Hitoshi Okamoto - Publications

RIKEN Brain Science Institute, Wakō-shi, Saitama-ken, Japan 
Developmental Neurobiology, motoneuron, sensory neuron, zebrafish, habenula, brain asymmetry

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Chou MY, Amo R, Kinoshita M, Cherng BW, Shimazaki H, Agetsuma M, Shiraki T, Aoki T, Takahoko M, Yamazaki M, Higashijima S, Okamoto H. Social conflict resolution regulated by two dorsal habenular subregions in zebrafish. Science (New York, N.Y.). 352: 87-90. PMID 27034372 DOI: 10.1126/science.aac9508  1
2015 Aoki R, Tsuboi T, Okamoto H. Y-maze avoidance: an automated and rapid associative learning paradigm in zebrafish. Neuroscience Research. 91: 69-72. PMID 25449146 DOI: 10.1016/j.neures.2014.10.012  1
2014 Amo R, Fredes F, Kinoshita M, Aoki R, Aizawa H, Agetsuma M, Aoki T, Shiraki T, Kakinuma H, Matsuda M, Yamazaki M, Takahoko M, Tsuboi T, Higashijima S, Miyasaka N, ... ... Okamoto H, et al. The habenulo-raphe serotonergic circuit encodes an aversive expectation value essential for adaptive active avoidance of danger. Neuron. 84: 1034-48. PMID 25467985 DOI: 10.1016/j.neuron.2014.10.035  1
2014 Okamoto H. Minicerebellum, now available for reductionists' functional study. Proceedings of the National Academy of Sciences of the United States of America. 111: 11580-1. PMID 25074916 DOI: 10.1073/pnas.1411821111  1
2014 Nishiya N, Oku Y, Kumagai Y, Sato Y, Yamaguchi E, Sasaki A, Shoji M, Ohnishi Y, Okamoto H, Uehara Y. A zebrafish chemical suppressor screening identifies small molecule inhibitors of the Wnt/β-catenin pathway. Chemistry & Biology. 21: 530-40. PMID 24684907 DOI: 10.1016/j.chembiol.2014.02.015  1
2014 Aoki M, Segawa H, Naito M, Okamoto H. Identification of possible downstream genes required for the extension of peripheral axons in primary sensory neurons. Biochemical and Biophysical Research Communications. 445: 357-62. PMID 24513284 DOI: 10.1016/j.bbrc.2014.01.193  0.4
2013 Campbell DS, Okamoto H. Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization. The Journal of Cell Biology. 203: 657-72. PMID 24385488 DOI: 10.1083/jcb.201303072  1
2013 Mizuno H, Sassa T, Higashijima S, Okamoto H, Miyawaki A. Transgenic zebrafish for ratiometric imaging of cytosolic and mitochondrial Ca2+ response in teleost embryo. Cell Calcium. 54: 236-45. PMID 23906585 DOI: 10.1016/j.ceca.2013.06.007  1
2013 Aoki T, Kinoshita M, Aoki R, Agetsuma M, Aizawa H, Yamazaki M, Takahoko M, Amo R, Arata A, Higashijima S, Tsuboi T, Okamoto H. Imaging of neural ensemble for the retrieval of a learned behavioral program. Neuron. 78: 881-94. PMID 23684786 DOI: 10.1016/j.neuron.2013.04.009  1
2013 Aizawa H, Yanagihara S, Kobayashi M, Niisato K, Takekawa T, Harukuni R, McHugh TJ, Fukai T, Isomura Y, Okamoto H. The synchronous activity of lateral habenular neurons is essential for regulating hippocampal theta oscillation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 8909-21. PMID 23678132 DOI: 10.1523/JNEUROSCI.4369-12.2013  1
2013 Okamoto H, Aizawa H. Fear and anxiety regulation by conserved affective circuits. Neuron. 78: 411-3. PMID 23664609 DOI: 10.1016/j.neuron.2013.04.031  1
2012 Aizawa H, Kobayashi M, Tanaka S, Fukai T, Okamoto H. Molecular characterization of the subnuclei in rat habenula. The Journal of Comparative Neurology. 520: 4051-66. PMID 22700183 DOI: 10.1002/cne.23167  1
