorescence lifetime imaging microscopy. Biochemical and Biophysical Research Communications. 380: 724-8. PMID 19338744 DOI: 10.1016/j.bbrc.2009.01.128  0.04
1996 Imbert G, Saudou F, Yvert G, Mandel J, Cancel G, Brice A. Dernière heure : Maladies neurodégénératives par expansion de polyglutamines : le sixième gène cloné (SCA2) MéDecine/Sciences. 12: 1463. DOI: 10.4267/10608/700  0.04
2021 Fokin AI, David V, Oguievetskaia K, Derivery E, Stone CE, Cao L, Rocques N, Molinie N, Henriot V, Aumont-Nicaise M, Hinckelmann MV, Saudou F, Le Clainche C, Carter AP, Romet-Lemonne G, et al. The Arp1/11 minifilament of dynactin primes the endosomal Arp2/3 complex. Science Advances. 7. PMID 33523880 DOI: 10.1126/sciadv.abd5956  0.01
2020 Cunnane SC, Trushina E, Morland C, Prigione A, Casadesus G, Andrews ZB, Beal MF, Bergersen LH, Brinton RD, de la Monte S, Eckert A, Harvey J, Jeggo R, Jhamandas JH, Kann O, ... ... Saudou F, et al. Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing. Nature Reviews. Drug Discovery. PMID 32709961 DOI: 10.1038/s41573-020-0072-x  0.01
2020 Asselin L, Rivera Alvarez J, Heide S, Bonnet CS, Tilly P, Vitet H, Weber C, Bacino CA, Baranaño K, Chassevent A, Dameron A, Faivre L, Hanchard NA, Mahida S, McWalter K, ... ... Saudou F, et al. Mutations in the KIF21B kinesin gene cause neurodevelopmental disorders through imbalanced canonical motor activity. Nature Communications. 11: 2441. PMID 32415109 DOI: 10.1038/s41467-020-16294-6  0.01
2020 Vitet H, Brandt V, Saudou F. Traffic signaling: new functions of huntingtin and axonal transport in neurological disease. Current Opinion in Neurobiology. 63: 122-130. PMID 32408142 DOI: 10.1016/j.conb.2020.04.001  0.01
2020 Ehinger Y, Bruyère J, Panayotis N, Abada YS, Borloz E, Matagne V, Scaramuzzino C, Vitet H, Delatour B, Saidi L, Villard L, Saudou F, Roux JC. Huntingtin phosphorylation governs BDNF homeostasis and improves the phenotype of Mecp2 knockout mice. Embo Molecular Medicine. e10889. PMID 31913581 DOI: 10.15252/emmm.201910889  0.01
2019 Kacher R, Lamazière A, Heck N, Kappes V, Mounier C, Despres G, Dembitskaya Y, Perrin E, Christaller W, Sasidharan Nair S, Messent V, Cartier N, Vanhoutte P, Venance L, Saudou F, et al. CYP46A1 gene therapy deciphers the role of brain cholesterol metabolism in Huntington's disease. Brain : a Journal of Neurology. PMID 31286142 DOI: 10.1093/brain/awz174  0.01
2018 Zhang H, Zhang C, Vincent J, Zala D, Benstaali C, Sainlos M, Grillo-Bosch D, Daburon S, Coussen F, Cho Y, David DJ, Saudou F, Humeau Y, Choquet D. Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington's disease models. Nature Communications. 9: 4272. PMID 30323233 DOI: 10.1038/s41467-018-06675-3  0.01
2018 Moutaux E, Charlot B, Genoux A, Saudou F, Cazorla M. An integrated microfluidic/microelectrode array for the study of activity-dependent intracellular dynamics in neuronal networks. Lab On a Chip. PMID 30289147 DOI: 10.1039/c8lc00694f  0.01
2018 Moutaux E, Christaller W, Scaramuzzino C, Genoux A, Charlot B, Cazorla M, Saudou F. Neuronal network maturation differently affects secretory vesicles and mitochondria transport in axons. Scientific Reports. 8: 13429. PMID 30194421 DOI: 10.1038/s41598-018-31759-x  0.01
2018 Fino E, Vandecasteele M, Perez S, Saudou F, Venance L. Region-specific and state-dependent action of striatal GABAergic interneurons. Nature Communications. 9: 3339. PMID 30131490 DOI: 10.1038/s41467-018-05847-5  0.01
2018 Virlogeux A, Moutaux E, Christaller W, Genoux A, Bruyère J, Fino E, Charlot B, Cazorla M, Saudou F. Reconstituting Corticostriatal Network on-a-Chip Reveals the Contribution of the Presynaptic Compartment to Huntington's Disease. Cell Reports. 22: 110-122. PMID 29298414 DOI: 10.1016/j.celrep.2017.12.013  0.01
