Ira Mellman - Publications

Affiliations: 
Yale, Genetech 
Area:
Membrane transport in cells
Website:
http://www.gene.com/scientists/our-scientists/ira-mellman

219 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Mellman I, Chen DS, Powles T, Turley SJ. The cancer-immunity cycle: Indication, genotype, and immunotype. Immunity. 56: 2188-2205. PMID 37820582 DOI: 10.1016/j.immuni.2023.09.011  0.361
2022 Ritter AT, Shtengel G, Xu CS, Weigel A, Hoffman DP, Freeman M, Iyer N, Alivodej N, Ackerman D, Voskoboinik I, Trapani J, Hess HF, Mellman I. ESCRT-mediated membrane repair protects tumor-derived cells against T cell attack. Science (New York, N.Y.). 376: 377-382. PMID 35446649 DOI: 10.1126/science.abl3855  0.303
2020 Vormehr M, Lehar S, Kranz LM, Tahtinen S, Oei Y, Javinal V, Delamarre L, Walzer KC, Diken M, Kreiter S, Mellman I, Sahin U, Schartner JM, Türeci Ö. Dexamethasone premedication suppresses vaccine-induced immune responses against cancer. Oncoimmunology. 9: 1758004. PMID 32923115 DOI: 10.1080/2162402X.2020.1758004  0.336
2020 Wu TD, Madireddi S, de Almeida PE, Banchereau R, Chen YJ, Chitre AS, Chiang EY, Iftikhar H, O'Gorman WE, Au-Yeung A, Takahashi C, Goldstein LD, Poon C, Keerthivasan S, de Almeida Nagata DE, ... ... Mellman I, et al. Peripheral T cell expansion predicts tumour infiltration and clinical response. Nature. PMID 32103181 DOI: 10.1038/S41586-020-2056-8  0.335
2019 Brand A, Diener N, Zahner SP, Tripp C, Backer RA, Karram K, Jiang A, Mellman I, Stoitzner P, Clausen BE. E-cadherin is dispensable to maintain Langerhans cells in the epidermis. The Journal of Investigative Dermatology. PMID 31260672 DOI: 10.1016/J.Jid.2019.06.132  0.319
2019 Xiong H, Mittman S, Rodriguez R, Pacheco-Sanchez P, Moskalenko M, Yang Y, Elstrott J, Ritter AT, Müller S, Nickles D, Arenzana TL, Capietto AH, Delamarre L, Modrusan Z, Rutz S, ... Mellman I, et al. Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8 T Cells in Murine Syngeneic Tumor Models. Cancer Immunology Research. PMID 31064777 DOI: 10.1158/2326-6066.Cir-18-0750  0.35
2018 Moussion C, Mellman I. The Dendritic Cell Strikes Back. Immunity. 49: 997-999. PMID 30566889 DOI: 10.1016/J.Immuni.2018.12.007  0.365
2018 Kowanetz M, Zou W, Gettinger SN, Koeppen H, Kockx M, Schmid P, Kadel EE, Wistuba I, Chaft J, Rizvi NA, Spigel DR, Spira A, Hirsch FR, Cohen V, Smith D, ... ... Mellman I, et al. Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1). Proceedings of the National Academy of Sciences of the United States of America. PMID 30297397 DOI: 10.1073/Pnas.1802166115  0.409
2018 Hernandez S, Qing J, Thibodeau RH, Du X, Park S, Lee HM, Xu M, Oh S, Navarro A, Roose-Girma M, Newman RJ, Warming S, Nannini M, Sampath D, Kim JM, ... ... Mellman I, et al. The Kinase Activity of Hematopoietic Progenitor Kinase 1 Is Essential for the Regulation of T Cell Function. Cell Reports. 25: 80-94. PMID 30282040 DOI: 10.1016/J.Celrep.2018.09.012  0.335
2018 Mariathasan S, Turley SJ, Nickles D, Castiglioni A, Yuen K, Wang Y, Kadel Iii EE, Koeppen H, Astarita JL, Cubas R, Jhunjhunwala S, Banchereau R, Yang Y, Guan Y, Chalouni C, ... ... Mellman I, et al. TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells. Nature. PMID 29443960 DOI: 10.1038/Nature25501  0.434
2018 Mariathasan S, Turley SJ, Nickles D, Castiglioni A, Yuen K, Wang Y, Kadel EE, Koeppen H, Astarita JL, Cubas R, Jhunjhunwala S, Yang Y, Şenbabaoğlu Y, Mellman I, Chen DS, et al. Abstract 2979: A balance of genomic instability, tumor-immune contexture and TGF-β signaling contributing to exclusion of T cells governs response to PD-L1 checkpoint blockade Cancer Research. 78: 2979-2979. DOI: 10.1158/1538-7445.Am2018-2979  0.433
2017 Baharom F, Thomas OS, Lepzien R, Mellman I, Chalouni C, Smed-Sörensen A. Visualization of early influenza A virus trafficking in human dendritic cells using STED microscopy. Plos One. 12: e0177920. PMID 28591131 DOI: 10.1371/Journal.Pone.0177920  0.354
2017 Vander Lugt B, Riddell J, Khan AA, Hackney JA, Lesch J, DeVoss J, Weirauch MT, Singh H, Mellman I. Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation. The Journal of Cell Biology. PMID 28130292 DOI: 10.1083/Jcb.201512012  0.379
2017 Chen DS, Mellman I. Elements of cancer immunity and the cancer-immune set point. Nature. 541: 321-330. PMID 28102259 DOI: 10.1038/Nature21349  0.408
2017 Mariathasan S, Turley S, Nickles D, Castiglioni A, Yuen K, Wang Y, Edward E K, Koeppen H, Astarita J, Cubas R, Jhunjhunwala S, Yang Y, Şenbabaoğlu Y, van der Heijden M, Loriot Y, ... Mellman I, et al. TGF-β signalling attenuates tumour response to PD-L1 checkpoint blockade by contributing to retention of T cells in the peritumoural stroma Annals of Oncology. 28: xi30. DOI: 10.1093/Annonc/Mdx760.001  0.408
2016 Ritter AT, Mellman I. Natural killer cell granules converge to avoid collateral damage. The Journal of Cell Biology. PMID 27932575 DOI: 10.1083/Jcb.201612003  0.345
2016 Chung I, Reichelt M, Shao L, Akita RW, Koeppen H, Rangell L, Schaefer G, Mellman I, Sliwkowski MX. High cell-surface density of HER2 deforms cell membranes. Nature Communications. 7: 12742. PMID 27599456 DOI: 10.1038/Ncomms12742  0.372
2016 Mellman I, Hubbard-Lucey VM, Tontonoz MJ, Kalos MD, Chen DS, Allison JP, Drake CG, Levitsky H, Lonberg N, van der Burg SH, Fearon DT, Wherry EJ, Lowy I, Vonderheide RH, Hwu P. De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute. Cancer Immunology Research. 4: 279-88. PMID 27036972 DOI: 10.1158/2326-6066.Cir-16-0045  0.373
2016 Ebert PJ, Cheung J, Yang Y, McNamara E, Hong R, Moskalenko M, Gould SE, Maecker H, Irving BA, Kim JM, Belvin M, Mellman I. MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade. Immunity. PMID 26944201 DOI: 10.1016/J.Immuni.2016.01.024  0.314
2016 Belvin MP, Williams E, Luoh S, Cheung J, Orr C, Chan E, Ebert P, Mellman I, Kim J, Merchant M. Abstract 4905: Effects of MAPK pathway inhibitors in the tumor immune microenvironment Cancer Research. 76: 4905-4905. DOI: 10.1158/1538-7445.Am2016-4905  0.304
2015 Katakam AK, Brightbill H, Franci C, Kung C, Nunez V, Jones C, Peng I, Jeet S, Wu LC, Mellman I, Delamarre L, Austin CD. Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26561586 DOI: 10.1073/Pnas.1520627112  0.359
2015 Baharom F, Thomas S, Bieder A, Hellmér M, Volz J, Sandgren KJ, McInerney GM, Karlsson Hedestam GB, Mellman I, Smed-Sörensen A. Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation. Journal of Immunology (Baltimore, Md. : 1950). 194: 4422-30. PMID 25801434 DOI: 10.4049/Jimmunol.1402671  0.306