2012 Hiromi Y, Okamoto H, Wu CF. The Hotta neurogenetics school. Journal of Neurogenetics. 26: 1-2. PMID 22413932 DOI: 10.3109/01677063.2012.663427  1
2012 Higashijima S, Okamoto H. Yoshiki Hotta and the dawn of zebrafish molecular neurogenetics in Japan. Journal of Neurogenetics. 26: 28-33. PMID 22413917 DOI: 10.3109/01677063.2012.663426  1
2012 Okamoto H, Agetsuma M, Aizawa H. Genetic dissection of the zebrafish habenula, a possible switching board for selection of behavioral strategy to cope with fear and anxiety. Developmental Neurobiology. 72: 386-94. PMID 21567982 DOI: 10.1002/dneu.20913  1
2011 Aizawa H, Amo R, Okamoto H. Phylogeny and ontogeny of the habenular structure. Frontiers in Neuroscience. 5: 138. PMID 22203792 DOI: 10.3389/fnins.2011.00138  1
2011 Ohata S, Aoki R, Kinoshita S, Yamaguchi M, Tsuruoka-Kinoshita S, Tanaka H, Wada H, Watabe S, Tsuboi T, Masai I, Okamoto H. Dual roles of Notch in regulation of apically restricted mitosis and apicobasal polarity of neuroepithelial cells. Neuron. 69: 215-30. PMID 21262462 DOI: 10.1016/j.neuron.2010.12.026  0.32
2010 Agetsuma M, Aizawa H, Aoki T, Nakayama R, Takahoko M, Goto M, Sassa T, Amo R, Shiraki T, Kawakami K, Hosoya T, Higashijima S, Okamoto H. The habenula is crucial for experience-dependent modification of fear responses in zebrafish. Nature Neuroscience. 13: 1354-6. PMID 20935642 DOI: 10.1038/nn.2654  1
2010 Palmesino E, Rousso DL, Kao TJ, Klar A, Laufer E, Uemura O, Okamoto H, Novitch BG, Kania A. Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling. Plos Biology. 8: e1000446. PMID 20711475 DOI: 10.1371/journal.pbio.1000446  1
2010 Amo R, Aizawa H, Takahoko M, Kobayashi M, Takahashi R, Aoki T, Okamoto H. Identification of the zebrafish ventral habenula as a homolog of the mammalian lateral habenula. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1566-74. PMID 20107084 DOI: 10.1523/JNEUROSCI.3690-09.2010  1
2010 Yamazaki Y, Akashi R, Banno Y, Endo T, Ezura H, Fukami-Kobayashi K, Inaba K, Isa T, Kamei K, Kasai F, Kobayashi M, Kurata N, Kusaba M, Matuzawa T, Mitani S, ... ... Okamoto H, et al. NBRP databases: databases of biological resources in Japan. Nucleic Acids Research. 38: D26-32. PMID 19934255 DOI: 10.1093/nar/gkp996  1
2009 Sugiyama M, Sakaue-Sawano A, Iimura T, Fukami K, Kitaguchi T, Kawakami K, Okamoto H, Higashijima S, Miyawaki A. Illuminating cell-cycle progression in the developing zebrafish embryo. Proceedings of the National Academy of Sciences of the United States of America. 106: 20812-7. PMID 19923430 DOI: 10.1073/pnas.0906464106  1
2009 Miyasaka N, Morimoto K, Tsubokawa T, Higashijima S, Okamoto H, Yoshihara Y. From the olfactory bulb to higher brain centers: genetic visualization of secondary olfactory pathways in zebrafish. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4756-67. PMID 19369545 DOI: 10.1523/JNEUROSCI.0118-09.2009  1
2009 Soma M, Aizawa H, Ito Y, Maekawa M, Osumi N, Nakahira E, Okamoto H, Tanaka K, Yuasa S. Development of the mouse amygdala as revealed by enhanced green fluorescent protein gene transfer by means of in utero electroporation. The Journal of Comparative Neurology. 513: 113-28. PMID 19107806 DOI: 10.1002/cne.21945  1