2017 Verny C, Bachoud-Lévi AC, Durr A, Goizet C, Azulay JP, Simonin C, Tranchant C, Calvas F, Krystkowiak P, Charles P, Youssov K, Scherer C, Prundean A, Olivier A, Reynier P, ... Saudou F, et al. A randomized, double-blind, placebo-controlled trial evaluating cysteamine in Huntington's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 28436572 DOI: 10.1002/mds.27010  0.01
2016 Hinckelmann MV, Virlogeux A, Niehage C, Poujol C, Choquet D, Hoflack B, Zala D, Saudou F. Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport. Nature Communications. 7: 13233. PMID 27775035 DOI: 10.1038/ncomms13233  0.01
2016 Virlogeux A, Cazorla M, Bruyère J, Christaller W, Genoux A, Charlot B, Saudou F. B41 HD on chip : reconstituting the cortico-striatal network on microfluidics to study intracellular trafficking and synaptic transmission Journal of Neurology, Neurosurgery & Psychiatry. 87: A23.3-A24. DOI: 10.1136/jnnp-2016-314597.72  0.01
2016 Saudou F. S.01.01 Autobahns in the brain: axonal transport and its disruption in neurological disorders European Neuropsychopharmacology. 26: S1-S2. DOI: 10.1016/S0924-977X(16)70002-2  0.01
2014 Marquer C, Laine J, Dauphinot L, Hanbouch L, Lemercier-Neuillet C, Pierrot N, Bossers K, Le M, Corlier F, Benstaali C, Saudou F, Thinakaran G, Cartier N, Octave JN, Duyckaerts C, et al. Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer's disease early phenotypes. Molecular Neurodegeneration. 9: 60. PMID 25524049 DOI: 10.1186/1750-1326-9-60  0.01
2013 Hinckelmann MV, Zala D, Saudou F. Releasing the brake: restoring fast axonal transport in neurodegenerative disorders. Trends in Cell Biology. 23: 634-43. PMID 24091156 DOI: 10.1016/j.tcb.2013.08.007  0.01
2013 Liot G, Zala D, Pla P, Mottet G, Piel M, Saudou F. Mutant Huntingtin alters retrograde transport of TrkB receptors in striatal dendrites. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6298-309. PMID 23575829 DOI: 10.1523/JNEUROSCI.2033-12.2013  0.01
2013 Zala D, Hinckelmann MV, Saudou F. Huntingtin's function in axonal transport is conserved in Drosophila melanogaster. Plos One. 8: e60162. PMID 23555909 DOI: 10.1371/journal.pone.0060162  0.01
2013 Saudou F, Zala D, Pla P, Hinckelmann M, Liot G. S.04.03 BDNF/TrkB signaling, axonal and dendritic transport and neurodegeneration in Huntington's disease European Neuropsychopharmacology. 23: S116. DOI: 10.1016/S0924-977X(13)70136-6  0.01
2012 Saudou F. A "so cilia" network: cilia proteins start "social" networking. The Journal of Clinical Investigation. 122: 1198-202. PMID 22446182 DOI: 10.1172/JCI62971  0.01
2012 Ben M'Barek K, Orvoen S, Pla P, Benstaali C, Godin J, Gardier A, Saudou F, David D, Humbert S. B14 Huntingtin mediates anxiety/depression-related behaviours in mouse through BDNF transport and hippocampal neurogenesis Journal of Neurology, Neurosurgery & Psychiatry. 83: A10.1-A10. DOI: 10.1136/jnnp-2012-303524.30  0.01
2008 Roze E, Saudou F, Caboche J. Pathophysiology of Huntington's disease: from huntingtin functions to potential treatments. Current Opinion in Neurology. 21: 497-503. PMID 18607213 DOI: 10.1097/WCO.0b013e328304b692  0.01
2006 Borrell-Pagès M, Zala D, Humbert S, Saudou F. Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies. Cellular and Molecular Life Sciences : Cmls. 63: 2642-60. PMID 17041811 DOI: 10.1007/s00018-006-6242-0  0.01
2004 Rangone H, Humbert S, Saudou F. Huntington's disease: how does huntingtin, an anti-apoptotic protein, become toxic? Pathologie-Biologie. 52: 338-42. PMID 15261377 DOI: 10.1016/J.PATBIO.2003.06.004  0.01
2003 Humbert S, Saudou F. Huntingtin phosphorylation and signaling pathways that regulate toxicity in Huntington's disease Clinical Neuroscience Research. 3: 149-155. DOI: 10.1016/S1566-2772(03)00057-4  0.01
1998 Hiroi N, Marek GJ, Brown JR, Ye H, Saudou F, Vaidya VA, Duman RS, Greenberg ME, Nestler EJ. Essential Role of thefosB Gene in Molecular, Cellular, and Behavioral Actions of Chronic Electroconvulsive Seizures The Journal of Neuroscience. 18: 6952-6962. DOI: 10.1523/JNEUROSCI.18-17-06952.1998  0.01
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