2015 Reversat A, Yuseff MI, Lankar D, Malbec O, Obino D, Maurin M, Penmatcha NV, Amoroso A, Sengmanivong L, Gundersen GG, Mellman I, Darchen F, Desnos C, Pierobon P, Lennon-Duménil AM. Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse. Molecular Biology of the Cell. 26: 1273-85. PMID 25631815 DOI: 10.1091/Mbc.E14-09-1373  0.416
2015 Chung I, Mellman I. Single-molecule optical methods analyzing receptor tyrosine kinase activation in living cells. Methods in Molecular Biology (Clifton, N.J.). 1233: 35-44. PMID 25319887 DOI: 10.1007/978-1-4939-1789-1_4  0.307
2015 Lee B, Chalouni C, Nalle S, Doll S, Darwish M, Mellman I, Vandlen R. Abstract 211: A novel FRET assay for the intracellular activation of ADC linkers Cancer Research. 75: 211-211. DOI: 10.1158/1538-7445.Am2015-211  0.361
2015 Schmid P, Kowanetz M, Koeppen H, Zou W, Wistuba I, Kockx M, Kadel E, Chaft J, Rizvi N, Hirsch F, Smith D, Miley N, Leveque V, Shames D, Sandler A, ... Mellman I, et al. 3017 NSCLC with high PD-L1 expression on tumor cells or tumorinfiltrating immune cells represents distinct cancer subtypes European Journal of Cancer. 51: S602. DOI: 10.1016/S0959-8049(16)31661-6  0.35
2015 Chung I, Reichelt M, Dowbenko D, Mellman I, Sliwkowski M. Membrane Deformation by HER2 Overexpression Disrupts Epithelial Integrity Biophysical Journal. 108: 162a. DOI: 10.1016/J.Bpj.2014.11.893  0.375
2014 Yadav M, Jhunjhunwala S, Phung QT, Lupardus P, Tanguay J, Bumbaca S, Franci C, Cheung TK, Fritsche J, Weinschenk T, Modrusan Z, Mellman I, Lill JR, Delamarre L. Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature. 515: 572-6. PMID 25428506 DOI: 10.1038/Nature14001  0.323
2014 Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, Sosman JA, McDermott DF, Powderly JD, Gettinger SN, Kohrt HE, Horn L, Lawrence DP, Rost S, Leabman M, ... ... Mellman I, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 515: 563-7. PMID 25428504 DOI: 10.1038/Nature14011  0.43
2014 Nakamura N, Lill JR, Phung Q, Jiang Z, Bakalarski C, de Mazière A, Klumperman J, Schlatter M, Delamarre L, Mellman I. Endosomes are specialized platforms for bacterial sensing and NOD2 signalling. Nature. 509: 240-4. PMID 24695226 DOI: 10.1038/Nature13133  0.385
2014 Vander Lugt B, Khan AA, Hackney JA, Agrawal S, Lesch J, Zhou M, Lee WP, Park S, Xu M, DeVoss J, Spooner CJ, Chalouni C, Delamarre L, Mellman I, Singh H. Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nature Immunology. 15: 161-7. PMID 24362890 DOI: 10.1038/Ni.2795  0.412
2014 Liang X, Fu C, Cui W, Ober-Blöbaum JL, Zahner SP, Shrikant PA, Clausen BE, Flavell RA, Mellman I, Jiang A. β-catenin mediates tumor-induced immunosuppression by inhibiting cross-priming of CD8⁺ T cells. Journal of Leukocyte Biology. 95: 179-90. PMID 24023259 DOI: 10.1189/Jlb.0613330  0.348
2014 Chung I, Reichelt M, Dowbenko D, Mellman I, Sliwkowski M. Abstract 3330: HER2 overexpression induces membrane deformation that increases cell motility Cancer Research. 74: 3330-3330. DOI: 10.1158/1538-7445.Am2014-3330  0.356
2014 Chung I, Reichelt M, Dowbenko D, Mellman I, Sliwkowski M. HER2 Overexpression Induces Membrane Deformation that Increases Cell Motility Biophysical Journal. 106: 523a. DOI: 10.1016/J.Bpj.2013.11.2917  0.363
2013 Mellman I. Dendritic cells: master regulators of the immune response. Cancer Immunology Research. 1: 145-9. PMID 24777676 DOI: 10.1158/2326-6066.Cir-13-0102  0.352
2013 Mellman I, Yarden Y. Endocytosis and cancer. Cold Spring Harbor Perspectives in Biology. 5: a016949. PMID 24296170 DOI: 10.1101/Cshperspect.A016949  0.375
2013 Mellman I, Emr SD. A Nobel Prize for membrane traffic: vesicles find their journey's end. The Journal of Cell Biology. 203: 559-61. PMID 24215073 DOI: 10.1083/Jcb.201310134  0.327
2013 Chen DS, Mellman I. Oncology meets immunology: the cancer-immunity cycle. Immunity. 39: 1-10. PMID 23890059 DOI: 10.1016/J.Immuni.2013.07.012  0.446
2013 Oh J, Wu N, Baravalle G, Cohn B, Ma J, Lo B, Mellman I, Ishido S, Anderson M, Shin JS. MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells. The Journal of Experimental Medicine. 210: 1069-77. PMID 23712430 DOI: 10.1084/Jem.20122695  0.644
2013 Cohn L, Chatterjee B, Esselborn F, Smed-Sörensen A, Nakamura N, Chalouni C, Lee BC, Vandlen R, Keler T, Lauer P, Brockstedt D, Mellman I, Delamarre L. Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation. The Journal of Experimental Medicine. 210: 1049-63. PMID 23569326 DOI: 10.1084/Jem.20121251  0.608
2013 Irving BA, Cheung J, Yang Y, Moskalenka M, Kowanetz M, Maecker H, Mellman I. MAP kinase inhibitors stimulate T cell and anti-tumor activity in combination with blockade of the PD-L1/PD-1 interaction Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P79  0.321
2012 Chatterjee B, Smed-Sörensen A, Cohn L, Chalouni C, Vandlen R, Lee BC, Widger J, Keler T, Delamarre L, Mellman I. Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells. Blood. 120: 2011-20. PMID 22791285 DOI: 10.1182/Blood-2012-01-402370  0.61
2012 Ma JK, Platt MY, Eastham-Anderson J, Shin JS, Mellman I. MHC class II distribution in dendritic cells and B cells is determined by ubiquitin chain length. Proceedings of the National Academy of Sciences of the United States of America. 109: 8820-7. PMID 22566640 DOI: 10.1073/Pnas.1202977109  0.642
2012 Smed-Sörensen A, Chalouni C, Chatterjee B, Cohn L, Blattmann P, Nakamura N, Delamarre L, Mellman I. Influenza A virus infection of human primary dendritic cells impairs their ability to cross-present antigen to CD8 T cells. Plos Pathogens. 8: e1002572. PMID 22412374 DOI: 10.1371/Journal.Ppat.1002572  0.603
2012 Chung I, Akita R, Shao L, Schaefer G, Sliwkowski M, Mellman I. The Nature of Constitutive Activation of HER2 at the Single Molecule Level Biophysical Journal. 102: 654a. DOI: 10.1016/J.Bpj.2011.11.3560  0.333
2011 Banchereau J, Cohn F, Inaba K, Muller B, Mellman I, Nathan C, Nussenzweig M, O'Garra A, Seder B, Schuler G, Sher A. Remembering Ralph Steinman. The Journal of Experimental Medicine. 208: 2343-7. PMID 22216461 DOI: 10.1084/Jem.20112295  0.416
2011 Mellman I, Nussenzweig M. Retrospective. Ralph M. Steinman (1943-2011). Science (New York, N.Y.). 334: 466. PMID 22034425 DOI: 10.1126/Science.1215136  0.42
2011 Francis SS, Sfakianos J, Lo B, Mellman I. A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells. The Journal of Cell Biology. 193: 219-33. PMID 21444686 DOI: 10.1083/Jcb.201009001  0.626
2011 Delamarre L, Mellman I. Harnessing dendritic cells for immunotherapy. Seminars in Immunology. 23: 2-11. PMID 21377379 DOI: 10.1016/J.Smim.2011.02.001  0.385
2010 Mellman I. Cell biology redux. Molecular Biology of the Cell. 21: 3809-10. PMID 21079023 DOI: 10.1091/Mbc.E10-04-0346  0.38