2009 Carreira-Barbosa F, Kajita M, Kajita M, Morel V, Wada H, Okamoto H, Martinez Arias A, Fujita Y, Wilson SW, Tada M. Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation. Development (Cambridge, England). 136: 383-92. PMID 19091770 DOI: 10.1242/dev.026542  1
2008 Okamoto H. An interview with Hitoshi Okamoto, M.D., Ph.D. Interview by Stephen C. Ekker. Zebrafish. 5: 155-8. PMID 18945196 DOI: 10.1089/zeb.2008.9983  1
2008 Nishiwaki Y, Komori A, Sagara H, Suzuki E, Manabe T, Hosoya T, Nojima Y, Wada H, Tanaka H, Okamoto H, Masai I. Mutation of cGMP phosphodiesterase 6alpha'-subunit gene causes progressive degeneration of cone photoreceptors in zebrafish. Mechanisms of Development. 125: 932-46. PMID 18824093 DOI: 10.1016/j.mod.2008.09.001  1
2008 Yamaguchi M, Fujimori-Tonou N, Yoshimura Y, Kishi T, Okamoto H, Masai I. Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53. Development (Cambridge, England). 135: 1247-57. PMID 18287205 DOI: 10.1242/dev.011015  0.32
2007 Tanaka H, Maeda R, Shoji W, Wada H, Masai I, Shiraki T, Kobayashi M, Nakayama R, Okamoto H. Novel mutations affecting axon guidance in zebrafish and a role for plexin signalling in the guidance of trigeminal and facial nerve axons. Development (Cambridge, England). 134: 3259-69. PMID 17699608 DOI: 10.1242/dev.004267  0.32
2007 Sato T, Hamaoka T, Aizawa H, Hosoya T, Okamoto H. Genetic single-cell mosaic analysis implicates ephrinB2 reverse signaling in projections from the posterior tectum to the hindbrain in zebrafish. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5271-9. PMID 17507550 DOI: 10.1523/JNEUROSCI.0883-07.2007  1
2007 Sassa T, Aizawa H, Okamoto H. Visualization of two distinct classes of neurons by gad2 and zic1 promoter/enhancer elements in the dorsal hindbrain of developing zebrafish reveals neuronal connectivity related to the auditory and lateral line systems. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 706-18. PMID 17279576 DOI: 10.1002/dvdy.21084  1
2005 Ando H, Kobayashi M, Tsubokawa T, Uyemura K, Furuta T, Okamoto H. Lhx2 mediates the activity of Six3 in zebrafish forebrain growth. Developmental Biology. 287: 456-68. PMID 16226737 DOI: 10.1016/j.ydbio.2005.09.023  1
2005 Yamaguchi M, Tonou-Fujimori N, Komori A, Maeda R, Nojima Y, Li H, Okamoto H, Masai I. Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways. Development (Cambridge, England). 132: 3027-43. PMID 15944187 DOI: 10.1242/dev.01881  0.32
2005 Wada H, Iwasaki M, Sato T, Masai I, Nishiwaki Y, Tanaka H, Sato A, Nojima Y, Okamoto H. Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos. Development (Cambridge, England). 132: 2273-85. PMID 15829519 DOI: 10.1242/dev.01810  0.32
2005 Kawakami A, Nojima Y, Toyoda A, Takahoko M, Satoh M, Tanaka H, Wada H, Masai I, Terasaki H, Sakaki Y, Takeda H, Okamoto H. The zebrafish-secreted matrix protein you/scube2 is implicated in long-range regulation of hedgehog signaling. Current Biology : Cb. 15: 480-8. PMID 15753045 DOI: 10.1016/j.cub.2005.02.018  0.32
2005 Masai I, Yamaguchi M, Tonou-Fujimori N, Komori A, Okamoto H. The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation. Development (Cambridge, England). 132: 1539-53. PMID 15728672 DOI: 10.1242/dev.01714  0.32
2005 Li Q, Shirabe K, Thisse C, Thisse B, Okamoto H, Masai I, Kuwada JY. Chemokine signaling guides axons within the retina in zebrafish. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1711-7. PMID 15716407 DOI: 10.1523/JNEUROSCI.4393-04.2005  1
