Morgan DeSantis - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 

12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Guo L, Kim HJ, Wang H, Monaghan J, Freyermuth F, Sung JC, O'Donovan K, Fare CM, Diaz Z, Singh N, Zhang ZC, Coughlin M, Sweeny EA, DeSantis ME, Jackrel ME, et al. Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains. Cell. 173: 677-692.e20. PMID 29677512 DOI: 10.1016/j.cell.2018.03.002  0.76
2015 Sweeny EA, Jackrel ME, Go MS, Sochor MA, Razzo BM, DeSantis ME, Gupta K, Shorter J. The Hsp104 N-terminal domain enables disaggregase plasticity and potentiation. Molecular Cell. 57: 836-49. PMID 25620563 DOI: 10.1016/j.molcel.2014.12.021  0.76
2014 Jackrel ME, DeSantis ME, Martinez BA, Castellano LM, Stewart RM, Caldwell KA, Caldwell GA, Shorter J. Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events. Cell. 156: 170-82. PMID 24439375 DOI: 10.1016/j.cell.2013.11.047  0.76
2014 Desantis ME, Sweeny EA, Snead D, Leung EH, Go MS, Gupta K, Wendler P, Shorter J. Conserved distal loop residues in the Hsp104 and ClpB middle domain contact nucleotide-binding domain 2 and enable Hsp70-dependent protein disaggregation. The Journal of Biological Chemistry. 289: 848-67. PMID 24280225 DOI: 10.1074/jbc.M113.520759  0.76
2013 Coelho M, Dereli A, Haese A, Kühn S, Malinovska L, DeSantis ME, Shorter J, Alberti S, Gross T, Tolić-Nørrelykke IM. Fission yeast does not age under favorable conditions, but does so after stress. Current Biology : Cb. 23: 1844-52. PMID 24035542 DOI: 10.1016/j.cub.2013.07.084  0.76
2012 Desantis ME, Shorter J. Hsp104 drives "protein-only" positive selection of sup35 prion strains encoding strong [PSI+] Chemistry and Biology. 19: 1400-1410. PMID 23177195 DOI: 10.1016/j.chembiol.2012.09.013  0.76
2012 DeSantis ME, Leung EH, Sweeny EA, Jackrel ME, Cushman-Nick M, Neuhaus-Follini A, Vashist S, Sochor MA, Knight MN, Shorter J. Operational plasticity enables hsp104 to disaggregate diverse amyloid and nonamyloid clients. Cell. 151: 778-93. PMID 23141537 DOI: 10.1016/j.cell.2012.09.038  0.76
2012 Acchione M, Lee YC, Desantis ME, Lipschultz CA, Wlodawer A, Li M, Shanmuganathan A, Walter RL, Smith-Gill S, Barchi JJ. Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics Biochemistry. 51: 6017-6027. PMID 22769726 DOI: 10.1021/bi300455t  0.76
2012 DeSantis ME, Shorter J. The elusive middle domain of Hsp104 and ClpB: Location and function Biochimica Et Biophysica Acta - Molecular Cell Research. 1823: 29-39. PMID 21843558 DOI: 10.1016/j.bbamcr.2011.07.014  0.76
2011 Sweeny EA, DeSantis ME, Shorter J. Purification of hsp104, a protein disaggregase Journal of Visualized Experiments : Jove. PMID 21989490 DOI: 10.3791/3190  0.76
2009 Acchione M, Lipschultz CA, DeSantis ME, Shanmuganathan A, Li M, Wlodawer A, Tarasov S, Smith-Gill SJ. Light chain somatic mutations change thermodynamics of binding and water coordination in the HyHEL-10 family of antibodies. Molecular Immunology. 47: 457-64. PMID 19781789 DOI: 10.1016/j.molimm.2009.08.018  0.76
2009 Mohan S, Kourentzi K, Schick KA, Uehara C, Lipschultz CA, Acchione M, DeSantis ME, Smith-Gill SJ, Willson RC. Association energetics of cross-reactive and specific antibodies Biochemistry. 48: 1390-1398. PMID 19166328 DOI: 10.1021/bi801901d  0.76
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