2010 Togawa A, Sfakianos J, Ishibe S, Suzuki S, Fujigaki Y, Kitagawa M, Mellman I, Cantley LG. Hepatocyte Growth Factor stimulated cell scattering requires ERK and Cdc42-dependent tight junction disassembly. Biochemical and Biophysical Research Communications. 400: 271-7. PMID 20728428 DOI: 10.1016/J.Bbrc.2010.08.060  0.305
2010 Mellman I, Clausen BE. Immunology. Beta-catenin balances immunity. Science (New York, N.Y.). 329: 767-9. PMID 20705838 DOI: 10.1126/Science.1194185  0.318
2010 McCurley N, Mellman I. Monocyte-derived dendritic cells exhibit increased levels of lysosomal proteolysis as compared to other human dendritic cell populations. Plos One. 5: e11949. PMID 20689855 DOI: 10.1371/Journal.Pone.0011949  0.8
2010 Winckler B, Mellman I. Trafficking guidance receptors. Cold Spring Harbor Perspectives in Biology. 2: a001826. PMID 20504966 DOI: 10.1101/Cshperspect.A001826  0.33
2010 Chung I, Akita R, Vandlen R, Toomre D, Schlessinger J, Mellman I. Spatial control of EGF receptor activation by reversible dimerization on living cells. Nature. 464: 783-7. PMID 20208517 DOI: 10.1038/Nature08827  0.306
2010 Platt CD, Ma JK, Chalouni C, Ebersold M, Bou-Reslan H, Carano RA, Mellman I, Delamarre L. Mature dendritic cells use endocytic receptors to capture and present antigens. Proceedings of the National Academy of Sciences of the United States of America. 107: 4287-92. PMID 20142498 DOI: 10.1073/Pnas.0910609107  0.778
2009 Cheever MA, Allison JP, Ferris AS, Finn OJ, Hastings BM, Hecht TT, Mellman I, Prindiville SA, Viner JL, Weiner LM, Matrisian LM. The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5323-37. PMID 19723653 DOI: 10.1158/1078-0432.Ccr-09-0737  0.316
2009 Farr GA, Hull M, Mellman I, Caplan MJ. Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells. The Journal of Cell Biology. 186: 269-82. PMID 19620635 DOI: 10.1083/Jcb.200901021  0.339
2009 Demento SL, Eisenbarth SC, Foellmer HG, Platt C, Caplan MJ, Mark Saltzman W, Mellman I, Ledizet M, Fikrig E, Flavell RA, Fahmy TM. Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy. Vaccine. 27: 3013-21. PMID 19428913 DOI: 10.1016/J.Vaccine.2009.03.034  0.665
2009 Becker SM, Delamarre L, Mellman I, Andrews NW. Differential role of the Ca(2+) sensor synaptotagmin VII in macrophages and dendritic cells. Immunobiology. 214: 495-505. PMID 19157638 DOI: 10.1016/J.Imbio.2008.11.006  0.397
2009 Goldszmid RS, Coppens I, Lev A, Caspar P, Mellman I, Sher A. Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. The Journal of Experimental Medicine. 206: 399-410. PMID 19153244 DOI: 10.1084/Jem.20082108  0.372
2009 Mao YS, Yamaga M, Zhu X, Wei Y, Sun HQ, Wang J, Yun M, Wang Y, Di Paolo G, Bennett M, Mellman I, Abrams CS, De Camilli P, Lu CY, Yin HL. Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis. The Journal of Cell Biology. 184: 281-96. PMID 19153220 DOI: 10.1083/jcb.200806121  0.523
2009 Chung I, Toomre D, Schlessinger J, Mellman I. Spontaneously Formed EGFR Dimers Are Primed For Activation Biophysical Journal. 96: 368a. DOI: 10.1016/J.Bpj.2008.12.1984  0.315
2008 Mellman I, Nelson WJ. Coordinated protein sorting, targeting and distribution in polarized cells. Nature Reviews. Molecular Cell Biology. 9: 833-45. PMID 18946473 DOI: 10.1038/Nrm2525  0.388
2008 Maday S, Anderson E, Chang HC, Shorter J, Satoh A, Sfakianos J, Fölsch H, Anderson JM, Walther Z, Mellman I. A PDZ-binding motif controls basolateral targeting of syndecan-1 along the biosynthetic pathway in polarized epithelial cells. Traffic (Copenhagen, Denmark). 9: 1915-24. PMID 18764819 DOI: 10.1111/J.1600-0854.2008.00805.X  0.729
2008 Bloom O, Unternaehrer JJ, Jiang A, Shin JS, Delamarre L, Allen P, Mellman I. Spinophilin participates in information transfer at immunological synapses. The Journal of Cell Biology. 181: 203-11. PMID 18411312 DOI: 10.1083/Jcb.200711149  0.708
2008 Di Pucchio T, Chatterjee B, Smed-Sörensen A, Clayton S, Palazzo A, Montes M, Xue Y, Mellman I, Banchereau J, Connolly JE. Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I. Nature Immunology. 9: 551-7. PMID 18376401 DOI: 10.1038/Ni.1602  0.626
2008 Ackerman ME, Chalouni C, Schmidt MM, Raman VV, Ritter G, Old LJ, Mellman I, Wittrup KD. A33 antigen displays persistent surface expression. Cancer Immunology, Immunotherapy : Cii. 57: 1017-27. PMID 18236042 DOI: 10.1007/S00262-007-0433-X  0.319
2008 Reig N, Jiang A, Couture R, Sutterwala FS, Ogura Y, Flavell RA, Mellman I, van der Goot FG. Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxin. Cellular Microbiology. 10: 1190-207. PMID 18194483 DOI: 10.1111/J.1462-5822.2008.01121.X  0.347
2007 Sfakianos J, Togawa A, Maday S, Hull M, Pypaert M, Cantley L, Toomre D, Mellman I. Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells. The Journal of Cell Biology. 179: 1133-40. PMID 18070914 DOI: 10.1083/Jcb.200709111  0.749
2007 Jiang A, Bloom O, Ono S, Cui W, Unternaehrer J, Jiang S, Whitney JA, Connolly J, Banchereau J, Mellman I. Disruption of E-cadherin-mediated adhesion induces a functionally distinct pathway of dendritic cell maturation. Immunity. 27: 610-24. PMID 17936032 DOI: 10.1016/J.Immuni.2007.08.015  0.705
2007 Lande R, Gregorio J, Facchinetti V, Chatterjee B, Wang YH, Homey B, Cao W, Wang YH, Su B, Nestle FO, Zal T, Mellman I, Schröder JM, Liu YJ, Gilliet M. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature. 449: 564-9. PMID 17873860 DOI: 10.1038/Nature06116  0.539
2007 Mellman I. Private lives: reflections and challenges in understanding the cell biology of the immune system. Science (New York, N.Y.). 317: 625-7. PMID 17673653 DOI: 10.1126/Science.1142955  0.334
2007 Unternaehrer JJ, Chow A, Pypaert M, Inaba K, Mellman I. The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface. Proceedings of the National Academy of Sciences of the United States of America. 104: 234-9. PMID 17190803 DOI: 10.1073/Pnas.0609665104  0.646
2007 Schuck S, Gerl MJ, Ang A, Manninen A, Keller P, Mellman I, Simons K. Rab10 is involved in basolateral transport in polarized Madin-Darby canine kidney cells. Traffic (Copenhagen, Denmark). 8: 47-60. PMID 17132146 DOI: 10.1111/J.1600-0854.2006.00506.X  0.693
2006 Shin JS, Ebersold M, Pypaert M, Delamarre L, Hartley A, Mellman I. Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination. Nature. 444: 115-8. PMID 17051151 DOI: 10.1038/Nature05261  0.404
2006 Kim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, Flavell RA. Modulation of cell adhesion and motility in the immune system by Myo1f. Science (New York, N.Y.). 314: 136-9. PMID 17023661 DOI: 10.1126/Science.1131920  0.346
2006 Delamarre L, Couture R, Mellman I, Trombetta ES. Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis. The Journal of Experimental Medicine. 203: 2049-55. PMID 16908625 DOI: 10.1084/Jem.20052442  0.415