2005 Miyasaka N, Sato Y, Yeo SY, Hutson LD, Chien CB, Okamoto H, Yoshihara Y. Robo2 is required for establishment of a precise glomerular map in the zebrafish olfactory system. Development (Cambridge, England). 132: 1283-93. PMID 15716341 DOI: 10.1242/dev.01698  1
2005 Aizawa H, Bianco IH, Hamaoka T, Miyashita T, Uemura O, Concha ML, Russell C, Wilson SW, Okamoto H. Laterotopic representation of left-right information onto the dorso-ventral axis of a zebrafish midbrain target nucleus. Current Biology : Cb. 15: 238-43. PMID 15694307 DOI: 10.1016/j.cub.2005.01.014  1
2005 Uemura O, Okada Y, Ando H, Guedj M, Higashijima S, Shimazaki T, Chino N, Okano H, Okamoto H. Comparative functional genomics revealed conservation and diversification of three enhancers of the isl1 gene for motor and sensory neuron-specific expression. Developmental Biology. 278: 587-606. PMID 15680372 DOI: 10.1016/j.ydbio.2004.11.031  1
2004 Hanaoka R, Ohmori Y, Uyemura K, Hosoya T, Hotta Y, Shirao T, Okamoto H. Zebrafish gcmb is required for pharyngeal cartilage formation. Mechanisms of Development. 121: 1235-47. PMID 15327784 DOI: 10.1016/j.mod.2004.05.011  1
2004 Miyashita T, Yeo SY, Hirate Y, Segawa H, Wada H, Little MH, Yamada T, Takahashi N, Okamoto H. PlexinA4 is necessary as a downstream target of Islet2 to mediate Slit signaling for promotion of sensory axon branching. Development (Cambridge, England). 131: 3705-15. PMID 15229183 DOI: 10.1242/dev.01228  1
2004 Yeo SY, Miyashita T, Fricke C, Little MH, Yamada T, Kuwada JY, Huh TL, Chien CB, Okamoto H. Involvement of Islet-2 in the Slit signaling for axonal branching and defasciculation of the sensory neurons in embryonic zebrafish. Mechanisms of Development. 121: 315-24. PMID 15110042 DOI: 10.1016/j.mod.2004.03.006  1
2004 Okamoto H, Uemura O. [The Islet-1 family in subtype specification of motor neurons]. Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. 49: 241-6. PMID 14976736  1
2003 Hutson LD, Jurynec MJ, Yeo SY, Okamoto H, Chien CB. Two divergent slit1 genes in zebrafish. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 228: 358-69. PMID 14579375 DOI: 10.1002/dvdy.10386  1
2003 Masai I, Lele Z, Yamaguchi M, Komori A, Nakata A, Nishiwaki Y, Wada H, Tanaka H, Nojima Y, Hammerschmidt M, Wilson SW, Okamoto H. N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neurites. Development (Cambridge, England). 130: 2479-94. PMID 12702661 DOI: 10.1242/dev.00465  1
2002 Zeller J, Schneider V, Malayaman S, Higashijima S, Okamoto H, Gui J, Lin S, Granato M. Migration of zebrafish spinal motor nerves into the periphery requires multiple myotome-derived cues. Developmental Biology. 252: 241-56. PMID 12482713 DOI: 10.1006/dbio.2002.0852  1
2002 Bingham S, Higashijima S, Okamoto H, Chandrasekhar A. The Zebrafish trilobite gene is essential for tangential migration of branchiomotor neurons. Developmental Biology. 242: 149-60. PMID 11820812 DOI: 10.1006/dbio.2001.0532  1
2001 Segawa H, Miyashita T, Hirate Y, Higashijima S, Chino N, Uyemura K, Kikuchi Y, Okamoto H. Functional repression of Islet-2 by disruption of complex with Ldb impairs peripheral axonal outgrowth in embryonic zebrafish. Neuron. 30: 423-36. PMID 11395004 DOI: 10.1016/S0896-6273(01)00283-5  1