2006 Shim JH, Xiao C, Hayden MS, Lee KY, Trombetta ES, Pypaert M, Nara A, Yoshimori T, Wilm B, Erdjument-Bromage H, Tempst P, Hogan BL, Mellman I, Ghosh S. CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. The Journal of Cell Biology. 172: 1045-56. PMID 16567502 DOI: 10.1083/Jcb.200509041  0.368
2006 Hua W, Sheff D, Toomre D, Mellman I. Vectorial insertion of apical and basolateral membrane proteins in polarized epithelial cells revealed by quantitative 3D live cell imaging. The Journal of Cell Biology. 172: 1035-44. PMID 16567501 DOI: 10.1083/Jcb.200512012  0.404
2006 Zwickey HL, Unternaehrer JJ, Mellman I. Presentation of self-antigens on MHC class II molecules during dendritic cell maturation. International Immunology. 18: 199-209. PMID 16361313 DOI: 10.1093/Intimm/Dxh363  0.408
2005 Touret N, Paroutis P, Terebiznik M, Harrison RE, Trombetta S, Pypaert M, Chow A, Jiang A, Shaw J, Yip C, Moore HP, van der Wel N, Houben D, Peters PJ, de Chastellier C, ... Mellman I, et al. Quantitative and dynamic assessment of the contribution of the ER to phagosome formation. Cell. 123: 157-70. PMID 16213220 DOI: 10.1016/J.Cell.2005.08.018  0.62
2005 Anderson E, Maday S, Sfakianos J, Hull M, Winckler B, Sheff D, Fölsch H, Mellman I. Transcytosis of NgCAM in epithelial cells reflects differential signal recognition on the endocytic and secretory pathways. The Journal of Cell Biology. 170: 595-605. PMID 16087710 DOI: 10.1083/Jcb.200506051  0.747
2005 Yan J, Wolff MJ, Unternaehrer J, Mellman I, Mamula MJ. Targeting antigen to CD19 on B cells efficiently activates T cells. International Immunology. 17: 869-77. PMID 15967786 DOI: 10.1093/Intimm/Dxh266  0.371
2005 Mellman I. Antigen processing and presentation by dendritic cells: cell biological mechanisms. Advances in Experimental Medicine and Biology. 560: 63-7. PMID 15932021 DOI: 10.1007/0-387-24180-9_9  0.439
2005 Trombetta ES, Mellman I. Cell biology of antigen processing in vitro and in vivo. Annual Review of Immunology. 23: 975-1028. PMID 15771591 DOI: 10.1146/Annurev.Immunol.22.012703.104538  0.425
2005 Delamarre L, Pack M, Chang H, Mellman I, Trombetta ES. Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science (New York, N.Y.). 307: 1630-4. PMID 15761154 DOI: 10.1126/Science.1108003  0.423
2005 Chow AY, Mellman I. Old lysosomes, new tricks: MHC II dynamics in DCs. Trends in Immunology. 26: 72-8. PMID 15668121 DOI: 10.1016/J.It.2004.11.008  0.669
2005 Chow AY, Unternaehrer JJ, Mellman I. MHC Class II Measuring Immunity: Basic Biology and Clinical Assessment. 12-22. DOI: 10.1016/B978-012455900-4/50264-6  0.54
2004 Ang AL, Taguchi T, Francis S, Fölsch H, Murrells LJ, Pypaert M, Warren G, Mellman I. Recycling endosomes can serve as intermediates during transport from the Golgi to the plasma membrane of MDCK cells. The Journal of Cell Biology. 167: 531-43. PMID 15534004 DOI: 10.1083/Jcb.200408165  0.776
2004 Meyer zum Bueschenfelde CO, Unternaehrer J, Mellman I, Bottomly K. Regulated recruitment of MHC class II and costimulatory molecules to lipid rafts in dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 6119-24. PMID 15528348 DOI: 10.4049/Jimmunol.173.10.6119  0.411
2004 Matsuo M, Nagata Y, Sato E, Atanackovic D, Valmori D, Chen YT, Ritter G, Mellman I, Old LJ, Gnjatic S. IFN-gamma enables cross-presentation of exogenous protein antigen in human Langerhans cells by potentiating maturation. Proceedings of the National Academy of Sciences of the United States of America. 101: 14467-72. PMID 15383663 DOI: 10.1073/Pnas.0405947101  0.383
2004 Steinman RM, Mellman I. The JEM and the JCB: a synergistic partnership. The Journal of Cell Biology. 166: 611. PMID 15337771 DOI: 10.1083/jcb.200408039  0.488
2004 Steinman RM, Mellman I. Immunotherapy: bewitched, bothered, and bewildered no more. Science (New York, N.Y.). 305: 197-200. PMID 15247468 DOI: 10.1126/Science.1099688  0.563
2004 Duffield A, Fölsch H, Mellman I, Caplan MJ. Sorting of H,K-ATPase beta-subunit in MDCK and LLC-PK cells is independent of mu 1B adaptin expression. Traffic (Copenhagen, Denmark). 5: 449-61. PMID 15117319 DOI: 10.1111/J.1398-9219.2004.00192.X  0.321
2004 Chang HC, Hull M, Mellman I. The J-domain protein Rme-8 interacts with Hsc70 to control clathrin-dependent endocytosis in Drosophila. The Journal of Cell Biology. 164: 1055-64. PMID 15051737 DOI: 10.1083/Jcb.200311084  0.319
2004 Yeaman C, Ayala MI, Wright JR, Bard F, Bossard C, Ang A, Maeda Y, Seufferlein T, Mellman I, Nelson WJ, Malhotra V. Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network. Nature Cell Biology. 6: 106-12. PMID 14743217 DOI: 10.1038/Ncb1090  0.678
2004 Steinman RM, Mellman I. The JEM and the JCB: A synergistic partnership Journal of Experimental Medicine. 200: 549. DOI: 10.1084/Jem.20041570  0.534
2003 Fölsch H, Pypaert M, Maday S, Pelletier L, Mellman I. The AP-1A and AP-1B clathrin adaptor complexes define biochemically and functionally distinct membrane domains. The Journal of Cell Biology. 163: 351-62. PMID 14581457 DOI: 10.1083/Jcb.200309020  0.733
2003 Ang AL, Fölsch H, Koivisto UM, Pypaert M, Mellman I. The Rab8 GTPase selectively regulates AP-1B-dependent basolateral transport in polarized Madin-Darby canine kidney cells. The Journal of Cell Biology. 163: 339-50. PMID 14581456 DOI: 10.1083/Jcb.200307046  0.683
2003 Delamarre L, Holcombe H, Mellman I. Presentation of exogenous antigens on major histocompatibility complex (MHC) class I and MHC class II molecules is differentially regulated during dendritic cell maturation. The Journal of Experimental Medicine. 198: 111-22. PMID 12835477 DOI: 10.1084/Jem.20021542  0.424
2003 Trombetta ES, Ebersold M, Garrett W, Pypaert M, Mellman I. Activation of lysosomal function during dendritic cell maturation. Science (New York, N.Y.). 299: 1400-3. PMID 12610307 DOI: 10.1126/Science.1080106  0.646
2003 Mellman I. Cell Biology of Antigen Processing Annual Review of Immunology. DOI: 10.1146/Annurev.Immunol.22.012703  0.366
2002 Chang HC, Newmyer SL, Hull MJ, Ebersold M, Schmid SL, Mellman I. Hsc70 is required for endocytosis and clathrin function in Drosophila. The Journal of Cell Biology. 159: 477-87. PMID 12427870 DOI: 10.1083/Jcb.200205086  0.319
2002 Holcombe H, Mellman I, Janeway CA, Bottomly K, Dittel BN. The immunosuppressive agent 15-deoxyspergualin functions by inhibiting cell cycle progression and cytokine production following naive T cell activation. Journal of Immunology (Baltimore, Md. : 1950). 169: 4982-9. PMID 12391212 DOI: 10.4049/Jimmunol.169.9.4982  0.339
2002 Chow A, Toomre D, Garrett W, Mellman I. Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature. 418: 988-94. PMID 12198549 DOI: 10.1038/Nature01006  0.761
2002 Nagata Y, Ono S, Matsuo M, Gnjatic S, Valmori D, Ritter G, Garrett W, Old LJ, Mellman I. Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations. Proceedings of the National Academy of Sciences of the United States of America. 99: 10629-34. PMID 12138174 DOI: 10.1073/Pnas.112331099  0.639
2002 Sugimoto H, Sugahara M, Fölsch H, Koide Y, Nakatsu F, Tanaka N, Nishimura T, Furukawa M, Mullins C, Nakamura N, Mellman I, Ohno H. Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells. Molecular Biology of the Cell. 13: 2374-82. PMID 12134076 DOI: 10.1091/Mbc.E01-10-0096  0.388
2002 Sheff D, Pelletier L, O'Connell CB, Warren G, Mellman I. Transferrin receptor recycling in the absence of perinuclear recycling endosomes. The Journal of Cell Biology. 156: 797-804. PMID 11877458 DOI: 10.1083/Jcb.20111048  0.399
2002 Sheff DR, Kroschewski R, Mellman I. Actin dependence of polarized receptor recycling in Madin-Darby canine kidney cell endosomes. Molecular Biology of the Cell. 13: 262-75. PMID 11809838 DOI: 10.1091/Mbc.01-07-0320  0.389
2001 Balamuth F, Leitenberg D, Unternaehrer J, Mellman I, Bottomly K. Distinct patterns of membrane microdomain partitioning in Th1 and th2 cells. Immunity. 15: 729-38. PMID 11728335 DOI: 10.1016/S1074-7613(01)00223-0  0.361
2001 Mellman I, Steinman RM. Dendritic cells: specialized and regulated antigen processing machines. Cell. 106: 255-8. PMID 11509172 DOI: 10.1016/S0092-8674(01)00449-4  0.584
2001 Koivisto UM, Hubbard AL, Mellman I. A novel cellular phenotype for familial hypercholesterolemia due to a defect in polarized targeting of LDL receptor. Cell. 105: 575-85. PMID 11389828 DOI: 10.1016/S0092-8674(01)00371-3  0.633
2001 Fölsch H, Pypaert M, Schu P, Mellman I. Distribution and function of AP-1 clathrin adaptor complexes in polarized epithelial cells. The Journal of Cell Biology. 152: 595-606. PMID 11157985 DOI: 10.1083/Jcb.152.3.595  0.359
2000 Fong DC, Brauweiler A, Minskoff SA, Bruhns P, Tamir I, Mellman I, Daeron M, Cambier JC. Mutational analysis reveals multiple distinct sites within Fc gamma receptor IIB that function in inhibitory signaling. Journal of Immunology (Baltimore, Md. : 1950). 165: 4453-62. PMID 11035084 DOI: 10.4049/Jimmunol.165.8.4453  0.33
2000 Garrett WS, Chen LM, Kroschewski R, Ebersold M, Turley S, Trombetta S, Galán JE, Mellman I. Developmental control of endocytosis in dendritic cells by Cdc42. Cell. 102: 325-34. PMID 10975523 DOI: 10.1016/S0092-8674(00)00038-6  0.622
2000 Mellman I. Quo vadis: polarized membrane recycling in motility and phagocytosis. The Journal of Cell Biology. 149: 529-30. PMID 10791966 DOI: 10.1083/Jcb.149.3.529  0.341
2000 Turley SJ, Inaba K, Garrett WS, Ebersold M, Unternaehrer J, Steinman RM, Mellman I. Transport of peptide-MHC class II complexes in developing dendritic cells. Science (New York, N.Y.). 288: 522-7. PMID 10775112 DOI: 10.1126/Science.288.5465.522  0.75
2000 Pierre P, Shachar I, Matza D, Gatti E, Flavell RA, Mellman I. Invariant chain controls H2-M proteolysis in mouse splenocytes and dendritic cells. The Journal of Experimental Medicine. 191: 1057-62. PMID 10727467 DOI: 10.1084/Jem.191.6.1057  0.397
2000 Inaba K, Turley S, Iyoda T, Yamaide F, Shimoyama S, Reis e Sousa C, Germain RN, Mellman I, Steinman RM. The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli. The Journal of Experimental Medicine. 191: 927-36. PMID 10727455 DOI: 10.1084/Jem.191.6.927  0.655
2000 Gatti E, Velleca MA, Biedermann BC, Ma W, Unternaehrer J, Ebersold MW, Medzhitov R, Pober JS, Mellman I. Large-scale culture and selective maturation of human Langerhans cells from granulocyte colony-stimulating factor-mobilized CD34+ progenitors. Journal of Immunology (Baltimore, Md. : 1950). 164: 3600-7. PMID 10725716 DOI: 10.4049/Jimmunol.164.7.3600  0.391
2000 Steinman RM, Turley S, Mellman I, Inaba K. The induction of tolerance by dendritic cells that have captured apoptotic cells. The Journal of Experimental Medicine. 191: 411-6. PMID 10662786 DOI: 10.1084/Jem.191.3.411  0.645
1999 Kroschewski R, Hall A, Mellman I. Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells Nature Cell Biology. 1: 8-13. PMID 10559857 DOI: 10.1038/8977  0.4
1999 Fölsch H, Ohno H, Bonifacino JS, Mellman I. A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cells Cell. 99: 189-198. PMID 10535737 DOI: 10.1016/S0092-8674(00)81650-5  0.411
1999 Steinman RM, Inaba K, Turley S, Pierre P, Mellman I. Antigen capture, processing, and presentation by dendritic cells: recent cell biological studies. Human Immunology. 60: 562-7. PMID 10426272 DOI: 10.1016/S0198-8859(99)00030-0  0.665
1999 Ohno H, Tomemori T, Nakatsu F, Okazaki Y, Aguilar RC, Foelsch H, Mellman I, Saito T, Shirasawa T, Bonifacino JS. μ1B, a novel adaptor medium chain expressed in polarized epithelial cells Febs Letters. 449: 215-220. PMID 10338135 DOI: 10.1016/S0014-5793(99)00432-9  0.393
1999 Sheff DR, Daro EA, Hull M, Mellman I. The receptors recycling pathway contains two distinct populations of early endosomes with different sorting functions Journal of Cell Biology. 145: 123-139. PMID 10189373 DOI: 10.1083/Jcb.145.1.123  0.365
1999 Winckler B, Forscher P, Mellman I. A diffusion barrier maintains distribution of membrane proteins in polarized neurons. Nature. 397: 698-701. PMID 10067893 DOI: 10.1038/17806  0.336
1999 Cleveland DW, Nelson WJ, Franke W, Reichardt L, Fuchs E, Schekman R, Mellman I, Yamada KM. The Journal of Cell Biology: Letter from the editors Journal of Cell Biology. 144: 805. DOI: 10.1083/Jcb.144.5.805  0.319
1999 Albert ML, Bhardwaj N, Steinman RM, Turley S, Garrett W, Mellman I, Inaba K. Uptake and presentation of phagocytosed antigens by dendritic cells Advances in Cellular and Molecular Biology of Membranes and Organelles. 5: 363-378. DOI: 10.1016/S1874-5172(99)80040-6  0.751
1998 Inaba K, Turley S, Yamaide F, Iyoda T, Mahnke K, Inaba M, Pack M, Subklewe M, Sauter B, Sheff D, Albert M, Bhardwaj N, Mellman I, Steinman RM. Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells. The Journal of Experimental Medicine. 188: 2163-73. PMID 9841929 DOI: 10.1084/Jem.188.11.2163  0.662
1998 Lazzarino DA, Blier P, Mellman I. The monomeric guanosine triphosphatase rab4 controls an essential step on the pathway of receptor-mediated antigen processing in B cells Journal of Experimental Medicine. 188: 1769-1774. PMID 9815254 DOI: 10.1084/jem.188.10.1769  0.307
1998 Mellman I, Turley SJ, Steinman RM. Antigen processing for amateurs and professionals. Trends in Cell Biology. 8: 231-7. PMID 9695847 DOI: 10.1016/S0962-8924(98)01276-8  0.683