2001 Yeo SY, Little MH, Yamada T, Miyashita T, Halloran MC, Kuwada JY, Huh TL, Okamoto H. Overexpression of a slit homologue impairs convergent extension of the mesoderm and causes cyclopia in embryonic zebrafish. Developmental Biology. 230: 1-17. PMID 11161558 DOI: 10.1006/dbio.2000.0105  1
2000 Masai I, Stemple DL, Okamoto H, Wilson SW. Midline signals regulate retinal neurogenesis in zebrafish. Neuron. 27: 251-63. PMID 10985346  1
2000 Higashijima S, Hotta Y, Okamoto H. Visualization of cranial motor neurons in live transgenic zebrafish expressing green fluorescent protein under the control of the islet-1 promoter/enhancer. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 206-18. PMID 10627598  1
1999 Mieda M, Kikuchi Y, Hirate Y, Aoki M, Okamoto H. Compartmentalized expression of zebrafish ten-m3 and ten-m4, homologues of the Drosophila ten(m)/odd Oz gene, in the central nervous system. Mechanisms of Development. 87: 223-7. PMID 10495292  0.4
1997 Higashijima S, Okamoto H, Ueno N, Hotta Y, Eguchi G. High-frequency generation of transgenic zebrafish which reliably express GFP in whole muscles or the whole body by using promoters of zebrafish origin. Developmental Biology. 192: 289-99. PMID 9441668 DOI: 10.1006/dbio.1997.8779  1
1997 Higashijima S, Nose A, Eguchi G, Hotta Y, Okamoto H. Mindin/F-spondin family: novel ECM proteins expressed in the zebrafish embryonic axis. Developmental Biology. 192: 211-27. PMID 9441663 DOI: 10.1006/dbio.1997.8760  1
1997 Kikuchi Y, Segawa H, Tokumoto M, Tsubokawa T, Hotta Y, Uyemura K, Okamoto H. Ocular and cerebellar defects in zebrafish induced by overexpression of the LIM domains of the islet-3 LIM/homeodomain protein. Neuron. 18: 369-82. PMID 9115732 DOI: 10.1016/S0896-6273(00)81239-8  1
1996 Kim CH, Taira E, Kuo CH, Li BS, Okamoto H, Nakahira K, Ikenaka K, Higuchi H, Miki N. Neuron-specific expression of a chicken gicerin cDNA in transient transgenic zebrafish Neurochemical Research. 21: 231-237. PMID 9182247 DOI: 10.1007/BF02529139  1
1995 Tokumoto M, Gong Z, Tsubokawa T, Hew CL, Uyemura K, Hotta Y, Okamoto H. Molecular heterogeneity among primary motoneurons and within myotomes revealed by the differential mRNA expression of novel islet-1 homologs in embryonic zebrafish. Developmental Biology. 171: 578-89. PMID 7556938 DOI: 10.1006/dbio.1995.1306  1
1994 Inoue A, Takahashi M, Hatta K, Hotta Y, Okamoto H. Developmental regulation of islet-1 mRNA expression during neuronal differentiation in embryonic zebrafish. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 199: 1-11. PMID 8167375 DOI: 10.1002/aja.1001990102  1
1991 Okamoto H, Kuwada JY. Alteration of pectoral fin nerves following ablation of fin buds and by ectopic fin buds in the Japanese medaka fish. Developmental Biology. 146: 62-71. PMID 2060711 DOI: 10.1016/0012-1606(91)90446-A  1
1991 Okamoto H, Kuwada JY. Outgrowth by fin motor axons in wildtype and a finless mutant of the Japanese medaka fish. Developmental Biology. 146: 49-61. PMID 2060710 DOI: 10.1016/0012-1606(91)90445-9  1
1986 Hiromi Y, Okamoto H, Gehring WJ, Hotta Y. Germline transformation with Drosophila mutant actin genes induces constitutive expression of heat shock genes. Cell. 44: 293-301. PMID 3080247 DOI: 10.1016/0092-8674(86)90763-4  1
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