1998 Pierre P, Mellman I. Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells Cell. 93: 1135-1145. PMID 9657147 DOI: 10.1016/S0092-8674(00)81458-0  0.38
1998 Pierre P, Mellman I. Exploring the mechanisms of antigen processing by cell fractionation Current Opinion in Immunology. 10: 145-153. PMID 9602302 DOI: 10.1016/S0952-7915(98)80242-2  0.411
1998 Talmor M, Mirza A, Turley S, Mellman I, Hoffman LA, Steinman RM. Generation or large numbers of immature and mature dendritic cells from rat bone marrow cultures. European Journal of Immunology. 28: 811-7. PMID 9541575 DOI: 10.1002/(Sici)1521-4141(199803)28:03<811::Aid-Immu811>3.0.Co;2-S  0.644
1998 Zacchi P, Stenmark H, Parton RG, Orioli D, Lim F, Giner A, Mellman I, Zerial M, Murphy C. Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells. The Journal of Cell Biology. 140: 1039-53. PMID 9490718 DOI: 10.1083/Jcb.140.5.1039  0.439
1997 Daro E, Sheff D, Gomez M, Kreis T, Mellman I. Inhibition of endosome function in CHO cells bearing a temperature- sensitive defect in the coatomer (COPI) component ε-COP Journal of Cell Biology. 139: 1747-1759. PMID 9412469 DOI: 10.1083/Jcb.139.7.1747  0.359
1997 Drake JR, Webster P, Gambier JC, Mellman I. Delivery of B cell receptor-internalized antigen to endosomes and class II vesicles Journal of Experimental Medicine. 186: 1299-1306. PMID 9334369 DOI: 10.1084/Jem.186.8.1299  0.418
1997 Ayad N, Hull M, Mellman I. Mitotic phosphorylation of rab4 prevents binding to a specific receptor on endosome membranes Embo Journal. 16: 4497-4507. PMID 9303294 DOI: 10.1093/Emboj/16.15.4497  0.359
1997 Pierre P, Turley SJ, Meltzer J, Mirza A, Steinman R, Mellman I. Localization and intracellular transport of MHC class II molecules in bone marrow-derived dendritic cells Advances in Experimental Medicine and Biology. 417: 179-182. PMID 9286358 DOI: 10.1007/978-1-4757-9966-8_30  0.676
1997 Pierre P, Turley SJ, Gatti E, Hull M, Meltzer J, Mirza A, Inaba K, Steinman RM, Mellman I. Developmental regulation of MHC class II transport in mouse dendritic cells. Nature. 388: 787-92. PMID 9285592 DOI: 10.1038/42039  0.677
1997 Schekman R, Mellman I. Does COPI go both ways? Cell. 90: 197-200. PMID 9244292 DOI: 10.1016/S0092-8674(00)80326-8  0.345
1997 Brachet V, Raposo G, Amigorena S, Mellman I. Ii chain controls the transport of major histocompatibility complex class II molecules to and from lysosomes Journal of Cell Biology. 137: 51-65. PMID 9105036 DOI: 10.1083/Jcb.137.1.51  0.351
1996 Mellman I. Endocytosis and molecular sorting Annual Review of Cell and Developmental Biology. 12: 575-625. PMID 8970738 DOI: 10.1146/Annurev.Cellbio.12.1.575  0.391
1996 Mellman I. Membranes and sorting Current Opinion in Cell Biology. 8: 497-498. PMID 8791461 DOI: 10.1016/S0955-0674(96)80026-3  0.302
1996 Daro E, van der Sluijs P, Galli T, Mellman I. Rab4 and cellubrevin define different early endosome populations on the pathway of transferrin receptor recycling. Proceedings of the National Academy of Sciences of the United States of America. 93: 9559-64. PMID 8790369 DOI: 10.1073/Pnas.93.18.9559  0.321
1996 Cavenagh MM, Whitney JA, Carroll K, Zhang CJ, Boman AL, Rosenwald AG, Mellman I, Kahn RA. Intracellular distribution of Arf proteins in mammalian cells: Arf6 is uniquely localized to the plasma membrane Journal of Biological Chemistry. 271: 21767-21774. PMID 8702973 DOI: 10.1074/Jbc.271.36.21767  0.365
1996 Sheff D, Lowe M, Kreis TE, Mellman I. Biochemical heterogeneity and phosphorylation of coatomer subunits. The Journal of Biological Chemistry. 271: 7230-6. PMID 8636162 DOI: 10.1074/Jbc.271.12.7230  0.319
1996 Pierre P, Denzin LK, Hammond C, Drake JR, Amigorena S, Cresswell P, Mellman I. HLA-DM is localized to conventional and unconventional MHC class II-Containing endocytic compartments Immunity. 4: 229-239. PMID 8624813 DOI: 10.1016/S1074-7613(00)80431-8  0.331
1995 Whitney JA, Gomez M, Sheff D, Kreis TE, Mellman I. Cytoplasmic coat proteins involved in endosome function. Cell. 83: 703-13. PMID 8521487 DOI: 10.1016/0092-8674(95)90183-3  0.376
1995 Amigorena S, Webster P, Drake J, Newcomb J, Cresswell P, Mellman I. Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles Journal of Experimental Medicine. 181: 1729-1741. PMID 7722451 DOI: 10.1084/Jem.181.5.1729  0.323
1995 D'Ambrosio D, Hippen KL, Minskoff SA, Mellman I, Pani G, Siminovitch KA, Cambier JC. Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by FcγRIIB1 Science. 268: 293-297. PMID 7716523 DOI: 10.1126/Science.7716523  0.34
1995 Mellman I. Enigma variations: Protein mediators of membrane fusion Cell. 82: 869-872. PMID 7553845 DOI: 10.1016/0092-8674(95)90018-7  0.326
1995 Mellman I, Pierre P, Amigorena S. Lonely MHC molecules seeking immunogenic peptides for meaningful relationships Current Opinion in Cell Biology. 7: 564-572. PMID 7495577 DOI: 10.1016/0955-0674(95)80014-X  0.343
1994 Elliott EA, Drake JR, Amigorena S, Elsemore J, Webster P, Mellman I, Flavell RA. The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules Journal of Experimental Medicine. 179: 681-694. PMID 8294875 DOI: 10.1084/Jem.179.2.681  0.333
1994 Amigorena S, Drake JR, Webster P, Mellman I. Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes Nature. 369: 113-120. PMID 8177316 DOI: 10.1038/369113A0  0.362
1994 Matter K, Yamamoto EM, Mellman I. Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells Journal of Cell Biology. 126: 991-1004. PMID 8051216 DOI: 10.1083/Jcb.126.4.991  0.349
1994 Matter K, Mellman I. Mechamisms of cell polarity: sorting and transport in epithelial cells Current Opinion in Cell Biology. 6: 545-554. PMID 7986532 DOI: 10.1016/0955-0674(94)90075-2  0.402
1994 Bacon RA, Cohen CJ, Lewin DA, Mellman I. Dictyostelium discoideum mutants with temperature-sensitive defects in endocytosis Journal of Cell Biology. 127: 387-399. PMID 7929583 DOI: 10.1083/Jcb.127.2.387  0.325
1993 Matter K, Whitney JA, Yamamoto EM, Mellman I. Common signals control low density lipoprotein receptor sorting in endosomes and the Golgi complex of MDCK cells Cell. 74: 1053-1064. PMID 8402881 DOI: 10.1016/0092-8674(93)90727-8  0.381
1993 Mellman I, Yamamoto E, Whitney JA, Kim M, Hunziker W, Matter K. Molecular sorting in polarized and non-polarized cells: common problems, common solutions Journal of Cell Science. Supplement. 17: 1-7. PMID 8144683 DOI: 10.1242/Jcs.1993.Supplement_17.1  0.41
1992 Miettinen HM, Matter K, Hunziker W, Rose JK, Mellman I. Fc receptor endocytosis is controlled by a cytoplasmic domain determinant that actively prevents coated pit localization. The Journal of Cell Biology. 116: 875-88. PMID 1734021 DOI: 10.1083/Jcb.116.4.875  0.311
1992 Hunziker W, Whitney JA, Mellman I. Brefeldin A and the endocytic pathway Possible implications for membrane traffic and sorting Febs Letters. 307: 93-96. PMID 1639200 DOI: 10.1016/0014-5793(92)80908-Y  0.355
1992 Harter C, Mellman I. Transport of the lysosomal membrane glycoprotein Igp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane Journal of Cell Biology. 117: 311-325. PMID 1560028 DOI: 10.1083/Jcb.117.2.311  0.4
1992 Amigorena S, Bonnerot C, Drake JR, Choquet D, Hunziker W, Guillet JG, Webster P, Sautes C, Mellman I, Fridman WH. Cytoplasmic domain heterogeneity and functions of IgG Fc receptors in B lymphocytes. Science (New York, N.Y.). 256: 1808-12. PMID 1535455 DOI: 10.1126/Science.1535455  0.375
1992 van der Sluijs P, Hull M, Webster P, Mâle P, Goud B, Mellman I. The small GTP-binding protein rab4 controls an early sorting event on the endocytic pathway Cell. 70: 729-740. PMID 1516131 DOI: 10.1016/0092-8674(92)90307-X  0.364
1992 Podbiliewicz B, Mellman I. [20] Reconstitution of endocytosis and recycling using perforated Madin- Darby canine kidney cells Methods in Enzymology. 219: 198-211. PMID 1487993 DOI: 10.1016/0076-6879(92)19022-X  0.424
1992 Van Der Sluijs P, Hull M, Huber LA, Mâle P, Goud B, Mellman I. Reversible phosphorylation - Dephosphorylation determines the localization of rab4 during the cell cycle Embo Journal. 11: 4379-4389. PMID 1425574 DOI: 10.1002/J.1460-2075.1992.Tb05538.X  0.329
1992 Matter K, Hunziker W, Mellman I. Basolateral sorting of LDL receptor in MDCK cells: The cytoplasmic domain contains two tyrosine-dependent targeting determinants Cell. 71: 741-753. PMID 1423629 DOI: 10.1016/0092-8674(92)90551-M  0.372
1991 Hunziker W, Whitney JA, Mellman I. Selective inhibition of transcytosis by brefeldin A in MDCK cells Cell. 67: 617-627. PMID 1934063 DOI: 10.1016/0092-8674(91)90535-7  0.387
1991 Hunziker W, Harter C, Matter K, Mellman I. Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant. Cell. 66: 907-20. PMID 1909606 DOI: 10.1016/0092-8674(91)90437-4  0.376
1991 Van Der Sluijs P, Hull M, Zahraoui A, Tavitian A, Goud B, Mellman I. The small GTP-binding protein rab4 is associated with early endosomes. Proceedings of the National Academy of Sciences of the United States of America. 88: 6313-7. PMID 1906178 DOI: 10.1016/0962-8924(91)90014-Z  0.381
1990 Hunziker W, Mellman I. Expression of macrophage-lymphocyte Fc receptors in Madin-Darby canine kidney cells: polarity and transcytosis differ for isoforms with or without coated pit localization domains. The Journal of Cell Biology. 109: 3291-302. PMID 2574723 DOI: 10.1083/Jcb.109.6.3291  0.397
1990 Joiner KA, Fuhrman SA, Miettinen HM, Kasper LH, Mellman I. Toxoplasma gondii: Fusion competence of parasitophorous vacuoles in Fc receptor-transfected fibroblasts Science. 249: 641-646. PMID 2200126 DOI: 10.1126/Science.2200126  0.371
1990 Hunziker W, Koch T, Whitney JA, Mellman I. Fc receptor phosphorylation during receptor-mediated control of B-cell activation. Nature. 345: 628-32. PMID 2190097 DOI: 10.1038/345628A0  0.405
1990 Granger BL, Green SA, Gabel CA, Howe CL, Mellman I, Helenius A. Characterization and cloning of lgp110, a lysosomal membrane glycoprotein from mouse and rat cells. The Journal of Biological Chemistry. 265: 12036-43. PMID 2142158  0.624
1990 Hunziker W, Mâle P, Mellman I. Differential microtubule requirements for transcytosis in MDCK cells. The Embo Journal. 9: 3515-3525. DOI: 10.1002/J.1460-2075.1990.Tb07560.X  0.392
1990 Podbilewicz B, Mellman I. ATP and cytosol requirements for transferrin recycling in intact and disrupted MDCK cells. The Embo Journal. 9: 3477-3487. DOI: 10.1002/J.1460-2075.1990.Tb07556.X  0.388
1989 Mellman I, Koch T, Healey G, Hunziker W, Lewis V, Plutner H, Miettinen H, Vaux D, Moore K, Stuart S. Structure and function of Fc receptors on macrophages and lymphocytes. Journal of Cell Science. Supplement. 9: 45-65. PMID 2978517 DOI: 10.1242/Jcs.1988.Supplement_9.3  0.351
1989 Schmid S, Fuchs R, Kielian M, Helenius A, Mellman I. Acidification of endosome subpopulations in wild-type Chinese hamster ovary cells and temperature-sensitive acidification-defective mutants. The Journal of Cell Biology. 108: 1291-300. PMID 2925786 DOI: 10.1083/Jcb.108.4.1291  0.657
1989 Geuze HJ, Stoorvogel W, Strous GJ, Slot JW, Bleekemolen JE, Mellman I. Sorting of mannose 6-phosphate receptors and lysosomal membrane proteins in endocytic vesicles. The Journal of Cell Biology. 107: 2491-501. PMID 2849607 DOI: 10.1083/jcb.107.6.2491  0.323
1989 Miettinen HM, Rose JK, Mellman I. Fc receptor isoforms exhibit distinct abilities for coated pit localization as a result of cytoplasmic domain heterogeneity. Cell. 58: 317-27. PMID 2568890 DOI: 10.1016/0092-8674(89)90846-5  0.304
1989 Fuchs R, Schmid S, Mellman I. A possible role for Na+,K+-ATPase in regulating ATP-dependent endosome acidification. Proceedings of the National Academy of Sciences of the United States of America. 86: 539-43. PMID 2536167 DOI: 10.1073/Pnas.86.2.539  0.329
1988 Marsh M, Kern H, Harms E, Schmid S, Mellman I, Helenius A. Co-fractionation of BHK-21 cell endosomes and lysosomes by free-flow electrophoresis. Progress in Clinical and Biological Research. 270: 21-33. PMID 3413159  0.599
1988 Copeland CS, Zimmer KP, Wagner KR, Healey GA, Mellman I, Helenius A. Folding, trimerization, and transport are sequential events in the biogenesis of influenza virus hemagglutinin. Cell. 53: 197-209. PMID 3359486 DOI: 10.1016/0092-8674(88)90381-9  0.645
1988 Schmid SL, Fuchs R, Male P, Mellman I. Two distinct subpopulations of endosomes involved in membrane recycling and transport to lysosomes. Cell. 52: 73-83. PMID 3345561 DOI: 10.1016/0092-8674(88)90532-6  0.384
1988 Mellman I, Fuchs R, Schmid S, Helenius A. The control of intracellular membrane traffic: implications for Ca++ and phosphate transport. Progress in Clinical and Biological Research. 252: 101-8. PMID 3279424  0.597
1988 Howe CL, Granger BL, Hull M, Green SA, Gabel CA, Helenius A, Mellman I. Derived protein sequence, oligosaccharides, and membrane insertion of the 120-kDa lysosomal membrane glycoprotein (lgp120): identification of a highly conserved family of lysosomal membrane glycoproteins. Proceedings of the National Academy of Sciences of the United States of America. 85: 7577-81. PMID 3174652 DOI: 10.1073/Pnas.85.20.7577  0.659
1988 Griffiths G, Hoflack B, Simons K, Mellman I, Kornfeld S. The mannose 6-phosphate receptor and the biogenesis of lysosomes. Cell. 52: 329-41. PMID 2964276 DOI: 10.1016/S0092-8674(88)80026-6  0.346
1988 Vaux DJ, Helenius A, Mellman I. Spike--nucleocapsid interaction in Semliki Forest virus reconstructed using network antibodies. Nature. 336: 36-42. PMID 2460771 DOI: 10.1038/336036A0  0.633
1987 Helenius A, Doxsey S, Mellman I. Viruses as tools in drug delivery. Annals of the New York Academy of Sciences. 507: 1-6. PMID 3126693 DOI: 10.1111/J.1749-6632.1987.Tb45785.X  0.695
1987 Marsh M, Schmid S, Kern H, Harms E, Male P, Mellman I, Helenius A. Rapid analytical and preparative isolation of functional endosomes by free flow electrophoresis. The Journal of Cell Biology. 104: 875-86. PMID 3031085 DOI: 10.1083/Jcb.104.4.875  0.666
1987 Stuart SG, Trounstine ML, Vaux DJ, Koch T, Martens CL, Mellman I, Moore KW. Isolation and expression of cDNA clones encoding a human receptor for IgG (Fc gamma RII). The Journal of Experimental Medicine. 166: 1668-84. PMID 2824655 DOI: 10.1084/Jem.166.6.1668  0.321
1987 Green SA, Zimmer KP, Griffiths G, Mellman I. Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins Journal of Cell Biology. 105: 1227-1240. PMID 2821012 DOI: 10.1083/Jcb.105.3.1227  0.389
1987 Mellman I, Howe C, Helenius A. The Control of Membrane Traffic on the Endocytic Pathway Current Topics in Membranes and Transport. 29: 255-288. DOI: 10.1016/S0070-2161(08)60048-9  0.677
1986 Ukkonen P, Lewis V, Marsh M, Helenius A, Mellman I. Transport of macrophage Fc receptors and Fc receptor-bound ligands to lysosomes. The Journal of Experimental Medicine. 163: 952-71. PMID 3950548 DOI: 10.1084/Jem.163.4.952  0.664
1986 Marsh M, Griffiths G, Dean GE, Mellman I, Helenius A. Three-dimensional structure of endosomes in BHK-21 cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 2899-903. PMID 3458249 DOI: 10.1073/Pnas.83.9.2899  0.645
1986 Lewis VA, Koch T, Plutner H, Mellman I. A complementary DNA clone for a macrophage-lymphocyte Fc receptor Nature. 324: 372-375. PMID 3024012 DOI: 10.1038/324372A0  0.361
1986 Mellman I, Fuchs R, Helenius A. Acidification of the endocytic and exocytic pathways. Annual Review of Biochemistry. 55: 663-700. PMID 2874766 DOI: 10.1146/Annurev.Bi.55.070186.003311  0.606
1985 Horwich AL, Fenton WA, Firgaira FA, Fox JE, Kolansky D, Mellman IS, Rosenberg LE. Expression of amplified DNA sequences for ornithine transcarbamylase in HeLa cells: arginine residues may be required for mitochondrial import of enzyme precursor. The Journal of Cell Biology. 100: 1515-21. PMID 3988798 DOI: 10.1083/Jcb.100.5.1515  0.45
1985 Helenius A, Kielian M, Wellsteed J, Mellman I, Rudnick G. Effects of monovalent cations on Semliki Forest virus entry into BHK-21 cells. The Journal of Biological Chemistry. 260: 5691-7. PMID 3988769  0.613
1985 Lewis V, Green SA, Marsh M, Vihko P, Helenius A, Mellman I. Glycoproteins of the lysosomal membrane. The Journal of Cell Biology. 100: 1839-47. PMID 3922993 DOI: 10.1083/Jcb.100.6.1839  0.676
1985 Horwich AL, Kalousek F, Mellman I, Rosenberg LE. A leader peptide is sufficient to direct mitochondrial import of a chimeric protein. The Embo Journal. 4: 1129-35. PMID 3891325 DOI: 10.1002/J.1460-2075.1985.Tb03750.X  0.496
1984 Mellman I, Plutner H, Ukkonen P. Internalization and rapid recycling of macrophage Fc receptors tagged with monovalent antireceptor antibody: possible role of a prelysosomal compartment. The Journal of Cell Biology. 98: 1163-9. PMID 6715403 DOI: 10.1083/Jcb.98.4.1163  0.384
1984 Robbins AR, Oliver C, Bateman JL, Krag SS, Galloway CJ, Mellman I. A single mutation in Chinese hamster ovary cells impairs both Golgi and endosomal functions. The Journal of Cell Biology. 99: 1296-308. PMID 6480694 DOI: 10.1083/Jcb.99.4.1296  0.328
1983 Mellman IS, Plutner H, Steinman RM, Unkeless JC, Cohn ZA. Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis. The Journal of Cell Biology. 96: 887-95. PMID 6833386 DOI: 10.1083/Jcb.96.3.887  0.735
1983 Steinman RM, Mellman IS, Muller WA, Cohn ZA. Endocytosis and the recycling of plasma membrane. The Journal of Cell Biology. 96: 1-27. PMID 6298247 DOI: 10.1083/Jcb.96.1.1  0.714
1982 Mellman I. Multiple pathways of membrane transport. Nature. 299: 301-2. PMID 7110354 DOI: 10.1038/299301A0  0.318
1981 Kaplan G, Plutner H, Mellman I, Unkeless JC. Studies on externally disposed plasma membrane proteins. Trinitrobenzene sulfonic acid derivatization and immune precipitation. Experimental Cell Research. 133: 103-14. PMID 7016551 DOI: 10.1016/0014-4827(81)90361-X  0.33
1981 Sennett C, Rosenberg LE, Mellman IS. Transmembrane transport of cobalamin in prokaryotic and eukaryotic cells. Annual Review of Biochemistry. 50: 1053-86. PMID 6267986 DOI: 10.1146/annurev.bi.50.070181.005201  0.467
1980 Mellman IS, Steinman RM, Unkeless JC, Cohn ZA. Selective iodination and polypeptide composition of pinocytic vesicles. The Journal of Cell Biology. 86: 712-22. PMID 7410475 DOI: 10.1083/Jcb.86.3.712  0.744
1980 Steinman RM, Nogueira N, Witmer MD, Tydings JD, Mellman IS. Lymphokine enhances the expression and synthesis of Ia antigens on cultured mouse peritoneal macrophages. The Journal of Experimental Medicine. 152: 1248-61. PMID 6448907  0.605
1979 Youngdahl-Turner P, Mellman IS, Allen RH, Rosenberg LE. Protein mediated vitamin uptake. Adsorptive endocytosis of the transcobalamin II-cobalamin complex by cultured human fibroblasts. Experimental Cell Research. 118: 127-34. PMID 759210 DOI: 10.1016/0014-4827(79)90590-1  0.409
1979 Mellman I, Willard HF, Youngdahl-Turner P, Rosenberg LE. Cobalamin coenzyme synthesis in normal and mutant human fibroblasts. Evidence for a processing enzyme activity deficient in cblC cells. The Journal of Biological Chemistry. 254: 11847-53. PMID 500677  0.419
1979 Mellman IS, Lin PF, Ruddle FH, Rosenberg LE. Genetic control of cobalamin binding in normal and mutant cells: assignment of the gene for 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase to human chromosome 1. Proceedings of the National Academy of Sciences of the United States of America. 76: 405-9. PMID 284356  0.414
1978 Mellman I, Willard HF, Rosenberg LE. Cobalamin binding and cobalamin-dependent enzyme activity in normal and mutant human fibroblasts. The Journal of Clinical Investigation. 62: 952-60. PMID 30783 DOI: 10.1172/Jci109224  0.48
1978 Willard HF, Mellman IS, Rosenberg LE. Genetic complementation among inherited deficiencies of methylmalonyl-CoA mutase activity: evidence for a new class of human cobalamin mutant. American Journal of Human Genetics. 30: 1-13. PMID 23678  0.397
1977 Mellman IS, Youngdahl-Turner P, Willard HF, Rosenberg LE. Intracellular binding of radioactive hydroxocobalamin to cobalamin-dependent apoenzymes in rat liver. Proceedings of the National Academy of Sciences of the United States of America. 74: 916-20. PMID 15258  0.427
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